Amino acid dipepetide frequency for Catenovulum maritimum

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.766AlaAla: 6.766 ± 0.101	0.93AlaCys: 0.93 ± 0.025	4.913AlaAsp: 4.913 ± 0.068	5.991AlaGlu: 5.991 ± 0.093	3.178AlaPhe: 3.178 ± 0.048	5.318AlaGly: 5.318 ± 0.081	1.413AlaHis: 1.413 ± 0.032	5.861AlaIle: 5.861 ± 0.082	5.508AlaLys: 5.508 ± 0.08	8.221AlaLeu: 8.221 ± 0.088	1.937AlaMet: 1.937 ± 0.047	4.316AlaAsn: 4.316 ± 0.066	2.426AlaPro: 2.426 ± 0.053	3.656AlaGln: 3.656 ± 0.056	2.873AlaArg: 2.873 ± 0.049	5.361AlaSer: 5.361 ± 0.072	4.121AlaThr: 4.121 ± 0.063	5.0AlaVal: 5.0 ± 0.071	0.909AlaTrp: 0.909 ± 0.027	2.523AlaTyr: 2.523 ± 0.053	0.0AlaXaa: 0.0 ± 0.0
Cys	0.671CysAla: 0.671 ± 0.025	0.137CysCys: 0.137 ± 0.011	0.516CysAsp: 0.516 ± 0.021	0.552CysGlu: 0.552 ± 0.02	0.504CysPhe: 0.504 ± 0.02	0.733CysGly: 0.733 ± 0.025	0.309CysHis: 0.309 ± 0.019	0.627CysIle: 0.627 ± 0.023	0.448CysLys: 0.448 ± 0.018	1.033CysLeu: 1.033 ± 0.035	0.185CysMet: 0.185 ± 0.013	0.361CysAsn: 0.361 ± 0.018	0.404CysPro: 0.404 ± 0.02	0.501CysGln: 0.501 ± 0.023	0.391CysArg: 0.391 ± 0.017	0.657CysSer: 0.657 ± 0.024	0.394CysThr: 0.394 ± 0.02	0.559CysVal: 0.559 ± 0.021	0.096CysTrp: 0.096 ± 0.008	0.312CysTyr: 0.312 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	4.214AspAla: 4.214 ± 0.067	0.546AspCys: 0.546 ± 0.02	3.195AspAsp: 3.195 ± 0.081	3.803AspGlu: 3.803 ± 0.073	2.864AspPhe: 2.864 ± 0.045	3.749AspGly: 3.749 ± 0.08	0.972AspHis: 0.972 ± 0.028	4.429AspIle: 4.429 ± 0.067	4.002AspLys: 4.002 ± 0.059	5.859AspLeu: 5.859 ± 0.079	1.282AspMet: 1.282 ± 0.037	3.067AspAsn: 3.067 ± 0.051	1.93AspPro: 1.93 ± 0.048	1.973AspGln: 1.973 ± 0.042	1.869AspArg: 1.869 ± 0.038	3.908AspSer: 3.908 ± 0.071	3.056AspThr: 3.056 ± 0.063	3.565AspVal: 3.565 ± 0.067	0.973AspTrp: 0.973 ± 0.031	2.299AspTyr: 2.299 ± 0.049	0.0AspXaa: 0.0 ± 0.0
Glu	4.843GluAla: 4.843 ± 0.075	0.444GluCys: 0.444 ± 0.02	2.802GluAsp: 2.802 ± 0.061	3.288GluGlu: 3.288 ± 0.077	2.898GluPhe: 2.898 ± 0.053	2.876GluGly: 2.876 ± 0.051	1.397GluHis: 1.397 ± 0.034	4.733GluIle: 4.733 ± 0.064	4.033GluLys: 4.033 ± 0.073	7.308GluLeu: 7.308 ± 0.099	1.418GluMet: 1.418 ± 0.036	3.377GluAsn: 3.377 ± 0.062	1.815GluPro: 1.815 ± 0.044	4.058GluGln: 4.058 ± 0.076	2.376GluArg: 2.376 ± 0.05	3.998GluSer: 3.998 ± 0.068	3.492GluThr: 3.492 ± 0.058	3.925GluVal: 3.925 ± 0.064	0.709GluTrp: 0.709 ± 0.024	2.128GluTyr: 2.128 ± 0.042	0.0GluXaa: 0.0 ± 0.0
