Amino acid dipepetide frequency for Asparagus virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.26AlaAla: 6.26 ± 1.509
0.782AlaCys: 0.782 ± 1.037
3.912AlaAsp: 3.912 ± 1.068
2.739AlaGlu: 2.739 ± 1.426
1.956AlaPhe: 1.956 ± 0.789
3.912AlaGly: 3.912 ± 1.372
1.174AlaHis: 1.174 ± 0.455
5.086AlaIle: 5.086 ± 0.704
5.086AlaLys: 5.086 ± 0.968
5.869AlaLeu: 5.869 ± 0.423
1.174AlaMet: 1.174 ± 0.364
2.739AlaAsn: 2.739 ± 0.975
5.086AlaPro: 5.086 ± 3.598
1.565AlaGln: 1.565 ± 1.022
5.477AlaArg: 5.477 ± 2.416
3.912AlaSer: 3.912 ± 1.46
5.086AlaThr: 5.086 ± 2.013
5.086AlaVal: 5.086 ± 0.805
1.565AlaTrp: 1.565 ± 0.446
2.739AlaTyr: 2.739 ± 0.689
0.0AlaXaa: 0.0 ± 0.0
Cys
1.956CysAla: 1.956 ± 0.76
0.391CysCys: 0.391 ± 0.268
1.956CysAsp: 1.956 ± 0.409
1.565CysGlu: 1.565 ± 0.87
1.565CysPhe: 1.565 ± 0.382
1.956CysGly: 1.956 ± 0.76
0.0CysHis: 0.0 ± 0.0
0.391CysIle: 0.391 ± 0.268
0.391CysLys: 0.391 ± 0.518
1.565CysLeu: 1.565 ± 0.87
0.0CysMet: 0.0 ± 0.0
1.174CysAsn: 1.174 ± 0.458
0.782CysPro: 0.782 ± 0.536
0.391CysGln: 0.391 ± 0.328
0.782CysArg: 0.782 ± 0.482
2.739CysSer: 2.739 ± 0.924
0.391CysThr: 0.391 ± 0.268
0.782CysVal: 0.782 ± 0.482
0.391CysTrp: 0.391 ± 0.328
0.782CysTyr: 0.782 ± 0.656
0.0CysXaa: 0.0 ± 0.0
Asp
8.998AspAla: 8.998 ± 0.743
0.782AspCys: 0.782 ± 0.656
8.216AspAsp: 8.216 ± 3.658
3.912AspGlu: 3.912 ± 1.15
3.13AspPhe: 3.13 ± 0.873
5.086AspGly: 5.086 ± 0.715
1.174AspHis: 1.174 ± 0.583
2.739AspIle: 2.739 ± 1.426
3.13AspLys: 3.13 ± 1.419
6.26AspLeu: 6.26 ± 1.438
0.0AspMet: 0.0 ± 0.0
1.956AspAsn: 1.956 ± 0.551
1.565AspPro: 1.565 ± 0.687
1.174AspGln: 1.174 ± 0.804
3.521AspArg: 3.521 ± 0.801
3.13AspSer: 3.13 ± 0.782
3.912AspThr: 3.912 ± 1.196
6.651AspVal: 6.651 ± 1.936
0.391AspTrp: 0.391 ± 0.5
2.739AspTyr: 2.739 ± 1.134
0.0AspXaa: 0.0 ± 0.0
Glu
5.086GluAla: 5.086 ± 1.468
2.739GluCys: 2.739 ± 0.924
4.304GluAsp: 4.304 ± 1.063
3.912GluGlu: 3.912 ± 0.879
1.956GluPhe: 1.956 ± 1.195
1.565GluGly: 1.565 ± 0.446
0.391GluHis: 0.391 ± 0.328
3.13GluIle: 3.13 ± 1.742
3.912GluLys: 3.912 ± 0.616
4.695GluLeu: 4.695 ± 0.559
3.13GluMet: 3.13 ± 0.816
1.174GluAsn: 1.174 ± 0.583
1.565GluPro: 1.565 ± 0.87
2.347GluGln: 2.347 ± 0.432
2.739GluArg: 2.739 ± 0.61
2.347GluSer: 2.347 ± 0.534
3.912GluThr: 3.912 ± 0.954
5.086GluVal: 5.086 ± 1.72
0.0GluTrp: 0.0 ± 0.0
0.782GluTyr: 0.782 ± 0.292
0.0GluXaa: 0.0 ± 0.0
Phe
2.739PheAla: 2.739 ± 0.93
0.391PheCys: 0.391 ± 0.268
2.739PheAsp: 2.739 ± 0.949
3.13PheGlu: 3.13 ± 1.358
1.174PhePhe: 1.174 ± 0.404
1.565PheGly: 1.565 ± 0.702
1.565PheHis: 1.565 ± 0.584
3.13PheIle: 3.13 ± 0.717
1.956PheLys: 1.956 ± 1.189
3.521PheLeu: 3.521 ± 1.346
0.782PheMet: 0.782 ± 0.536
1.174PheAsn: 1.174 ± 0.56
4.695PhePro: 4.695 ± 1.94
1.956PheGln: 1.956 ± 0.716
3.521PheArg: 3.521 ± 1.14
3.13PheSer: 3.13 ± 1.007
3.521PheThr: 3.521 ± 1.627
3.912PheVal: 3.912 ± 0.935
0.0PheTrp: 0.0 ± 0.0
1.956PheTyr: 1.956 ± 0.467
0.0PheXaa: 0.0 ± 0.0
Gly
2.739GlyAla: 2.739 ± 1.202
1.565GlyCys: 1.565 ± 0.87
3.521GlyAsp: 3.521 ± 0.768
2.347GlyGlu: 2.347 ± 0.539
3.521GlyPhe: 3.521 ± 1.728
1.565GlyGly: 1.565 ± 0.632
0.391GlyHis: 0.391 ± 0.328
1.956GlyIle: 1.956 ± 0.716
4.304GlyLys: 4.304 ± 0.563
3.912GlyLeu: 3.912 ± 1.684
1.174GlyMet: 1.174 ± 0.804
2.739GlyAsn: 2.739 ± 0.619
1.174GlyPro: 1.174 ± 0.687
1.174GlyGln: 1.174 ± 0.848
4.304GlyArg: 4.304 ± 1.279
5.477GlySer: 5.477 ± 1.181
1.565GlyThr: 1.565 ± 1.116
4.304GlyVal: 4.304 ± 1.131
1.565GlyTrp: 1.565 ± 0.702
1.565GlyTyr: 1.565 ± 1.207
0.0GlyXaa: 0.0 ± 0.0
His
1.565HisAla: 1.565 ± 0.687
0.782HisCys: 0.782 ± 0.536
0.391HisAsp: 0.391 ± 0.61
2.347HisGlu: 2.347 ± 0.507
0.782HisPhe: 0.782 ± 0.459
0.0HisGly: 0.0 ± 0.0
0.782HisHis: 0.782 ± 0.656
1.956HisIle: 1.956 ± 0.409
1.956HisLys: 1.956 ± 0.716
1.956HisLeu: 1.956 ± 0.76
0.391HisMet: 0.391 ± 0.328
1.174HisAsn: 1.174 ± 0.455
0.782HisPro: 0.782 ± 0.885
0.782HisGln: 0.782 ± 0.656
1.174HisArg: 1.174 ± 0.56
1.956HisSer: 1.956 ± 1.34
1.956HisThr: 1.956 ± 0.573
0.391HisVal: 0.391 ± 0.328
0.391HisTrp: 0.391 ± 0.328
1.565HisTyr: 1.565 ± 0.584
0.0HisXaa: 0.0 ± 0.0
Ile
5.477IleAla: 5.477 ± 1.6
0.782IleCys: 0.782 ± 0.656
1.956IleAsp: 1.956 ± 0.844
3.13IleGlu: 3.13 ± 0.697
1.956IlePhe: 1.956 ± 1.167
3.13IleGly: 3.13 ± 0.546
1.956IleHis: 1.956 ± 0.807
2.739IleIle: 2.739 ± 1.16
3.912IleLys: 3.912 ± 0.525
2.347IleLeu: 2.347 ± 0.534
1.174IleMet: 1.174 ± 0.455
2.739IleAsn: 2.739 ± 1.486
5.477IlePro: 5.477 ± 1.533
1.956IleGln: 1.956 ± 0.624
2.739IleArg: 2.739 ± 0.554
4.695IleSer: 4.695 ± 1.576
3.912IleThr: 3.912 ± 0.631
2.347IleVal: 2.347 ± 0.876
0.0IleTrp: 0.0 ± 0.0
1.956IleTyr: 1.956 ± 0.716
0.0IleXaa: 0.0 ± 0.0
Lys
2.739LysAla: 2.739 ± 1.338
1.565LysCys: 1.565 ± 0.946
2.739LysAsp: 2.739 ± 0.689
2.739LysGlu: 2.739 ± 1.019
5.477LysPhe: 5.477 ± 1.794
2.739LysGly: 2.739 ± 0.928
0.391LysHis: 0.391 ± 0.268
4.304LysIle: 4.304 ± 1.174
4.695LysLys: 4.695 ± 1.206
2.739LysLeu: 2.739 ± 0.716
2.739LysMet: 2.739 ± 1.19
3.521LysAsn: 3.521 ± 1.29
5.086LysPro: 5.086 ± 1.218
2.347LysGln: 2.347 ± 0.777
1.956LysArg: 1.956 ± 1.043
5.086LysSer: 5.086 ± 0.715
5.869LysThr: 5.869 ± 2.177
3.521LysVal: 3.521 ± 0.888
1.565LysTrp: 1.565 ± 0.87
2.739LysTyr: 2.739 ± 0.619
0.0LysXaa: 0.0 ± 0.0
Leu
5.477LeuAla: 5.477 ± 1.014
3.13LeuCys: 3.13 ± 2.177
4.695LeuAsp: 4.695 ± 1.68
5.086LeuGlu: 5.086 ± 1.382
3.912LeuPhe: 3.912 ± 1.018
3.521LeuGly: 3.521 ± 1.319
1.174LeuHis: 1.174 ± 0.813
3.912LeuIle: 3.912 ± 1.585
7.433LeuLys: 7.433 ± 1.593
6.651LeuLeu: 6.651 ± 1.543
1.956LeuMet: 1.956 ± 0.84
2.739LeuAsn: 2.739 ± 1.034
5.477LeuPro: 5.477 ± 1.483
1.956LeuGln: 1.956 ± 1.189
3.912LeuArg: 3.912 ± 1.801
7.433LeuSer: 7.433 ± 1.71
3.521LeuThr: 3.521 ± 1.477
7.042LeuVal: 7.042 ± 1.243
0.391LeuTrp: 0.391 ± 0.518
2.347LeuTyr: 2.347 ± 0.777
0.0LeuXaa: 0.0 ± 0.0
Met
2.347MetAla: 2.347 ± 1.154
0.391MetCys: 0.391 ± 0.268
3.13MetAsp: 3.13 ± 0.927
0.782MetGlu: 0.782 ± 0.482
0.391MetPhe: 0.391 ± 0.518
1.174MetGly: 1.174 ± 0.455
0.391MetHis: 0.391 ± 0.328
1.174MetIle: 1.174 ± 0.785
1.174MetLys: 1.174 ± 0.455
1.956MetLeu: 1.956 ± 0.576
1.174MetMet: 1.174 ± 0.562
0.782MetAsn: 0.782 ± 0.544
1.565MetPro: 1.565 ± 0.575
1.174MetGln: 1.174 ± 0.455
1.565MetArg: 1.565 ± 1.472
1.565MetSer: 1.565 ± 0.446
1.565MetThr: 1.565 ± 0.687
1.956MetVal: 1.956 ± 0.573
1.174MetTrp: 1.174 ± 0.687
0.782MetTyr: 0.782 ± 0.656
0.0MetXaa: 0.0 ± 0.0
Asn
2.739AsnAla: 2.739 ± 1.794
0.391AsnCys: 0.391 ± 0.518
1.565AsnAsp: 1.565 ± 0.584
1.565AsnGlu: 1.565 ± 1.223
2.347AsnPhe: 2.347 ± 1.136
1.956AsnGly: 1.956 ± 1.061
1.174AsnHis: 1.174 ± 0.455
1.956AsnIle: 1.956 ± 0.409
2.347AsnLys: 2.347 ± 1.006
2.347AsnLeu: 2.347 ± 1.409
0.391AsnMet: 0.391 ± 0.328
0.782AsnAsn: 0.782 ± 0.885
2.347AsnPro: 2.347 ± 0.732
1.565AsnGln: 1.565 ± 0.568
1.565AsnArg: 1.565 ± 0.584
3.13AsnSer: 3.13 ± 0.887
3.13AsnThr: 3.13 ± 0.853
3.13AsnVal: 3.13 ± 1.538
0.782AsnTrp: 0.782 ± 0.558
1.956AsnTyr: 1.956 ± 0.84
0.0AsnXaa: 0.0 ± 0.0
Pro
2.739ProAla: 2.739 ± 1.23
0.0ProCys: 0.0 ± 0.0
3.521ProAsp: 3.521 ± 1.615
3.521ProGlu: 3.521 ± 0.706
1.174ProPhe: 1.174 ± 0.56
3.521ProGly: 3.521 ± 0.902
1.565ProHis: 1.565 ± 0.498
2.347ProIle: 2.347 ± 1.135
2.347ProLys: 2.347 ± 1.493
5.086ProLeu: 5.086 ± 1.921
3.521ProMet: 3.521 ± 1.002
3.521ProAsn: 3.521 ± 1.496
3.521ProPro: 3.521 ± 2.047
1.565ProGln: 1.565 ± 0.446
3.912ProArg: 3.912 ± 0.99
3.521ProSer: 3.521 ± 0.525
3.13ProThr: 3.13 ± 3.715
3.13ProVal: 3.13 ± 1.386
0.782ProTrp: 0.782 ± 0.459
0.391ProTyr: 0.391 ± 0.268
0.0ProXaa: 0.0 ± 0.0
Gln
2.347GlnAla: 2.347 ± 1.136
1.174GlnCys: 1.174 ± 0.583
0.782GlnAsp: 0.782 ± 0.656
1.174GlnGlu: 1.174 ± 0.56
1.174GlnPhe: 1.174 ± 0.404
1.565GlnGly: 1.565 ± 0.568
0.391GlnHis: 0.391 ± 0.268
1.956GlnIle: 1.956 ± 0.53
0.0GlnLys: 0.0 ± 0.0
1.956GlnLeu: 1.956 ± 0.789
0.391GlnMet: 0.391 ± 0.487
0.391GlnAsn: 0.391 ± 0.268
2.739GlnPro: 2.739 ± 1.311
0.391GlnGln: 0.391 ± 0.61
1.565GlnArg: 1.565 ± 0.575
3.521GlnSer: 3.521 ± 1.14
2.347GlnThr: 2.347 ± 0.732
1.565GlnVal: 1.565 ± 0.789
0.782GlnTrp: 0.782 ± 1.22
1.956GlnTyr: 1.956 ± 0.716
0.0GlnXaa: 0.0 ± 0.0
Arg
1.956ArgAla: 1.956 ± 1.018
0.391ArgCys: 0.391 ± 0.268
4.695ArgAsp: 4.695 ± 1.541
3.912ArgGlu: 3.912 ± 1.107
2.347ArgPhe: 2.347 ± 0.876
3.13ArgGly: 3.13 ± 0.893
1.565ArgHis: 1.565 ± 1.072
3.13ArgIle: 3.13 ± 1.039
2.347ArgLys: 2.347 ± 0.534
6.26ArgLeu: 6.26 ± 1.096
1.174ArgMet: 1.174 ± 0.364
3.13ArgAsn: 3.13 ± 1.131
1.174ArgPro: 1.174 ± 0.56
2.739ArgGln: 2.739 ± 1.697
6.26ArgArg: 6.26 ± 0.7
3.912ArgSer: 3.912 ± 2.454
2.347ArgThr: 2.347 ± 0.777
6.651ArgVal: 6.651 ± 0.676
1.174ArgTrp: 1.174 ± 0.458
1.565ArgTyr: 1.565 ± 0.382
0.0ArgXaa: 0.0 ± 0.0
Ser
3.13SerAla: 3.13 ± 0.497
1.565SerCys: 1.565 ± 0.687
5.477SerAsp: 5.477 ± 1.189
2.739SerGlu: 2.739 ± 0.903
5.477SerPhe: 5.477 ± 1.633
6.26SerGly: 6.26 ± 1.037
2.739SerHis: 2.739 ± 0.716
2.739SerIle: 2.739 ± 0.689
5.086SerLys: 5.086 ± 1.537
8.216SerLeu: 8.216 ± 1.716
1.565SerMet: 1.565 ± 0.57
3.521SerAsn: 3.521 ± 1.508
1.956SerPro: 1.956 ± 1.094
1.565SerGln: 1.565 ± 0.568
5.086SerArg: 5.086 ± 0.891
7.042SerSer: 7.042 ± 1.568
2.739SerThr: 2.739 ± 0.554
7.042SerVal: 7.042 ± 0.831
1.565SerTrp: 1.565 ± 0.674
2.739SerTyr: 2.739 ± 0.661
0.0SerXaa: 0.0 ± 0.0
Thr
5.477ThrAla: 5.477 ± 2.173
1.174ThrCys: 1.174 ± 0.458
3.13ThrAsp: 3.13 ± 0.497
2.739ThrGlu: 2.739 ± 0.882
2.347ThrPhe: 2.347 ± 0.673
3.912ThrGly: 3.912 ± 1.752
1.956ThrHis: 1.956 ± 0.939
3.912ThrIle: 3.912 ± 1.431
4.695ThrLys: 4.695 ± 1.175
6.651ThrLeu: 6.651 ± 0.614
1.174ThrMet: 1.174 ± 0.628
1.174ThrAsn: 1.174 ± 0.562
1.956ThrPro: 1.956 ± 0.953
0.782ThrGln: 0.782 ± 0.656
3.912ThrArg: 3.912 ± 1.118
5.086ThrSer: 5.086 ± 1.378
4.304ThrThr: 4.304 ± 1.003
3.912ThrVal: 3.912 ± 1.56
0.782ThrTrp: 0.782 ± 0.558
1.174ThrTyr: 1.174 ± 0.56
0.0ThrXaa: 0.0 ± 0.0
Val
3.521ValAla: 3.521 ± 1.988
1.174ValCys: 1.174 ± 0.364
7.042ValAsp: 7.042 ± 1.617
5.086ValGlu: 5.086 ± 0.769
3.13ValPhe: 3.13 ± 0.539
1.956ValGly: 1.956 ± 1.036
1.956ValHis: 1.956 ± 0.497
5.869ValIle: 5.869 ± 1.492
7.042ValLys: 7.042 ± 0.892
4.304ValLeu: 4.304 ± 1.32
1.565ValMet: 1.565 ± 0.568
1.565ValAsn: 1.565 ± 0.632
5.869ValPro: 5.869 ± 1.11
1.565ValGln: 1.565 ± 0.382
2.739ValArg: 2.739 ± 1.219
5.869ValSer: 5.869 ± 0.974
4.695ValThr: 4.695 ± 0.883
5.869ValVal: 5.869 ± 1.43
1.565ValTrp: 1.565 ± 0.446
1.174ValTyr: 1.174 ± 0.848
0.0ValXaa: 0.0 ± 0.0
Trp
1.956TrpAla: 1.956 ± 0.577
0.0TrpCys: 0.0 ± 0.0
1.174TrpAsp: 1.174 ± 0.583
1.565TrpGlu: 1.565 ± 0.382
1.174TrpPhe: 1.174 ± 0.56
0.391TrpGly: 0.391 ± 0.61
0.782TrpHis: 0.782 ± 0.604
0.391TrpIle: 0.391 ± 0.328
1.174TrpLys: 1.174 ± 0.628
1.565TrpLeu: 1.565 ± 0.568
0.782TrpMet: 0.782 ± 0.292
0.782TrpAsn: 0.782 ± 0.604
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.391TrpArg: 0.391 ± 0.268
1.174TrpSer: 1.174 ± 0.404
0.391TrpThr: 0.391 ± 0.61
0.391TrpVal: 0.391 ± 0.518
0.0TrpTrp: 0.0 ± 0.0
1.174TrpTyr: 1.174 ± 1.305
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.956TyrAla: 1.956 ± 0.576
0.782TyrCys: 0.782 ± 0.536
3.521TyrAsp: 3.521 ± 0.353
1.174TyrGlu: 1.174 ± 0.455
1.565TyrPhe: 1.565 ± 0.87
1.956TyrGly: 1.956 ± 1.094
1.565TyrHis: 1.565 ± 0.584
1.565TyrIle: 1.565 ± 0.789
1.565TyrLys: 1.565 ± 0.769
3.912TyrLeu: 3.912 ± 1.309
1.565TyrMet: 1.565 ± 0.498
0.391TyrAsn: 0.391 ± 0.268
0.0TyrPro: 0.0 ± 0.0
1.174TyrGln: 1.174 ± 0.983
2.739TyrArg: 2.739 ± 1.034
3.521TyrSer: 3.521 ± 0.831
1.956TyrThr: 1.956 ± 0.711
0.782TyrVal: 0.782 ± 0.292
0.391TyrTrp: 0.391 ± 0.268
0.782TyrTyr: 0.782 ± 0.292
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (2557 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski