Amino acid dipepetide frequency for Adelphocoris suturalis virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.995AlaAla: 3.995 ± 3.095
0.285AlaCys: 0.285 ± 0.142
4.566AlaAsp: 4.566 ± 1.189
4.566AlaGlu: 4.566 ± 2.13
2.283AlaPhe: 2.283 ± 1.044
0.856AlaGly: 0.856 ± 0.332
2.568AlaHis: 2.568 ± 0.435
5.708AlaIle: 5.708 ± 1.092
2.854AlaLys: 2.854 ± 0.98
4.566AlaLeu: 4.566 ± 1.953
1.142AlaMet: 1.142 ± 0.492
1.427AlaAsn: 1.427 ± 0.37
3.995AlaPro: 3.995 ± 1.045
1.142AlaGln: 1.142 ± 0.45
2.568AlaArg: 2.568 ± 1.358
5.137AlaSer: 5.137 ± 1.643
5.422AlaThr: 5.422 ± 0.91
5.708AlaVal: 5.708 ± 1.188
0.285AlaTrp: 0.285 ± 0.582
2.568AlaTyr: 2.568 ± 1.358
0.0AlaXaa: 0.0 ± 0.0
Cys
1.142CysAla: 1.142 ± 0.321
0.0CysCys: 0.0 ± 0.0
0.285CysAsp: 0.285 ± 0.142
0.856CysGlu: 0.856 ± 0.332
0.571CysPhe: 0.571 ± 0.284
0.571CysGly: 0.571 ± 0.396
0.285CysHis: 0.285 ± 0.142
0.856CysIle: 0.856 ± 0.332
1.142CysLys: 1.142 ± 0.545
1.142CysLeu: 1.142 ± 0.59
0.285CysMet: 0.285 ± 0.432
1.712CysAsn: 1.712 ± 0.459
1.427CysPro: 1.427 ± 0.71
0.571CysGln: 0.571 ± 0.396
0.285CysArg: 0.285 ± 0.494
3.71CysSer: 3.71 ± 1.293
1.142CysThr: 1.142 ± 0.321
0.571CysVal: 0.571 ± 0.284
0.0CysTrp: 0.0 ± 0.0
1.142CysTyr: 1.142 ± 0.568
0.0CysXaa: 0.0 ± 0.0
Asp
2.283AspAla: 2.283 ± 0.374
1.427AspCys: 1.427 ± 0.716
3.71AspAsp: 3.71 ± 0.723
3.71AspGlu: 3.71 ± 0.483
5.137AspPhe: 5.137 ± 0.91
3.71AspGly: 3.71 ± 1.061
1.427AspHis: 1.427 ± 1.587
2.283AspIle: 2.283 ± 0.693
2.568AspLys: 2.568 ± 0.66
8.562AspLeu: 8.562 ± 0.689
0.856AspMet: 0.856 ± 0.457
1.998AspAsn: 1.998 ± 0.484
3.139AspPro: 3.139 ± 1.089
1.427AspGln: 1.427 ± 0.71
5.137AspArg: 5.137 ± 0.425
5.422AspSer: 5.422 ± 1.431
3.139AspThr: 3.139 ± 0.822
4.852AspVal: 4.852 ± 1.248
0.571AspTrp: 0.571 ± 0.284
2.568AspTyr: 2.568 ± 0.821
0.0AspXaa: 0.0 ± 0.0
Glu
4.281GluAla: 4.281 ± 2.879
0.571GluCys: 0.571 ± 0.396
3.425GluAsp: 3.425 ± 1.129
1.142GluGlu: 1.142 ± 0.722
3.995GluPhe: 3.995 ± 0.671
2.283GluGly: 2.283 ± 0.715
2.568GluHis: 2.568 ± 0.647
4.852GluIle: 4.852 ± 0.661
3.425GluLys: 3.425 ± 0.759
4.566GluLeu: 4.566 ± 2.427
0.856GluMet: 0.856 ± 0.426
1.998GluAsn: 1.998 ± 0.693
2.568GluPro: 2.568 ± 0.788
0.571GluGln: 0.571 ± 0.284
3.71GluArg: 3.71 ± 0.397
2.283GluSer: 2.283 ± 0.693
2.283GluThr: 2.283 ± 0.613
4.566GluVal: 4.566 ± 0.568
0.285GluTrp: 0.285 ± 0.142
2.854GluTyr: 2.854 ± 0.899
0.0GluXaa: 0.0 ± 0.0
Phe
3.71PheAla: 3.71 ± 0.738
1.712PheCys: 1.712 ± 0.459
2.568PheAsp: 2.568 ± 0.337
3.139PheGlu: 3.139 ± 1.388
2.568PhePhe: 2.568 ± 0.989
3.139PheGly: 3.139 ± 1.264
0.285PheHis: 0.285 ± 0.494
1.712PheIle: 1.712 ± 1.232
4.281PheLys: 4.281 ± 1.64
4.852PheLeu: 4.852 ± 0.523
0.285PheMet: 0.285 ± 0.142
2.568PheAsn: 2.568 ± 1.277
2.283PhePro: 2.283 ± 0.374
1.142PheGln: 1.142 ± 0.568
4.852PheArg: 4.852 ± 0.856
5.422PheSer: 5.422 ± 1.281
1.998PheThr: 1.998 ± 0.607
2.854PheVal: 2.854 ± 0.49
0.0PheTrp: 0.0 ± 0.0
1.142PheTyr: 1.142 ± 0.321
0.0PheXaa: 0.0 ± 0.0
Gly
2.568GlyAla: 2.568 ± 0.59
1.142GlyCys: 1.142 ± 0.792
3.71GlyAsp: 3.71 ± 1.845
1.712GlyGlu: 1.712 ± 0.851
2.283GlyPhe: 2.283 ± 1.135
1.712GlyGly: 1.712 ± 0.851
0.856GlyHis: 0.856 ± 0.426
2.568GlyIle: 2.568 ± 0.337
2.283GlyLys: 2.283 ± 1.044
2.854GlyLeu: 2.854 ± 1.82
1.142GlyMet: 1.142 ± 0.321
3.139GlyAsn: 3.139 ± 1.138
1.712GlyPro: 1.712 ± 0.404
0.571GlyGln: 0.571 ± 0.284
1.712GlyArg: 1.712 ± 0.699
4.281GlySer: 4.281 ± 1.261
2.854GlyThr: 2.854 ± 1.647
3.139GlyVal: 3.139 ± 1.04
0.0GlyTrp: 0.0 ± 0.0
0.285GlyTyr: 0.285 ± 0.142
0.0GlyXaa: 0.0 ± 0.0
His
3.139HisAla: 3.139 ± 1.089
0.0HisCys: 0.0 ± 0.0
1.998HisAsp: 1.998 ± 0.828
1.427HisGlu: 1.427 ± 0.526
0.571HisPhe: 0.571 ± 0.988
0.571HisGly: 0.571 ± 0.284
1.142HisHis: 1.142 ± 0.45
1.142HisIle: 1.142 ± 1.112
1.712HisLys: 1.712 ± 0.663
4.852HisLeu: 4.852 ± 1.361
0.285HisMet: 0.285 ± 0.142
1.712HisAsn: 1.712 ± 0.559
1.142HisPro: 1.142 ± 0.539
0.856HisGln: 0.856 ± 0.719
1.998HisArg: 1.998 ± 1.399
3.71HisSer: 3.71 ± 1.541
1.142HisThr: 1.142 ± 0.321
1.998HisVal: 1.998 ± 0.57
0.856HisTrp: 0.856 ± 0.87
2.283HisTyr: 2.283 ± 1.135
0.0HisXaa: 0.0 ± 0.0
Ile
2.283IleAla: 2.283 ± 1.274
0.856IleCys: 0.856 ± 0.332
3.71IleAsp: 3.71 ± 1.21
3.139IleGlu: 3.139 ± 1.082
3.139IlePhe: 3.139 ± 1.26
1.427IleGly: 1.427 ± 0.37
1.998IleHis: 1.998 ± 0.637
4.281IleIle: 4.281 ± 1.384
2.283IleLys: 2.283 ± 0.693
6.279IleLeu: 6.279 ± 1.726
0.856IleMet: 0.856 ± 0.456
3.425IleAsn: 3.425 ± 0.469
3.995IlePro: 3.995 ± 0.537
1.142IleGln: 1.142 ± 0.568
2.283IleArg: 2.283 ± 0.374
3.71IleSer: 3.71 ± 0.493
4.566IleThr: 4.566 ± 0.67
6.279IleVal: 6.279 ± 1.667
0.285IleTrp: 0.285 ± 0.142
3.995IleTyr: 3.995 ± 1.798
0.0IleXaa: 0.0 ± 0.0
Lys
1.427LysAla: 1.427 ± 0.487
0.856LysCys: 0.856 ± 0.332
1.998LysAsp: 1.998 ± 0.57
2.283LysGlu: 2.283 ± 0.693
2.854LysPhe: 2.854 ± 0.391
3.139LysGly: 3.139 ± 0.512
2.568LysHis: 2.568 ± 0.995
3.71LysIle: 3.71 ± 1.052
2.568LysLys: 2.568 ± 1.504
4.852LysLeu: 4.852 ± 1.491
0.856LysMet: 0.856 ± 0.426
2.283LysAsn: 2.283 ± 1.221
2.854LysPro: 2.854 ± 0.954
1.998LysGln: 1.998 ± 0.607
3.139LysArg: 3.139 ± 0.744
5.708LysSer: 5.708 ± 1.481
2.283LysThr: 2.283 ± 0.875
3.425LysVal: 3.425 ± 0.857
0.571LysTrp: 0.571 ± 0.284
4.281LysTyr: 4.281 ± 0.901
0.0LysXaa: 0.0 ± 0.0
Leu
5.137LeuAla: 5.137 ± 2.242
1.712LeuCys: 1.712 ± 0.851
7.42LeuAsp: 7.42 ± 0.981
4.566LeuGlu: 4.566 ± 1.124
3.71LeuPhe: 3.71 ± 1.009
4.566LeuGly: 4.566 ± 1.04
2.568LeuHis: 2.568 ± 1.159
4.281LeuIle: 4.281 ± 1.188
5.137LeuLys: 5.137 ± 0.98
11.13LeuLeu: 11.13 ± 2.419
2.854LeuMet: 2.854 ± 0.975
3.425LeuAsn: 3.425 ± 1.212
6.279LeuPro: 6.279 ± 0.528
3.139LeuGln: 3.139 ± 0.742
6.564LeuArg: 6.564 ± 1.177
9.132LeuSer: 9.132 ± 1.568
6.564LeuThr: 6.564 ± 1.262
5.708LeuVal: 5.708 ± 0.916
0.856LeuTrp: 0.856 ± 0.426
2.854LeuTyr: 2.854 ± 1.64
0.0LeuXaa: 0.0 ± 0.0
Met
1.998MetAla: 1.998 ± 0.868
0.0MetCys: 0.0 ± 0.0
0.856MetAsp: 0.856 ± 0.529
0.571MetGlu: 0.571 ± 0.284
0.856MetPhe: 0.856 ± 0.332
0.856MetGly: 0.856 ± 0.332
0.571MetHis: 0.571 ± 0.284
1.142MetIle: 1.142 ± 0.321
0.856MetLys: 0.856 ± 0.332
3.139MetLeu: 3.139 ± 0.638
0.571MetMet: 0.571 ± 0.396
1.142MetAsn: 1.142 ± 0.722
0.856MetPro: 0.856 ± 0.456
1.427MetGln: 1.427 ± 0.895
0.285MetArg: 0.285 ± 0.494
0.856MetSer: 0.856 ± 0.332
1.142MetThr: 1.142 ± 0.568
0.285MetVal: 0.285 ± 0.142
0.285MetTrp: 0.285 ± 0.142
0.856MetTyr: 0.856 ± 0.332
0.0MetXaa: 0.0 ± 0.0
Asn
4.281AsnAla: 4.281 ± 0.514
1.142AsnCys: 1.142 ± 0.568
1.427AsnAsp: 1.427 ± 1.443
2.283AsnGlu: 2.283 ± 0.662
2.283AsnPhe: 2.283 ± 2.355
1.712AsnGly: 1.712 ± 0.663
0.856AsnHis: 0.856 ± 0.426
1.998AsnIle: 1.998 ± 1.22
2.854AsnLys: 2.854 ± 1.04
3.71AsnLeu: 3.71 ± 0.909
0.856AsnMet: 0.856 ± 0.456
1.998AsnAsn: 1.998 ± 1.283
2.283AsnPro: 2.283 ± 0.693
1.998AsnGln: 1.998 ± 0.993
2.854AsnArg: 2.854 ± 1.009
2.568AsnSer: 2.568 ± 0.884
0.571AsnThr: 0.571 ± 0.284
3.71AsnVal: 3.71 ± 0.806
0.856AsnTrp: 0.856 ± 0.456
2.283AsnTyr: 2.283 ± 0.339
0.0AsnXaa: 0.0 ± 0.0
Pro
4.566ProAla: 4.566 ± 1.286
1.142ProCys: 1.142 ± 0.792
3.995ProAsp: 3.995 ± 1.31
3.71ProGlu: 3.71 ± 0.995
1.427ProPhe: 1.427 ± 1.94
2.568ProGly: 2.568 ± 0.821
2.283ProHis: 2.283 ± 0.875
3.425ProIle: 3.425 ± 0.919
2.568ProLys: 2.568 ± 0.821
3.995ProLeu: 3.995 ± 1.141
0.856ProMet: 0.856 ± 0.456
1.142ProAsn: 1.142 ± 0.568
2.854ProPro: 2.854 ± 0.964
1.427ProGln: 1.427 ± 0.71
2.854ProArg: 2.854 ± 0.391
4.281ProSer: 4.281 ± 1.152
3.71ProThr: 3.71 ± 0.397
3.425ProVal: 3.425 ± 0.594
0.0ProTrp: 0.0 ± 0.0
1.712ProTyr: 1.712 ± 0.559
0.0ProXaa: 0.0 ± 0.0
Gln
1.142GlnAla: 1.142 ± 1.006
0.856GlnCys: 0.856 ± 0.426
1.998GlnAsp: 1.998 ± 0.57
0.571GlnGlu: 0.571 ± 0.284
1.712GlnPhe: 1.712 ± 0.459
1.427GlnGly: 1.427 ± 0.71
1.427GlnHis: 1.427 ± 1.088
2.283GlnIle: 2.283 ± 0.854
1.142GlnLys: 1.142 ± 0.963
3.71GlnLeu: 3.71 ± 1.845
0.285GlnMet: 0.285 ± 0.559
0.571GlnAsn: 0.571 ± 0.664
1.142GlnPro: 1.142 ± 0.722
1.142GlnGln: 1.142 ± 0.568
1.998GlnArg: 1.998 ± 1.696
1.142GlnSer: 1.142 ± 0.568
1.427GlnThr: 1.427 ± 0.485
1.712GlnVal: 1.712 ± 0.459
0.0GlnTrp: 0.0 ± 0.0
0.285GlnTyr: 0.285 ± 0.142
0.0GlnXaa: 0.0 ± 0.0
Arg
2.568ArgAla: 2.568 ± 0.583
1.427ArgCys: 1.427 ± 0.37
3.995ArgAsp: 3.995 ± 0.804
4.281ArgGlu: 4.281 ± 2.086
3.139ArgPhe: 3.139 ± 0.827
3.139ArgGly: 3.139 ± 1.018
1.142ArgHis: 1.142 ± 0.568
2.854ArgIle: 2.854 ± 1.035
2.854ArgLys: 2.854 ± 1.419
3.425ArgLeu: 3.425 ± 0.469
0.571ArgMet: 0.571 ± 0.664
2.283ArgAsn: 2.283 ± 0.374
3.139ArgPro: 3.139 ± 1.089
1.998ArgGln: 1.998 ± 1.283
1.998ArgArg: 1.998 ± 0.76
8.276ArgSer: 8.276 ± 2.904
2.568ArgThr: 2.568 ± 1.159
3.995ArgVal: 3.995 ± 0.537
0.285ArgTrp: 0.285 ± 0.142
3.425ArgTyr: 3.425 ± 0.897
0.0ArgXaa: 0.0 ± 0.0
Ser
7.705SerAla: 7.705 ± 2.137
1.427SerCys: 1.427 ± 0.716
4.852SerAsp: 4.852 ± 0.843
3.425SerGlu: 3.425 ± 0.663
4.852SerPhe: 4.852 ± 1.532
2.568SerGly: 2.568 ± 0.821
2.854SerHis: 2.854 ± 0.964
5.137SerIle: 5.137 ± 0.909
4.852SerLys: 4.852 ± 1.513
9.418SerLeu: 9.418 ± 2.506
2.854SerMet: 2.854 ± 1.626
4.281SerAsn: 4.281 ± 0.744
3.995SerPro: 3.995 ± 1.501
1.998SerGln: 1.998 ± 0.395
5.137SerArg: 5.137 ± 1.412
9.418SerSer: 9.418 ± 0.825
4.566SerThr: 4.566 ± 0.443
6.849SerVal: 6.849 ± 2.936
0.0SerTrp: 0.0 ± 0.0
3.995SerTyr: 3.995 ± 0.724
0.0SerXaa: 0.0 ± 0.0
Thr
2.568ThrAla: 2.568 ± 0.435
0.285ThrCys: 0.285 ± 0.142
4.281ThrAsp: 4.281 ± 1.207
2.854ThrGlu: 2.854 ± 0.74
2.854ThrPhe: 2.854 ± 0.49
2.283ThrGly: 2.283 ± 0.689
2.854ThrHis: 2.854 ± 2.096
3.995ThrIle: 3.995 ± 1.141
3.425ThrLys: 3.425 ± 0.663
5.708ThrLeu: 5.708 ± 1.507
0.856ThrMet: 0.856 ± 0.426
2.854ThrAsn: 2.854 ± 1.704
2.568ThrPro: 2.568 ± 1.125
1.998ThrGln: 1.998 ± 0.868
2.568ThrArg: 2.568 ± 0.435
3.139ThrSer: 3.139 ± 1.488
3.139ThrThr: 3.139 ± 0.416
4.566ThrVal: 4.566 ± 1.04
0.856ThrTrp: 0.856 ± 0.332
2.283ThrTyr: 2.283 ± 0.875
0.0ThrXaa: 0.0 ± 0.0
Val
4.566ValAla: 4.566 ± 1.812
1.427ValCys: 1.427 ± 0.544
4.852ValAsp: 4.852 ± 0.966
5.422ValGlu: 5.422 ± 1.204
2.854ValPhe: 2.854 ± 0.954
2.854ValGly: 2.854 ± 0.758
1.998ValHis: 1.998 ± 1.109
3.995ValIle: 3.995 ± 2.826
4.281ValLys: 4.281 ± 0.775
6.279ValLeu: 6.279 ± 0.681
1.427ValMet: 1.427 ± 0.71
2.568ValAsn: 2.568 ± 1.536
3.995ValPro: 3.995 ± 0.67
0.856ValGln: 0.856 ± 0.332
4.281ValArg: 4.281 ± 1.417
6.849ValSer: 6.849 ± 1.312
3.425ValThr: 3.425 ± 1.366
6.564ValVal: 6.564 ± 2.054
0.571ValTrp: 0.571 ± 0.284
4.281ValTyr: 4.281 ± 0.775
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.571TrpCys: 0.571 ± 0.503
0.571TrpAsp: 0.571 ± 0.284
0.571TrpGlu: 0.571 ± 0.284
0.285TrpPhe: 0.285 ± 0.142
0.285TrpGly: 0.285 ± 0.142
0.571TrpHis: 0.571 ± 0.503
0.285TrpIle: 0.285 ± 0.142
0.571TrpLys: 0.571 ± 0.396
0.856TrpLeu: 0.856 ± 0.426
0.0TrpMet: 0.0 ± 0.0
0.285TrpAsn: 0.285 ± 0.607
0.285TrpPro: 0.285 ± 0.142
0.285TrpGln: 0.285 ± 0.582
0.571TrpArg: 0.571 ± 0.284
0.285TrpSer: 0.285 ± 0.142
0.0TrpThr: 0.0 ± 0.0
0.285TrpVal: 0.285 ± 0.142
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.568TyrAla: 2.568 ± 0.75
0.856TyrCys: 0.856 ± 0.426
3.71TyrAsp: 3.71 ± 0.82
2.854TyrGlu: 2.854 ± 0.948
3.139TyrPhe: 3.139 ± 1.241
0.856TyrGly: 0.856 ± 0.426
1.712TyrHis: 1.712 ± 0.851
3.425TyrIle: 3.425 ± 1.119
1.998TyrLys: 1.998 ± 0.484
3.71TyrLeu: 3.71 ± 1.061
0.571TyrMet: 0.571 ± 0.284
1.712TyrAsn: 1.712 ± 0.559
1.427TyrPro: 1.427 ± 0.37
0.285TyrGln: 0.285 ± 0.582
2.568TyrArg: 2.568 ± 0.788
4.852TyrSer: 4.852 ± 1.958
3.995TyrThr: 3.995 ± 0.387
2.854TyrVal: 2.854 ± 0.667
0.0TyrTrp: 0.0 ± 0.0
3.425TyrTyr: 3.425 ± 2.326
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (3505 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski