Amino acid dipepetide frequency for Paracoccus siganidrum

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.988AlaAla: 19.988 ± 0.175	1.049AlaCys: 1.049 ± 0.026	7.297AlaAsp: 7.297 ± 0.077	9.206AlaGlu: 9.206 ± 0.091	4.239AlaPhe: 4.239 ± 0.059	12.808AlaGly: 12.808 ± 0.1	2.547AlaHis: 2.547 ± 0.049	6.415AlaIle: 6.415 ± 0.063	2.691AlaLys: 2.691 ± 0.055	15.02AlaLeu: 15.02 ± 0.118	4.054AlaMet: 4.054 ± 0.062	2.425AlaAsn: 2.425 ± 0.047	6.695AlaPro: 6.695 ± 0.082	4.729AlaGln: 4.729 ± 0.062	11.241AlaArg: 11.241 ± 0.119	5.601AlaSer: 5.601 ± 0.068	5.93AlaThr: 5.93 ± 0.073	8.48AlaVal: 8.48 ± 0.083	1.629AlaTrp: 1.629 ± 0.036	2.257AlaTyr: 2.257 ± 0.038	0.0AlaXaa: 0.0 ± 0.0
Cys	1.055CysAla: 1.055 ± 0.025	0.132CysCys: 0.132 ± 0.011	0.557CysAsp: 0.557 ± 0.018	0.404CysGlu: 0.404 ± 0.018	0.311CysPhe: 0.311 ± 0.014	0.948CysGly: 0.948 ± 0.026	0.265CysHis: 0.265 ± 0.014	0.385CysIle: 0.385 ± 0.016	0.156CysLys: 0.156 ± 0.011	0.875CysLeu: 0.875 ± 0.023	0.162CysMet: 0.162 ± 0.011	0.187CysAsn: 0.187 ± 0.011	0.544CysPro: 0.544 ± 0.021	0.221CysGln: 0.221 ± 0.013	0.68CysArg: 0.68 ± 0.027	0.422CysSer: 0.422 ± 0.017	0.358CysThr: 0.358 ± 0.017	0.513CysVal: 0.513 ± 0.021	0.142CysTrp: 0.142 ± 0.009	0.178CysTyr: 0.178 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	7.25AspAla: 7.25 ± 0.086	0.537AspCys: 0.537 ± 0.018	3.146AspAsp: 3.146 ± 0.054	3.374AspGlu: 3.374 ± 0.051	2.333AspPhe: 2.333 ± 0.042	5.522AspGly: 5.522 ± 0.075	1.501AspHis: 1.501 ± 0.032	2.682AspIle: 2.682 ± 0.039	1.147AspLys: 1.147 ± 0.031	6.623AspLeu: 6.623 ± 0.08	1.484AspMet: 1.484 ± 0.033	1.047AspAsn: 1.047 ± 0.026	4.285AspPro: 4.285 ± 0.062	1.992AspGln: 1.992 ± 0.037	5.195AspArg: 5.195 ± 0.069	2.352AspSer: 2.352 ± 0.048	2.221AspThr: 2.221 ± 0.046	3.395AspVal: 3.395 ± 0.053	1.266AspTrp: 1.266 ± 0.03	1.547AspTyr: 1.547 ± 0.03	0.0AspXaa: 0.0 ± 0.0
Glu	8.572GluAla: 8.572 ± 0.097	0.355GluCys: 0.355 ± 0.018	3.196GluAsp: 3.196 ± 0.051	3.199GluGlu: 3.199 ± 0.055	1.7GluPhe: 1.7 ± 0.032	5.118GluGly: 5.118 ± 0.063	1.031GluHis: 1.031 ± 0.029	3.525GluIle: 3.525 ± 0.054	1.561GluLys: 1.561 ± 0.035	5.402GluLeu: 5.402 ± 0.062	1.678GluMet: 1.678 ± 0.036	1.488GluAsn: 1.488 ± 0.033	2.594GluPro: 2.594 ± 0.047	1.799GluGln: 1.799 ± 0.041	4.333GluArg: 4.333 ± 0.064	2.128GluSer: 2.128 ± 0.041	3.302GluThr: 3.302 ± 0.055	3.88GluVal: 3.88 ± 0.06	0.794GluTrp: 0.794 ± 0.025	0.991GluTyr: 0.991 ± 0.027	0.0GluXaa: 0.0 ± 0.0
Phe	4.576PheAla: 4.576 ± 0.067	0.379PheCys: 0.379 ± 0.016	2.614PheAsp: 2.614 ± 0.047	1.827PheGlu: 1.827 ± 0.038	1.299PhePhe: 1.299 ± 0.037	3.592PheGly: 3.592 ± 0.057	0.807PheHis: 0.807 ± 0.026	1.509PheIle: 1.509 ± 0.033	0.626PheLys: 0.626 ± 0.02	3.421PheLeu: 3.421 ± 0.056	0.809PheMet: 0.809 ± 0.024	0.853PheAsn: 0.853 ± 0.021	1.601PhePro: 1.601 ± 0.031	1.019PheGln: 1.019 ± 0.024	2.534PheArg: 2.534 ± 0.044	1.855PheSer: 1.855 ± 0.039	1.931PheThr: 1.931 ± 0.038	2.417PheVal: 2.417 ± 0.046	0.611PheTrp: 0.611 ± 0.023	0.787PheTyr: 0.787 ± 0.023	0.0PheXaa: 0.0 ± 0.0
Gly	10.913GlyAla: 10.913 ± 0.106	0.886GlyCys: 0.886 ± 0.022	4.812GlyAsp: 4.812 ± 0.074	4.709GlyGlu: 4.709 ± 0.064	3.827GlyPhe: 3.827 ± 0.054	8.128GlyGly: 8.128 ± 0.113	2.159GlyHis: 2.159 ± 0.043	4.751GlyIle: 4.751 ± 0.066	2.551GlyLys: 2.551 ± 0.057	9.992GlyLeu: 9.992 ± 0.101	2.765GlyMet: 2.765 ± 0.048	2.104GlyAsn: 2.104 ± 0.052	4.219GlyPro: 4.219 ± 0.054	3.521GlyGln: 3.521 ± 0.054	7.339GlyArg: 7.339 ± 0.074	4.338GlySer: 4.338 ± 0.058	4.512GlyThr: 4.512 ± 0.064	6.105GlyVal: 6.105 ± 0.058	1.731GlyTrp: 1.731 ± 0.036	2.134GlyTyr: 2.134 ± 0.042	0.0GlyXaa: 0.0 ± 0.0
His	2.564HisAla: 2.564 ± 0.043	0.228HisCys: 0.228 ± 0.013	1.45HisAsp: 1.45 ± 0.034	1.072HisGlu: 1.072 ± 0.026	0.827HisPhe: 0.827 ± 0.026	2.107HisGly: 2.107 ± 0.039	0.59HisHis: 0.59 ± 0.023	0.84HisIle: 0.84 ± 0.021	0.386HisLys: 0.386 ± 0.015	2.305HisLeu: 2.305 ± 0.044	0.544HisMet: 0.544 ± 0.02	0.391HisAsn: 0.391 ± 0.015	1.534HisPro: 1.534 ± 0.035	0.614HisGln: 0.614 ± 0.018	1.628HisArg: 1.628 ± 0.04	0.912HisSer: 0.912 ± 0.026	0.624HisThr: 0.624 ± 0.022	1.679HisVal: 1.679 ± 0.035	0.335HisTrp: 0.335 ± 0.013	0.542HisTyr: 0.542 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	7.592IleAla: 7.592 ± 0.066	0.604IleCys: 0.604 ± 0.02	3.315IleAsp: 3.315 ± 0.045	3.449IleGlu: 3.449 ± 0.055	1.683IlePhe: 1.683 ± 0.04	5.131IleGly: 5.131 ± 0.059	1.015IleHis: 1.015 ± 0.027	1.986IleIle: 1.986 ± 0.037	0.886IleLys: 0.886 ± 0.027	4.749IleLeu: 4.749 ± 0.074	1.037IleMet: 1.037 ± 0.031	1.11IleAsn: 1.11 ± 0.03	2.396IlePro: 2.396 ± 0.048	1.087IleGln: 1.087 ± 0.027	3.99IleArg: 3.99 ± 0.053	2.647IleSer: 2.647 ± 0.039	2.616IleThr: 2.616 ± 0.042	3.579IleVal: 3.579 ± 0.056	0.742IleTrp: 0.742 ± 0.025	1.045IleTyr: 1.045 ± 0.028	0.0IleXaa: 0.0 ± 0.0
Lys	3.019LysAla: 3.019 ± 0.06	0.134LysCys: 0.134 ± 0.009	1.249LysAsp: 1.249 ± 0.034	1.077LysGlu: 1.077 ± 0.027	0.637LysPhe: 0.637 ± 0.023	2.121LysGly: 2.121 ± 0.048	0.426LysHis: 0.426 ± 0.017	1.196LysIle: 1.196 ± 0.033	0.721LysLys: 0.721 ± 0.031	2.313LysLeu: 2.313 ± 0.053	0.574LysMet: 0.574 ± 0.02	0.51LysAsn: 0.51 ± 0.021	1.447LysPro: 1.447 ± 0.036	0.728LysGln: 0.728 ± 0.022	1.653LysArg: 1.653 ± 0.037	1.212LysSer: 1.212 ± 0.033	1.32LysThr: 1.32 ± 0.032	1.674LysVal: 1.674 ± 0.04	0.294LysTrp: 0.294 ± 0.016	0.458LysTyr: 0.458 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	15.57LeuAla: 15.57 ± 0.136	0.923LeuCys: 0.923 ± 0.025	6.192LeuAsp: 6.192 ± 0.075	5.172LeuGlu: 5.172 ± 0.065	3.365LeuPhe: 3.365 ± 0.057	8.855LeuGly: 8.855 ± 0.085	2.045LeuHis: 2.045 ± 0.036	5.199LeuIle: 5.199 ± 0.073	2.498LeuLys: 2.498 ± 0.042	9.749LeuLeu: 9.749 ± 0.121	2.659LeuMet: 2.659 ± 0.047	2.405LeuAsn: 2.405 ± 0.043	6.552LeuPro: 6.552 ± 0.081	2.848LeuGln: 2.848 ± 0.05	8.345LeuArg: 8.345 ± 0.089	6.199LeuSer: 6.199 ± 0.076	5.762LeuThr: 5.762 ± 0.062	7.228LeuVal: 7.228 ± 0.086	1.328LeuTrp: 1.328 ± 0.032	1.858LeuTyr: 1.858 ± 0.038	0.0LeuXaa: 0.0 ± 0.0
Met	3.82MetAla: 3.82 ± 0.058	0.171MetCys: 0.171 ± 0.012	1.289MetAsp: 1.289 ± 0.031	1.214MetGlu: 1.214 ± 0.029	0.741MetPhe: 0.741 ± 0.022	2.206MetGly: 2.206 ± 0.043	0.406MetHis: 0.406 ± 0.015	1.541MetIle: 1.541 ± 0.031	0.845MetLys: 0.845 ± 0.024	2.725MetLeu: 2.725 ± 0.051	0.69MetMet: 0.69 ± 0.024	0.817MetAsn: 0.817 ± 0.023	1.547MetPro: 1.547 ± 0.034	0.923MetGln: 0.923 ± 0.024	2.16MetArg: 2.16 ± 0.037	1.614MetSer: 1.614 ± 0.033	1.919MetThr: 1.919 ± 0.043	1.848MetVal: 1.848 ± 0.036	0.23MetTrp: 0.23 ± 0.012	0.291MetTyr: 0.291 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	2.761AsnAla: 2.761 ± 0.047	0.244AsnCys: 0.244 ± 0.014	1.317AsnAsp: 1.317 ± 0.04	1.01AsnGlu: 1.01 ± 0.031	0.82AsnPhe: 0.82 ± 0.025	2.014AsnGly: 2.014 ± 0.042	0.457AsnHis: 0.457 ± 0.016	1.261AsnIle: 1.261 ± 0.03	0.432AsnLys: 0.432 ± 0.02	2.328AsnLeu: 2.328 ± 0.041	0.601AsnMet: 0.601 ± 0.02	0.545AsnAsn: 0.545 ± 0.023	1.747AsnPro: 1.747 ± 0.034	0.652AsnGln: 0.652 ± 0.022	1.778AsnArg: 1.778 ± 0.037	1.014AsnSer: 1.014 ± 0.036	0.997AsnThr: 0.997 ± 0.026	1.554AsnVal: 1.554 ± 0.036	0.431AsnTrp: 0.431 ± 0.017	0.538AsnTyr: 0.538 ± 0.02	0.0AsnXaa: 0.0 ± 0.0
Pro	7.56ProAla: 7.56 ± 0.09	0.369ProCys: 0.369 ± 0.016	4.316ProAsp: 4.316 ± 0.066	4.43ProGlu: 4.43 ± 0.061	1.957ProPhe: 1.957 ± 0.034	5.527ProGly: 5.527 ± 0.06	1.192ProHis: 1.192 ± 0.03	2.134ProIle: 2.134 ± 0.037	1.194ProLys: 1.194 ± 0.031	5.192ProLeu: 5.192 ± 0.072	1.354ProMet: 1.354 ± 0.029	1.104ProAsn: 1.104 ± 0.029	2.765ProPro: 2.765 ± 0.054	2.004ProGln: 2.004 ± 0.036	3.65ProArg: 3.65 ± 0.057	2.422ProSer: 2.422 ± 0.043	2.159ProThr: 2.159 ± 0.041	4.574ProVal: 4.574 ± 0.059	0.742ProTrp: 0.742 ± 0.025	1.014ProTyr: 1.014 ± 0.027	0.0ProXaa: 0.0 ± 0.0
Gln	4.59GlnAla: 4.59 ± 0.064	0.174GlnCys: 0.174 ± 0.012	1.744GlnAsp: 1.744 ± 0.038	1.536GlnGlu: 1.536 ± 0.034	0.947GlnPhe: 0.947 ± 0.024	2.992GlnGly: 2.992 ± 0.043	0.571GlnHis: 0.571 ± 0.02	1.974GlnIle: 1.974 ± 0.039	0.883GlnLys: 0.883 ± 0.028	3.032GlnLeu: 3.032 ± 0.043	1.049GlnMet: 1.049 ± 0.026	0.803GlnAsn: 0.803 ± 0.026	2.049GlnPro: 2.049 ± 0.042	1.267GlnGln: 1.267 ± 0.029	2.487GlnArg: 2.487 ± 0.049	1.509GlnSer: 1.509 ± 0.032	1.538GlnThr: 1.538 ± 0.031	2.542GlnVal: 2.542 ± 0.042	0.364GlnTrp: 0.364 ± 0.014	0.545GlnTyr: 0.545 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	9.806ArgAla: 9.806 ± 0.107	0.553ArgCys: 0.553 ± 0.019	4.998ArgAsp: 4.998 ± 0.063	4.151ArgGlu: 4.151 ± 0.056	2.899ArgPhe: 2.899 ± 0.052	5.575ArgGly: 5.575 ± 0.071	2.077ArgHis: 2.077 ± 0.037	4.877ArgIle: 4.877 ± 0.061	1.962ArgLys: 1.962 ± 0.042	9.153ArgLeu: 9.153 ± 0.095	2.288ArgMet: 2.288 ± 0.042	1.888ArgAsn: 1.888 ± 0.033	4.463ArgPro: 4.463 ± 0.073	2.99ArgGln: 2.99 ± 0.049	6.659ArgArg: 6.659 ± 0.099	3.392ArgSer: 3.392 ± 0.048	2.914ArgThr: 2.914 ± 0.048	4.92ArgVal: 4.92 ± 0.06	1.108ArgTrp: 1.108 ± 0.031	1.505ArgTyr: 1.505 ± 0.032	0.0ArgXaa: 0.0 ± 0.0
Ser	5.658SerAla: 5.658 ± 0.067	0.436SerCys: 0.436 ± 0.018	2.854SerAsp: 2.854 ± 0.047	2.353SerGlu: 2.353 ± 0.04	2.075SerPhe: 2.075 ± 0.037	5.369SerGly: 5.369 ± 0.064	1.02SerHis: 1.02 ± 0.025	2.33SerIle: 2.33 ± 0.041	0.966SerLys: 0.966 ± 0.03	4.873SerLeu: 4.873 ± 0.068	1.189SerMet: 1.189 ± 0.029	1.07SerAsn: 1.07 ± 0.03	2.596SerPro: 2.596 ± 0.047	1.464SerGln: 1.464 ± 0.027	3.61SerArg: 3.61 ± 0.048	2.195SerSer: 2.195 ± 0.044	2.164SerThr: 2.164 ± 0.043	3.338SerVal: 3.338 ± 0.047	0.762SerTrp: 0.762 ± 0.024	1.128SerTyr: 1.128 ± 0.028	0.0SerXaa: 0.0 ± 0.0
Thr	5.835ThrAla: 5.835 ± 0.063	0.449ThrCys: 0.449 ± 0.017	2.777ThrAsp: 2.777 ± 0.047	2.67ThrGlu: 2.67 ± 0.044	1.534ThrPhe: 1.534 ± 0.033	5.278ThrGly: 5.278 ± 0.066	1.027ThrHis: 1.027 ± 0.024	2.52ThrIle: 2.52 ± 0.043	0.863ThrLys: 0.863 ± 0.028	5.273ThrLeu: 5.273 ± 0.064	1.138ThrMet: 1.138 ± 0.027	1.073ThrAsn: 1.073 ± 0.035	3.209ThrPro: 3.209 ± 0.045	1.296ThrGln: 1.296 ± 0.034	3.653ThrArg: 3.653 ± 0.044	2.236ThrSer: 2.236 ± 0.043	2.492ThrThr: 2.492 ± 0.047	3.92ThrVal: 3.92 ± 0.062	0.621ThrTrp: 0.621 ± 0.023	0.943ThrTyr: 0.943 ± 0.026	0.0ThrXaa: 0.0 ± 0.0
Val	9.442ValAla: 9.442 ± 0.08	0.529ValCys: 0.529 ± 0.02	3.567ValAsp: 3.567 ± 0.051	4.144ValGlu: 4.144 ± 0.06	2.548ValPhe: 2.548 ± 0.044	5.163ValGly: 5.163 ± 0.07	1.196ValHis: 1.196 ± 0.031	4.051ValIle: 4.051 ± 0.053	1.63ValLys: 1.63 ± 0.035	7.651ValLeu: 7.651 ± 0.08	2.116ValMet: 2.116 ± 0.038	1.765ValAsn: 1.765 ± 0.04	3.6ValPro: 3.6 ± 0.05	2.009ValGln: 2.009 ± 0.034	4.241ValArg: 4.241 ± 0.06	3.671ValSer: 3.671 ± 0.06	4.371ValThr: 4.371 ± 0.058	5.266ValVal: 5.266 ± 0.069	0.97ValTrp: 0.97 ± 0.028	1.23ValTyr: 1.23 ± 0.027	0.0ValXaa: 0.0 ± 0.0
Trp	1.425TrpAla: 1.425 ± 0.032	0.135TrpCys: 0.135 ± 0.01	0.756TrpAsp: 0.756 ± 0.024	0.61TrpGlu: 0.61 ± 0.023	0.576TrpPhe: 0.576 ± 0.02	1.083TrpGly: 1.083 ± 0.024	0.363TrpHis: 0.363 ± 0.017	0.772TrpIle: 0.772 ± 0.025	0.379TrpLys: 0.379 ± 0.015	1.949TrpLeu: 1.949 ± 0.036	0.385TrpMet: 0.385 ± 0.017	0.425TrpAsn: 0.425 ± 0.016	0.779TrpPro: 0.779 ± 0.024	0.786TrpGln: 0.786 ± 0.024	1.332TrpArg: 1.332 ± 0.033	0.765TrpSer: 0.765 ± 0.022	0.814TrpThr: 0.814 ± 0.026	0.828TrpVal: 0.828 ± 0.024	0.24TrpTrp: 0.24 ± 0.012	0.256TrpTyr: 0.256 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.302TyrAla: 2.302 ± 0.041	0.209TyrCys: 0.209 ± 0.013	1.453TyrAsp: 1.453 ± 0.036	1.04TyrGlu: 1.04 ± 0.03	0.748TyrPhe: 0.748 ± 0.023	1.956TyrGly: 1.956 ± 0.04	0.477TyrHis: 0.477 ± 0.02	0.713TyrIle: 0.713 ± 0.023	0.389TyrLys: 0.389 ± 0.018	2.128TyrLeu: 2.128 ± 0.041	0.421TyrMet: 0.421 ± 0.016	0.492TyrAsn: 0.492 ± 0.024	1.038TyrPro: 1.038 ± 0.029	0.646TyrGln: 0.646 ± 0.023	1.671TyrArg: 1.671 ± 0.04	0.963TyrSer: 0.963 ± 0.03	0.862TyrThr: 0.862 ± 0.026	1.421TyrVal: 1.421 ± 0.03	0.317TyrTrp: 0.317 ± 0.015	0.499TyrTyr: 0.499 ± 0.018	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4665 proteins (1441716 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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