Amino acid dipepetide frequency for Leeuwenhoekiella blandensis (strain CECT 7118 / CCUG 51940 / MED217) (Flavobacterium sp. (strain MED217))

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.774AlaAla: 5.774 ± 0.086
0.56AlaCys: 0.56 ± 0.023
3.95AlaAsp: 3.95 ± 0.076
5.168AlaGlu: 5.168 ± 0.067
3.809AlaPhe: 3.809 ± 0.055
4.867AlaGly: 4.867 ± 0.066
1.286AlaHis: 1.286 ± 0.035
5.522AlaIle: 5.522 ± 0.084
4.659AlaLys: 4.659 ± 0.076
7.712AlaLeu: 7.712 ± 0.1
1.663AlaMet: 1.663 ± 0.042
3.448AlaAsn: 3.448 ± 0.054
2.311AlaPro: 2.311 ± 0.043
3.466AlaGln: 3.466 ± 0.057
2.55AlaArg: 2.55 ± 0.05
4.833AlaSer: 4.833 ± 0.068
4.133AlaThr: 4.133 ± 0.085
4.814AlaVal: 4.814 ± 0.074
0.728AlaTrp: 0.728 ± 0.023
3.057AlaTyr: 3.057 ± 0.046
0.0AlaXaa: 0.0 ± 0.0
Cys
0.46CysAla: 0.46 ± 0.02
0.099CysCys: 0.099 ± 0.009
0.408CysAsp: 0.408 ± 0.021
0.436CysGlu: 0.436 ± 0.024
0.351CysPhe: 0.351 ± 0.018
0.542CysGly: 0.542 ± 0.024
0.13CysHis: 0.13 ± 0.011
0.497CysIle: 0.497 ± 0.019
0.416CysLys: 0.416 ± 0.019
0.616CysLeu: 0.616 ± 0.02
0.128CysMet: 0.128 ± 0.01
0.3CysAsn: 0.3 ± 0.017
0.277CysPro: 0.277 ± 0.017
0.19CysGln: 0.19 ± 0.013
0.183CysArg: 0.183 ± 0.013
0.458CysSer: 0.458 ± 0.02
0.368CysThr: 0.368 ± 0.017
0.411CysVal: 0.411 ± 0.015
0.062CysTrp: 0.062 ± 0.007
0.265CysTyr: 0.265 ± 0.016
0.0CysXaa: 0.0 ± 0.0
Asp
4.599AspAla: 4.599 ± 0.094
0.351AspCys: 0.351 ± 0.015
3.058AspAsp: 3.058 ± 0.078
3.876AspGlu: 3.876 ± 0.066
3.73AspPhe: 3.73 ± 0.064
4.051AspGly: 4.051 ± 0.095
1.019AspHis: 1.019 ± 0.03
3.856AspIle: 3.856 ± 0.059
3.481AspLys: 3.481 ± 0.06
5.777AspLeu: 5.777 ± 0.078
1.097AspMet: 1.097 ± 0.031
2.624AspAsn: 2.624 ± 0.063
2.081AspPro: 2.081 ± 0.048
2.154AspGln: 2.154 ± 0.042
2.283AspArg: 2.283 ± 0.045
3.201AspSer: 3.201 ± 0.06
2.999AspThr: 2.999 ± 0.063
3.583AspVal: 3.583 ± 0.061
0.847AspTrp: 0.847 ± 0.029
2.859AspTyr: 2.859 ± 0.05
0.0AspXaa: 0.0 ± 0.0
Glu
5.868GluAla: 5.868 ± 0.086
0.27GluCys: 0.27 ± 0.017
4.132GluAsp: 4.132 ± 0.06
5.757GluGlu: 5.757 ± 0.071
2.771GluPhe: 2.771 ± 0.042
4.174GluGly: 4.174 ± 0.067
1.341GluHis: 1.341 ± 0.033
4.92GluIle: 4.92 ± 0.072
4.99GluLys: 4.99 ± 0.082
6.558GluLeu: 6.558 ± 0.071
1.555GluMet: 1.555 ± 0.033
4.267GluAsn: 4.267 ± 0.07
1.862GluPro: 1.862 ± 0.041
2.848GluGln: 2.848 ± 0.048
2.998GluArg: 2.998 ± 0.047
3.324GluSer: 3.324 ± 0.048
4.036GluThr: 4.036 ± 0.058
4.87GluVal: 4.87 ± 0.068
0.619GluTrp: 0.619 ± 0.023
2.524GluTyr: 2.524 ± 0.054
0.0GluXaa: 0.0 ± 0.0
Phe
3.224PheAla: 3.224 ± 0.052
0.411PheCys: 0.411 ± 0.018
3.373PheAsp: 3.373 ± 0.058
3.616PheGlu: 3.616 ± 0.06
2.617PhePhe: 2.617 ± 0.046
3.451PheGly: 3.451 ± 0.061
0.717PheHis: 0.717 ± 0.023
3.453PheIle: 3.453 ± 0.064
3.746PheLys: 3.746 ± 0.064
4.636PheLeu: 4.636 ± 0.076
1.141PheMet: 1.141 ± 0.028
2.967PheAsn: 2.967 ± 0.055
1.7PhePro: 1.7 ± 0.037
1.623PheGln: 1.623 ± 0.039
1.636PheArg: 1.636 ± 0.033
3.722PheSer: 3.722 ± 0.063
3.107PheThr: 3.107 ± 0.059
2.863PheVal: 2.863 ± 0.046
0.598PheTrp: 0.598 ± 0.023
2.175PheTyr: 2.175 ± 0.044
0.0PheXaa: 0.0 ± 0.0
Gly
4.808GlyAla: 4.808 ± 0.07
0.515GlyCys: 0.515 ± 0.022
3.631GlyAsp: 3.631 ± 0.085
3.66GlyGlu: 3.66 ± 0.052
3.719GlyPhe: 3.719 ± 0.057
4.61GlyGly: 4.61 ± 0.08
1.145GlyHis: 1.145 ± 0.036
5.173GlyIle: 5.173 ± 0.059
4.584GlyLys: 4.584 ± 0.083
6.122GlyLeu: 6.122 ± 0.078
1.567GlyMet: 1.567 ± 0.041
3.494GlyAsn: 3.494 ± 0.067
1.446GlyPro: 1.446 ± 0.038
1.997GlyGln: 1.997 ± 0.043
2.319GlyArg: 2.319 ± 0.045
4.154GlySer: 4.154 ± 0.073
4.079GlyThr: 4.079 ± 0.089
4.431GlyVal: 4.431 ± 0.063
0.843GlyTrp: 0.843 ± 0.032
2.902GlyTyr: 2.902 ± 0.047
0.0GlyXaa: 0.0 ± 0.0
His
1.004HisAla: 1.004 ± 0.031
0.164HisCys: 0.164 ± 0.011
0.793HisAsp: 0.793 ± 0.027
0.957HisGlu: 0.957 ± 0.029
1.149HisPhe: 1.149 ± 0.032
1.034HisGly: 1.034 ± 0.031
0.456HisHis: 0.456 ± 0.019
1.323HisIle: 1.323 ± 0.036
1.194HisLys: 1.194 ± 0.036
1.924HisLeu: 1.924 ± 0.044
0.356HisMet: 0.356 ± 0.019
0.927HisAsn: 0.927 ± 0.029
0.903HisPro: 0.903 ± 0.028
0.8HisGln: 0.8 ± 0.026
0.672HisArg: 0.672 ± 0.024
1.007HisSer: 1.007 ± 0.028
1.004HisThr: 1.004 ± 0.029
0.882HisVal: 0.882 ± 0.029
0.237HisTrp: 0.237 ± 0.016
0.89HisTyr: 0.89 ± 0.027
0.0HisXaa: 0.0 ± 0.0
Ile
5.776IleAla: 5.776 ± 0.074
0.511IleCys: 0.511 ± 0.021
4.553IleAsp: 4.553 ± 0.066
5.004IleGlu: 5.004 ± 0.068
3.02IlePhe: 3.02 ± 0.059
4.397IleGly: 4.397 ± 0.076
1.213IleHis: 1.213 ± 0.03
4.538IleIle: 4.538 ± 0.079
4.844IleLys: 4.844 ± 0.072
6.644IleLeu: 6.644 ± 0.1
1.112IleMet: 1.112 ± 0.03
3.971IleAsn: 3.971 ± 0.06
3.19IlePro: 3.19 ± 0.044
2.483IleGln: 2.483 ± 0.049
2.486IleArg: 2.486 ± 0.049
4.647IleSer: 4.647 ± 0.073
4.403IleThr: 4.403 ± 0.082
3.991IleVal: 3.991 ± 0.068
0.647IleTrp: 0.647 ± 0.024
2.596IleTyr: 2.596 ± 0.053
0.0IleXaa: 0.0 ± 0.0
Lys
5.305LysAla: 5.305 ± 0.079
0.24LysCys: 0.24 ± 0.013
3.953LysAsp: 3.953 ± 0.063
5.54LysGlu: 5.54 ± 0.079
2.468LysPhe: 2.468 ± 0.044
3.954LysGly: 3.954 ± 0.057
1.349LysHis: 1.349 ± 0.035
4.799LysIle: 4.799 ± 0.079
5.426LysLys: 5.426 ± 0.086
6.293LysLeu: 6.293 ± 0.085
1.69LysMet: 1.69 ± 0.035
4.199LysAsn: 4.199 ± 0.063
2.587LysPro: 2.587 ± 0.048
2.663LysGln: 2.663 ± 0.049
2.965LysArg: 2.965 ± 0.05
3.872LysSer: 3.872 ± 0.064
4.298LysThr: 4.298 ± 0.059
3.893LysVal: 3.893 ± 0.063
0.668LysTrp: 0.668 ± 0.025
2.604LysTyr: 2.604 ± 0.047
0.0LysXaa: 0.0 ± 0.0
Leu
6.834LeuAla: 6.834 ± 0.081
0.665LeuCys: 0.665 ± 0.018
5.714LeuAsp: 5.714 ± 0.077
6.748LeuGlu: 6.748 ± 0.075
4.876LeuPhe: 4.876 ± 0.078
6.332LeuGly: 6.332 ± 0.088
1.579LeuHis: 1.579 ± 0.041
6.731LeuIle: 6.731 ± 0.092
7.598LeuLys: 7.598 ± 0.091
9.076LeuLeu: 9.076 ± 0.126
2.07LeuMet: 2.07 ± 0.044
5.505LeuAsn: 5.505 ± 0.076
3.715LeuPro: 3.715 ± 0.058
3.677LeuGln: 3.677 ± 0.061
3.693LeuArg: 3.693 ± 0.053
6.617LeuSer: 6.617 ± 0.076
5.253LeuThr: 5.253 ± 0.083
5.648LeuVal: 5.648 ± 0.074
0.895LeuTrp: 0.895 ± 0.03
3.344LeuTyr: 3.344 ± 0.058
0.0LeuXaa: 0.0 ± 0.0
Met
1.693MetAla: 1.693 ± 0.046
0.122MetCys: 0.122 ± 0.009
0.971MetAsp: 0.971 ± 0.035
1.244MetGlu: 1.244 ± 0.033
0.767MetPhe: 0.767 ± 0.026
1.417MetGly: 1.417 ± 0.035
0.468MetHis: 0.468 ± 0.021
1.391MetIle: 1.391 ± 0.034
1.729MetLys: 1.729 ± 0.038
2.137MetLeu: 2.137 ± 0.047
0.562MetMet: 0.562 ± 0.024
1.179MetAsn: 1.179 ± 0.032
0.907MetPro: 0.907 ± 0.031
1.004MetGln: 1.004 ± 0.031
1.02MetArg: 1.02 ± 0.03
1.334MetSer: 1.334 ± 0.033
1.138MetThr: 1.138 ± 0.031
1.245MetVal: 1.245 ± 0.032
0.185MetTrp: 0.185 ± 0.013
0.631MetTyr: 0.631 ± 0.025
0.0MetXaa: 0.0 ± 0.0
Asn
4.091AsnAla: 4.091 ± 0.06
0.347AsnCys: 0.347 ± 0.019
2.821AsnAsp: 2.821 ± 0.064
3.343AsnGlu: 3.343 ± 0.056
2.81AsnPhe: 2.81 ± 0.064
3.721AsnGly: 3.721 ± 0.078
0.993AsnHis: 0.993 ± 0.027
3.623AsnIle: 3.623 ± 0.066
3.301AsnLys: 3.301 ± 0.057
5.132AsnLeu: 5.132 ± 0.066
1.154AsnMet: 1.154 ± 0.031
2.847AsnAsn: 2.847 ± 0.066
2.748AsnPro: 2.748 ± 0.055
2.085AsnGln: 2.085 ± 0.045
2.262AsnArg: 2.262 ± 0.05
3.253AsnSer: 3.253 ± 0.061
3.652AsnThr: 3.652 ± 0.064
2.985AsnVal: 2.985 ± 0.048
0.72AsnTrp: 0.72 ± 0.023
2.672AsnTyr: 2.672 ± 0.055
0.0AsnXaa: 0.0 ± 0.0
Pro
2.281ProAla: 2.281 ± 0.045
0.182ProCys: 0.182 ± 0.011
2.408ProAsp: 2.408 ± 0.055
3.517ProGlu: 3.517 ± 0.056
1.928ProPhe: 1.928 ± 0.044
2.272ProGly: 2.272 ± 0.046
0.599ProHis: 0.599 ± 0.021
2.347ProIle: 2.347 ± 0.037
2.447ProLys: 2.447 ± 0.048
3.13ProLeu: 3.13 ± 0.054
0.672ProMet: 0.672 ± 0.024
1.946ProAsn: 1.946 ± 0.042
0.873ProPro: 0.873 ± 0.031
1.592ProGln: 1.592 ± 0.039
1.038ProArg: 1.038 ± 0.03
2.009ProSer: 2.009 ± 0.048
1.854ProThr: 1.854 ± 0.068
2.797ProVal: 2.797 ± 0.053
0.395ProTrp: 0.395 ± 0.021
1.507ProTyr: 1.507 ± 0.041
0.0ProXaa: 0.0 ± 0.0
Gln
2.81GlnAla: 2.81 ± 0.056
0.156GlnCys: 0.156 ± 0.013
2.077GlnAsp: 2.077 ± 0.042
3.098GlnGlu: 3.098 ± 0.052
1.823GlnPhe: 1.823 ± 0.039
2.072GlnGly: 2.072 ± 0.04
0.679GlnHis: 0.679 ± 0.023
2.546GlnIle: 2.546 ± 0.047
2.757GlnLys: 2.757 ± 0.057
4.095GlnLeu: 4.095 ± 0.057
0.873GlnMet: 0.873 ± 0.029
2.296GlnAsn: 2.296 ± 0.044
1.35GlnPro: 1.35 ± 0.031
1.771GlnGln: 1.771 ± 0.049
1.57GlnArg: 1.57 ± 0.036
1.99GlnSer: 1.99 ± 0.039
2.188GlnThr: 2.188 ± 0.042
2.407GlnVal: 2.407 ± 0.046
0.382GlnTrp: 0.382 ± 0.018
1.415GlnTyr: 1.415 ± 0.033
0.0GlnXaa: 0.0 ± 0.0
Arg
2.559ArgAla: 2.559 ± 0.049
0.197ArgCys: 0.197 ± 0.012
2.054ArgAsp: 2.054 ± 0.038
2.527ArgGlu: 2.527 ± 0.046
2.217ArgPhe: 2.217 ± 0.047
2.159ArgGly: 2.159 ± 0.045
0.62ArgHis: 0.62 ± 0.023
3.07ArgIle: 3.07 ± 0.051
2.844ArgLys: 2.844 ± 0.058
3.721ArgLeu: 3.721 ± 0.052
0.912ArgMet: 0.912 ± 0.025
2.281ArgAsn: 2.281 ± 0.043
1.248ArgPro: 1.248 ± 0.031
1.3ArgGln: 1.3 ± 0.036
1.562ArgArg: 1.562 ± 0.037
2.228ArgSer: 2.228 ± 0.044
1.954ArgThr: 1.954 ± 0.038
2.341ArgVal: 2.341 ± 0.044
0.475ArgTrp: 0.475 ± 0.019
1.771ArgTyr: 1.771 ± 0.043
0.0ArgXaa: 0.0 ± 0.0
Ser
4.231SerAla: 4.231 ± 0.061
0.577SerCys: 0.577 ± 0.022
3.246SerAsp: 3.246 ± 0.052
4.121SerGlu: 4.121 ± 0.069
3.572SerPhe: 3.572 ± 0.061
4.703SerGly: 4.703 ± 0.076
0.962SerHis: 0.962 ± 0.03
4.649SerIle: 4.649 ± 0.059
4.172SerLys: 4.172 ± 0.057
6.029SerLeu: 6.029 ± 0.077
1.168SerMet: 1.168 ± 0.031
3.163SerAsn: 3.163 ± 0.05
1.923SerPro: 1.923 ± 0.04
2.069SerGln: 2.069 ± 0.039
2.372SerArg: 2.372 ± 0.04
3.969SerSer: 3.969 ± 0.065
3.501SerThr: 3.501 ± 0.054
4.037SerVal: 4.037 ± 0.07
0.717SerTrp: 0.717 ± 0.027
2.665SerTyr: 2.665 ± 0.056
0.0SerXaa: 0.0 ± 0.0
Thr
4.471ThrAla: 4.471 ± 0.089
0.352ThrCys: 0.352 ± 0.018
3.389ThrAsp: 3.389 ± 0.067
3.747ThrGlu: 3.747 ± 0.058
2.897ThrPhe: 2.897 ± 0.063
4.224ThrGly: 4.224 ± 0.07
1.067ThrHis: 1.067 ± 0.029
4.121ThrIle: 4.121 ± 0.086
3.253ThrLys: 3.253 ± 0.051
5.734ThrLeu: 5.734 ± 0.075
0.975ThrMet: 0.975 ± 0.029
2.82ThrAsn: 2.82 ± 0.048
2.634ThrPro: 2.634 ± 0.051
2.441ThrGln: 2.441 ± 0.046
2.001ThrArg: 2.001 ± 0.042
3.766ThrSer: 3.766 ± 0.061
3.748ThrThr: 3.748 ± 0.092
3.809ThrVal: 3.809 ± 0.097
0.584ThrTrp: 0.584 ± 0.03
2.564ThrTyr: 2.564 ± 0.055
0.0ThrXaa: 0.0 ± 0.0
Val
4.822ValAla: 4.822 ± 0.077
0.49ValCys: 0.49 ± 0.02
3.703ValAsp: 3.703 ± 0.082
3.99ValGlu: 3.99 ± 0.064
3.272ValPhe: 3.272 ± 0.055
3.75ValGly: 3.75 ± 0.06
1.046ValHis: 1.046 ± 0.03
4.401ValIle: 4.401 ± 0.061
3.905ValLys: 3.905 ± 0.069
6.273ValLeu: 6.273 ± 0.091
1.401ValMet: 1.401 ± 0.036
3.317ValAsn: 3.317 ± 0.059
2.222ValPro: 2.222 ± 0.038
2.109ValGln: 2.109 ± 0.043
2.163ValArg: 2.163 ± 0.041
4.254ValSer: 4.254 ± 0.057
3.689ValThr: 3.689 ± 0.081
4.308ValVal: 4.308 ± 0.076
0.626ValTrp: 0.626 ± 0.023
2.522ValTyr: 2.522 ± 0.041
0.0ValXaa: 0.0 ± 0.0
Trp
0.706TrpAla: 0.706 ± 0.024
0.095TrpCys: 0.095 ± 0.009
0.684TrpAsp: 0.684 ± 0.027
0.771TrpGlu: 0.771 ± 0.03
0.577TrpPhe: 0.577 ± 0.025
0.709TrpGly: 0.709 ± 0.028
0.222TrpHis: 0.222 ± 0.015
0.665TrpIle: 0.665 ± 0.026
0.722TrpLys: 0.722 ± 0.027
1.011TrpLeu: 1.011 ± 0.03
0.304TrpMet: 0.304 ± 0.017
0.671TrpAsn: 0.671 ± 0.027
0.307TrpPro: 0.307 ± 0.018
0.482TrpGln: 0.482 ± 0.019
0.461TrpArg: 0.461 ± 0.02
0.683TrpSer: 0.683 ± 0.024
0.527TrpThr: 0.527 ± 0.022
0.681TrpVal: 0.681 ± 0.022
0.181TrpTrp: 0.181 ± 0.012
0.475TrpTyr: 0.475 ± 0.018
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.991TyrAla: 2.991 ± 0.046
0.296TyrCys: 0.296 ± 0.016
2.609TyrAsp: 2.609 ± 0.059
2.564TyrGlu: 2.564 ± 0.045
2.403TyrPhe: 2.403 ± 0.045
2.762TyrGly: 2.762 ± 0.053
0.783TyrHis: 0.783 ± 0.027
2.404TyrIle: 2.404 ± 0.043
2.698TyrLys: 2.698 ± 0.047
3.95TyrLeu: 3.95 ± 0.054
0.742TyrMet: 0.742 ± 0.023
2.337TyrAsn: 2.337 ± 0.053
1.512TyrPro: 1.512 ± 0.035
1.602TyrGln: 1.602 ± 0.042
1.804TyrArg: 1.804 ± 0.04
2.529TyrSer: 2.529 ± 0.049
2.665TyrThr: 2.665 ± 0.061
2.267TyrVal: 2.267 ± 0.048
0.523TyrTrp: 0.523 ± 0.021
1.899TyrTyr: 1.899 ± 0.042
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3687 proteins (1268469 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski