Amino acid dipepetide frequency for Raphanus sativus cryptic virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.5AlaAla: 6.5 ± 5.058
0.929AlaCys: 0.929 ± 0.637
3.714AlaAsp: 3.714 ± 0.172
5.571AlaGlu: 5.571 ± 1.102
3.714AlaPhe: 3.714 ± 1.531
4.643AlaGly: 4.643 ± 0.465
4.643AlaHis: 4.643 ± 3.613
1.857AlaIle: 1.857 ± 1.273
0.929AlaLys: 0.929 ± 0.637
7.428AlaLeu: 7.428 ± 1.703
3.714AlaMet: 3.714 ± 1.531
1.857AlaAsn: 1.857 ± 1.445
8.357AlaPro: 8.357 ± 5.144
2.786AlaGln: 2.786 ± 0.551
8.357AlaArg: 8.357 ± 1.066
3.714AlaSer: 3.714 ± 1.188
1.857AlaThr: 1.857 ± 1.445
3.714AlaVal: 3.714 ± 1.531
0.0AlaTrp: 0.0 ± 0.0
0.929AlaTyr: 0.929 ± 0.637
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.929CysAsp: 0.929 ± 0.723
0.929CysGlu: 0.929 ± 0.723
0.929CysPhe: 0.929 ± 0.637
2.786CysGly: 2.786 ± 1.91
0.929CysHis: 0.929 ± 0.723
1.857CysIle: 1.857 ± 0.086
0.0CysLys: 0.0 ± 0.0
1.857CysLeu: 1.857 ± 0.086
0.0CysMet: 0.0 ± 0.0
1.857CysAsn: 1.857 ± 0.086
1.857CysPro: 1.857 ± 1.273
1.857CysGln: 1.857 ± 0.086
3.714CysArg: 3.714 ± 2.547
0.929CysSer: 0.929 ± 0.723
2.786CysThr: 2.786 ± 1.91
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.929CysTyr: 0.929 ± 0.637
0.0CysXaa: 0.0 ± 0.0
Asp
3.714AspAla: 3.714 ± 0.172
0.929AspCys: 0.929 ± 0.637
2.786AspAsp: 2.786 ± 0.551
2.786AspGlu: 2.786 ± 0.551
1.857AspPhe: 1.857 ± 1.273
1.857AspGly: 1.857 ± 1.445
2.786AspHis: 2.786 ± 1.91
3.714AspIle: 3.714 ± 0.172
0.929AspLys: 0.929 ± 0.723
2.786AspLeu: 2.786 ± 0.808
0.929AspMet: 0.929 ± 0.637
3.714AspAsn: 3.714 ± 0.172
4.643AspPro: 4.643 ± 0.465
0.0AspGln: 0.0 ± 0.0
1.857AspArg: 1.857 ± 0.086
5.571AspSer: 5.571 ± 1.617
5.571AspThr: 5.571 ± 3.82
3.714AspVal: 3.714 ± 1.188
1.857AspTrp: 1.857 ± 1.273
0.929AspTyr: 0.929 ± 0.637
0.0AspXaa: 0.0 ± 0.0
Glu
5.571GluAla: 5.571 ± 1.102
0.0GluCys: 0.0 ± 0.0
2.786GluAsp: 2.786 ± 0.808
0.929GluGlu: 0.929 ± 0.637
2.786GluPhe: 2.786 ± 0.551
0.0GluGly: 0.0 ± 0.0
0.0GluHis: 0.0 ± 0.0
0.0GluIle: 0.0 ± 0.0
0.0GluLys: 0.0 ± 0.0
5.571GluLeu: 5.571 ± 0.257
0.929GluMet: 0.929 ± 0.723
2.786GluAsn: 2.786 ± 0.808
3.714GluPro: 3.714 ± 0.172
2.786GluGln: 2.786 ± 0.808
1.857GluArg: 1.857 ± 0.086
0.929GluSer: 0.929 ± 0.723
5.571GluThr: 5.571 ± 0.257
1.857GluVal: 1.857 ± 1.273
0.929GluTrp: 0.929 ± 0.637
1.857GluTyr: 1.857 ± 0.086
0.0GluXaa: 0.0 ± 0.0
Phe
5.571PheAla: 5.571 ± 1.102
3.714PheCys: 3.714 ± 2.547
5.571PheAsp: 5.571 ± 1.102
1.857PheGlu: 1.857 ± 1.445
2.786PhePhe: 2.786 ± 0.551
3.714PheGly: 3.714 ± 0.172
1.857PheHis: 1.857 ± 0.086
1.857PheIle: 1.857 ± 0.086
0.0PheLys: 0.0 ± 0.0
5.571PheLeu: 5.571 ± 0.257
0.929PheMet: 0.929 ± 0.637
2.786PheAsn: 2.786 ± 0.551
2.786PhePro: 2.786 ± 0.808
0.929PheGln: 0.929 ± 0.637
2.786PheArg: 2.786 ± 0.551
5.571PheSer: 5.571 ± 0.257
5.571PheThr: 5.571 ± 2.461
0.929PheVal: 0.929 ± 0.723
2.786PheTrp: 2.786 ± 0.551
2.786PheTyr: 2.786 ± 0.551
0.0PheXaa: 0.0 ± 0.0
Gly
2.786GlyAla: 2.786 ± 0.551
0.0GlyCys: 0.0 ± 0.0
1.857GlyAsp: 1.857 ± 1.273
0.929GlyGlu: 0.929 ± 0.637
2.786GlyPhe: 2.786 ± 1.91
0.929GlyGly: 0.929 ± 0.637
0.929GlyHis: 0.929 ± 0.723
4.643GlyIle: 4.643 ± 1.824
0.929GlyLys: 0.929 ± 0.637
5.571GlyLeu: 5.571 ± 1.102
0.929GlyMet: 0.929 ± 0.637
1.857GlyAsn: 1.857 ± 0.086
1.857GlyPro: 1.857 ± 1.445
0.929GlyGln: 0.929 ± 0.723
0.0GlyArg: 0.0 ± 0.0
6.5GlySer: 6.5 ± 2.339
2.786GlyThr: 2.786 ± 0.808
1.857GlyVal: 1.857 ± 0.086
2.786GlyTrp: 2.786 ± 0.808
2.786GlyTyr: 2.786 ± 0.551
0.0GlyXaa: 0.0 ± 0.0
His
0.929HisAla: 0.929 ± 0.637
0.0HisCys: 0.0 ± 0.0
0.929HisAsp: 0.929 ± 0.637
0.929HisGlu: 0.929 ± 0.637
2.786HisPhe: 2.786 ± 1.91
3.714HisGly: 3.714 ± 0.172
3.714HisHis: 3.714 ± 0.172
4.643HisIle: 4.643 ± 0.465
0.0HisLys: 0.0 ± 0.0
2.786HisLeu: 2.786 ± 2.168
0.929HisMet: 0.929 ± 0.723
0.929HisAsn: 0.929 ± 0.637
4.643HisPro: 4.643 ± 0.894
0.929HisGln: 0.929 ± 0.723
1.857HisArg: 1.857 ± 0.086
1.857HisSer: 1.857 ± 1.445
0.0HisThr: 0.0 ± 0.0
0.929HisVal: 0.929 ± 0.637
0.929HisTrp: 0.929 ± 0.637
0.929HisTyr: 0.929 ± 0.637
0.0HisXaa: 0.0 ± 0.0
Ile
1.857IleAla: 1.857 ± 1.445
4.643IleCys: 4.643 ± 0.894
0.929IleAsp: 0.929 ± 0.637
1.857IleGlu: 1.857 ± 0.086
6.5IlePhe: 6.5 ± 1.738
2.786IleGly: 2.786 ± 1.91
1.857IleHis: 1.857 ± 1.273
0.929IleIle: 0.929 ± 0.637
0.929IleLys: 0.929 ± 0.637
0.929IleLeu: 0.929 ± 0.637
1.857IleMet: 1.857 ± 0.394
1.857IleAsn: 1.857 ± 0.086
5.571IlePro: 5.571 ± 1.617
0.0IleGln: 0.0 ± 0.0
2.786IleArg: 2.786 ± 0.551
6.5IleSer: 6.5 ± 2.339
1.857IleThr: 1.857 ± 0.086
0.0IleVal: 0.0 ± 0.0
0.0IleTrp: 0.0 ± 0.0
3.714IleTyr: 3.714 ± 0.172
0.0IleXaa: 0.0 ± 0.0
Lys
0.929LysAla: 0.929 ± 0.723
0.929LysCys: 0.929 ± 0.637
2.786LysAsp: 2.786 ± 1.91
0.0LysGlu: 0.0 ± 0.0
0.0LysPhe: 0.0 ± 0.0
0.929LysGly: 0.929 ± 0.723
0.929LysHis: 0.929 ± 0.637
2.786LysIle: 2.786 ± 1.91
3.714LysLys: 3.714 ± 1.188
0.929LysLeu: 0.929 ± 0.637
1.857LysMet: 1.857 ± 1.129
0.0LysAsn: 0.0 ± 0.0
0.929LysPro: 0.929 ± 0.637
0.929LysGln: 0.929 ± 0.637
1.857LysArg: 1.857 ± 1.273
4.643LysSer: 4.643 ± 3.184
0.0LysThr: 0.0 ± 0.0
2.786LysVal: 2.786 ± 1.91
0.929LysTrp: 0.929 ± 0.637
1.857LysTyr: 1.857 ± 0.086
0.0LysXaa: 0.0 ± 0.0
Leu
3.714LeuAla: 3.714 ± 1.531
0.929LeuCys: 0.929 ± 0.723
5.571LeuAsp: 5.571 ± 2.461
4.643LeuGlu: 4.643 ± 0.465
6.5LeuPhe: 6.5 ± 2.339
4.643LeuGly: 4.643 ± 3.184
5.571LeuHis: 5.571 ± 2.461
4.643LeuIle: 4.643 ± 2.253
4.643LeuLys: 4.643 ± 1.824
9.285LeuLeu: 9.285 ± 0.93
2.786LeuMet: 2.786 ± 0.808
7.428LeuAsn: 7.428 ± 0.343
4.643LeuPro: 4.643 ± 3.613
5.571LeuGln: 5.571 ± 0.257
2.786LeuArg: 2.786 ± 0.808
5.571LeuSer: 5.571 ± 0.257
1.857LeuThr: 1.857 ± 1.445
3.714LeuVal: 3.714 ± 0.172
2.786LeuTrp: 2.786 ± 0.551
3.714LeuTyr: 3.714 ± 0.172
0.0LeuXaa: 0.0 ± 0.0
Met
1.857MetAla: 1.857 ± 0.086
0.0MetCys: 0.0 ± 0.0
1.857MetAsp: 1.857 ± 1.445
0.0MetGlu: 0.0 ± 0.0
1.857MetPhe: 1.857 ± 0.086
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.929MetIle: 0.929 ± 0.723
0.929MetLys: 0.929 ± 0.723
1.857MetLeu: 1.857 ± 0.086
0.929MetMet: 0.929 ± 0.723
0.929MetAsn: 0.929 ± 0.723
0.929MetPro: 0.929 ± 0.637
0.0MetGln: 0.0 ± 0.0
2.786MetArg: 2.786 ± 0.551
2.786MetSer: 2.786 ± 0.551
0.929MetThr: 0.929 ± 0.723
2.786MetVal: 2.786 ± 0.808
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
4.643AsnAla: 4.643 ± 0.894
4.643AsnCys: 4.643 ± 0.465
8.357AsnAsp: 8.357 ± 1.066
2.786AsnGlu: 2.786 ± 0.808
1.857AsnPhe: 1.857 ± 1.445
5.571AsnGly: 5.571 ± 0.257
1.857AsnHis: 1.857 ± 0.086
0.929AsnIle: 0.929 ± 0.723
1.857AsnLys: 1.857 ± 1.445
7.428AsnLeu: 7.428 ± 1.703
0.0AsnMet: 0.0 ± 0.0
0.929AsnAsn: 0.929 ± 0.723
3.714AsnPro: 3.714 ± 1.531
0.929AsnGln: 0.929 ± 0.637
0.929AsnArg: 0.929 ± 0.723
3.714AsnSer: 3.714 ± 1.188
1.857AsnThr: 1.857 ± 1.445
0.929AsnVal: 0.929 ± 0.723
2.786AsnTrp: 2.786 ± 0.551
2.786AsnTyr: 2.786 ± 1.91
0.0AsnXaa: 0.0 ± 0.0
Pro
9.285ProAla: 9.285 ± 4.507
0.929ProCys: 0.929 ± 0.637
0.929ProAsp: 0.929 ± 0.723
2.786ProGlu: 2.786 ± 2.168
3.714ProPhe: 3.714 ± 0.172
4.643ProGly: 4.643 ± 3.613
0.929ProHis: 0.929 ± 0.723
3.714ProIle: 3.714 ± 1.188
4.643ProLys: 4.643 ± 3.184
7.428ProLeu: 7.428 ± 0.343
0.0ProMet: 0.0 ± 0.0
12.071ProAsn: 12.071 ± 6.674
6.5ProPro: 6.5 ± 3.698
1.857ProGln: 1.857 ± 0.086
2.786ProArg: 2.786 ± 1.91
6.5ProSer: 6.5 ± 0.379
4.643ProThr: 4.643 ± 0.894
4.643ProVal: 4.643 ± 0.894
0.929ProTrp: 0.929 ± 0.637
1.857ProTyr: 1.857 ± 1.445
0.0ProXaa: 0.0 ± 0.0
Gln
2.786GlnAla: 2.786 ± 0.551
0.0GlnCys: 0.0 ± 0.0
1.857GlnAsp: 1.857 ± 0.086
0.929GlnGlu: 0.929 ± 0.723
2.786GlnPhe: 2.786 ± 0.551
0.0GlnGly: 0.0 ± 0.0
0.0GlnHis: 0.0 ± 0.0
0.929GlnIle: 0.929 ± 0.723
0.0GlnLys: 0.0 ± 0.0
6.5GlnLeu: 6.5 ± 1.738
0.0GlnMet: 0.0 ± 0.0
0.929GlnAsn: 0.929 ± 0.637
0.0GlnPro: 0.0 ± 0.0
1.857GlnGln: 1.857 ± 1.273
1.857GlnArg: 1.857 ± 0.086
0.929GlnSer: 0.929 ± 0.637
1.857GlnThr: 1.857 ± 1.445
4.643GlnVal: 4.643 ± 0.894
1.857GlnTrp: 1.857 ± 0.086
0.929GlnTyr: 0.929 ± 0.723
0.0GlnXaa: 0.0 ± 0.0
Arg
3.714ArgAla: 3.714 ± 1.531
0.0ArgCys: 0.0 ± 0.0
3.714ArgAsp: 3.714 ± 2.547
1.857ArgGlu: 1.857 ± 1.445
3.714ArgPhe: 3.714 ± 1.188
0.0ArgGly: 0.0 ± 0.0
1.857ArgHis: 1.857 ± 0.086
1.857ArgIle: 1.857 ± 0.086
0.929ArgLys: 0.929 ± 0.637
5.571ArgLeu: 5.571 ± 1.102
0.929ArgMet: 0.929 ± 0.637
1.857ArgAsn: 1.857 ± 0.086
7.428ArgPro: 7.428 ± 0.343
1.857ArgGln: 1.857 ± 1.445
5.571ArgArg: 5.571 ± 1.102
5.571ArgSer: 5.571 ± 1.102
4.643ArgThr: 4.643 ± 0.465
0.929ArgVal: 0.929 ± 0.637
0.929ArgTrp: 0.929 ± 0.637
1.857ArgTyr: 1.857 ± 1.273
0.0ArgXaa: 0.0 ± 0.0
Ser
12.071SerAla: 12.071 ± 5.315
0.929SerCys: 0.929 ± 0.637
1.857SerAsp: 1.857 ± 0.086
7.428SerGlu: 7.428 ± 0.343
6.5SerPhe: 6.5 ± 0.379
4.643SerGly: 4.643 ± 0.465
1.857SerHis: 1.857 ± 0.086
3.714SerIle: 3.714 ± 0.172
4.643SerLys: 4.643 ± 3.184
6.5SerLeu: 6.5 ± 0.98
2.786SerMet: 2.786 ± 0.808
3.714SerAsn: 3.714 ± 1.188
2.786SerPro: 2.786 ± 0.808
2.786SerGln: 2.786 ± 0.808
1.857SerArg: 1.857 ± 0.086
9.285SerSer: 9.285 ± 0.429
4.643SerThr: 4.643 ± 0.465
0.0SerVal: 0.0 ± 0.0
0.929SerTrp: 0.929 ± 0.723
5.571SerTyr: 5.571 ± 1.617
0.0SerXaa: 0.0 ± 0.0
Thr
5.571ThrAla: 5.571 ± 1.617
2.786ThrCys: 2.786 ± 0.551
3.714ThrAsp: 3.714 ± 1.188
1.857ThrGlu: 1.857 ± 1.273
1.857ThrPhe: 1.857 ± 1.445
1.857ThrGly: 1.857 ± 1.273
1.857ThrHis: 1.857 ± 1.273
3.714ThrIle: 3.714 ± 0.172
0.0ThrLys: 0.0 ± 0.0
4.643ThrLeu: 4.643 ± 0.465
0.0ThrMet: 0.0 ± 0.0
4.643ThrAsn: 4.643 ± 0.894
6.5ThrPro: 6.5 ± 0.98
0.929ThrGln: 0.929 ± 0.637
1.857ThrArg: 1.857 ± 0.086
4.643ThrSer: 4.643 ± 2.253
3.714ThrThr: 3.714 ± 2.547
4.643ThrVal: 4.643 ± 0.465
0.929ThrTrp: 0.929 ± 0.723
2.786ThrTyr: 2.786 ± 1.91
0.0ThrXaa: 0.0 ± 0.0
Val
0.929ValAla: 0.929 ± 0.723
0.0ValCys: 0.0 ± 0.0
0.929ValAsp: 0.929 ± 0.723
1.857ValGlu: 1.857 ± 1.273
0.929ValPhe: 0.929 ± 0.637
0.0ValGly: 0.0 ± 0.0
0.929ValHis: 0.929 ± 0.637
1.857ValIle: 1.857 ± 0.086
2.786ValLys: 2.786 ± 1.91
4.643ValLeu: 4.643 ± 0.465
0.929ValMet: 0.929 ± 0.723
2.786ValAsn: 2.786 ± 2.168
4.643ValPro: 4.643 ± 2.253
1.857ValGln: 1.857 ± 0.086
4.643ValArg: 4.643 ± 0.465
1.857ValSer: 1.857 ± 1.445
4.643ValThr: 4.643 ± 1.824
1.857ValVal: 1.857 ± 0.086
0.0ValTrp: 0.0 ± 0.0
2.786ValTyr: 2.786 ± 0.551
0.0ValXaa: 0.0 ± 0.0
Trp
0.929TrpAla: 0.929 ± 0.637
0.0TrpCys: 0.0 ± 0.0
0.929TrpAsp: 0.929 ± 0.637
0.0TrpGlu: 0.0 ± 0.0
1.857TrpPhe: 1.857 ± 0.086
0.0TrpGly: 0.0 ± 0.0
0.929TrpHis: 0.929 ± 0.723
0.929TrpIle: 0.929 ± 0.637
0.929TrpLys: 0.929 ± 0.637
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
3.714TrpAsn: 3.714 ± 1.188
2.786TrpPro: 2.786 ± 1.91
0.929TrpGln: 0.929 ± 0.637
0.929TrpArg: 0.929 ± 0.723
1.857TrpSer: 1.857 ± 0.086
2.786TrpThr: 2.786 ± 2.168
0.929TrpVal: 0.929 ± 0.723
0.0TrpTrp: 0.0 ± 0.0
2.786TrpTyr: 2.786 ± 1.91
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.857TyrAla: 1.857 ± 1.273
2.786TyrCys: 2.786 ± 0.551
0.929TyrAsp: 0.929 ± 0.637
0.929TyrGlu: 0.929 ± 0.637
4.643TyrPhe: 4.643 ± 3.184
0.929TyrGly: 0.929 ± 0.723
0.929TyrHis: 0.929 ± 0.723
2.786TyrIle: 2.786 ± 0.808
0.929TyrLys: 0.929 ± 0.637
3.714TyrLeu: 3.714 ± 1.531
0.0TyrMet: 0.0 ± 0.0
1.857TyrAsn: 1.857 ± 1.273
6.5TyrPro: 6.5 ± 0.379
0.929TyrGln: 0.929 ± 0.637
3.714TyrArg: 3.714 ± 1.188
5.571TyrSer: 5.571 ± 0.257
0.929TyrThr: 0.929 ± 0.637
0.0TyrVal: 0.0 ± 0.0
1.857TyrTrp: 1.857 ± 0.086
5.571TyrTyr: 5.571 ± 0.257
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1078 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski