Amino acid dipepetide frequency for Hubei tombus-like virus 6

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.44AlaAla: 4.44 ± 2.573
1.11AlaCys: 1.11 ± 1.145
3.33AlaAsp: 3.33 ± 2.258
3.33AlaGlu: 3.33 ± 1.315
5.549AlaPhe: 5.549 ± 2.261
3.33AlaGly: 3.33 ± 1.596
0.0AlaHis: 0.0 ± 0.0
7.769AlaIle: 7.769 ± 1.289
2.22AlaLys: 2.22 ± 2.29
7.769AlaLeu: 7.769 ± 1.027
3.33AlaMet: 3.33 ± 1.596
3.33AlaAsn: 3.33 ± 2.015
3.33AlaPro: 3.33 ± 1.596
1.11AlaGln: 1.11 ± 1.011
3.33AlaArg: 3.33 ± 0.623
3.33AlaSer: 3.33 ± 1.315
3.33AlaThr: 3.33 ± 0.623
4.44AlaVal: 4.44 ± 2.573
2.22AlaTrp: 2.22 ± 1.322
2.22AlaTyr: 2.22 ± 0.993
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.11CysAsp: 1.11 ± 1.145
0.0CysGlu: 0.0 ± 0.0
1.11CysPhe: 1.11 ± 0.731
1.11CysGly: 1.11 ± 0.731
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.11CysLys: 1.11 ± 1.145
1.11CysLeu: 1.11 ± 1.011
0.0CysMet: 0.0 ± 0.0
1.11CysAsn: 1.11 ± 1.145
2.22CysPro: 2.22 ± 2.021
1.11CysGln: 1.11 ± 0.731
1.11CysArg: 1.11 ± 0.731
2.22CysSer: 2.22 ± 1.462
1.11CysThr: 1.11 ± 0.731
2.22CysVal: 2.22 ± 1.462
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.549AspAla: 5.549 ± 2.329
1.11AspCys: 1.11 ± 0.731
2.22AspAsp: 2.22 ± 0.993
3.33AspGlu: 3.33 ± 1.315
1.11AspPhe: 1.11 ± 1.145
7.769AspGly: 7.769 ± 1.027
2.22AspHis: 2.22 ± 0.993
1.11AspIle: 1.11 ± 0.731
2.22AspLys: 2.22 ± 1.322
4.44AspLeu: 4.44 ± 0.31
1.11AspMet: 1.11 ± 0.731
1.11AspAsn: 1.11 ± 1.011
3.33AspPro: 3.33 ± 1.315
2.22AspGln: 2.22 ± 0.721
2.22AspArg: 2.22 ± 1.322
4.44AspSer: 4.44 ± 1.65
2.22AspThr: 2.22 ± 2.29
3.33AspVal: 3.33 ± 3.032
1.11AspTrp: 1.11 ± 0.731
2.22AspTyr: 2.22 ± 0.993
0.0AspXaa: 0.0 ± 0.0
Glu
2.22GluAla: 2.22 ± 2.29
1.11GluCys: 1.11 ± 0.731
3.33GluAsp: 3.33 ± 1.315
4.44GluGlu: 4.44 ± 1.986
4.44GluPhe: 4.44 ± 1.882
2.22GluGly: 2.22 ± 2.021
1.11GluHis: 1.11 ± 0.731
1.11GluIle: 1.11 ± 0.731
4.44GluLys: 4.44 ± 1.65
7.769GluLeu: 7.769 ± 1.027
1.11GluMet: 1.11 ± 1.264
1.11GluAsn: 1.11 ± 0.731
5.549GluPro: 5.549 ± 1.314
3.33GluGln: 3.33 ± 1.042
2.22GluArg: 2.22 ± 1.462
3.33GluSer: 3.33 ± 0.623
0.0GluThr: 0.0 ± 0.0
1.11GluVal: 1.11 ± 1.145
0.0GluTrp: 0.0 ± 0.0
2.22GluTyr: 2.22 ± 0.993
0.0GluXaa: 0.0 ± 0.0
Phe
4.44PheAla: 4.44 ± 1.697
2.22PheCys: 2.22 ± 0.721
6.659PheAsp: 6.659 ± 0.495
3.33PheGlu: 3.33 ± 2.193
1.11PhePhe: 1.11 ± 1.011
5.549PheGly: 5.549 ± 1.934
0.0PheHis: 0.0 ± 0.0
0.0PheIle: 0.0 ± 0.0
3.33PheLys: 3.33 ± 0.623
3.33PheLeu: 3.33 ± 1.315
1.11PheMet: 1.11 ± 0.731
2.22PheAsn: 2.22 ± 1.462
2.22PhePro: 2.22 ± 0.721
2.22PheGln: 2.22 ± 0.993
2.22PheArg: 2.22 ± 0.993
3.33PheSer: 3.33 ± 1.315
1.11PheThr: 1.11 ± 0.731
5.549PheVal: 5.549 ± 0.711
0.0PheTrp: 0.0 ± 0.0
1.11PheTyr: 1.11 ± 0.731
0.0PheXaa: 0.0 ± 0.0
Gly
2.22GlyAla: 2.22 ± 2.021
1.11GlyCys: 1.11 ± 1.145
4.44GlyAsp: 4.44 ± 1.442
2.22GlyGlu: 2.22 ± 0.721
2.22GlyPhe: 2.22 ± 0.721
7.769GlyGly: 7.769 ± 2.73
1.11GlyHis: 1.11 ± 0.731
2.22GlyIle: 2.22 ± 1.462
4.44GlyLys: 4.44 ± 1.442
4.44GlyLeu: 4.44 ± 1.65
2.22GlyMet: 2.22 ± 0.721
1.11GlyAsn: 1.11 ± 0.731
3.33GlyPro: 3.33 ± 0.623
4.44GlyGln: 4.44 ± 0.31
4.44GlyArg: 4.44 ± 1.986
3.33GlySer: 3.33 ± 2.057
5.549GlyThr: 5.549 ± 1.636
6.659GlyVal: 6.659 ± 1.246
1.11GlyTrp: 1.11 ± 0.731
3.33GlyTyr: 3.33 ± 1.042
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
1.11HisAsp: 1.11 ± 0.731
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
1.11HisIle: 1.11 ± 1.011
1.11HisLys: 1.11 ± 0.731
0.0HisLeu: 0.0 ± 0.0
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
1.11HisGln: 1.11 ± 0.731
0.0HisArg: 0.0 ± 0.0
1.11HisSer: 1.11 ± 0.731
3.33HisThr: 3.33 ± 1.315
1.11HisVal: 1.11 ± 0.731
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.44IleAla: 4.44 ± 2.573
0.0IleCys: 0.0 ± 0.0
3.33IleAsp: 3.33 ± 1.315
5.549IleGlu: 5.549 ± 0.711
1.11IlePhe: 1.11 ± 0.731
3.33IleGly: 3.33 ± 1.596
0.0IleHis: 0.0 ± 0.0
1.11IleIle: 1.11 ± 1.145
3.33IleLys: 3.33 ± 0.623
1.11IleLeu: 1.11 ± 1.011
1.11IleMet: 1.11 ± 0.731
5.549IleAsn: 5.549 ± 1.934
1.11IlePro: 1.11 ± 0.731
1.11IleGln: 1.11 ± 1.145
3.33IleArg: 3.33 ± 1.042
4.44IleSer: 4.44 ± 1.65
2.22IleThr: 2.22 ± 0.721
3.33IleVal: 3.33 ± 0.623
0.0IleTrp: 0.0 ± 0.0
3.33IleTyr: 3.33 ± 1.596
0.0IleXaa: 0.0 ± 0.0
Lys
3.33LysAla: 3.33 ± 0.623
2.22LysCys: 2.22 ± 0.721
5.549LysAsp: 5.549 ± 2.213
4.44LysGlu: 4.44 ± 1.442
5.549LysPhe: 5.549 ± 2.213
7.769LysGly: 7.769 ± 2.373
1.11LysHis: 1.11 ± 0.731
3.33LysIle: 3.33 ± 1.042
2.22LysLys: 2.22 ± 1.462
5.549LysLeu: 5.549 ± 2.213
1.11LysMet: 1.11 ± 0.869
2.22LysAsn: 2.22 ± 1.322
3.33LysPro: 3.33 ± 2.193
0.0LysGln: 0.0 ± 0.0
4.44LysArg: 4.44 ± 2.645
3.33LysSer: 3.33 ± 1.042
3.33LysThr: 3.33 ± 1.315
3.33LysVal: 3.33 ± 2.258
5.549LysTrp: 5.549 ± 2.827
3.33LysTyr: 3.33 ± 0.623
0.0LysXaa: 0.0 ± 0.0
Leu
8.879LeuAla: 8.879 ± 3.325
0.0LeuCys: 0.0 ± 0.0
4.44LeuAsp: 4.44 ± 1.65
5.549LeuGlu: 5.549 ± 2.534
4.44LeuPhe: 4.44 ± 0.31
5.549LeuGly: 5.549 ± 2.534
0.0LeuHis: 0.0 ± 0.0
3.33LeuIle: 3.33 ± 3.032
7.769LeuLys: 7.769 ± 3.923
5.549LeuLeu: 5.549 ± 2.534
3.33LeuMet: 3.33 ± 1.315
5.549LeuAsn: 5.549 ± 1.636
4.44LeuPro: 4.44 ± 0.31
1.11LeuGln: 1.11 ± 0.731
4.44LeuArg: 4.44 ± 1.882
5.549LeuSer: 5.549 ± 2.307
4.44LeuThr: 4.44 ± 2.958
4.44LeuVal: 4.44 ± 3.327
0.0LeuTrp: 0.0 ± 0.0
3.33LeuTyr: 3.33 ± 2.193
0.0LeuXaa: 0.0 ± 0.0
Met
3.33MetAla: 3.33 ± 1.042
3.33MetCys: 3.33 ± 1.042
1.11MetAsp: 1.11 ± 1.145
1.11MetGlu: 1.11 ± 0.731
1.11MetPhe: 1.11 ± 1.145
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
3.33MetIle: 3.33 ± 0.623
2.22MetLys: 2.22 ± 2.29
1.11MetLeu: 1.11 ± 0.731
1.11MetMet: 1.11 ± 1.145
2.22MetAsn: 2.22 ± 0.721
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
2.22MetArg: 2.22 ± 2.021
3.33MetSer: 3.33 ± 1.315
2.22MetThr: 2.22 ± 1.462
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
2.22MetTyr: 2.22 ± 0.993
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
1.11AsnCys: 1.11 ± 0.731
2.22AsnAsp: 2.22 ± 0.721
0.0AsnGlu: 0.0 ± 0.0
2.22AsnPhe: 2.22 ± 0.721
2.22AsnGly: 2.22 ± 0.721
0.0AsnHis: 0.0 ± 0.0
1.11AsnIle: 1.11 ± 0.731
3.33AsnLys: 3.33 ± 2.015
4.44AsnLeu: 4.44 ± 0.31
1.11AsnMet: 1.11 ± 0.731
1.11AsnAsn: 1.11 ± 0.731
3.33AsnPro: 3.33 ± 1.042
2.22AsnGln: 2.22 ± 1.322
1.11AsnArg: 1.11 ± 1.145
3.33AsnSer: 3.33 ± 1.042
2.22AsnThr: 2.22 ± 0.721
5.549AsnVal: 5.549 ± 1.314
1.11AsnTrp: 1.11 ± 1.011
2.22AsnTyr: 2.22 ± 1.322
0.0AsnXaa: 0.0 ± 0.0
Pro
6.659ProAla: 6.659 ± 2.578
0.0ProCys: 0.0 ± 0.0
3.33ProAsp: 3.33 ± 1.315
0.0ProGlu: 0.0 ± 0.0
1.11ProPhe: 1.11 ± 0.731
2.22ProGly: 2.22 ± 2.021
1.11ProHis: 1.11 ± 0.731
5.549ProIle: 5.549 ± 0.711
2.22ProLys: 2.22 ± 0.721
2.22ProLeu: 2.22 ± 0.721
2.22ProMet: 2.22 ± 2.29
0.0ProAsn: 0.0 ± 0.0
3.33ProPro: 3.33 ± 3.032
1.11ProGln: 1.11 ± 0.731
4.44ProArg: 4.44 ± 1.65
2.22ProSer: 2.22 ± 0.721
5.549ProThr: 5.549 ± 3.914
6.659ProVal: 6.659 ± 1.648
1.11ProTrp: 1.11 ± 0.731
2.22ProTyr: 2.22 ± 0.721
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
3.33GlnGlu: 3.33 ± 2.193
1.11GlnPhe: 1.11 ± 1.011
1.11GlnGly: 1.11 ± 1.145
1.11GlnHis: 1.11 ± 0.731
2.22GlnIle: 2.22 ± 1.462
3.33GlnLys: 3.33 ± 2.015
2.22GlnLeu: 2.22 ± 0.721
1.11GlnMet: 1.11 ± 1.145
1.11GlnAsn: 1.11 ± 1.011
2.22GlnPro: 2.22 ± 2.021
2.22GlnGln: 2.22 ± 0.721
6.659GlnArg: 6.659 ± 1.648
2.22GlnSer: 2.22 ± 1.322
2.22GlnThr: 2.22 ± 0.721
0.0GlnVal: 0.0 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
2.22GlnTyr: 2.22 ± 0.993
0.0GlnXaa: 0.0 ± 0.0
Arg
5.549ArgAla: 5.549 ± 0.934
0.0ArgCys: 0.0 ± 0.0
1.11ArgAsp: 1.11 ± 0.731
0.0ArgGlu: 0.0 ± 0.0
4.44ArgPhe: 4.44 ± 1.354
4.44ArgGly: 4.44 ± 1.442
0.0ArgHis: 0.0 ± 0.0
0.0ArgIle: 0.0 ± 0.0
7.769ArgLys: 7.769 ± 1.622
6.659ArgLeu: 6.659 ± 1.648
2.22ArgMet: 2.22 ± 0.993
4.44ArgAsn: 4.44 ± 0.31
2.22ArgPro: 2.22 ± 1.322
1.11ArgGln: 1.11 ± 0.731
2.22ArgArg: 2.22 ± 0.993
2.22ArgSer: 2.22 ± 0.993
2.22ArgThr: 2.22 ± 0.993
5.549ArgVal: 5.549 ± 0.711
3.33ArgTrp: 3.33 ± 1.596
2.22ArgTyr: 2.22 ± 0.721
0.0ArgXaa: 0.0 ± 0.0
Ser
3.33SerAla: 3.33 ± 0.623
2.22SerCys: 2.22 ± 1.462
3.33SerAsp: 3.33 ± 1.042
6.659SerGlu: 6.659 ± 1.246
3.33SerPhe: 3.33 ± 1.315
5.549SerGly: 5.549 ± 2.261
1.11SerHis: 1.11 ± 0.731
2.22SerIle: 2.22 ± 1.462
4.44SerLys: 4.44 ± 1.442
6.659SerLeu: 6.659 ± 1.648
3.33SerMet: 3.33 ± 0.623
2.22SerAsn: 2.22 ± 0.721
3.33SerPro: 3.33 ± 1.042
3.33SerGln: 3.33 ± 0.623
4.44SerArg: 4.44 ± 1.442
4.44SerSer: 4.44 ± 1.65
5.549SerThr: 5.549 ± 2.261
4.44SerVal: 4.44 ± 0.31
1.11SerTrp: 1.11 ± 1.011
1.11SerTyr: 1.11 ± 1.011
0.0SerXaa: 0.0 ± 0.0
Thr
4.44ThrAla: 4.44 ± 1.442
1.11ThrCys: 1.11 ± 1.145
3.33ThrAsp: 3.33 ± 0.623
2.22ThrGlu: 2.22 ± 0.993
1.11ThrPhe: 1.11 ± 1.145
3.33ThrGly: 3.33 ± 1.315
0.0ThrHis: 0.0 ± 0.0
4.44ThrIle: 4.44 ± 2.958
6.659ThrLys: 6.659 ± 1.283
0.0ThrLeu: 0.0 ± 0.0
1.11ThrMet: 1.11 ± 1.011
1.11ThrAsn: 1.11 ± 0.731
5.549ThrPro: 5.549 ± 0.711
0.0ThrGln: 0.0 ± 0.0
5.549ThrArg: 5.549 ± 0.711
4.44ThrSer: 4.44 ± 1.442
6.659ThrThr: 6.659 ± 2.876
6.659ThrVal: 6.659 ± 3.192
0.0ThrTrp: 0.0 ± 0.0
2.22ThrTyr: 2.22 ± 0.721
0.0ThrXaa: 0.0 ± 0.0
Val
7.769ValAla: 7.769 ± 3.405
0.0ValCys: 0.0 ± 0.0
1.11ValAsp: 1.11 ± 1.011
3.33ValGlu: 3.33 ± 2.258
8.879ValPhe: 8.879 ± 2.164
2.22ValGly: 2.22 ± 1.462
1.11ValHis: 1.11 ± 1.011
3.33ValIle: 3.33 ± 1.596
5.549ValLys: 5.549 ± 0.934
7.769ValLeu: 7.769 ± 3.586
2.22ValMet: 2.22 ± 0.661
1.11ValAsn: 1.11 ± 0.731
4.44ValPro: 4.44 ± 1.354
4.44ValGln: 4.44 ± 2.645
0.0ValArg: 0.0 ± 0.0
9.989ValSer: 9.989 ± 3.656
5.549ValThr: 5.549 ± 3.307
4.44ValVal: 4.44 ± 3.123
0.0ValTrp: 0.0 ± 0.0
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
1.11TrpAla: 1.11 ± 0.731
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
3.33TrpGlu: 3.33 ± 1.315
1.11TrpPhe: 1.11 ± 0.731
1.11TrpGly: 1.11 ± 1.145
0.0TrpHis: 0.0 ± 0.0
4.44TrpIle: 4.44 ± 1.697
0.0TrpLys: 0.0 ± 0.0
2.22TrpLeu: 2.22 ± 0.721
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.11TrpArg: 1.11 ± 1.011
1.11TrpSer: 1.11 ± 0.731
0.0TrpThr: 0.0 ± 0.0
2.22TrpVal: 2.22 ± 2.021
0.0TrpTrp: 0.0 ± 0.0
1.11TrpTyr: 1.11 ± 1.011
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.11TyrAla: 1.11 ± 1.011
0.0TyrCys: 0.0 ± 0.0
3.33TyrAsp: 3.33 ± 1.596
1.11TyrGlu: 1.11 ± 0.731
0.0TyrPhe: 0.0 ± 0.0
1.11TyrGly: 1.11 ± 0.731
0.0TyrHis: 0.0 ± 0.0
1.11TyrIle: 1.11 ± 1.145
3.33TyrLys: 3.33 ± 0.623
7.769TyrLeu: 7.769 ± 2.245
0.0TyrMet: 0.0 ± 0.0
3.33TyrAsn: 3.33 ± 0.623
0.0TyrPro: 0.0 ± 0.0
2.22TyrGln: 2.22 ± 1.462
2.22TyrArg: 2.22 ± 1.462
4.44TyrSer: 4.44 ± 2.573
1.11TyrThr: 1.11 ± 0.731
2.22TyrVal: 2.22 ± 1.322
2.22TyrTrp: 2.22 ± 1.462
1.11TyrTyr: 1.11 ± 0.731
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (902 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski