Amino acid dipepetide frequency for Seal anellovirus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.323AlaAla: 1.323 ± 0.755
1.323AlaCys: 1.323 ± 0.755
2.646AlaAsp: 2.646 ± 1.51
1.323AlaGlu: 1.323 ± 0.755
1.323AlaPhe: 1.323 ± 0.755
7.937AlaGly: 7.937 ± 1.07
0.0AlaHis: 0.0 ± 0.0
2.646AlaIle: 2.646 ± 3.363
1.323AlaLys: 1.323 ± 0.755
0.0AlaLeu: 0.0 ± 0.0
1.323AlaMet: 1.323 ± 0.648
0.0AlaAsn: 0.0 ± 0.0
3.968AlaPro: 3.968 ± 0.793
3.968AlaGln: 3.968 ± 0.793
2.646AlaArg: 2.646 ± 1.51
2.646AlaSer: 2.646 ± 3.363
3.968AlaThr: 3.968 ± 2.265
6.614AlaVal: 6.614 ± 3.558
1.323AlaTrp: 1.323 ± 0.755
1.323AlaTyr: 1.323 ± 0.755
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.323CysCys: 1.323 ± 0.755
0.0CysAsp: 0.0 ± 0.0
1.323CysGlu: 1.323 ± 0.755
1.323CysPhe: 1.323 ± 0.755
1.323CysGly: 1.323 ± 0.755
0.0CysHis: 0.0 ± 0.0
2.646CysIle: 2.646 ± 1.817
1.323CysLys: 1.323 ± 0.755
1.323CysLeu: 1.323 ± 2.104
0.0CysMet: 0.0 ± 0.0
2.646CysAsn: 2.646 ± 1.51
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
1.323CysThr: 1.323 ± 0.755
1.323CysVal: 1.323 ± 0.755
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
0.0AspAla: 0.0 ± 0.0
1.323AspCys: 1.323 ± 0.755
2.646AspAsp: 2.646 ± 1.817
3.968AspGlu: 3.968 ± 0.793
1.323AspPhe: 1.323 ± 1.681
3.968AspGly: 3.968 ± 2.265
1.323AspHis: 1.323 ± 2.104
1.323AspIle: 1.323 ± 0.755
2.646AspLys: 2.646 ± 1.51
9.259AspLeu: 9.259 ± 3.361
0.0AspMet: 0.0 ± 0.0
2.646AspAsn: 2.646 ± 1.817
7.937AspPro: 7.937 ± 2.425
1.323AspGln: 1.323 ± 0.755
0.0AspArg: 0.0 ± 0.0
7.937AspSer: 7.937 ± 1.585
2.646AspThr: 2.646 ± 1.076
3.968AspVal: 3.968 ± 2.72
2.646AspTrp: 2.646 ± 3.363
3.968AspTyr: 3.968 ± 1.821
0.0AspXaa: 0.0 ± 0.0
Glu
5.291GluAla: 5.291 ± 3.02
0.0GluCys: 0.0 ± 0.0
6.614GluAsp: 6.614 ± 3.78
0.0GluGlu: 0.0 ± 0.0
0.0GluPhe: 0.0 ± 0.0
3.968GluGly: 3.968 ± 1.821
0.0GluHis: 0.0 ± 0.0
0.0GluIle: 0.0 ± 0.0
1.323GluLys: 1.323 ± 0.755
1.323GluLeu: 1.323 ± 1.681
0.0GluMet: 0.0 ± 0.0
0.0GluAsn: 0.0 ± 0.0
2.646GluPro: 2.646 ± 1.076
0.0GluGln: 0.0 ± 0.0
2.646GluArg: 2.646 ± 1.817
3.968GluSer: 3.968 ± 2.72
2.646GluThr: 2.646 ± 3.363
1.323GluVal: 1.323 ± 0.755
1.323GluTrp: 1.323 ± 1.681
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.646PheAla: 2.646 ± 1.076
2.646PheCys: 2.646 ± 1.51
3.968PheAsp: 3.968 ± 2.098
0.0PheGlu: 0.0 ± 0.0
1.323PhePhe: 1.323 ± 0.755
5.291PheGly: 5.291 ± 1.113
2.646PheHis: 2.646 ± 1.51
1.323PheIle: 1.323 ± 0.755
2.646PheLys: 2.646 ± 1.51
5.291PheLeu: 5.291 ± 3.34
3.968PheMet: 3.968 ± 1.057
0.0PheAsn: 0.0 ± 0.0
1.323PhePro: 1.323 ± 2.104
1.323PheGln: 1.323 ± 0.755
2.646PheArg: 2.646 ± 1.51
1.323PheSer: 1.323 ± 0.755
0.0PheThr: 0.0 ± 0.0
0.0PheVal: 0.0 ± 0.0
2.646PheTrp: 2.646 ± 1.51
1.323PheTyr: 1.323 ± 1.681
0.0PheXaa: 0.0 ± 0.0
Gly
5.291GlyAla: 5.291 ± 2.114
0.0GlyCys: 0.0 ± 0.0
6.614GlyAsp: 6.614 ± 1.729
2.646GlyGlu: 2.646 ± 1.817
2.646GlyPhe: 2.646 ± 2.786
3.968GlyGly: 3.968 ± 0.793
2.646GlyHis: 2.646 ± 1.51
2.646GlyIle: 2.646 ± 1.51
2.646GlyLys: 2.646 ± 1.076
5.291GlyLeu: 5.291 ± 1.113
1.323GlyMet: 1.323 ± 2.104
1.323GlyAsn: 1.323 ± 0.755
6.614GlyPro: 6.614 ± 1.733
1.323GlyGln: 1.323 ± 1.681
3.968GlyArg: 3.968 ± 2.265
3.968GlySer: 3.968 ± 2.098
7.937GlyThr: 7.937 ± 2.425
5.291GlyVal: 5.291 ± 3.02
3.968GlyTrp: 3.968 ± 1.821
3.968GlyTyr: 3.968 ± 0.793
0.0GlyXaa: 0.0 ± 0.0
His
1.323HisAla: 1.323 ± 1.681
0.0HisCys: 0.0 ± 0.0
2.646HisAsp: 2.646 ± 1.817
0.0HisGlu: 0.0 ± 0.0
1.323HisPhe: 1.323 ± 1.681
1.323HisGly: 1.323 ± 0.755
3.968HisHis: 3.968 ± 2.265
0.0HisIle: 0.0 ± 0.0
1.323HisLys: 1.323 ± 0.755
1.323HisLeu: 1.323 ± 0.755
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
5.291HisPro: 5.291 ± 3.02
3.968HisGln: 3.968 ± 2.72
3.968HisArg: 3.968 ± 2.265
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
1.323HisTrp: 1.323 ± 0.755
1.323HisTyr: 1.323 ± 0.755
0.0HisXaa: 0.0 ± 0.0
Ile
2.646IleAla: 2.646 ± 2.786
1.323IleCys: 1.323 ± 2.104
1.323IleAsp: 1.323 ± 0.755
1.323IleGlu: 1.323 ± 2.104
1.323IlePhe: 1.323 ± 0.755
0.0IleGly: 0.0 ± 0.0
0.0IleHis: 0.0 ± 0.0
2.646IleIle: 2.646 ± 1.51
0.0IleLys: 0.0 ± 0.0
5.291IleLeu: 5.291 ± 3.02
0.0IleMet: 0.0 ± 0.0
2.646IleAsn: 2.646 ± 2.786
5.291IlePro: 5.291 ± 2.114
3.968IleGln: 3.968 ± 2.72
3.968IleArg: 3.968 ± 2.098
2.646IleSer: 2.646 ± 1.51
2.646IleThr: 2.646 ± 1.51
1.323IleVal: 1.323 ± 2.104
1.323IleTrp: 1.323 ± 0.755
3.968IleTyr: 3.968 ± 3.858
0.0IleXaa: 0.0 ± 0.0
Lys
1.323LysAla: 1.323 ± 1.681
0.0LysCys: 0.0 ± 0.0
3.968LysAsp: 3.968 ± 0.793
0.0LysGlu: 0.0 ± 0.0
3.968LysPhe: 3.968 ± 2.265
6.614LysGly: 6.614 ± 1.733
1.323LysHis: 1.323 ± 0.755
2.646LysIle: 2.646 ± 1.817
2.646LysLys: 2.646 ± 1.51
2.646LysLeu: 2.646 ± 1.51
0.0LysMet: 0.0 ± 1.614
1.323LysAsn: 1.323 ± 0.755
2.646LysPro: 2.646 ± 1.076
2.646LysGln: 2.646 ± 1.51
5.291LysArg: 5.291 ± 1.475
1.323LysSer: 1.323 ± 0.755
2.646LysThr: 2.646 ± 1.51
2.646LysVal: 2.646 ± 1.51
1.323LysTrp: 1.323 ± 0.755
3.968LysTyr: 3.968 ± 0.793
0.0LysXaa: 0.0 ± 0.0
Leu
3.968LeuAla: 3.968 ± 2.098
0.0LeuCys: 0.0 ± 0.0
7.937LeuAsp: 7.937 ± 1.585
2.646LeuGlu: 2.646 ± 1.076
2.646LeuPhe: 2.646 ± 3.363
6.614LeuGly: 6.614 ± 1.729
0.0LeuHis: 0.0 ± 0.0
6.614LeuIle: 6.614 ± 8.7
2.646LeuLys: 2.646 ± 1.51
3.968LeuLeu: 3.968 ± 0.793
1.323LeuMet: 1.323 ± 0.755
2.646LeuAsn: 2.646 ± 2.786
3.968LeuPro: 3.968 ± 1.821
3.968LeuGln: 3.968 ± 4.094
5.291LeuArg: 5.291 ± 1.113
5.291LeuSer: 5.291 ± 2.152
5.291LeuThr: 5.291 ± 3.02
6.614LeuVal: 6.614 ± 4.854
0.0LeuTrp: 0.0 ± 0.0
3.968LeuTyr: 3.968 ± 2.265
0.0LeuXaa: 0.0 ± 0.0
Met
1.323MetAla: 1.323 ± 0.755
0.0MetCys: 0.0 ± 0.0
1.323MetAsp: 1.323 ± 2.104
0.0MetGlu: 0.0 ± 0.0
1.323MetPhe: 1.323 ± 0.755
1.323MetGly: 1.323 ± 2.104
0.0MetHis: 0.0 ± 0.0
1.323MetIle: 1.323 ± 1.681
1.323MetLys: 1.323 ± 0.755
0.0MetLeu: 0.0 ± 0.0
1.323MetMet: 1.323 ± 1.681
2.646MetAsn: 2.646 ± 1.51
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
1.323MetArg: 1.323 ± 1.681
0.0MetSer: 0.0 ± 0.0
1.323MetThr: 1.323 ± 1.681
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.323AsnAla: 1.323 ± 0.755
1.323AsnCys: 1.323 ± 0.755
0.0AsnAsp: 0.0 ± 0.0
1.323AsnGlu: 1.323 ± 1.681
1.323AsnPhe: 1.323 ± 0.755
0.0AsnGly: 0.0 ± 0.0
1.323AsnHis: 1.323 ± 1.681
0.0AsnIle: 0.0 ± 0.0
0.0AsnLys: 0.0 ± 0.0
2.646AsnLeu: 2.646 ± 1.076
1.323AsnMet: 1.323 ± 1.681
3.968AsnAsn: 3.968 ± 1.821
1.323AsnPro: 1.323 ± 1.681
2.646AsnGln: 2.646 ± 1.817
2.646AsnArg: 2.646 ± 1.51
0.0AsnSer: 0.0 ± 0.0
5.291AsnThr: 5.291 ± 2.114
0.0AsnVal: 0.0 ± 0.0
1.323AsnTrp: 1.323 ± 0.755
1.323AsnTyr: 1.323 ± 2.104
0.0AsnXaa: 0.0 ± 0.0
Pro
5.291ProAla: 5.291 ± 1.113
1.323ProCys: 1.323 ± 0.755
3.968ProAsp: 3.968 ± 0.793
1.323ProGlu: 1.323 ± 1.681
5.291ProPhe: 5.291 ± 1.113
10.582ProGly: 10.582 ± 2.621
3.968ProHis: 3.968 ± 2.72
1.323ProIle: 1.323 ± 1.681
2.646ProLys: 2.646 ± 1.076
5.291ProLeu: 5.291 ± 4.061
0.0ProMet: 0.0 ± 0.0
1.323ProAsn: 1.323 ± 1.681
13.228ProPro: 13.228 ± 1.201
2.646ProGln: 2.646 ± 1.51
3.968ProArg: 3.968 ± 2.265
6.614ProSer: 6.614 ± 2.601
2.646ProThr: 2.646 ± 1.076
0.0ProVal: 0.0 ± 0.0
2.646ProTrp: 2.646 ± 1.51
5.291ProTyr: 5.291 ± 1.113
0.0ProXaa: 0.0 ± 0.0
Gln
1.323GlnAla: 1.323 ± 0.755
0.0GlnCys: 0.0 ± 0.0
1.323GlnAsp: 1.323 ± 1.681
5.291GlnGlu: 5.291 ± 4.393
1.323GlnPhe: 1.323 ± 1.681
1.323GlnGly: 1.323 ± 1.681
0.0GlnHis: 0.0 ± 0.0
2.646GlnIle: 2.646 ± 4.207
3.968GlnLys: 3.968 ± 2.72
3.968GlnLeu: 3.968 ± 1.821
0.0GlnMet: 0.0 ± 0.0
1.323GlnAsn: 1.323 ± 0.755
5.291GlnPro: 5.291 ± 2.152
1.323GlnGln: 1.323 ± 1.681
3.968GlnArg: 3.968 ± 0.793
5.291GlnSer: 5.291 ± 1.113
5.291GlnThr: 5.291 ± 3.34
0.0GlnVal: 0.0 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
3.968GlnTyr: 3.968 ± 2.265
0.0GlnXaa: 0.0 ± 0.0
Arg
1.323ArgAla: 1.323 ± 0.755
0.0ArgCys: 0.0 ± 0.0
0.0ArgAsp: 0.0 ± 0.0
0.0ArgGlu: 0.0 ± 0.0
5.291ArgPhe: 5.291 ± 2.114
3.968ArgGly: 3.968 ± 2.265
3.968ArgHis: 3.968 ± 2.265
3.968ArgIle: 3.968 ± 2.265
5.291ArgLys: 5.291 ± 3.02
7.937ArgLeu: 7.937 ± 1.07
1.323ArgMet: 1.323 ± 1.681
0.0ArgAsn: 0.0 ± 0.0
9.259ArgPro: 9.259 ± 1.53
2.646ArgGln: 2.646 ± 1.076
19.841ArgArg: 19.841 ± 9.121
6.614ArgSer: 6.614 ± 1.733
6.614ArgThr: 6.614 ± 1.733
5.291ArgVal: 5.291 ± 1.475
2.646ArgTrp: 2.646 ± 1.51
3.968ArgTyr: 3.968 ± 2.265
0.0ArgXaa: 0.0 ± 0.0
Ser
2.646SerAla: 2.646 ± 1.51
0.0SerCys: 0.0 ± 0.0
3.968SerAsp: 3.968 ± 2.72
3.968SerGlu: 3.968 ± 2.72
3.968SerPhe: 3.968 ± 1.821
7.937SerGly: 7.937 ± 3.642
1.323SerHis: 1.323 ± 0.755
3.968SerIle: 3.968 ± 2.265
5.291SerLys: 5.291 ± 1.475
2.646SerLeu: 2.646 ± 1.076
0.0SerMet: 0.0 ± 0.0
2.646SerAsn: 2.646 ± 3.363
2.646SerPro: 2.646 ± 1.076
3.968SerGln: 3.968 ± 5.044
3.968SerArg: 3.968 ± 2.72
10.582SerSer: 10.582 ± 4.988
3.968SerThr: 3.968 ± 2.72
1.323SerVal: 1.323 ± 1.681
2.646SerTrp: 2.646 ± 1.51
2.646SerTyr: 2.646 ± 1.076
0.0SerXaa: 0.0 ± 0.0
Thr
5.291ThrAla: 5.291 ± 1.113
2.646ThrCys: 2.646 ± 1.51
6.614ThrAsp: 6.614 ± 2.601
1.323ThrGlu: 1.323 ± 0.755
1.323ThrPhe: 1.323 ± 0.755
5.291ThrGly: 5.291 ± 1.113
2.646ThrHis: 2.646 ± 1.51
1.323ThrIle: 1.323 ± 0.755
5.291ThrLys: 5.291 ± 2.114
3.968ThrLeu: 3.968 ± 4.094
0.0ThrMet: 0.0 ± 0.0
2.646ThrAsn: 2.646 ± 1.51
2.646ThrPro: 2.646 ± 3.363
7.937ThrGln: 7.937 ± 1.834
5.291ThrArg: 5.291 ± 1.113
2.646ThrSer: 2.646 ± 3.363
7.937ThrThr: 7.937 ± 1.585
2.646ThrVal: 2.646 ± 1.51
5.291ThrTrp: 5.291 ± 3.02
2.646ThrTyr: 2.646 ± 1.076
0.0ThrXaa: 0.0 ± 0.0
Val
1.323ValAla: 1.323 ± 0.755
0.0ValCys: 0.0 ± 0.0
0.0ValAsp: 0.0 ± 0.0
1.323ValGlu: 1.323 ± 0.755
0.0ValPhe: 0.0 ± 0.0
0.0ValGly: 0.0 ± 0.0
1.323ValHis: 1.323 ± 0.755
1.323ValIle: 1.323 ± 0.755
2.646ValLys: 2.646 ± 2.786
3.968ValLeu: 3.968 ± 4.094
0.0ValMet: 0.0 ± 0.0
1.323ValAsn: 1.323 ± 0.755
3.968ValPro: 3.968 ± 0.793
1.323ValGln: 1.323 ± 0.755
5.291ValArg: 5.291 ± 2.114
6.614ValSer: 6.614 ± 4.854
7.937ValThr: 7.937 ± 3.642
1.323ValVal: 1.323 ± 0.755
1.323ValTrp: 1.323 ± 0.755
1.323ValTyr: 1.323 ± 0.755
0.0ValXaa: 0.0 ± 0.0
Trp
2.646TrpAla: 2.646 ± 1.51
1.323TrpCys: 1.323 ± 0.755
1.323TrpAsp: 1.323 ± 1.681
3.968TrpGlu: 3.968 ± 0.793
3.968TrpPhe: 3.968 ± 2.265
2.646TrpGly: 2.646 ± 1.51
1.323TrpHis: 1.323 ± 0.755
0.0TrpIle: 0.0 ± 0.0
2.646TrpLys: 2.646 ± 1.076
2.646TrpLeu: 2.646 ± 1.51
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
5.291TrpArg: 5.291 ± 3.02
1.323TrpSer: 1.323 ± 2.104
1.323TrpThr: 1.323 ± 0.755
1.323TrpVal: 1.323 ± 0.755
2.646TrpTrp: 2.646 ± 1.817
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.323TyrAla: 1.323 ± 0.755
1.323TyrCys: 1.323 ± 2.104
3.968TyrAsp: 3.968 ± 2.265
1.323TyrGlu: 1.323 ± 0.755
1.323TyrPhe: 1.323 ± 0.755
0.0TyrGly: 0.0 ± 0.0
1.323TyrHis: 1.323 ± 1.681
5.291TyrIle: 5.291 ± 2.114
2.646TyrLys: 2.646 ± 1.51
6.614TyrLeu: 6.614 ± 1.733
1.323TyrMet: 1.323 ± 0.755
0.0TyrAsn: 0.0 ± 0.0
1.323TyrPro: 1.323 ± 1.681
2.646TyrGln: 2.646 ± 1.817
7.937TyrArg: 7.937 ± 2.425
1.323TyrSer: 1.323 ± 1.681
3.968TyrThr: 3.968 ± 2.265
1.323TyrVal: 1.323 ± 2.104
0.0TyrTrp: 0.0 ± 0.0
1.323TyrTyr: 1.323 ± 0.755
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (757 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski