Amino acid dipepetide frequency for Opisthocomus hoazin (Hoatzin) (Phasianus hoazin)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.664AlaAla: 5.664 ± 0.046	1.354AlaCys: 1.354 ± 0.02	3.03AlaAsp: 3.03 ± 0.028	4.586AlaGlu: 4.586 ± 0.038	2.65AlaPhe: 2.65 ± 0.022	3.903AlaGly: 3.903 ± 0.037	1.369AlaHis: 1.369 ± 0.018	3.079AlaIle: 3.079 ± 0.032	3.718AlaLys: 3.718 ± 0.029	6.538AlaLeu: 6.538 ± 0.047	1.489AlaMet: 1.489 ± 0.017	2.258AlaAsn: 2.258 ± 0.022	2.866AlaPro: 2.866 ± 0.035	2.688AlaGln: 2.688 ± 0.029	3.1AlaArg: 3.1 ± 0.027	5.133AlaSer: 5.133 ± 0.032	3.274AlaThr: 3.274 ± 0.029	5.129AlaVal: 5.129 ± 0.034	0.72AlaTrp: 0.72 ± 0.015	1.666AlaTyr: 1.666 ± 0.019	0.001AlaXaa: 0.001 ± 0.0
Cys	1.213CysAla: 1.213 ± 0.018	0.675CysCys: 0.675 ± 0.015	1.08CysAsp: 1.08 ± 0.02	1.336CysGlu: 1.336 ± 0.022	0.958CysPhe: 0.958 ± 0.015	1.482CysGly: 1.482 ± 0.025	0.635CysHis: 0.635 ± 0.012	1.161CysIle: 1.161 ± 0.019	1.392CysLys: 1.392 ± 0.019	2.216CysLeu: 2.216 ± 0.026	0.459CysMet: 0.459 ± 0.01	0.93CysAsn: 0.93 ± 0.016	1.259CysPro: 1.259 ± 0.025	1.067CysGln: 1.067 ± 0.021	1.234CysArg: 1.234 ± 0.018	2.038CysSer: 2.038 ± 0.028	1.205CysThr: 1.205 ± 0.018	1.439CysVal: 1.439 ± 0.022	0.301CysTrp: 0.301 ± 0.009	0.696CysTyr: 0.696 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	2.948AspAla: 2.948 ± 0.025	1.132AspCys: 1.132 ± 0.019	2.873AspAsp: 2.873 ± 0.034	3.675AspGlu: 3.675 ± 0.037	2.299AspPhe: 2.299 ± 0.022	3.387AspGly: 3.387 ± 0.031	1.168AspHis: 1.168 ± 0.014	3.108AspIle: 3.108 ± 0.028	2.801AspLys: 2.801 ± 0.027	5.062AspLeu: 5.062 ± 0.036	1.162AspMet: 1.162 ± 0.016	1.963AspAsn: 1.963 ± 0.025	2.582AspPro: 2.582 ± 0.025	1.856AspGln: 1.856 ± 0.019	2.406AspArg: 2.406 ± 0.029	4.06AspSer: 4.06 ± 0.033	2.523AspThr: 2.523 ± 0.022	3.26AspVal: 3.26 ± 0.029	0.666AspTrp: 0.666 ± 0.012	1.668AspTyr: 1.668 ± 0.02	0.0AspXaa: 0.0 ± 0.0
Glu	4.727GluAla: 4.727 ± 0.034	1.338GluCys: 1.338 ± 0.03	4.542GluAsp: 4.542 ± 0.037	7.802GluGlu: 7.802 ± 0.075	2.229GluPhe: 2.229 ± 0.021	3.999GluGly: 3.999 ± 0.03	1.569GluHis: 1.569 ± 0.018	3.544GluIle: 3.544 ± 0.031	5.731GluLys: 5.731 ± 0.049	6.295GluLeu: 6.295 ± 0.056	1.787GluMet: 1.787 ± 0.019	3.483GluAsn: 3.483 ± 0.03	2.469GluPro: 2.469 ± 0.029	3.159GluGln: 3.159 ± 0.03	3.963GluArg: 3.963 ± 0.047	4.467GluSer: 4.467 ± 0.035	3.583GluThr: 3.583 ± 0.033	4.401GluVal: 4.401 ± 0.031	0.75GluTrp: 0.75 ± 0.011	1.847GluTyr: 1.847 ± 0.021	0.0GluXaa: 0.0 ± 0.0
Phe	2.174PheAla: 2.174 ± 0.026	1.025PheCys: 1.025 ± 0.016	1.87PheAsp: 1.87 ± 0.019	2.204PheGlu: 2.204 ± 0.023	2.037PhePhe: 2.037 ± 0.028	2.281PheGly: 2.281 ± 0.022	1.095PheHis: 1.095 ± 0.014	2.13PheIle: 2.13 ± 0.024	2.276PheLys: 2.276 ± 0.023	4.227PheLeu: 4.227 ± 0.034	0.794PheMet: 0.794 ± 0.014	1.52PheAsn: 1.52 ± 0.017	1.942PhePro: 1.942 ± 0.023	1.836PheGln: 1.836 ± 0.02	2.05PheArg: 2.05 ± 0.022	3.506PheSer: 3.506 ± 0.026	2.38PheThr: 2.38 ± 0.024	2.417PheVal: 2.417 ± 0.024	0.528PheTrp: 0.528 ± 0.011	1.343PheTyr: 1.343 ± 0.02	0.0PheXaa: 0.0 ± 0.0
Gly	3.554GlyAla: 3.554 ± 0.034	1.305GlyCys: 1.305 ± 0.02	2.976GlyAsp: 2.976 ± 0.029	3.748GlyGlu: 3.748 ± 0.043	2.54GlyPhe: 2.54 ± 0.031	3.823GlyGly: 3.823 ± 0.045	1.518GlyHis: 1.518 ± 0.02	3.097GlyIle: 3.097 ± 0.031	4.099GlyLys: 4.099 ± 0.041	5.189GlyLeu: 5.189 ± 0.05	1.362GlyMet: 1.362 ± 0.02	2.619GlyAsn: 2.619 ± 0.026	2.696GlyPro: 2.696 ± 0.064	2.433GlyGln: 2.433 ± 0.025	3.313GlyArg: 3.313 ± 0.037	4.934GlySer: 4.934 ± 0.046	3.373GlyThr: 3.373 ± 0.034	3.487GlyVal: 3.487 ± 0.03	0.765GlyTrp: 0.765 ± 0.016	1.872GlyTyr: 1.872 ± 0.021	0.0GlyXaa: 0.0 ± 0.0
His	1.35HisAla: 1.35 ± 0.017	0.722HisCys: 0.722 ± 0.014	0.926HisAsp: 0.926 ± 0.014	1.369HisGlu: 1.369 ± 0.017	1.1HisPhe: 1.1 ± 0.015	1.498HisGly: 1.498 ± 0.019	0.833HisHis: 0.833 ± 0.018	1.332HisIle: 1.332 ± 0.017	1.396HisLys: 1.396 ± 0.019	2.826HisLeu: 2.826 ± 0.025	0.594HisMet: 0.594 ± 0.011	0.958HisAsn: 0.958 ± 0.013	1.457HisPro: 1.457 ± 0.019	1.184HisGln: 1.184 ± 0.018	1.467HisArg: 1.467 ± 0.019	2.176HisSer: 2.176 ± 0.022	1.319HisThr: 1.319 ± 0.017	1.55HisVal: 1.55 ± 0.018	0.494HisTrp: 0.494 ± 0.008	0.863HisTyr: 0.863 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	3.082IleAla: 3.082 ± 0.027	1.236IleCys: 1.236 ± 0.019	2.369IleAsp: 2.369 ± 0.026	2.9IleGlu: 2.9 ± 0.028	2.2IlePhe: 2.2 ± 0.024	2.476IleGly: 2.476 ± 0.03	1.405IleHis: 1.405 ± 0.017	2.764IleIle: 2.764 ± 0.03	3.075IleLys: 3.075 ± 0.031	5.001IleLeu: 5.001 ± 0.036	1.082IleMet: 1.082 ± 0.015	2.169IleAsn: 2.169 ± 0.02	2.839IlePro: 2.839 ± 0.027	2.48IleGln: 2.48 ± 0.023	2.661IleArg: 2.661 ± 0.024	4.088IleSer: 4.088 ± 0.029	2.842IleThr: 2.842 ± 0.026	2.974IleVal: 2.974 ± 0.029	0.587IleTrp: 0.587 ± 0.012	1.626IleTyr: 1.626 ± 0.02	0.0IleXaa: 0.0 ± 0.0
Lys	4.31LysAla: 4.31 ± 0.037	1.28LysCys: 1.28 ± 0.021	3.489LysAsp: 3.489 ± 0.03	5.881LysGlu: 5.881 ± 0.059	2.09LysPhe: 2.09 ± 0.023	3.514LysGly: 3.514 ± 0.042	1.704LysHis: 1.704 ± 0.022	3.239LysIle: 3.239 ± 0.028	5.56LysLys: 5.56 ± 0.055	5.862LysLeu: 5.862 ± 0.043	1.585LysMet: 1.585 ± 0.02	2.82LysAsn: 2.82 ± 0.029	3.023LysPro: 3.023 ± 0.032	3.032LysGln: 3.032 ± 0.029	3.564LysArg: 3.564 ± 0.031	4.264LysSer: 4.264 ± 0.039	3.444LysThr: 3.444 ± 0.032	3.772LysVal: 3.772 ± 0.028	0.69LysTrp: 0.69 ± 0.013	1.9LysTyr: 1.9 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	6.241LeuAla: 6.241 ± 0.047	2.213LeuCys: 2.213 ± 0.027	5.053LeuAsp: 5.053 ± 0.043	7.026LeuGlu: 7.026 ± 0.065	3.646LeuPhe: 3.646 ± 0.034	5.203LeuGly: 5.203 ± 0.036	2.725LeuHis: 2.725 ± 0.026	4.319LeuIle: 4.319 ± 0.033	6.583LeuLys: 6.583 ± 0.048	10.055LeuLeu: 10.055 ± 0.064	2.042LeuMet: 2.042 ± 0.022	3.898LeuAsn: 3.898 ± 0.031	5.37LeuPro: 5.37 ± 0.042	5.551LeuGln: 5.551 ± 0.043	5.171LeuArg: 5.171 ± 0.037	7.892LeuSer: 7.892 ± 0.044	4.986LeuThr: 4.986 ± 0.034	5.603LeuVal: 5.603 ± 0.042	1.102LeuTrp: 1.102 ± 0.016	2.828LeuTyr: 2.828 ± 0.025	0.001LeuXaa: 0.001 ± 0.0
Met	1.615MetAla: 1.615 ± 0.019	0.447MetCys: 0.447 ± 0.012	1.283MetAsp: 1.283 ± 0.015	1.862MetGlu: 1.862 ± 0.021	0.835MetPhe: 0.835 ± 0.014	1.242MetGly: 1.242 ± 0.02	0.536MetHis: 0.536 ± 0.009	0.998MetIle: 0.998 ± 0.014	1.612MetLys: 1.612 ± 0.017	2.045MetLeu: 2.045 ± 0.02	0.606MetMet: 0.606 ± 0.012	1.017MetAsn: 1.017 ± 0.015	1.014MetPro: 1.014 ± 0.016	1.025MetGln: 1.025 ± 0.018	1.176MetArg: 1.176 ± 0.016	1.56MetSer: 1.56 ± 0.019	1.162MetThr: 1.162 ± 0.017	1.415MetVal: 1.415 ± 0.018	0.252MetTrp: 0.252 ± 0.007	0.678MetTyr: 0.678 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	2.375AsnAla: 2.375 ± 0.022	0.996AsnCys: 0.996 ± 0.017	1.727AsnAsp: 1.727 ± 0.019	2.595AsnGlu: 2.595 ± 0.025	1.651AsnPhe: 1.651 ± 0.02	2.866AsnGly: 2.866 ± 0.03	0.996AsnHis: 0.996 ± 0.014	2.484AsnIle: 2.484 ± 0.023	2.599AsnLys: 2.599 ± 0.028	4.212AsnLeu: 4.212 ± 0.034	0.992AsnMet: 0.992 ± 0.013	1.815AsnAsn: 1.815 ± 0.022	2.274AsnPro: 2.274 ± 0.026	1.707AsnGln: 1.707 ± 0.02	2.07AsnArg: 2.07 ± 0.019	3.448AsnSer: 3.448 ± 0.028	2.225AsnThr: 2.225 ± 0.023	2.534AsnVal: 2.534 ± 0.024	0.503AsnTrp: 0.503 ± 0.01	1.315AsnTyr: 1.315 ± 0.015	0.001AsnXaa: 0.001 ± 0.0
Pro	3.619ProAla: 3.619 ± 0.032	1.056ProCys: 1.056 ± 0.021	2.563ProAsp: 2.563 ± 0.021	3.755ProGlu: 3.755 ± 0.036	1.9ProPhe: 1.9 ± 0.022	3.571ProGly: 3.571 ± 0.088	1.212ProHis: 1.212 ± 0.018	1.919ProIle: 1.919 ± 0.019	2.722ProLys: 2.722 ± 0.028	4.55ProLeu: 4.55 ± 0.034	0.919ProMet: 0.919 ± 0.014	1.853ProAsn: 1.853 ± 0.022	3.981ProPro: 3.981 ± 0.055	2.217ProGln: 2.217 ± 0.028	2.554ProArg: 2.554 ± 0.025	4.853ProSer: 4.853 ± 0.045	2.546ProThr: 2.546 ± 0.029	3.679ProVal: 3.679 ± 0.034	0.566ProTrp: 0.566 ± 0.011	1.435ProTyr: 1.435 ± 0.018	0.0ProXaa: 0.0 ± 0.0
Gln	2.983GlnAla: 2.983 ± 0.029	0.994GlnCys: 0.994 ± 0.018	2.182GlnAsp: 2.182 ± 0.021	3.609GlnGlu: 3.609 ± 0.035	1.487GlnPhe: 1.487 ± 0.016	2.477GlnGly: 2.477 ± 0.027	1.289GlnHis: 1.289 ± 0.019	2.267GlnIle: 2.267 ± 0.023	3.209GlnLys: 3.209 ± 0.037	4.566GlnLeu: 4.566 ± 0.038	1.104GlnMet: 1.104 ± 0.015	2.039GlnAsn: 2.039 ± 0.022	2.217GlnPro: 2.217 ± 0.024	2.907GlnGln: 2.907 ± 0.049	2.622GlnArg: 2.622 ± 0.029	3.123GlnSer: 3.123 ± 0.032	2.351GlnThr: 2.351 ± 0.023	2.723GlnVal: 2.723 ± 0.024	0.531GlnTrp: 0.531 ± 0.011	1.327GlnTyr: 1.327 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	3.085ArgAla: 3.085 ± 0.029	1.135ArgCys: 1.135 ± 0.019	2.592ArgAsp: 2.592 ± 0.027	3.869ArgGlu: 3.869 ± 0.038	2.009ArgPhe: 2.009 ± 0.022	2.859ArgGly: 2.859 ± 0.032	1.436ArgHis: 1.436 ± 0.019	2.623ArgIle: 2.623 ± 0.023	4.182ArgLys: 4.182 ± 0.043	5.209ArgLeu: 5.209 ± 0.038	1.158ArgMet: 1.158 ± 0.015	2.271ArgAsn: 2.271 ± 0.021	2.36ArgPro: 2.36 ± 0.023	2.51ArgGln: 2.51 ± 0.027	3.617ArgArg: 3.617 ± 0.033	3.934ArgSer: 3.934 ± 0.045	2.672ArgThr: 2.672 ± 0.024	3.065ArgVal: 3.065 ± 0.026	0.642ArgTrp: 0.642 ± 0.012	1.608ArgTyr: 1.608 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	5.09SerAla: 5.09 ± 0.039	1.878SerCys: 1.878 ± 0.023	4.016SerAsp: 4.016 ± 0.035	5.099SerGlu: 5.099 ± 0.04	3.121SerPhe: 3.121 ± 0.025	4.882SerGly: 4.882 ± 0.042	1.997SerHis: 1.997 ± 0.022	3.57SerIle: 3.57 ± 0.026	4.539SerLys: 4.539 ± 0.034	7.986SerLeu: 7.986 ± 0.052	1.627SerMet: 1.627 ± 0.019	3.143SerAsn: 3.143 ± 0.026	4.959SerPro: 4.959 ± 0.049	3.53SerGln: 3.53 ± 0.032	4.058SerArg: 4.058 ± 0.043	8.941SerSer: 8.941 ± 0.086	4.463SerThr: 4.463 ± 0.035	5.177SerVal: 5.177 ± 0.037	0.988SerTrp: 0.988 ± 0.015	2.256SerTyr: 2.256 ± 0.02	0.0SerXaa: 0.0 ± 0.0
Thr	3.789ThrAla: 3.789 ± 0.029	1.339ThrCys: 1.339 ± 0.023	2.729ThrAsp: 2.729 ± 0.026	3.745ThrGlu: 3.745 ± 0.031	2.201ThrPhe: 2.201 ± 0.024	3.425ThrGly: 3.425 ± 0.033	1.168ThrHis: 1.168 ± 0.017	2.585ThrIle: 2.585 ± 0.024	2.891ThrLys: 2.891 ± 0.021	5.132ThrLeu: 5.132 ± 0.037	1.214ThrMet: 1.214 ± 0.016	1.951ThrAsn: 1.951 ± 0.022	2.989ThrPro: 2.989 ± 0.034	2.1ThrGln: 2.1 ± 0.02	2.365ThrArg: 2.365 ± 0.022	4.569ThrSer: 4.569 ± 0.036	2.95ThrThr: 2.95 ± 0.034	4.147ThrVal: 4.147 ± 0.033	0.667ThrTrp: 0.667 ± 0.014	1.559ThrTyr: 1.559 ± 0.019	0.001ThrXaa: 0.001 ± 0.0
Val	4.123ValAla: 4.123 ± 0.032	1.602ValCys: 1.602 ± 0.024	3.15ValAsp: 3.15 ± 0.029	4.008ValGlu: 4.008 ± 0.028	2.797ValPhe: 2.797 ± 0.025	3.364ValGly: 3.364 ± 0.035	1.612ValHis: 1.612 ± 0.018	3.346ValIle: 3.346 ± 0.033	3.988ValLys: 3.988 ± 0.03	6.369ValLeu: 6.369 ± 0.038	1.407ValMet: 1.407 ± 0.017	2.641ValAsn: 2.641 ± 0.024	3.411ValPro: 3.411 ± 0.03	2.853ValGln: 2.853 ± 0.023	3.056ValArg: 3.056 ± 0.026	5.002ValSer: 5.002 ± 0.039	3.89ValThr: 3.89 ± 0.032	4.431ValVal: 4.431 ± 0.036	0.743ValTrp: 0.743 ± 0.013	1.884ValTyr: 1.884 ± 0.022	0.0ValXaa: 0.0 ± 0.0
Trp	0.674TrpAla: 0.674 ± 0.011	0.251TrpCys: 0.251 ± 0.007	0.676TrpAsp: 0.676 ± 0.015	0.785TrpGlu: 0.785 ± 0.013	0.463TrpPhe: 0.463 ± 0.011	0.652TrpGly: 0.652 ± 0.018	0.344TrpHis: 0.344 ± 0.009	0.64TrpIle: 0.64 ± 0.012	0.924TrpLys: 0.924 ± 0.015	1.177TrpLeu: 1.177 ± 0.015	0.307TrpMet: 0.307 ± 0.008	0.716TrpAsn: 0.716 ± 0.012	0.432TrpPro: 0.432 ± 0.009	0.552TrpGln: 0.552 ± 0.01	0.67TrpArg: 0.67 ± 0.012	0.907TrpSer: 0.907 ± 0.015	0.673TrpThr: 0.673 ± 0.013	0.683TrpVal: 0.683 ± 0.012	0.202TrpTrp: 0.202 ± 0.006	0.374TrpTyr: 0.374 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.598TyrAla: 1.598 ± 0.02	0.797TyrCys: 0.797 ± 0.013	1.473TyrAsp: 1.473 ± 0.016	1.832TyrGlu: 1.832 ± 0.02	1.421TyrPhe: 1.421 ± 0.019	1.799TyrGly: 1.799 ± 0.023	0.804TyrHis: 0.804 ± 0.013	1.653TyrIle: 1.653 ± 0.019	1.725TyrLys: 1.725 ± 0.02	2.989TyrLeu: 2.989 ± 0.027	0.693TyrMet: 0.693 ± 0.011	1.32TyrAsn: 1.32 ± 0.017	1.329TyrPro: 1.329 ± 0.017	1.32TyrGln: 1.32 ± 0.016	1.72TyrArg: 1.72 ± 0.019	2.424TyrSer: 2.424 ± 0.024	1.655TyrThr: 1.655 ± 0.02	1.792TyrVal: 1.792 ± 0.022	0.404TyrTrp: 0.404 ± 0.011	1.099TyrTyr: 1.099 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.001	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.028XaaXaa: 0.028 ± 0.005

Statistics based on 12773 proteins (5377037 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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