Amino acid dipepetide frequency for Cordyceps militaris (strain CM01) (Caterpillar fungus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	13.094AlaAla: 13.094 ± 0.088	1.252AlaCys: 1.252 ± 0.018	5.178AlaAsp: 5.178 ± 0.038	5.423AlaGlu: 5.423 ± 0.04	3.31AlaPhe: 3.31 ± 0.03	6.873AlaGly: 6.873 ± 0.045	2.172AlaHis: 2.172 ± 0.02	4.17AlaIle: 4.17 ± 0.03	4.237AlaLys: 4.237 ± 0.037	8.778AlaLeu: 8.778 ± 0.048	2.217AlaMet: 2.217 ± 0.021	3.061AlaAsn: 3.061 ± 0.027	5.591AlaPro: 5.591 ± 0.04	3.821AlaGln: 3.821 ± 0.036	6.02AlaArg: 6.02 ± 0.038	7.899AlaSer: 7.899 ± 0.047	6.147AlaThr: 6.147 ± 0.039	6.405AlaVal: 6.405 ± 0.043	1.345AlaTrp: 1.345 ± 0.019	2.253AlaTyr: 2.253 ± 0.024	0.0AlaXaa: 0.0 ± 0.0
Cys	1.131CysAla: 1.131 ± 0.015	0.276CysCys: 0.276 ± 0.009	0.683CysAsp: 0.683 ± 0.014	0.583CysGlu: 0.583 ± 0.011	0.568CysPhe: 0.568 ± 0.011	0.994CysGly: 0.994 ± 0.019	0.372CysHis: 0.372 ± 0.01	0.691CysIle: 0.691 ± 0.012	0.498CysLys: 0.498 ± 0.011	1.327CysLeu: 1.327 ± 0.019	0.272CysMet: 0.272 ± 0.008	0.433CysAsn: 0.433 ± 0.01	0.731CysPro: 0.731 ± 0.015	0.487CysGln: 0.487 ± 0.009	0.878CysArg: 0.878 ± 0.015	0.934CysSer: 0.934 ± 0.014	0.734CysThr: 0.734 ± 0.014	0.848CysVal: 0.848 ± 0.015	0.212CysTrp: 0.212 ± 0.007	0.345CysTyr: 0.345 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	5.837AspAla: 5.837 ± 0.039	0.688AspCys: 0.688 ± 0.013	4.661AspAsp: 4.661 ± 0.043	4.502AspGlu: 4.502 ± 0.039	2.164AspPhe: 2.164 ± 0.024	4.582AspGly: 4.582 ± 0.033	1.21AspHis: 1.21 ± 0.018	2.753AspIle: 2.753 ± 0.026	2.516AspLys: 2.516 ± 0.025	4.767AspLeu: 4.767 ± 0.032	1.413AspMet: 1.413 ± 0.019	1.849AspAsn: 1.849 ± 0.018	2.998AspPro: 2.998 ± 0.029	1.771AspGln: 1.771 ± 0.022	3.145AspArg: 3.145 ± 0.032	3.869AspSer: 3.869 ± 0.037	2.963AspThr: 2.963 ± 0.026	3.798AspVal: 3.798 ± 0.028	0.872AspTrp: 0.872 ± 0.013	1.509AspTyr: 1.509 ± 0.02	0.0AspXaa: 0.0 ± 0.0
Glu	5.645GluAla: 5.645 ± 0.041	0.594GluCys: 0.594 ± 0.011	3.843GluAsp: 3.843 ± 0.034	4.644GluGlu: 4.644 ± 0.053	1.81GluPhe: 1.81 ± 0.021	3.164GluGly: 3.164 ± 0.03	1.341GluHis: 1.341 ± 0.016	2.523GluIle: 2.523 ± 0.026	3.086GluLys: 3.086 ± 0.035	4.981GluLeu: 4.981 ± 0.038	1.434GluMet: 1.434 ± 0.018	1.935GluAsn: 1.935 ± 0.023	2.784GluPro: 2.784 ± 0.035	2.418GluGln: 2.418 ± 0.027	3.69GluArg: 3.69 ± 0.035	3.791GluSer: 3.791 ± 0.032	3.362GluThr: 3.362 ± 0.028	3.159GluVal: 3.159 ± 0.029	0.803GluTrp: 0.803 ± 0.013	1.56GluTyr: 1.56 ± 0.017	0.0GluXaa: 0.0 ± 0.0
Phe	3.405PheAla: 3.405 ± 0.029	0.585PheCys: 0.585 ± 0.011	2.259PheAsp: 2.259 ± 0.023	1.932PheGlu: 1.932 ± 0.023	1.62PhePhe: 1.62 ± 0.021	2.829PheGly: 2.829 ± 0.032	0.889PheHis: 0.889 ± 0.013	1.625PheIle: 1.625 ± 0.022	1.362PheLys: 1.362 ± 0.017	3.406PheLeu: 3.406 ± 0.03	0.75PheMet: 0.75 ± 0.013	1.31PheAsn: 1.31 ± 0.019	1.878PhePro: 1.878 ± 0.02	1.347PheGln: 1.347 ± 0.015	1.983PheArg: 1.983 ± 0.02	2.814PheSer: 2.814 ± 0.027	2.023PheThr: 2.023 ± 0.024	2.43PheVal: 2.43 ± 0.027	0.656PheTrp: 0.656 ± 0.012	1.062PheTyr: 1.062 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	6.265GlyAla: 6.265 ± 0.045	0.93GlyCys: 0.93 ± 0.014	3.831GlyAsp: 3.831 ± 0.03	3.467GlyGlu: 3.467 ± 0.031	2.69GlyPhe: 2.69 ± 0.03	6.441GlyGly: 6.441 ± 0.065	1.819GlyHis: 1.819 ± 0.021	3.317GlyIle: 3.317 ± 0.027	3.254GlyLys: 3.254 ± 0.027	6.174GlyLeu: 6.174 ± 0.036	1.56GlyMet: 1.56 ± 0.021	2.429GlyAsn: 2.429 ± 0.023	3.42GlyPro: 3.42 ± 0.03	2.614GlyGln: 2.614 ± 0.027	4.528GlyArg: 4.528 ± 0.035	5.618GlySer: 5.618 ± 0.038	4.03GlyThr: 4.03 ± 0.034	4.428GlyVal: 4.428 ± 0.036	1.201GlyTrp: 1.201 ± 0.017	2.08GlyTyr: 2.08 ± 0.025	0.0GlyXaa: 0.0 ± 0.0
His	2.214HisAla: 2.214 ± 0.023	0.366HisCys: 0.366 ± 0.009	1.457HisAsp: 1.457 ± 0.018	1.248HisGlu: 1.248 ± 0.016	0.915HisPhe: 0.915 ± 0.013	1.916HisGly: 1.916 ± 0.022	0.972HisHis: 0.972 ± 0.022	1.184HisIle: 1.184 ± 0.017	0.897HisLys: 0.897 ± 0.014	2.299HisLeu: 2.299 ± 0.022	0.551HisMet: 0.551 ± 0.011	0.837HisAsn: 0.837 ± 0.013	1.626HisPro: 1.626 ± 0.02	1.015HisGln: 1.015 ± 0.016	1.655HisArg: 1.655 ± 0.019	1.789HisSer: 1.789 ± 0.021	1.316HisThr: 1.316 ± 0.018	1.567HisVal: 1.567 ± 0.02	0.366HisTrp: 0.366 ± 0.009	0.675HisTyr: 0.675 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	4.149IleAla: 4.149 ± 0.032	0.688IleCys: 0.688 ± 0.014	2.625IleAsp: 2.625 ± 0.024	2.427IleGlu: 2.427 ± 0.022	1.791IlePhe: 1.791 ± 0.02	2.997IleGly: 2.997 ± 0.03	1.1IleHis: 1.1 ± 0.014	2.241IleIle: 2.241 ± 0.024	1.956IleLys: 1.956 ± 0.023	4.218IleLeu: 4.218 ± 0.037	1.032IleMet: 1.032 ± 0.015	1.576IleAsn: 1.576 ± 0.019	2.69IlePro: 2.69 ± 0.024	1.664IleGln: 1.664 ± 0.022	2.655IleArg: 2.655 ± 0.022	3.358IleSer: 3.358 ± 0.03	2.564IleThr: 2.564 ± 0.023	3.02IleVal: 3.02 ± 0.027	0.647IleTrp: 0.647 ± 0.011	1.245IleTyr: 1.245 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	4.159LysAla: 4.159 ± 0.036	0.465LysCys: 0.465 ± 0.011	2.524LysAsp: 2.524 ± 0.028	2.801LysGlu: 2.801 ± 0.033	1.354LysPhe: 1.354 ± 0.018	2.597LysGly: 2.597 ± 0.025	1.064LysHis: 1.064 ± 0.015	1.996LysIle: 1.996 ± 0.025	3.017LysLys: 3.017 ± 0.041	3.919LysLeu: 3.919 ± 0.032	1.05LysMet: 1.05 ± 0.014	1.566LysAsn: 1.566 ± 0.02	2.56LysPro: 2.56 ± 0.021	1.824LysGln: 1.824 ± 0.021	3.231LysArg: 3.231 ± 0.028	3.21LysSer: 3.21 ± 0.031	2.835LysThr: 2.835 ± 0.024	2.56LysVal: 2.56 ± 0.026	0.607LysTrp: 0.607 ± 0.012	1.233LysTyr: 1.233 ± 0.016	0.0LysXaa: 0.0 ± 0.0
Leu	9.109LeuAla: 9.109 ± 0.055	1.309LeuCys: 1.309 ± 0.018	5.245LeuAsp: 5.245 ± 0.038	5.035LeuGlu: 5.035 ± 0.041	3.4LeuPhe: 3.4 ± 0.031	6.131LeuGly: 6.131 ± 0.041	2.371LeuHis: 2.371 ± 0.025	3.561LeuIle: 3.561 ± 0.038	3.617LeuLys: 3.617 ± 0.029	8.707LeuLeu: 8.707 ± 0.071	1.744LeuMet: 1.744 ± 0.021	2.787LeuAsn: 2.787 ± 0.025	5.713LeuPro: 5.713 ± 0.039	3.932LeuGln: 3.932 ± 0.031	6.154LeuArg: 6.154 ± 0.043	7.016LeuSer: 7.016 ± 0.041	4.814LeuThr: 4.814 ± 0.033	5.908LeuVal: 5.908 ± 0.044	1.236LeuTrp: 1.236 ± 0.019	2.301LeuTyr: 2.301 ± 0.023	0.0LeuXaa: 0.0 ± 0.0
Met	2.505MetAla: 2.505 ± 0.023	0.259MetCys: 0.259 ± 0.008	1.313MetAsp: 1.313 ± 0.017	1.243MetGlu: 1.243 ± 0.017	0.694MetPhe: 0.694 ± 0.013	1.469MetGly: 1.469 ± 0.019	0.527MetHis: 0.527 ± 0.011	0.896MetIle: 0.896 ± 0.014	0.938MetLys: 0.938 ± 0.015	1.948MetLeu: 1.948 ± 0.021	0.615MetMet: 0.615 ± 0.012	0.738MetAsn: 0.738 ± 0.014	1.398MetPro: 1.398 ± 0.02	0.908MetGln: 0.908 ± 0.016	1.393MetArg: 1.393 ± 0.018	1.844MetSer: 1.844 ± 0.018	1.395MetThr: 1.395 ± 0.016	1.343MetVal: 1.343 ± 0.017	0.258MetTrp: 0.258 ± 0.007	0.561MetTyr: 0.561 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.068AsnAla: 3.068 ± 0.028	0.438AsnCys: 0.438 ± 0.01	1.82AsnAsp: 1.82 ± 0.019	1.73AsnGlu: 1.73 ± 0.022	1.232AsnPhe: 1.232 ± 0.018	2.794AsnGly: 2.794 ± 0.032	0.813AsnHis: 0.813 ± 0.013	1.779AsnIle: 1.779 ± 0.022	1.522AsnLys: 1.522 ± 0.019	2.983AsnLeu: 2.983 ± 0.025	0.873AsnMet: 0.873 ± 0.013	1.349AsnAsn: 1.349 ± 0.023	2.164AsnPro: 2.164 ± 0.022	1.175AsnGln: 1.175 ± 0.021	1.856AsnArg: 1.856 ± 0.018	2.429AsnSer: 2.429 ± 0.025	2.008AsnThr: 2.008 ± 0.023	2.187AsnVal: 2.187 ± 0.021	0.516AsnTrp: 0.516 ± 0.01	0.962AsnTyr: 0.962 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	6.287ProAla: 6.287 ± 0.046	0.624ProCys: 0.624 ± 0.011	3.263ProAsp: 3.263 ± 0.027	3.474ProGlu: 3.474 ± 0.031	2.003ProPhe: 2.003 ± 0.023	4.11ProGly: 4.11 ± 0.036	1.341ProHis: 1.341 ± 0.015	2.281ProIle: 2.281 ± 0.025	2.445ProLys: 2.445 ± 0.027	4.888ProLeu: 4.888 ± 0.036	1.125ProMet: 1.125 ± 0.016	1.987ProAsn: 1.987 ± 0.02	5.534ProPro: 5.534 ± 0.071	2.427ProGln: 2.427 ± 0.029	3.767ProArg: 3.767 ± 0.031	5.634ProSer: 5.634 ± 0.038	3.877ProThr: 3.877 ± 0.031	3.749ProVal: 3.749 ± 0.029	0.777ProTrp: 0.777 ± 0.013	1.378ProTyr: 1.378 ± 0.018	0.0ProXaa: 0.0 ± 0.0
Gln	3.68GlnAla: 3.68 ± 0.032	0.446GlnCys: 0.446 ± 0.011	2.169GlnAsp: 2.169 ± 0.024	2.129GlnGlu: 2.129 ± 0.022	1.294GlnPhe: 1.294 ± 0.018	2.439GlnGly: 2.439 ± 0.028	1.201GlnHis: 1.201 ± 0.019	1.693GlnIle: 1.693 ± 0.02	1.814GlnLys: 1.814 ± 0.018	3.561GlnLeu: 3.561 ± 0.028	0.896GlnMet: 0.896 ± 0.015	1.384GlnAsn: 1.384 ± 0.02	2.64GlnPro: 2.64 ± 0.03	2.619GlnGln: 2.619 ± 0.063	2.846GlnArg: 2.846 ± 0.028	2.952GlnSer: 2.952 ± 0.032	2.305GlnThr: 2.305 ± 0.02	2.284GlnVal: 2.284 ± 0.024	0.552GlnTrp: 0.552 ± 0.011	1.126GlnTyr: 1.126 ± 0.014	0.0GlnXaa: 0.0 ± 0.0
Arg	5.7ArgAla: 5.7 ± 0.039	0.842ArgCys: 0.842 ± 0.014	3.724ArgAsp: 3.724 ± 0.04	3.564ArgGlu: 3.564 ± 0.034	2.225ArgPhe: 2.225 ± 0.02	4.162ArgGly: 4.162 ± 0.034	1.817ArgHis: 1.817 ± 0.023	2.822ArgIle: 2.822 ± 0.026	3.141ArgLys: 3.141 ± 0.03	5.932ArgLeu: 5.932 ± 0.039	1.346ArgMet: 1.346 ± 0.016	2.167ArgAsn: 2.167 ± 0.022	3.854ArgPro: 3.854 ± 0.034	2.837ArgGln: 2.837 ± 0.028	5.76ArgArg: 5.76 ± 0.053	4.761ArgSer: 4.761 ± 0.037	3.332ArgThr: 3.332 ± 0.029	3.654ArgVal: 3.654 ± 0.033	0.978ArgTrp: 0.978 ± 0.016	1.655ArgTyr: 1.655 ± 0.02	0.0ArgXaa: 0.0 ± 0.0
Ser	7.193SerAla: 7.193 ± 0.045	0.94SerCys: 0.94 ± 0.014	4.063SerAsp: 4.063 ± 0.033	3.602SerGlu: 3.602 ± 0.035	2.876SerPhe: 2.876 ± 0.026	5.366SerGly: 5.366 ± 0.039	1.944SerHis: 1.944 ± 0.021	3.636SerIle: 3.636 ± 0.032	3.354SerLys: 3.354 ± 0.03	7.012SerLeu: 7.012 ± 0.047	1.685SerMet: 1.685 ± 0.018	2.655SerAsn: 2.655 ± 0.026	5.228SerPro: 5.228 ± 0.051	3.045SerGln: 3.045 ± 0.03	5.029SerArg: 5.029 ± 0.044	8.181SerSer: 8.181 ± 0.08	5.15SerThr: 5.15 ± 0.044	4.577SerVal: 4.577 ± 0.035	1.098SerTrp: 1.098 ± 0.015	1.915SerTyr: 1.915 ± 0.021	0.0SerXaa: 0.0 ± 0.0
Thr	5.916ThrAla: 5.916 ± 0.037	0.768ThrCys: 0.768 ± 0.014	2.883ThrAsp: 2.883 ± 0.025	2.969ThrGlu: 2.969 ± 0.027	2.113ThrPhe: 2.113 ± 0.019	4.157ThrGly: 4.157 ± 0.035	1.314ThrHis: 1.314 ± 0.017	2.824ThrIle: 2.824 ± 0.026	2.524ThrLys: 2.524 ± 0.028	5.287ThrLeu: 5.287 ± 0.033	1.3ThrMet: 1.3 ± 0.016	1.953ThrAsn: 1.953 ± 0.022	4.311ThrPro: 4.311 ± 0.036	2.037ThrGln: 2.037 ± 0.022	3.342ThrArg: 3.342 ± 0.025	5.037ThrSer: 5.037 ± 0.04	4.428ThrThr: 4.428 ± 0.049	3.792ThrVal: 3.792 ± 0.033	0.831ThrTrp: 0.831 ± 0.012	1.526ThrTyr: 1.526 ± 0.017	0.0ThrXaa: 0.0 ± 0.0
Val	6.383ValAla: 6.383 ± 0.045	0.91ValCys: 0.91 ± 0.016	3.862ValAsp: 3.862 ± 0.027	3.59ValGlu: 3.59 ± 0.028	2.457ValPhe: 2.457 ± 0.024	4.16ValGly: 4.16 ± 0.035	1.47ValHis: 1.47 ± 0.017	2.702ValIle: 2.702 ± 0.027	2.626ValLys: 2.626 ± 0.025	5.945ValLeu: 5.945 ± 0.041	1.376ValMet: 1.376 ± 0.017	2.049ValAsn: 2.049 ± 0.021	3.781ValPro: 3.781 ± 0.031	2.446ValGln: 2.446 ± 0.024	3.731ValArg: 3.731 ± 0.029	4.518ValSer: 4.518 ± 0.036	3.568ValThr: 3.568 ± 0.031	4.663ValVal: 4.663 ± 0.036	0.896ValTrp: 0.896 ± 0.015	1.71ValTyr: 1.71 ± 0.017	0.0ValXaa: 0.0 ± 0.0
Trp	1.235TrpAla: 1.235 ± 0.015	0.212TrpCys: 0.212 ± 0.006	0.872TrpAsp: 0.872 ± 0.015	0.778TrpGlu: 0.778 ± 0.015	0.529TrpPhe: 0.529 ± 0.012	0.916TrpGly: 0.916 ± 0.015	0.384TrpHis: 0.384 ± 0.01	0.69TrpIle: 0.69 ± 0.013	0.697TrpLys: 0.697 ± 0.012	1.422TrpLeu: 1.422 ± 0.019	0.361TrpMet: 0.361 ± 0.008	0.586TrpAsn: 0.586 ± 0.012	0.676TrpPro: 0.676 ± 0.012	0.617TrpGln: 0.617 ± 0.011	1.046TrpArg: 1.046 ± 0.017	1.05TrpSer: 1.05 ± 0.015	0.911TrpThr: 0.911 ± 0.014	0.88TrpVal: 0.88 ± 0.014	0.29TrpTrp: 0.29 ± 0.009	0.424TrpTyr: 0.424 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.271TyrAla: 2.271 ± 0.026	0.402TyrCys: 0.402 ± 0.009	1.592TyrAsp: 1.592 ± 0.021	1.427TyrGlu: 1.427 ± 0.019	1.123TyrPhe: 1.123 ± 0.018	1.998TyrGly: 1.998 ± 0.023	0.745TyrHis: 0.745 ± 0.012	1.259TyrIle: 1.259 ± 0.017	1.069TyrLys: 1.069 ± 0.015	2.536TyrLeu: 2.536 ± 0.026	0.648TyrMet: 0.648 ± 0.011	1.046TyrAsn: 1.046 ± 0.014	1.393TyrPro: 1.393 ± 0.018	1.025TyrGln: 1.025 ± 0.016	1.565TyrArg: 1.565 ± 0.018	1.85TyrSer: 1.85 ± 0.024	1.547TyrThr: 1.547 ± 0.019	1.59TyrVal: 1.59 ± 0.018	0.433TyrTrp: 0.433 ± 0.01	0.882TyrTyr: 0.882 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 9651 proteins (4871812 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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