Amino acid dipepetide frequency for Turnip curly top virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.398AlaAla: 4.398 ± 1.633
1.759AlaCys: 1.759 ± 0.974
0.0AlaAsp: 0.0 ± 0.0
3.518AlaGlu: 3.518 ± 1.058
2.639AlaPhe: 2.639 ± 1.868
2.639AlaGly: 2.639 ± 0.788
0.88AlaHis: 0.88 ± 0.816
1.759AlaIle: 1.759 ± 1.247
2.639AlaLys: 2.639 ± 1.025
5.277AlaLeu: 5.277 ± 2.049
0.88AlaMet: 0.88 ± 0.719
1.759AlaAsn: 1.759 ± 0.685
4.398AlaPro: 4.398 ± 1.875
1.759AlaGln: 1.759 ± 0.685
4.398AlaArg: 4.398 ± 1.437
3.518AlaSer: 3.518 ± 1.17
2.639AlaThr: 2.639 ± 1.478
1.759AlaVal: 1.759 ± 0.685
0.88AlaTrp: 0.88 ± 0.719
1.759AlaTyr: 1.759 ± 1.974
0.0AlaXaa: 0.0 ± 0.0
Cys
0.88CysAla: 0.88 ± 0.624
0.0CysCys: 0.0 ± 0.0
0.88CysAsp: 0.88 ± 0.816
0.88CysGlu: 0.88 ± 0.987
0.0CysPhe: 0.0 ± 0.0
0.88CysGly: 0.88 ± 0.959
1.759CysHis: 1.759 ± 1.247
0.88CysIle: 0.88 ± 0.816
2.639CysLys: 2.639 ± 2.088
0.88CysLeu: 0.88 ± 1.151
0.0CysMet: 0.0 ± 0.0
0.88CysAsn: 0.88 ± 0.624
0.88CysPro: 0.88 ± 0.624
0.0CysGln: 0.0 ± 0.0
0.88CysArg: 0.88 ± 0.624
0.88CysSer: 0.88 ± 0.987
0.88CysThr: 0.88 ± 0.816
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.639AspAla: 2.639 ± 1.025
0.88AspCys: 0.88 ± 0.816
6.157AspAsp: 6.157 ± 2.093
2.639AspGlu: 2.639 ± 2.961
2.639AspPhe: 2.639 ± 1.094
2.639AspGly: 2.639 ± 1.871
0.0AspHis: 0.0 ± 0.0
1.759AspIle: 1.759 ± 0.685
2.639AspLys: 2.639 ± 0.976
5.277AspLeu: 5.277 ± 1.964
0.88AspMet: 0.88 ± 0.816
3.518AspAsn: 3.518 ± 2.151
4.398AspPro: 4.398 ± 1.8
1.759AspGln: 1.759 ± 0.685
1.759AspArg: 1.759 ± 1.023
1.759AspSer: 1.759 ± 0.685
0.88AspThr: 0.88 ± 0.816
2.639AspVal: 2.639 ± 1.871
3.518AspTrp: 3.518 ± 2.046
2.639AspTyr: 2.639 ± 1.025
0.0AspXaa: 0.0 ± 0.0
Glu
7.036GluAla: 7.036 ± 2.01
0.88GluCys: 0.88 ± 0.959
1.759GluAsp: 1.759 ± 0.685
7.916GluGlu: 7.916 ± 2.837
5.277GluPhe: 5.277 ± 1.227
2.639GluGly: 2.639 ± 1.396
0.88GluHis: 0.88 ± 0.816
2.639GluIle: 2.639 ± 1.828
4.398GluLys: 4.398 ± 1.136
1.759GluLeu: 1.759 ± 1.502
0.88GluMet: 0.88 ± 1.151
0.88GluAsn: 0.88 ± 0.624
2.639GluPro: 2.639 ± 1.341
0.0GluGln: 0.0 ± 0.0
1.759GluArg: 1.759 ± 1.023
5.277GluSer: 5.277 ± 1.362
1.759GluThr: 1.759 ± 1.974
4.398GluVal: 4.398 ± 2.095
2.639GluTrp: 2.639 ± 0.976
2.639GluTyr: 2.639 ± 1.3
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.0PheCys: 0.0 ± 0.0
4.398PheAsp: 4.398 ± 0.845
1.759PheGlu: 1.759 ± 1.023
2.639PhePhe: 2.639 ± 1.094
0.88PheGly: 0.88 ± 0.816
1.759PheHis: 1.759 ± 0.877
2.639PheIle: 2.639 ± 1.372
0.88PheLys: 0.88 ± 0.987
5.277PheLeu: 5.277 ± 2.101
0.0PheMet: 0.0 ± 0.0
7.036PheAsn: 7.036 ± 2.654
2.639PhePro: 2.639 ± 1.868
2.639PheGln: 2.639 ± 1.304
3.518PheArg: 3.518 ± 2.334
2.639PheSer: 2.639 ± 1.372
4.398PheThr: 4.398 ± 2.102
1.759PheVal: 1.759 ± 0.877
0.88PheTrp: 0.88 ± 0.816
2.639PheTyr: 2.639 ± 1.562
0.0PheXaa: 0.0 ± 0.0
Gly
3.518GlyAla: 3.518 ± 1.552
0.0GlyCys: 0.0 ± 0.0
3.518GlyAsp: 3.518 ± 1.37
6.157GlyGlu: 6.157 ± 1.353
1.759GlyPhe: 1.759 ± 1.099
5.277GlyGly: 5.277 ± 2.055
0.88GlyHis: 0.88 ± 0.624
5.277GlyIle: 5.277 ± 1.818
3.518GlyLys: 3.518 ± 1.552
1.759GlyLeu: 1.759 ± 1.099
0.0GlyMet: 0.0 ± 0.0
1.759GlyAsn: 1.759 ± 1.152
2.639GlyPro: 2.639 ± 1.025
2.639GlyGln: 2.639 ± 0.871
2.639GlyArg: 2.639 ± 0.871
2.639GlySer: 2.639 ± 1.396
4.398GlyThr: 4.398 ± 1.222
3.518GlyVal: 3.518 ± 1.698
0.88GlyTrp: 0.88 ± 0.816
1.759GlyTyr: 1.759 ± 0.685
0.0GlyXaa: 0.0 ± 0.0
His
1.759HisAla: 1.759 ± 1.023
0.88HisCys: 0.88 ± 0.624
1.759HisAsp: 1.759 ± 1.22
1.759HisGlu: 1.759 ± 1.599
1.759HisPhe: 1.759 ± 0.685
1.759HisGly: 1.759 ± 1.919
1.759HisHis: 1.759 ± 1.919
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
5.277HisLeu: 5.277 ± 2.282
1.759HisMet: 1.759 ± 1.045
1.759HisAsn: 1.759 ± 1.247
0.88HisPro: 0.88 ± 0.624
3.518HisGln: 3.518 ± 2.21
2.639HisArg: 2.639 ± 1.59
0.0HisSer: 0.0 ± 0.0
1.759HisThr: 1.759 ± 1.023
2.639HisVal: 2.639 ± 1.373
0.88HisTrp: 0.88 ± 0.624
1.759HisTyr: 1.759 ± 0.685
0.0HisXaa: 0.0 ± 0.0
Ile
0.88IleAla: 0.88 ± 0.959
2.639IleCys: 2.639 ± 1.025
4.398IleAsp: 4.398 ± 2.468
4.398IleGlu: 4.398 ± 1.742
6.157IlePhe: 6.157 ± 1.319
4.398IleGly: 4.398 ± 1.222
5.277IleHis: 5.277 ± 2.88
5.277IleIle: 5.277 ± 2.103
2.639IleLys: 2.639 ± 0.788
3.518IleLeu: 3.518 ± 1.058
0.88IleMet: 0.88 ± 0.959
1.759IleAsn: 1.759 ± 1.045
2.639IlePro: 2.639 ± 1.396
4.398IleGln: 4.398 ± 2.468
3.518IleArg: 3.518 ± 1.096
6.157IleSer: 6.157 ± 4.23
6.157IleThr: 6.157 ± 3.107
0.88IleVal: 0.88 ± 0.816
1.759IleTrp: 1.759 ± 1.251
2.639IleTyr: 2.639 ± 1.433
0.0IleXaa: 0.0 ± 0.0
Lys
3.518LysAla: 3.518 ± 2.597
0.88LysCys: 0.88 ± 0.959
6.157LysAsp: 6.157 ± 2.776
6.157LysGlu: 6.157 ± 1.683
2.639LysPhe: 2.639 ± 0.788
2.639LysGly: 2.639 ± 1.372
1.759LysHis: 1.759 ± 1.247
3.518LysIle: 3.518 ± 1.617
4.398LysLys: 4.398 ± 1.337
1.759LysLeu: 1.759 ± 0.877
1.759LysMet: 1.759 ± 0.93
0.88LysAsn: 0.88 ± 0.624
6.157LysPro: 6.157 ± 1.684
1.759LysGln: 1.759 ± 1.045
5.277LysArg: 5.277 ± 3.013
6.157LysSer: 6.157 ± 1.996
4.398LysThr: 4.398 ± 1.941
2.639LysVal: 2.639 ± 1.025
0.0LysTrp: 0.0 ± 0.0
4.398LysTyr: 4.398 ± 1.437
0.0LysXaa: 0.0 ± 0.0
Leu
4.398LeuAla: 4.398 ± 2.8
1.759LeuCys: 1.759 ± 0.974
4.398LeuAsp: 4.398 ± 1.426
1.759LeuGlu: 1.759 ± 1.247
3.518LeuPhe: 3.518 ± 1.443
2.639LeuGly: 2.639 ± 1.478
2.639LeuHis: 2.639 ± 1.373
3.518LeuIle: 3.518 ± 1.641
10.554LeuLys: 10.554 ± 2.552
5.277LeuLeu: 5.277 ± 1.525
3.518LeuMet: 3.518 ± 1.375
4.398LeuAsn: 4.398 ± 1.597
2.639LeuPro: 2.639 ± 1.883
6.157LeuGln: 6.157 ± 2.972
5.277LeuArg: 5.277 ± 2.004
3.518LeuSer: 3.518 ± 2.503
4.398LeuThr: 4.398 ± 1.557
2.639LeuVal: 2.639 ± 1.952
0.88LeuTrp: 0.88 ± 0.624
1.759LeuTyr: 1.759 ± 0.685
0.0LeuXaa: 0.0 ± 0.0
Met
1.759MetAla: 1.759 ± 1.045
0.88MetCys: 0.88 ± 1.151
0.88MetAsp: 0.88 ± 0.959
1.759MetGlu: 1.759 ± 1.152
0.0MetPhe: 0.0 ± 0.0
0.88MetGly: 0.88 ± 1.151
2.639MetHis: 2.639 ± 2.153
0.88MetIle: 0.88 ± 0.987
3.518MetLys: 3.518 ± 0.824
0.88MetLeu: 0.88 ± 0.816
0.88MetMet: 0.88 ± 1.151
0.88MetAsn: 0.88 ± 0.719
0.88MetPro: 0.88 ± 0.624
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
0.88MetSer: 0.88 ± 0.816
1.759MetThr: 1.759 ± 1.632
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
3.518MetTyr: 3.518 ± 3.264
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
0.0AsnCys: 0.0 ± 0.0
3.518AsnAsp: 3.518 ± 1.37
0.88AsnGlu: 0.88 ± 0.624
3.518AsnPhe: 3.518 ± 1.641
3.518AsnGly: 3.518 ± 1.442
0.88AsnHis: 0.88 ± 0.624
6.157AsnIle: 6.157 ± 1.748
2.639AsnLys: 2.639 ± 1.868
7.916AsnLeu: 7.916 ± 2.201
0.0AsnMet: 0.0 ± 0.0
2.639AsnAsn: 2.639 ± 1.732
3.518AsnPro: 3.518 ± 1.899
1.759AsnGln: 1.759 ± 1.152
1.759AsnArg: 1.759 ± 1.152
3.518AsnSer: 3.518 ± 1.552
0.0AsnThr: 0.0 ± 0.0
3.518AsnVal: 3.518 ± 0.97
0.0AsnTrp: 0.0 ± 0.0
5.277AsnTyr: 5.277 ± 2.423
0.0AsnXaa: 0.0 ± 0.0
Pro
3.518ProAla: 3.518 ± 1.513
0.88ProCys: 0.88 ± 0.959
0.88ProAsp: 0.88 ± 0.987
1.759ProGlu: 1.759 ± 1.023
1.759ProPhe: 1.759 ± 1.091
5.277ProGly: 5.277 ± 1.768
2.639ProHis: 2.639 ± 1.871
4.398ProIle: 4.398 ± 1.733
6.157ProLys: 6.157 ± 1.096
3.518ProLeu: 3.518 ± 1.951
0.0ProMet: 0.0 ± 0.0
4.398ProAsn: 4.398 ± 1.392
3.518ProPro: 3.518 ± 2.046
0.88ProGln: 0.88 ± 0.959
3.518ProArg: 3.518 ± 2.495
8.795ProSer: 8.795 ± 2.697
0.88ProThr: 0.88 ± 1.151
4.398ProVal: 4.398 ± 2.853
0.0ProTrp: 0.0 ± 0.0
0.88ProTyr: 0.88 ± 0.816
0.0ProXaa: 0.0 ± 0.0
Gln
2.639GlnAla: 2.639 ± 0.951
0.88GlnCys: 0.88 ± 0.624
0.0GlnAsp: 0.0 ± 0.0
2.639GlnGlu: 2.639 ± 1.478
3.518GlnPhe: 3.518 ± 1.552
0.88GlnGly: 0.88 ± 0.624
0.88GlnHis: 0.88 ± 0.959
4.398GlnIle: 4.398 ± 1.29
0.88GlnLys: 0.88 ± 0.624
4.398GlnLeu: 4.398 ± 1.735
0.0GlnMet: 0.0 ± 0.0
2.639GlnAsn: 2.639 ± 1.025
1.759GlnPro: 1.759 ± 1.04
1.759GlnGln: 1.759 ± 0.974
3.518GlnArg: 3.518 ± 1.505
4.398GlnSer: 4.398 ± 2.537
2.639GlnThr: 2.639 ± 1.396
0.88GlnVal: 0.88 ± 0.719
0.88GlnTrp: 0.88 ± 0.816
1.759GlnTyr: 1.759 ± 0.685
0.0GlnXaa: 0.0 ± 0.0
Arg
1.759ArgAla: 1.759 ± 1.251
0.0ArgCys: 0.0 ± 0.0
4.398ArgAsp: 4.398 ± 2.175
2.639ArgGlu: 2.639 ± 1.559
4.398ArgPhe: 4.398 ± 2.256
3.518ArgGly: 3.518 ± 1.236
2.639ArgHis: 2.639 ± 1.341
5.277ArgIle: 5.277 ± 2.293
1.759ArgLys: 1.759 ± 1.045
4.398ArgLeu: 4.398 ± 1.871
1.759ArgMet: 1.759 ± 1.076
2.639ArgAsn: 2.639 ± 1.13
1.759ArgPro: 1.759 ± 0.685
1.759ArgGln: 1.759 ± 0.877
7.036ArgArg: 7.036 ± 3.893
6.157ArgSer: 6.157 ± 1.452
4.398ArgThr: 4.398 ± 1.579
5.277ArgVal: 5.277 ± 2.419
1.759ArgTrp: 1.759 ± 1.632
0.88ArgTyr: 0.88 ± 0.987
0.0ArgXaa: 0.0 ± 0.0
Ser
1.759SerAla: 1.759 ± 1.22
0.88SerCys: 0.88 ± 0.987
3.518SerAsp: 3.518 ± 1.37
1.759SerGlu: 1.759 ± 1.251
1.759SerPhe: 1.759 ± 1.251
4.398SerGly: 4.398 ± 1.392
1.759SerHis: 1.759 ± 0.877
6.157SerIle: 6.157 ± 3.287
3.518SerLys: 3.518 ± 1.17
5.277SerLeu: 5.277 ± 1.333
2.639SerMet: 2.639 ± 2.153
1.759SerAsn: 1.759 ± 1.247
6.157SerPro: 6.157 ± 2.432
0.88SerGln: 0.88 ± 0.959
7.916SerArg: 7.916 ± 2.608
12.313SerSer: 12.313 ± 7.427
7.036SerThr: 7.036 ± 1.919
4.398SerVal: 4.398 ± 2.175
2.639SerTrp: 2.639 ± 0.871
2.639SerTyr: 2.639 ± 1.871
0.0SerXaa: 0.0 ± 0.0
Thr
3.518ThrAla: 3.518 ± 1.37
0.0ThrCys: 0.0 ± 0.0
1.759ThrAsp: 1.759 ± 0.974
2.639ThrGlu: 2.639 ± 1.433
1.759ThrPhe: 1.759 ± 1.632
5.277ThrGly: 5.277 ± 1.623
5.277ThrHis: 5.277 ± 2.983
3.518ThrIle: 3.518 ± 1.543
4.398ThrLys: 4.398 ± 1.426
1.759ThrLeu: 1.759 ± 1.023
2.639ThrMet: 2.639 ± 2.558
1.759ThrAsn: 1.759 ± 1.023
6.157ThrPro: 6.157 ± 0.962
3.518ThrGln: 3.518 ± 1.17
0.88ThrArg: 0.88 ± 0.987
2.639ThrSer: 2.639 ± 2.288
1.759ThrThr: 1.759 ± 0.877
2.639ThrVal: 2.639 ± 1.13
0.88ThrTrp: 0.88 ± 0.816
1.759ThrTyr: 1.759 ± 0.877
0.0ThrXaa: 0.0 ± 0.0
Val
4.398ValAla: 4.398 ± 2.364
0.88ValCys: 0.88 ± 0.816
0.88ValAsp: 0.88 ± 0.624
3.518ValGlu: 3.518 ± 1.798
1.759ValPhe: 1.759 ± 0.974
1.759ValGly: 1.759 ± 0.685
0.0ValHis: 0.0 ± 0.0
6.157ValIle: 6.157 ± 2.327
2.639ValLys: 2.639 ± 1.372
6.157ValLeu: 6.157 ± 1.756
0.88ValMet: 0.88 ± 0.816
2.639ValAsn: 2.639 ± 2.487
3.518ValPro: 3.518 ± 1.45
2.639ValGln: 2.639 ± 2.267
4.398ValArg: 4.398 ± 2.585
1.759ValSer: 1.759 ± 0.685
0.88ValThr: 0.88 ± 0.816
0.88ValVal: 0.88 ± 0.719
0.0ValTrp: 0.0 ± 0.0
1.759ValTyr: 1.759 ± 1.023
0.0ValXaa: 0.0 ± 0.0
Trp
0.88TrpAla: 0.88 ± 0.624
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.88TrpGlu: 0.88 ± 0.816
0.0TrpPhe: 0.0 ± 0.0
0.88TrpGly: 0.88 ± 0.624
0.0TrpHis: 0.0 ± 0.0
1.759TrpIle: 1.759 ± 1.045
1.759TrpLys: 1.759 ± 0.685
0.88TrpLeu: 0.88 ± 0.624
0.0TrpMet: 0.0 ± 0.0
2.639TrpAsn: 2.639 ± 1.353
0.0TrpPro: 0.0 ± 0.0
1.759TrpGln: 1.759 ± 0.685
0.88TrpArg: 0.88 ± 0.987
2.639TrpSer: 2.639 ± 1.372
3.518TrpThr: 3.518 ± 1.636
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
0.0TyrCys: 0.0 ± 0.0
1.759TyrAsp: 1.759 ± 1.04
2.639TyrGlu: 2.639 ± 1.631
0.88TyrPhe: 0.88 ± 0.816
1.759TyrGly: 1.759 ± 0.877
0.0TyrHis: 0.0 ± 0.0
4.398TyrIle: 4.398 ± 2.488
5.277TyrLys: 5.277 ± 1.988
4.398TyrLeu: 4.398 ± 1.753
2.639TyrMet: 2.639 ± 1.679
4.398TyrAsn: 4.398 ± 2.488
0.88TyrPro: 0.88 ± 0.624
1.759TyrGln: 1.759 ± 0.685
2.639TyrArg: 2.639 ± 0.871
3.518TyrSer: 3.518 ± 2.502
0.88TyrThr: 0.88 ± 0.987
2.639TyrVal: 2.639 ± 1.372
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1138 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski