Amino acid dipepetide frequency for Sesamum indicum (Oriental sesame) (Sesamum orientale)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.05AlaAla: 7.05 ± 0.041
1.269AlaCys: 1.269 ± 0.012
3.416AlaAsp: 3.416 ± 0.017
4.599AlaGlu: 4.599 ± 0.025
2.763AlaPhe: 2.763 ± 0.017
4.399AlaGly: 4.399 ± 0.025
1.375AlaHis: 1.375 ± 0.012
3.809AlaIle: 3.809 ± 0.019
4.022AlaLys: 4.022 ± 0.022
6.773AlaLeu: 6.773 ± 0.033
1.791AlaMet: 1.791 ± 0.012
2.658AlaAsn: 2.658 ± 0.017
3.009AlaPro: 3.009 ± 0.02
2.282AlaGln: 2.282 ± 0.017
3.61AlaArg: 3.61 ± 0.02
6.155AlaSer: 6.155 ± 0.029
3.593AlaThr: 3.593 ± 0.019
5.089AlaVal: 5.089 ± 0.024
0.78AlaTrp: 0.78 ± 0.009
1.863AlaTyr: 1.863 ± 0.013
0.005AlaXaa: 0.005 ± 0.001
Cys
1.014CysAla: 1.014 ± 0.01
0.501CysCys: 0.501 ± 0.008
0.849CysAsp: 0.849 ± 0.009
0.895CysGlu: 0.895 ± 0.01
0.84CysPhe: 0.84 ± 0.008
1.379CysGly: 1.379 ± 0.014
0.46CysHis: 0.46 ± 0.007
0.988CysIle: 0.988 ± 0.009
1.094CysLys: 1.094 ± 0.013
1.793CysLeu: 1.793 ± 0.014
0.435CysMet: 0.435 ± 0.006
0.817CysAsn: 0.817 ± 0.009
0.926CysPro: 0.926 ± 0.012
0.597CysGln: 0.597 ± 0.009
1.107CysArg: 1.107 ± 0.012
1.788CysSer: 1.788 ± 0.015
0.85CysThr: 0.85 ± 0.009
1.022CysVal: 1.022 ± 0.011
0.226CysTrp: 0.226 ± 0.004
0.539CysTyr: 0.539 ± 0.007
0.001CysXaa: 0.001 ± 0.0
Asp
3.678AspAla: 3.678 ± 0.02
0.936AspCys: 0.936 ± 0.01
3.634AspAsp: 3.634 ± 0.026
4.15AspGlu: 4.15 ± 0.024
2.358AspPhe: 2.358 ± 0.016
3.828AspGly: 3.828 ± 0.02
1.286AspHis: 1.286 ± 0.011
3.036AspIle: 3.036 ± 0.02
2.769AspLys: 2.769 ± 0.017
4.977AspLeu: 4.977 ± 0.022
1.334AspMet: 1.334 ± 0.012
2.086AspAsn: 2.086 ± 0.014
2.707AspPro: 2.707 ± 0.014
1.782AspGln: 1.782 ± 0.012
2.511AspArg: 2.511 ± 0.018
4.282AspSer: 4.282 ± 0.021
2.184AspThr: 2.184 ± 0.015
3.688AspVal: 3.688 ± 0.018
0.704AspTrp: 0.704 ± 0.009
1.575AspTyr: 1.575 ± 0.013
0.002AspXaa: 0.002 ± 0.0
Glu
4.908GluAla: 4.908 ± 0.026
0.904GluCys: 0.904 ± 0.01
3.971GluAsp: 3.971 ± 0.025
6.163GluGlu: 6.163 ± 0.043
2.391GluPhe: 2.391 ± 0.016
3.705GluGly: 3.705 ± 0.02
1.273GluHis: 1.273 ± 0.012
3.754GluIle: 3.754 ± 0.023
4.896GluLys: 4.896 ± 0.032
6.041GluLeu: 6.041 ± 0.025
1.81GluMet: 1.81 ± 0.015
3.271GluAsn: 3.271 ± 0.025
2.19GluPro: 2.19 ± 0.015
2.235GluGln: 2.235 ± 0.014
3.508GluArg: 3.508 ± 0.022
4.646GluSer: 4.646 ± 0.024
3.096GluThr: 3.096 ± 0.02
4.201GluVal: 4.201 ± 0.021
0.777GluTrp: 0.777 ± 0.01
1.707GluTyr: 1.707 ± 0.014
0.002GluXaa: 0.002 ± 0.001
Phe
2.577PheAla: 2.577 ± 0.017
0.852PheCys: 0.852 ± 0.008
2.287PheAsp: 2.287 ± 0.014
2.2PheGlu: 2.2 ± 0.016
1.872PhePhe: 1.872 ± 0.017
2.977PheGly: 2.977 ± 0.019
1.093PheHis: 1.093 ± 0.01
1.972PheIle: 1.972 ± 0.016
1.977PheLys: 1.977 ± 0.013
4.28PheLeu: 4.28 ± 0.023
0.953PheMet: 0.953 ± 0.01
1.652PheAsn: 1.652 ± 0.014
2.099PhePro: 2.099 ± 0.016
1.553PheGln: 1.553 ± 0.013
2.117PheArg: 2.117 ± 0.014
4.028PheSer: 4.028 ± 0.022
2.002PheThr: 2.002 ± 0.015
2.643PheVal: 2.643 ± 0.017
0.542PheTrp: 0.542 ± 0.007
1.259PheTyr: 1.259 ± 0.012
0.001PheXaa: 0.001 ± 0.0
Gly
4.066GlyAla: 4.066 ± 0.021
1.259GlyCys: 1.259 ± 0.012
3.404GlyAsp: 3.404 ± 0.019
3.751GlyGlu: 3.751 ± 0.02
3.085GlyPhe: 3.085 ± 0.02
5.534GlyGly: 5.534 ± 0.041
1.528GlyHis: 1.528 ± 0.014
3.582GlyIle: 3.582 ± 0.021
4.094GlyLys: 4.094 ± 0.021
5.94GlyLeu: 5.94 ± 0.028
1.493GlyMet: 1.493 ± 0.014
3.115GlyAsn: 3.115 ± 0.021
2.632GlyPro: 2.632 ± 0.017
2.096GlyGln: 2.096 ± 0.016
3.755GlyArg: 3.755 ± 0.023
6.041GlySer: 6.041 ± 0.028
3.223GlyThr: 3.223 ± 0.022
4.258GlyVal: 4.258 ± 0.021
0.917GlyTrp: 0.917 ± 0.01
2.093GlyTyr: 2.093 ± 0.015
0.005GlyXaa: 0.005 ± 0.001
His
1.48HisAla: 1.48 ± 0.012
0.514HisCys: 0.514 ± 0.006
1.189HisAsp: 1.189 ± 0.013
1.314HisGlu: 1.314 ± 0.011
1.057HisPhe: 1.057 ± 0.01
1.712HisGly: 1.712 ± 0.013
0.988HisHis: 0.988 ± 0.012
1.213HisIle: 1.213 ± 0.012
1.194HisLys: 1.194 ± 0.011
2.386HisLeu: 2.386 ± 0.017
0.572HisMet: 0.572 ± 0.008
0.958HisAsn: 0.958 ± 0.011
1.389HisPro: 1.389 ± 0.011
1.049HisGln: 1.049 ± 0.01
1.374HisArg: 1.374 ± 0.012
1.955HisSer: 1.955 ± 0.013
0.959HisThr: 0.959 ± 0.01
1.513HisVal: 1.513 ± 0.014
0.308HisTrp: 0.308 ± 0.006
0.706HisTyr: 0.706 ± 0.009
0.001HisXaa: 0.001 ± 0.0
Ile
3.61IleAla: 3.61 ± 0.018
1.091IleCys: 1.091 ± 0.011
2.884IleAsp: 2.884 ± 0.017
3.116IleGlu: 3.116 ± 0.02
2.215IlePhe: 2.215 ± 0.015
3.294IleGly: 3.294 ± 0.02
1.312IleHis: 1.312 ± 0.011
2.721IleIle: 2.721 ± 0.019
2.846IleLys: 2.846 ± 0.016
5.251IleLeu: 5.251 ± 0.027
1.161IleMet: 1.161 ± 0.011
2.157IleAsn: 2.157 ± 0.016
2.934IlePro: 2.934 ± 0.021
1.986IleGln: 1.986 ± 0.015
2.683IleArg: 2.683 ± 0.016
4.884IleSer: 4.884 ± 0.025
2.557IleThr: 2.557 ± 0.015
3.384IleVal: 3.384 ± 0.021
0.692IleTrp: 0.692 ± 0.009
1.5IleTyr: 1.5 ± 0.013
0.002IleXaa: 0.002 ± 0.0
Lys
4.066LysAla: 4.066 ± 0.022
0.947LysCys: 0.947 ± 0.009
3.283LysAsp: 3.283 ± 0.019
4.562LysGlu: 4.562 ± 0.03
2.178LysPhe: 2.178 ± 0.014
3.519LysGly: 3.519 ± 0.02
1.345LysHis: 1.345 ± 0.011
3.152LysIle: 3.152 ± 0.018
4.608LysLys: 4.608 ± 0.031
5.95LysLeu: 5.95 ± 0.026
1.508LysMet: 1.508 ± 0.013
2.716LysAsn: 2.716 ± 0.018
2.751LysPro: 2.751 ± 0.017
2.315LysGln: 2.315 ± 0.017
3.624LysArg: 3.624 ± 0.022
4.657LysSer: 4.657 ± 0.028
2.805LysThr: 2.805 ± 0.018
3.764LysVal: 3.764 ± 0.023
0.804LysTrp: 0.804 ± 0.009
1.693LysTyr: 1.693 ± 0.013
0.002LysXaa: 0.002 ± 0.0
Leu
6.657LeuAla: 6.657 ± 0.031
1.773LeuCys: 1.773 ± 0.015
5.056LeuAsp: 5.056 ± 0.023
6.356LeuGlu: 6.356 ± 0.032
3.736LeuPhe: 3.736 ± 0.02
5.782LeuGly: 5.782 ± 0.028
2.566LeuHis: 2.566 ± 0.017
4.621LeuIle: 4.621 ± 0.028
6.079LeuLys: 6.079 ± 0.026
9.803LeuLeu: 9.803 ± 0.047
2.162LeuMet: 2.162 ± 0.014
3.84LeuAsn: 3.84 ± 0.02
5.231LeuPro: 5.231 ± 0.024
4.339LeuGln: 4.339 ± 0.022
5.51LeuArg: 5.51 ± 0.025
8.492LeuSer: 8.492 ± 0.039
4.287LeuThr: 4.287 ± 0.022
6.249LeuVal: 6.249 ± 0.031
1.121LeuTrp: 1.121 ± 0.013
2.533LeuTyr: 2.533 ± 0.019
0.004LeuXaa: 0.004 ± 0.001
Met
2.161MetAla: 2.161 ± 0.012
0.322MetCys: 0.322 ± 0.006
1.439MetAsp: 1.439 ± 0.011
1.979MetGlu: 1.979 ± 0.013
0.794MetPhe: 0.794 ± 0.008
1.653MetGly: 1.653 ± 0.013
0.547MetHis: 0.547 ± 0.007
1.186MetIle: 1.186 ± 0.01
1.61MetLys: 1.61 ± 0.013
2.191MetLeu: 2.191 ± 0.014
0.687MetMet: 0.687 ± 0.009
1.016MetAsn: 1.016 ± 0.011
1.057MetPro: 1.057 ± 0.011
0.963MetGln: 0.963 ± 0.011
1.233MetArg: 1.233 ± 0.01
1.761MetSer: 1.761 ± 0.011
1.029MetThr: 1.029 ± 0.008
1.626MetVal: 1.626 ± 0.014
0.268MetTrp: 0.268 ± 0.006
0.59MetTyr: 0.59 ± 0.008
0.001MetXaa: 0.001 ± 0.0
Asn
2.778AsnAla: 2.778 ± 0.017
0.847AsnCys: 0.847 ± 0.01
2.095AsnAsp: 2.095 ± 0.015
2.524AsnGlu: 2.524 ± 0.017
1.887AsnPhe: 1.887 ± 0.015
3.233AsnGly: 3.233 ± 0.021
1.076AsnHis: 1.076 ± 0.011
2.382AsnIle: 2.382 ± 0.015
2.32AsnLys: 2.32 ± 0.014
4.446AsnLeu: 4.446 ± 0.024
1.095AsnMet: 1.095 ± 0.01
2.063AsnAsn: 2.063 ± 0.019
2.372AsnPro: 2.372 ± 0.017
1.689AsnGln: 1.689 ± 0.013
2.08AsnArg: 2.08 ± 0.013
3.991AsnSer: 3.991 ± 0.022
1.892AsnThr: 1.892 ± 0.012
2.787AsnVal: 2.787 ± 0.016
0.564AsnTrp: 0.564 ± 0.008
1.345AsnTyr: 1.345 ± 0.012
0.002AsnXaa: 0.002 ± 0.0
Pro
3.257ProAla: 3.257 ± 0.019
0.762ProCys: 0.762 ± 0.009
2.635ProAsp: 2.635 ± 0.017
3.233ProGlu: 3.233 ± 0.02
2.019ProPhe: 2.019 ± 0.014
2.947ProGly: 2.947 ± 0.022
1.154ProHis: 1.154 ± 0.011
2.297ProIle: 2.297 ± 0.016
2.719ProLys: 2.719 ± 0.019
4.424ProLeu: 4.424 ± 0.02
0.995ProMet: 0.995 ± 0.011
2.242ProAsn: 2.242 ± 0.015
4.227ProPro: 4.227 ± 0.064
1.894ProGln: 1.894 ± 0.017
2.523ProArg: 2.523 ± 0.018
5.081ProSer: 5.081 ± 0.027
2.698ProThr: 2.698 ± 0.018
3.241ProVal: 3.241 ± 0.016
0.622ProTrp: 0.622 ± 0.009
1.341ProTyr: 1.341 ± 0.013
0.003ProXaa: 0.003 ± 0.0
Gln
2.453GlnAla: 2.453 ± 0.019
0.573GlnCys: 0.573 ± 0.009
1.733GlnAsp: 1.733 ± 0.014
2.597GlnGlu: 2.597 ± 0.017
1.368GlnPhe: 1.368 ± 0.011
2.096GlnGly: 2.096 ± 0.015
0.931GlnHis: 0.931 ± 0.009
2.003GlnIle: 2.003 ± 0.014
2.428GlnLys: 2.428 ± 0.017
3.699GlnLeu: 3.699 ± 0.019
0.998GlnMet: 0.998 ± 0.01
1.797GlnAsn: 1.797 ± 0.014
1.82GlnPro: 1.82 ± 0.016
2.071GlnGln: 2.071 ± 0.027
2.168GlnArg: 2.168 ± 0.014
2.833GlnSer: 2.833 ± 0.016
1.741GlnThr: 1.741 ± 0.013
2.355GlnVal: 2.355 ± 0.015
0.459GlnTrp: 0.459 ± 0.006
0.975GlnTyr: 0.975 ± 0.011
0.002GlnXaa: 0.002 ± 0.0
Arg
3.546ArgAla: 3.546 ± 0.02
0.951ArgCys: 0.951 ± 0.01
2.75ArgAsp: 2.75 ± 0.019
3.439ArgGlu: 3.439 ± 0.022
2.183ArgPhe: 2.183 ± 0.015
3.324ArgGly: 3.324 ± 0.019
1.319ArgHis: 1.319 ± 0.011
2.973ArgIle: 2.973 ± 0.018
3.959ArgLys: 3.959 ± 0.021
5.104ArgLeu: 5.104 ± 0.024
1.353ArgMet: 1.353 ± 0.012
2.546ArgAsn: 2.546 ± 0.016
2.507ArgPro: 2.507 ± 0.017
1.946ArgGln: 1.946 ± 0.014
4.199ArgArg: 4.199 ± 0.031
4.475ArgSer: 4.475 ± 0.027
2.565ArgThr: 2.565 ± 0.016
3.363ArgVal: 3.363 ± 0.016
0.756ArgTrp: 0.756 ± 0.008
1.478ArgTyr: 1.478 ± 0.012
0.003ArgXaa: 0.003 ± 0.001
Ser
5.799SerAla: 5.799 ± 0.026
1.723SerCys: 1.723 ± 0.015
4.511SerAsp: 4.511 ± 0.024
4.891SerGlu: 4.891 ± 0.024
3.79SerPhe: 3.79 ± 0.022
6.15SerGly: 6.15 ± 0.028
1.99SerHis: 1.99 ± 0.013
4.432SerIle: 4.432 ± 0.022
4.793SerLys: 4.793 ± 0.025
8.34SerLeu: 8.34 ± 0.033
2.047SerMet: 2.047 ± 0.014
3.915SerAsn: 3.915 ± 0.021
4.737SerPro: 4.737 ± 0.035
3.022SerGln: 3.022 ± 0.021
4.74SerArg: 4.74 ± 0.026
10.895SerSer: 10.895 ± 0.055
4.713SerThr: 4.713 ± 0.023
5.265SerVal: 5.265 ± 0.025
1.173SerTrp: 1.173 ± 0.012
2.294SerTyr: 2.294 ± 0.016
0.003SerXaa: 0.003 ± 0.001
Thr
3.558ThrAla: 3.558 ± 0.02
0.905ThrCys: 0.905 ± 0.01
2.304ThrAsp: 2.304 ± 0.014
2.812ThrGlu: 2.812 ± 0.018
1.967ThrPhe: 1.967 ± 0.013
3.302ThrGly: 3.302 ± 0.018
1.02ThrHis: 1.02 ± 0.011
2.644ThrIle: 2.644 ± 0.015
2.529ThrLys: 2.529 ± 0.015
4.558ThrLeu: 4.558 ± 0.023
1.115ThrMet: 1.115 ± 0.01
2.012ThrAsn: 2.012 ± 0.012
2.679ThrPro: 2.679 ± 0.019
1.479ThrGln: 1.479 ± 0.012
2.438ThrArg: 2.438 ± 0.016
4.6ThrSer: 4.6 ± 0.026
2.827ThrThr: 2.827 ± 0.019
3.324ThrVal: 3.324 ± 0.018
0.624ThrTrp: 0.624 ± 0.008
1.368ThrTyr: 1.368 ± 0.011
0.002ThrXaa: 0.002 ± 0.0
Val
4.959ValAla: 4.959 ± 0.024
1.139ValCys: 1.139 ± 0.012
3.794ValAsp: 3.794 ± 0.02
4.499ValGlu: 4.499 ± 0.021
2.631ValPhe: 2.631 ± 0.017
4.183ValGly: 4.183 ± 0.022
1.53ValHis: 1.53 ± 0.013
3.36ValIle: 3.36 ± 0.021
3.904ValLys: 3.904 ± 0.023
6.334ValLeu: 6.334 ± 0.029
1.529ValMet: 1.529 ± 0.013
2.608ValAsn: 2.608 ± 0.016
3.253ValPro: 3.253 ± 0.016
2.34ValGln: 2.34 ± 0.016
3.163ValArg: 3.163 ± 0.019
5.381ValSer: 5.381 ± 0.024
3.073ValThr: 3.073 ± 0.018
4.931ValVal: 4.931 ± 0.022
0.741ValTrp: 0.741 ± 0.009
1.913ValTyr: 1.913 ± 0.013
0.003ValXaa: 0.003 ± 0.001
Trp
0.827TrpAla: 0.827 ± 0.009
0.23TrpCys: 0.23 ± 0.004
0.716TrpAsp: 0.716 ± 0.009
0.753TrpGlu: 0.753 ± 0.009
0.526TrpPhe: 0.526 ± 0.007
0.751TrpGly: 0.751 ± 0.011
0.299TrpHis: 0.299 ± 0.006
0.701TrpIle: 0.701 ± 0.009
0.91TrpLys: 0.91 ± 0.01
1.202TrpLeu: 1.202 ± 0.012
0.346TrpMet: 0.346 ± 0.006
0.669TrpAsn: 0.669 ± 0.009
0.519TrpPro: 0.519 ± 0.007
0.453TrpGln: 0.453 ± 0.007
0.867TrpArg: 0.867 ± 0.009
0.971TrpSer: 0.971 ± 0.01
0.645TrpThr: 0.645 ± 0.008
0.755TrpVal: 0.755 ± 0.009
0.237TrpTrp: 0.237 ± 0.005
0.346TrpTyr: 0.346 ± 0.005
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.864TyrAla: 1.864 ± 0.015
0.621TyrCys: 0.621 ± 0.008
1.557TyrAsp: 1.557 ± 0.012
1.612TyrGlu: 1.612 ± 0.011
1.276TyrPhe: 1.276 ± 0.011
2.1TyrGly: 2.1 ± 0.018
0.74TyrHis: 0.74 ± 0.008
1.45TyrIle: 1.45 ± 0.012
1.498TyrLys: 1.498 ± 0.012
2.7TyrLeu: 2.7 ± 0.019
0.726TyrMet: 0.726 ± 0.008
1.325TyrAsn: 1.325 ± 0.012
1.271TyrPro: 1.271 ± 0.011
1.008TyrGln: 1.008 ± 0.01
1.529TyrArg: 1.529 ± 0.012
2.308TyrSer: 2.308 ± 0.019
1.323TyrThr: 1.323 ± 0.011
1.806TyrVal: 1.806 ± 0.013
0.406TyrTrp: 0.406 ± 0.007
0.988TyrTyr: 0.988 ± 0.012
0.001TyrXaa: 0.001 ± 0.0
Xaa
0.003XaaAla: 0.003 ± 0.0
0.001XaaCys: 0.001 ± 0.0
0.002XaaAsp: 0.002 ± 0.0
0.003XaaGlu: 0.003 ± 0.001
0.001XaaPhe: 0.001 ± 0.0
0.002XaaGly: 0.002 ± 0.0
0.001XaaHis: 0.001 ± 0.0
0.003XaaIle: 0.003 ± 0.001
0.003XaaLys: 0.003 ± 0.001
0.005XaaLeu: 0.005 ± 0.001
0.001XaaMet: 0.001 ± 0.0
0.002XaaAsn: 0.002 ± 0.0
0.004XaaPro: 0.004 ± 0.001
0.001XaaGln: 0.001 ± 0.0
0.002XaaArg: 0.002 ± 0.0
0.003XaaSer: 0.003 ± 0.001
0.003XaaThr: 0.003 ± 0.001
0.003XaaVal: 0.003 ± 0.001
0.0XaaTrp: 0.0 ± 0.0
0.001XaaTyr: 0.001 ± 0.0
0.077XaaXaa: 0.077 ± 0.006
Statistics based on 24106 proteins (10991492 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski