Amino acid dipepetide frequency for Maize mosaic virus (isolate Maize/United States/Reed/2005) (MMV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.335AlaAla: 5.335 ± 1.145
1.867AlaCys: 1.867 ± 0.662
4.001AlaAsp: 4.001 ± 0.777
3.201AlaGlu: 3.201 ± 0.803
2.934AlaPhe: 2.934 ± 0.874
5.601AlaGly: 5.601 ± 0.739
0.8AlaHis: 0.8 ± 0.452
4.268AlaIle: 4.268 ± 0.931
2.401AlaLys: 2.401 ± 0.764
6.668AlaLeu: 6.668 ± 0.219
1.6AlaMet: 1.6 ± 1.162
1.334AlaAsn: 1.334 ± 0.774
3.468AlaPro: 3.468 ± 1.104
1.6AlaGln: 1.6 ± 0.854
2.667AlaArg: 2.667 ± 0.497
4.801AlaSer: 4.801 ± 1.172
4.001AlaThr: 4.001 ± 1.951
3.468AlaVal: 3.468 ± 1.383
0.533AlaTrp: 0.533 ± 0.302
1.334AlaTyr: 1.334 ± 0.271
0.0AlaXaa: 0.0 ± 0.0
Cys
1.067CysAla: 1.067 ± 0.259
0.267CysCys: 0.267 ± 0.35
1.067CysAsp: 1.067 ± 0.372
1.334CysGlu: 1.334 ± 0.521
0.267CysPhe: 0.267 ± 0.151
0.267CysGly: 0.267 ± 0.371
0.533CysHis: 0.533 ± 0.335
0.8CysIle: 0.8 ± 0.365
0.533CysLys: 0.533 ± 0.335
1.6CysLeu: 1.6 ± 0.728
0.533CysMet: 0.533 ± 0.302
0.0CysAsn: 0.0 ± 0.0
0.8CysPro: 0.8 ± 0.776
1.067CysGln: 1.067 ± 0.372
1.067CysArg: 1.067 ± 0.414
2.134CysSer: 2.134 ± 1.207
1.067CysThr: 1.067 ± 0.259
1.334CysVal: 1.334 ± 0.409
0.267CysTrp: 0.267 ± 0.151
0.267CysTyr: 0.267 ± 0.368
0.0CysXaa: 0.0 ± 0.0
Asp
2.934AspAla: 2.934 ± 0.99
1.334AspCys: 1.334 ± 0.409
3.734AspAsp: 3.734 ± 0.985
3.468AspGlu: 3.468 ± 0.768
1.334AspPhe: 1.334 ± 0.469
2.934AspGly: 2.934 ± 0.623
0.267AspHis: 0.267 ± 0.151
3.734AspIle: 3.734 ± 1.08
2.667AspLys: 2.667 ± 0.768
5.601AspLeu: 5.601 ± 1.052
1.867AspMet: 1.867 ± 0.662
3.201AspAsn: 3.201 ± 0.717
3.734AspPro: 3.734 ± 0.81
1.6AspGln: 1.6 ± 0.34
2.934AspArg: 2.934 ± 1.276
3.468AspSer: 3.468 ± 0.954
4.535AspThr: 4.535 ± 1.304
4.268AspVal: 4.268 ± 1.127
0.8AspTrp: 0.8 ± 0.365
1.6AspTyr: 1.6 ± 0.41
0.0AspXaa: 0.0 ± 0.0
Glu
3.468GluAla: 3.468 ± 1.091
1.334GluCys: 1.334 ± 0.586
4.268GluAsp: 4.268 ± 1.431
4.801GluGlu: 4.801 ± 1.034
1.6GluPhe: 1.6 ± 0.607
4.268GluGly: 4.268 ± 0.759
1.067GluHis: 1.067 ± 0.727
6.402GluIle: 6.402 ± 0.984
2.934GluLys: 2.934 ± 1.195
4.001GluLeu: 4.001 ± 1.124
2.401GluMet: 2.401 ± 0.846
1.6GluAsn: 1.6 ± 0.583
1.867GluPro: 1.867 ± 0.538
0.8GluGln: 0.8 ± 0.393
4.535GluArg: 4.535 ± 1.614
4.001GluSer: 4.001 ± 1.068
3.201GluThr: 3.201 ± 0.603
2.134GluVal: 2.134 ± 1.273
1.067GluTrp: 1.067 ± 0.259
1.067GluTyr: 1.067 ± 0.682
0.0GluXaa: 0.0 ± 0.0
Phe
1.334PheAla: 1.334 ± 0.578
0.0PheCys: 0.0 ± 0.0
1.334PheAsp: 1.334 ± 0.678
1.334PheGlu: 1.334 ± 0.394
1.067PhePhe: 1.067 ± 0.259
2.134PheGly: 2.134 ± 0.426
0.267PheHis: 0.267 ± 0.151
1.6PheIle: 1.6 ± 0.599
1.6PheLys: 1.6 ± 0.41
4.001PheLeu: 4.001 ± 0.552
0.8PheMet: 0.8 ± 0.304
1.067PheAsn: 1.067 ± 0.648
2.401PhePro: 2.401 ± 0.799
0.8PheGln: 0.8 ± 0.365
1.6PheArg: 1.6 ± 0.651
3.734PheSer: 3.734 ± 0.948
2.667PheThr: 2.667 ± 0.441
0.267PheVal: 0.267 ± 0.335
0.8PheTrp: 0.8 ± 0.325
1.6PheTyr: 1.6 ± 0.538
0.0PheXaa: 0.0 ± 0.0
Gly
3.201GlyAla: 3.201 ± 0.919
0.8GlyCys: 0.8 ± 0.58
3.468GlyAsp: 3.468 ± 0.769
4.001GlyGlu: 4.001 ± 1.282
1.6GlyPhe: 1.6 ± 0.757
4.268GlyGly: 4.268 ± 0.651
1.334GlyHis: 1.334 ± 0.586
5.868GlyIle: 5.868 ± 1.089
3.468GlyLys: 3.468 ± 1.339
6.935GlyLeu: 6.935 ± 1.599
2.134GlyMet: 2.134 ± 0.419
2.401GlyAsn: 2.401 ± 0.835
1.334GlyPro: 1.334 ± 0.545
1.334GlyGln: 1.334 ± 0.637
2.401GlyArg: 2.401 ± 0.741
6.668GlySer: 6.668 ± 0.889
5.335GlyThr: 5.335 ± 1.852
4.001GlyVal: 4.001 ± 0.536
1.6GlyTrp: 1.6 ± 0.725
2.134GlyTyr: 2.134 ± 0.405
0.0GlyXaa: 0.0 ± 0.0
His
1.6HisAla: 1.6 ± 0.67
0.533HisCys: 0.533 ± 0.324
1.334HisAsp: 1.334 ± 0.48
1.067HisGlu: 1.067 ± 0.401
0.533HisPhe: 0.533 ± 0.335
2.401HisGly: 2.401 ± 0.508
0.533HisHis: 0.533 ± 0.335
2.401HisIle: 2.401 ± 1.318
0.533HisLys: 0.533 ± 0.302
3.734HisLeu: 3.734 ± 0.912
0.8HisMet: 0.8 ± 0.304
1.067HisAsn: 1.067 ± 0.604
2.134HisPro: 2.134 ± 0.463
0.533HisGln: 0.533 ± 0.302
1.334HisArg: 1.334 ± 0.48
2.401HisSer: 2.401 ± 0.894
0.8HisThr: 0.8 ± 0.393
2.134HisVal: 2.134 ± 1.507
0.0HisTrp: 0.0 ± 0.0
0.533HisTyr: 0.533 ± 0.344
0.267HisXaa: 0.267 ± 0.151
Ile
4.801IleAla: 4.801 ± 0.872
1.334IleCys: 1.334 ± 0.271
3.468IleAsp: 3.468 ± 0.804
4.535IleGlu: 4.535 ± 0.565
1.6IlePhe: 1.6 ± 0.354
2.134IleGly: 2.134 ± 0.586
2.667IleHis: 2.667 ± 0.713
4.001IleIle: 4.001 ± 1.161
5.068IleLys: 5.068 ± 0.708
5.868IleLeu: 5.868 ± 1.251
2.401IleMet: 2.401 ± 0.588
5.068IleAsn: 5.068 ± 0.935
4.001IlePro: 4.001 ± 1.385
2.667IleGln: 2.667 ± 1.249
2.667IleArg: 2.667 ± 0.758
6.402IleSer: 6.402 ± 1.532
4.535IleThr: 4.535 ± 1.549
2.401IleVal: 2.401 ± 0.546
1.867IleTrp: 1.867 ± 0.96
3.201IleTyr: 3.201 ± 0.345
0.267IleXaa: 0.267 ± 0.151
Lys
4.801LysAla: 4.801 ± 0.975
0.533LysCys: 0.533 ± 0.324
2.667LysAsp: 2.667 ± 1.402
4.268LysGlu: 4.268 ± 1.401
0.267LysPhe: 0.267 ± 0.35
3.734LysGly: 3.734 ± 0.711
2.134LysHis: 2.134 ± 0.891
2.934LysIle: 2.934 ± 0.61
3.734LysLys: 3.734 ± 0.428
3.734LysLeu: 3.734 ± 0.602
1.6LysMet: 1.6 ± 0.688
2.134LysAsn: 2.134 ± 0.572
1.6LysPro: 1.6 ± 0.597
0.533LysGln: 0.533 ± 0.324
2.667LysArg: 2.667 ± 0.962
4.268LysSer: 4.268 ± 1.042
2.134LysThr: 2.134 ± 0.977
4.801LysVal: 4.801 ± 1.492
1.334LysTrp: 1.334 ± 0.344
2.667LysTyr: 2.667 ± 0.744
0.0LysXaa: 0.0 ± 0.0
Leu
7.735LeuAla: 7.735 ± 1.856
2.401LeuCys: 2.401 ± 0.926
7.202LeuAsp: 7.202 ± 1.265
6.135LeuGlu: 6.135 ± 1.459
4.001LeuPhe: 4.001 ± 1.109
7.202LeuGly: 7.202 ± 1.706
3.468LeuHis: 3.468 ± 0.758
8.269LeuIle: 8.269 ± 2.072
5.335LeuLys: 5.335 ± 1.002
7.469LeuLeu: 7.469 ± 1.933
2.667LeuMet: 2.667 ± 0.75
4.535LeuAsn: 4.535 ± 0.774
3.734LeuPro: 3.734 ± 1.146
2.134LeuGln: 2.134 ± 1.207
5.068LeuArg: 5.068 ± 1.497
6.668LeuSer: 6.668 ± 0.915
6.935LeuThr: 6.935 ± 1.411
5.601LeuVal: 5.601 ± 0.978
1.067LeuTrp: 1.067 ± 0.39
3.734LeuTyr: 3.734 ± 0.409
0.0LeuXaa: 0.0 ± 0.0
Met
1.067MetAla: 1.067 ± 0.835
0.267MetCys: 0.267 ± 0.151
1.6MetAsp: 1.6 ± 0.674
2.401MetGlu: 2.401 ± 0.582
1.867MetPhe: 1.867 ± 0.581
1.6MetGly: 1.6 ± 0.699
0.8MetHis: 0.8 ± 0.365
1.867MetIle: 1.867 ± 0.684
1.6MetLys: 1.6 ± 0.701
2.134MetLeu: 2.134 ± 0.405
1.067MetMet: 1.067 ± 0.443
1.067MetAsn: 1.067 ± 0.337
0.267MetPro: 0.267 ± 0.151
0.533MetGln: 0.533 ± 0.324
1.6MetArg: 1.6 ± 0.728
3.201MetSer: 3.201 ± 0.85
1.6MetThr: 1.6 ± 0.48
2.667MetVal: 2.667 ± 0.655
0.267MetTrp: 0.267 ± 0.368
0.533MetTyr: 0.533 ± 0.302
0.0MetXaa: 0.0 ± 0.0
Asn
1.067AsnAla: 1.067 ± 0.5
0.8AsnCys: 0.8 ± 0.304
1.334AsnAsp: 1.334 ± 0.48
2.134AsnGlu: 2.134 ± 0.405
1.067AsnPhe: 1.067 ± 0.603
2.134AsnGly: 2.134 ± 0.605
0.8AsnHis: 0.8 ± 0.427
3.468AsnIle: 3.468 ± 0.765
1.334AsnLys: 1.334 ± 0.548
6.935AsnLeu: 6.935 ± 1.153
0.8AsnMet: 0.8 ± 0.657
1.6AsnAsn: 1.6 ± 0.354
2.667AsnPro: 2.667 ± 0.819
1.6AsnGln: 1.6 ± 0.4
2.401AsnArg: 2.401 ± 0.531
2.667AsnSer: 2.667 ± 0.494
2.401AsnThr: 2.401 ± 0.736
2.667AsnVal: 2.667 ± 0.441
0.533AsnTrp: 0.533 ± 0.302
0.267AsnTyr: 0.267 ± 0.151
0.0AsnXaa: 0.0 ± 0.0
Pro
2.667ProAla: 2.667 ± 0.435
0.533ProCys: 0.533 ± 0.302
4.801ProAsp: 4.801 ± 0.685
2.934ProGlu: 2.934 ± 0.812
1.334ProPhe: 1.334 ± 0.586
1.334ProGly: 1.334 ± 0.48
0.533ProHis: 0.533 ± 0.302
3.201ProIle: 3.201 ± 0.51
1.334ProLys: 1.334 ± 0.688
6.135ProLeu: 6.135 ± 1.504
0.533ProMet: 0.533 ± 0.436
1.867ProAsn: 1.867 ± 1.049
0.8ProPro: 0.8 ± 0.893
1.067ProGln: 1.067 ± 0.648
1.6ProArg: 1.6 ± 0.538
4.535ProSer: 4.535 ± 1.314
4.268ProThr: 4.268 ± 1.709
2.934ProVal: 2.934 ± 1.243
0.8ProTrp: 0.8 ± 0.58
1.334ProTyr: 1.334 ± 1.071
0.0ProXaa: 0.0 ± 0.0
Gln
1.334GlnAla: 1.334 ± 0.389
0.533GlnCys: 0.533 ± 0.302
0.8GlnAsp: 0.8 ± 0.393
1.6GlnGlu: 1.6 ± 0.34
1.867GlnPhe: 1.867 ± 0.736
2.934GlnGly: 2.934 ± 0.753
0.8GlnHis: 0.8 ± 0.728
0.8GlnIle: 0.8 ± 0.452
1.6GlnLys: 1.6 ± 0.542
3.734GlnLeu: 3.734 ± 0.802
0.533GlnMet: 0.533 ± 0.344
0.533GlnAsn: 0.533 ± 0.302
0.8GlnPro: 0.8 ± 0.842
0.267GlnGln: 0.267 ± 0.368
1.6GlnArg: 1.6 ± 0.34
1.867GlnSer: 1.867 ± 0.823
1.867GlnThr: 1.867 ± 0.442
2.667GlnVal: 2.667 ± 0.807
0.533GlnTrp: 0.533 ± 0.335
0.8GlnTyr: 0.8 ± 0.372
0.0GlnXaa: 0.0 ± 0.0
Arg
3.201ArgAla: 3.201 ± 0.727
0.8ArgCys: 0.8 ± 0.381
3.201ArgAsp: 3.201 ± 0.943
1.6ArgGlu: 1.6 ± 0.705
1.067ArgPhe: 1.067 ± 0.709
4.268ArgGly: 4.268 ± 0.941
1.067ArgHis: 1.067 ± 0.689
3.734ArgIle: 3.734 ± 1.245
3.201ArgLys: 3.201 ± 0.558
4.801ArgLeu: 4.801 ± 0.874
1.334ArgMet: 1.334 ± 0.469
2.667ArgAsn: 2.667 ± 0.636
0.533ArgPro: 0.533 ± 0.344
3.734ArgGln: 3.734 ± 1.376
3.734ArgArg: 3.734 ± 1.126
5.068ArgSer: 5.068 ± 1.565
4.001ArgThr: 4.001 ± 0.829
3.734ArgVal: 3.734 ± 0.698
0.267ArgTrp: 0.267 ± 0.151
2.134ArgTyr: 2.134 ± 0.426
0.267ArgXaa: 0.267 ± 0.151
Ser
5.068SerAla: 5.068 ± 0.608
0.8SerCys: 0.8 ± 0.304
2.667SerAsp: 2.667 ± 0.494
3.201SerGlu: 3.201 ± 1.107
2.667SerPhe: 2.667 ± 0.825
7.202SerGly: 7.202 ± 1.54
2.934SerHis: 2.934 ± 0.281
4.535SerIle: 4.535 ± 1.222
4.001SerLys: 4.001 ± 1.683
11.47SerLeu: 11.47 ± 1.401
1.867SerMet: 1.867 ± 0.756
1.067SerAsn: 1.067 ± 1.165
5.335SerPro: 5.335 ± 0.958
3.201SerGln: 3.201 ± 0.955
4.801SerArg: 4.801 ± 1.163
9.869SerSer: 9.869 ± 3.109
5.601SerThr: 5.601 ± 1.647
5.068SerVal: 5.068 ± 0.995
2.401SerTrp: 2.401 ± 0.708
4.001SerTyr: 4.001 ± 0.816
0.0SerXaa: 0.0 ± 0.0
Thr
3.201ThrAla: 3.201 ± 1.138
1.067ThrCys: 1.067 ± 0.727
3.468ThrAsp: 3.468 ± 0.889
3.734ThrGlu: 3.734 ± 1.317
2.667ThrPhe: 2.667 ± 1.098
2.934ThrGly: 2.934 ± 1.903
2.401ThrHis: 2.401 ± 0.452
6.135ThrIle: 6.135 ± 1.301
2.401ThrLys: 2.401 ± 0.664
6.668ThrLeu: 6.668 ± 0.47
2.667ThrMet: 2.667 ± 1.297
2.667ThrAsn: 2.667 ± 1.069
2.667ThrPro: 2.667 ± 0.454
1.867ThrGln: 1.867 ± 0.997
4.268ThrArg: 4.268 ± 1.14
5.335ThrSer: 5.335 ± 1.338
6.135ThrThr: 6.135 ± 0.578
5.068ThrVal: 5.068 ± 1.135
2.134ThrTrp: 2.134 ± 0.405
2.667ThrTyr: 2.667 ± 1.459
0.0ThrXaa: 0.0 ± 0.0
Val
4.001ValAla: 4.001 ± 1.189
0.533ValCys: 0.533 ± 0.302
3.201ValAsp: 3.201 ± 0.696
2.667ValGlu: 2.667 ± 0.938
1.334ValPhe: 1.334 ± 0.571
2.934ValGly: 2.934 ± 1.624
1.6ValHis: 1.6 ± 0.629
3.468ValIle: 3.468 ± 0.867
5.601ValLys: 5.601 ± 1.84
6.668ValLeu: 6.668 ± 0.924
1.867ValMet: 1.867 ± 0.618
2.134ValAsn: 2.134 ± 0.755
3.468ValPro: 3.468 ± 0.245
0.8ValGln: 0.8 ± 0.452
2.667ValArg: 2.667 ± 0.706
6.668ValSer: 6.668 ± 1.227
5.335ValThr: 5.335 ± 1.023
1.6ValVal: 1.6 ± 0.618
0.533ValTrp: 0.533 ± 0.302
1.867ValTyr: 1.867 ± 0.559
0.0ValXaa: 0.0 ± 0.0
Trp
1.334TrpAla: 1.334 ± 0.48
0.0TrpCys: 0.0 ± 0.0
0.533TrpAsp: 0.533 ± 0.324
0.8TrpGlu: 0.8 ± 0.452
0.267TrpPhe: 0.267 ± 0.368
1.334TrpGly: 1.334 ± 0.578
0.8TrpHis: 0.8 ± 0.785
1.067TrpIle: 1.067 ± 0.482
1.867TrpLys: 1.867 ± 0.944
0.8TrpLeu: 0.8 ± 0.85
0.0TrpMet: 0.0 ± 0.0
0.533TrpAsn: 0.533 ± 0.302
0.533TrpPro: 0.533 ± 0.302
0.267TrpGln: 0.267 ± 0.35
2.134TrpArg: 2.134 ± 0.645
1.6TrpSer: 1.6 ± 0.47
1.334TrpThr: 1.334 ± 0.271
1.067TrpVal: 1.067 ± 0.68
0.533TrpTrp: 0.533 ± 0.736
1.067TrpTyr: 1.067 ± 1.02
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.667TyrAla: 2.667 ± 1.442
0.533TyrCys: 0.533 ± 0.302
1.867TyrAsp: 1.867 ± 0.663
1.6TyrGlu: 1.6 ± 0.674
1.067TyrPhe: 1.067 ± 1.02
2.667TyrGly: 2.667 ± 1.469
1.867TyrHis: 1.867 ± 0.663
2.401TyrIle: 2.401 ± 0.769
1.067TyrLys: 1.067 ± 0.259
2.667TyrLeu: 2.667 ± 0.761
0.267TyrMet: 0.267 ± 0.363
2.134TyrAsn: 2.134 ± 0.721
2.401TyrPro: 2.401 ± 0.727
1.067TyrGln: 1.067 ± 0.404
2.401TyrArg: 2.401 ± 0.73
2.134TyrSer: 2.134 ± 0.773
2.401TyrThr: 2.401 ± 0.625
1.067TyrVal: 1.067 ± 0.39
0.533TyrTrp: 0.533 ± 0.506
1.334TyrTyr: 1.334 ± 0.271
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.267XaaLys: 0.267 ± 0.151
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.267XaaArg: 0.267 ± 0.151
0.267XaaSer: 0.267 ± 0.151
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (3750 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski