Amino acid dipepetide frequency for Sesamum indicum (Oriental sesame) (Sesamum orientale)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.05AlaAla: 7.05 ± 0.041	1.269AlaCys: 1.269 ± 0.012	3.416AlaAsp: 3.416 ± 0.017	4.599AlaGlu: 4.599 ± 0.025	2.763AlaPhe: 2.763 ± 0.017	4.399AlaGly: 4.399 ± 0.025	1.375AlaHis: 1.375 ± 0.012	3.809AlaIle: 3.809 ± 0.019	4.022AlaLys: 4.022 ± 0.022	6.773AlaLeu: 6.773 ± 0.033	1.791AlaMet: 1.791 ± 0.012	2.658AlaAsn: 2.658 ± 0.017	3.009AlaPro: 3.009 ± 0.02	2.282AlaGln: 2.282 ± 0.017	3.61AlaArg: 3.61 ± 0.02	6.155AlaSer: 6.155 ± 0.029	3.593AlaThr: 3.593 ± 0.019	5.089AlaVal: 5.089 ± 0.024	0.78AlaTrp: 0.78 ± 0.009	1.863AlaTyr: 1.863 ± 0.013	0.005AlaXaa: 0.005 ± 0.001
Cys	1.014CysAla: 1.014 ± 0.01	0.501CysCys: 0.501 ± 0.008	0.849CysAsp: 0.849 ± 0.009	0.895CysGlu: 0.895 ± 0.01	0.84CysPhe: 0.84 ± 0.008	1.379CysGly: 1.379 ± 0.014	0.46CysHis: 0.46 ± 0.007	0.988CysIle: 0.988 ± 0.009	1.094CysLys: 1.094 ± 0.013	1.793CysLeu: 1.793 ± 0.014	0.435CysMet: 0.435 ± 0.006	0.817CysAsn: 0.817 ± 0.009	0.926CysPro: 0.926 ± 0.012	0.597CysGln: 0.597 ± 0.009	1.107CysArg: 1.107 ± 0.012	1.788CysSer: 1.788 ± 0.015	0.85CysThr: 0.85 ± 0.009	1.022CysVal: 1.022 ± 0.011	0.226CysTrp: 0.226 ± 0.004	0.539CysTyr: 0.539 ± 0.007	0.001CysXaa: 0.001 ± 0.0
Asp	3.678AspAla: 3.678 ± 0.02	0.936AspCys: 0.936 ± 0.01	3.634AspAsp: 3.634 ± 0.026	4.15AspGlu: 4.15 ± 0.024	2.358AspPhe: 2.358 ± 0.016	3.828AspGly: 3.828 ± 0.02	1.286AspHis: 1.286 ± 0.011	3.036AspIle: 3.036 ± 0.02	2.769AspLys: 2.769 ± 0.017	4.977AspLeu: 4.977 ± 0.022	1.334AspMet: 1.334 ± 0.012	2.086AspAsn: 2.086 ± 0.014	2.707AspPro: 2.707 ± 0.014	1.782AspGln: 1.782 ± 0.012	2.511AspArg: 2.511 ± 0.018	4.282AspSer: 4.282 ± 0.021	2.184AspThr: 2.184 ± 0.015	3.688AspVal: 3.688 ± 0.018	0.704AspTrp: 0.704 ± 0.009	1.575AspTyr: 1.575 ± 0.013	0.002AspXaa: 0.002 ± 0.0
Glu	4.908GluAla: 4.908 ± 0.026	0.904GluCys: 0.904 ± 0.01	3.971GluAsp: 3.971 ± 0.025	6.163GluGlu: 6.163 ± 0.043	2.391GluPhe: 2.391 ± 0.016	3.705GluGly: 3.705 ± 0.02	1.273GluHis: 1.273 ± 0.012	3.754GluIle: 3.754 ± 0.023	4.896GluLys: 4.896 ± 0.032	6.041GluLeu: 6.041 ± 0.025	1.81GluMet: 1.81 ± 0.015	3.271GluAsn: 3.271 ± 0.025	2.19GluPro: 2.19 ± 0.015	2.235GluGln: 2.235 ± 0.014	3.508GluArg: 3.508 ± 0.022	4.646GluSer: 4.646 ± 0.024	3.096GluThr: 3.096 ± 0.02	4.201GluVal: 4.201 ± 0.021	0.777GluTrp: 0.777 ± 0.01	1.707GluTyr: 1.707 ± 0.014	0.002GluXaa: 0.002 ± 0.001
Phe	2.577PheAla: 2.577 ± 0.017	0.852PheCys: 0.852 ± 0.008	2.287PheAsp: 2.287 ± 0.014	2.2PheGlu: 2.2 ± 0.016	1.872PhePhe: 1.872 ± 0.017	2.977PheGly: 2.977 ± 0.019	1.093PheHis: 1.093 ± 0.01	1.972PheIle: 1.972 ± 0.016	1.977PheLys: 1.977 ± 0.013	4.28PheLeu: 4.28 ± 0.023	0.953PheMet: 0.953 ± 0.01	1.652PheAsn: 1.652 ± 0.014	2.099PhePro: 2.099 ± 0.016	1.553PheGln: 1.553 ± 0.013	2.117PheArg: 2.117 ± 0.014	4.028PheSer: 4.028 ± 0.022	2.002PheThr: 2.002 ± 0.015	2.643PheVal: 2.643 ± 0.017	0.542PheTrp: 0.542 ± 0.007	1.259PheTyr: 1.259 ± 0.012	0.001PheXaa: 0.001 ± 0.0
Gly	4.066GlyAla: 4.066 ± 0.021	1.259GlyCys: 1.259 ± 0.012	3.404GlyAsp: 3.404 ± 0.019	3.751GlyGlu: 3.751 ± 0.02	3.085GlyPhe: 3.085 ± 0.02	5.534GlyGly: 5.534 ± 0.041	1.528GlyHis: 1.528 ± 0.014	3.582GlyIle: 3.582 ± 0.021	4.094GlyLys: 4.094 ± 0.021	5.94GlyLeu: 5.94 ± 0.028	1.493GlyMet: 1.493 ± 0.014	3.115GlyAsn: 3.115 ± 0.021	2.632GlyPro: 2.632 ± 0.017	2.096GlyGln: 2.096 ± 0.016	3.755GlyArg: 3.755 ± 0.023	6.041GlySer: 6.041 ± 0.028	3.223GlyThr: 3.223 ± 0.022	4.258GlyVal: 4.258 ± 0.021	0.917GlyTrp: 0.917 ± 0.01	2.093GlyTyr: 2.093 ± 0.015	0.005GlyXaa: 0.005 ± 0.001
His	1.48HisAla: 1.48 ± 0.012	0.514HisCys: 0.514 ± 0.006	1.189HisAsp: 1.189 ± 0.013	1.314HisGlu: 1.314 ± 0.011	1.057HisPhe: 1.057 ± 0.01	1.712HisGly: 1.712 ± 0.013	0.988HisHis: 0.988 ± 0.012	1.213HisIle: 1.213 ± 0.012	1.194HisLys: 1.194 ± 0.011	2.386HisLeu: 2.386 ± 0.017	0.572HisMet: 0.572 ± 0.008	0.958HisAsn: 0.958 ± 0.011	1.389HisPro: 1.389 ± 0.011	1.049HisGln: 1.049 ± 0.01	1.374HisArg: 1.374 ± 0.012	1.955HisSer: 1.955 ± 0.013	0.959HisThr: 0.959 ± 0.01	1.513HisVal: 1.513 ± 0.014	0.308HisTrp: 0.308 ± 0.006	0.706HisTyr: 0.706 ± 0.009	0.001HisXaa: 0.001 ± 0.0
Ile	3.61IleAla: 3.61 ± 0.018	1.091IleCys: 1.091 ± 0.011	2.884IleAsp: 2.884 ± 0.017	3.116IleGlu: 3.116 ± 0.02	2.215IlePhe: 2.215 ± 0.015	3.294IleGly: 3.294 ± 0.02	1.312IleHis: 1.312 ± 0.011	2.721IleIle: 2.721 ± 0.019	2.846IleLys: 2.846 ± 0.016	5.251IleLeu: 5.251 ± 0.027	1.161IleMet: 1.161 ± 0.011	2.157IleAsn: 2.157 ± 0.016	2.934IlePro: 2.934 ± 0.021	1.986IleGln: 1.986 ± 0.015	2.683IleArg: 2.683 ± 0.016	4.884IleSer: 4.884 ± 0.025	2.557IleThr: 2.557 ± 0.015	3.384IleVal: 3.384 ± 0.021	0.692IleTrp: 0.692 ± 0.009	1.5IleTyr: 1.5 ± 0.013	0.002IleXaa: 0.002 ± 0.0
Lys	4.066LysAla: 4.066 ± 0.022	0.947LysCys: 0.947 ± 0.009	3.283LysAsp: 3.283 ± 0.019	4.562LysGlu: 4.562 ± 0.03	2.178LysPhe: 2.178 ± 0.014	3.519LysGly: 3.519 ± 0.02	1.345LysHis: 1.345 ± 0.011	3.152LysIle: 3.152 ± 0.018	4.608LysLys: 4.608 ± 0.031	5.95LysLeu: 5.95 ± 0.026	1.508LysMet: 1.508 ± 0.013	2.716LysAsn: 2.716 ± 0.018	2.751LysPro: 2.751 ± 0.017	2.315LysGln: 2.315 ± 0.017	3.624LysArg: 3.624 ± 0.022	4.657LysSer: 4.657 ± 0.028	2.805LysThr: 2.805 ± 0.018	3.764LysVal: 3.764 ± 0.023	0.804LysTrp: 0.804 ± 0.009	1.693LysTyr: 1.693 ± 0.013	0.002LysXaa: 0.002 ± 0.0
Leu	6.657LeuAla: 6.657 ± 0.031	1.773LeuCys: 1.773 ± 0.015	5.056LeuAsp: 5.056 ± 0.023	6.356LeuGlu: 6.356 ± 0.032	3.736LeuPhe: 3.736 ± 0.02	5.782LeuGly: 5.782 ± 0.028	2.566LeuHis: 2.566 ± 0.017	4.621LeuIle: 4.621 ± 0.028	6.079LeuLys: 6.079 ± 0.026	9.803LeuLeu: 9.803 ± 0.047	2.162LeuMet: 2.162 ± 0.014	3.84LeuAsn: 3.84 ± 0.02	5.231LeuPro: 5.231 ± 0.024	4.339LeuGln: 4.339 ± 0.022	5.51LeuArg: 5.51 ± 0.025	8.492LeuSer: 8.492 ± 0.039	4.287LeuThr: 4.287 ± 0.022	6.249LeuVal: 6.249 ± 0.031	1.121LeuTrp: 1.121 ± 0.013	2.533LeuTyr: 2.533 ± 0.019	0.004LeuXaa: 0.004 ± 0.001
Met	2.161MetAla: 2.161 ± 0.012	0.322MetCys: 0.322 ± 0.006	1.439MetAsp: 1.439 ± 0.011	1.979MetGlu: 1.979 ± 0.013	0.794MetPhe: 0.794 ± 0.008	1.653MetGly: 1.653 ± 0.013	0.547MetHis: 0.547 ± 0.007	1.186MetIle: 1.186 ± 0.01	1.61MetLys: 1.61 ± 0.013	2.191MetLeu: 2.191 ± 0.014	0.687MetMet: 0.687 ± 0.009	1.016MetAsn: 1.016 ± 0.011	1.057MetPro: 1.057 ± 0.011	0.963MetGln: 0.963 ± 0.011	1.233MetArg: 1.233 ± 0.01	1.761MetSer: 1.761 ± 0.011	1.029MetThr: 1.029 ± 0.008	1.626MetVal: 1.626 ± 0.014	0.268MetTrp: 0.268 ± 0.006	0.59MetTyr: 0.59 ± 0.008	0.001MetXaa: 0.001 ± 0.0
Asn	2.778AsnAla: 2.778 ± 0.017	0.847AsnCys: 0.847 ± 0.01	2.095AsnAsp: 2.095 ± 0.015	2.524AsnGlu: 2.524 ± 0.017	1.887AsnPhe: 1.887 ± 0.015	3.233AsnGly: 3.233 ± 0.021	1.076AsnHis: 1.076 ± 0.011	2.382AsnIle: 2.382 ± 0.015	2.32AsnLys: 2.32 ± 0.014	4.446AsnLeu: 4.446 ± 0.024	1.095AsnMet: 1.095 ± 0.01	2.063AsnAsn: 2.063 ± 0.019	2.372AsnPro: 2.372 ± 0.017	1.689AsnGln: 1.689 ± 0.013	2.08AsnArg: 2.08 ± 0.013	3.991AsnSer: 3.991 ± 0.022	1.892AsnThr: 1.892 ± 0.012	2.787AsnVal: 2.787 ± 0.016	0.564AsnTrp: 0.564 ± 0.008	1.345AsnTyr: 1.345 ± 0.012	0.002AsnXaa: 0.002 ± 0.0
Pro	3.257ProAla: 3.257 ± 0.019	0.762ProCys: 0.762 ± 0.009	2.635ProAsp: 2.635 ± 0.017	3.233ProGlu: 3.233 ± 0.02	2.019ProPhe: 2.019 ± 0.014	2.947ProGly: 2.947 ± 0.022	1.154ProHis: 1.154 ± 0.011	2.297ProIle: 2.297 ± 0.016	2.719ProLys: 2.719 ± 0.019	4.424ProLeu: 4.424 ± 0.02	0.995ProMet: 0.995 ± 0.011	2.242ProAsn: 2.242 ± 0.015	4.227ProPro: 4.227 ± 0.064	1.894ProGln: 1.894 ± 0.017	2.523ProArg: 2.523 ± 0.018	5.081ProSer: 5.081 ± 0.027	2.698ProThr: 2.698 ± 0.018	3.241ProVal: 3.241 ± 0.016	0.622ProTrp: 0.622 ± 0.009	1.341ProTyr: 1.341 ± 0.013	0.003ProXaa: 0.003 ± 0.0
Gln	2.453GlnAla: 2.453 ± 0.019	0.573GlnCys: 0.573 ± 0.009	1.733GlnAsp: 1.733 ± 0.014	2.597GlnGlu: 2.597 ± 0.017	1.368GlnPhe: 1.368 ± 0.011	2.096GlnGly: 2.096 ± 0.015	0.931GlnHis: 0.931 ± 0.009	2.003GlnIle: 2.003 ± 0.014	2.428GlnLys: 2.428 ± 0.017	3.699GlnLeu: 3.699 ± 0.019	0.998GlnMet: 0.998 ± 0.01	1.797GlnAsn: 1.797 ± 0.014	1.82GlnPro: 1.82 ± 0.016	2.071GlnGln: 2.071 ± 0.027	2.168GlnArg: 2.168 ± 0.014	2.833GlnSer: 2.833 ± 0.016	1.741GlnThr: 1.741 ± 0.013	2.355GlnVal: 2.355 ± 0.015	0.459GlnTrp: 0.459 ± 0.006	0.975GlnTyr: 0.975 ± 0.011	0.002GlnXaa: 0.002 ± 0.0
Arg	3.546ArgAla: 3.546 ± 0.02	0.951ArgCys: 0.951 ± 0.01	2.75ArgAsp: 2.75 ± 0.019	3.439ArgGlu: 3.439 ± 0.022	2.183ArgPhe: 2.183 ± 0.015	3.324ArgGly: 3.324 ± 0.019	1.319ArgHis: 1.319 ± 0.011	2.973ArgIle: 2.973 ± 0.018	3.959ArgLys: 3.959 ± 0.021	5.104ArgLeu: 5.104 ± 0.024	1.353ArgMet: 1.353 ± 0.012	2.546ArgAsn: 2.546 ± 0.016	2.507ArgPro: 2.507 ± 0.017	1.946ArgGln: 1.946 ± 0.014	4.199ArgArg: 4.199 ± 0.031	4.475ArgSer: 4.475 ± 0.027	2.565ArgThr: 2.565 ± 0.016	3.363ArgVal: 3.363 ± 0.016	0.756ArgTrp: 0.756 ± 0.008	1.478ArgTyr: 1.478 ± 0.012	0.003ArgXaa: 0.003 ± 0.001
Ser	5.799SerAla: 5.799 ± 0.026	1.723SerCys: 1.723 ± 0.015	4.511SerAsp: 4.511 ± 0.024	4.891SerGlu: 4.891 ± 0.024	3.79SerPhe: 3.79 ± 0.022	6.15SerGly: 6.15 ± 0.028	1.99SerHis: 1.99 ± 0.013	4.432SerIle: 4.432 ± 0.022	4.793SerLys: 4.793 ± 0.025	8.34SerLeu: 8.34 ± 0.033	2.047SerMet: 2.047 ± 0.014	3.915SerAsn: 3.915 ± 0.021	4.737SerPro: 4.737 ± 0.035	3.022SerGln: 3.022 ± 0.021	4.74SerArg: 4.74 ± 0.026	10.895SerSer: 10.895 ± 0.055	4.713SerThr: 4.713 ± 0.023	5.265SerVal: 5.265 ± 0.025	1.173SerTrp: 1.173 ± 0.012	2.294SerTyr: 2.294 ± 0.016	0.003SerXaa: 0.003 ± 0.001
Thr	3.558ThrAla: 3.558 ± 0.02	0.905ThrCys: 0.905 ± 0.01	2.304ThrAsp: 2.304 ± 0.014	2.812ThrGlu: 2.812 ± 0.018	1.967ThrPhe: 1.967 ± 0.013	3.302ThrGly: 3.302 ± 0.018	1.02ThrHis: 1.02 ± 0.011	2.644ThrIle: 2.644 ± 0.015	2.529ThrLys: 2.529 ± 0.015	4.558ThrLeu: 4.558 ± 0.023	1.115ThrMet: 1.115 ± 0.01	2.012ThrAsn: 2.012 ± 0.012	2.679ThrPro: 2.679 ± 0.019	1.479ThrGln: 1.479 ± 0.012	2.438ThrArg: 2.438 ± 0.016	4.6ThrSer: 4.6 ± 0.026	2.827ThrThr: 2.827 ± 0.019	3.324ThrVal: 3.324 ± 0.018	0.624ThrTrp: 0.624 ± 0.008	1.368ThrTyr: 1.368 ± 0.011	0.002ThrXaa: 0.002 ± 0.0
Val	4.959ValAla: 4.959 ± 0.024	1.139ValCys: 1.139 ± 0.012	3.794ValAsp: 3.794 ± 0.02	4.499ValGlu: 4.499 ± 0.021	2.631ValPhe: 2.631 ± 0.017	4.183ValGly: 4.183 ± 0.022	1.53ValHis: 1.53 ± 0.013	3.36ValIle: 3.36 ± 0.021	3.904ValLys: 3.904 ± 0.023	6.334ValLeu: 6.334 ± 0.029	1.529ValMet: 1.529 ± 0.013	2.608ValAsn: 2.608 ± 0.016	3.253ValPro: 3.253 ± 0.016	2.34ValGln: 2.34 ± 0.016	3.163ValArg: 3.163 ± 0.019	5.381ValSer: 5.381 ± 0.024	3.073ValThr: 3.073 ± 0.018	4.931ValVal: 4.931 ± 0.022	0.741ValTrp: 0.741 ± 0.009	1.913ValTyr: 1.913 ± 0.013	0.003ValXaa: 0.003 ± 0.001
Trp	0.827TrpAla: 0.827 ± 0.009	0.23TrpCys: 0.23 ± 0.004	0.716TrpAsp: 0.716 ± 0.009	0.753TrpGlu: 0.753 ± 0.009	0.526TrpPhe: 0.526 ± 0.007	0.751TrpGly: 0.751 ± 0.011	0.299TrpHis: 0.299 ± 0.006	0.701TrpIle: 0.701 ± 0.009	0.91TrpLys: 0.91 ± 0.01	1.202TrpLeu: 1.202 ± 0.012	0.346TrpMet: 0.346 ± 0.006	0.669TrpAsn: 0.669 ± 0.009	0.519TrpPro: 0.519 ± 0.007	0.453TrpGln: 0.453 ± 0.007	0.867TrpArg: 0.867 ± 0.009	0.971TrpSer: 0.971 ± 0.01	0.645TrpThr: 0.645 ± 0.008	0.755TrpVal: 0.755 ± 0.009	0.237TrpTrp: 0.237 ± 0.005	0.346TrpTyr: 0.346 ± 0.005	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.864TyrAla: 1.864 ± 0.015	0.621TyrCys: 0.621 ± 0.008	1.557TyrAsp: 1.557 ± 0.012	1.612TyrGlu: 1.612 ± 0.011	1.276TyrPhe: 1.276 ± 0.011	2.1TyrGly: 2.1 ± 0.018	0.74TyrHis: 0.74 ± 0.008	1.45TyrIle: 1.45 ± 0.012	1.498TyrLys: 1.498 ± 0.012	2.7TyrLeu: 2.7 ± 0.019	0.726TyrMet: 0.726 ± 0.008	1.325TyrAsn: 1.325 ± 0.012	1.271TyrPro: 1.271 ± 0.011	1.008TyrGln: 1.008 ± 0.01	1.529TyrArg: 1.529 ± 0.012	2.308TyrSer: 2.308 ± 0.019	1.323TyrThr: 1.323 ± 0.011	1.806TyrVal: 1.806 ± 0.013	0.406TyrTrp: 0.406 ± 0.007	0.988TyrTyr: 0.988 ± 0.012	0.001TyrXaa: 0.001 ± 0.0
Xaa	0.003XaaAla: 0.003 ± 0.0	0.001XaaCys: 0.001 ± 0.0	0.002XaaAsp: 0.002 ± 0.0	0.003XaaGlu: 0.003 ± 0.001	0.001XaaPhe: 0.001 ± 0.0	0.002XaaGly: 0.002 ± 0.0	0.001XaaHis: 0.001 ± 0.0	0.003XaaIle: 0.003 ± 0.001	0.003XaaLys: 0.003 ± 0.001	0.005XaaLeu: 0.005 ± 0.001	0.001XaaMet: 0.001 ± 0.0	0.002XaaAsn: 0.002 ± 0.0	0.004XaaPro: 0.004 ± 0.001	0.001XaaGln: 0.001 ± 0.0	0.002XaaArg: 0.002 ± 0.0	0.003XaaSer: 0.003 ± 0.001	0.003XaaThr: 0.003 ± 0.001	0.003XaaVal: 0.003 ± 0.001	0.0XaaTrp: 0.0 ± 0.0	0.001XaaTyr: 0.001 ± 0.0	0.077XaaXaa: 0.077 ± 0.006

Statistics based on 24106 proteins (10991492 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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