Phe	3.304PheAla: 3.304 ± 0.056	0.483PheCys: 0.483 ± 0.021	3.067PheAsp: 3.067 ± 0.06	2.887PheGlu: 2.887 ± 0.049	1.753PhePhe: 1.753 ± 0.044	2.966PheGly: 2.966 ± 0.056	0.801PheHis: 0.801 ± 0.027	3.126PheIle: 3.126 ± 0.062	2.697PheLys: 2.697 ± 0.053	3.317PheLeu: 3.317 ± 0.054	0.941PheMet: 0.941 ± 0.033	2.676PheAsn: 2.676 ± 0.049	1.373PhePro: 1.373 ± 0.032	1.431PheGln: 1.431 ± 0.035	1.417PheArg: 1.417 ± 0.034	3.824PheSer: 3.824 ± 0.061	2.504PheThr: 2.504 ± 0.048	2.7PheVal: 2.7 ± 0.052	0.593PheTrp: 0.593 ± 0.021	1.597PheTyr: 1.597 ± 0.038	0.0PheXaa: 0.0 ± 0.0
Gly	4.39GlyAla: 4.39 ± 0.075	0.749GlyCys: 0.749 ± 0.028	3.607GlyAsp: 3.607 ± 0.069	4.022GlyGlu: 4.022 ± 0.056	3.157GlyPhe: 3.157 ± 0.056	4.247GlyGly: 4.247 ± 0.081	1.344GlyHis: 1.344 ± 0.036	4.502GlyIle: 4.502 ± 0.072	4.047GlyLys: 4.047 ± 0.062	6.436GlyLeu: 6.436 ± 0.086	1.521GlyMet: 1.521 ± 0.037	2.786GlyAsn: 2.786 ± 0.056	1.451GlyPro: 1.451 ± 0.038	2.705GlyGln: 2.705 ± 0.053	2.512GlyArg: 2.512 ± 0.054	3.782GlySer: 3.782 ± 0.068	3.226GlyThr: 3.226 ± 0.067	4.429GlyVal: 4.429 ± 0.067	0.918GlyTrp: 0.918 ± 0.037	2.601GlyTyr: 2.601 ± 0.057	0.0GlyXaa: 0.0 ± 0.0
His	1.378HisAla: 1.378 ± 0.034	0.254HisCys: 0.254 ± 0.013	1.018HisAsp: 1.018 ± 0.027	1.021HisGlu: 1.021 ± 0.031	1.033HisPhe: 1.033 ± 0.032	1.379HisGly: 1.379 ± 0.041	0.545HisHis: 0.545 ± 0.022	1.413HisIle: 1.413 ± 0.032	1.31HisLys: 1.31 ± 0.034	2.095HisLeu: 2.095 ± 0.045	0.447HisMet: 0.447 ± 0.018	1.002HisAsn: 1.002 ± 0.029	0.986HisPro: 0.986 ± 0.031	1.137HisGln: 1.137 ± 0.031	0.794HisArg: 0.794 ± 0.027	1.44HisSer: 1.44 ± 0.035	1.029HisThr: 1.029 ± 0.031	1.088HisVal: 1.088 ± 0.032	0.354HisTrp: 0.354 ± 0.018	0.856HisTyr: 0.856 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	6.139IleAla: 6.139 ± 0.075	0.768IleCys: 0.768 ± 0.027	4.68IleAsp: 4.68 ± 0.063	5.333IleGlu: 5.333 ± 0.068	2.618IlePhe: 2.618 ± 0.056	4.414IleGly: 4.414 ± 0.073	1.312IleHis: 1.312 ± 0.034	4.119IleIle: 4.119 ± 0.066	4.822IleLys: 4.822 ± 0.072	5.816IleLeu: 5.816 ± 0.08	1.206IleMet: 1.206 ± 0.032	4.059IleAsn: 4.059 ± 0.065	2.6IlePro: 2.6 ± 0.047	2.842IleGln: 2.842 ± 0.059	2.694IleArg: 2.694 ± 0.051	5.606IleSer: 5.606 ± 0.073	3.88IleThr: 3.88 ± 0.068	3.967IleVal: 3.967 ± 0.071	0.748IleTrp: 0.748 ± 0.027	2.076IleTyr: 2.076 ± 0.045	0.0IleXaa: 0.0 ± 0.0
Lys	5.197LysAla: 5.197 ± 0.083	0.393LysCys: 0.393 ± 0.022	3.071LysAsp: 3.071 ± 0.05	3.124LysGlu: 3.124 ± 0.064	2.286LysPhe: 2.286 ± 0.046	3.243LysGly: 3.243 ± 0.056	1.506LysHis: 1.506 ± 0.045	4.373LysIle: 4.373 ± 0.069	3.503LysLys: 3.503 ± 0.064	7.108LysLeu: 7.108 ± 0.1	1.471LysMet: 1.471 ± 0.03	3.068LysAsn: 3.068 ± 0.06	2.813LysPro: 2.813 ± 0.055	3.925LysGln: 3.925 ± 0.073	2.575LysArg: 2.575 ± 0.047	3.982LysSer: 3.982 ± 0.061	3.562LysThr: 3.562 ± 0.052	4.136LysVal: 4.136 ± 0.065	0.716LysTrp: 0.716 ± 0.022	1.937LysTyr: 1.937 ± 0.048	0.0LysXaa: 0.0 ± 0.0
Leu	9.65LeuAla: 9.65 ± 0.117	0.866LeuCys: 0.866 ± 0.028	6.207LeuAsp: 6.207 ± 0.084	5.962LeuGlu: 5.962 ± 0.088	4.111LeuPhe: 4.111 ± 0.077	6.042LeuGly: 6.042 ± 0.076	1.741LeuHis: 1.741 ± 0.037	7.073LeuIle: 7.073 ± 0.099	6.333LeuLys: 6.333 ± 0.09	9.039LeuLeu: 9.039 ± 0.126	2.173LeuMet: 2.173 ± 0.043	5.849LeuAsn: 5.849 ± 0.076	4.181LeuPro: 4.181 ± 0.055	3.258LeuGln: 3.258 ± 0.067	3.341LeuArg: 3.341 ± 0.061	7.954LeuSer: 7.954 ± 0.084	6.545LeuThr: 6.545 ± 0.079	6.792LeuVal: 6.792 ± 0.082	0.964LeuTrp: 0.964 ± 0.028	2.771LeuTyr: 2.771 ± 0.056	0.0LeuXaa: 0.0 ± 0.0
Met	1.922MetAla: 1.922 ± 0.042	0.153MetCys: 0.153 ± 0.012	1.048MetAsp: 1.048 ± 0.03	1.01MetGlu: 1.01 ± 0.032	0.883MetPhe: 0.883 ± 0.031	1.373MetGly: 1.373 ± 0.036	0.429MetHis: 0.429 ± 0.017	1.237MetIle: 1.237 ± 0.037	1.372MetLys: 1.372 ± 0.033	2.327MetLeu: 2.327 ± 0.048	0.54MetMet: 0.54 ± 0.021	1.031MetAsn: 1.031 ± 0.03	1.096MetPro: 1.096 ± 0.03	1.11MetGln: 1.11 ± 0.032	0.914MetArg: 0.914 ± 0.033	1.708MetSer: 1.708 ± 0.038	1.374MetThr: 1.374 ± 0.032	1.319MetVal: 1.319 ± 0.037	0.184MetTrp: 0.184 ± 0.013	0.504MetTyr: 0.504 ± 0.02	0.0MetXaa: 0.0 ± 0.0
Asn	3.733AsnAla: 3.733 ± 0.055	0.486AsnCys: 0.486 ± 0.021	2.651AsnAsp: 2.651 ± 0.059	2.741AsnGlu: 2.741 ± 0.058	2.193AsnPhe: 2.193 ± 0.048	3.314AsnGly: 3.314 ± 0.072	1.112AsnHis: 1.112 ± 0.028	3.604AsnIle: 3.604 ± 0.053	3.416AsnLys: 3.416 ± 0.058	5.684AsnLeu: 5.684 ± 0.074	1.124AsnMet: 1.124 ± 0.028	2.894AsnAsn: 2.894 ± 0.058	2.341AsnPro: 2.341 ± 0.054	3.44AsnGln: 3.44 ± 0.07	2.022AsnArg: 2.022 ± 0.044	3.462AsnSer: 3.462 ± 0.077	2.795AsnThr: 2.795 ± 0.055	2.765AsnVal: 2.765 ± 0.054	0.843AsnTrp: 0.843 ± 0.029	1.822AsnTyr: 1.822 ± 0.038	0.0AsnXaa: 0.0 ± 0.0
Pro	2.8ProAla: 2.8 ± 0.051	0.279ProCys: 0.279 ± 0.016	2.382ProAsp: 2.382 ± 0.046	3.181ProGlu: 3.181 ± 0.052	1.548ProPhe: 1.548 ± 0.036	1.9ProGly: 1.9 ± 0.05	0.778ProHis: 0.778 ± 0.025	2.623ProIle: 2.623 ± 0.043	2.233ProLys: 2.233 ± 0.045	3.249ProLeu: 3.249 ± 0.053	0.792ProMet: 0.792 ± 0.028	2.195ProAsn: 2.195 ± 0.042	0.949ProPro: 0.949 ± 0.033	1.345ProGln: 1.345 ± 0.04	1.07ProArg: 1.07 ± 0.026	2.565ProSer: 2.565 ± 0.048	1.935ProThr: 1.935 ± 0.04	2.639ProVal: 2.639 ± 0.048	0.479ProTrp: 0.479 ± 0.019	1.271ProTyr: 1.271 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	4.988GlnAla: 4.988 ± 0.072	0.308GlnCys: 0.308 ± 0.016	2.353GlnAsp: 2.353 ± 0.044	2.157GlnGlu: 2.157 ± 0.044	2.089GlnPhe: 2.089 ± 0.043	2.856GlnGly: 2.856 ± 0.047	1.097GlnHis: 1.097 ± 0.033	3.444GlnIle: 3.444 ± 0.055	2.565GlnLys: 2.565 ± 0.056	5.242GlnLeu: 5.242 ± 0.087	0.94GlnMet: 0.94 ± 0.032	2.356GlnAsn: 2.356 ± 0.051	1.533GlnPro: 1.533 ± 0.04	3.119GlnGln: 3.119 ± 0.086	1.699GlnArg: 1.699 ± 0.037	3.039GlnSer: 3.039 ± 0.059	2.842GlnThr: 2.842 ± 0.052	3.472GlnVal: 3.472 ± 0.057	0.526GlnTrp: 0.526 ± 0.021	1.547GlnTyr: 1.547 ± 0.033	0.0GlnXaa: 0.0 ± 0.0
Arg	2.753ArgAla: 2.753 ± 0.048	0.324ArgCys: 0.324 ± 0.019	2.043ArgAsp: 2.043 ± 0.041	2.207ArgGlu: 2.207 ± 0.053	1.966ArgPhe: 1.966 ± 0.039	2.157ArgGly: 2.157 ± 0.044	0.893ArgHis: 0.893 ± 0.029	2.653ArgIle: 2.653 ± 0.053	2.199ArgLys: 2.199 ± 0.043	4.014ArgLeu: 4.014 ± 0.058	0.888ArgMet: 0.888 ± 0.029	1.762ArgAsn: 1.762 ± 0.037	1.385ArgPro: 1.385 ± 0.04	1.798ArgGln: 1.798 ± 0.04	1.622ArgArg: 1.622 ± 0.043	2.214ArgSer: 2.214 ± 0.044	1.7ArgThr: 1.7 ± 0.038	2.662ArgVal: 2.662 ± 0.051	0.529ArgTrp: 0.529 ± 0.02	1.531ArgTyr: 1.531 ± 0.035	0.0ArgXaa: 0.0 ± 0.0
Ser	5.618SerAla: 5.618 ± 0.073	0.704SerCys: 0.704 ± 0.025	4.083SerAsp: 4.083 ± 0.073	4.348SerGlu: 4.348 ± 0.065	3.32SerPhe: 3.32 ± 0.059	4.975SerGly: 4.975 ± 0.082	1.473SerHis: 1.473 ± 0.034	5.035SerIle: 5.035 ± 0.078	3.86SerLys: 3.86 ± 0.063	7.491SerLeu: 7.491 ± 0.091	1.395SerMet: 1.395 ± 0.033	3.496SerAsn: 3.496 ± 0.066	2.323SerPro: 2.323 ± 0.041	3.413SerGln: 3.413 ± 0.056	2.611SerArg: 2.611 ± 0.048	4.888SerSer: 4.888 ± 0.082	3.499SerThr: 3.499 ± 0.054	4.656SerVal: 4.656 ± 0.059	0.874SerTrp: 0.874 ± 0.035	2.308SerTyr: 2.308 ± 0.045	0.0SerXaa: 0.0 ± 0.0
Thr	4.618ThrAla: 4.618 ± 0.081	0.453ThrCys: 0.453 ± 0.02	3.427ThrAsp: 3.427 ± 0.065	3.671ThrGlu: 3.671 ± 0.058	2.078ThrPhe: 2.078 ± 0.047	4.239ThrGly: 4.239 ± 0.076	1.145ThrHis: 1.145 ± 0.033	3.52ThrIle: 3.52 ± 0.066	3.08ThrLys: 3.08 ± 0.053	5.408ThrLeu: 5.408 ± 0.078	0.923ThrMet: 0.923 ± 0.027	2.711ThrAsn: 2.711 ± 0.053	2.578ThrPro: 2.578 ± 0.045	2.777ThrGln: 2.777 ± 0.051	1.978ThrArg: 1.978 ± 0.042	3.888ThrSer: 3.888 ± 0.073	2.94ThrThr: 2.94 ± 0.068	3.259ThrVal: 3.259 ± 0.071	0.701ThrTrp: 0.701 ± 0.023	1.671ThrTyr: 1.671 ± 0.041	0.0ThrXaa: 0.0 ± 0.0
Val	5.104ValAla: 5.104 ± 0.074	0.625ValCys: 0.625 ± 0.024	3.947ValAsp: 3.947 ± 0.07	4.523ValGlu: 4.523 ± 0.07	2.7ValPhe: 2.7 ± 0.046	3.863ValGly: 3.863 ± 0.072	1.088ValHis: 1.088 ± 0.032	4.569ValIle: 4.569 ± 0.063	4.141ValLys: 4.141 ± 0.07	5.871ValLeu: 5.871 ± 0.067	1.433ValMet: 1.433 ± 0.036	3.454ValAsn: 3.454 ± 0.052	2.201ValPro: 2.201 ± 0.047	2.088ValGln: 2.088 ± 0.041	2.343ValArg: 2.343 ± 0.047	4.993ValSer: 4.993 ± 0.066	3.923ValThr: 3.923 ± 0.082	4.361ValVal: 4.361 ± 0.065	0.724ValTrp: 0.724 ± 0.026	1.966ValTyr: 1.966 ± 0.045	0.0ValXaa: 0.0 ± 0.0
Trp	0.765TrpAla: 0.765 ± 0.026	0.137TrpCys: 0.137 ± 0.011	0.642TrpAsp: 0.642 ± 0.026	0.492TrpGlu: 0.492 ± 0.023	0.653TrpPhe: 0.653 ± 0.023	0.758TrpGly: 0.758 ± 0.031	0.41TrpHis: 0.41 ± 0.018	0.692TrpIle: 0.692 ± 0.026	0.547TrpLys: 0.547 ± 0.022	1.688TrpLeu: 1.688 ± 0.046	0.276TrpMet: 0.276 ± 0.016	0.489TrpAsn: 0.489 ± 0.021	0.441TrpPro: 0.441 ± 0.02	1.135TrpGln: 1.135 ± 0.034	0.665TrpArg: 0.665 ± 0.023	0.811TrpSer: 0.811 ± 0.031	0.53TrpThr: 0.53 ± 0.025	0.802TrpVal: 0.802 ± 0.025	0.173TrpTrp: 0.173 ± 0.013	0.424TrpTyr: 0.424 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.369TyrAla: 2.369 ± 0.048	0.35TyrCys: 0.35 ± 0.019	1.904TyrAsp: 1.904 ± 0.046	1.605TyrGlu: 1.605 ± 0.038	1.624TyrPhe: 1.624 ± 0.037	2.034TyrGly: 2.034 ± 0.046	0.812TyrHis: 0.812 ± 0.026	2.061TyrIle: 2.061 ± 0.041	1.871TyrLys: 1.871 ± 0.045	3.647TyrLeu: 3.647 ± 0.059	0.641TyrMet: 0.641 ± 0.024	1.492TyrAsn: 1.492 ± 0.033	1.387TyrPro: 1.387 ± 0.031	2.463TyrGln: 2.463 ± 0.052	1.534TyrArg: 1.534 ± 0.039	2.289TyrSer: 2.289 ± 0.039	1.718TyrThr: 1.718 ± 0.04	1.821TyrVal: 1.821 ± 0.047	0.516TyrTrp: 0.516 ± 0.021	1.233TyrTyr: 1.233 ± 0.037	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3470 proteins (1245000 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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