Amino acid dipepetide frequency for Alces alces faeces associated microvirus MP15 5067

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.183AlaAla: 2.183 ± 1.886
0.728AlaCys: 0.728 ± 0.742
6.55AlaAsp: 6.55 ± 2.666
4.367AlaGlu: 4.367 ± 2.225
2.183AlaPhe: 2.183 ± 1.35
3.639AlaGly: 3.639 ± 2.398
1.456AlaHis: 1.456 ± 1.148
2.911AlaIle: 2.911 ± 1.2
2.183AlaLys: 2.183 ± 2.484
4.367AlaLeu: 4.367 ± 2.969
0.728AlaMet: 0.728 ± 0.629
5.822AlaAsn: 5.822 ± 2.801
1.456AlaPro: 1.456 ± 0.587
5.095AlaGln: 5.095 ± 3.021
5.095AlaArg: 5.095 ± 1.357
5.095AlaSer: 5.095 ± 2.261
2.911AlaThr: 2.911 ± 1.732
2.911AlaVal: 2.911 ± 1.078
0.728AlaTrp: 0.728 ± 0.629
3.639AlaTyr: 3.639 ± 1.374
0.0AlaXaa: 0.0 ± 0.0
Cys
1.456CysAla: 1.456 ± 0.879
1.456CysCys: 1.456 ± 1.148
1.456CysAsp: 1.456 ± 1.148
0.728CysGlu: 0.728 ± 0.742
1.456CysPhe: 1.456 ± 0.611
1.456CysGly: 1.456 ± 1.484
0.0CysHis: 0.0 ± 0.0
0.728CysIle: 0.728 ± 0.742
0.728CysLys: 0.728 ± 0.742
2.183CysLeu: 2.183 ± 1.282
0.728CysMet: 0.728 ± 0.742
0.0CysAsn: 0.0 ± 0.0
0.728CysPro: 0.728 ± 0.45
0.0CysGln: 0.0 ± 0.0
0.728CysArg: 0.728 ± 0.742
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.639AspAla: 3.639 ± 1.214
0.728AspCys: 0.728 ± 0.742
4.367AspAsp: 4.367 ± 1.217
5.095AspGlu: 5.095 ± 0.66
5.095AspPhe: 5.095 ± 1.906
3.639AspGly: 3.639 ± 1.507
0.728AspHis: 0.728 ± 0.45
1.456AspIle: 1.456 ± 0.9
1.456AspLys: 1.456 ± 0.879
10.917AspLeu: 10.917 ± 3.648
1.456AspMet: 1.456 ± 1.257
5.095AspAsn: 5.095 ± 1.906
4.367AspPro: 4.367 ± 1.328
0.728AspGln: 0.728 ± 0.629
2.911AspArg: 2.911 ± 1.11
3.639AspSer: 3.639 ± 1.745
5.822AspThr: 5.822 ± 1.71
6.55AspVal: 6.55 ± 1.915
0.0AspTrp: 0.0 ± 0.0
6.55AspTyr: 6.55 ± 1.635
0.0AspXaa: 0.0 ± 0.0
Glu
7.278GluAla: 7.278 ± 2.319
0.0GluCys: 0.0 ± 0.0
5.095GluAsp: 5.095 ± 1.949
1.456GluGlu: 1.456 ± 0.587
4.367GluPhe: 4.367 ± 3.443
0.728GluGly: 0.728 ± 0.45
2.911GluHis: 2.911 ± 1.049
2.183GluIle: 2.183 ± 1.13
2.911GluLys: 2.911 ± 1.894
4.367GluLeu: 4.367 ± 2.225
0.728GluMet: 0.728 ± 0.742
5.095GluAsn: 5.095 ± 4.211
2.183GluPro: 2.183 ± 0.585
2.911GluGln: 2.911 ± 3.703
5.095GluArg: 5.095 ± 1.357
4.367GluSer: 4.367 ± 2.048
3.639GluThr: 3.639 ± 1.219
6.55GluVal: 6.55 ± 1.702
1.456GluTrp: 1.456 ± 0.879
4.367GluTyr: 4.367 ± 1.796
0.0GluXaa: 0.0 ± 0.0
Phe
4.367PheAla: 4.367 ± 1.166
1.456PheCys: 1.456 ± 0.611
3.639PheAsp: 3.639 ± 2.326
0.728PheGlu: 0.728 ± 0.45
2.911PhePhe: 2.911 ± 1.11
3.639PheGly: 3.639 ± 0.835
1.456PheHis: 1.456 ± 0.9
1.456PheIle: 1.456 ± 0.611
2.911PheLys: 2.911 ± 1.221
0.728PheLeu: 0.728 ± 0.45
0.728PheMet: 0.728 ± 0.819
2.911PheAsn: 2.911 ± 0.563
2.183PhePro: 2.183 ± 0.775
5.822PheGln: 5.822 ± 1.378
2.911PheArg: 2.911 ± 1.8
2.911PheSer: 2.911 ± 1.8
0.728PheThr: 0.728 ± 0.45
4.367PheVal: 4.367 ± 1.217
0.0PheTrp: 0.0 ± 0.0
4.367PheTyr: 4.367 ± 1.832
0.0PheXaa: 0.0 ± 0.0
Gly
2.183GlyAla: 2.183 ± 1.886
1.456GlyCys: 1.456 ± 1.338
3.639GlyAsp: 3.639 ± 1.745
5.095GlyGlu: 5.095 ± 0.66
2.183GlyPhe: 2.183 ± 1.35
2.183GlyGly: 2.183 ± 1.35
0.728GlyHis: 0.728 ± 0.45
3.639GlyIle: 3.639 ± 1.507
4.367GlyLys: 4.367 ± 2.564
5.095GlyLeu: 5.095 ± 1.056
2.183GlyMet: 2.183 ± 0.775
2.911GlyAsn: 2.911 ± 1.11
0.0GlyPro: 0.0 ± 0.0
1.456GlyGln: 1.456 ± 0.611
0.728GlyArg: 0.728 ± 0.45
5.095GlySer: 5.095 ± 1.861
2.911GlyThr: 2.911 ± 1.078
5.095GlyVal: 5.095 ± 1.257
0.0GlyTrp: 0.0 ± 0.0
4.367GlyTyr: 4.367 ± 0.975
0.0GlyXaa: 0.0 ± 0.0
His
0.728HisAla: 0.728 ± 0.742
0.728HisCys: 0.728 ± 0.45
1.456HisAsp: 1.456 ± 0.9
1.456HisGlu: 1.456 ± 0.879
2.183HisPhe: 2.183 ± 1.35
0.728HisGly: 0.728 ± 0.742
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.728HisLys: 0.728 ± 0.742
0.728HisLeu: 0.728 ± 0.742
1.456HisMet: 1.456 ± 1.108
2.183HisAsn: 2.183 ± 1.35
0.728HisPro: 0.728 ± 0.45
2.183HisGln: 2.183 ± 1.35
2.183HisArg: 2.183 ± 1.13
0.0HisSer: 0.0 ± 0.0
1.456HisThr: 1.456 ± 0.587
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
1.456HisTyr: 1.456 ± 1.338
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
0.0IleCys: 0.0 ± 0.0
3.639IleAsp: 3.639 ± 1.219
2.911IleGlu: 2.911 ± 1.2
2.911IlePhe: 2.911 ± 1.11
4.367IleGly: 4.367 ± 1.217
1.456IleHis: 1.456 ± 0.611
1.456IleIle: 1.456 ± 0.611
3.639IleLys: 3.639 ± 1.017
2.183IleLeu: 2.183 ± 0.837
1.456IleMet: 1.456 ± 1.148
0.728IleAsn: 0.728 ± 0.45
2.911IlePro: 2.911 ± 1.221
1.456IleGln: 1.456 ± 0.587
0.728IleArg: 0.728 ± 0.45
2.183IleSer: 2.183 ± 0.837
2.911IleThr: 2.911 ± 0.563
0.728IleVal: 0.728 ± 1.246
0.0IleTrp: 0.0 ± 0.0
1.456IleTyr: 1.456 ± 0.9
0.0IleXaa: 0.0 ± 0.0
Lys
3.639LysAla: 3.639 ± 1.894
0.728LysCys: 0.728 ± 0.742
5.095LysAsp: 5.095 ± 2.679
4.367LysGlu: 4.367 ± 2.234
0.728LysPhe: 0.728 ± 0.742
2.911LysGly: 2.911 ± 1.8
0.0LysHis: 0.0 ± 0.0
1.456LysIle: 1.456 ± 1.338
6.55LysLys: 6.55 ± 3.983
5.095LysLeu: 5.095 ± 2.292
1.456LysMet: 1.456 ± 0.804
2.183LysAsn: 2.183 ± 1.886
2.183LysPro: 2.183 ± 0.775
1.456LysGln: 1.456 ± 2.491
5.095LysArg: 5.095 ± 3.311
4.367LysSer: 4.367 ± 2.734
2.911LysThr: 2.911 ± 0.563
2.911LysVal: 2.911 ± 1.221
0.0LysTrp: 0.0 ± 0.0
4.367LysTyr: 4.367 ± 1.017
0.0LysXaa: 0.0 ± 0.0
Leu
2.911LeuAla: 2.911 ± 2.514
0.728LeuCys: 0.728 ± 0.45
6.55LeuAsp: 6.55 ± 0.13
5.095LeuGlu: 5.095 ± 1.949
1.456LeuPhe: 1.456 ± 0.611
2.911LeuGly: 2.911 ± 1.461
1.456LeuHis: 1.456 ± 0.587
2.911LeuIle: 2.911 ± 1.11
6.55LeuLys: 6.55 ± 1.702
2.911LeuLeu: 2.911 ± 1.208
1.456LeuMet: 1.456 ± 0.611
4.367LeuAsn: 4.367 ± 0.975
5.822LeuPro: 5.822 ± 1.486
2.911LeuGln: 2.911 ± 1.61
5.095LeuArg: 5.095 ± 2.088
6.55LeuSer: 6.55 ± 1.351
2.183LeuThr: 2.183 ± 1.769
7.278LeuVal: 7.278 ± 1.318
1.456LeuTrp: 1.456 ± 0.9
5.822LeuTyr: 5.822 ± 1.747
0.0LeuXaa: 0.0 ± 0.0
Met
2.183MetAla: 2.183 ± 1.644
0.0MetCys: 0.0 ± 0.0
2.183MetAsp: 2.183 ± 1.35
0.0MetGlu: 0.0 ± 0.0
1.456MetPhe: 1.456 ± 0.587
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
1.456MetIle: 1.456 ± 1.148
0.0MetLys: 0.0 ± 0.0
2.911MetLeu: 2.911 ± 1.2
0.728MetMet: 0.728 ± 0.742
0.728MetAsn: 0.728 ± 0.742
1.456MetPro: 1.456 ± 0.587
4.367MetGln: 4.367 ± 1.456
2.911MetArg: 2.911 ± 1.461
2.911MetSer: 2.911 ± 1.2
1.456MetThr: 1.456 ± 0.587
1.456MetVal: 1.456 ± 0.9
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
4.367AsnAla: 4.367 ± 1.762
0.728AsnCys: 0.728 ± 0.629
2.911AsnAsp: 2.911 ± 1.221
2.911AsnGlu: 2.911 ± 1.732
0.728AsnPhe: 0.728 ± 0.629
4.367AsnGly: 4.367 ± 2.634
0.0AsnHis: 0.0 ± 0.0
3.639AsnIle: 3.639 ± 1.423
2.911AsnLys: 2.911 ± 1.758
5.822AsnLeu: 5.822 ± 1.5
0.728AsnMet: 0.728 ± 0.742
4.367AsnAsn: 4.367 ± 1.169
1.456AsnPro: 1.456 ± 0.879
0.728AsnGln: 0.728 ± 0.45
2.911AsnArg: 2.911 ± 0.563
4.367AsnSer: 4.367 ± 0.641
4.367AsnThr: 4.367 ± 1.927
5.822AsnVal: 5.822 ± 1.23
0.728AsnTrp: 0.728 ± 0.742
2.183AsnTyr: 2.183 ± 0.837
0.0AsnXaa: 0.0 ± 0.0
Pro
1.456ProAla: 1.456 ± 0.611
1.456ProCys: 1.456 ± 1.484
1.456ProAsp: 1.456 ± 0.587
2.911ProGlu: 2.911 ± 1.11
5.095ProPhe: 5.095 ± 2.358
0.728ProGly: 0.728 ± 0.45
0.728ProHis: 0.728 ± 0.742
2.911ProIle: 2.911 ± 1.11
0.0ProLys: 0.0 ± 0.0
2.911ProLeu: 2.911 ± 2.254
0.728ProMet: 0.728 ± 0.45
0.728ProAsn: 0.728 ± 0.742
0.0ProPro: 0.0 ± 0.0
2.183ProGln: 2.183 ± 0.775
1.456ProArg: 1.456 ± 0.611
2.911ProSer: 2.911 ± 1.8
4.367ProThr: 4.367 ± 0.975
2.911ProVal: 2.911 ± 1.049
0.0ProTrp: 0.0 ± 0.0
4.367ProTyr: 4.367 ± 1.796
0.0ProXaa: 0.0 ± 0.0
Gln
5.822GlnAla: 5.822 ± 4.225
0.0GlnCys: 0.0 ± 0.0
0.728GlnAsp: 0.728 ± 0.629
2.911GlnGlu: 2.911 ± 3.703
2.911GlnPhe: 2.911 ± 1.049
2.183GlnGly: 2.183 ± 1.35
0.728GlnHis: 0.728 ± 0.45
0.728GlnIle: 0.728 ± 0.629
3.639GlnLys: 3.639 ± 2.551
3.639GlnLeu: 3.639 ± 1.276
2.183GlnMet: 2.183 ± 1.042
3.639GlnAsn: 3.639 ± 1.863
2.911GlnPro: 2.911 ± 0.563
1.456GlnGln: 1.456 ± 0.879
3.639GlnArg: 3.639 ± 1.243
2.911GlnSer: 2.911 ± 0.563
2.911GlnThr: 2.911 ± 1.208
2.911GlnVal: 2.911 ± 1.721
0.0GlnTrp: 0.0 ± 0.0
1.456GlnTyr: 1.456 ± 0.611
0.0GlnXaa: 0.0 ± 0.0
Arg
6.55ArgAla: 6.55 ± 2.277
1.456ArgCys: 1.456 ± 0.611
2.183ArgAsp: 2.183 ± 0.775
6.55ArgGlu: 6.55 ± 3.55
2.183ArgPhe: 2.183 ± 1.35
2.183ArgGly: 2.183 ± 1.084
0.0ArgHis: 0.0 ± 0.0
2.183ArgIle: 2.183 ± 0.837
3.639ArgLys: 3.639 ± 3.477
5.095ArgLeu: 5.095 ± 1.218
1.456ArgMet: 1.456 ± 1.148
1.456ArgAsn: 1.456 ± 0.587
1.456ArgPro: 1.456 ± 0.611
0.728ArgGln: 0.728 ± 0.629
4.367ArgArg: 4.367 ± 1.676
2.183ArgSer: 2.183 ± 0.837
6.55ArgThr: 6.55 ± 3.367
2.911ArgVal: 2.911 ± 1.208
0.0ArgTrp: 0.0 ± 0.0
3.639ArgTyr: 3.639 ± 2.736
0.0ArgXaa: 0.0 ± 0.0
Ser
5.095SerAla: 5.095 ± 3.021
1.456SerCys: 1.456 ± 1.484
6.55SerAsp: 6.55 ± 3.236
10.189SerGlu: 10.189 ± 2.162
1.456SerPhe: 1.456 ± 0.611
2.911SerGly: 2.911 ± 1.208
1.456SerHis: 1.456 ± 0.9
4.367SerIle: 4.367 ± 2.701
3.639SerLys: 3.639 ± 0.684
5.095SerLeu: 5.095 ± 1.257
2.911SerMet: 2.911 ± 1.049
5.095SerAsn: 5.095 ± 1.572
1.456SerPro: 1.456 ± 0.611
2.911SerGln: 2.911 ± 1.61
2.911SerArg: 2.911 ± 1.208
7.278SerSer: 7.278 ± 4.501
2.183SerThr: 2.183 ± 1.13
1.456SerVal: 1.456 ± 1.148
0.728SerTrp: 0.728 ± 0.629
2.183SerTyr: 2.183 ± 0.775
0.0SerXaa: 0.0 ± 0.0
Thr
6.55ThrAla: 6.55 ± 2.84
0.0ThrCys: 0.0 ± 0.0
2.911ThrAsp: 2.911 ± 1.11
0.728ThrGlu: 0.728 ± 1.246
3.639ThrPhe: 3.639 ± 0.835
5.095ThrGly: 5.095 ± 2.029
1.456ThrHis: 1.456 ± 0.611
1.456ThrIle: 1.456 ± 1.148
3.639ThrLys: 3.639 ± 0.835
4.367ThrLeu: 4.367 ± 0.975
2.911ThrMet: 2.911 ± 0.563
2.911ThrAsn: 2.911 ± 1.208
3.639ThrPro: 3.639 ± 1.507
2.183ThrGln: 2.183 ± 1.116
4.367ThrArg: 4.367 ± 1.673
2.911ThrSer: 2.911 ± 1.175
3.639ThrThr: 3.639 ± 1.745
2.911ThrVal: 2.911 ± 1.175
0.0ThrTrp: 0.0 ± 0.0
2.911ThrTyr: 2.911 ± 0.983
0.0ThrXaa: 0.0 ± 0.0
Val
3.639ValAla: 3.639 ± 1.688
0.0ValCys: 0.0 ± 0.0
5.822ValAsp: 5.822 ± 5.835
5.822ValGlu: 5.822 ± 3.153
4.367ValPhe: 4.367 ± 0.934
8.006ValGly: 8.006 ± 2.553
3.639ValHis: 3.639 ± 1.688
0.728ValIle: 0.728 ± 0.45
3.639ValLys: 3.639 ± 1.866
2.911ValLeu: 2.911 ± 0.563
0.728ValMet: 0.728 ± 0.629
0.0ValAsn: 0.0 ± 0.0
2.183ValPro: 2.183 ± 1.282
4.367ValGln: 4.367 ± 1.017
1.456ValArg: 1.456 ± 0.587
5.822ValSer: 5.822 ± 2.12
3.639ValThr: 3.639 ± 1.32
2.183ValVal: 2.183 ± 0.837
0.728ValTrp: 0.728 ± 0.629
2.911ValTyr: 2.911 ± 1.11
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.728TrpAsp: 0.728 ± 0.45
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.728TrpHis: 0.728 ± 0.45
0.728TrpIle: 0.728 ± 0.629
0.728TrpLys: 0.728 ± 0.629
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.728TrpAsn: 0.728 ± 0.629
0.728TrpPro: 0.728 ± 0.742
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
1.456TrpSer: 1.456 ± 0.611
0.728TrpThr: 0.728 ± 0.629
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.728TrpTyr: 0.728 ± 0.742
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
0.728TyrCys: 0.728 ± 0.742
7.278TyrAsp: 7.278 ± 2.169
4.367TyrGlu: 4.367 ± 1.676
3.639TyrPhe: 3.639 ± 1.32
3.639TyrGly: 3.639 ± 1.907
1.456TyrHis: 1.456 ± 1.484
0.728TyrIle: 0.728 ± 0.45
3.639TyrLys: 3.639 ± 1.866
5.095TyrLeu: 5.095 ± 2.088
0.728TyrMet: 0.728 ± 0.45
5.095TyrAsn: 5.095 ± 1.635
1.456TyrPro: 1.456 ± 1.148
4.367TyrGln: 4.367 ± 1.303
2.183TyrArg: 2.183 ± 1.22
4.367TyrSer: 4.367 ± 1.832
2.911TyrThr: 2.911 ± 1.208
3.639TyrVal: 3.639 ± 1.243
1.456TyrTrp: 1.456 ± 0.611
1.456TyrTyr: 1.456 ± 1.148
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1375 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski