Amino acid dipepetide frequency for Verticillium dahliae (strain VdLs.17 / ATCC MYA-4575 / FGSC 10137) (Verticillium wilt)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.894AlaAla: 11.894 ± 0.09
1.182AlaCys: 1.182 ± 0.02
5.058AlaAsp: 5.058 ± 0.034
5.653AlaGlu: 5.653 ± 0.039
3.284AlaPhe: 3.284 ± 0.03
6.873AlaGly: 6.873 ± 0.052
2.052AlaHis: 2.052 ± 0.021
4.12AlaIle: 4.12 ± 0.035
4.237AlaLys: 4.237 ± 0.036
8.386AlaLeu: 8.386 ± 0.05
2.201AlaMet: 2.201 ± 0.023
3.099AlaAsn: 3.099 ± 0.028
5.933AlaPro: 5.933 ± 0.052
3.794AlaGln: 3.794 ± 0.04
5.859AlaArg: 5.859 ± 0.039
8.05AlaSer: 8.05 ± 0.047
5.842AlaThr: 5.842 ± 0.037
6.134AlaVal: 6.134 ± 0.041
1.337AlaTrp: 1.337 ± 0.018
2.176AlaTyr: 2.176 ± 0.021
0.0AlaXaa: 0.0 ± 0.0
Cys
1.008CysAla: 1.008 ± 0.018
0.257CysCys: 0.257 ± 0.01
0.679CysAsp: 0.679 ± 0.013
0.581CysGlu: 0.581 ± 0.012
0.509CysPhe: 0.509 ± 0.01
0.979CysGly: 0.979 ± 0.024
0.348CysHis: 0.348 ± 0.009
0.634CysIle: 0.634 ± 0.013
0.468CysLys: 0.468 ± 0.013
1.207CysLeu: 1.207 ± 0.019
0.263CysMet: 0.263 ± 0.008
0.419CysAsn: 0.419 ± 0.011
0.676CysPro: 0.676 ± 0.015
0.442CysGln: 0.442 ± 0.011
0.803CysArg: 0.803 ± 0.015
0.865CysSer: 0.865 ± 0.015
0.694CysThr: 0.694 ± 0.016
0.803CysVal: 0.803 ± 0.022
0.19CysTrp: 0.19 ± 0.007
0.32CysTyr: 0.32 ± 0.009
0.0CysXaa: 0.0 ± 0.0
Asp
5.7AspAla: 5.7 ± 0.04
0.625AspCys: 0.625 ± 0.014
4.983AspAsp: 4.983 ± 0.052
4.686AspGlu: 4.686 ± 0.041
2.215AspPhe: 2.215 ± 0.023
4.529AspGly: 4.529 ± 0.038
1.297AspHis: 1.297 ± 0.016
2.746AspIle: 2.746 ± 0.024
2.419AspLys: 2.419 ± 0.022
5.06AspLeu: 5.06 ± 0.038
1.364AspMet: 1.364 ± 0.016
1.823AspAsn: 1.823 ± 0.022
3.331AspPro: 3.331 ± 0.029
1.869AspGln: 1.869 ± 0.021
3.219AspArg: 3.219 ± 0.032
3.92AspSer: 3.92 ± 0.034
2.936AspThr: 2.936 ± 0.026
3.962AspVal: 3.962 ± 0.032
0.905AspTrp: 0.905 ± 0.013
1.514AspTyr: 1.514 ± 0.019
0.0AspXaa: 0.0 ± 0.0
Glu
6.097GluAla: 6.097 ± 0.043
0.588GluCys: 0.588 ± 0.012
4.203GluAsp: 4.203 ± 0.039
4.984GluGlu: 4.984 ± 0.059
1.753GluPhe: 1.753 ± 0.02
3.836GluGly: 3.836 ± 0.03
1.365GluHis: 1.365 ± 0.022
2.563GluIle: 2.563 ± 0.026
3.237GluLys: 3.237 ± 0.032
4.972GluLeu: 4.972 ± 0.036
1.382GluMet: 1.382 ± 0.019
1.95GluAsn: 1.95 ± 0.022
3.019GluPro: 3.019 ± 0.056
2.362GluGln: 2.362 ± 0.024
3.924GluArg: 3.924 ± 0.035
3.894GluSer: 3.894 ± 0.032
3.521GluThr: 3.521 ± 0.033
3.554GluVal: 3.554 ± 0.03
0.8GluTrp: 0.8 ± 0.013
1.5GluTyr: 1.5 ± 0.019
0.0GluXaa: 0.0 ± 0.0
Phe
3.253PheAla: 3.253 ± 0.03
0.539PheCys: 0.539 ± 0.012
2.326PheAsp: 2.326 ± 0.023
2.075PheGlu: 2.075 ± 0.021
1.579PhePhe: 1.579 ± 0.024
2.878PheGly: 2.878 ± 0.03
0.854PheHis: 0.854 ± 0.013
1.616PheIle: 1.616 ± 0.02
1.366PheLys: 1.366 ± 0.018
3.25PheLeu: 3.25 ± 0.031
0.759PheMet: 0.759 ± 0.012
1.325PheAsn: 1.325 ± 0.019
1.826PhePro: 1.826 ± 0.019
1.301PheGln: 1.301 ± 0.015
1.947PheArg: 1.947 ± 0.021
2.686PheSer: 2.686 ± 0.024
2.035PheThr: 2.035 ± 0.024
2.414PheVal: 2.414 ± 0.027
0.631PheTrp: 0.631 ± 0.013
0.987PheTyr: 0.987 ± 0.016
0.0PheXaa: 0.0 ± 0.0
Gly
6.293GlyAla: 6.293 ± 0.048
0.896GlyCys: 0.896 ± 0.017
3.981GlyAsp: 3.981 ± 0.034
3.65GlyGlu: 3.65 ± 0.028
2.817GlyPhe: 2.817 ± 0.033
6.615GlyGly: 6.615 ± 0.068
1.854GlyHis: 1.854 ± 0.022
3.306GlyIle: 3.306 ± 0.031
3.275GlyLys: 3.275 ± 0.034
6.253GlyLeu: 6.253 ± 0.036
1.617GlyMet: 1.617 ± 0.021
2.535GlyAsn: 2.535 ± 0.032
3.746GlyPro: 3.746 ± 0.037
2.758GlyGln: 2.758 ± 0.033
4.652GlyArg: 4.652 ± 0.036
5.812GlySer: 5.812 ± 0.041
4.136GlyThr: 4.136 ± 0.035
4.599GlyVal: 4.599 ± 0.041
1.177GlyTrp: 1.177 ± 0.019
1.991GlyTyr: 1.991 ± 0.024
0.0GlyXaa: 0.0 ± 0.0
His
2.159HisAla: 2.159 ± 0.023
0.328HisCys: 0.328 ± 0.009
1.474HisAsp: 1.474 ± 0.018
1.352HisGlu: 1.352 ± 0.015
0.889HisPhe: 0.889 ± 0.012
1.907HisGly: 1.907 ± 0.024
0.907HisHis: 0.907 ± 0.016
1.122HisIle: 1.122 ± 0.016
0.876HisLys: 0.876 ± 0.014
2.222HisLeu: 2.222 ± 0.023
0.534HisMet: 0.534 ± 0.011
0.804HisAsn: 0.804 ± 0.013
1.637HisPro: 1.637 ± 0.02
1.057HisGln: 1.057 ± 0.019
1.633HisArg: 1.633 ± 0.023
1.686HisSer: 1.686 ± 0.023
1.242HisThr: 1.242 ± 0.015
1.591HisVal: 1.591 ± 0.017
0.343HisTrp: 0.343 ± 0.008
0.653HisTyr: 0.653 ± 0.013
0.0HisXaa: 0.0 ± 0.0
Ile
4.034IleAla: 4.034 ± 0.032
0.656IleCys: 0.656 ± 0.016
2.712IleAsp: 2.712 ± 0.023
2.592IleGlu: 2.592 ± 0.025
1.752IlePhe: 1.752 ± 0.021
2.956IleGly: 2.956 ± 0.033
1.078IleHis: 1.078 ± 0.016
2.199IleIle: 2.199 ± 0.028
1.919IleLys: 1.919 ± 0.023
4.015IleLeu: 4.015 ± 0.038
0.989IleMet: 0.989 ± 0.016
1.599IleAsn: 1.599 ± 0.018
2.652IlePro: 2.652 ± 0.03
1.629IleGln: 1.629 ± 0.019
2.642IleArg: 2.642 ± 0.025
3.266IleSer: 3.266 ± 0.025
2.55IleThr: 2.55 ± 0.027
3.041IleVal: 3.041 ± 0.028
0.663IleTrp: 0.663 ± 0.013
1.173IleTyr: 1.173 ± 0.016
0.0IleXaa: 0.0 ± 0.0
Lys
4.445LysAla: 4.445 ± 0.041
0.455LysCys: 0.455 ± 0.01
2.6LysAsp: 2.6 ± 0.027
2.917LysGlu: 2.917 ± 0.031
1.314LysPhe: 1.314 ± 0.016
2.872LysGly: 2.872 ± 0.031
1.059LysHis: 1.059 ± 0.016
1.947LysIle: 1.947 ± 0.022
3.205LysLys: 3.205 ± 0.069
3.736LysLeu: 3.736 ± 0.037
0.948LysMet: 0.948 ± 0.014
1.559LysAsn: 1.559 ± 0.018
2.664LysPro: 2.664 ± 0.026
1.711LysGln: 1.711 ± 0.021
3.223LysArg: 3.223 ± 0.03
3.104LysSer: 3.104 ± 0.032
2.844LysThr: 2.844 ± 0.027
2.659LysVal: 2.659 ± 0.025
0.609LysTrp: 0.609 ± 0.011
1.177LysTyr: 1.177 ± 0.017
0.0LysXaa: 0.0 ± 0.0
Leu
8.616LeuAla: 8.616 ± 0.046
1.135LeuCys: 1.135 ± 0.016
5.17LeuAsp: 5.17 ± 0.039
5.22LeuGlu: 5.22 ± 0.04
3.156LeuPhe: 3.156 ± 0.032
6.019LeuGly: 6.019 ± 0.039
2.207LeuHis: 2.207 ± 0.024
3.508LeuIle: 3.508 ± 0.034
3.766LeuLys: 3.766 ± 0.035
8.083LeuLeu: 8.083 ± 0.056
1.746LeuMet: 1.746 ± 0.019
2.84LeuAsn: 2.84 ± 0.024
5.552LeuPro: 5.552 ± 0.04
3.625LeuGln: 3.625 ± 0.029
5.909LeuArg: 5.909 ± 0.037
6.745LeuSer: 6.745 ± 0.041
4.878LeuThr: 4.878 ± 0.035
5.57LeuVal: 5.57 ± 0.038
1.177LeuTrp: 1.177 ± 0.015
2.138LeuTyr: 2.138 ± 0.021
0.0LeuXaa: 0.0 ± 0.0
Met
2.496MetAla: 2.496 ± 0.024
0.24MetCys: 0.24 ± 0.007
1.254MetAsp: 1.254 ± 0.016
1.173MetGlu: 1.173 ± 0.017
0.723MetPhe: 0.723 ± 0.012
1.508MetGly: 1.508 ± 0.019
0.498MetHis: 0.498 ± 0.009
0.907MetIle: 0.907 ± 0.014
0.948MetLys: 0.948 ± 0.012
1.815MetLeu: 1.815 ± 0.021
0.586MetMet: 0.586 ± 0.011
0.754MetAsn: 0.754 ± 0.012
1.372MetPro: 1.372 ± 0.019
0.814MetGln: 0.814 ± 0.017
1.337MetArg: 1.337 ± 0.019
1.84MetSer: 1.84 ± 0.017
1.382MetThr: 1.382 ± 0.017
1.326MetVal: 1.326 ± 0.016
0.261MetTrp: 0.261 ± 0.008
0.508MetTyr: 0.508 ± 0.01
0.0MetXaa: 0.0 ± 0.0
Asn
3.094AsnAla: 3.094 ± 0.027
0.413AsnCys: 0.413 ± 0.011
1.927AsnAsp: 1.927 ± 0.02
1.826AsnGlu: 1.826 ± 0.019
1.247AsnPhe: 1.247 ± 0.014
2.949AsnGly: 2.949 ± 0.031
0.797AsnHis: 0.797 ± 0.013
1.748AsnIle: 1.748 ± 0.02
1.448AsnLys: 1.448 ± 0.019
2.989AsnLeu: 2.989 ± 0.026
0.812AsnMet: 0.812 ± 0.013
1.373AsnAsn: 1.373 ± 0.025
2.294AsnPro: 2.294 ± 0.021
1.177AsnGln: 1.177 ± 0.017
1.854AsnArg: 1.854 ± 0.021
2.341AsnSer: 2.341 ± 0.024
2.03AsnThr: 2.03 ± 0.023
2.244AsnVal: 2.244 ± 0.023
0.512AsnTrp: 0.512 ± 0.011
0.924AsnTyr: 0.924 ± 0.014
0.0AsnXaa: 0.0 ± 0.0
Pro
6.422ProAla: 6.422 ± 0.059
0.572ProCys: 0.572 ± 0.016
3.359ProAsp: 3.359 ± 0.03
3.844ProGlu: 3.844 ± 0.04
2.009ProPhe: 2.009 ± 0.02
4.364ProGly: 4.364 ± 0.04
1.372ProHis: 1.372 ± 0.019
2.303ProIle: 2.303 ± 0.025
2.546ProLys: 2.546 ± 0.027
4.863ProLeu: 4.863 ± 0.034
1.126ProMet: 1.126 ± 0.017
2.021ProAsn: 2.021 ± 0.023
5.51ProPro: 5.51 ± 0.068
2.526ProGln: 2.526 ± 0.035
3.809ProArg: 3.809 ± 0.034
6.053ProSer: 6.053 ± 0.058
4.109ProThr: 4.109 ± 0.037
3.866ProVal: 3.866 ± 0.037
0.771ProTrp: 0.771 ± 0.013
1.413ProTyr: 1.413 ± 0.018
0.0ProXaa: 0.0 ± 0.0
Gln
3.85GlnAla: 3.85 ± 0.034
0.442GlnCys: 0.442 ± 0.011
2.109GlnAsp: 2.109 ± 0.023
2.179GlnGlu: 2.179 ± 0.022
1.163GlnPhe: 1.163 ± 0.017
2.602GlnGly: 2.602 ± 0.032
1.187GlnHis: 1.187 ± 0.022
1.663GlnIle: 1.663 ± 0.017
1.813GlnLys: 1.813 ± 0.022
3.303GlnLeu: 3.303 ± 0.031
0.877GlnMet: 0.877 ± 0.015
1.357GlnAsn: 1.357 ± 0.019
2.691GlnPro: 2.691 ± 0.031
2.932GlnGln: 2.932 ± 0.073
2.692GlnArg: 2.692 ± 0.022
2.919GlnSer: 2.919 ± 0.03
2.332GlnThr: 2.332 ± 0.022
2.208GlnVal: 2.208 ± 0.022
0.566GlnTrp: 0.566 ± 0.01
1.084GlnTyr: 1.084 ± 0.016
0.0GlnXaa: 0.0 ± 0.0
Arg
5.517ArgAla: 5.517 ± 0.033
0.771ArgCys: 0.771 ± 0.014
3.728ArgAsp: 3.728 ± 0.037
3.795ArgGlu: 3.795 ± 0.033
2.147ArgPhe: 2.147 ± 0.02
4.149ArgGly: 4.149 ± 0.037
1.793ArgHis: 1.793 ± 0.02
2.747ArgIle: 2.747 ± 0.023
3.26ArgLys: 3.26 ± 0.031
5.566ArgLeu: 5.566 ± 0.036
1.372ArgMet: 1.372 ± 0.019
2.174ArgAsn: 2.174 ± 0.019
3.966ArgPro: 3.966 ± 0.032
2.849ArgGln: 2.849 ± 0.027
5.735ArgArg: 5.735 ± 0.055
4.83ArgSer: 4.83 ± 0.045
3.47ArgThr: 3.47 ± 0.024
3.501ArgVal: 3.501 ± 0.024
0.996ArgTrp: 0.996 ± 0.014
1.593ArgTyr: 1.593 ± 0.017
0.0ArgXaa: 0.0 ± 0.0
Ser
7.048SerAla: 7.048 ± 0.044
0.858SerCys: 0.858 ± 0.013
4.163SerAsp: 4.163 ± 0.033
3.792SerGlu: 3.792 ± 0.03
2.862SerPhe: 2.862 ± 0.025
5.568SerGly: 5.568 ± 0.041
1.912SerHis: 1.912 ± 0.022
3.504SerIle: 3.504 ± 0.033
3.291SerLys: 3.291 ± 0.034
6.785SerLeu: 6.785 ± 0.043
1.673SerMet: 1.673 ± 0.02
2.693SerAsn: 2.693 ± 0.027
5.489SerPro: 5.489 ± 0.055
3.097SerGln: 3.097 ± 0.031
5.11SerArg: 5.11 ± 0.045
8.333SerSer: 8.333 ± 0.078
5.293SerThr: 5.293 ± 0.042
4.472SerVal: 4.472 ± 0.03
1.112SerTrp: 1.112 ± 0.016
1.87SerTyr: 1.87 ± 0.023
0.0SerXaa: 0.0 ± 0.0
Thr
5.843ThrAla: 5.843 ± 0.037
0.768ThrCys: 0.768 ± 0.023
2.932ThrAsp: 2.932 ± 0.024
3.019ThrGlu: 3.019 ± 0.029
2.119ThrPhe: 2.119 ± 0.02
4.234ThrGly: 4.234 ± 0.037
1.309ThrHis: 1.309 ± 0.017
2.86ThrIle: 2.86 ± 0.023
2.497ThrLys: 2.497 ± 0.028
5.145ThrLeu: 5.145 ± 0.034
1.218ThrMet: 1.218 ± 0.015
2.006ThrAsn: 2.006 ± 0.019
4.588ThrPro: 4.588 ± 0.043
2.12ThrGln: 2.12 ± 0.021
3.376ThrArg: 3.376 ± 0.03
5.207ThrSer: 5.207 ± 0.039
4.455ThrThr: 4.455 ± 0.045
3.754ThrVal: 3.754 ± 0.033
0.893ThrTrp: 0.893 ± 0.013
1.491ThrTyr: 1.491 ± 0.017
0.0ThrXaa: 0.0 ± 0.0
Val
6.007ValAla: 6.007 ± 0.042
0.849ValCys: 0.849 ± 0.018
3.913ValAsp: 3.913 ± 0.03
3.918ValGlu: 3.918 ± 0.034
2.469ValPhe: 2.469 ± 0.026
4.157ValGly: 4.157 ± 0.038
1.424ValHis: 1.424 ± 0.019
2.753ValIle: 2.753 ± 0.026
2.782ValLys: 2.782 ± 0.029
5.696ValLeu: 5.696 ± 0.043
1.343ValMet: 1.343 ± 0.018
2.105ValAsn: 2.105 ± 0.024
3.872ValPro: 3.872 ± 0.035
2.335ValGln: 2.335 ± 0.023
3.694ValArg: 3.694 ± 0.027
4.563ValSer: 4.563 ± 0.032
3.695ValThr: 3.695 ± 0.031
4.511ValVal: 4.511 ± 0.033
0.905ValTrp: 0.905 ± 0.015
1.641ValTyr: 1.641 ± 0.018
0.0ValXaa: 0.0 ± 0.0
Trp
1.247TrpAla: 1.247 ± 0.018
0.204TrpCys: 0.204 ± 0.006
0.909TrpAsp: 0.909 ± 0.015
0.802TrpGlu: 0.802 ± 0.014
0.553TrpPhe: 0.553 ± 0.012
0.963TrpGly: 0.963 ± 0.017
0.389TrpHis: 0.389 ± 0.01
0.682TrpIle: 0.682 ± 0.013
0.72TrpLys: 0.72 ± 0.011
1.336TrpLeu: 1.336 ± 0.02
0.364TrpMet: 0.364 ± 0.009
0.59TrpAsn: 0.59 ± 0.011
0.664TrpPro: 0.664 ± 0.011
0.596TrpGln: 0.596 ± 0.012
0.988TrpArg: 0.988 ± 0.014
1.043TrpSer: 1.043 ± 0.013
0.936TrpThr: 0.936 ± 0.014
0.875TrpVal: 0.875 ± 0.014
0.281TrpTrp: 0.281 ± 0.008
0.413TrpTyr: 0.413 ± 0.01
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.141TyrAla: 2.141 ± 0.019
0.368TyrCys: 0.368 ± 0.01
1.625TyrAsp: 1.625 ± 0.02
1.447TyrGlu: 1.447 ± 0.019
1.086TyrPhe: 1.086 ± 0.017
2.006TyrGly: 2.006 ± 0.025
0.713TyrHis: 0.713 ± 0.013
1.192TyrIle: 1.192 ± 0.016
0.974TyrLys: 0.974 ± 0.017
2.38TyrLeu: 2.38 ± 0.023
0.565TyrMet: 0.565 ± 0.01
0.972TyrAsn: 0.972 ± 0.013
1.376TyrPro: 1.376 ± 0.021
0.974TyrGln: 0.974 ± 0.016
1.553TyrArg: 1.553 ± 0.017
1.766TyrSer: 1.766 ± 0.019
1.457TyrThr: 1.457 ± 0.019
1.548TyrVal: 1.548 ± 0.017
0.425TyrTrp: 0.425 ± 0.011
0.798TyrTyr: 0.798 ± 0.015
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 10530 proteins (4983248 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski