Amino acid dipepetide frequency for Felis catus papillomavirus 4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.789AlaAla: 4.789 ± 1.231
1.596AlaCys: 1.596 ± 0.882
3.192AlaAsp: 3.192 ± 1.45
2.394AlaGlu: 2.394 ± 1.472
2.793AlaPhe: 2.793 ± 1.252
4.789AlaGly: 4.789 ± 1.399
0.798AlaHis: 0.798 ± 0.449
1.596AlaIle: 1.596 ± 0.864
5.587AlaLys: 5.587 ± 1.599
5.188AlaLeu: 5.188 ± 1.292
0.0AlaMet: 0.0 ± 0.0
0.798AlaAsn: 0.798 ± 0.564
3.99AlaPro: 3.99 ± 1.659
1.995AlaGln: 1.995 ± 1.091
3.192AlaArg: 3.192 ± 0.686
4.389AlaSer: 4.389 ± 1.305
4.389AlaThr: 4.389 ± 0.838
1.995AlaVal: 1.995 ± 1.022
0.399AlaTrp: 0.399 ± 0.358
0.798AlaTyr: 0.798 ± 0.395
0.0AlaXaa: 0.0 ± 0.0
Cys
1.995CysAla: 1.995 ± 0.663
2.793CysCys: 2.793 ± 2.144
1.197CysAsp: 1.197 ± 0.723
0.798CysGlu: 0.798 ± 0.592
1.596CysPhe: 1.596 ± 1.139
1.197CysGly: 1.197 ± 1.189
0.399CysHis: 0.399 ± 0.438
1.197CysIle: 1.197 ± 0.403
0.798CysLys: 0.798 ± 0.392
1.995CysLeu: 1.995 ± 1.223
0.399CysMet: 0.399 ± 0.511
1.197CysAsn: 1.197 ± 0.942
1.596CysPro: 1.596 ± 0.791
0.399CysGln: 0.399 ± 0.358
1.995CysArg: 1.995 ± 1.14
0.798CysSer: 0.798 ± 0.592
1.995CysThr: 1.995 ± 1.021
1.197CysVal: 1.197 ± 0.87
1.197CysTrp: 1.197 ± 0.566
0.798CysTyr: 0.798 ± 0.567
0.0CysXaa: 0.0 ± 0.0
Asp
3.99AspAla: 3.99 ± 0.658
3.192AspCys: 3.192 ± 1.087
3.99AspAsp: 3.99 ± 2.374
3.192AspGlu: 3.192 ± 0.898
2.394AspPhe: 2.394 ± 0.542
3.591AspGly: 3.591 ± 1.019
1.197AspHis: 1.197 ± 0.403
2.793AspIle: 2.793 ± 0.945
2.793AspLys: 2.793 ± 1.343
5.986AspLeu: 5.986 ± 1.784
0.0AspMet: 0.0 ± 0.0
1.596AspAsn: 1.596 ± 0.649
4.389AspPro: 4.389 ± 1.045
1.197AspGln: 1.197 ± 0.723
2.394AspArg: 2.394 ± 0.789
4.789AspSer: 4.789 ± 0.881
3.591AspThr: 3.591 ± 1.017
3.192AspVal: 3.192 ± 1.911
1.596AspTrp: 1.596 ± 0.982
1.197AspTyr: 1.197 ± 0.566
0.0AspXaa: 0.0 ± 0.0
Glu
5.188GluAla: 5.188 ± 1.377
0.399GluCys: 0.399 ± 0.363
7.183GluAsp: 7.183 ± 0.846
11.572GluGlu: 11.572 ± 5.402
0.399GluPhe: 0.399 ± 0.365
5.587GluGly: 5.587 ± 1.868
0.399GluHis: 0.399 ± 0.365
2.394GluIle: 2.394 ± 0.703
2.394GluLys: 2.394 ± 1.102
5.188GluLeu: 5.188 ± 1.103
1.197GluMet: 1.197 ± 0.403
2.793GluAsn: 2.793 ± 0.629
2.793GluPro: 2.793 ± 1.123
3.192GluGln: 3.192 ± 1.135
2.394GluArg: 2.394 ± 1.021
2.793GluSer: 2.793 ± 0.88
3.192GluThr: 3.192 ± 0.887
3.591GluVal: 3.591 ± 1.231
0.798GluTrp: 0.798 ± 0.449
1.197GluTyr: 1.197 ± 0.359
0.0GluXaa: 0.0 ± 0.0
Phe
1.197PheAla: 1.197 ± 0.733
1.995PheCys: 1.995 ± 1.073
3.591PheAsp: 3.591 ± 1.205
3.591PheGlu: 3.591 ± 1.835
1.995PhePhe: 1.995 ± 0.698
3.192PheGly: 3.192 ± 0.728
0.0PheHis: 0.0 ± 0.0
1.995PheIle: 1.995 ± 0.435
2.394PheLys: 2.394 ± 0.936
5.587PheLeu: 5.587 ± 1.331
0.798PheMet: 0.798 ± 0.392
1.197PheAsn: 1.197 ± 0.669
2.394PhePro: 2.394 ± 0.529
1.197PheGln: 1.197 ± 0.726
0.798PheArg: 0.798 ± 0.716
2.394PheSer: 2.394 ± 0.781
1.197PheThr: 1.197 ± 0.576
1.995PheVal: 1.995 ± 1.53
1.197PheTrp: 1.197 ± 0.394
2.394PheTyr: 2.394 ± 1.177
0.0PheXaa: 0.0 ± 0.0
Gly
5.188GlyAla: 5.188 ± 1.69
1.596GlyCys: 1.596 ± 0.777
5.587GlyAsp: 5.587 ± 1.231
5.986GlyGlu: 5.986 ± 2.788
3.192GlyPhe: 3.192 ± 0.745
15.962GlyGly: 15.962 ± 5.702
1.197GlyHis: 1.197 ± 0.631
2.394GlyIle: 2.394 ± 1.027
2.793GlyLys: 2.793 ± 0.925
6.784GlyLeu: 6.784 ± 1.351
1.197GlyMet: 1.197 ± 0.394
2.394GlyAsn: 2.394 ± 0.971
4.789GlyPro: 4.789 ± 1.331
3.591GlyGln: 3.591 ± 1.487
7.981GlyArg: 7.981 ± 3.048
7.183GlySer: 7.183 ± 1.711
4.389GlyThr: 4.389 ± 1.793
5.188GlyVal: 5.188 ± 1.208
0.399GlyTrp: 0.399 ± 0.358
1.197GlyTyr: 1.197 ± 0.359
0.399GlyXaa: 0.399 ± 0.365
His
0.798HisAla: 0.798 ± 0.392
0.399HisCys: 0.399 ± 0.349
0.0HisAsp: 0.0 ± 0.0
1.197HisGlu: 1.197 ± 0.394
0.798HisPhe: 0.798 ± 0.392
1.596HisGly: 1.596 ± 0.825
0.399HisHis: 0.399 ± 0.349
0.399HisIle: 0.399 ± 0.365
0.399HisLys: 0.399 ± 0.363
0.798HisLeu: 0.798 ± 0.395
0.798HisMet: 0.798 ± 0.716
0.0HisAsn: 0.0 ± 0.0
1.596HisPro: 1.596 ± 1.029
1.596HisGln: 1.596 ± 0.253
1.197HisArg: 1.197 ± 0.403
1.197HisSer: 1.197 ± 0.629
0.399HisThr: 0.399 ± 0.365
0.798HisVal: 0.798 ± 0.44
0.399HisTrp: 0.399 ± 0.365
1.596HisTyr: 1.596 ± 1.052
0.0HisXaa: 0.0 ± 0.0
Ile
1.596IleAla: 1.596 ± 0.774
1.197IleCys: 1.197 ± 0.756
1.596IleAsp: 1.596 ± 0.559
3.192IleGlu: 3.192 ± 1.27
1.596IlePhe: 1.596 ± 1.003
3.591IleGly: 3.591 ± 1.913
0.399IleHis: 0.399 ± 0.365
1.596IleIle: 1.596 ± 0.839
1.995IleLys: 1.995 ± 0.862
2.394IleLeu: 2.394 ± 0.739
0.798IleMet: 0.798 ± 0.449
1.197IleAsn: 1.197 ± 0.394
1.995IlePro: 1.995 ± 0.902
1.197IleGln: 1.197 ± 0.726
0.798IleArg: 0.798 ± 0.498
5.188IleSer: 5.188 ± 0.631
1.197IleThr: 1.197 ± 0.403
1.995IleVal: 1.995 ± 0.659
0.0IleTrp: 0.0 ± 0.0
1.197IleTyr: 1.197 ± 0.394
0.0IleXaa: 0.0 ± 0.0
Lys
1.596LysAla: 1.596 ± 1.067
2.793LysCys: 2.793 ± 1.193
2.394LysAsp: 2.394 ± 0.752
3.591LysGlu: 3.591 ± 0.93
3.591LysPhe: 3.591 ± 0.655
2.793LysGly: 2.793 ± 1.01
1.995LysHis: 1.995 ± 0.465
1.596LysIle: 1.596 ± 0.518
2.793LysLys: 2.793 ± 1.01
3.192LysLeu: 3.192 ± 1.453
1.197LysMet: 1.197 ± 0.656
1.596LysAsn: 1.596 ± 0.897
1.197LysPro: 1.197 ± 0.602
1.995LysGln: 1.995 ± 0.996
4.789LysArg: 4.789 ± 1.063
3.591LysSer: 3.591 ± 2.305
1.995LysThr: 1.995 ± 0.693
3.192LysVal: 3.192 ± 0.862
0.399LysTrp: 0.399 ± 0.365
1.995LysTyr: 1.995 ± 1.021
0.0LysXaa: 0.0 ± 0.0
Leu
5.188LeuAla: 5.188 ± 1.077
3.192LeuCys: 3.192 ± 1.479
5.188LeuAsp: 5.188 ± 1.192
4.789LeuGlu: 4.789 ± 0.984
3.99LeuPhe: 3.99 ± 1.075
8.779LeuGly: 8.779 ± 1.599
1.596LeuHis: 1.596 ± 0.606
1.197LeuIle: 1.197 ± 1.074
6.385LeuLys: 6.385 ± 2.067
6.385LeuLeu: 6.385 ± 2.067
2.394LeuMet: 2.394 ± 0.782
0.798LeuAsn: 0.798 ± 0.392
5.587LeuPro: 5.587 ± 1.494
7.582LeuGln: 7.582 ± 1.882
4.789LeuArg: 4.789 ± 1.443
7.981LeuSer: 7.981 ± 0.819
4.389LeuThr: 4.389 ± 2.03
5.986LeuVal: 5.986 ± 2.017
0.798LeuTrp: 0.798 ± 0.575
1.995LeuTyr: 1.995 ± 0.465
0.0LeuXaa: 0.0 ± 0.0
Met
1.197MetAla: 1.197 ± 0.834
0.399MetCys: 0.399 ± 0.365
0.798MetAsp: 0.798 ± 0.731
0.798MetGlu: 0.798 ± 0.44
0.798MetPhe: 0.798 ± 0.392
0.399MetGly: 0.399 ± 0.358
0.399MetHis: 0.399 ± 0.365
0.399MetIle: 0.399 ± 0.438
0.399MetLys: 0.399 ± 0.358
3.192MetLeu: 3.192 ± 1.72
0.399MetMet: 0.399 ± 0.363
0.798MetAsn: 0.798 ± 0.392
0.798MetPro: 0.798 ± 0.716
0.399MetGln: 0.399 ± 0.365
1.197MetArg: 1.197 ± 0.834
1.995MetSer: 1.995 ± 0.465
0.798MetThr: 0.798 ± 0.432
1.596MetVal: 1.596 ± 0.559
0.399MetTrp: 0.399 ± 0.363
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.394AsnAla: 2.394 ± 1.745
0.399AsnCys: 0.399 ± 0.358
1.596AsnAsp: 1.596 ± 0.447
1.197AsnGlu: 1.197 ± 0.586
2.394AsnPhe: 2.394 ± 0.995
1.995AsnGly: 1.995 ± 0.734
0.399AsnHis: 0.399 ± 0.438
0.798AsnIle: 0.798 ± 0.592
2.793AsnLys: 2.793 ± 1.169
2.793AsnLeu: 2.793 ± 0.623
0.798AsnMet: 0.798 ± 0.581
1.995AsnAsn: 1.995 ± 0.452
5.188AsnPro: 5.188 ± 1.522
1.197AsnGln: 1.197 ± 0.394
2.793AsnArg: 2.793 ± 0.976
0.798AsnSer: 0.798 ± 0.449
1.995AsnThr: 1.995 ± 0.996
0.399AsnVal: 0.399 ± 0.358
0.0AsnTrp: 0.0 ± 0.0
1.995AsnTyr: 1.995 ± 0.684
0.0AsnXaa: 0.0 ± 0.0
Pro
3.192ProAla: 3.192 ± 1.338
0.399ProCys: 0.399 ± 0.365
4.389ProAsp: 4.389 ± 0.901
4.789ProGlu: 4.789 ± 1.255
2.793ProPhe: 2.793 ± 0.822
3.99ProGly: 3.99 ± 2.033
0.399ProHis: 0.399 ± 0.363
1.197ProIle: 1.197 ± 0.839
3.591ProLys: 3.591 ± 1.441
7.981ProLeu: 7.981 ± 1.535
1.995ProMet: 1.995 ± 0.79
1.995ProAsn: 1.995 ± 0.625
9.577ProPro: 9.577 ± 5.984
3.192ProGln: 3.192 ± 0.796
5.986ProArg: 5.986 ± 2.703
5.587ProSer: 5.587 ± 1.715
4.389ProThr: 4.389 ± 2.304
2.793ProVal: 2.793 ± 0.936
0.399ProTrp: 0.399 ± 0.363
1.995ProTyr: 1.995 ± 0.996
0.0ProXaa: 0.0 ± 0.0
Gln
1.596GlnAla: 1.596 ± 0.635
0.0GlnCys: 0.0 ± 0.0
3.192GlnAsp: 3.192 ± 0.782
3.192GlnGlu: 3.192 ± 0.507
0.798GlnPhe: 0.798 ± 0.512
4.389GlnGly: 4.389 ± 0.869
0.399GlnHis: 0.399 ± 0.363
2.394GlnIle: 2.394 ± 0.99
0.399GlnLys: 0.399 ± 0.358
3.99GlnLeu: 3.99 ± 0.864
1.197GlnMet: 1.197 ± 0.697
1.995GlnAsn: 1.995 ± 1.021
1.596GlnPro: 1.596 ± 0.253
7.582GlnGln: 7.582 ± 3.676
3.591GlnArg: 3.591 ± 2.011
3.192GlnSer: 3.192 ± 1.168
1.995GlnThr: 1.995 ± 0.435
3.99GlnVal: 3.99 ± 0.809
0.399GlnTrp: 0.399 ± 0.358
2.793GlnTyr: 2.793 ± 1.171
0.0GlnXaa: 0.0 ± 0.0
Arg
2.793ArgAla: 2.793 ± 1.102
1.995ArgCys: 1.995 ± 1.532
0.798ArgAsp: 0.798 ± 0.608
3.591ArgGlu: 3.591 ± 1.049
1.995ArgPhe: 1.995 ± 0.377
7.981ArgGly: 7.981 ± 3.267
1.596ArgHis: 1.596 ± 0.688
2.793ArgIle: 2.793 ± 0.645
3.192ArgLys: 3.192 ± 1.317
7.582ArgLeu: 7.582 ± 1.618
0.0ArgMet: 0.0 ± 0.0
1.995ArgAsn: 1.995 ± 1.091
5.587ArgPro: 5.587 ± 1.764
4.389ArgGln: 4.389 ± 1.104
3.192ArgArg: 3.192 ± 1.279
4.389ArgSer: 4.389 ± 0.565
2.394ArgThr: 2.394 ± 1.622
4.789ArgVal: 4.789 ± 1.287
0.399ArgTrp: 0.399 ± 0.496
0.798ArgTyr: 0.798 ± 0.392
0.0ArgXaa: 0.0 ± 0.0
Ser
3.192SerAla: 3.192 ± 0.684
0.0SerCys: 0.0 ± 0.0
1.995SerAsp: 1.995 ± 0.741
3.192SerGlu: 3.192 ± 0.892
2.793SerPhe: 2.793 ± 0.855
7.183SerGly: 7.183 ± 1.71
1.995SerHis: 1.995 ± 0.908
3.591SerIle: 3.591 ± 1.485
4.389SerLys: 4.389 ± 1.534
6.784SerLeu: 6.784 ± 1.522
1.197SerMet: 1.197 ± 0.723
3.591SerAsn: 3.591 ± 1.445
5.188SerPro: 5.188 ± 1.818
2.394SerGln: 2.394 ± 0.818
5.188SerArg: 5.188 ± 1.519
14.366SerSer: 14.366 ± 5.159
6.385SerThr: 6.385 ± 2.186
8.38SerVal: 8.38 ± 2.354
1.596SerTrp: 1.596 ± 0.897
1.596SerTyr: 1.596 ± 0.608
0.0SerXaa: 0.0 ± 0.0
Thr
3.192ThrAla: 3.192 ± 1.459
1.596ThrCys: 1.596 ± 0.861
3.99ThrAsp: 3.99 ± 0.676
2.793ThrGlu: 2.793 ± 0.729
1.995ThrPhe: 1.995 ± 1.039
5.587ThrGly: 5.587 ± 1.607
0.798ThrHis: 0.798 ± 0.716
2.793ThrIle: 2.793 ± 1.117
1.995ThrLys: 1.995 ± 0.996
3.192ThrLeu: 3.192 ± 0.903
1.596ThrMet: 1.596 ± 0.998
2.394ThrAsn: 2.394 ± 0.977
6.385ThrPro: 6.385 ± 2.501
0.798ThrGln: 0.798 ± 0.45
1.197ThrArg: 1.197 ± 0.394
5.986ThrSer: 5.986 ± 1.562
5.986ThrThr: 5.986 ± 1.561
3.591ThrVal: 3.591 ± 1.048
0.399ThrTrp: 0.399 ± 0.363
1.197ThrTyr: 1.197 ± 0.717
0.0ThrXaa: 0.0 ± 0.0
Val
3.591ValAla: 3.591 ± 1.258
1.197ValCys: 1.197 ± 0.756
4.789ValAsp: 4.789 ± 1.618
3.192ValGlu: 3.192 ± 2.036
2.793ValPhe: 2.793 ± 0.869
4.789ValGly: 4.789 ± 1.887
1.197ValHis: 1.197 ± 0.653
1.197ValIle: 1.197 ± 0.669
1.995ValLys: 1.995 ± 0.663
5.587ValLeu: 5.587 ± 1.155
0.798ValMet: 0.798 ± 0.44
2.394ValAsn: 2.394 ± 0.95
3.99ValPro: 3.99 ± 1.459
3.99ValGln: 3.99 ± 2.176
3.99ValArg: 3.99 ± 1.379
6.385ValSer: 6.385 ± 1.275
4.789ValThr: 4.789 ± 1.456
3.99ValVal: 3.99 ± 0.8
0.798ValTrp: 0.798 ± 0.44
0.798ValTyr: 0.798 ± 0.392
0.0ValXaa: 0.0 ± 0.0
Trp
0.798TrpAla: 0.798 ± 0.716
0.0TrpCys: 0.0 ± 0.0
0.798TrpAsp: 0.798 ± 0.575
0.399TrpGlu: 0.399 ± 0.363
0.798TrpPhe: 0.798 ± 0.449
0.399TrpGly: 0.399 ± 0.365
0.399TrpHis: 0.399 ± 0.363
0.399TrpIle: 0.399 ± 0.358
0.798TrpLys: 0.798 ± 0.392
1.995TrpLeu: 1.995 ± 1.325
0.0TrpMet: 0.0 ± 0.0
0.399TrpAsn: 0.399 ± 0.365
0.798TrpPro: 0.798 ± 0.44
0.0TrpGln: 0.0 ± 0.0
1.197TrpArg: 1.197 ± 0.763
1.197TrpSer: 1.197 ± 0.586
0.399TrpThr: 0.399 ± 0.363
1.596TrpVal: 1.596 ± 0.614
0.399TrpTrp: 0.399 ± 0.365
0.399TrpTyr: 0.399 ± 0.511
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.197TyrAla: 1.197 ± 0.733
0.399TyrCys: 0.399 ± 0.365
0.798TyrAsp: 0.798 ± 0.395
1.197TyrGlu: 1.197 ± 0.719
1.596TyrPhe: 1.596 ± 0.559
1.596TyrGly: 1.596 ± 0.608
0.399TyrHis: 0.399 ± 0.365
1.995TyrIle: 1.995 ± 0.811
0.399TyrLys: 0.399 ± 0.363
2.394TyrLeu: 2.394 ± 1.076
0.0TyrMet: 0.0 ± 0.0
2.394TyrAsn: 2.394 ± 0.995
1.197TyrPro: 1.197 ± 0.359
1.197TyrGln: 1.197 ± 0.604
3.591TyrArg: 3.591 ± 1.114
0.798TyrSer: 0.798 ± 0.392
1.596TyrThr: 1.596 ± 0.611
1.995TyrVal: 1.995 ± 0.756
1.197TyrTrp: 1.197 ± 0.876
2.394TyrTyr: 2.394 ± 0.6
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.399XaaAsn: 0.399 ± 0.365
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (2507 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski