Amino acid dipepetide frequency for Beihai tombus-like virus 13

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.534AlaAla: 5.534 ± 2.06
0.0AlaCys: 0.0 ± 0.0
2.372AlaAsp: 2.372 ± 1.572
2.372AlaGlu: 2.372 ± 1.669
3.162AlaPhe: 3.162 ± 1.276
3.162AlaGly: 3.162 ± 0.592
0.0AlaHis: 0.0 ± 0.0
3.953AlaIle: 3.953 ± 2.166
1.581AlaLys: 1.581 ± 0.709
4.743AlaLeu: 4.743 ± 0.698
1.581AlaMet: 1.581 ± 0.709
4.743AlaAsn: 4.743 ± 1.548
1.581AlaPro: 1.581 ± 0.858
2.372AlaGln: 2.372 ± 0.389
1.581AlaArg: 1.581 ± 1.781
7.115AlaSer: 7.115 ± 2.669
6.324AlaThr: 6.324 ± 2.576
3.162AlaVal: 3.162 ± 1.417
0.791AlaTrp: 0.791 ± 0.53
0.791AlaTyr: 0.791 ± 0.53
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.581CysAsp: 1.581 ± 1.061
0.791CysGlu: 0.791 ± 0.53
0.791CysPhe: 0.791 ± 0.53
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.791CysLys: 0.791 ± 0.53
0.791CysLeu: 0.791 ± 0.53
0.791CysMet: 0.791 ± 0.53
1.581CysAsn: 1.581 ± 1.061
0.791CysPro: 0.791 ± 0.524
0.791CysGln: 0.791 ± 0.53
1.581CysArg: 1.581 ± 0.709
1.581CysSer: 1.581 ± 0.512
0.0CysThr: 0.0 ± 0.0
0.791CysVal: 0.791 ± 0.53
0.0CysTrp: 0.0 ± 0.0
0.791CysTyr: 0.791 ± 0.53
0.0CysXaa: 0.0 ± 0.0
Asp
4.743AspAla: 4.743 ± 1.548
0.791AspCys: 0.791 ± 0.891
2.372AspAsp: 2.372 ± 0.901
2.372AspGlu: 2.372 ± 1.52
0.0AspPhe: 0.0 ± 0.0
1.581AspGly: 1.581 ± 0.709
2.372AspHis: 2.372 ± 1.591
4.743AspIle: 4.743 ± 2.218
0.0AspLys: 0.0 ± 0.0
3.162AspLeu: 3.162 ± 1.387
0.791AspMet: 0.791 ± 0.891
1.581AspAsn: 1.581 ± 1.061
0.791AspPro: 0.791 ± 0.53
1.581AspGln: 1.581 ± 1.061
4.743AspArg: 4.743 ± 2.126
3.953AspSer: 3.953 ± 1.353
0.791AspThr: 0.791 ± 0.53
2.372AspVal: 2.372 ± 1.52
0.0AspTrp: 0.0 ± 0.0
3.953AspTyr: 3.953 ± 1.048
0.0AspXaa: 0.0 ± 0.0
Glu
2.372GluAla: 2.372 ± 0.389
0.791GluCys: 0.791 ± 0.53
3.162GluAsp: 3.162 ± 2.388
3.162GluGlu: 3.162 ± 2.388
2.372GluPhe: 2.372 ± 0.88
1.581GluGly: 1.581 ± 1.048
3.162GluHis: 3.162 ± 1.417
1.581GluIle: 1.581 ± 0.512
5.534GluLys: 5.534 ± 3.713
7.115GluLeu: 7.115 ± 2.069
3.162GluMet: 3.162 ± 2.388
4.743GluAsn: 4.743 ± 1.331
0.0GluPro: 0.0 ± 0.0
1.581GluGln: 1.581 ± 0.709
2.372GluArg: 2.372 ± 2.672
2.372GluSer: 2.372 ± 0.89
2.372GluThr: 2.372 ± 1.52
0.791GluVal: 0.791 ± 0.53
0.0GluTrp: 0.0 ± 0.0
3.162GluTyr: 3.162 ± 1.023
0.0GluXaa: 0.0 ± 0.0
Phe
2.372PheAla: 2.372 ± 1.572
0.791PheCys: 0.791 ± 0.53
2.372PheAsp: 2.372 ± 0.901
4.743PheGlu: 4.743 ± 1.331
0.791PhePhe: 0.791 ± 0.53
3.953PheGly: 3.953 ± 1.87
0.791PheHis: 0.791 ± 0.53
0.791PheIle: 0.791 ± 0.524
0.0PheLys: 0.0 ± 0.0
1.581PheLeu: 1.581 ± 1.061
1.581PheMet: 1.581 ± 0.709
6.324PheAsn: 6.324 ± 1.568
1.581PhePro: 1.581 ± 1.048
0.0PheGln: 0.0 ± 0.0
3.953PheArg: 3.953 ± 1.016
3.162PheSer: 3.162 ± 1.276
3.162PheThr: 3.162 ± 1.387
3.162PheVal: 3.162 ± 0.36
0.0PheTrp: 0.0 ± 0.0
2.372PheTyr: 2.372 ± 1.52
0.0PheXaa: 0.0 ± 0.0
Gly
3.953GlyAla: 3.953 ± 1.87
0.791GlyCys: 0.791 ± 0.53
2.372GlyAsp: 2.372 ± 0.389
3.162GlyGlu: 3.162 ± 0.36
1.581GlyPhe: 1.581 ± 0.512
3.162GlyGly: 3.162 ± 1.387
0.791GlyHis: 0.791 ± 0.53
5.534GlyIle: 5.534 ± 1.043
1.581GlyLys: 1.581 ± 0.512
3.953GlyLeu: 3.953 ± 1.048
0.791GlyMet: 0.791 ± 0.891
3.953GlyAsn: 3.953 ± 1.223
0.791GlyPro: 0.791 ± 0.524
0.0GlyGln: 0.0 ± 0.0
1.581GlyArg: 1.581 ± 0.512
3.953GlySer: 3.953 ± 1.048
4.743GlyThr: 4.743 ± 2.382
2.372GlyVal: 2.372 ± 0.901
0.0GlyTrp: 0.0 ± 0.0
1.581GlyTyr: 1.581 ± 1.061
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
1.581HisAsp: 1.581 ± 1.781
1.581HisGlu: 1.581 ± 1.061
0.791HisPhe: 0.791 ± 0.53
0.791HisGly: 0.791 ± 0.53
0.0HisHis: 0.0 ± 0.0
0.791HisIle: 0.791 ± 0.53
1.581HisLys: 1.581 ± 0.512
0.791HisLeu: 0.791 ± 0.53
0.791HisMet: 0.791 ± 0.891
2.372HisAsn: 2.372 ± 1.52
1.581HisPro: 1.581 ± 1.061
0.0HisGln: 0.0 ± 0.0
0.791HisArg: 0.791 ± 0.53
1.581HisSer: 1.581 ± 1.061
1.581HisThr: 1.581 ± 1.048
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
2.372HisTyr: 2.372 ± 1.591
0.0HisXaa: 0.0 ± 0.0
Ile
3.953IleAla: 3.953 ± 1.353
2.372IleCys: 2.372 ± 0.901
3.162IleAsp: 3.162 ± 0.36
3.162IleGlu: 3.162 ± 2.388
1.581IlePhe: 1.581 ± 0.512
4.743IleGly: 4.743 ± 1.779
0.0IleHis: 0.0 ± 0.0
3.953IleIle: 3.953 ± 1.048
6.324IleLys: 6.324 ± 2.552
5.534IleLeu: 5.534 ± 1.043
0.791IleMet: 0.791 ± 0.53
4.743IleAsn: 4.743 ± 2.056
2.372IlePro: 2.372 ± 1.52
2.372IleGln: 2.372 ± 0.901
4.743IleArg: 4.743 ± 0.779
4.743IleSer: 4.743 ± 1.535
7.115IleThr: 7.115 ± 2.268
4.743IleVal: 4.743 ± 1.383
1.581IleTrp: 1.581 ± 0.709
1.581IleTyr: 1.581 ± 1.048
0.0IleXaa: 0.0 ± 0.0
Lys
3.953LysAla: 3.953 ± 2.5
0.0LysCys: 0.0 ± 0.0
0.791LysAsp: 0.791 ± 0.891
5.534LysGlu: 5.534 ± 0.53
0.791LysPhe: 0.791 ± 0.524
3.953LysGly: 3.953 ± 1.507
0.0LysHis: 0.0 ± 0.0
2.372LysIle: 2.372 ± 1.52
7.905LysLys: 7.905 ± 1.946
4.743LysLeu: 4.743 ± 1.331
0.791LysMet: 0.791 ± 0.53
4.743LysAsn: 4.743 ± 1.001
3.162LysPro: 3.162 ± 1.023
3.162LysGln: 3.162 ± 1.276
3.953LysArg: 3.953 ± 1.734
3.953LysSer: 3.953 ± 1.223
3.953LysThr: 3.953 ± 1.897
4.743LysVal: 4.743 ± 0.779
0.791LysTrp: 0.791 ± 0.53
3.953LysTyr: 3.953 ± 1.734
0.0LysXaa: 0.0 ± 0.0
Leu
5.534LeuAla: 5.534 ± 1.709
0.791LeuCys: 0.791 ± 0.53
3.953LeuAsp: 3.953 ± 0.818
5.534LeuGlu: 5.534 ± 2.939
5.534LeuPhe: 5.534 ± 2.939
5.534LeuGly: 5.534 ± 1.221
2.372LeuHis: 2.372 ± 1.669
2.372LeuIle: 2.372 ± 0.901
2.372LeuLys: 2.372 ± 1.591
10.277LeuLeu: 10.277 ± 4.255
3.162LeuMet: 3.162 ± 0.36
7.115LeuAsn: 7.115 ± 2.268
5.534LeuPro: 5.534 ± 0.53
3.162LeuGln: 3.162 ± 1.276
3.162LeuArg: 3.162 ± 1.417
5.534LeuSer: 5.534 ± 0.854
9.486LeuThr: 9.486 ± 1.058
3.953LeuVal: 3.953 ± 1.223
0.0LeuTrp: 0.0 ± 0.0
2.372LeuTyr: 2.372 ± 0.89
0.0LeuXaa: 0.0 ± 0.0
Met
0.791MetAla: 0.791 ± 0.891
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
2.372MetGlu: 2.372 ± 0.88
1.581MetPhe: 1.581 ± 0.858
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
1.581MetIle: 1.581 ± 1.061
3.953MetLys: 3.953 ± 3.268
0.791MetLeu: 0.791 ± 0.53
0.0MetMet: 0.0 ± 0.0
0.791MetAsn: 0.791 ± 0.891
0.791MetPro: 0.791 ± 0.891
1.581MetGln: 1.581 ± 0.512
1.581MetArg: 1.581 ± 1.061
2.372MetSer: 2.372 ± 0.389
0.0MetThr: 0.0 ± 0.0
3.953MetVal: 3.953 ± 1.734
0.791MetTrp: 0.791 ± 0.524
1.581MetTyr: 1.581 ± 0.858
0.0MetXaa: 0.0 ± 0.0
Asn
4.743AsnAla: 4.743 ± 0.779
0.791AsnCys: 0.791 ± 0.53
1.581AsnAsp: 1.581 ± 1.781
1.581AsnGlu: 1.581 ± 0.512
5.534AsnPhe: 5.534 ± 1.043
3.953AsnGly: 3.953 ± 0.818
1.581AsnHis: 1.581 ± 0.709
7.115AsnIle: 7.115 ± 1.425
1.581AsnLys: 1.581 ± 0.709
7.115AsnLeu: 7.115 ± 1.17
0.791AsnMet: 0.791 ± 0.53
3.953AsnAsn: 3.953 ± 0.818
6.324AsnPro: 6.324 ± 1.072
2.372AsnGln: 2.372 ± 1.109
3.162AsnArg: 3.162 ± 0.36
3.162AsnSer: 3.162 ± 1.368
7.905AsnThr: 7.905 ± 2.053
1.581AsnVal: 1.581 ± 0.858
1.581AsnTrp: 1.581 ± 0.512
2.372AsnTyr: 2.372 ± 0.901
0.0AsnXaa: 0.0 ± 0.0
Pro
3.162ProAla: 3.162 ± 1.276
0.0ProCys: 0.0 ± 0.0
2.372ProAsp: 2.372 ± 1.591
0.791ProGlu: 0.791 ± 0.53
0.791ProPhe: 0.791 ± 0.53
3.162ProGly: 3.162 ± 1.507
0.791ProHis: 0.791 ± 0.53
5.534ProIle: 5.534 ± 0.663
3.953ProLys: 3.953 ± 2.5
3.953ProLeu: 3.953 ± 1.048
2.372ProMet: 2.372 ± 0.901
4.743ProAsn: 4.743 ± 3.144
6.324ProPro: 6.324 ± 0.977
3.953ProGln: 3.953 ± 0.818
0.791ProArg: 0.791 ± 0.53
7.115ProSer: 7.115 ± 1.702
2.372ProThr: 2.372 ± 0.89
3.162ProVal: 3.162 ± 2.388
1.581ProTrp: 1.581 ± 1.048
0.791ProTyr: 0.791 ± 0.53
0.0ProXaa: 0.0 ± 0.0
Gln
1.581GlnAla: 1.581 ± 0.512
0.791GlnCys: 0.791 ± 0.53
0.791GlnAsp: 0.791 ± 0.53
1.581GlnGlu: 1.581 ± 0.709
2.372GlnPhe: 2.372 ± 0.389
0.791GlnGly: 0.791 ± 0.524
0.791GlnHis: 0.791 ± 0.53
5.534GlnIle: 5.534 ± 2.076
0.791GlnLys: 0.791 ± 0.53
4.743GlnLeu: 4.743 ± 0.698
0.791GlnMet: 0.791 ± 0.62
0.0GlnAsn: 0.0 ± 0.0
2.372GlnPro: 2.372 ± 1.572
3.162GlnGln: 3.162 ± 1.507
3.953GlnArg: 3.953 ± 0.818
2.372GlnSer: 2.372 ± 0.901
4.743GlnThr: 4.743 ± 0.529
2.372GlnVal: 2.372 ± 0.389
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.372ArgAla: 2.372 ± 0.389
0.791ArgCys: 0.791 ± 0.53
0.791ArgAsp: 0.791 ± 0.53
3.162ArgGlu: 3.162 ± 2.388
4.743ArgPhe: 4.743 ± 2.056
1.581ArgGly: 1.581 ± 1.061
2.372ArgHis: 2.372 ± 0.901
4.743ArgIle: 4.743 ± 2.126
3.953ArgLys: 3.953 ± 1.016
6.324ArgLeu: 6.324 ± 0.977
0.791ArgMet: 0.791 ± 0.891
1.581ArgAsn: 1.581 ± 1.061
5.534ArgPro: 5.534 ± 2.923
1.581ArgGln: 1.581 ± 1.061
1.581ArgArg: 1.581 ± 0.709
2.372ArgSer: 2.372 ± 0.88
0.791ArgThr: 0.791 ± 0.891
3.162ArgVal: 3.162 ± 0.36
0.0ArgTrp: 0.0 ± 0.0
3.162ArgTyr: 3.162 ± 1.023
0.0ArgXaa: 0.0 ± 0.0
Ser
3.953SerAla: 3.953 ± 1.223
1.581SerCys: 1.581 ± 0.512
3.162SerAsp: 3.162 ± 0.592
0.791SerGlu: 0.791 ± 0.891
3.953SerPhe: 3.953 ± 1.87
2.372SerGly: 2.372 ± 0.88
1.581SerHis: 1.581 ± 1.061
6.324SerIle: 6.324 ± 1.072
3.162SerLys: 3.162 ± 1.368
5.534SerLeu: 5.534 ± 2.923
2.372SerMet: 2.372 ± 0.901
5.534SerAsn: 5.534 ± 2.899
3.162SerPro: 3.162 ± 1.023
2.372SerGln: 2.372 ± 1.572
3.953SerArg: 3.953 ± 2.198
8.696SerSer: 8.696 ± 2.591
7.905SerThr: 7.905 ± 1.527
7.115SerVal: 7.115 ± 1.17
0.791SerTrp: 0.791 ± 0.524
4.743SerTyr: 4.743 ± 1.535
0.0SerXaa: 0.0 ± 0.0
Thr
1.581ThrAla: 1.581 ± 0.512
0.0ThrCys: 0.0 ± 0.0
2.372ThrAsp: 2.372 ± 0.389
2.372ThrGlu: 2.372 ± 0.901
3.953ThrPhe: 3.953 ± 1.366
4.743ThrGly: 4.743 ± 1.779
1.581ThrHis: 1.581 ± 0.512
6.324ThrIle: 6.324 ± 3.014
7.115ThrLys: 7.115 ± 1.238
3.162ThrLeu: 3.162 ± 1.368
0.791ThrMet: 0.791 ± 0.524
3.162ThrAsn: 3.162 ± 2.122
10.277ThrPro: 10.277 ± 1.281
4.743ThrGln: 4.743 ± 3.144
3.953ThrArg: 3.953 ± 1.353
6.324ThrSer: 6.324 ± 1.744
11.858ThrThr: 11.858 ± 6.316
2.372ThrVal: 2.372 ± 0.389
0.0ThrTrp: 0.0 ± 0.0
1.581ThrTyr: 1.581 ± 1.061
0.0ThrXaa: 0.0 ± 0.0
Val
4.743ValAla: 4.743 ± 2.575
0.791ValCys: 0.791 ± 0.53
3.953ValAsp: 3.953 ± 0.184
2.372ValGlu: 2.372 ± 0.88
2.372ValPhe: 2.372 ± 0.901
1.581ValGly: 1.581 ± 0.512
0.0ValHis: 0.0 ± 0.0
3.953ValIle: 3.953 ± 0.818
5.534ValLys: 5.534 ± 0.53
7.115ValLeu: 7.115 ± 3.59
0.0ValMet: 0.0 ± 0.0
3.953ValAsn: 3.953 ± 0.818
3.162ValPro: 3.162 ± 0.36
1.581ValGln: 1.581 ± 0.709
2.372ValArg: 2.372 ± 0.89
5.534ValSer: 5.534 ± 1.696
3.162ValThr: 3.162 ± 1.507
3.162ValVal: 3.162 ± 1.716
0.0ValTrp: 0.0 ± 0.0
1.581ValTyr: 1.581 ± 0.858
0.0ValXaa: 0.0 ± 0.0
Trp
0.791TrpAla: 0.791 ± 0.53
0.0TrpCys: 0.0 ± 0.0
0.791TrpAsp: 0.791 ± 0.524
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.791TrpIle: 0.791 ± 0.524
0.0TrpLys: 0.0 ± 0.0
2.372TrpLeu: 2.372 ± 0.389
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.791TrpPro: 0.791 ± 0.53
0.791TrpGln: 0.791 ± 0.53
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.791TrpVal: 0.791 ± 0.524
0.0TrpTrp: 0.0 ± 0.0
0.791TrpTyr: 0.791 ± 0.524
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.791TyrAla: 0.791 ± 0.53
2.372TyrCys: 2.372 ± 1.591
3.162TyrAsp: 3.162 ± 1.023
3.953TyrGlu: 3.953 ± 0.184
0.791TyrPhe: 0.791 ± 0.891
0.0TyrGly: 0.0 ± 0.0
0.791TyrHis: 0.791 ± 0.53
1.581TyrIle: 1.581 ± 1.048
5.534TyrLys: 5.534 ± 1.854
3.953TyrLeu: 3.953 ± 0.818
1.581TyrMet: 1.581 ± 0.806
3.162TyrAsn: 3.162 ± 1.387
0.791TyrPro: 0.791 ± 0.524
3.162TyrGln: 3.162 ± 0.36
1.581TyrArg: 1.581 ± 1.048
3.162TyrSer: 3.162 ± 1.387
0.0TyrThr: 0.0 ± 0.0
3.162TyrVal: 3.162 ± 2.096
0.0TyrTrp: 0.0 ± 0.0
2.372TyrTyr: 2.372 ± 1.669
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1266 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski