Amino acid dipepetide frequency for Pseudofulvimonas gallinarii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
17.572AlaAla: 17.572 ± 0.199
1.303AlaCys: 1.303 ± 0.039
7.671AlaAsp: 7.671 ± 0.088
6.856AlaGlu: 6.856 ± 0.1
3.955AlaPhe: 3.955 ± 0.077
12.354AlaGly: 12.354 ± 0.13
2.549AlaHis: 2.549 ± 0.06
5.432AlaIle: 5.432 ± 0.079
2.269AlaLys: 2.269 ± 0.055
15.054AlaLeu: 15.054 ± 0.168
3.187AlaMet: 3.187 ± 0.069
2.857AlaAsn: 2.857 ± 0.063
6.041AlaPro: 6.041 ± 0.099
4.983AlaGln: 4.983 ± 0.088
10.153AlaArg: 10.153 ± 0.134
6.566AlaSer: 6.566 ± 0.097
6.456AlaThr: 6.456 ± 0.103
9.112AlaVal: 9.112 ± 0.108
2.145AlaTrp: 2.145 ± 0.052
2.278AlaTyr: 2.278 ± 0.057
0.0AlaXaa: 0.0 ± 0.0
Cys
1.156CysAla: 1.156 ± 0.041
0.095CysCys: 0.095 ± 0.01
0.541CysAsp: 0.541 ± 0.025
0.476CysGlu: 0.476 ± 0.021
0.287CysPhe: 0.287 ± 0.018
0.945CysGly: 0.945 ± 0.031
0.296CysHis: 0.296 ± 0.023
0.363CysIle: 0.363 ± 0.018
0.132CysLys: 0.132 ± 0.012
0.92CysLeu: 0.92 ± 0.033
0.143CysMet: 0.143 ± 0.011
0.243CysAsn: 0.243 ± 0.016
0.485CysPro: 0.485 ± 0.025
0.261CysGln: 0.261 ± 0.017
0.716CysArg: 0.716 ± 0.033
0.524CysSer: 0.524 ± 0.024
0.523CysThr: 0.523 ± 0.023
0.633CysVal: 0.633 ± 0.026
0.121CysTrp: 0.121 ± 0.014
0.189CysTyr: 0.189 ± 0.015
0.0CysXaa: 0.0 ± 0.0
Asp
7.861AspAla: 7.861 ± 0.088
0.584AspCys: 0.584 ± 0.024
3.905AspAsp: 3.905 ± 0.077
3.384AspGlu: 3.384 ± 0.066
2.116AspPhe: 2.116 ± 0.047
6.58AspGly: 6.58 ± 0.115
1.338AspHis: 1.338 ± 0.04
2.798AspIle: 2.798 ± 0.051
1.067AspLys: 1.067 ± 0.034
6.017AspLeu: 6.017 ± 0.079
1.084AspMet: 1.084 ± 0.031
1.536AspAsn: 1.536 ± 0.044
3.875AspPro: 3.875 ± 0.076
1.698AspGln: 1.698 ± 0.039
4.613AspArg: 4.613 ± 0.071
2.924AspSer: 2.924 ± 0.058
2.79AspThr: 2.79 ± 0.06
4.348AspVal: 4.348 ± 0.063
1.161AspTrp: 1.161 ± 0.037
1.549AspTyr: 1.549 ± 0.04
0.0AspXaa: 0.0 ± 0.0
Glu
6.983GluAla: 6.983 ± 0.107
0.371GluCys: 0.371 ± 0.021
2.592GluAsp: 2.592 ± 0.052
2.345GluGlu: 2.345 ± 0.051
1.664GluPhe: 1.664 ± 0.039
4.342GluGly: 4.342 ± 0.063
1.357GluHis: 1.357 ± 0.039
2.374GluIle: 2.374 ± 0.055
1.21GluLys: 1.21 ± 0.042
6.263GluLeu: 6.263 ± 0.095
0.99GluMet: 0.99 ± 0.033
1.274GluAsn: 1.274 ± 0.038
2.624GluPro: 2.624 ± 0.057
2.436GluGln: 2.436 ± 0.051
5.571GluArg: 5.571 ± 0.099
2.686GluSer: 2.686 ± 0.05
2.557GluThr: 2.557 ± 0.054
3.811GluVal: 3.811 ± 0.063
0.693GluTrp: 0.693 ± 0.026
1.02GluTyr: 1.02 ± 0.033
0.0GluXaa: 0.0 ± 0.0
Phe
4.332PheAla: 4.332 ± 0.072
0.303PheCys: 0.303 ± 0.015
2.673PheAsp: 2.673 ± 0.057
2.1PheGlu: 2.1 ± 0.046
1.041PhePhe: 1.041 ± 0.031
3.156PheGly: 3.156 ± 0.059
0.802PheHis: 0.802 ± 0.026
1.298PheIle: 1.298 ± 0.038
0.672PheLys: 0.672 ± 0.028
2.997PheLeu: 2.997 ± 0.053
0.644PheMet: 0.644 ± 0.023
1.018PheAsn: 1.018 ± 0.035
1.501PhePro: 1.501 ± 0.041
1.091PheGln: 1.091 ± 0.034
2.413PheArg: 2.413 ± 0.045
1.991PheSer: 1.991 ± 0.053
1.835PheThr: 1.835 ± 0.054
2.4PheVal: 2.4 ± 0.058
0.482PheTrp: 0.482 ± 0.023
0.717PheTyr: 0.717 ± 0.025
0.0PheXaa: 0.0 ± 0.0
Gly
9.186GlyAla: 9.186 ± 0.115
0.943GlyCys: 0.943 ± 0.034
5.587GlyAsp: 5.587 ± 0.079
5.16GlyGlu: 5.16 ± 0.07
3.454GlyPhe: 3.454 ± 0.058
8.125GlyGly: 8.125 ± 0.165
2.39GlyHis: 2.39 ± 0.054
4.059GlyIle: 4.059 ± 0.08
2.315GlyLys: 2.315 ± 0.051
9.103GlyLeu: 9.103 ± 0.114
2.172GlyMet: 2.172 ± 0.048
2.992GlyAsn: 2.992 ± 0.089
3.434GlyPro: 3.434 ± 0.064
3.329GlyGln: 3.329 ± 0.061
7.186GlyArg: 7.186 ± 0.101
5.43GlySer: 5.43 ± 0.092
4.754GlyThr: 4.754 ± 0.105
6.405GlyVal: 6.405 ± 0.085
1.592GlyTrp: 1.592 ± 0.044
2.3GlyTyr: 2.3 ± 0.045
0.0GlyXaa: 0.0 ± 0.0
His
3.062HisAla: 3.062 ± 0.068
0.294HisCys: 0.294 ± 0.018
1.346HisAsp: 1.346 ± 0.037
1.158HisGlu: 1.158 ± 0.035
0.861HisPhe: 0.861 ± 0.031
2.413HisGly: 2.413 ± 0.055
0.6HisHis: 0.6 ± 0.031
0.859HisIle: 0.859 ± 0.028
0.343HisLys: 0.343 ± 0.019
2.321HisLeu: 2.321 ± 0.045
0.401HisMet: 0.401 ± 0.024
0.521HisAsn: 0.521 ± 0.022
1.579HisPro: 1.579 ± 0.042
0.632HisGln: 0.632 ± 0.024
1.871HisArg: 1.871 ± 0.053
1.024HisSer: 1.024 ± 0.03
0.95HisThr: 0.95 ± 0.029
1.744HisVal: 1.744 ± 0.04
0.457HisTrp: 0.457 ± 0.021
0.656HisTyr: 0.656 ± 0.029
0.001HisXaa: 0.001 ± 0.001
Ile
6.154IleAla: 6.154 ± 0.091
0.298IleCys: 0.298 ± 0.02
3.631IleAsp: 3.631 ± 0.052
3.242IleGlu: 3.242 ± 0.063
1.068IlePhe: 1.068 ± 0.03
4.35IleGly: 4.35 ± 0.066
0.969IleHis: 0.969 ± 0.032
1.392IleIle: 1.392 ± 0.038
0.877IleLys: 0.877 ± 0.034
3.391IleLeu: 3.391 ± 0.063
0.527IleMet: 0.527 ± 0.025
1.208IleAsn: 1.208 ± 0.036
1.863IlePro: 1.863 ± 0.044
1.256IleGln: 1.256 ± 0.04
2.971IleArg: 2.971 ± 0.057
2.07IleSer: 2.07 ± 0.049
2.036IleThr: 2.036 ± 0.06
3.231IleVal: 3.231 ± 0.063
0.487IleTrp: 0.487 ± 0.022
0.812IleTyr: 0.812 ± 0.03
0.0IleXaa: 0.0 ± 0.0
Lys
2.653LysAla: 2.653 ± 0.067
0.128LysCys: 0.128 ± 0.013
0.993LysAsp: 0.993 ± 0.034
0.883LysGlu: 0.883 ± 0.034
0.509LysPhe: 0.509 ± 0.022
1.483LysGly: 1.483 ± 0.048
0.39LysHis: 0.39 ± 0.022
0.807LysIle: 0.807 ± 0.035
0.645LysLys: 0.645 ± 0.047
2.2LysLeu: 2.2 ± 0.051
0.385LysMet: 0.385 ± 0.022
0.48LysAsn: 0.48 ± 0.023
1.421LysPro: 1.421 ± 0.044
0.742LysGln: 0.742 ± 0.03
1.758LysArg: 1.758 ± 0.046
1.072LysSer: 1.072 ± 0.038
1.042LysThr: 1.042 ± 0.035
1.677LysVal: 1.677 ± 0.044
0.215LysTrp: 0.215 ± 0.016
0.382LysTyr: 0.382 ± 0.022
0.0LysXaa: 0.0 ± 0.0
Leu
15.935LeuAla: 15.935 ± 0.185
0.941LeuCys: 0.941 ± 0.03
7.138LeuAsp: 7.138 ± 0.083
5.327LeuGlu: 5.327 ± 0.086
3.589LeuPhe: 3.589 ± 0.074
8.523LeuGly: 8.523 ± 0.114
2.446LeuHis: 2.446 ± 0.056
3.851LeuIle: 3.851 ± 0.075
2.364LeuLys: 2.364 ± 0.059
11.774LeuLeu: 11.774 ± 0.174
1.861LeuMet: 1.861 ± 0.045
2.221LeuAsn: 2.221 ± 0.051
6.741LeuPro: 6.741 ± 0.094
3.358LeuGln: 3.358 ± 0.063
9.599LeuArg: 9.599 ± 0.117
5.886LeuSer: 5.886 ± 0.08
4.73LeuThr: 4.73 ± 0.075
8.55LeuVal: 8.55 ± 0.109
1.321LeuTrp: 1.321 ± 0.046
2.189LeuTyr: 2.189 ± 0.053
0.0LeuXaa: 0.0 ± 0.0
Met
2.643MetAla: 2.643 ± 0.05
0.148MetCys: 0.148 ± 0.012
1.05MetAsp: 1.05 ± 0.034
0.903MetGlu: 0.903 ± 0.029
0.558MetPhe: 0.558 ± 0.026
1.4MetGly: 1.4 ± 0.036
0.418MetHis: 0.418 ± 0.02
0.807MetIle: 0.807 ± 0.032
0.629MetLys: 0.629 ± 0.027
2.202MetLeu: 2.202 ± 0.043
0.393MetMet: 0.393 ± 0.021
0.641MetAsn: 0.641 ± 0.025
1.34MetPro: 1.34 ± 0.042
0.802MetGln: 0.802 ± 0.028
1.719MetArg: 1.719 ± 0.038
1.454MetSer: 1.454 ± 0.037
1.263MetThr: 1.263 ± 0.032
1.472MetVal: 1.472 ± 0.038
0.174MetTrp: 0.174 ± 0.012
0.323MetTyr: 0.323 ± 0.016
0.0MetXaa: 0.0 ± 0.0
Asn
3.163AsnAla: 3.163 ± 0.056
0.264AsnCys: 0.264 ± 0.014
1.435AsnAsp: 1.435 ± 0.042
1.18AsnGlu: 1.18 ± 0.037
0.804AsnPhe: 0.804 ± 0.034
2.765AsnGly: 2.765 ± 0.076
0.548AsnHis: 0.548 ± 0.024
1.095AsnIle: 1.095 ± 0.037
0.436AsnLys: 0.436 ± 0.021
2.449AsnLeu: 2.449 ± 0.053
0.435AsnMet: 0.435 ± 0.021
0.828AsnAsn: 0.828 ± 0.041
1.689AsnPro: 1.689 ± 0.054
0.807AsnGln: 0.807 ± 0.034
1.883AsnArg: 1.883 ± 0.045
1.196AsnSer: 1.196 ± 0.045
1.35AsnThr: 1.35 ± 0.046
1.782AsnVal: 1.782 ± 0.045
0.434AsnTrp: 0.434 ± 0.025
0.651AsnTyr: 0.651 ± 0.028
0.0AsnXaa: 0.0 ± 0.0
Pro
7.94ProAla: 7.94 ± 0.109
0.38ProCys: 0.38 ± 0.023
4.215ProAsp: 4.215 ± 0.074
3.293ProGlu: 3.293 ± 0.056
1.62ProPhe: 1.62 ± 0.037
5.46ProGly: 5.46 ± 0.084
1.085ProHis: 1.085 ± 0.035
1.66ProIle: 1.66 ± 0.043
0.898ProLys: 0.898 ± 0.03
5.117ProLeu: 5.117 ± 0.079
1.297ProMet: 1.297 ± 0.035
1.069ProAsn: 1.069 ± 0.04
2.99ProPro: 2.99 ± 0.07
1.779ProGln: 1.779 ± 0.044
3.545ProArg: 3.545 ± 0.075
2.877ProSer: 2.877 ± 0.06
2.367ProThr: 2.367 ± 0.05
4.735ProVal: 4.735 ± 0.066
0.878ProTrp: 0.878 ± 0.03
1.112ProTyr: 1.112 ± 0.033
0.0ProXaa: 0.0 ± 0.0
Gln
5.369GlnAla: 5.369 ± 0.097
0.277GlnCys: 0.277 ± 0.018
1.445GlnAsp: 1.445 ± 0.036
1.332GlnGlu: 1.332 ± 0.039
1.12GlnPhe: 1.12 ± 0.03
2.712GlnGly: 2.712 ± 0.059
0.829GlnHis: 0.829 ± 0.032
1.414GlnIle: 1.414 ± 0.039
0.588GlnLys: 0.588 ± 0.029
3.819GlnLeu: 3.819 ± 0.066
0.701GlnMet: 0.701 ± 0.027
0.662GlnAsn: 0.662 ± 0.028
2.384GlnPro: 2.384 ± 0.046
1.424GlnGln: 1.424 ± 0.039
3.751GlnArg: 3.751 ± 0.074
1.647GlnSer: 1.647 ± 0.041
1.469GlnThr: 1.469 ± 0.036
2.989GlnVal: 2.989 ± 0.056
0.573GlnTrp: 0.573 ± 0.024
0.663GlnTyr: 0.663 ± 0.025
0.0GlnXaa: 0.0 ± 0.0
Arg
8.973ArgAla: 8.973 ± 0.121
0.737ArgCys: 0.737 ± 0.032
4.86ArgAsp: 4.86 ± 0.081
4.942ArgGlu: 4.942 ± 0.092
3.317ArgPhe: 3.317 ± 0.06
5.818ArgGly: 5.818 ± 0.074
2.301ArgHis: 2.301 ± 0.057
4.343ArgIle: 4.343 ± 0.063
1.682ArgLys: 1.682 ± 0.047
9.838ArgLeu: 9.838 ± 0.139
1.942ArgMet: 1.942 ± 0.046
2.109ArgAsn: 2.109 ± 0.047
3.988ArgPro: 3.988 ± 0.071
3.27ArgGln: 3.27 ± 0.067
7.287ArgArg: 7.287 ± 0.128
4.211ArgSer: 4.211 ± 0.064
3.389ArgThr: 3.389 ± 0.061
5.664ArgVal: 5.664 ± 0.084
1.443ArgTrp: 1.443 ± 0.044
2.135ArgTyr: 2.135 ± 0.051
0.0ArgXaa: 0.0 ± 0.0
Ser
6.456SerAla: 6.456 ± 0.086
0.46SerCys: 0.46 ± 0.022
2.935SerAsp: 2.935 ± 0.053
2.552SerGlu: 2.552 ± 0.052
1.789SerPhe: 1.789 ± 0.045
5.965SerGly: 5.965 ± 0.11
1.156SerHis: 1.156 ± 0.037
2.323SerIle: 2.323 ± 0.054
0.952SerLys: 0.952 ± 0.036
5.634SerLeu: 5.634 ± 0.082
1.116SerMet: 1.116 ± 0.033
1.452SerAsn: 1.452 ± 0.05
3.022SerPro: 3.022 ± 0.062
1.672SerGln: 1.672 ± 0.038
4.168SerArg: 4.168 ± 0.072
3.023SerSer: 3.023 ± 0.065
2.775SerThr: 2.775 ± 0.05
3.781SerVal: 3.781 ± 0.066
0.861SerTrp: 0.861 ± 0.033
1.098SerTyr: 1.098 ± 0.037
0.001SerXaa: 0.001 ± 0.001
Thr
5.984ThrAla: 5.984 ± 0.096
0.51ThrCys: 0.51 ± 0.03
2.465ThrAsp: 2.465 ± 0.056
1.911ThrGlu: 1.911 ± 0.05
1.631ThrPhe: 1.631 ± 0.049
5.22ThrGly: 5.22 ± 0.092
1.012ThrHis: 1.012 ± 0.037
2.083ThrIle: 2.083 ± 0.061
0.614ThrLys: 0.614 ± 0.027
5.981ThrLeu: 5.981 ± 0.086
0.852ThrMet: 0.852 ± 0.034
0.966ThrAsn: 0.966 ± 0.036
3.396ThrPro: 3.396 ± 0.064
1.432ThrGln: 1.432 ± 0.036
3.678ThrArg: 3.678 ± 0.068
2.478ThrSer: 2.478 ± 0.06
2.595ThrThr: 2.595 ± 0.066
4.176ThrVal: 4.176 ± 0.089
0.779ThrTrp: 0.779 ± 0.03
1.005ThrTyr: 1.005 ± 0.032
0.0ThrXaa: 0.0 ± 0.0
Val
9.658ValAla: 9.658 ± 0.114
0.643ValCys: 0.643 ± 0.026
4.793ValAsp: 4.793 ± 0.078
4.542ValGlu: 4.542 ± 0.065
2.653ValPhe: 2.653 ± 0.045
5.448ValGly: 5.448 ± 0.087
1.726ValHis: 1.726 ± 0.038
3.434ValIle: 3.434 ± 0.054
1.504ValLys: 1.504 ± 0.043
8.459ValLeu: 8.459 ± 0.116
1.496ValMet: 1.496 ± 0.041
2.038ValAsn: 2.038 ± 0.053
4.032ValPro: 4.032 ± 0.068
2.523ValGln: 2.523 ± 0.051
5.666ValArg: 5.666 ± 0.08
4.041ValSer: 4.041 ± 0.063
3.912ValThr: 3.912 ± 0.087
6.084ValVal: 6.084 ± 0.107
0.887ValTrp: 0.887 ± 0.034
1.539ValTyr: 1.539 ± 0.044
0.0ValXaa: 0.0 ± 0.0
Trp
1.246TrpAla: 1.246 ± 0.033
0.16TrpCys: 0.16 ± 0.014
0.63TrpAsp: 0.63 ± 0.024
0.482TrpGlu: 0.482 ± 0.019
0.612TrpPhe: 0.612 ± 0.027
0.821TrpGly: 0.821 ± 0.03
0.423TrpHis: 0.423 ± 0.023
0.688TrpIle: 0.688 ± 0.025
0.29TrpLys: 0.29 ± 0.018
2.54TrpLeu: 2.54 ± 0.062
0.372TrpMet: 0.372 ± 0.021
0.506TrpAsn: 0.506 ± 0.024
0.867TrpPro: 0.867 ± 0.033
0.881TrpGln: 0.881 ± 0.032
1.574TrpArg: 1.574 ± 0.047
0.902TrpSer: 0.902 ± 0.033
0.798TrpThr: 0.798 ± 0.034
0.918TrpVal: 0.918 ± 0.027
0.285TrpTrp: 0.285 ± 0.018
0.382TrpTyr: 0.382 ± 0.021
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.468TyrAla: 2.468 ± 0.056
0.208TyrCys: 0.208 ± 0.014
1.326TyrAsp: 1.326 ± 0.042
1.098TyrGlu: 1.098 ± 0.034
0.815TyrPhe: 0.815 ± 0.027
2.037TyrGly: 2.037 ± 0.045
0.457TyrHis: 0.457 ± 0.022
0.753TyrIle: 0.753 ± 0.027
0.378TyrLys: 0.378 ± 0.02
2.264TyrLeu: 2.264 ± 0.053
0.34TyrMet: 0.34 ± 0.017
0.575TyrAsn: 0.575 ± 0.025
1.047TyrPro: 1.047 ± 0.035
0.792TyrGln: 0.792 ± 0.026
2.127TyrArg: 2.127 ± 0.047
1.188TyrSer: 1.188 ± 0.033
1.172TyrThr: 1.172 ± 0.039
1.569TyrVal: 1.569 ± 0.045
0.387TyrTrp: 0.387 ± 0.021
0.563TyrTyr: 0.563 ± 0.026
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.001XaaAla: 0.001 ± 0.001
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.001XaaMet: 0.001 ± 0.001
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.001XaaXaa: 0.001 ± 0.001
Statistics based on 2887 proteins (1021112 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski