Amino acid dipepetide frequency for Desulfotalea psychrophila (strain LSv54 / DSM 12343)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.455AlaAla: 7.455 ± 0.12	1.157AlaCys: 1.157 ± 0.037	4.612AlaAsp: 4.612 ± 0.096	5.932AlaGlu: 5.932 ± 0.1	3.259AlaPhe: 3.259 ± 0.068	7.432AlaGly: 7.432 ± 0.138	1.624AlaHis: 1.624 ± 0.04	6.145AlaIle: 6.145 ± 0.087	4.589AlaLys: 4.589 ± 0.078	9.038AlaLeu: 9.038 ± 0.107	2.383AlaMet: 2.383 ± 0.056	2.874AlaAsn: 2.874 ± 0.066	2.81AlaPro: 2.81 ± 0.061	3.008AlaGln: 3.008 ± 0.069	4.081AlaArg: 4.081 ± 0.075	5.183AlaSer: 5.183 ± 0.084	4.731AlaThr: 4.731 ± 0.089	5.962AlaVal: 5.962 ± 0.109	0.81AlaTrp: 0.81 ± 0.029	2.24AlaTyr: 2.24 ± 0.053	0.0AlaXaa: 0.0 ± 0.0
Cys	1.077CysAla: 1.077 ± 0.037	0.318CysCys: 0.318 ± 0.017	0.619CysAsp: 0.619 ± 0.029	0.655CysGlu: 0.655 ± 0.027	0.635CysPhe: 0.635 ± 0.026	1.262CysGly: 1.262 ± 0.04	0.41CysHis: 0.41 ± 0.026	0.796CysIle: 0.796 ± 0.031	0.591CysLys: 0.591 ± 0.028	1.571CysLeu: 1.571 ± 0.043	0.331CysMet: 0.331 ± 0.018	0.424CysAsn: 0.424 ± 0.024	0.816CysPro: 0.816 ± 0.031	0.556CysGln: 0.556 ± 0.023	0.845CysArg: 0.845 ± 0.031	1.027CysSer: 1.027 ± 0.035	0.678CysThr: 0.678 ± 0.026	0.691CysVal: 0.691 ± 0.026	0.147CysTrp: 0.147 ± 0.012	0.401CysTyr: 0.401 ± 0.02	0.0CysXaa: 0.0 ± 0.0
Asp	3.837AspAla: 3.837 ± 0.072	0.701AspCys: 0.701 ± 0.024	2.507AspAsp: 2.507 ± 0.085	3.117AspGlu: 3.117 ± 0.062	2.536AspPhe: 2.536 ± 0.051	3.837AspGly: 3.837 ± 0.121	1.007AspHis: 1.007 ± 0.047	4.348AspIle: 4.348 ± 0.063	2.788AspLys: 2.788 ± 0.052	5.538AspLeu: 5.538 ± 0.089	1.267AspMet: 1.267 ± 0.042	1.917AspAsn: 1.917 ± 0.065	2.107AspPro: 2.107 ± 0.049	1.607AspGln: 1.607 ± 0.045	2.492AspArg: 2.492 ± 0.056	3.193AspSer: 3.193 ± 0.073	2.338AspThr: 2.338 ± 0.058	3.244AspVal: 3.244 ± 0.084	0.571AspTrp: 0.571 ± 0.026	1.815AspTyr: 1.815 ± 0.044	0.0AspXaa: 0.0 ± 0.0
Glu	5.242GluAla: 5.242 ± 0.075	0.577GluCys: 0.577 ± 0.021	3.067GluAsp: 3.067 ± 0.07	5.118GluGlu: 5.118 ± 0.097	2.174GluPhe: 2.174 ± 0.046	4.1GluGly: 4.1 ± 0.069	1.208GluHis: 1.208 ± 0.038	5.079GluIle: 5.079 ± 0.087	5.088GluLys: 5.088 ± 0.079	6.218GluLeu: 6.218 ± 0.098	1.925GluMet: 1.925 ± 0.051	2.783GluAsn: 2.783 ± 0.054	1.707GluPro: 1.707 ± 0.045	2.821GluGln: 2.821 ± 0.066	3.379GluArg: 3.379 ± 0.065	3.283GluSer: 3.283 ± 0.061	3.154GluThr: 3.154 ± 0.054	4.23GluVal: 4.23 ± 0.073	0.594GluTrp: 0.594 ± 0.027	1.618GluTyr: 1.618 ± 0.05	0.0GluXaa: 0.0 ± 0.0
Phe	3.804PheAla: 3.804 ± 0.057	0.753PheCys: 0.753 ± 0.03	2.165PheAsp: 2.165 ± 0.055	2.053PheGlu: 2.053 ± 0.042	2.547PhePhe: 2.547 ± 0.07	2.955PheGly: 2.955 ± 0.061	0.805PheHis: 0.805 ± 0.031	2.952PheIle: 2.952 ± 0.07	2.027PheLys: 2.027 ± 0.047	4.607PheLeu: 4.607 ± 0.088	1.012PheMet: 1.012 ± 0.033	1.638PheAsn: 1.638 ± 0.04	1.729PhePro: 1.729 ± 0.042	1.333PheGln: 1.333 ± 0.046	1.727PheArg: 1.727 ± 0.047	3.767PheSer: 3.767 ± 0.069	2.462PheThr: 2.462 ± 0.056	2.818PheVal: 2.818 ± 0.063	0.511PheTrp: 0.511 ± 0.024	1.396PheTyr: 1.396 ± 0.042	0.0PheXaa: 0.0 ± 0.0
Gly	6.073GlyAla: 6.073 ± 0.116	1.173GlyCys: 1.173 ± 0.037	3.778GlyAsp: 3.778 ± 0.093	4.637GlyGlu: 4.637 ± 0.075	3.25GlyPhe: 3.25 ± 0.052	5.983GlyGly: 5.983 ± 0.201	1.505GlyHis: 1.505 ± 0.041	5.522GlyIle: 5.522 ± 0.079	4.924GlyLys: 4.924 ± 0.076	7.408GlyLeu: 7.408 ± 0.103	2.166GlyMet: 2.166 ± 0.054	2.733GlyAsn: 2.733 ± 0.114	2.025GlyPro: 2.025 ± 0.046	2.66GlyGln: 2.66 ± 0.059	3.972GlyArg: 3.972 ± 0.08	4.724GlySer: 4.724 ± 0.124	4.056GlyThr: 4.056 ± 0.122	5.241GlyVal: 5.241 ± 0.087	0.86GlyTrp: 0.86 ± 0.032	2.515GlyTyr: 2.515 ± 0.053	0.0GlyXaa: 0.0 ± 0.0
His	1.368HisAla: 1.368 ± 0.04	0.367HisCys: 0.367 ± 0.021	1.002HisAsp: 1.002 ± 0.034	1.022HisGlu: 1.022 ± 0.035	0.951HisPhe: 0.951 ± 0.029	1.535HisGly: 1.535 ± 0.043	0.527HisHis: 0.527 ± 0.023	1.431HisIle: 1.431 ± 0.042	0.958HisLys: 0.958 ± 0.034	2.212HisLeu: 2.212 ± 0.05	0.43HisMet: 0.43 ± 0.019	0.815HisAsn: 0.815 ± 0.032	1.098HisPro: 1.098 ± 0.038	0.746HisGln: 0.746 ± 0.028	1.098HisArg: 1.098 ± 0.033	1.322HisSer: 1.322 ± 0.039	0.886HisThr: 0.886 ± 0.035	1.081HisVal: 1.081 ± 0.035	0.254HisTrp: 0.254 ± 0.015	0.754HisTyr: 0.754 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	6.374IleAla: 6.374 ± 0.086	1.087IleCys: 1.087 ± 0.034	3.968IleAsp: 3.968 ± 0.061	4.685IleGlu: 4.685 ± 0.075	3.283IlePhe: 3.283 ± 0.065	5.097IleGly: 5.097 ± 0.075	1.343IleHis: 1.343 ± 0.039	5.247IleIle: 5.247 ± 0.087	3.773IleLys: 3.773 ± 0.069	6.796IleLeu: 6.796 ± 0.095	1.664IleMet: 1.664 ± 0.048	2.842IleAsn: 2.842 ± 0.067	2.965IlePro: 2.965 ± 0.058	2.027IleGln: 2.027 ± 0.042	3.305IleArg: 3.305 ± 0.063	5.535IleSer: 5.535 ± 0.094	4.019IleThr: 4.019 ± 0.091	4.695IleVal: 4.695 ± 0.065	0.605IleTrp: 0.605 ± 0.025	2.069IleTyr: 2.069 ± 0.049	0.0IleXaa: 0.0 ± 0.0
Lys	4.339LysAla: 4.339 ± 0.07	0.506LysCys: 0.506 ± 0.028	2.799LysAsp: 2.799 ± 0.054	4.317LysGlu: 4.317 ± 0.084	1.823LysPhe: 1.823 ± 0.052	3.686LysGly: 3.686 ± 0.066	1.009LysHis: 1.009 ± 0.031	4.701LysIle: 4.701 ± 0.077	5.109LysLys: 5.109 ± 0.089	4.582LysLeu: 4.582 ± 0.071	1.824LysMet: 1.824 ± 0.045	2.889LysAsn: 2.889 ± 0.059	1.822LysPro: 1.822 ± 0.05	2.051LysGln: 2.051 ± 0.049	3.186LysArg: 3.186 ± 0.066	3.392LysSer: 3.392 ± 0.063	3.269LysThr: 3.269 ± 0.061	3.473LysVal: 3.473 ± 0.062	0.498LysTrp: 0.498 ± 0.025	1.716LysTyr: 1.716 ± 0.046	0.0LysXaa: 0.0 ± 0.0
Leu	10.093LeuAla: 10.093 ± 0.126	1.521LeuCys: 1.521 ± 0.042	5.191LeuAsp: 5.191 ± 0.084	5.894LeuGlu: 5.894 ± 0.1	4.774LeuPhe: 4.774 ± 0.1	7.588LeuGly: 7.588 ± 0.097	2.065LeuHis: 2.065 ± 0.049	6.363LeuIle: 6.363 ± 0.093	5.334LeuLys: 5.334 ± 0.091	11.593LeuLeu: 11.593 ± 0.171	2.334LeuMet: 2.334 ± 0.048	3.496LeuAsn: 3.496 ± 0.066	4.845LeuPro: 4.845 ± 0.073	4.343LeuGln: 4.343 ± 0.081	5.098LeuArg: 5.098 ± 0.075	7.51LeuSer: 7.51 ± 0.108	5.506LeuThr: 5.506 ± 0.1	6.691LeuVal: 6.691 ± 0.099	0.965LeuTrp: 0.965 ± 0.036	2.762LeuTyr: 2.762 ± 0.055	0.0LeuXaa: 0.0 ± 0.0
Met	2.662MetAla: 2.662 ± 0.055	0.255MetCys: 0.255 ± 0.015	1.34MetAsp: 1.34 ± 0.04	1.542MetGlu: 1.542 ± 0.041	0.799MetPhe: 0.799 ± 0.029	2.017MetGly: 2.017 ± 0.045	0.478MetHis: 0.478 ± 0.02	1.579MetIle: 1.579 ± 0.043	1.661MetLys: 1.661 ± 0.045	2.508MetLeu: 2.508 ± 0.051	0.664MetMet: 0.664 ± 0.028	1.018MetAsn: 1.018 ± 0.033	1.163MetPro: 1.163 ± 0.035	0.934MetGln: 0.934 ± 0.029	1.311MetArg: 1.311 ± 0.041	1.787MetSer: 1.787 ± 0.047	1.447MetThr: 1.447 ± 0.038	1.86MetVal: 1.86 ± 0.045	0.199MetTrp: 0.199 ± 0.014	0.491MetTyr: 0.491 ± 0.026	0.0MetXaa: 0.0 ± 0.0
Asn	2.644AsnAla: 2.644 ± 0.077	0.548AsnCys: 0.548 ± 0.023	1.715AsnAsp: 1.715 ± 0.045	1.85AsnGlu: 1.85 ± 0.044	1.708AsnPhe: 1.708 ± 0.042	2.585AsnGly: 2.585 ± 0.063	0.7AsnHis: 0.7 ± 0.028	3.372AsnIle: 3.372 ± 0.072	2.205AsnLys: 2.205 ± 0.072	3.825AsnLeu: 3.825 ± 0.061	1.013AsnMet: 1.013 ± 0.032	1.745AsnAsn: 1.745 ± 0.054	1.845AsnPro: 1.845 ± 0.045	1.314AsnGln: 1.314 ± 0.038	2.119AsnArg: 2.119 ± 0.046	2.618AsnSer: 2.618 ± 0.07	1.834AsnThr: 1.834 ± 0.049	2.305AsnVal: 2.305 ± 0.072	0.436AsnTrp: 0.436 ± 0.021	1.429AsnTyr: 1.429 ± 0.048	0.0AsnXaa: 0.0 ± 0.0
Pro	3.45ProAla: 3.45 ± 0.064	0.518ProCys: 0.518 ± 0.022	1.934ProAsp: 1.934 ± 0.044	3.127ProGlu: 3.127 ± 0.071	1.811ProPhe: 1.811 ± 0.046	2.739ProGly: 2.739 ± 0.06	0.87ProHis: 0.87 ± 0.028	2.544ProIle: 2.544 ± 0.055	1.806ProLys: 1.806 ± 0.048	4.414ProLeu: 4.414 ± 0.074	0.998ProMet: 0.998 ± 0.034	1.217ProAsn: 1.217 ± 0.036	1.467ProPro: 1.467 ± 0.044	1.52ProGln: 1.52 ± 0.044	1.639ProArg: 1.639 ± 0.038	2.28ProSer: 2.28 ± 0.052	2.118ProThr: 2.118 ± 0.051	3.062ProVal: 3.062 ± 0.066	0.461ProTrp: 0.461 ± 0.02	1.24ProTyr: 1.24 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	3.493GlnAla: 3.493 ± 0.071	0.366GlnCys: 0.366 ± 0.02	1.683GlnAsp: 1.683 ± 0.043	2.846GlnGlu: 2.846 ± 0.062	1.281GlnPhe: 1.281 ± 0.035	2.564GlnGly: 2.564 ± 0.055	0.735GlnHis: 0.735 ± 0.025	2.509GlnIle: 2.509 ± 0.047	2.5GlnLys: 2.5 ± 0.06	3.899GlnLeu: 3.899 ± 0.076	0.926GlnMet: 0.926 ± 0.029	1.47GlnAsn: 1.47 ± 0.037	1.239GlnPro: 1.239 ± 0.039	1.77GlnGln: 1.77 ± 0.057	2.028GlnArg: 2.028 ± 0.053	2.058GlnSer: 2.058 ± 0.051	1.908GlnThr: 1.908 ± 0.043	2.551GlnVal: 2.551 ± 0.058	0.373GlnTrp: 0.373 ± 0.019	1.035GlnTyr: 1.035 ± 0.036	0.0GlnXaa: 0.0 ± 0.0
Arg	4.095ArgAla: 4.095 ± 0.07	0.665ArgCys: 0.665 ± 0.026	2.736ArgAsp: 2.736 ± 0.055	3.586ArgGlu: 3.586 ± 0.064	2.123ArgPhe: 2.123 ± 0.052	3.597ArgGly: 3.597 ± 0.066	1.035ArgHis: 1.035 ± 0.032	3.432ArgIle: 3.432 ± 0.067	2.79ArgLys: 2.79 ± 0.069	5.107ArgLeu: 5.107 ± 0.081	1.295ArgMet: 1.295 ± 0.035	1.774ArgAsn: 1.774 ± 0.045	1.893ArgPro: 1.893 ± 0.044	2.24ArgGln: 2.24 ± 0.057	2.903ArgArg: 2.903 ± 0.07	2.934ArgSer: 2.934 ± 0.062	2.136ArgThr: 2.136 ± 0.047	3.503ArgVal: 3.503 ± 0.069	0.527ArgTrp: 0.527 ± 0.023	1.732ArgTyr: 1.732 ± 0.041	0.0ArgXaa: 0.0 ± 0.0
Ser	5.223SerAla: 5.223 ± 0.085	1.104SerCys: 1.104 ± 0.033	2.927SerAsp: 2.927 ± 0.083	3.449SerGlu: 3.449 ± 0.064	3.253SerPhe: 3.253 ± 0.062	5.293SerGly: 5.293 ± 0.119	1.442SerHis: 1.442 ± 0.042	4.536SerIle: 4.536 ± 0.082	3.115SerLys: 3.115 ± 0.054	7.822SerLeu: 7.822 ± 0.116	1.698SerMet: 1.698 ± 0.042	2.173SerAsn: 2.173 ± 0.046	2.897SerPro: 2.897 ± 0.061	2.414SerGln: 2.414 ± 0.054	3.263SerArg: 3.263 ± 0.067	4.878SerSer: 4.878 ± 0.082	3.505SerThr: 3.505 ± 0.085	4.225SerVal: 4.225 ± 0.077	0.828SerTrp: 0.828 ± 0.032	2.231SerTyr: 2.231 ± 0.045	0.0SerXaa: 0.0 ± 0.0
Thr	4.764ThrAla: 4.764 ± 0.099	0.689ThrCys: 0.689 ± 0.025	2.786ThrAsp: 2.786 ± 0.083	3.18ThrGlu: 3.18 ± 0.069	2.109ThrPhe: 2.109 ± 0.044	4.824ThrGly: 4.824 ± 0.112	0.937ThrHis: 0.937 ± 0.026	4.06ThrIle: 4.06 ± 0.083	2.466ThrLys: 2.466 ± 0.054	5.577ThrLeu: 5.577 ± 0.121	1.265ThrMet: 1.265 ± 0.034	1.926ThrAsn: 1.926 ± 0.055	2.475ThrPro: 2.475 ± 0.054	1.373ThrGln: 1.373 ± 0.042	2.183ThrArg: 2.183 ± 0.055	3.365ThrSer: 3.365 ± 0.067	3.18ThrThr: 3.18 ± 0.1	3.857ThrVal: 3.857 ± 0.097	0.514ThrTrp: 0.514 ± 0.028	1.425ThrTyr: 1.425 ± 0.049	0.0ThrXaa: 0.0 ± 0.0
Val	6.288ValAla: 6.288 ± 0.083	0.912ValCys: 0.912 ± 0.032	3.837ValAsp: 3.837 ± 0.074	4.329ValGlu: 4.329 ± 0.077	2.766ValPhe: 2.766 ± 0.053	5.037ValGly: 5.037 ± 0.09	1.257ValHis: 1.257 ± 0.033	4.353ValIle: 4.353 ± 0.066	3.304ValLys: 3.304 ± 0.057	6.701ValLeu: 6.701 ± 0.088	1.593ValMet: 1.593 ± 0.04	2.438ValAsn: 2.438 ± 0.068	2.593ValPro: 2.593 ± 0.061	2.383ValGln: 2.383 ± 0.059	3.063ValArg: 3.063 ± 0.062	4.582ValSer: 4.582 ± 0.09	3.768ValThr: 3.768 ± 0.127	4.977ValVal: 4.977 ± 0.086	0.61ValTrp: 0.61 ± 0.022	1.862ValTyr: 1.862 ± 0.042	0.001ValXaa: 0.001 ± 0.001
Trp	0.812TrpAla: 0.812 ± 0.03	0.148TrpCys: 0.148 ± 0.012	0.477TrpAsp: 0.477 ± 0.021	0.494TrpGlu: 0.494 ± 0.022	0.481TrpPhe: 0.481 ± 0.022	0.703TrpGly: 0.703 ± 0.028	0.225TrpHis: 0.225 ± 0.014	0.566TrpIle: 0.566 ± 0.024	0.513TrpLys: 0.513 ± 0.026	1.252TrpLeu: 1.252 ± 0.043	0.278TrpMet: 0.278 ± 0.019	0.389TrpAsn: 0.389 ± 0.021	0.425TrpPro: 0.425 ± 0.021	0.786TrpGln: 0.786 ± 0.024	0.537TrpArg: 0.537 ± 0.026	0.631TrpSer: 0.631 ± 0.029	0.465TrpThr: 0.465 ± 0.026	0.63TrpVal: 0.63 ± 0.028	0.136TrpTrp: 0.136 ± 0.012	0.271TrpTyr: 0.271 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.231TyrAla: 2.231 ± 0.058	0.488TyrCys: 0.488 ± 0.021	1.622TyrAsp: 1.622 ± 0.041	1.531TyrGlu: 1.531 ± 0.045	1.497TyrPhe: 1.497 ± 0.035	2.374TyrGly: 2.374 ± 0.054	0.673TyrHis: 0.673 ± 0.028	1.84TyrIle: 1.84 ± 0.039	1.451TyrLys: 1.451 ± 0.045	3.299TyrLeu: 3.299 ± 0.063	0.647TyrMet: 0.647 ± 0.026	1.251TyrAsn: 1.251 ± 0.039	1.294TyrPro: 1.294 ± 0.034	1.349TyrGln: 1.349 ± 0.043	1.874TyrArg: 1.874 ± 0.049	2.206TyrSer: 2.206 ± 0.048	1.494TyrThr: 1.494 ± 0.04	1.555TyrVal: 1.555 ± 0.035	0.322TyrTrp: 0.322 ± 0.019	1.061TyrTyr: 1.061 ± 0.036	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.001XaaSer: 0.001 ± 0.001	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3233 proteins (1036698 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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