Amino acid dipepetide frequency for Circovirus-like genome DCCV-12

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.887AlaAla: 6.887 ± 0.724
1.377AlaCys: 1.377 ± 0.961
6.887AlaAsp: 6.887 ± 2.425
5.51AlaGlu: 5.51 ± 1.691
2.755AlaPhe: 2.755 ± 0.846
2.755AlaGly: 2.755 ± 0.846
2.755AlaHis: 2.755 ± 1.922
4.132AlaIle: 4.132 ± 1.46
2.755AlaLys: 2.755 ± 1.922
4.132AlaLeu: 4.132 ± 1.673
2.755AlaMet: 2.755 ± 1.888
6.887AlaAsn: 6.887 ± 6.537
5.51AlaPro: 5.51 ± 2.679
4.132AlaGln: 4.132 ± 2.882
4.132AlaArg: 4.132 ± 4.451
6.887AlaSer: 6.887 ± 3.609
2.755AlaThr: 2.755 ± 2.141
4.132AlaVal: 4.132 ± 2.447
0.0AlaTrp: 0.0 ± 0.0
2.755AlaTyr: 2.755 ± 0.846
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
2.755CysAsp: 2.755 ± 1.922
0.0CysGlu: 0.0 ± 0.0
1.377CysPhe: 1.377 ± 0.961
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.377CysLeu: 1.377 ± 0.961
1.377CysMet: 1.377 ± 1.616
0.0CysAsn: 0.0 ± 0.0
1.377CysPro: 1.377 ± 0.961
2.755CysGln: 2.755 ± 1.922
1.377CysArg: 1.377 ± 0.961
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
1.377CysTrp: 1.377 ± 0.961
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.132AspAla: 4.132 ± 1.46
1.377AspCys: 1.377 ± 0.961
2.755AspAsp: 2.755 ± 1.922
8.264AspGlu: 8.264 ± 5.765
4.132AspPhe: 4.132 ± 3.212
4.132AspGly: 4.132 ± 3.212
0.0AspHis: 0.0 ± 0.0
2.755AspIle: 2.755 ± 0.846
4.132AspLys: 4.132 ± 1.673
1.377AspLeu: 1.377 ± 0.961
0.0AspMet: 0.0 ± 0.0
1.377AspAsn: 1.377 ± 0.961
5.51AspPro: 5.51 ± 2.322
0.0AspGln: 0.0 ± 0.0
1.377AspArg: 1.377 ± 0.961
0.0AspSer: 0.0 ± 0.0
1.377AspThr: 1.377 ± 1.071
2.755AspVal: 2.755 ± 0.846
0.0AspTrp: 0.0 ± 0.0
1.377AspTyr: 1.377 ± 0.961
0.0AspXaa: 0.0 ± 0.0
Glu
5.51GluAla: 5.51 ± 2.322
0.0GluCys: 0.0 ± 0.0
2.755GluAsp: 2.755 ± 2.141
4.132GluGlu: 4.132 ± 2.882
1.377GluPhe: 1.377 ± 0.961
1.377GluGly: 1.377 ± 0.961
0.0GluHis: 0.0 ± 0.0
5.51GluIle: 5.51 ± 2.322
1.377GluLys: 1.377 ± 0.961
5.51GluLeu: 5.51 ± 2.322
1.377GluMet: 1.377 ± 0.961
0.0GluAsn: 0.0 ± 0.0
5.51GluPro: 5.51 ± 1.691
1.377GluGln: 1.377 ± 0.961
4.132GluArg: 4.132 ± 2.882
2.755GluSer: 2.755 ± 0.846
1.377GluThr: 1.377 ± 0.961
1.377GluVal: 1.377 ± 0.961
1.377GluTrp: 1.377 ± 0.961
2.755GluTyr: 2.755 ± 1.922
0.0GluXaa: 0.0 ± 0.0
Phe
1.377PheAla: 1.377 ± 1.071
2.755PheCys: 2.755 ± 1.922
1.377PheAsp: 1.377 ± 0.961
2.755PheGlu: 2.755 ± 1.922
2.755PhePhe: 2.755 ± 2.141
0.0PheGly: 0.0 ± 0.0
1.377PheHis: 1.377 ± 2.378
1.377PheIle: 1.377 ± 0.961
6.887PheLys: 6.887 ± 2.425
2.755PheLeu: 2.755 ± 2.141
0.0PheMet: 0.0 ± 0.0
9.642PheAsn: 9.642 ± 3.224
2.755PhePro: 2.755 ± 2.171
2.755PheGln: 2.755 ± 0.846
0.0PheArg: 0.0 ± 0.0
1.377PheSer: 1.377 ± 0.961
2.755PheThr: 2.755 ± 1.922
1.377PheVal: 1.377 ± 1.071
0.0PheTrp: 0.0 ± 0.0
1.377PheTyr: 1.377 ± 1.071
0.0PheXaa: 0.0 ± 0.0
Gly
2.755GlyAla: 2.755 ± 0.846
1.377GlyCys: 1.377 ± 0.961
1.377GlyAsp: 1.377 ± 1.071
5.51GlyGlu: 5.51 ± 2.322
1.377GlyPhe: 1.377 ± 0.961
0.0GlyGly: 0.0 ± 0.0
0.0GlyHis: 0.0 ± 0.0
2.755GlyIle: 2.755 ± 4.757
1.377GlyLys: 1.377 ± 0.961
4.132GlyLeu: 4.132 ± 1.46
0.0GlyMet: 0.0 ± 0.0
1.377GlyAsn: 1.377 ± 1.071
4.132GlyPro: 4.132 ± 3.212
4.132GlyGln: 4.132 ± 1.46
4.132GlyArg: 4.132 ± 1.673
1.377GlySer: 1.377 ± 1.071
6.887GlyThr: 6.887 ± 4.492
5.51GlyVal: 5.51 ± 1.386
4.132GlyTrp: 4.132 ± 2.882
1.377GlyTyr: 1.377 ± 1.071
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
1.377HisAsp: 1.377 ± 0.961
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
1.377HisIle: 1.377 ± 0.961
0.0HisLys: 0.0 ± 0.0
4.132HisLeu: 4.132 ± 2.882
0.0HisMet: 0.0 ± 0.0
1.377HisAsn: 1.377 ± 1.071
1.377HisPro: 1.377 ± 0.961
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
4.132HisSer: 4.132 ± 4.418
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
4.132HisTyr: 4.132 ± 1.46
0.0HisXaa: 0.0 ± 0.0
Ile
2.755IleAla: 2.755 ± 2.171
2.755IleCys: 2.755 ± 1.922
1.377IleAsp: 1.377 ± 1.071
2.755IleGlu: 2.755 ± 0.846
2.755IlePhe: 2.755 ± 0.846
5.51IleGly: 5.51 ± 2.679
2.755IleHis: 2.755 ± 1.922
2.755IleIle: 2.755 ± 2.162
9.642IleLys: 9.642 ± 4.336
1.377IleLeu: 1.377 ± 0.961
0.0IleMet: 0.0 ± 0.0
0.0IleAsn: 0.0 ± 0.0
5.51IlePro: 5.51 ± 1.386
0.0IleGln: 0.0 ± 0.0
4.132IleArg: 4.132 ± 1.541
2.755IleSer: 2.755 ± 2.162
5.51IleThr: 5.51 ± 3.918
1.377IleVal: 1.377 ± 0.961
0.0IleTrp: 0.0 ± 0.0
1.377IleTyr: 1.377 ± 2.378
0.0IleXaa: 0.0 ± 0.0
Lys
6.887LysAla: 6.887 ± 3.24
0.0LysCys: 0.0 ± 0.0
0.0LysAsp: 0.0 ± 0.0
0.0LysGlu: 0.0 ± 0.0
0.0LysPhe: 0.0 ± 0.0
5.51LysGly: 5.51 ± 2.322
0.0LysHis: 0.0 ± 0.0
2.755LysIle: 2.755 ± 1.922
4.132LysLys: 4.132 ± 1.673
8.264LysLeu: 8.264 ± 4.776
5.51LysMet: 5.51 ± 4.282
1.377LysAsn: 1.377 ± 1.071
5.51LysPro: 5.51 ± 2.679
0.0LysGln: 0.0 ± 0.0
15.152LysArg: 15.152 ± 4.87
1.377LysSer: 1.377 ± 0.961
2.755LysThr: 2.755 ± 1.922
5.51LysVal: 5.51 ± 2.322
2.755LysTrp: 2.755 ± 2.171
4.132LysTyr: 4.132 ± 1.46
0.0LysXaa: 0.0 ± 0.0
Leu
11.019LeuAla: 11.019 ± 2.255
0.0LeuCys: 0.0 ± 0.0
5.51LeuAsp: 5.51 ± 2.322
2.755LeuGlu: 2.755 ± 1.922
5.51LeuPhe: 5.51 ± 1.386
4.132LeuGly: 4.132 ± 1.673
1.377LeuHis: 1.377 ± 2.378
4.132LeuIle: 4.132 ± 4.418
5.51LeuLys: 5.51 ± 1.691
2.755LeuLeu: 2.755 ± 4.757
0.0LeuMet: 0.0 ± 0.0
4.132LeuAsn: 4.132 ± 1.673
1.377LeuPro: 1.377 ± 2.378
2.755LeuGln: 2.755 ± 0.846
2.755LeuArg: 2.755 ± 2.171
2.755LeuSer: 2.755 ± 1.922
4.132LeuThr: 4.132 ± 1.673
6.887LeuVal: 6.887 ± 2.14
0.0LeuTrp: 0.0 ± 0.0
4.132LeuTyr: 4.132 ± 1.673
0.0LeuXaa: 0.0 ± 0.0
Met
4.132MetAla: 4.132 ± 2.447
0.0MetCys: 0.0 ± 0.0
2.755MetAsp: 2.755 ± 1.922
0.0MetGlu: 0.0 ± 0.0
2.755MetPhe: 2.755 ± 2.141
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
1.377MetIle: 1.377 ± 1.071
1.377MetLys: 1.377 ± 1.071
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
2.755MetAsn: 2.755 ± 2.171
1.377MetPro: 1.377 ± 0.961
1.377MetGln: 1.377 ± 1.071
2.755MetArg: 2.755 ± 2.171
1.377MetSer: 1.377 ± 2.378
1.377MetThr: 1.377 ± 2.378
2.755MetVal: 2.755 ± 2.141
1.377MetTrp: 1.377 ± 1.071
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.755AsnAla: 2.755 ± 4.757
0.0AsnCys: 0.0 ± 0.0
4.132AsnAsp: 4.132 ± 1.673
1.377AsnGlu: 1.377 ± 0.961
4.132AsnPhe: 4.132 ± 1.673
5.51AsnGly: 5.51 ± 1.386
0.0AsnHis: 0.0 ± 0.0
2.755AsnIle: 2.755 ± 1.922
0.0AsnLys: 0.0 ± 0.0
5.51AsnLeu: 5.51 ± 1.527
1.377AsnMet: 1.377 ± 1.071
5.51AsnAsn: 5.51 ± 2.679
1.377AsnPro: 1.377 ± 1.071
5.51AsnGln: 5.51 ± 2.679
2.755AsnArg: 2.755 ± 2.171
2.755AsnSer: 2.755 ± 0.846
2.755AsnThr: 2.755 ± 2.141
5.51AsnVal: 5.51 ± 1.527
0.0AsnTrp: 0.0 ± 0.0
5.51AsnTyr: 5.51 ± 2.322
0.0AsnXaa: 0.0 ± 0.0
Pro
9.642ProAla: 9.642 ± 2.146
0.0ProCys: 0.0 ± 0.0
0.0ProAsp: 0.0 ± 0.0
4.132ProGlu: 4.132 ± 1.46
2.755ProPhe: 2.755 ± 1.922
5.51ProGly: 5.51 ± 1.386
0.0ProHis: 0.0 ± 0.0
1.377ProIle: 1.377 ± 0.961
6.887ProLys: 6.887 ± 2.183
4.132ProLeu: 4.132 ± 1.673
1.377ProMet: 1.377 ± 1.071
4.132ProAsn: 4.132 ± 1.673
1.377ProPro: 1.377 ± 0.961
1.377ProGln: 1.377 ± 0.961
2.755ProArg: 2.755 ± 2.171
5.51ProSer: 5.51 ± 6.758
5.51ProThr: 5.51 ± 1.691
4.132ProVal: 4.132 ± 3.212
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
1.377GlnGlu: 1.377 ± 0.961
2.755GlnPhe: 2.755 ± 0.846
4.132GlnGly: 4.132 ± 1.673
1.377GlnHis: 1.377 ± 1.071
4.132GlnIle: 4.132 ± 1.673
4.132GlnLys: 4.132 ± 2.882
1.377GlnLeu: 1.377 ± 0.961
1.377GlnMet: 1.377 ± 0.961
1.377GlnAsn: 1.377 ± 0.961
0.0GlnPro: 0.0 ± 0.0
2.755GlnGln: 2.755 ± 1.922
1.377GlnArg: 1.377 ± 1.071
0.0GlnSer: 0.0 ± 0.0
1.377GlnThr: 1.377 ± 0.961
4.132GlnVal: 4.132 ± 1.541
0.0GlnTrp: 0.0 ± 0.0
1.377GlnTyr: 1.377 ± 1.071
0.0GlnXaa: 0.0 ± 0.0
Arg
4.132ArgAla: 4.132 ± 1.673
1.377ArgCys: 1.377 ± 2.378
2.755ArgAsp: 2.755 ± 1.922
2.755ArgGlu: 2.755 ± 0.846
4.132ArgPhe: 4.132 ± 2.882
4.132ArgGly: 4.132 ± 1.673
1.377ArgHis: 1.377 ± 0.961
4.132ArgIle: 4.132 ± 3.212
8.264ArgLys: 8.264 ± 2.537
8.264ArgLeu: 8.264 ± 11.533
1.377ArgMet: 1.377 ± 1.071
4.132ArgAsn: 4.132 ± 1.46
4.132ArgPro: 4.132 ± 2.369
0.0ArgGln: 0.0 ± 0.0
12.397ArgArg: 12.397 ± 5.036
6.887ArgSer: 6.887 ± 9.118
1.377ArgThr: 1.377 ± 0.961
2.755ArgVal: 2.755 ± 2.141
1.377ArgTrp: 1.377 ± 1.071
1.377ArgTyr: 1.377 ± 1.071
0.0ArgXaa: 0.0 ± 0.0
Ser
1.377SerAla: 1.377 ± 0.961
0.0SerCys: 0.0 ± 0.0
1.377SerAsp: 1.377 ± 1.071
1.377SerGlu: 1.377 ± 0.961
2.755SerPhe: 2.755 ± 2.171
4.132SerGly: 4.132 ± 1.541
0.0SerHis: 0.0 ± 0.0
4.132SerIle: 4.132 ± 4.451
2.755SerLys: 2.755 ± 2.171
4.132SerLeu: 4.132 ± 1.541
4.132SerMet: 4.132 ± 4.418
5.51SerAsn: 5.51 ± 3.918
1.377SerPro: 1.377 ± 1.071
2.755SerGln: 2.755 ± 2.162
4.132SerArg: 4.132 ± 4.418
9.642SerSer: 9.642 ± 8.677
2.755SerThr: 2.755 ± 2.162
1.377SerVal: 1.377 ± 0.961
0.0SerTrp: 0.0 ± 0.0
4.132SerTyr: 4.132 ± 2.447
0.0SerXaa: 0.0 ± 0.0
Thr
4.132ThrAla: 4.132 ± 1.541
0.0ThrCys: 0.0 ± 0.0
2.755ThrAsp: 2.755 ± 1.922
1.377ThrGlu: 1.377 ± 1.071
1.377ThrPhe: 1.377 ± 1.071
1.377ThrGly: 1.377 ± 0.961
2.755ThrHis: 2.755 ± 0.846
5.51ThrIle: 5.51 ± 4.282
2.755ThrLys: 2.755 ± 0.846
4.132ThrLeu: 4.132 ± 2.447
1.377ThrMet: 1.377 ± 2.378
1.377ThrAsn: 1.377 ± 1.071
1.377ThrPro: 1.377 ± 2.378
0.0ThrGln: 0.0 ± 0.0
4.132ThrArg: 4.132 ± 1.541
5.51ThrSer: 5.51 ± 3.918
5.51ThrThr: 5.51 ± 6.799
2.755ThrVal: 2.755 ± 0.846
4.132ThrTrp: 4.132 ± 1.46
1.377ThrTyr: 1.377 ± 0.961
0.0ThrXaa: 0.0 ± 0.0
Val
4.132ValAla: 4.132 ± 1.46
0.0ValCys: 0.0 ± 0.0
4.132ValAsp: 4.132 ± 1.46
1.377ValGlu: 1.377 ± 0.961
1.377ValPhe: 1.377 ± 0.961
1.377ValGly: 1.377 ± 2.378
0.0ValHis: 0.0 ± 0.0
4.132ValIle: 4.132 ± 1.541
5.51ValLys: 5.51 ± 1.691
6.887ValLeu: 6.887 ± 0.724
2.755ValMet: 2.755 ± 2.231
4.132ValAsn: 4.132 ± 1.673
8.264ValPro: 8.264 ± 3.02
1.377ValGln: 1.377 ± 1.071
4.132ValArg: 4.132 ± 2.447
2.755ValSer: 2.755 ± 2.141
1.377ValThr: 1.377 ± 1.071
5.51ValVal: 5.51 ± 1.691
0.0ValTrp: 0.0 ± 0.0
4.132ValTyr: 4.132 ± 1.673
0.0ValXaa: 0.0 ± 0.0
Trp
1.377TrpAla: 1.377 ± 1.071
1.377TrpCys: 1.377 ± 0.961
1.377TrpAsp: 1.377 ± 1.071
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
1.377TrpHis: 1.377 ± 0.961
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
2.755TrpAsn: 2.755 ± 1.922
1.377TrpPro: 1.377 ± 0.961
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
4.132TrpThr: 4.132 ± 1.541
2.755TrpVal: 2.755 ± 1.922
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
6.887TyrAla: 6.887 ± 3.721
2.755TyrCys: 2.755 ± 1.922
1.377TyrAsp: 1.377 ± 0.961
4.132TyrGlu: 4.132 ± 1.46
1.377TyrPhe: 1.377 ± 1.071
4.132TyrGly: 4.132 ± 2.369
2.755TyrHis: 2.755 ± 0.846
0.0TyrIle: 0.0 ± 0.0
4.132TyrLys: 4.132 ± 1.673
1.377TyrLeu: 1.377 ± 0.961
1.377TyrMet: 1.377 ± 0.961
1.377TyrAsn: 1.377 ± 0.961
1.377TyrPro: 1.377 ± 0.961
0.0TyrGln: 0.0 ± 0.0
5.51TyrArg: 5.51 ± 4.282
0.0TyrSer: 0.0 ± 0.0
0.0TyrThr: 0.0 ± 0.0
2.755TyrVal: 2.755 ± 2.162
0.0TyrTrp: 0.0 ± 0.0
4.132TyrTyr: 4.132 ± 2.882
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (727 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski