Amino acid dipepetide frequency for Bacteroides graminisolvens DSM 19988 = JCM 15093

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.778AlaAla: 5.778 ± 0.096
0.962AlaCys: 0.962 ± 0.03
4.37AlaAsp: 4.37 ± 0.073
4.511AlaGlu: 4.511 ± 0.077
3.198AlaPhe: 3.198 ± 0.059
5.161AlaGly: 5.161 ± 0.083
1.278AlaHis: 1.278 ± 0.035
4.73AlaIle: 4.73 ± 0.075
4.309AlaLys: 4.309 ± 0.077
6.755AlaLeu: 6.755 ± 0.093
1.921AlaMet: 1.921 ± 0.046
3.446AlaAsn: 3.446 ± 0.059
2.238AlaPro: 2.238 ± 0.05
2.819AlaGln: 2.819 ± 0.055
3.004AlaArg: 3.004 ± 0.057
4.607AlaSer: 4.607 ± 0.072
3.93AlaThr: 3.93 ± 0.068
4.699AlaVal: 4.699 ± 0.08
0.803AlaTrp: 0.803 ± 0.027
2.967AlaTyr: 2.967 ± 0.05
0.0AlaXaa: 0.0 ± 0.0
Cys
0.728CysAla: 0.728 ± 0.026
0.208CysCys: 0.208 ± 0.015
0.647CysAsp: 0.647 ± 0.025
0.645CysGlu: 0.645 ± 0.027
0.631CysPhe: 0.631 ± 0.026
0.963CysGly: 0.963 ± 0.031
0.257CysHis: 0.257 ± 0.015
0.87CysIle: 0.87 ± 0.03
0.721CysLys: 0.721 ± 0.027
1.023CysLeu: 1.023 ± 0.031
0.338CysMet: 0.338 ± 0.017
0.583CysAsn: 0.583 ± 0.025
0.477CysPro: 0.477 ± 0.025
0.323CysGln: 0.323 ± 0.016
0.549CysArg: 0.549 ± 0.024
0.791CysSer: 0.791 ± 0.023
0.599CysThr: 0.599 ± 0.025
0.725CysVal: 0.725 ± 0.029
0.151CysTrp: 0.151 ± 0.011
0.498CysTyr: 0.498 ± 0.025
0.0CysXaa: 0.0 ± 0.0
Asp
4.02AspAla: 4.02 ± 0.06
0.598AspCys: 0.598 ± 0.026
2.639AspAsp: 2.639 ± 0.059
3.744AspGlu: 3.744 ± 0.061
2.974AspPhe: 2.974 ± 0.051
3.945AspGly: 3.945 ± 0.068
0.857AspHis: 0.857 ± 0.034
3.787AspIle: 3.787 ± 0.06
4.066AspLys: 4.066 ± 0.063
4.583AspLeu: 4.583 ± 0.068
1.548AspMet: 1.548 ± 0.04
2.798AspAsn: 2.798 ± 0.054
1.849AspPro: 1.849 ± 0.043
1.369AspGln: 1.369 ± 0.04
2.172AspArg: 2.172 ± 0.048
3.301AspSer: 3.301 ± 0.058
2.568AspThr: 2.568 ± 0.046
3.746AspVal: 3.746 ± 0.061
0.788AspTrp: 0.788 ± 0.025
2.737AspTyr: 2.737 ± 0.059
0.0AspXaa: 0.0 ± 0.0
Glu
4.692GluAla: 4.692 ± 0.085
0.545GluCys: 0.545 ± 0.024
2.998GluAsp: 2.998 ± 0.062
4.815GluGlu: 4.815 ± 0.093
2.603GluPhe: 2.603 ± 0.054
3.908GluGly: 3.908 ± 0.061
1.182GluHis: 1.182 ± 0.032
4.551GluIle: 4.551 ± 0.083
5.07GluLys: 5.07 ± 0.075
6.321GluLeu: 6.321 ± 0.087
2.026GluMet: 2.026 ± 0.045
3.445GluAsn: 3.445 ± 0.061
1.654GluPro: 1.654 ± 0.041
2.44GluGln: 2.44 ± 0.051
2.931GluArg: 2.931 ± 0.055
3.315GluSer: 3.315 ± 0.056
3.235GluThr: 3.235 ± 0.055
4.35GluVal: 4.35 ± 0.071
0.821GluTrp: 0.821 ± 0.029
2.638GluTyr: 2.638 ± 0.055
0.0GluXaa: 0.0 ± 0.0
Phe
3.118PheAla: 3.118 ± 0.054
0.609PheCys: 0.609 ± 0.023
2.734PheAsp: 2.734 ± 0.051
2.541PheGlu: 2.541 ± 0.051
2.208PhePhe: 2.208 ± 0.059
3.255PheGly: 3.255 ± 0.064
0.821PheHis: 0.821 ± 0.027
3.274PheIle: 3.274 ± 0.07
2.623PheLys: 2.623 ± 0.046
4.058PheLeu: 4.058 ± 0.079
1.341PheMet: 1.341 ± 0.036
2.537PheAsn: 2.537 ± 0.053
1.655PhePro: 1.655 ± 0.039
1.387PheGln: 1.387 ± 0.036
2.017PheArg: 2.017 ± 0.043
3.552PheSer: 3.552 ± 0.067
2.737PheThr: 2.737 ± 0.055
2.971PheVal: 2.971 ± 0.049
0.618PheTrp: 0.618 ± 0.026
1.867PheTyr: 1.867 ± 0.044
0.0PheXaa: 0.0 ± 0.0
Gly
4.44GlyAla: 4.44 ± 0.078
0.852GlyCys: 0.852 ± 0.031
3.456GlyAsp: 3.456 ± 0.058
3.859GlyGlu: 3.859 ± 0.07
3.172GlyPhe: 3.172 ± 0.056
4.844GlyGly: 4.844 ± 0.087
1.239GlyHis: 1.239 ± 0.036
5.216GlyIle: 5.216 ± 0.069
5.137GlyLys: 5.137 ± 0.073
5.864GlyLeu: 5.864 ± 0.075
2.063GlyMet: 2.063 ± 0.045
3.627GlyAsn: 3.627 ± 0.07
1.352GlyPro: 1.352 ± 0.036
2.085GlyGln: 2.085 ± 0.04
2.784GlyArg: 2.784 ± 0.058
4.27GlySer: 4.27 ± 0.07
4.213GlyThr: 4.213 ± 0.068
5.037GlyVal: 5.037 ± 0.082
1.013GlyTrp: 1.013 ± 0.033
3.322GlyTyr: 3.322 ± 0.06
0.0GlyXaa: 0.0 ± 0.0
His
1.242HisAla: 1.242 ± 0.036
0.278HisCys: 0.278 ± 0.017
0.871HisAsp: 0.871 ± 0.031
0.999HisGlu: 0.999 ± 0.033
1.03HisPhe: 1.03 ± 0.03
1.176HisGly: 1.176 ± 0.036
0.477HisHis: 0.477 ± 0.021
1.395HisIle: 1.395 ± 0.043
1.122HisLys: 1.122 ± 0.034
1.771HisLeu: 1.771 ± 0.042
0.36HisMet: 0.36 ± 0.016
0.94HisAsn: 0.94 ± 0.033
0.971HisPro: 0.971 ± 0.028
0.629HisGln: 0.629 ± 0.022
0.819HisArg: 0.819 ± 0.03
1.135HisSer: 1.135 ± 0.033
1.032HisThr: 1.032 ± 0.029
1.069HisVal: 1.069 ± 0.031
0.248HisTrp: 0.248 ± 0.016
0.901HisTyr: 0.901 ± 0.029
0.0HisXaa: 0.0 ± 0.0
Ile
5.202IleAla: 5.202 ± 0.064
0.903IleCys: 0.903 ± 0.029
4.314IleAsp: 4.314 ± 0.071
4.474IleGlu: 4.474 ± 0.068
2.676IlePhe: 2.676 ± 0.052
4.593IleGly: 4.593 ± 0.072
1.304IleHis: 1.304 ± 0.034
4.669IleIle: 4.669 ± 0.08
4.517IleLys: 4.517 ± 0.07
5.843IleLeu: 5.843 ± 0.094
1.489IleMet: 1.489 ± 0.044
3.663IleAsn: 3.663 ± 0.066
3.058IlePro: 3.058 ± 0.049
2.254IleGln: 2.254 ± 0.053
3.266IleArg: 3.266 ± 0.058
4.824IleSer: 4.824 ± 0.073
4.193IleThr: 4.193 ± 0.059
4.31IleVal: 4.31 ± 0.068
0.768IleTrp: 0.768 ± 0.028
2.796IleTyr: 2.796 ± 0.06
0.0IleXaa: 0.0 ± 0.0
Lys
4.923LysAla: 4.923 ± 0.078
0.536LysCys: 0.536 ± 0.02
4.008LysAsp: 4.008 ± 0.064
6.04LysGlu: 6.04 ± 0.078
2.183LysPhe: 2.183 ± 0.041
4.853LysGly: 4.853 ± 0.073
1.244LysHis: 1.244 ± 0.036
4.302LysIle: 4.302 ± 0.07
5.294LysLys: 5.294 ± 0.093
5.842LysLeu: 5.842 ± 0.082
2.156LysMet: 2.156 ± 0.042
3.78LysAsn: 3.78 ± 0.064
2.11LysPro: 2.11 ± 0.043
2.725LysGln: 2.725 ± 0.052
3.07LysArg: 3.07 ± 0.061
3.746LysSer: 3.746 ± 0.06
3.662LysThr: 3.662 ± 0.062
4.356LysVal: 4.356 ± 0.073
0.795LysTrp: 0.795 ± 0.025
3.041LysTyr: 3.041 ± 0.05
0.0LysXaa: 0.0 ± 0.0
Leu
6.528LeuAla: 6.528 ± 0.078
1.241LeuCys: 1.241 ± 0.035
4.278LeuAsp: 4.278 ± 0.065
4.871LeuGlu: 4.871 ± 0.074
4.709LeuPhe: 4.709 ± 0.088
5.472LeuGly: 5.472 ± 0.084
1.72LeuHis: 1.72 ± 0.043
5.981LeuIle: 5.981 ± 0.093
6.752LeuLys: 6.752 ± 0.088
9.006LeuLeu: 9.006 ± 0.124
2.468LeuMet: 2.468 ± 0.042
5.153LeuAsn: 5.153 ± 0.08
4.06LeuPro: 4.06 ± 0.062
3.336LeuGln: 3.336 ± 0.07
4.016LeuArg: 4.016 ± 0.063
6.912LeuSer: 6.912 ± 0.092
5.339LeuThr: 5.339 ± 0.074
5.332LeuVal: 5.332 ± 0.076
1.072LeuTrp: 1.072 ± 0.033
3.619LeuTyr: 3.619 ± 0.061
0.0LeuXaa: 0.0 ± 0.0
Met
2.088MetAla: 2.088 ± 0.047
0.263MetCys: 0.263 ± 0.015
1.45MetAsp: 1.45 ± 0.039
1.748MetGlu: 1.748 ± 0.04
1.027MetPhe: 1.027 ± 0.031
1.868MetGly: 1.868 ± 0.04
0.513MetHis: 0.513 ± 0.024
1.682MetIle: 1.682 ± 0.044
2.471MetLys: 2.471 ± 0.039
2.452MetLeu: 2.452 ± 0.052
0.793MetMet: 0.793 ± 0.029
1.675MetAsn: 1.675 ± 0.043
1.158MetPro: 1.158 ± 0.036
1.09MetGln: 1.09 ± 0.032
1.233MetArg: 1.233 ± 0.035
1.577MetSer: 1.577 ± 0.033
1.427MetThr: 1.427 ± 0.036
1.594MetVal: 1.594 ± 0.038
0.297MetTrp: 0.297 ± 0.015
0.878MetTyr: 0.878 ± 0.031
0.0MetXaa: 0.0 ± 0.0
Asn
3.587AsnAla: 3.587 ± 0.062
0.533AsnCys: 0.533 ± 0.022
2.739AsnAsp: 2.739 ± 0.05
3.315AsnGlu: 3.315 ± 0.059
2.331AsnPhe: 2.331 ± 0.052
4.086AsnGly: 4.086 ± 0.068
1.037AsnHis: 1.037 ± 0.031
3.842AsnIle: 3.842 ± 0.07
3.775AsnLys: 3.775 ± 0.062
4.657AsnLeu: 4.657 ± 0.065
1.421AsnMet: 1.421 ± 0.034
2.969AsnAsn: 2.969 ± 0.068
2.496AsnPro: 2.496 ± 0.052
1.854AsnGln: 1.854 ± 0.039
2.375AsnArg: 2.375 ± 0.052
3.214AsnSer: 3.214 ± 0.062
2.831AsnThr: 2.831 ± 0.058
3.28AsnVal: 3.28 ± 0.062
0.711AsnTrp: 0.711 ± 0.028
2.538AsnTyr: 2.538 ± 0.053
0.0AsnXaa: 0.0 ± 0.0
Pro
2.738ProAla: 2.738 ± 0.059
0.348ProCys: 0.348 ± 0.019
2.402ProAsp: 2.402 ± 0.053
2.906ProGlu: 2.906 ± 0.052
1.786ProPhe: 1.786 ± 0.04
2.406ProGly: 2.406 ± 0.053
0.742ProHis: 0.742 ± 0.026
2.304ProIle: 2.304 ± 0.056
1.864ProLys: 1.864 ± 0.037
3.297ProLeu: 3.297 ± 0.056
0.936ProMet: 0.936 ± 0.037
1.653ProAsn: 1.653 ± 0.043
0.758ProPro: 0.758 ± 0.03
1.518ProGln: 1.518 ± 0.04
1.31ProArg: 1.31 ± 0.036
2.272ProSer: 2.272 ± 0.044
1.86ProThr: 1.86 ± 0.045
2.941ProVal: 2.941 ± 0.056
0.451ProTrp: 0.451 ± 0.022
1.653ProTyr: 1.653 ± 0.04
0.0ProXaa: 0.0 ± 0.0
Gln
2.489GlnAla: 2.489 ± 0.047
0.297GlnCys: 0.297 ± 0.016
1.525GlnAsp: 1.525 ± 0.038
2.292GlnGlu: 2.292 ± 0.05
1.363GlnPhe: 1.363 ± 0.036
1.994GlnGly: 1.994 ± 0.04
0.661GlnHis: 0.661 ± 0.027
2.508GlnIle: 2.508 ± 0.049
2.584GlnLys: 2.584 ± 0.052
3.46GlnLeu: 3.46 ± 0.073
1.051GlnMet: 1.051 ± 0.037
1.842GlnAsn: 1.842 ± 0.05
1.183GlnPro: 1.183 ± 0.033
1.636GlnGln: 1.636 ± 0.047
1.612GlnArg: 1.612 ± 0.038
2.071GlnSer: 2.071 ± 0.046
2.112GlnThr: 2.112 ± 0.042
2.275GlnVal: 2.275 ± 0.053
0.498GlnTrp: 0.498 ± 0.021
1.467GlnTyr: 1.467 ± 0.043
0.0GlnXaa: 0.0 ± 0.0
Arg
2.673ArgAla: 2.673 ± 0.05
0.465ArgCys: 0.465 ± 0.022
2.076ArgAsp: 2.076 ± 0.047
2.685ArgGlu: 2.685 ± 0.048
2.21ArgPhe: 2.21 ± 0.046
2.357ArgGly: 2.357 ± 0.049
0.778ArgHis: 0.778 ± 0.028
3.443ArgIle: 3.443 ± 0.052
3.372ArgLys: 3.372 ± 0.058
4.177ArgLeu: 4.177 ± 0.059
1.523ArgMet: 1.523 ± 0.039
2.415ArgAsn: 2.415 ± 0.05
1.479ArgPro: 1.479 ± 0.048
1.563ArgGln: 1.563 ± 0.04
1.921ArgArg: 1.921 ± 0.047
2.414ArgSer: 2.414 ± 0.048
2.315ArgThr: 2.315 ± 0.05
2.681ArgVal: 2.681 ± 0.05
0.627ArgTrp: 0.627 ± 0.025
2.047ArgTyr: 2.047 ± 0.046
0.0ArgXaa: 0.0 ± 0.0
Ser
4.48SerAla: 4.48 ± 0.07
0.836SerCys: 0.836 ± 0.031
3.254SerAsp: 3.254 ± 0.06
3.709SerGlu: 3.709 ± 0.064
3.572SerPhe: 3.572 ± 0.059
4.65SerGly: 4.65 ± 0.07
1.155SerHis: 1.155 ± 0.034
4.629SerIle: 4.629 ± 0.072
3.876SerLys: 3.876 ± 0.056
6.313SerLeu: 6.313 ± 0.085
1.547SerMet: 1.547 ± 0.037
3.075SerAsn: 3.075 ± 0.066
2.295SerPro: 2.295 ± 0.05
2.005SerGln: 2.005 ± 0.043
2.618SerArg: 2.618 ± 0.053
4.385SerSer: 4.385 ± 0.084
3.382SerThr: 3.382 ± 0.064
4.509SerVal: 4.509 ± 0.067
0.862SerTrp: 0.862 ± 0.03
2.938SerTyr: 2.938 ± 0.062
0.0SerXaa: 0.0 ± 0.0
Thr
4.171ThrAla: 4.171 ± 0.069
0.565ThrCys: 0.565 ± 0.027
3.485ThrAsp: 3.485 ± 0.059
3.245ThrGlu: 3.245 ± 0.062
2.598ThrPhe: 2.598 ± 0.048
4.339ThrGly: 4.339 ± 0.07
0.995ThrHis: 0.995 ± 0.03
3.731ThrIle: 3.731 ± 0.059
2.962ThrLys: 2.962 ± 0.057
5.352ThrLeu: 5.352 ± 0.073
1.148ThrMet: 1.148 ± 0.034
2.803ThrAsn: 2.803 ± 0.056
2.618ThrPro: 2.618 ± 0.048
1.744ThrGln: 1.744 ± 0.04
2.164ThrArg: 2.164 ± 0.044
3.466ThrSer: 3.466 ± 0.055
3.167ThrThr: 3.167 ± 0.062
3.945ThrVal: 3.945 ± 0.065
0.648ThrTrp: 0.648 ± 0.027
2.509ThrTyr: 2.509 ± 0.053
0.0ThrXaa: 0.0 ± 0.0
Val
4.753ValAla: 4.753 ± 0.077
0.987ValCys: 0.987 ± 0.031
3.729ValAsp: 3.729 ± 0.059
4.022ValGlu: 4.022 ± 0.066
2.97ValPhe: 2.97 ± 0.055
4.071ValGly: 4.071 ± 0.06
1.102ValHis: 1.102 ± 0.031
4.683ValIle: 4.683 ± 0.071
4.374ValLys: 4.374 ± 0.071
5.974ValLeu: 5.974 ± 0.074
1.67ValMet: 1.67 ± 0.041
3.612ValAsn: 3.612 ± 0.061
2.589ValPro: 2.589 ± 0.052
2.013ValGln: 2.013 ± 0.042
2.779ValArg: 2.779 ± 0.044
4.599ValSer: 4.599 ± 0.063
3.839ValThr: 3.839 ± 0.067
4.737ValVal: 4.737 ± 0.077
0.725ValTrp: 0.725 ± 0.022
2.7ValTyr: 2.7 ± 0.059
0.0ValXaa: 0.0 ± 0.0
Trp
0.84TrpAla: 0.84 ± 0.028
0.171TrpCys: 0.171 ± 0.014
0.698TrpAsp: 0.698 ± 0.027
0.763TrpGlu: 0.763 ± 0.029
0.57TrpPhe: 0.57 ± 0.024
0.96TrpGly: 0.96 ± 0.035
0.248TrpHis: 0.248 ± 0.017
0.797TrpIle: 0.797 ± 0.03
0.912TrpLys: 0.912 ± 0.032
1.154TrpLeu: 1.154 ± 0.032
0.447TrpMet: 0.447 ± 0.021
0.841TrpAsn: 0.841 ± 0.029
0.321TrpPro: 0.321 ± 0.019
0.51TrpGln: 0.51 ± 0.022
0.534TrpArg: 0.534 ± 0.024
0.755TrpSer: 0.755 ± 0.032
0.642TrpThr: 0.642 ± 0.026
0.776TrpVal: 0.776 ± 0.029
0.227TrpTrp: 0.227 ± 0.015
0.519TrpTyr: 0.519 ± 0.023
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.999TyrAla: 2.999 ± 0.054
0.529TyrCys: 0.529 ± 0.022
2.414TyrAsp: 2.414 ± 0.053
2.354TyrGlu: 2.354 ± 0.05
2.113TyrPhe: 2.113 ± 0.053
2.941TyrGly: 2.941 ± 0.066
0.854TyrHis: 0.854 ± 0.03
2.72TyrIle: 2.72 ± 0.051
2.866TyrLys: 2.866 ± 0.056
3.961TyrLeu: 3.961 ± 0.066
1.037TyrMet: 1.037 ± 0.032
2.733TyrAsn: 2.733 ± 0.062
1.824TyrPro: 1.824 ± 0.041
1.625TyrGln: 1.625 ± 0.042
2.049TyrArg: 2.049 ± 0.041
2.883TyrSer: 2.883 ± 0.067
2.575TyrThr: 2.575 ± 0.048
2.596TyrVal: 2.596 ± 0.048
0.563TyrTrp: 0.563 ± 0.025
2.122TyrTyr: 2.122 ± 0.054
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3344 proteins (1078488 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski