Amino acid dipepetide frequency for Slackia equolifaciens

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.471AlaAla: 15.471 ± 0.247	2.436AlaCys: 2.436 ± 0.067	6.48AlaAsp: 6.48 ± 0.086	7.245AlaGlu: 7.245 ± 0.126	4.73AlaPhe: 4.73 ± 0.084	9.266AlaGly: 9.266 ± 0.139	2.325AlaHis: 2.325 ± 0.065	6.177AlaIle: 6.177 ± 0.099	4.43AlaLys: 4.43 ± 0.092	11.248AlaLeu: 11.248 ± 0.171	3.249AlaMet: 3.249 ± 0.071	3.109AlaAsn: 3.109 ± 0.069	4.59AlaPro: 4.59 ± 0.103	4.378AlaGln: 4.378 ± 0.098	6.798AlaArg: 6.798 ± 0.132	7.6AlaSer: 7.6 ± 0.126	5.554AlaThr: 5.554 ± 0.119	8.773AlaVal: 8.773 ± 0.132	1.243AlaTrp: 1.243 ± 0.044	3.063AlaTyr: 3.063 ± 0.069	0.0AlaXaa: 0.0 ± 0.0
Cys	1.989CysAla: 1.989 ± 0.052	0.319CysCys: 0.319 ± 0.023	1.15CysAsp: 1.15 ± 0.041	1.058CysGlu: 1.058 ± 0.04	0.578CysPhe: 0.578 ± 0.027	1.792CysGly: 1.792 ± 0.052	0.327CysHis: 0.327 ± 0.025	0.963CysIle: 0.963 ± 0.037	0.51CysLys: 0.51 ± 0.029	1.31CysLeu: 1.31 ± 0.048	0.493CysMet: 0.493 ± 0.024	0.394CysAsn: 0.394 ± 0.023	0.833CysPro: 0.833 ± 0.036	0.382CysGln: 0.382 ± 0.025	0.86CysArg: 0.86 ± 0.038	0.897CysSer: 0.897 ± 0.041	0.843CysThr: 0.843 ± 0.036	1.423CysVal: 1.423 ± 0.052	0.145CysTrp: 0.145 ± 0.013	0.404CysTyr: 0.404 ± 0.02	0.0CysXaa: 0.0 ± 0.0
Asp	8.546AspAla: 8.546 ± 0.131	0.829AspCys: 0.829 ± 0.041	3.734AspAsp: 3.734 ± 0.083	5.285AspGlu: 5.285 ± 0.1	2.465AspPhe: 2.465 ± 0.065	5.303AspGly: 5.303 ± 0.108	0.866AspHis: 0.866 ± 0.038	3.231AspIle: 3.231 ± 0.072	1.89AspLys: 1.89 ± 0.061	4.956AspLeu: 4.956 ± 0.095	1.761AspMet: 1.761 ± 0.048	1.547AspAsn: 1.547 ± 0.065	2.841AspPro: 2.841 ± 0.071	1.336AspGln: 1.336 ± 0.046	2.943AspArg: 2.943 ± 0.063	3.33AspSer: 3.33 ± 0.074	2.673AspThr: 2.673 ± 0.061	4.715AspVal: 4.715 ± 0.084	0.649AspTrp: 0.649 ± 0.031	1.912AspTyr: 1.912 ± 0.054	0.0AspXaa: 0.0 ± 0.0
Glu	7.956GluAla: 7.956 ± 0.13	0.886GluCys: 0.886 ± 0.036	3.694GluAsp: 3.694 ± 0.072	5.299GluGlu: 5.299 ± 0.108	2.348GluPhe: 2.348 ± 0.059	5.864GluGly: 5.864 ± 0.1	1.434GluHis: 1.434 ± 0.051	3.098GluIle: 3.098 ± 0.084	2.837GluLys: 2.837 ± 0.083	6.067GluLeu: 6.067 ± 0.111	1.804GluMet: 1.804 ± 0.054	2.24GluAsn: 2.24 ± 0.054	2.58GluPro: 2.58 ± 0.074	2.292GluGln: 2.292 ± 0.059	4.968GluArg: 4.968 ± 0.094	3.906GluSer: 3.906 ± 0.079	3.153GluThr: 3.153 ± 0.074	4.532GluVal: 4.532 ± 0.086	0.695GluTrp: 0.695 ± 0.031	1.92GluTyr: 1.92 ± 0.058	0.0GluXaa: 0.0 ± 0.0
Phe	4.549PheAla: 4.549 ± 0.094	0.734PheCys: 0.734 ± 0.035	2.942PheAsp: 2.942 ± 0.064	2.585PheGlu: 2.585 ± 0.058	1.546PhePhe: 1.546 ± 0.056	3.731PheGly: 3.731 ± 0.077	0.561PheHis: 0.561 ± 0.024	1.982PheIle: 1.982 ± 0.058	1.332PheLys: 1.332 ± 0.046	3.138PheLeu: 3.138 ± 0.077	1.073PheMet: 1.073 ± 0.044	1.122PheAsn: 1.122 ± 0.036	1.36PhePro: 1.36 ± 0.048	0.859PheGln: 0.859 ± 0.035	1.612PheArg: 1.612 ± 0.049	2.533PheSer: 2.533 ± 0.059	2.003PheThr: 2.003 ± 0.078	3.234PheVal: 3.234 ± 0.082	0.436PheTrp: 0.436 ± 0.025	1.136PheTyr: 1.136 ± 0.042	0.0PheXaa: 0.0 ± 0.0
Gly	9.134GlyAla: 9.134 ± 0.137	1.612GlyCys: 1.612 ± 0.044	4.68GlyAsp: 4.68 ± 0.089	5.225GlyGlu: 5.225 ± 0.087	3.55GlyPhe: 3.55 ± 0.065	6.802GlyGly: 6.802 ± 0.135	1.482GlyHis: 1.482 ± 0.047	5.272GlyIle: 5.272 ± 0.088	3.703GlyLys: 3.703 ± 0.085	6.947GlyLeu: 6.947 ± 0.098	2.681GlyMet: 2.681 ± 0.064	2.495GlyAsn: 2.495 ± 0.07	2.147GlyPro: 2.147 ± 0.057	2.335GlyGln: 2.335 ± 0.056	4.579GlyArg: 4.579 ± 0.098	5.224GlySer: 5.224 ± 0.104	4.521GlyThr: 4.521 ± 0.096	7.106GlyVal: 7.106 ± 0.119	0.992GlyTrp: 0.992 ± 0.042	2.671GlyTyr: 2.671 ± 0.068	0.0GlyXaa: 0.0 ± 0.0
His	2.297HisAla: 2.297 ± 0.059	0.329HisCys: 0.329 ± 0.021	1.252HisAsp: 1.252 ± 0.044	1.298HisGlu: 1.298 ± 0.05	0.671HisPhe: 0.671 ± 0.03	1.591HisGly: 1.591 ± 0.046	0.415HisHis: 0.415 ± 0.028	0.991HisIle: 0.991 ± 0.04	0.536HisLys: 0.536 ± 0.027	1.507HisLeu: 1.507 ± 0.046	0.536HisMet: 0.536 ± 0.028	0.533HisAsn: 0.533 ± 0.028	1.066HisPro: 1.066 ± 0.042	0.447HisGln: 0.447 ± 0.025	1.017HisArg: 1.017 ± 0.041	0.984HisSer: 0.984 ± 0.041	0.864HisThr: 0.864 ± 0.036	1.5HisVal: 1.5 ± 0.05	0.198HisTrp: 0.198 ± 0.017	0.576HisTyr: 0.576 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	7.021IleAla: 7.021 ± 0.114	0.864IleCys: 0.864 ± 0.036	3.804IleAsp: 3.804 ± 0.072	4.022IleGlu: 4.022 ± 0.076	1.509IlePhe: 1.509 ± 0.047	4.253IleGly: 4.253 ± 0.088	0.821IleHis: 0.821 ± 0.035	2.631IleIle: 2.631 ± 0.074	1.889IleLys: 1.889 ± 0.054	3.945IleLeu: 3.945 ± 0.079	1.368IleMet: 1.368 ± 0.045	1.505IleAsn: 1.505 ± 0.049	2.604IlePro: 2.604 ± 0.074	1.399IleGln: 1.399 ± 0.047	2.446IleArg: 2.446 ± 0.064	3.138IleSer: 3.138 ± 0.068	2.782IleThr: 2.782 ± 0.063	4.746IleVal: 4.746 ± 0.098	0.501IleTrp: 0.501 ± 0.025	1.283IleTyr: 1.283 ± 0.042	0.0IleXaa: 0.0 ± 0.0
Lys	4.185LysAla: 4.185 ± 0.089	0.498LysCys: 0.498 ± 0.031	2.108LysAsp: 2.108 ± 0.066	2.481LysGlu: 2.481 ± 0.073	1.089LysPhe: 1.089 ± 0.042	2.889LysGly: 2.889 ± 0.065	0.755LysHis: 0.755 ± 0.033	1.717LysIle: 1.717 ± 0.051	2.083LysLys: 2.083 ± 0.072	3.138LysLeu: 3.138 ± 0.069	1.085LysMet: 1.085 ± 0.044	1.344LysAsn: 1.344 ± 0.043	1.741LysPro: 1.741 ± 0.063	1.21LysGln: 1.21 ± 0.042	2.918LysArg: 2.918 ± 0.074	2.177LysSer: 2.177 ± 0.064	2.345LysThr: 2.345 ± 0.056	2.736LysVal: 2.736 ± 0.07	0.345LysTrp: 0.345 ± 0.022	1.003LysTyr: 1.003 ± 0.039	0.0LysXaa: 0.0 ± 0.0
Leu	10.908LeuAla: 10.908 ± 0.155	1.478LeuCys: 1.478 ± 0.047	5.601LeuAsp: 5.601 ± 0.093	5.567LeuGlu: 5.567 ± 0.102	3.612LeuPhe: 3.612 ± 0.094	7.34LeuGly: 7.34 ± 0.115	1.515LeuHis: 1.515 ± 0.052	4.415LeuIle: 4.415 ± 0.085	3.171LeuLys: 3.171 ± 0.061	7.754LeuLeu: 7.754 ± 0.162	2.359LeuMet: 2.359 ± 0.06	2.308LeuAsn: 2.308 ± 0.057	4.007LeuPro: 4.007 ± 0.085	2.137LeuGln: 2.137 ± 0.057	5.027LeuArg: 5.027 ± 0.09	5.943LeuSer: 5.943 ± 0.099	4.459LeuThr: 4.459 ± 0.081	7.012LeuVal: 7.012 ± 0.117	0.866LeuTrp: 0.866 ± 0.037	2.358LeuTyr: 2.358 ± 0.061	0.0LeuXaa: 0.0 ± 0.0
Met	3.214MetAla: 3.214 ± 0.067	0.389MetCys: 0.389 ± 0.024	1.542MetAsp: 1.542 ± 0.048	1.686MetGlu: 1.686 ± 0.053	0.916MetPhe: 0.916 ± 0.039	2.511MetGly: 2.511 ± 0.064	0.564MetHis: 0.564 ± 0.029	1.146MetIle: 1.146 ± 0.043	1.212MetLys: 1.212 ± 0.04	2.654MetLeu: 2.654 ± 0.058	0.813MetMet: 0.813 ± 0.034	0.955MetAsn: 0.955 ± 0.039	1.544MetPro: 1.544 ± 0.049	0.948MetGln: 0.948 ± 0.037	1.937MetArg: 1.937 ± 0.058	1.777MetSer: 1.777 ± 0.049	1.616MetThr: 1.616 ± 0.051	1.892MetVal: 1.892 ± 0.049	0.273MetTrp: 0.273 ± 0.019	0.626MetTyr: 0.626 ± 0.026	0.0MetXaa: 0.0 ± 0.0
Asn	3.554AsnAla: 3.554 ± 0.074	0.42AsnCys: 0.42 ± 0.025	1.752AsnAsp: 1.752 ± 0.056	1.963AsnGlu: 1.963 ± 0.058	0.917AsnPhe: 0.917 ± 0.035	2.472AsnGly: 2.472 ± 0.078	0.552AsnHis: 0.552 ± 0.029	1.451AsnIle: 1.451 ± 0.051	0.941AsnLys: 0.941 ± 0.038	2.441AsnLeu: 2.441 ± 0.059	0.827AsnMet: 0.827 ± 0.034	0.891AsnAsn: 0.891 ± 0.053	2.006AsnPro: 2.006 ± 0.049	0.844AsnGln: 0.844 ± 0.036	1.66AsnArg: 1.66 ± 0.049	1.542AsnSer: 1.542 ± 0.049	1.519AsnThr: 1.519 ± 0.061	2.388AsnVal: 2.388 ± 0.057	0.299AsnTrp: 0.299 ± 0.019	0.897AsnTyr: 0.897 ± 0.036	0.0AsnXaa: 0.0 ± 0.0
Pro	4.727ProAla: 4.727 ± 0.104	0.625ProCys: 0.625 ± 0.032	3.021ProAsp: 3.021 ± 0.064	3.487ProGlu: 3.487 ± 0.073	1.792ProPhe: 1.792 ± 0.048	3.219ProGly: 3.219 ± 0.075	0.924ProHis: 0.924 ± 0.038	2.096ProIle: 2.096 ± 0.058	1.555ProLys: 1.555 ± 0.051	3.693ProLeu: 3.693 ± 0.084	0.994ProMet: 0.994 ± 0.04	1.248ProAsn: 1.248 ± 0.041	1.231ProPro: 1.231 ± 0.048	1.546ProGln: 1.546 ± 0.05	2.185ProArg: 2.185 ± 0.066	2.717ProSer: 2.717 ± 0.064	2.25ProThr: 2.25 ± 0.063	3.362ProVal: 3.362 ± 0.067	0.44ProTrp: 0.44 ± 0.026	1.422ProTyr: 1.422 ± 0.045	0.0ProXaa: 0.0 ± 0.0
Gln	3.659GlnAla: 3.659 ± 0.084	0.353GlnCys: 0.353 ± 0.023	1.555GlnAsp: 1.555 ± 0.045	2.016GlnGlu: 2.016 ± 0.057	0.967GlnPhe: 0.967 ± 0.036	2.558GlnGly: 2.558 ± 0.072	0.544GlnHis: 0.544 ± 0.028	1.529GlnIle: 1.529 ± 0.044	1.185GlnLys: 1.185 ± 0.042	2.51GlnLeu: 2.51 ± 0.072	0.952GlnMet: 0.952 ± 0.037	0.925GlnAsn: 0.925 ± 0.035	1.4GlnPro: 1.4 ± 0.065	1.212GlnGln: 1.212 ± 0.046	1.904GlnArg: 1.904 ± 0.053	1.618GlnSer: 1.618 ± 0.046	1.579GlnThr: 1.579 ± 0.054	2.22GlnVal: 2.22 ± 0.061	0.346GlnTrp: 0.346 ± 0.023	0.782GlnTyr: 0.782 ± 0.035	0.0GlnXaa: 0.0 ± 0.0
Arg	6.302ArgAla: 6.302 ± 0.114	0.831ArgCys: 0.831 ± 0.033	3.44ArgAsp: 3.44 ± 0.064	4.395ArgGlu: 4.395 ± 0.09	2.345ArgPhe: 2.345 ± 0.058	4.17ArgGly: 4.17 ± 0.087	1.144ArgHis: 1.144 ± 0.042	3.622ArgIle: 3.622 ± 0.074	2.475ArgLys: 2.475 ± 0.065	5.111ArgLeu: 5.111 ± 0.106	2.024ArgMet: 2.024 ± 0.06	1.652ArgAsn: 1.652 ± 0.047	2.246ArgPro: 2.246 ± 0.066	1.657ArgGln: 1.657 ± 0.058	4.378ArgArg: 4.378 ± 0.104	3.192ArgSer: 3.192 ± 0.081	2.893ArgThr: 2.893 ± 0.071	4.226ArgVal: 4.226 ± 0.086	0.578ArgTrp: 0.578 ± 0.03	1.804ArgTyr: 1.804 ± 0.052	0.0ArgXaa: 0.0 ± 0.0
Ser	6.44SerAla: 6.44 ± 0.1	0.992SerCys: 0.992 ± 0.045	3.665SerAsp: 3.665 ± 0.082	3.564SerGlu: 3.564 ± 0.078	2.5SerPhe: 2.5 ± 0.061	5.61SerGly: 5.61 ± 0.105	1.154SerHis: 1.154 ± 0.037	3.394SerIle: 3.394 ± 0.078	2.217SerLys: 2.217 ± 0.06	5.408SerLeu: 5.408 ± 0.105	1.726SerMet: 1.726 ± 0.047	1.873SerAsn: 1.873 ± 0.052	2.516SerPro: 2.516 ± 0.063	1.925SerGln: 1.925 ± 0.055	3.482SerArg: 3.482 ± 0.074	4.389SerSer: 4.389 ± 0.112	3.109SerThr: 3.109 ± 0.077	4.512SerVal: 4.512 ± 0.069	0.712SerTrp: 0.712 ± 0.032	1.853SerTyr: 1.853 ± 0.05	0.0SerXaa: 0.0 ± 0.0
Thr	5.065ThrAla: 5.065 ± 0.101	0.879ThrCys: 0.879 ± 0.036	2.873ThrAsp: 2.873 ± 0.071	2.774ThrGlu: 2.774 ± 0.07	2.077ThrPhe: 2.077 ± 0.07	4.654ThrGly: 4.654 ± 0.091	1.096ThrHis: 1.096 ± 0.038	2.772ThrIle: 2.772 ± 0.081	1.789ThrLys: 1.789 ± 0.051	4.976ThrLeu: 4.976 ± 0.096	1.344ThrMet: 1.344 ± 0.045	1.476ThrAsn: 1.476 ± 0.061	2.78ThrPro: 2.78 ± 0.072	1.606ThrGln: 1.606 ± 0.047	2.538ThrArg: 2.538 ± 0.056	2.982ThrSer: 2.982 ± 0.07	2.658ThrThr: 2.658 ± 0.076	4.44ThrVal: 4.44 ± 0.109	0.578ThrTrp: 0.578 ± 0.028	1.628ThrTyr: 1.628 ± 0.066	0.0ThrXaa: 0.0 ± 0.0
Val	8.952ValAla: 8.952 ± 0.139	1.489ValCys: 1.489 ± 0.042	4.859ValAsp: 4.859 ± 0.085	5.054ValGlu: 5.054 ± 0.086	3.218ValPhe: 3.218 ± 0.086	5.798ValGly: 5.798 ± 0.091	1.387ValHis: 1.387 ± 0.039	4.136ValIle: 4.136 ± 0.077	2.798ValLys: 2.798 ± 0.066	7.301ValLeu: 7.301 ± 0.119	2.064ValMet: 2.064 ± 0.055	2.444ValAsn: 2.444 ± 0.062	3.417ValPro: 3.417 ± 0.062	2.119ValGln: 2.119 ± 0.047	4.737ValArg: 4.737 ± 0.092	4.968ValSer: 4.968 ± 0.093	4.162ValThr: 4.162 ± 0.116	6.832ValVal: 6.832 ± 0.127	0.806ValTrp: 0.806 ± 0.031	2.112ValTyr: 2.112 ± 0.055	0.0ValXaa: 0.0 ± 0.0
Trp	1.054TrpAla: 1.054 ± 0.041	0.201TrpCys: 0.201 ± 0.019	0.595TrpAsp: 0.595 ± 0.03	0.635TrpGlu: 0.635 ± 0.029	0.458TrpPhe: 0.458 ± 0.028	0.866TrpGly: 0.866 ± 0.034	0.246TrpHis: 0.246 ± 0.018	0.598TrpIle: 0.598 ± 0.028	0.385TrpLys: 0.385 ± 0.024	1.034TrpLeu: 1.034 ± 0.037	0.362TrpMet: 0.362 ± 0.023	0.37TrpAsn: 0.37 ± 0.024	0.372TrpPro: 0.372 ± 0.024	0.38TrpGln: 0.38 ± 0.023	0.703TrpArg: 0.703 ± 0.03	0.594TrpSer: 0.594 ± 0.03	0.502TrpThr: 0.502 ± 0.029	0.77TrpVal: 0.77 ± 0.033	0.145TrpTrp: 0.145 ± 0.015	0.284TrpTyr: 0.284 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.14TyrAla: 3.14 ± 0.065	0.508TyrCys: 0.508 ± 0.027	2.064TyrAsp: 2.064 ± 0.048	1.933TyrGlu: 1.933 ± 0.052	1.178TyrPhe: 1.178 ± 0.042	2.469TyrGly: 2.469 ± 0.062	0.494TyrHis: 0.494 ± 0.025	1.31TyrIle: 1.31 ± 0.042	0.912TyrLys: 0.912 ± 0.037	2.698TyrLeu: 2.698 ± 0.064	0.7TyrMet: 0.7 ± 0.031	0.906TyrAsn: 0.906 ± 0.041	1.253TyrPro: 1.253 ± 0.045	0.802TyrGln: 0.802 ± 0.03	1.793TyrArg: 1.793 ± 0.051	1.531TyrSer: 1.531 ± 0.058	1.501TyrThr: 1.501 ± 0.055	2.234TyrVal: 2.234 ± 0.065	0.307TyrTrp: 0.307 ± 0.02	0.976TyrTyr: 0.976 ± 0.039	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2149 proteins (742730 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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