Amino acid dipepetide frequency for Ulvibacterium marinum

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.174AlaAla: 4.174 ± 0.068	0.573AlaCys: 0.573 ± 0.02	3.414AlaAsp: 3.414 ± 0.055	3.903AlaGlu: 3.903 ± 0.057	3.264AlaPhe: 3.264 ± 0.045	4.088AlaGly: 4.088 ± 0.052	1.289AlaHis: 1.289 ± 0.028	5.09AlaIle: 5.09 ± 0.06	4.351AlaLys: 4.351 ± 0.062	6.833AlaLeu: 6.833 ± 0.081	1.673AlaMet: 1.673 ± 0.032	3.219AlaAsn: 3.219 ± 0.043	2.127AlaPro: 2.127 ± 0.037	2.481AlaGln: 2.481 ± 0.041	2.259AlaArg: 2.259 ± 0.037	4.113AlaSer: 4.113 ± 0.055	3.453AlaThr: 3.453 ± 0.06	3.963AlaVal: 3.963 ± 0.054	0.761AlaTrp: 0.761 ± 0.023	2.552AlaTyr: 2.552 ± 0.036	0.0AlaXaa: 0.0 ± 0.0
Cys	0.474CysAla: 0.474 ± 0.016	0.114CysCys: 0.114 ± 0.008	0.41CysAsp: 0.41 ± 0.017	0.426CysGlu: 0.426 ± 0.017	0.4CysPhe: 0.4 ± 0.015	0.602CysGly: 0.602 ± 0.022	0.228CysHis: 0.228 ± 0.013	0.561CysIle: 0.561 ± 0.016	0.43CysLys: 0.43 ± 0.016	0.681CysLeu: 0.681 ± 0.021	0.157CysMet: 0.157 ± 0.009	0.395CysAsn: 0.395 ± 0.019	0.314CysPro: 0.314 ± 0.016	0.218CysGln: 0.218 ± 0.012	0.237CysArg: 0.237 ± 0.01	0.575CysSer: 0.575 ± 0.02	0.458CysThr: 0.458 ± 0.019	0.402CysVal: 0.402 ± 0.017	0.079CysTrp: 0.079 ± 0.006	0.282CysTyr: 0.282 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	3.691AspAla: 3.691 ± 0.052	0.399AspCys: 0.399 ± 0.015	2.962AspAsp: 2.962 ± 0.051	3.615AspGlu: 3.615 ± 0.05	3.924AspPhe: 3.924 ± 0.048	4.434AspGly: 4.434 ± 0.075	1.069AspHis: 1.069 ± 0.027	4.366AspIle: 4.366 ± 0.06	3.528AspLys: 3.528 ± 0.04	5.321AspLeu: 5.321 ± 0.059	1.276AspMet: 1.276 ± 0.027	2.958AspAsn: 2.958 ± 0.05	2.106AspPro: 2.106 ± 0.042	1.738AspGln: 1.738 ± 0.034	2.257AspArg: 2.257 ± 0.039	3.522AspSer: 3.522 ± 0.053	3.1AspThr: 3.1 ± 0.05	3.547AspVal: 3.547 ± 0.053	0.946AspTrp: 0.946 ± 0.023	2.832AspTyr: 2.832 ± 0.043	0.0AspXaa: 0.0 ± 0.0
Glu	4.255GluAla: 4.255 ± 0.059	0.322GluCys: 0.322 ± 0.015	3.676GluAsp: 3.676 ± 0.049	5.032GluGlu: 5.032 ± 0.066	2.863GluPhe: 2.863 ± 0.042	4.206GluGly: 4.206 ± 0.055	1.287GluHis: 1.287 ± 0.026	5.26GluIle: 5.26 ± 0.052	5.623GluLys: 5.623 ± 0.069	6.306GluLeu: 6.306 ± 0.06	1.747GluMet: 1.747 ± 0.028	4.57GluAsn: 4.57 ± 0.057	1.882GluPro: 1.882 ± 0.036	2.269GluGln: 2.269 ± 0.038	3.013GluArg: 3.013 ± 0.044	3.387GluSer: 3.387 ± 0.044	3.606GluThr: 3.606 ± 0.043	4.416GluVal: 4.416 ± 0.048	0.765GluTrp: 0.765 ± 0.023	2.426GluTyr: 2.426 ± 0.038	0.0GluXaa: 0.0 ± 0.0
Phe	3.014PheAla: 3.014 ± 0.043	0.425PheCys: 0.425 ± 0.016	3.29PheAsp: 3.29 ± 0.052	3.385PheGlu: 3.385 ± 0.044	2.867PhePhe: 2.867 ± 0.053	3.816PheGly: 3.816 ± 0.055	0.933PheHis: 0.933 ± 0.022	3.479PheIle: 3.479 ± 0.04	3.268PheLys: 3.268 ± 0.044	5.129PheLeu: 5.129 ± 0.058	1.187PheMet: 1.187 ± 0.027	2.872PheAsn: 2.872 ± 0.048	1.904PhePro: 1.904 ± 0.033	1.692PheGln: 1.692 ± 0.029	2.022PheArg: 2.022 ± 0.034	3.815PheSer: 3.815 ± 0.048	2.931PheThr: 2.931 ± 0.039	3.144PheVal: 3.144 ± 0.043	0.67PheTrp: 0.67 ± 0.02	2.095PheTyr: 2.095 ± 0.036	0.0PheXaa: 0.0 ± 0.0
Gly	4.317GlyAla: 4.317 ± 0.056	0.653GlyCys: 0.653 ± 0.027	3.807GlyAsp: 3.807 ± 0.061	4.08GlyGlu: 4.08 ± 0.058	3.831GlyPhe: 3.831 ± 0.048	4.822GlyGly: 4.822 ± 0.072	1.423GlyHis: 1.423 ± 0.037	5.777GlyIle: 5.777 ± 0.063	5.181GlyLys: 5.181 ± 0.065	6.616GlyLeu: 6.616 ± 0.06	1.767GlyMet: 1.767 ± 0.035	4.081GlyAsn: 4.081 ± 0.063	1.794GlyPro: 1.794 ± 0.036	2.23GlyGln: 2.23 ± 0.041	2.688GlyArg: 2.688 ± 0.047	4.269GlySer: 4.269 ± 0.06	4.245GlyThr: 4.245 ± 0.066	4.239GlyVal: 4.239 ± 0.048	0.947GlyTrp: 0.947 ± 0.024	3.026GlyTyr: 3.026 ± 0.05	0.0GlyXaa: 0.0 ± 0.0
His	1.084HisAla: 1.084 ± 0.028	0.186HisCys: 0.186 ± 0.011	0.873HisAsp: 0.873 ± 0.024	1.076HisGlu: 1.076 ± 0.026	1.185HisPhe: 1.185 ± 0.027	1.296HisGly: 1.296 ± 0.03	0.536HisHis: 0.536 ± 0.017	1.462HisIle: 1.462 ± 0.029	1.209HisLys: 1.209 ± 0.027	2.043HisLeu: 2.043 ± 0.039	0.445HisMet: 0.445 ± 0.017	0.92HisAsn: 0.92 ± 0.023	1.038HisPro: 1.038 ± 0.027	0.727HisGln: 0.727 ± 0.021	0.819HisArg: 0.819 ± 0.022	1.145HisSer: 1.145 ± 0.023	1.111HisThr: 1.111 ± 0.025	1.064HisVal: 1.064 ± 0.025	0.332HisTrp: 0.332 ± 0.015	0.871HisTyr: 0.871 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	5.313IleAla: 5.313 ± 0.058	0.601IleCys: 0.601 ± 0.02	4.459IleAsp: 4.459 ± 0.056	4.616IleGlu: 4.616 ± 0.062	3.367IlePhe: 3.367 ± 0.054	5.276IleGly: 5.276 ± 0.057	1.443IleHis: 1.443 ± 0.031	4.81IleIle: 4.81 ± 0.061	4.692IleLys: 4.692 ± 0.058	6.971IleLeu: 6.971 ± 0.081	1.368IleMet: 1.368 ± 0.03	3.822IleAsn: 3.822 ± 0.045	3.359IlePro: 3.359 ± 0.055	2.479IleGln: 2.479 ± 0.042	2.954IleArg: 2.954 ± 0.045	5.274IleSer: 5.274 ± 0.065	4.384IleThr: 4.384 ± 0.065	4.461IleVal: 4.461 ± 0.051	0.784IleTrp: 0.784 ± 0.021	2.514IleTyr: 2.514 ± 0.038	0.0IleXaa: 0.0 ± 0.0
Lys	4.519LysAla: 4.519 ± 0.062	0.297LysCys: 0.297 ± 0.014	4.27LysAsp: 4.27 ± 0.047	5.866LysGlu: 5.866 ± 0.068	2.482LysPhe: 2.482 ± 0.037	4.709LysGly: 4.709 ± 0.053	1.259LysHis: 1.259 ± 0.029	5.18LysIle: 5.18 ± 0.065	6.253LysLys: 6.253 ± 0.083	5.85LysLeu: 5.85 ± 0.059	1.816LysMet: 1.816 ± 0.037	4.416LysAsn: 4.416 ± 0.062	2.301LysPro: 2.301 ± 0.038	2.154LysGln: 2.154 ± 0.041	3.123LysArg: 3.123 ± 0.047	4.251LysSer: 4.251 ± 0.056	4.029LysThr: 4.029 ± 0.046	4.445LysVal: 4.445 ± 0.049	0.867LysTrp: 0.867 ± 0.025	2.59LysTyr: 2.59 ± 0.036	0.0LysXaa: 0.0 ± 0.0
Leu	6.356LeuAla: 6.356 ± 0.069	0.695LeuCys: 0.695 ± 0.019	5.602LeuAsp: 5.602 ± 0.063	6.902LeuGlu: 6.902 ± 0.077	5.046LeuPhe: 5.046 ± 0.058	6.756LeuGly: 6.756 ± 0.063	1.689LeuHis: 1.689 ± 0.037	6.333LeuIle: 6.333 ± 0.067	7.19LeuLys: 7.19 ± 0.08	9.314LeuLeu: 9.314 ± 0.098	2.128LeuMet: 2.128 ± 0.043	5.178LeuAsn: 5.178 ± 0.058	3.931LeuPro: 3.931 ± 0.049	3.337LeuGln: 3.337 ± 0.044	3.868LeuArg: 3.868 ± 0.046	6.625LeuSer: 6.625 ± 0.071	5.133LeuThr: 5.133 ± 0.061	5.858LeuVal: 5.858 ± 0.059	1.064LeuTrp: 1.064 ± 0.025	3.277LeuTyr: 3.277 ± 0.047	0.0LeuXaa: 0.0 ± 0.0
Met	1.926MetAla: 1.926 ± 0.038	0.123MetCys: 0.123 ± 0.008	1.538MetAsp: 1.538 ± 0.029	1.759MetGlu: 1.759 ± 0.034	0.849MetPhe: 0.849 ± 0.023	1.873MetGly: 1.873 ± 0.039	0.417MetHis: 0.417 ± 0.016	1.316MetIle: 1.316 ± 0.03	1.906MetLys: 1.906 ± 0.029	1.97MetLeu: 1.97 ± 0.034	0.519MetMet: 0.519 ± 0.019	1.203MetAsn: 1.203 ± 0.028	0.934MetPro: 0.934 ± 0.022	0.821MetGln: 0.821 ± 0.021	0.937MetArg: 0.937 ± 0.024	1.223MetSer: 1.223 ± 0.03	1.172MetThr: 1.172 ± 0.029	1.624MetVal: 1.624 ± 0.035	0.205MetTrp: 0.205 ± 0.012	0.689MetTyr: 0.689 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	3.487AsnAla: 3.487 ± 0.042	0.426AsnCys: 0.426 ± 0.019	2.963AsnAsp: 2.963 ± 0.047	3.339AsnGlu: 3.339 ± 0.046	2.834AsnPhe: 2.834 ± 0.049	4.329AsnGly: 4.329 ± 0.064	1.048AsnHis: 1.048 ± 0.025	3.888AsnIle: 3.888 ± 0.049	3.249AsnLys: 3.249 ± 0.048	5.288AsnLeu: 5.288 ± 0.075	1.177AsnMet: 1.177 ± 0.026	2.836AsnAsn: 2.836 ± 0.058	2.879AsnPro: 2.879 ± 0.047	2.0AsnGln: 2.0 ± 0.032	2.479AsnArg: 2.479 ± 0.038	3.506AsnSer: 3.506 ± 0.051	3.45AsnThr: 3.45 ± 0.053	3.169AsnVal: 3.169 ± 0.049	0.764AsnTrp: 0.764 ± 0.025	2.378AsnTyr: 2.378 ± 0.047	0.0AsnXaa: 0.0 ± 0.0
Pro	1.902ProAla: 1.902 ± 0.035	0.208ProCys: 0.208 ± 0.013	2.493ProAsp: 2.493 ± 0.044	3.172ProGlu: 3.172 ± 0.044	2.075ProPhe: 2.075 ± 0.034	2.399ProGly: 2.399 ± 0.047	0.727ProHis: 0.727 ± 0.023	2.879ProIle: 2.879 ± 0.041	2.789ProLys: 2.789 ± 0.044	3.382ProLeu: 3.382 ± 0.055	0.896ProMet: 0.896 ± 0.021	2.338ProAsn: 2.338 ± 0.041	1.123ProPro: 1.123 ± 0.03	1.186ProGln: 1.186 ± 0.027	1.173ProArg: 1.173 ± 0.025	2.38ProSer: 2.38 ± 0.036	2.036ProThr: 2.036 ± 0.039	2.426ProVal: 2.426 ± 0.037	0.489ProTrp: 0.489 ± 0.018	1.525ProTyr: 1.525 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	1.97GlnAla: 1.97 ± 0.041	0.197GlnCys: 0.197 ± 0.011	1.727GlnAsp: 1.727 ± 0.032	2.465GlnGlu: 2.465 ± 0.035	1.68GlnPhe: 1.68 ± 0.029	2.183GlnGly: 2.183 ± 0.036	0.642GlnHis: 0.642 ± 0.02	2.498GlnIle: 2.498 ± 0.039	2.788GlnLys: 2.788 ± 0.046	3.524GlnLeu: 3.524 ± 0.044	0.894GlnMet: 0.894 ± 0.023	2.095GlnAsn: 2.095 ± 0.035	1.056GlnPro: 1.056 ± 0.023	1.314GlnGln: 1.314 ± 0.03	1.508GlnArg: 1.508 ± 0.027	1.845GlnSer: 1.845 ± 0.034	1.677GlnThr: 1.677 ± 0.03	2.0GlnVal: 2.0 ± 0.031	0.473GlnTrp: 0.473 ± 0.017	1.249GlnTyr: 1.249 ± 0.028	0.0GlnXaa: 0.0 ± 0.0
Arg	2.316ArgAla: 2.316 ± 0.037	0.249ArgCys: 0.249 ± 0.012	2.139ArgAsp: 2.139 ± 0.035	2.616ArgGlu: 2.616 ± 0.046	2.245ArgPhe: 2.245 ± 0.037	2.204ArgGly: 2.204 ± 0.038	0.724ArgHis: 0.724 ± 0.018	3.375ArgIle: 3.375 ± 0.042	3.25ArgLys: 3.25 ± 0.042	3.908ArgLeu: 3.908 ± 0.049	1.034ArgMet: 1.034 ± 0.024	2.459ArgAsn: 2.459 ± 0.042	1.542ArgPro: 1.542 ± 0.033	1.246ArgGln: 1.246 ± 0.029	1.675ArgArg: 1.675 ± 0.033	2.259ArgSer: 2.259 ± 0.034	2.343ArgThr: 2.343 ± 0.038	2.292ArgVal: 2.292 ± 0.037	0.507ArgTrp: 0.507 ± 0.016	1.742ArgTyr: 1.742 ± 0.032	0.0ArgXaa: 0.0 ± 0.0
Ser	3.7SerAla: 3.7 ± 0.046	0.662SerCys: 0.662 ± 0.024	3.531SerAsp: 3.531 ± 0.045	4.102SerGlu: 4.102 ± 0.052	3.725SerPhe: 3.725 ± 0.055	4.849SerGly: 4.849 ± 0.067	1.195SerHis: 1.195 ± 0.027	4.891SerIle: 4.891 ± 0.057	4.426SerLys: 4.426 ± 0.054	6.109SerLeu: 6.109 ± 0.069	1.31SerMet: 1.31 ± 0.029	3.365SerAsn: 3.365 ± 0.056	2.322SerPro: 2.322 ± 0.034	2.055SerGln: 2.055 ± 0.033	2.406SerArg: 2.406 ± 0.037	4.055SerSer: 4.055 ± 0.054	3.386SerThr: 3.386 ± 0.046	3.864SerVal: 3.864 ± 0.052	0.778SerTrp: 0.778 ± 0.021	2.678SerTyr: 2.678 ± 0.037	0.0SerXaa: 0.0 ± 0.0
Thr	3.703ThrAla: 3.703 ± 0.05	0.342ThrCys: 0.342 ± 0.017	3.471ThrAsp: 3.471 ± 0.057	3.454ThrGlu: 3.454 ± 0.049	2.972ThrPhe: 2.972 ± 0.045	4.167ThrGly: 4.167 ± 0.059	1.054ThrHis: 1.054 ± 0.025	4.35ThrIle: 4.35 ± 0.054	3.416ThrLys: 3.416 ± 0.049	5.584ThrLeu: 5.584 ± 0.065	1.125ThrMet: 1.125 ± 0.025	2.775ThrAsn: 2.775 ± 0.051	2.449ThrPro: 2.449 ± 0.045	1.853ThrGln: 1.853 ± 0.033	1.859ThrArg: 1.859 ± 0.032	3.558ThrSer: 3.558 ± 0.057	3.122ThrThr: 3.122 ± 0.057	3.734ThrVal: 3.734 ± 0.064	0.628ThrTrp: 0.628 ± 0.021	2.354ThrTyr: 2.354 ± 0.034	0.0ThrXaa: 0.0 ± 0.0
Val	4.15ValAla: 4.15 ± 0.055	0.526ValCys: 0.526 ± 0.018	3.738ValAsp: 3.738 ± 0.049	3.83ValGlu: 3.83 ± 0.049	3.415ValPhe: 3.415 ± 0.053	3.994ValGly: 3.994 ± 0.052	1.238ValHis: 1.238 ± 0.031	4.207ValIle: 4.207 ± 0.05	3.831ValLys: 3.831 ± 0.054	6.479ValLeu: 6.479 ± 0.069	1.377ValMet: 1.377 ± 0.032	3.133ValAsn: 3.133 ± 0.048	2.533ValPro: 2.533 ± 0.038	2.023ValGln: 2.023 ± 0.037	2.356ValArg: 2.356 ± 0.039	4.407ValSer: 4.407 ± 0.057	3.448ValThr: 3.448 ± 0.052	4.258ValVal: 4.258 ± 0.061	0.729ValTrp: 0.729 ± 0.023	2.266ValTyr: 2.266 ± 0.035	0.0ValXaa: 0.0 ± 0.0
Trp	0.746TrpAla: 0.746 ± 0.021	0.097TrpCys: 0.097 ± 0.007	0.769TrpAsp: 0.769 ± 0.021	0.855TrpGlu: 0.855 ± 0.025	0.632TrpPhe: 0.632 ± 0.021	0.916TrpGly: 0.916 ± 0.028	0.314TrpHis: 0.314 ± 0.015	0.838TrpIle: 0.838 ± 0.02	0.87TrpLys: 0.87 ± 0.023	1.136TrpLeu: 1.136 ± 0.029	0.369TrpMet: 0.369 ± 0.013	0.733TrpAsn: 0.733 ± 0.02	0.376TrpPro: 0.376 ± 0.018	0.483TrpGln: 0.483 ± 0.017	0.537TrpArg: 0.537 ± 0.019	0.726TrpSer: 0.726 ± 0.02	0.634TrpThr: 0.634 ± 0.02	0.766TrpVal: 0.766 ± 0.021	0.213TrpTrp: 0.213 ± 0.012	0.515TrpTyr: 0.515 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.486TyrAla: 2.486 ± 0.042	0.348TyrCys: 0.348 ± 0.015	2.46TyrAsp: 2.46 ± 0.048	2.416TyrGlu: 2.416 ± 0.039	2.281TyrPhe: 2.281 ± 0.034	2.876TyrGly: 2.876 ± 0.047	0.904TyrHis: 0.904 ± 0.024	2.388TyrIle: 2.388 ± 0.036	2.427TyrLys: 2.427 ± 0.044	3.837TyrLeu: 3.837 ± 0.048	0.738TyrMet: 0.738 ± 0.02	2.12TyrAsn: 2.12 ± 0.043	1.63TyrPro: 1.63 ± 0.031	1.477TyrGln: 1.477 ± 0.036	1.957TyrArg: 1.957 ± 0.035	2.476TyrSer: 2.476 ± 0.036	2.254TyrThr: 2.254 ± 0.045	2.263TyrVal: 2.263 ± 0.043	0.524TyrTrp: 0.524 ± 0.018	1.71TyrTyr: 1.71 ± 0.034	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5010 proteins (1768237 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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