Vicugna pacos (Alpaca) (Lama pacos)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Laurasiatheria;

Average proteome isoelectric point is 6.69

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 36880 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A6J3BDL2|A0A6J3BDL2_VICPA Isoform of A0A6J3BBS2 CTD small phosphatase-like protein isoform X5 OS=Vicugna pacos OX=30538 GN=CTDSPL PE=4 SV=1
MM1 pKa = 7.36EE2 pKa = 5.31AVSLSPYY9 pKa = 10.69VLGLLLLPLLAVLLMALCVRR29 pKa = 11.84CRR31 pKa = 11.84EE32 pKa = 4.25LPGSYY37 pKa = 8.66DD38 pKa = 3.31TAASDD43 pKa = 3.84SLTPSSIVIKK53 pKa = 10.35RR54 pKa = 11.84PPTLAPWPPATSYY67 pKa = 11.11PPVTSYY73 pKa = 11.3PPLNQPDD80 pKa = 4.81LLPIPRR86 pKa = 11.84SPQPPGGSHH95 pKa = 6.82RR96 pKa = 11.84MPSSRR101 pKa = 11.84QASDD105 pKa = 3.11GANSVASYY113 pKa = 10.76EE114 pKa = 4.13NEE116 pKa = 3.86EE117 pKa = 4.29PVCEE121 pKa = 5.65DD122 pKa = 3.23EE123 pKa = 7.0DD124 pKa = 4.15EE125 pKa = 5.92DD126 pKa = 4.66EE127 pKa = 6.11DD128 pKa = 4.81EE129 pKa = 4.41EE130 pKa = 5.69DD131 pKa = 3.77YY132 pKa = 11.56HH133 pKa = 8.4NEE135 pKa = 4.02GYY137 pKa = 10.83LVVLPDD143 pKa = 3.85SVPATGTTVPPAPVSNNPGPRR164 pKa = 11.84DD165 pKa = 3.34SAFSMEE171 pKa = 4.23SGEE174 pKa = 4.99DD175 pKa = 3.63YY176 pKa = 11.66VNVPEE181 pKa = 4.68SEE183 pKa = 4.29EE184 pKa = 4.1SADD187 pKa = 3.58ASLDD191 pKa = 3.44GSRR194 pKa = 11.84EE195 pKa = 3.99YY196 pKa = 11.72VNVSQEE202 pKa = 4.06LQPVAGTKK210 pKa = 9.68PATPGSRR217 pKa = 11.84EE218 pKa = 4.08VEE220 pKa = 4.17DD221 pKa = 4.96EE222 pKa = 4.04EE223 pKa = 6.11APDD226 pKa = 4.29YY227 pKa = 11.55EE228 pKa = 4.24NLQPNN233 pKa = 3.81

Molecular weight: 24.94 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A6J0AI98|A0A6J0AI98_VICPA forkhead box protein I3 OS=Vicugna pacos OX=30538 GN=FOXI3 PE=4 SV=1
MM1 pKa = 7.52SPLKK5 pKa = 9.95TFRR8 pKa = 11.84TRR10 pKa = 11.84RR11 pKa = 11.84FLVKK15 pKa = 9.92KK16 pKa = 9.95QKK18 pKa = 9.18QNRR21 pKa = 11.84PTPQWVHH28 pKa = 4.65MKK30 pKa = 8.71TRR32 pKa = 11.84SKK34 pKa = 10.24IRR36 pKa = 11.84HH37 pKa = 4.55NSKK40 pKa = 8.85RR41 pKa = 11.84RR42 pKa = 11.84RR43 pKa = 11.84WRR45 pKa = 11.84RR46 pKa = 11.84TKK48 pKa = 9.9WGLL51 pKa = 3.16

Molecular weight: 6.53 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

19465

17415

36880

24174655

31

34501

655.5

73.0

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.98 ± 0.013

2.081 ± 0.009

4.898 ± 0.009

7.289 ± 0.018

3.451 ± 0.01

6.377 ± 0.017

2.574 ± 0.006

4.197 ± 0.011

5.855 ± 0.02

9.863 ± 0.017

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.12 ± 0.005

3.539 ± 0.01

6.376 ± 0.022

4.945 ± 0.012

5.739 ± 0.013

8.579 ± 0.018

5.372 ± 0.011

6.012 ± 0.013

1.155 ± 0.004

2.566 ± 0.011
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski