Amino acid dipepetide frequency for Peach associated luteovirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.261AlaAla: 3.261 ± 1.132
1.223AlaCys: 1.223 ± 0.577
2.446AlaAsp: 2.446 ± 1.038
2.038AlaGlu: 2.038 ± 0.608
2.446AlaPhe: 2.446 ± 0.519
2.854AlaGly: 2.854 ± 1.513
1.631AlaHis: 1.631 ± 0.68
2.854AlaIle: 2.854 ± 0.771
6.115AlaLys: 6.115 ± 2.03
4.077AlaLeu: 4.077 ± 1.052
3.669AlaMet: 3.669 ± 1.128
2.038AlaAsn: 2.038 ± 1.096
2.038AlaPro: 2.038 ± 1.033
4.077AlaGln: 4.077 ± 0.791
2.854AlaArg: 2.854 ± 0.582
6.93AlaSer: 6.93 ± 1.087
3.669AlaThr: 3.669 ± 0.494
2.854AlaVal: 2.854 ± 0.769
0.815AlaTrp: 0.815 ± 0.404
2.446AlaTyr: 2.446 ± 0.727
0.0AlaXaa: 0.0 ± 0.0
Cys
2.038CysAla: 2.038 ± 0.524
0.408CysCys: 0.408 ± 0.46
1.223CysAsp: 1.223 ± 0.316
0.815CysGlu: 0.815 ± 0.287
0.0CysPhe: 0.0 ± 0.0
1.223CysGly: 1.223 ± 0.94
1.223CysHis: 1.223 ± 0.559
0.815CysIle: 0.815 ± 0.404
1.631CysLys: 1.631 ± 0.786
0.408CysLeu: 0.408 ± 0.607
0.0CysMet: 0.0 ± 0.423
1.631CysAsn: 1.631 ± 0.396
0.408CysPro: 0.408 ± 0.279
2.038CysGln: 2.038 ± 0.856
0.815CysArg: 0.815 ± 0.404
0.408CysSer: 0.408 ± 0.312
0.0CysThr: 0.0 ± 0.0
0.408CysVal: 0.408 ± 0.279
0.408CysTrp: 0.408 ± 0.312
0.408CysTyr: 0.408 ± 0.312
0.408CysXaa: 0.408 ± 0.312
Asp
3.669AspAla: 3.669 ± 0.987
1.223AspCys: 1.223 ± 0.492
5.3AspAsp: 5.3 ± 1.297
8.153AspGlu: 8.153 ± 1.851
2.446AspPhe: 2.446 ± 1.04
2.038AspGly: 2.038 ± 0.415
1.223AspHis: 1.223 ± 0.705
2.446AspIle: 2.446 ± 0.585
2.446AspLys: 2.446 ± 0.654
6.115AspLeu: 6.115 ± 0.889
0.815AspMet: 0.815 ± 0.404
1.223AspAsn: 1.223 ± 0.727
4.484AspPro: 4.484 ± 0.889
3.261AspGln: 3.261 ± 0.581
1.223AspArg: 1.223 ± 0.861
3.669AspSer: 3.669 ± 0.737
2.854AspThr: 2.854 ± 0.634
2.446AspVal: 2.446 ± 0.561
0.815AspTrp: 0.815 ± 0.623
2.038AspTyr: 2.038 ± 0.654
0.0AspXaa: 0.0 ± 0.0
Glu
2.854GluAla: 2.854 ± 0.795
0.0GluCys: 0.0 ± 0.0
5.707GluAsp: 5.707 ± 0.447
3.261GluGlu: 3.261 ± 1.24
2.446GluPhe: 2.446 ± 0.654
2.038GluGly: 2.038 ± 1.374
0.408GluHis: 0.408 ± 0.279
2.038GluIle: 2.038 ± 0.536
3.261GluLys: 3.261 ± 0.791
4.077GluLeu: 4.077 ± 1.084
0.0GluMet: 0.0 ± 0.0
1.631GluAsn: 1.631 ± 0.396
2.446GluPro: 2.446 ± 0.393
0.815GluGln: 0.815 ± 0.287
2.446GluArg: 2.446 ± 0.861
4.484GluSer: 4.484 ± 1.661
3.261GluThr: 3.261 ± 1.609
5.707GluVal: 5.707 ± 1.859
2.854GluTrp: 2.854 ± 0.917
2.446GluTyr: 2.446 ± 0.519
0.0GluXaa: 0.0 ± 0.0
Phe
2.038PheAla: 2.038 ± 0.396
1.631PheCys: 1.631 ± 0.786
2.038PheAsp: 2.038 ± 0.934
2.446PheGlu: 2.446 ± 1.118
1.223PhePhe: 1.223 ± 0.316
3.669PheGly: 3.669 ± 1.189
1.631PheHis: 1.631 ± 1.053
3.669PheIle: 3.669 ± 0.762
2.038PheLys: 2.038 ± 0.788
2.854PheLeu: 2.854 ± 1.697
1.631PheMet: 1.631 ± 0.763
3.669PheAsn: 3.669 ± 0.823
1.631PhePro: 1.631 ± 0.969
3.669PheGln: 3.669 ± 0.858
1.223PheArg: 1.223 ± 0.838
4.077PheSer: 4.077 ± 1.221
2.446PheThr: 2.446 ± 1.424
4.484PheVal: 4.484 ± 1.053
0.815PheTrp: 0.815 ± 0.501
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
3.669GlyAla: 3.669 ± 1.467
0.408GlyCys: 0.408 ± 0.312
3.261GlyAsp: 3.261 ± 0.928
4.077GlyGlu: 4.077 ± 0.924
5.707GlyPhe: 5.707 ± 1.404
6.523GlyGly: 6.523 ± 2.441
1.631GlyHis: 1.631 ± 0.639
2.446GlyIle: 2.446 ± 1.0
7.746GlyLys: 7.746 ± 2.616
3.261GlyLeu: 3.261 ± 1.031
1.223GlyMet: 1.223 ± 0.691
4.484GlyAsn: 4.484 ± 1.851
4.892GlyPro: 4.892 ± 1.508
2.854GlyGln: 2.854 ± 0.413
4.892GlyArg: 4.892 ± 1.293
4.484GlySer: 4.484 ± 2.838
1.631GlyThr: 1.631 ± 1.126
2.446GlyVal: 2.446 ± 1.258
0.0GlyTrp: 0.0 ± 0.0
1.631GlyTyr: 1.631 ± 0.574
0.0GlyXaa: 0.0 ± 0.0
His
2.446HisAla: 2.446 ± 1.302
0.0HisCys: 0.0 ± 0.0
1.631HisAsp: 1.631 ± 0.807
0.815HisGlu: 0.815 ± 0.501
0.408HisPhe: 0.408 ± 0.601
0.408HisGly: 0.408 ± 0.279
1.631HisHis: 1.631 ± 0.481
0.0HisIle: 0.0 ± 0.0
0.408HisLys: 0.408 ± 0.312
1.631HisLeu: 1.631 ± 0.488
0.0HisMet: 0.0 ± 0.0
2.446HisAsn: 2.446 ± 0.859
1.223HisPro: 1.223 ± 0.369
0.0HisGln: 0.0 ± 0.0
0.408HisArg: 0.408 ± 0.279
4.077HisSer: 4.077 ± 0.856
0.408HisThr: 0.408 ± 0.312
1.223HisVal: 1.223 ± 0.559
0.815HisTrp: 0.815 ± 0.519
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.261IleAla: 3.261 ± 1.26
1.223IleCys: 1.223 ± 0.473
2.854IleAsp: 2.854 ± 0.71
1.631IleGlu: 1.631 ± 0.538
2.038IlePhe: 2.038 ± 0.8
2.854IleGly: 2.854 ± 0.633
1.223IleHis: 1.223 ± 0.559
3.261IleIle: 3.261 ± 0.906
2.446IleLys: 2.446 ± 0.882
5.707IleLeu: 5.707 ± 1.272
2.038IleMet: 2.038 ± 0.586
2.854IleAsn: 2.854 ± 0.636
2.038IlePro: 2.038 ± 0.974
2.038IleGln: 2.038 ± 0.415
1.223IleArg: 1.223 ± 0.316
5.3IleSer: 5.3 ± 1.506
1.631IleThr: 1.631 ± 0.819
3.669IleVal: 3.669 ± 1.011
0.0IleTrp: 0.0 ± 0.0
1.223IleTyr: 1.223 ± 0.559
0.0IleXaa: 0.0 ± 0.0
Lys
2.854LysAla: 2.854 ± 0.917
0.0LysCys: 0.0 ± 0.0
4.077LysAsp: 4.077 ± 1.466
3.261LysGlu: 3.261 ± 1.22
6.523LysPhe: 6.523 ± 1.676
9.376LysGly: 9.376 ± 2.956
0.408LysHis: 0.408 ± 0.279
1.631LysIle: 1.631 ± 0.538
6.115LysLys: 6.115 ± 1.816
5.3LysLeu: 5.3 ± 1.373
0.815LysMet: 0.815 ± 0.558
1.223LysAsn: 1.223 ± 0.705
1.223LysPro: 1.223 ± 0.515
2.854LysGln: 2.854 ± 0.634
3.261LysArg: 3.261 ± 0.943
5.3LysSer: 5.3 ± 1.819
2.038LysThr: 2.038 ± 0.707
6.93LysVal: 6.93 ± 2.082
2.038LysTrp: 2.038 ± 0.608
2.038LysTyr: 2.038 ± 0.536
0.0LysXaa: 0.0 ± 0.0
Leu
6.523LeuAla: 6.523 ± 1.861
2.854LeuCys: 2.854 ± 0.746
4.892LeuAsp: 4.892 ± 1.104
4.484LeuGlu: 4.484 ± 0.916
2.038LeuPhe: 2.038 ± 0.442
4.892LeuGly: 4.892 ± 0.705
0.408LeuHis: 0.408 ± 0.279
3.261LeuIle: 3.261 ± 1.117
8.153LeuLys: 8.153 ± 1.494
4.892LeuLeu: 4.892 ± 1.484
2.038LeuMet: 2.038 ± 0.886
3.669LeuAsn: 3.669 ± 0.404
5.3LeuPro: 5.3 ± 1.236
4.077LeuGln: 4.077 ± 1.122
4.892LeuArg: 4.892 ± 0.387
6.523LeuSer: 6.523 ± 2.096
1.223LeuThr: 1.223 ± 0.676
4.892LeuVal: 4.892 ± 1.847
1.223LeuTrp: 1.223 ± 0.791
2.446LeuTyr: 2.446 ± 0.882
0.0LeuXaa: 0.0 ± 0.0
Met
1.223MetAla: 1.223 ± 0.515
1.223MetCys: 1.223 ± 0.559
2.446MetAsp: 2.446 ± 0.815
2.446MetGlu: 2.446 ± 0.561
0.815MetPhe: 0.815 ± 0.287
0.815MetGly: 0.815 ± 0.563
0.815MetHis: 0.815 ± 0.558
0.815MetIle: 0.815 ± 0.519
2.854MetLys: 2.854 ± 0.659
1.631MetLeu: 1.631 ± 0.786
0.815MetMet: 0.815 ± 0.512
0.0MetAsn: 0.0 ± 0.0
0.815MetPro: 0.815 ± 0.501
1.223MetGln: 1.223 ± 0.578
2.446MetArg: 2.446 ± 1.001
1.631MetSer: 1.631 ± 0.555
1.631MetThr: 1.631 ± 0.725
4.484MetVal: 4.484 ± 1.375
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
4.484AsnAla: 4.484 ± 1.006
0.815AsnCys: 0.815 ± 0.404
2.038AsnAsp: 2.038 ± 1.123
0.408AsnGlu: 0.408 ± 0.279
2.446AsnPhe: 2.446 ± 1.0
4.077AsnGly: 4.077 ± 1.525
0.0AsnHis: 0.0 ± 0.0
2.038AsnIle: 2.038 ± 0.891
2.854AsnLys: 2.854 ± 0.851
4.077AsnLeu: 4.077 ± 1.303
0.408AsnMet: 0.408 ± 0.279
1.631AsnAsn: 1.631 ± 0.693
0.815AsnPro: 0.815 ± 0.287
0.408AsnGln: 0.408 ± 0.581
3.669AsnArg: 3.669 ± 0.892
5.3AsnSer: 5.3 ± 1.883
1.223AsnThr: 1.223 ± 0.559
5.3AsnVal: 5.3 ± 0.939
0.815AsnTrp: 0.815 ± 0.623
1.223AsnTyr: 1.223 ± 0.53
0.0AsnXaa: 0.0 ± 0.0
Pro
2.038ProAla: 2.038 ± 1.002
0.815ProCys: 0.815 ± 0.501
3.669ProAsp: 3.669 ± 0.565
2.446ProGlu: 2.446 ± 0.747
0.408ProPhe: 0.408 ± 0.279
1.631ProGly: 1.631 ± 0.947
0.408ProHis: 0.408 ± 0.46
4.892ProIle: 4.892 ± 0.94
0.815ProLys: 0.815 ± 0.404
4.077ProLeu: 4.077 ± 0.705
2.446ProMet: 2.446 ± 0.654
1.631ProAsn: 1.631 ± 0.538
7.338ProPro: 7.338 ± 3.154
3.261ProGln: 3.261 ± 0.594
2.854ProArg: 2.854 ± 0.949
4.077ProSer: 4.077 ± 1.849
4.892ProThr: 4.892 ± 1.47
5.707ProVal: 5.707 ± 0.696
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
2.854GlnAla: 2.854 ± 1.385
1.223GlnCys: 1.223 ± 0.559
1.631GlnAsp: 1.631 ± 0.481
2.038GlnGlu: 2.038 ± 0.415
3.261GlnPhe: 3.261 ± 0.651
2.854GlnGly: 2.854 ± 0.689
1.223GlnHis: 1.223 ± 0.559
2.446GlnIle: 2.446 ± 0.596
2.854GlnLys: 2.854 ± 1.027
2.854GlnLeu: 2.854 ± 0.576
1.223GlnMet: 1.223 ± 1.156
4.077GlnAsn: 4.077 ± 0.895
2.038GlnPro: 2.038 ± 0.538
1.223GlnGln: 1.223 ± 0.316
2.038GlnArg: 2.038 ± 0.442
2.854GlnSer: 2.854 ± 0.822
2.854GlnThr: 2.854 ± 0.413
5.3GlnVal: 5.3 ± 1.064
0.408GlnTrp: 0.408 ± 0.581
1.223GlnTyr: 1.223 ± 0.369
0.0GlnXaa: 0.0 ± 0.0
Arg
4.892ArgAla: 4.892 ± 1.086
1.223ArgCys: 1.223 ± 0.669
2.854ArgAsp: 2.854 ± 0.659
2.446ArgGlu: 2.446 ± 1.13
3.261ArgPhe: 3.261 ± 0.515
4.077ArgGly: 4.077 ± 1.747
0.815ArgHis: 0.815 ± 0.404
1.631ArgIle: 1.631 ± 1.053
2.446ArgLys: 2.446 ± 0.654
6.93ArgLeu: 6.93 ± 2.125
2.446ArgMet: 2.446 ± 0.902
0.815ArgAsn: 0.815 ± 0.287
2.446ArgPro: 2.446 ± 0.535
1.631ArgGln: 1.631 ± 1.05
6.115ArgArg: 6.115 ± 1.671
2.854ArgSer: 2.854 ± 0.776
3.669ArgThr: 3.669 ± 1.561
2.854ArgVal: 2.854 ± 0.74
0.408ArgTrp: 0.408 ± 0.607
1.631ArgTyr: 1.631 ± 0.786
0.0ArgXaa: 0.0 ± 0.0
Ser
4.484SerAla: 4.484 ± 0.893
0.408SerCys: 0.408 ± 0.312
3.669SerAsp: 3.669 ± 0.872
2.038SerGlu: 2.038 ± 0.488
5.707SerPhe: 5.707 ± 1.708
9.376SerGly: 9.376 ± 2.88
0.815SerHis: 0.815 ± 0.558
5.707SerIle: 5.707 ± 1.199
2.038SerLys: 2.038 ± 0.612
6.115SerLeu: 6.115 ± 3.246
3.669SerMet: 3.669 ± 1.008
2.854SerAsn: 2.854 ± 0.988
4.892SerPro: 4.892 ± 1.443
4.077SerGln: 4.077 ± 1.146
7.746SerArg: 7.746 ± 3.174
6.93SerSer: 6.93 ± 2.446
4.892SerThr: 4.892 ± 2.447
4.077SerVal: 4.077 ± 1.205
1.631SerTrp: 1.631 ± 0.983
4.077SerTyr: 4.077 ± 0.853
0.0SerXaa: 0.0 ± 0.0
Thr
1.631ThrAla: 1.631 ± 0.555
0.408ThrCys: 0.408 ± 0.46
2.854ThrAsp: 2.854 ± 0.869
2.446ThrGlu: 2.446 ± 0.679
0.815ThrPhe: 0.815 ± 0.615
2.854ThrGly: 2.854 ± 0.529
0.815ThrHis: 0.815 ± 0.623
2.038ThrIle: 2.038 ± 0.654
2.854ThrLys: 2.854 ± 0.918
3.261ThrLeu: 3.261 ± 0.929
2.038ThrMet: 2.038 ± 0.601
2.038ThrAsn: 2.038 ± 0.834
3.261ThrPro: 3.261 ± 1.449
1.631ThrGln: 1.631 ± 0.829
2.854ThrArg: 2.854 ± 1.837
6.115ThrSer: 6.115 ± 2.585
4.484ThrThr: 4.484 ± 1.316
4.484ThrVal: 4.484 ± 0.808
0.408ThrTrp: 0.408 ± 0.601
0.815ThrTyr: 0.815 ± 0.563
0.0ThrXaa: 0.0 ± 0.0
Val
3.261ValAla: 3.261 ± 0.515
2.038ValCys: 2.038 ± 0.707
4.892ValAsp: 4.892 ± 0.493
6.115ValGlu: 6.115 ± 2.491
2.854ValPhe: 2.854 ± 1.335
3.261ValGly: 3.261 ± 0.861
1.223ValHis: 1.223 ± 0.559
4.077ValIle: 4.077 ± 0.738
6.523ValLys: 6.523 ± 1.152
5.3ValLeu: 5.3 ± 0.601
2.446ValMet: 2.446 ± 0.632
3.261ValAsn: 3.261 ± 1.27
4.892ValPro: 4.892 ± 1.062
5.3ValGln: 5.3 ± 0.947
2.446ValArg: 2.446 ± 1.072
7.746ValSer: 7.746 ± 1.14
3.261ValThr: 3.261 ± 0.799
10.192ValVal: 10.192 ± 2.235
0.0ValTrp: 0.0 ± 0.0
2.854ValTyr: 2.854 ± 0.71
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.815TrpGlu: 0.815 ± 0.404
0.815TrpPhe: 0.815 ± 0.606
0.408TrpGly: 0.408 ± 0.279
1.223TrpHis: 1.223 ± 0.369
0.815TrpIle: 0.815 ± 1.213
0.815TrpLys: 0.815 ± 0.287
3.261TrpLeu: 3.261 ± 0.893
0.0TrpMet: 0.0 ± 0.0
0.815TrpAsn: 0.815 ± 0.623
0.815TrpPro: 0.815 ± 0.404
0.815TrpGln: 0.815 ± 0.287
0.815TrpArg: 0.815 ± 0.623
0.408TrpSer: 0.408 ± 0.581
0.408TrpThr: 0.408 ± 0.581
0.815TrpVal: 0.815 ± 0.404
0.0TrpTrp: 0.0 ± 0.0
0.815TrpTyr: 0.815 ± 0.623
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.854TyrAla: 2.854 ± 0.634
0.0TyrCys: 0.0 ± 0.0
0.408TyrAsp: 0.408 ± 0.279
0.0TyrGlu: 0.0 ± 0.0
1.223TyrPhe: 1.223 ± 0.838
2.038TyrGly: 2.038 ± 0.608
1.223TyrHis: 1.223 ± 0.559
1.631TyrIle: 1.631 ± 0.722
2.854TyrLys: 2.854 ± 0.71
2.854TyrLeu: 2.854 ± 1.326
0.0TyrMet: 0.0 ± 0.0
2.038TyrAsn: 2.038 ± 0.598
0.408TyrPro: 0.408 ± 0.581
1.223TyrGln: 1.223 ± 0.53
1.223TyrArg: 1.223 ± 0.473
2.038TyrSer: 2.038 ± 0.646
1.631TyrThr: 1.631 ± 0.819
3.261TyrVal: 3.261 ± 0.723
0.408TyrTrp: 0.408 ± 0.279
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.408XaaVal: 0.408 ± 0.312
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (2454 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski