Amino acid dipepetide frequency for Saccharomyces cerevisiae virus L-BC (ScV-L-BC) (ScVLa)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.435AlaAla: 5.435 ± 0.154
2.264AlaCys: 2.264 ± 0.304
3.17AlaAsp: 3.17 ± 0.15
4.076AlaGlu: 4.076 ± 0.835
3.623AlaPhe: 3.623 ± 0.343
3.17AlaGly: 3.17 ± 0.15
1.359AlaHis: 1.359 ± 0.039
5.888AlaIle: 5.888 ± 1.366
3.17AlaLys: 3.17 ± 1.589
4.529AlaLeu: 4.529 ± 0.111
6.341AlaMet: 6.341 ± 1.139
4.529AlaAsn: 4.529 ± 0.831
4.076AlaPro: 4.076 ± 0.835
2.717AlaGln: 2.717 ± 0.642
4.982AlaArg: 4.982 ± 0.381
3.623AlaSer: 3.623 ± 0.343
4.529AlaThr: 4.529 ± 0.111
3.17AlaVal: 3.17 ± 0.869
1.812AlaTrp: 1.812 ± 0.188
6.793AlaTyr: 6.793 ± 0.193
0.0AlaXaa: 0.0 ± 0.0
Cys
0.906CysAla: 0.906 ± 0.266
0.0CysCys: 0.0 ± 0.0
0.453CysAsp: 0.453 ± 0.227
0.453CysGlu: 0.453 ± 0.227
0.453CysPhe: 0.453 ± 0.227
1.359CysGly: 1.359 ± 0.039
0.0CysHis: 0.0 ± 0.0
0.906CysIle: 0.906 ± 0.266
0.0CysLys: 0.0 ± 0.0
1.359CysLeu: 1.359 ± 0.039
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.453CysArg: 0.453 ± 0.227
1.812CysSer: 1.812 ± 0.188
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.906CysTrp: 0.906 ± 0.266
1.812CysTyr: 1.812 ± 0.188
0.0CysXaa: 0.0 ± 0.0
Asp
9.511AspAla: 9.511 ± 1.709
0.0AspCys: 0.0 ± 0.0
4.076AspAsp: 4.076 ± 0.604
2.717AspGlu: 2.717 ± 0.077
3.623AspPhe: 3.623 ± 0.377
1.812AspGly: 1.812 ± 0.188
1.812AspHis: 1.812 ± 0.531
5.888AspIle: 5.888 ± 0.072
1.812AspLys: 1.812 ± 0.188
4.076AspLeu: 4.076 ± 0.116
5.435AspMet: 5.435 ± 0.874
4.982AspAsn: 4.982 ± 0.338
2.264AspPro: 2.264 ± 0.304
1.359AspGln: 1.359 ± 0.039
1.359AspArg: 1.359 ± 0.681
2.264AspSer: 2.264 ± 0.304
4.982AspThr: 4.982 ± 0.381
5.888AspVal: 5.888 ± 0.647
0.453AspTrp: 0.453 ± 0.227
1.359AspTyr: 1.359 ± 0.681
0.0AspXaa: 0.0 ± 0.0
Glu
4.529GluAla: 4.529 ± 0.111
0.0GluCys: 0.0 ± 0.0
6.793GluAsp: 6.793 ± 0.912
1.359GluGlu: 1.359 ± 0.039
3.17GluPhe: 3.17 ± 0.57
4.529GluGly: 4.529 ± 0.111
0.453GluHis: 0.453 ± 0.227
4.529GluIle: 4.529 ± 0.111
4.982GluLys: 4.982 ± 1.057
4.076GluLeu: 4.076 ± 0.835
1.812GluMet: 1.812 ± 0.177
0.906GluAsn: 0.906 ± 0.454
1.359GluPro: 1.359 ± 0.758
1.359GluGln: 1.359 ± 0.039
1.359GluArg: 1.359 ± 0.039
3.17GluSer: 3.17 ± 0.15
2.717GluThr: 2.717 ± 0.077
1.812GluVal: 1.812 ± 0.188
0.906GluTrp: 0.906 ± 0.454
1.359GluTyr: 1.359 ± 0.039
0.0GluXaa: 0.0 ± 0.0
Phe
1.812PheAla: 1.812 ± 0.188
0.453PheCys: 0.453 ± 0.227
1.359PheAsp: 1.359 ± 0.039
2.264PheGlu: 2.264 ± 0.304
1.359PhePhe: 1.359 ± 0.681
0.453PheGly: 0.453 ± 0.227
0.453PheHis: 0.453 ± 0.227
2.717PheIle: 2.717 ± 0.077
1.812PheLys: 1.812 ± 0.531
2.717PheLeu: 2.717 ± 0.077
1.812PheMet: 1.812 ± 0.531
3.623PheAsn: 3.623 ± 0.377
2.717PhePro: 2.717 ± 0.077
0.0PheGln: 0.0 ± 0.0
1.812PheArg: 1.812 ± 0.531
4.529PheSer: 4.529 ± 0.111
3.17PheThr: 3.17 ± 0.869
2.717PheVal: 2.717 ± 0.642
0.0PheTrp: 0.0 ± 0.0
3.623PheTyr: 3.623 ± 1.062
0.0PheXaa: 0.0 ± 0.0
Gly
0.906GlyAla: 0.906 ± 0.454
0.453GlyCys: 0.453 ± 0.227
2.717GlyAsp: 2.717 ± 0.642
1.812GlyGlu: 1.812 ± 0.188
1.812GlyPhe: 1.812 ± 0.188
1.812GlyGly: 1.812 ± 0.188
1.359GlyHis: 1.359 ± 0.039
5.435GlyIle: 5.435 ± 0.154
1.812GlyLys: 1.812 ± 0.188
5.888GlyLeu: 5.888 ± 0.072
1.359GlyMet: 1.359 ± 0.039
3.623GlyAsn: 3.623 ± 1.062
0.0GlyPro: 0.0 ± 0.0
3.623GlyGln: 3.623 ± 0.343
7.246GlyArg: 7.246 ± 0.686
4.529GlySer: 4.529 ± 0.608
5.888GlyThr: 5.888 ± 0.792
3.17GlyVal: 3.17 ± 1.589
0.453GlyTrp: 0.453 ± 0.227
1.812GlyTyr: 1.812 ± 0.188
0.0GlyXaa: 0.0 ± 0.0
His
1.812HisAla: 1.812 ± 0.188
1.812HisCys: 1.812 ± 0.188
0.453HisAsp: 0.453 ± 0.227
1.359HisGlu: 1.359 ± 0.039
0.906HisPhe: 0.906 ± 0.266
2.264HisGly: 2.264 ± 0.304
0.906HisHis: 0.906 ± 0.266
0.453HisIle: 0.453 ± 0.227
0.0HisLys: 0.0 ± 0.0
0.0HisLeu: 0.0 ± 0.0
0.0HisMet: 0.0 ± 0.0
0.453HisAsn: 0.453 ± 0.227
0.453HisPro: 0.453 ± 0.227
0.906HisGln: 0.906 ± 0.266
1.359HisArg: 1.359 ± 0.039
2.717HisSer: 2.717 ± 0.642
0.906HisThr: 0.906 ± 0.454
2.264HisVal: 2.264 ± 0.415
0.906HisTrp: 0.906 ± 0.266
0.906HisTyr: 0.906 ± 0.266
0.0HisXaa: 0.0 ± 0.0
Ile
5.888IleAla: 5.888 ± 0.792
0.0IleCys: 0.0 ± 0.0
5.435IleAsp: 5.435 ± 0.154
4.529IleGlu: 4.529 ± 0.608
2.717IlePhe: 2.717 ± 0.077
3.17IleGly: 3.17 ± 0.15
1.359IleHis: 1.359 ± 0.039
1.812IleIle: 1.812 ± 0.531
4.076IleLys: 4.076 ± 0.116
4.529IleLeu: 4.529 ± 0.608
1.812IleMet: 1.812 ± 0.188
4.982IleAsn: 4.982 ± 1.101
1.812IlePro: 1.812 ± 0.531
0.0IleGln: 0.0 ± 0.0
3.623IleArg: 3.623 ± 1.096
4.076IleSer: 4.076 ± 0.604
3.17IleThr: 3.17 ± 0.15
4.982IleVal: 4.982 ± 0.338
0.0IleTrp: 0.0 ± 0.0
0.906IleTyr: 0.906 ± 0.266
0.0IleXaa: 0.0 ± 0.0
Lys
3.623LysAla: 3.623 ± 0.377
0.0LysCys: 0.0 ± 0.0
5.435LysAsp: 5.435 ± 0.874
2.264LysGlu: 2.264 ± 1.135
2.264LysPhe: 2.264 ± 0.304
3.17LysGly: 3.17 ± 0.869
0.0LysHis: 0.0 ± 0.0
1.812LysIle: 1.812 ± 0.188
2.264LysLys: 2.264 ± 0.415
4.076LysLeu: 4.076 ± 0.604
1.359LysMet: 1.359 ± 0.039
1.359LysAsn: 1.359 ± 0.681
3.17LysPro: 3.17 ± 0.57
1.812LysGln: 1.812 ± 0.188
1.812LysArg: 1.812 ± 0.188
2.717LysSer: 2.717 ± 0.077
3.623LysThr: 3.623 ± 1.096
2.717LysVal: 2.717 ± 0.077
2.717LysTrp: 2.717 ± 0.642
4.982LysTyr: 4.982 ± 0.338
0.0LysXaa: 0.0 ± 0.0
Leu
4.529LeuAla: 4.529 ± 0.831
0.0LeuCys: 0.0 ± 0.0
5.435LeuAsp: 5.435 ± 0.874
3.623LeuGlu: 3.623 ± 0.377
6.341LeuPhe: 6.341 ± 0.299
2.264LeuGly: 2.264 ± 0.304
1.359LeuHis: 1.359 ± 0.039
2.264LeuIle: 2.264 ± 1.135
2.717LeuLys: 2.717 ± 0.642
5.435LeuLeu: 5.435 ± 0.874
0.906LeuMet: 0.906 ± 0.266
5.888LeuAsn: 5.888 ± 0.072
4.982LeuPro: 4.982 ± 1.101
2.717LeuGln: 2.717 ± 0.077
5.888LeuArg: 5.888 ± 0.072
5.435LeuSer: 5.435 ± 1.593
7.246LeuThr: 7.246 ± 0.034
7.699LeuVal: 7.699 ± 0.459
0.906LeuTrp: 0.906 ± 0.266
4.982LeuTyr: 4.982 ± 0.381
0.0LeuXaa: 0.0 ± 0.0
Met
1.812MetAla: 1.812 ± 0.188
0.0MetCys: 0.0 ± 0.0
2.264MetAsp: 2.264 ± 0.304
0.453MetGlu: 0.453 ± 0.227
0.906MetPhe: 0.906 ± 0.266
2.264MetGly: 2.264 ± 0.304
0.0MetHis: 0.0 ± 0.0
2.717MetIle: 2.717 ± 0.077
0.906MetLys: 0.906 ± 0.454
4.076MetLeu: 4.076 ± 0.835
1.359MetMet: 1.359 ± 0.039
2.264MetAsn: 2.264 ± 0.304
3.17MetPro: 3.17 ± 0.57
1.359MetGln: 1.359 ± 0.039
2.717MetArg: 2.717 ± 0.077
3.623MetSer: 3.623 ± 0.343
1.812MetThr: 1.812 ± 0.531
2.264MetVal: 2.264 ± 0.415
0.0MetTrp: 0.0 ± 0.0
0.906MetTyr: 0.906 ± 0.266
0.0MetXaa: 0.0 ± 0.0
Asn
5.888AsnAla: 5.888 ± 0.647
0.453AsnCys: 0.453 ± 0.227
1.812AsnAsp: 1.812 ± 0.531
0.453AsnGlu: 0.453 ± 0.227
1.812AsnPhe: 1.812 ± 0.188
5.435AsnGly: 5.435 ± 0.154
0.906AsnHis: 0.906 ± 0.266
2.717AsnIle: 2.717 ± 0.642
1.812AsnLys: 1.812 ± 0.531
4.529AsnLeu: 4.529 ± 0.111
3.17AsnMet: 3.17 ± 0.57
0.906AsnAsn: 0.906 ± 0.454
1.812AsnPro: 1.812 ± 0.531
1.812AsnGln: 1.812 ± 0.188
3.17AsnArg: 3.17 ± 0.15
4.529AsnSer: 4.529 ± 0.111
3.17AsnThr: 3.17 ± 0.15
5.435AsnVal: 5.435 ± 0.565
0.906AsnTrp: 0.906 ± 0.266
4.076AsnTyr: 4.076 ± 0.604
0.0AsnXaa: 0.0 ± 0.0
Pro
4.076ProAla: 4.076 ± 0.835
0.0ProCys: 0.0 ± 0.0
1.812ProAsp: 1.812 ± 0.531
3.17ProGlu: 3.17 ± 0.57
2.264ProPhe: 2.264 ± 0.304
1.812ProGly: 1.812 ± 0.188
0.0ProHis: 0.0 ± 0.0
3.623ProIle: 3.623 ± 1.782
1.812ProLys: 1.812 ± 0.531
3.17ProLeu: 3.17 ± 0.15
0.453ProMet: 0.453 ± 0.227
2.264ProAsn: 2.264 ± 0.304
1.359ProPro: 1.359 ± 0.758
1.812ProGln: 1.812 ± 0.531
1.359ProArg: 1.359 ± 0.039
2.717ProSer: 2.717 ± 0.797
3.17ProThr: 3.17 ± 0.15
4.076ProVal: 4.076 ± 0.835
0.0ProTrp: 0.0 ± 0.0
2.264ProTyr: 2.264 ± 0.304
0.0ProXaa: 0.0 ± 0.0
Gln
2.717GlnAla: 2.717 ± 0.077
0.453GlnCys: 0.453 ± 0.227
0.906GlnAsp: 0.906 ± 0.454
2.717GlnGlu: 2.717 ± 0.077
0.0GlnPhe: 0.0 ± 0.0
2.717GlnGly: 2.717 ± 0.077
0.906GlnHis: 0.906 ± 0.454
0.906GlnIle: 0.906 ± 0.266
0.453GlnLys: 0.453 ± 0.227
4.076GlnLeu: 4.076 ± 0.835
0.0GlnMet: 0.0 ± 0.0
0.453GlnAsn: 0.453 ± 0.227
0.453GlnPro: 0.453 ± 0.227
1.812GlnGln: 1.812 ± 0.908
0.453GlnArg: 0.453 ± 0.227
0.453GlnSer: 0.453 ± 0.227
1.812GlnThr: 1.812 ± 0.531
2.264GlnVal: 2.264 ± 0.304
0.453GlnTrp: 0.453 ± 0.227
4.076GlnTyr: 4.076 ± 0.116
0.0GlnXaa: 0.0 ± 0.0
Arg
7.699ArgAla: 7.699 ± 0.98
0.0ArgCys: 0.0 ± 0.0
4.076ArgAsp: 4.076 ± 0.116
3.17ArgGlu: 3.17 ± 0.869
1.359ArgPhe: 1.359 ± 0.039
3.17ArgGly: 3.17 ± 0.869
0.906ArgHis: 0.906 ± 0.454
3.623ArgIle: 3.623 ± 1.096
5.888ArgLys: 5.888 ± 0.072
4.982ArgLeu: 4.982 ± 0.381
2.717ArgMet: 2.717 ± 0.642
4.076ArgAsn: 4.076 ± 0.116
2.717ArgPro: 2.717 ± 0.077
1.359ArgGln: 1.359 ± 0.039
1.812ArgArg: 1.812 ± 0.188
1.359ArgSer: 1.359 ± 0.681
4.982ArgThr: 4.982 ± 0.381
5.435ArgVal: 5.435 ± 0.154
0.0ArgTrp: 0.0 ± 0.0
1.359ArgTyr: 1.359 ± 0.039
0.0ArgXaa: 0.0 ± 0.0
Ser
2.717SerAla: 2.717 ± 0.077
3.623SerCys: 3.623 ± 0.343
4.076SerAsp: 4.076 ± 0.116
3.623SerGlu: 3.623 ± 0.343
0.0SerPhe: 0.0 ± 0.0
5.435SerGly: 5.435 ± 0.154
0.453SerHis: 0.453 ± 0.227
4.529SerIle: 4.529 ± 0.608
3.623SerLys: 3.623 ± 0.377
10.417SerLeu: 10.417 ± 1.255
0.0SerMet: 0.0 ± 0.0
3.17SerAsn: 3.17 ± 0.57
1.812SerPro: 1.812 ± 0.531
1.359SerGln: 1.359 ± 0.681
5.888SerArg: 5.888 ± 0.647
6.341SerSer: 6.341 ± 1.139
2.717SerThr: 2.717 ± 0.642
4.982SerVal: 4.982 ± 0.338
0.0SerTrp: 0.0 ± 0.0
2.717SerTyr: 2.717 ± 0.642
0.0SerXaa: 0.0 ± 0.0
Thr
4.982ThrAla: 4.982 ± 0.381
0.906ThrCys: 0.906 ± 0.266
4.529ThrAsp: 4.529 ± 0.608
3.623ThrGlu: 3.623 ± 1.062
2.717ThrPhe: 2.717 ± 0.642
5.888ThrGly: 5.888 ± 0.072
4.076ThrHis: 4.076 ± 0.604
3.17ThrIle: 3.17 ± 0.15
2.264ThrLys: 2.264 ± 1.135
5.435ThrLeu: 5.435 ± 0.874
3.17ThrMet: 3.17 ± 0.171
4.076ThrAsn: 4.076 ± 0.116
0.453ThrPro: 0.453 ± 0.227
0.906ThrGln: 0.906 ± 0.454
6.793ThrArg: 6.793 ± 1.246
2.717ThrSer: 2.717 ± 0.642
2.717ThrThr: 2.717 ± 0.642
4.529ThrVal: 4.529 ± 0.111
0.906ThrTrp: 0.906 ± 0.266
3.17ThrTyr: 3.17 ± 0.15
0.0ThrXaa: 0.0 ± 0.0
Val
6.793ValAla: 6.793 ± 0.912
0.0ValCys: 0.0 ± 0.0
8.152ValAsp: 8.152 ± 0.488
4.982ValGlu: 4.982 ± 0.338
1.812ValPhe: 1.812 ± 0.188
1.359ValGly: 1.359 ± 0.681
0.453ValHis: 0.453 ± 0.227
3.17ValIle: 3.17 ± 0.15
7.246ValLys: 7.246 ± 0.034
3.623ValLeu: 3.623 ± 1.815
1.812ValMet: 1.812 ± 0.188
3.623ValAsn: 3.623 ± 0.343
4.982ValPro: 4.982 ± 0.381
2.717ValGln: 2.717 ± 0.797
4.529ValArg: 4.529 ± 1.55
8.152ValSer: 8.152 ± 0.951
3.17ValThr: 3.17 ± 0.15
2.717ValVal: 2.717 ± 0.077
0.0ValTrp: 0.0 ± 0.0
0.453ValTyr: 0.453 ± 0.227
0.0ValXaa: 0.0 ± 0.0
Trp
0.906TrpAla: 0.906 ± 0.266
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.453TrpGlu: 0.453 ± 0.227
0.906TrpPhe: 0.906 ± 0.266
1.359TrpGly: 1.359 ± 0.039
0.906TrpHis: 0.906 ± 0.266
1.359TrpIle: 1.359 ± 0.681
1.359TrpLys: 1.359 ± 0.039
0.906TrpLeu: 0.906 ± 0.454
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.453TrpGln: 0.453 ± 0.227
0.906TrpArg: 0.906 ± 0.454
0.0TrpSer: 0.0 ± 0.0
0.453TrpThr: 0.453 ± 0.227
1.812TrpVal: 1.812 ± 0.531
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.717TyrAla: 2.717 ± 0.077
0.453TyrCys: 0.453 ± 0.227
2.717TyrAsp: 2.717 ± 0.642
4.529TyrGlu: 4.529 ± 0.608
1.359TyrPhe: 1.359 ± 0.039
2.264TyrGly: 2.264 ± 0.304
3.17TyrHis: 3.17 ± 0.15
1.359TyrIle: 1.359 ± 0.039
3.17TyrLys: 3.17 ± 0.15
2.717TyrLeu: 2.717 ± 0.642
0.906TyrMet: 0.906 ± 0.266
3.623TyrAsn: 3.623 ± 0.377
3.623TyrPro: 3.623 ± 1.062
0.0TyrGln: 0.0 ± 0.0
3.17TyrArg: 3.17 ± 0.869
2.717TyrSer: 2.717 ± 0.077
6.793TyrThr: 6.793 ± 0.912
1.812TyrVal: 1.812 ± 0.188
0.453TyrTrp: 0.453 ± 0.227
3.17TyrTyr: 3.17 ± 0.57
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2209 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski