Amino acid dipepetide frequency for Oenococcus phage vB_OeS_unk162

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.835AlaAla: 5.835 ± 1.256
0.087AlaCys: 0.087 ± 0.091
3.832AlaAsp: 3.832 ± 0.4
2.874AlaGlu: 2.874 ± 0.475
2.438AlaPhe: 2.438 ± 0.503
2.7AlaGly: 2.7 ± 0.606
0.261AlaHis: 0.261 ± 0.13
4.79AlaIle: 4.79 ± 0.678
5.312AlaLys: 5.312 ± 1.292
5.138AlaLeu: 5.138 ± 1.038
1.742AlaMet: 1.742 ± 0.359
4.093AlaAsn: 4.093 ± 0.706
2.351AlaPro: 2.351 ± 0.375
3.658AlaGln: 3.658 ± 0.709
2.003AlaArg: 2.003 ± 0.546
7.925AlaSer: 7.925 ± 1.315
5.922AlaThr: 5.922 ± 1.093
5.051AlaVal: 5.051 ± 0.701
1.306AlaTrp: 1.306 ± 0.295
2.264AlaTyr: 2.264 ± 0.383
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.348CysAsp: 0.348 ± 0.129
0.174CysGlu: 0.174 ± 0.113
0.348CysPhe: 0.348 ± 0.26
0.0CysGly: 0.0 ± 0.0
0.174CysHis: 0.174 ± 0.13
0.174CysIle: 0.174 ± 0.167
0.261CysLys: 0.261 ± 0.231
0.348CysLeu: 0.348 ± 0.214
0.261CysMet: 0.261 ± 0.122
0.087CysAsn: 0.087 ± 0.103
0.087CysPro: 0.087 ± 0.096
0.087CysGln: 0.087 ± 0.077
0.087CysArg: 0.087 ± 0.096
0.174CysSer: 0.174 ± 0.102
0.261CysThr: 0.261 ± 0.133
0.087CysVal: 0.087 ± 0.089
0.087CysTrp: 0.087 ± 0.097
0.435CysTyr: 0.435 ± 0.174
0.0CysXaa: 0.0 ± 0.0
Asp
2.874AspAla: 2.874 ± 0.416
0.261AspCys: 0.261 ± 0.162
5.661AspAsp: 5.661 ± 0.891
5.051AspGlu: 5.051 ± 0.971
3.483AspPhe: 3.483 ± 0.474
4.703AspGly: 4.703 ± 0.548
1.393AspHis: 1.393 ± 0.416
5.748AspIle: 5.748 ± 0.641
5.399AspLys: 5.399 ± 0.939
5.835AspLeu: 5.835 ± 0.725
1.48AspMet: 1.48 ± 0.48
5.051AspAsn: 5.051 ± 0.763
2.351AspPro: 2.351 ± 0.393
2.613AspGln: 2.613 ± 0.486
2.525AspArg: 2.525 ± 0.609
5.486AspSer: 5.486 ± 0.557
4.616AspThr: 4.616 ± 0.762
4.093AspVal: 4.093 ± 0.702
1.48AspTrp: 1.48 ± 0.37
2.874AspTyr: 2.874 ± 0.421
0.0AspXaa: 0.0 ± 0.0
Glu
3.396GluAla: 3.396 ± 0.588
0.348GluCys: 0.348 ± 0.155
2.874GluAsp: 2.874 ± 0.48
3.309GluGlu: 3.309 ± 0.976
2.525GluPhe: 2.525 ± 0.495
2.09GluGly: 2.09 ± 0.436
0.697GluHis: 0.697 ± 0.209
5.399GluIle: 5.399 ± 1.062
4.441GluLys: 4.441 ± 0.786
5.486GluLeu: 5.486 ± 0.879
1.393GluMet: 1.393 ± 0.338
4.441GluAsn: 4.441 ± 0.628
1.306GluPro: 1.306 ± 0.43
3.048GluGln: 3.048 ± 0.628
1.829GluArg: 1.829 ± 0.536
2.7GluSer: 2.7 ± 0.754
2.613GluThr: 2.613 ± 0.437
3.048GluVal: 3.048 ± 0.401
0.348GluTrp: 0.348 ± 0.221
1.568GluTyr: 1.568 ± 0.384
0.0GluXaa: 0.0 ± 0.0
Phe
2.264PheAla: 2.264 ± 0.402
0.174PheCys: 0.174 ± 0.126
4.18PheAsp: 4.18 ± 0.748
2.264PheGlu: 2.264 ± 0.424
1.568PhePhe: 1.568 ± 0.368
2.961PheGly: 2.961 ± 0.516
0.784PheHis: 0.784 ± 0.261
2.351PheIle: 2.351 ± 0.371
3.048PheLys: 3.048 ± 1.067
2.787PheLeu: 2.787 ± 0.51
1.393PheMet: 1.393 ± 0.497
3.658PheAsn: 3.658 ± 0.56
0.784PhePro: 0.784 ± 0.224
1.655PheGln: 1.655 ± 0.354
1.393PheArg: 1.393 ± 0.375
3.135PheSer: 3.135 ± 0.474
4.093PheThr: 4.093 ± 1.009
2.525PheVal: 2.525 ± 0.552
0.174PheTrp: 0.174 ± 0.108
2.09PheTyr: 2.09 ± 0.362
0.0PheXaa: 0.0 ± 0.0
Gly
4.18GlyAla: 4.18 ± 0.923
0.087GlyCys: 0.087 ± 0.078
3.919GlyAsp: 3.919 ± 0.735
2.264GlyGlu: 2.264 ± 0.459
2.525GlyPhe: 2.525 ± 0.465
3.745GlyGly: 3.745 ± 0.802
1.132GlyHis: 1.132 ± 0.273
5.312GlyIle: 5.312 ± 1.157
4.441GlyLys: 4.441 ± 0.976
4.964GlyLeu: 4.964 ± 0.66
1.306GlyMet: 1.306 ± 0.393
3.832GlyAsn: 3.832 ± 0.7
0.261GlyPro: 0.261 ± 0.133
2.177GlyGln: 2.177 ± 0.457
2.003GlyArg: 2.003 ± 0.599
5.748GlySer: 5.748 ± 1.183
6.793GlyThr: 6.793 ± 1.415
3.745GlyVal: 3.745 ± 0.594
0.697GlyTrp: 0.697 ± 0.211
3.048GlyTyr: 3.048 ± 0.642
0.0GlyXaa: 0.0 ± 0.0
His
0.348HisAla: 0.348 ± 0.158
0.087HisCys: 0.087 ± 0.103
1.045HisAsp: 1.045 ± 0.233
1.132HisGlu: 1.132 ± 0.367
1.306HisPhe: 1.306 ± 0.413
0.784HisGly: 0.784 ± 0.267
0.523HisHis: 0.523 ± 0.184
0.958HisIle: 0.958 ± 0.323
1.655HisLys: 1.655 ± 0.535
0.523HisLeu: 0.523 ± 0.212
0.261HisMet: 0.261 ± 0.149
0.871HisAsn: 0.871 ± 0.285
0.784HisPro: 0.784 ± 0.355
0.261HisGln: 0.261 ± 0.141
0.697HisArg: 0.697 ± 0.264
1.219HisSer: 1.219 ± 0.352
0.784HisThr: 0.784 ± 0.158
0.958HisVal: 0.958 ± 0.3
0.261HisTrp: 0.261 ± 0.118
0.871HisTyr: 0.871 ± 0.33
0.0HisXaa: 0.0 ± 0.0
Ile
4.441IleAla: 4.441 ± 0.601
0.348IleCys: 0.348 ± 0.189
6.967IleAsp: 6.967 ± 0.691
4.616IleGlu: 4.616 ± 0.812
2.7IlePhe: 2.7 ± 0.491
5.225IleGly: 5.225 ± 0.98
1.219IleHis: 1.219 ± 0.294
6.357IleIle: 6.357 ± 0.919
6.531IleLys: 6.531 ± 1.108
3.832IleLeu: 3.832 ± 0.555
0.871IleMet: 0.871 ± 0.229
4.441IleAsn: 4.441 ± 0.627
2.09IlePro: 2.09 ± 0.337
3.832IleGln: 3.832 ± 0.526
2.264IleArg: 2.264 ± 0.517
6.706IleSer: 6.706 ± 0.662
5.051IleThr: 5.051 ± 1.29
3.745IleVal: 3.745 ± 0.684
1.132IleTrp: 1.132 ± 0.314
2.525IleTyr: 2.525 ± 0.558
0.0IleXaa: 0.0 ± 0.0
Lys
5.138LysAla: 5.138 ± 0.92
0.087LysCys: 0.087 ± 0.083
6.531LysAsp: 6.531 ± 1.476
3.658LysGlu: 3.658 ± 0.891
3.309LysPhe: 3.309 ± 0.45
3.309LysGly: 3.309 ± 1.09
1.045LysHis: 1.045 ± 0.398
4.964LysIle: 4.964 ± 0.758
6.706LysLys: 6.706 ± 1.424
6.096LysLeu: 6.096 ± 1.139
2.874LysMet: 2.874 ± 0.774
6.096LysAsn: 6.096 ± 0.99
2.787LysPro: 2.787 ± 0.535
3.222LysGln: 3.222 ± 0.661
2.003LysArg: 2.003 ± 0.575
3.832LysSer: 3.832 ± 1.199
5.922LysThr: 5.922 ± 0.827
4.267LysVal: 4.267 ± 0.708
0.784LysTrp: 0.784 ± 0.231
3.309LysTyr: 3.309 ± 0.772
0.0LysXaa: 0.0 ± 0.0
Leu
5.661LeuAla: 5.661 ± 0.782
0.261LeuCys: 0.261 ± 0.157
4.616LeuAsp: 4.616 ± 0.803
4.877LeuGlu: 4.877 ± 0.839
3.396LeuPhe: 3.396 ± 0.561
5.225LeuGly: 5.225 ± 0.893
0.871LeuHis: 0.871 ± 0.304
4.703LeuIle: 4.703 ± 0.532
7.664LeuLys: 7.664 ± 1.667
4.006LeuLeu: 4.006 ± 0.639
1.568LeuMet: 1.568 ± 0.415
4.441LeuAsn: 4.441 ± 0.694
1.916LeuPro: 1.916 ± 0.39
2.351LeuGln: 2.351 ± 0.332
2.351LeuArg: 2.351 ± 0.575
5.835LeuSer: 5.835 ± 0.779
6.618LeuThr: 6.618 ± 0.851
3.309LeuVal: 3.309 ± 0.41
0.871LeuTrp: 0.871 ± 0.295
2.438LeuTyr: 2.438 ± 0.453
0.0LeuXaa: 0.0 ± 0.0
Met
1.916MetAla: 1.916 ± 0.471
0.0MetCys: 0.0 ± 0.0
1.655MetAsp: 1.655 ± 0.357
0.871MetGlu: 0.871 ± 0.284
1.568MetPhe: 1.568 ± 0.439
0.697MetGly: 0.697 ± 0.219
0.0MetHis: 0.0 ± 0.0
1.219MetIle: 1.219 ± 0.353
2.351MetLys: 2.351 ± 0.512
1.916MetLeu: 1.916 ± 0.387
0.174MetMet: 0.174 ± 0.123
0.958MetAsn: 0.958 ± 0.251
0.697MetPro: 0.697 ± 0.198
0.61MetGln: 0.61 ± 0.26
0.61MetArg: 0.61 ± 0.251
1.916MetSer: 1.916 ± 0.389
3.658MetThr: 3.658 ± 0.571
0.697MetVal: 0.697 ± 0.243
0.435MetTrp: 0.435 ± 0.199
0.435MetTyr: 0.435 ± 0.157
0.0MetXaa: 0.0 ± 0.0
Asn
5.225AsnAla: 5.225 ± 0.844
0.348AsnCys: 0.348 ± 0.163
4.616AsnAsp: 4.616 ± 0.515
2.874AsnGlu: 2.874 ± 0.583
2.177AsnPhe: 2.177 ± 0.378
5.399AsnGly: 5.399 ± 0.774
1.132AsnHis: 1.132 ± 0.267
5.225AsnIle: 5.225 ± 0.532
3.832AsnLys: 3.832 ± 0.859
4.964AsnLeu: 4.964 ± 0.643
0.784AsnMet: 0.784 ± 0.246
5.573AsnAsn: 5.573 ± 0.613
2.351AsnPro: 2.351 ± 0.497
2.613AsnGln: 2.613 ± 0.39
1.045AsnArg: 1.045 ± 0.438
5.486AsnSer: 5.486 ± 0.903
4.528AsnThr: 4.528 ± 0.687
3.135AsnVal: 3.135 ± 0.421
1.132AsnTrp: 1.132 ± 0.233
2.961AsnTyr: 2.961 ± 0.574
0.0AsnXaa: 0.0 ± 0.0
Pro
2.264ProAla: 2.264 ± 0.362
0.0ProCys: 0.0 ± 0.0
3.135ProAsp: 3.135 ± 0.579
1.916ProGlu: 1.916 ± 0.598
0.958ProPhe: 0.958 ± 0.311
0.697ProGly: 0.697 ± 0.189
0.61ProHis: 0.61 ± 0.319
2.787ProIle: 2.787 ± 0.495
2.177ProLys: 2.177 ± 0.423
2.09ProLeu: 2.09 ± 0.458
0.174ProMet: 0.174 ± 0.099
1.393ProAsn: 1.393 ± 0.316
0.261ProPro: 0.261 ± 0.142
0.784ProGln: 0.784 ± 0.24
0.784ProArg: 0.784 ± 0.333
1.916ProSer: 1.916 ± 0.312
1.829ProThr: 1.829 ± 0.452
1.916ProVal: 1.916 ± 0.501
0.174ProTrp: 0.174 ± 0.103
1.916ProTyr: 1.916 ± 0.351
0.0ProXaa: 0.0 ± 0.0
Gln
2.961GlnAla: 2.961 ± 0.611
0.348GlnCys: 0.348 ± 0.165
2.09GlnAsp: 2.09 ± 0.379
2.438GlnGlu: 2.438 ± 0.436
2.177GlnPhe: 2.177 ± 0.656
1.045GlnGly: 1.045 ± 0.224
0.523GlnHis: 0.523 ± 0.204
4.616GlnIle: 4.616 ± 0.651
3.396GlnLys: 3.396 ± 0.77
2.787GlnLeu: 2.787 ± 0.498
1.48GlnMet: 1.48 ± 0.393
2.438GlnAsn: 2.438 ± 0.413
1.219GlnPro: 1.219 ± 0.268
2.177GlnGln: 2.177 ± 0.586
0.958GlnArg: 0.958 ± 0.334
3.57GlnSer: 3.57 ± 0.475
3.483GlnThr: 3.483 ± 0.48
3.135GlnVal: 3.135 ± 0.648
0.435GlnTrp: 0.435 ± 0.17
1.829GlnTyr: 1.829 ± 0.391
0.0GlnXaa: 0.0 ± 0.0
Arg
1.568ArgAla: 1.568 ± 0.432
0.261ArgCys: 0.261 ± 0.162
1.132ArgAsp: 1.132 ± 0.401
0.958ArgGlu: 0.958 ± 0.329
1.306ArgPhe: 1.306 ± 0.346
1.306ArgGly: 1.306 ± 0.263
0.871ArgHis: 0.871 ± 0.39
2.525ArgIle: 2.525 ± 0.547
2.264ArgLys: 2.264 ± 0.606
2.874ArgLeu: 2.874 ± 0.632
0.958ArgMet: 0.958 ± 0.351
1.655ArgAsn: 1.655 ± 0.542
0.523ArgPro: 0.523 ± 0.218
1.829ArgGln: 1.829 ± 0.59
0.697ArgArg: 0.697 ± 0.299
1.393ArgSer: 1.393 ± 0.323
1.393ArgThr: 1.393 ± 0.414
1.48ArgVal: 1.48 ± 0.382
0.435ArgTrp: 0.435 ± 0.277
1.568ArgTyr: 1.568 ± 0.338
0.0ArgXaa: 0.0 ± 0.0
Ser
8.012SerAla: 8.012 ± 2.143
0.261SerCys: 0.261 ± 0.129
6.793SerAsp: 6.793 ± 1.075
3.919SerGlu: 3.919 ± 0.626
3.57SerPhe: 3.57 ± 0.473
7.054SerGly: 7.054 ± 1.71
0.697SerHis: 0.697 ± 0.237
4.79SerIle: 4.79 ± 0.554
5.486SerLys: 5.486 ± 1.036
6.096SerLeu: 6.096 ± 0.931
1.655SerMet: 1.655 ± 0.303
4.616SerAsn: 4.616 ± 0.744
1.829SerPro: 1.829 ± 0.342
3.483SerGln: 3.483 ± 0.603
1.132SerArg: 1.132 ± 0.348
8.97SerSer: 8.97 ± 2.03
5.922SerThr: 5.922 ± 0.813
4.79SerVal: 4.79 ± 0.597
0.697SerTrp: 0.697 ± 0.244
1.829SerTyr: 1.829 ± 0.342
0.0SerXaa: 0.0 ± 0.0
Thr
6.27ThrAla: 6.27 ± 0.894
0.261ThrCys: 0.261 ± 0.117
5.486ThrAsp: 5.486 ± 0.501
3.483ThrGlu: 3.483 ± 0.48
3.048ThrPhe: 3.048 ± 0.508
7.402ThrGly: 7.402 ± 1.562
1.48ThrHis: 1.48 ± 0.328
6.706ThrIle: 6.706 ± 0.964
3.832ThrLys: 3.832 ± 0.66
4.441ThrLeu: 4.441 ± 0.791
1.306ThrMet: 1.306 ± 0.334
4.267ThrAsn: 4.267 ± 0.682
2.613ThrPro: 2.613 ± 0.508
3.57ThrGln: 3.57 ± 0.681
1.742ThrArg: 1.742 ± 0.431
6.444ThrSer: 6.444 ± 1.369
5.835ThrThr: 5.835 ± 1.243
5.661ThrVal: 5.661 ± 1.331
1.306ThrTrp: 1.306 ± 0.375
2.874ThrTyr: 2.874 ± 0.628
0.0ThrXaa: 0.0 ± 0.0
Val
4.267ValAla: 4.267 ± 0.754
0.087ValCys: 0.087 ± 0.096
3.745ValAsp: 3.745 ± 0.448
2.787ValGlu: 2.787 ± 0.58
2.874ValPhe: 2.874 ± 0.33
4.964ValGly: 4.964 ± 0.73
0.871ValHis: 0.871 ± 0.254
4.18ValIle: 4.18 ± 0.635
3.57ValLys: 3.57 ± 0.588
3.309ValLeu: 3.309 ± 0.493
1.219ValMet: 1.219 ± 0.306
4.093ValAsn: 4.093 ± 0.642
2.177ValPro: 2.177 ± 0.485
2.09ValGln: 2.09 ± 0.367
1.393ValArg: 1.393 ± 0.364
4.877ValSer: 4.877 ± 0.958
4.616ValThr: 4.616 ± 0.95
3.483ValVal: 3.483 ± 0.49
0.697ValTrp: 0.697 ± 0.225
2.961ValTyr: 2.961 ± 0.49
0.0ValXaa: 0.0 ± 0.0
Trp
0.697TrpAla: 0.697 ± 0.264
0.0TrpCys: 0.0 ± 0.0
1.655TrpAsp: 1.655 ± 0.348
0.523TrpGlu: 0.523 ± 0.195
0.435TrpPhe: 0.435 ± 0.224
0.61TrpGly: 0.61 ± 0.265
0.348TrpHis: 0.348 ± 0.208
0.348TrpIle: 0.348 ± 0.139
1.045TrpLys: 1.045 ± 0.411
1.568TrpLeu: 1.568 ± 0.288
0.087TrpMet: 0.087 ± 0.103
1.48TrpAsn: 1.48 ± 0.64
0.174TrpPro: 0.174 ± 0.099
0.784TrpGln: 0.784 ± 0.297
0.174TrpArg: 0.174 ± 0.136
0.871TrpSer: 0.871 ± 0.28
0.871TrpThr: 0.871 ± 0.269
1.219TrpVal: 1.219 ± 0.317
0.087TrpTrp: 0.087 ± 0.087
0.174TrpTyr: 0.174 ± 0.108
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.264TyrAla: 2.264 ± 0.498
0.174TyrCys: 0.174 ± 0.132
2.7TyrAsp: 2.7 ± 0.709
2.874TyrGlu: 2.874 ± 0.615
1.568TyrPhe: 1.568 ± 0.414
2.264TyrGly: 2.264 ± 0.46
0.697TyrHis: 0.697 ± 0.228
1.829TyrIle: 1.829 ± 0.374
2.525TyrLys: 2.525 ± 0.501
3.919TyrLeu: 3.919 ± 0.592
1.306TyrMet: 1.306 ± 0.331
1.916TyrAsn: 1.916 ± 0.543
1.219TyrPro: 1.219 ± 0.388
2.264TyrGln: 2.264 ± 0.506
1.306TyrArg: 1.306 ± 0.415
3.396TyrSer: 3.396 ± 0.449
3.222TyrThr: 3.222 ± 0.754
1.916TyrVal: 1.916 ± 0.325
0.61TyrTrp: 0.61 ± 0.183
1.829TyrTyr: 1.829 ± 0.509
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 51 proteins (11484 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski