Amino acid dipepetide frequency for Lake Sarah-associated circular virus-40

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.091AlaAla: 3.091 ± 1.809
1.546AlaCys: 1.546 ± 0.905
0.0AlaAsp: 0.0 ± 0.0
1.546AlaGlu: 1.546 ± 0.905
1.546AlaPhe: 1.546 ± 1.489
0.0AlaGly: 0.0 ± 0.0
1.546AlaHis: 1.546 ± 0.905
1.546AlaIle: 1.546 ± 1.489
3.091AlaLys: 3.091 ± 2.979
4.637AlaLeu: 4.637 ± 0.32
1.546AlaMet: 1.546 ± 1.489
4.637AlaAsn: 4.637 ± 4.468
4.637AlaPro: 4.637 ± 0.32
6.182AlaGln: 6.182 ± 1.169
1.546AlaArg: 1.546 ± 1.489
1.546AlaSer: 1.546 ± 0.905
4.637AlaThr: 4.637 ± 0.32
7.728AlaVal: 7.728 ± 2.13
0.0AlaTrp: 0.0 ± 0.0
6.182AlaTyr: 6.182 ± 3.563
0.0AlaXaa: 0.0 ± 0.0
Cys
3.091CysAla: 3.091 ± 2.979
0.0CysCys: 0.0 ± 0.0
1.546CysAsp: 1.546 ± 1.489
0.0CysGlu: 0.0 ± 0.0
1.546CysPhe: 1.546 ± 0.905
1.546CysGly: 1.546 ± 0.905
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.546CysLys: 1.546 ± 0.905
1.546CysLeu: 1.546 ± 1.489
1.546CysMet: 1.546 ± 0.905
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.546CysSer: 1.546 ± 0.905
1.546CysThr: 1.546 ± 0.905
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
0.0AspAla: 0.0 ± 0.0
0.0AspCys: 0.0 ± 0.0
1.546AspAsp: 1.546 ± 0.905
1.546AspGlu: 1.546 ± 0.905
6.182AspPhe: 6.182 ± 1.225
0.0AspGly: 0.0 ± 0.0
0.0AspHis: 0.0 ± 0.0
3.091AspIle: 3.091 ± 1.809
1.546AspLys: 1.546 ± 0.905
1.546AspLeu: 1.546 ± 0.905
3.091AspMet: 3.091 ± 1.809
0.0AspAsn: 0.0 ± 0.0
0.0AspPro: 0.0 ± 0.0
1.546AspGln: 1.546 ± 0.905
6.182AspArg: 6.182 ± 1.169
4.637AspSer: 4.637 ± 0.32
1.546AspThr: 1.546 ± 0.905
4.637AspVal: 4.637 ± 0.32
1.546AspTrp: 1.546 ± 1.489
3.091AspTyr: 3.091 ± 0.585
0.0AspXaa: 0.0 ± 0.0
Glu
1.546GluAla: 1.546 ± 0.905
0.0GluCys: 0.0 ± 0.0
1.546GluAsp: 1.546 ± 0.905
6.182GluGlu: 6.182 ± 3.619
3.091GluPhe: 3.091 ± 1.809
4.637GluGly: 4.637 ± 2.714
0.0GluHis: 0.0 ± 0.0
1.546GluIle: 1.546 ± 0.905
9.274GluLys: 9.274 ± 3.034
9.274GluLeu: 9.274 ± 0.64
4.637GluMet: 4.637 ± 2.306
1.546GluAsn: 1.546 ± 0.905
3.091GluPro: 3.091 ± 0.585
3.091GluGln: 3.091 ± 0.585
0.0GluArg: 0.0 ± 0.0
3.091GluSer: 3.091 ± 0.585
3.091GluThr: 3.091 ± 1.809
0.0GluVal: 0.0 ± 0.0
0.0GluTrp: 0.0 ± 0.0
4.637GluTyr: 4.637 ± 2.714
0.0GluXaa: 0.0 ± 0.0
Phe
3.091PheAla: 3.091 ± 2.979
3.091PheCys: 3.091 ± 0.585
1.546PheAsp: 1.546 ± 0.905
1.546PheGlu: 1.546 ± 0.905
1.546PhePhe: 1.546 ± 1.489
0.0PheGly: 0.0 ± 0.0
1.546PheHis: 1.546 ± 0.905
1.546PheIle: 1.546 ± 0.905
0.0PheLys: 0.0 ± 0.0
1.546PheLeu: 1.546 ± 0.905
0.0PheMet: 0.0 ± 0.888
1.546PheAsn: 1.546 ± 0.905
0.0PhePro: 0.0 ± 0.0
1.546PheGln: 1.546 ± 1.489
4.637PheArg: 4.637 ± 2.074
1.546PheSer: 1.546 ± 1.489
3.091PheThr: 3.091 ± 1.809
3.091PheVal: 3.091 ± 2.979
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
6.182GlyAla: 6.182 ± 1.169
1.546GlyCys: 1.546 ± 1.489
4.637GlyAsp: 4.637 ± 2.714
1.546GlyGlu: 1.546 ± 0.905
0.0GlyPhe: 0.0 ± 0.0
13.91GlyGly: 13.91 ± 0.96
0.0GlyHis: 0.0 ± 0.0
1.546GlyIle: 1.546 ± 1.489
7.728GlyLys: 7.728 ± 2.13
1.546GlyLeu: 1.546 ± 1.489
0.0GlyMet: 0.0 ± 0.0
0.0GlyAsn: 0.0 ± 0.0
4.637GlyPro: 4.637 ± 0.32
3.091GlyGln: 3.091 ± 1.809
3.091GlyArg: 3.091 ± 0.585
4.637GlySer: 4.637 ± 0.32
12.365GlyThr: 12.365 ± 0.056
4.637GlyVal: 4.637 ± 2.074
0.0GlyTrp: 0.0 ± 0.0
1.546GlyTyr: 1.546 ± 0.905
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
1.546HisAsp: 1.546 ± 0.905
3.091HisGlu: 3.091 ± 1.809
1.546HisPhe: 1.546 ± 0.905
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
1.546HisLeu: 1.546 ± 0.905
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
3.091HisPro: 3.091 ± 1.809
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
1.546HisVal: 1.546 ± 0.905
1.546HisTrp: 1.546 ± 0.905
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.091IleAla: 3.091 ± 2.979
0.0IleCys: 0.0 ± 0.0
1.546IleAsp: 1.546 ± 0.905
3.091IleGlu: 3.091 ± 1.809
0.0IlePhe: 0.0 ± 0.0
4.637IleGly: 4.637 ± 0.32
0.0IleHis: 0.0 ± 0.0
1.546IleIle: 1.546 ± 0.905
0.0IleLys: 0.0 ± 0.0
3.091IleLeu: 3.091 ± 0.585
0.0IleMet: 0.0 ± 0.0
0.0IleAsn: 0.0 ± 0.0
1.546IlePro: 1.546 ± 0.905
0.0IleGln: 0.0 ± 0.0
3.091IleArg: 3.091 ± 0.585
6.182IleSer: 6.182 ± 3.619
6.182IleThr: 6.182 ± 1.225
1.546IleVal: 1.546 ± 1.489
7.728IleTrp: 7.728 ± 0.265
1.546IleTyr: 1.546 ± 0.905
0.0IleXaa: 0.0 ± 0.0
Lys
4.637LysAla: 4.637 ± 0.32
0.0LysCys: 0.0 ± 0.0
0.0LysAsp: 0.0 ± 0.0
6.182LysGlu: 6.182 ± 3.619
0.0LysPhe: 0.0 ± 0.0
4.637LysGly: 4.637 ± 2.714
0.0LysHis: 0.0 ± 0.0
1.546LysIle: 1.546 ± 0.905
7.728LysLys: 7.728 ± 0.265
6.182LysLeu: 6.182 ± 1.169
3.091LysMet: 3.091 ± 0.585
1.546LysAsn: 1.546 ± 1.489
1.546LysPro: 1.546 ± 0.905
3.091LysGln: 3.091 ± 1.809
9.274LysArg: 9.274 ± 0.64
3.091LysSer: 3.091 ± 1.809
4.637LysThr: 4.637 ± 0.32
3.091LysVal: 3.091 ± 0.585
0.0LysTrp: 0.0 ± 0.0
7.728LysTyr: 7.728 ± 2.659
0.0LysXaa: 0.0 ± 0.0
Leu
4.637LeuAla: 4.637 ± 0.32
0.0LeuCys: 0.0 ± 0.0
7.728LeuAsp: 7.728 ± 2.13
1.546LeuGlu: 1.546 ± 1.489
4.637LeuPhe: 4.637 ± 2.074
4.637LeuGly: 4.637 ± 4.468
0.0LeuHis: 0.0 ± 0.0
4.637LeuIle: 4.637 ± 0.32
4.637LeuLys: 4.637 ± 0.32
3.091LeuLeu: 3.091 ± 0.585
0.0LeuMet: 0.0 ± 0.0
6.182LeuAsn: 6.182 ± 1.169
1.546LeuPro: 1.546 ± 0.905
7.728LeuGln: 7.728 ± 2.659
4.637LeuArg: 4.637 ± 0.32
4.637LeuSer: 4.637 ± 2.074
3.091LeuThr: 3.091 ± 0.585
6.182LeuVal: 6.182 ± 1.225
1.546LeuTrp: 1.546 ± 0.905
0.0LeuTyr: 0.0 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
6.182MetAla: 6.182 ± 1.225
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
3.091MetGlu: 3.091 ± 1.809
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.546MetLys: 1.546 ± 0.905
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
3.091MetPro: 3.091 ± 2.979
0.0MetGln: 0.0 ± 0.0
3.091MetArg: 3.091 ± 0.585
0.0MetSer: 0.0 ± 0.0
0.0MetThr: 0.0 ± 0.0
3.091MetVal: 3.091 ± 0.585
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
1.546AsnGlu: 1.546 ± 0.905
3.091AsnPhe: 3.091 ± 0.585
3.091AsnGly: 3.091 ± 2.979
0.0AsnHis: 0.0 ± 0.0
0.0AsnIle: 0.0 ± 0.0
4.637AsnLys: 4.637 ± 0.32
6.182AsnLeu: 6.182 ± 1.169
1.546AsnMet: 1.546 ± 1.489
4.637AsnAsn: 4.637 ± 2.074
0.0AsnPro: 0.0 ± 0.0
4.637AsnGln: 4.637 ± 4.468
3.091AsnArg: 3.091 ± 0.585
4.637AsnSer: 4.637 ± 0.32
4.637AsnThr: 4.637 ± 4.468
4.637AsnVal: 4.637 ± 2.074
0.0AsnTrp: 0.0 ± 0.0
3.091AsnTyr: 3.091 ± 1.809
0.0AsnXaa: 0.0 ± 0.0
Pro
1.546ProAla: 1.546 ± 0.905
0.0ProCys: 0.0 ± 0.0
3.091ProAsp: 3.091 ± 1.809
4.637ProGlu: 4.637 ± 0.32
0.0ProPhe: 0.0 ± 0.0
7.728ProGly: 7.728 ± 0.265
1.546ProHis: 1.546 ± 0.905
0.0ProIle: 0.0 ± 0.0
1.546ProLys: 1.546 ± 1.489
3.091ProLeu: 3.091 ± 1.809
0.0ProMet: 0.0 ± 0.0
3.091ProAsn: 3.091 ± 0.585
3.091ProPro: 3.091 ± 1.809
1.546ProGln: 1.546 ± 0.905
1.546ProArg: 1.546 ± 0.905
4.637ProSer: 4.637 ± 2.074
4.637ProThr: 4.637 ± 0.32
3.091ProVal: 3.091 ± 0.585
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
4.637GlnAla: 4.637 ± 4.468
1.546GlnCys: 1.546 ± 0.905
0.0GlnAsp: 0.0 ± 0.0
4.637GlnGlu: 4.637 ± 2.714
0.0GlnPhe: 0.0 ± 0.0
4.637GlnGly: 4.637 ± 0.32
0.0GlnHis: 0.0 ± 0.0
3.091GlnIle: 3.091 ± 2.979
3.091GlnLys: 3.091 ± 1.809
3.091GlnLeu: 3.091 ± 0.585
1.546GlnMet: 1.546 ± 0.905
7.728GlnAsn: 7.728 ± 0.265
6.182GlnPro: 6.182 ± 1.169
0.0GlnGln: 0.0 ± 0.0
1.546GlnArg: 1.546 ± 0.905
4.637GlnSer: 4.637 ± 0.32
1.546GlnThr: 1.546 ± 1.489
0.0GlnVal: 0.0 ± 0.0
3.091GlnTrp: 3.091 ± 0.585
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
7.728ArgAla: 7.728 ± 0.265
0.0ArgCys: 0.0 ± 0.0
3.091ArgAsp: 3.091 ± 0.585
1.546ArgGlu: 1.546 ± 0.905
3.091ArgPhe: 3.091 ± 2.979
4.637ArgGly: 4.637 ± 0.32
1.546ArgHis: 1.546 ± 0.905
6.182ArgIle: 6.182 ± 1.225
4.637ArgLys: 4.637 ± 4.468
1.546ArgLeu: 1.546 ± 1.489
1.546ArgMet: 1.546 ± 1.489
1.546ArgAsn: 1.546 ± 1.489
1.546ArgPro: 1.546 ± 0.905
1.546ArgGln: 1.546 ± 1.489
4.637ArgArg: 4.637 ± 0.32
3.091ArgSer: 3.091 ± 1.809
9.274ArgThr: 9.274 ± 1.754
3.091ArgVal: 3.091 ± 1.809
3.091ArgTrp: 3.091 ± 0.585
4.637ArgTyr: 4.637 ± 2.714
0.0ArgXaa: 0.0 ± 0.0
Ser
0.0SerAla: 0.0 ± 0.0
3.091SerCys: 3.091 ± 0.585
4.637SerAsp: 4.637 ± 2.074
3.091SerGlu: 3.091 ± 0.585
1.546SerPhe: 1.546 ± 0.905
10.819SerGly: 10.819 ± 0.849
0.0SerHis: 0.0 ± 0.0
1.546SerIle: 1.546 ± 1.489
3.091SerLys: 3.091 ± 0.585
6.182SerLeu: 6.182 ± 3.563
0.0SerMet: 0.0 ± 0.0
6.182SerAsn: 6.182 ± 1.169
1.546SerPro: 1.546 ± 0.905
4.637SerGln: 4.637 ± 0.32
4.637SerArg: 4.637 ± 2.714
7.728SerSer: 7.728 ± 4.524
6.182SerThr: 6.182 ± 1.225
6.182SerVal: 6.182 ± 1.225
3.091SerTrp: 3.091 ± 0.585
1.546SerTyr: 1.546 ± 0.905
0.0SerXaa: 0.0 ± 0.0
Thr
0.0ThrAla: 0.0 ± 0.0
1.546ThrCys: 1.546 ± 1.489
4.637ThrAsp: 4.637 ± 0.32
6.182ThrGlu: 6.182 ± 1.225
1.546ThrPhe: 1.546 ± 1.489
6.182ThrGly: 6.182 ± 1.225
1.546ThrHis: 1.546 ± 0.905
3.091ThrIle: 3.091 ± 0.585
4.637ThrLys: 4.637 ± 2.714
9.274ThrLeu: 9.274 ± 1.754
0.0ThrMet: 0.0 ± 0.0
4.637ThrAsn: 4.637 ± 0.32
6.182ThrPro: 6.182 ± 1.225
1.546ThrGln: 1.546 ± 0.905
7.728ThrArg: 7.728 ± 0.265
9.274ThrSer: 9.274 ± 4.148
10.819ThrThr: 10.819 ± 3.243
3.091ThrVal: 3.091 ± 0.585
1.546ThrTrp: 1.546 ± 0.905
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
4.637ValAla: 4.637 ± 0.32
0.0ValCys: 0.0 ± 0.0
1.546ValAsp: 1.546 ± 1.489
6.182ValGlu: 6.182 ± 1.169
3.091ValPhe: 3.091 ± 2.979
0.0ValGly: 0.0 ± 0.0
3.091ValHis: 3.091 ± 1.809
7.728ValIle: 7.728 ± 2.13
6.182ValLys: 6.182 ± 3.619
4.637ValLeu: 4.637 ± 0.32
0.0ValMet: 0.0 ± 0.0
1.546ValAsn: 1.546 ± 1.489
1.546ValPro: 1.546 ± 1.489
6.182ValGln: 6.182 ± 1.169
6.182ValArg: 6.182 ± 1.169
1.546ValSer: 1.546 ± 0.905
3.091ValThr: 3.091 ± 0.585
1.546ValVal: 1.546 ± 0.905
1.546ValTrp: 1.546 ± 1.489
4.637ValTyr: 4.637 ± 0.32
0.0ValXaa: 0.0 ± 0.0
Trp
3.091TrpAla: 3.091 ± 0.585
1.546TrpCys: 1.546 ± 0.905
0.0TrpAsp: 0.0 ± 0.0
1.546TrpGlu: 1.546 ± 0.905
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
1.546TrpHis: 1.546 ± 0.905
6.182TrpIle: 6.182 ± 3.619
1.546TrpLys: 1.546 ± 0.905
1.546TrpLeu: 1.546 ± 1.489
0.0TrpMet: 0.0 ± 0.0
3.091TrpAsn: 3.091 ± 2.979
0.0TrpPro: 0.0 ± 0.0
1.546TrpGln: 1.546 ± 0.905
0.0TrpArg: 0.0 ± 0.0
3.091TrpSer: 3.091 ± 2.979
0.0TrpThr: 0.0 ± 0.0
1.546TrpVal: 1.546 ± 1.489
1.546TrpTrp: 1.546 ± 0.905
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
1.546TyrCys: 1.546 ± 0.905
3.091TyrAsp: 3.091 ± 1.809
1.546TyrGlu: 1.546 ± 0.905
0.0TyrPhe: 0.0 ± 0.0
1.546TyrGly: 1.546 ± 0.905
1.546TyrHis: 1.546 ± 0.905
0.0TyrIle: 0.0 ± 0.0
1.546TyrLys: 1.546 ± 1.489
1.546TyrLeu: 1.546 ± 0.905
0.0TyrMet: 0.0 ± 0.0
1.546TyrAsn: 1.546 ± 1.489
1.546TyrPro: 1.546 ± 0.905
3.091TyrGln: 3.091 ± 1.809
3.091TyrArg: 3.091 ± 2.979
6.182TyrSer: 6.182 ± 1.169
3.091TyrThr: 3.091 ± 0.585
6.182TyrVal: 6.182 ± 1.225
1.546TyrTrp: 1.546 ± 0.905
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (648 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski