Amino acid dipepetide frequency for Xanthomonas phage phiLf (Bacteriophage phi-Lf)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
13.158AlaAla: 13.158 ± 3.199
2.193AlaCys: 2.193 ± 0.9
6.579AlaAsp: 6.579 ± 1.501
2.193AlaGlu: 2.193 ± 1.038
2.741AlaPhe: 2.741 ± 1.149
8.772AlaGly: 8.772 ± 3.079
0.548AlaHis: 0.548 ± 0.548
4.934AlaIle: 4.934 ± 1.189
6.031AlaLys: 6.031 ± 1.753
7.127AlaLeu: 7.127 ± 1.503
2.741AlaMet: 2.741 ± 1.279
2.741AlaAsn: 2.741 ± 1.335
7.127AlaPro: 7.127 ± 1.878
1.645AlaGln: 1.645 ± 0.611
10.965AlaArg: 10.965 ± 2.718
7.675AlaSer: 7.675 ± 1.337
7.675AlaThr: 7.675 ± 1.731
7.675AlaVal: 7.675 ± 2.464
4.386AlaTrp: 4.386 ± 1.33
0.548AlaTyr: 0.548 ± 0.428
0.0AlaXaa: 0.0 ± 0.0
Cys
0.548CysAla: 0.548 ± 0.428
0.548CysCys: 0.548 ± 0.682
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
3.838CysGly: 3.838 ± 1.282
0.0CysHis: 0.0 ± 0.0
0.548CysIle: 0.548 ± 0.448
0.548CysLys: 0.548 ± 0.59
0.0CysLeu: 0.0 ± 0.0
0.548CysMet: 0.548 ± 0.59
0.548CysAsn: 0.548 ± 0.428
1.645CysPro: 1.645 ± 1.261
0.0CysGln: 0.0 ± 0.0
1.096CysArg: 1.096 ± 0.724
1.645CysSer: 1.645 ± 0.791
1.645CysThr: 1.645 ± 0.538
2.193CysVal: 2.193 ± 1.024
0.0CysTrp: 0.0 ± 0.0
0.548CysTyr: 0.548 ± 0.428
0.0CysXaa: 0.0 ± 0.0
Asp
8.224AspAla: 8.224 ± 1.239
0.548AspCys: 0.548 ± 0.63
2.741AspAsp: 2.741 ± 2.142
2.193AspGlu: 2.193 ± 1.302
2.193AspPhe: 2.193 ± 1.214
15.899AspGly: 15.899 ± 8.107
0.0AspHis: 0.0 ± 0.0
2.193AspIle: 2.193 ± 0.877
1.096AspLys: 1.096 ± 0.642
4.386AspLeu: 4.386 ± 1.376
0.0AspMet: 0.0 ± 0.0
1.096AspAsn: 1.096 ± 0.642
3.289AspPro: 3.289 ± 1.105
4.934AspGln: 4.934 ± 0.868
4.934AspArg: 4.934 ± 1.717
0.548AspSer: 0.548 ± 0.548
2.193AspThr: 2.193 ± 0.78
2.741AspVal: 2.741 ± 0.699
0.0AspTrp: 0.0 ± 0.0
0.548AspTyr: 0.548 ± 0.428
0.0AspXaa: 0.0 ± 0.0
Glu
3.838GluAla: 3.838 ± 1.628
0.0GluCys: 0.0 ± 0.0
1.096GluAsp: 1.096 ± 1.048
2.193GluGlu: 2.193 ± 0.866
3.289GluPhe: 3.289 ± 1.105
4.386GluGly: 4.386 ± 1.659
0.0GluHis: 0.0 ± 0.0
1.096GluIle: 1.096 ± 1.096
3.838GluLys: 3.838 ± 1.182
4.934GluLeu: 4.934 ± 1.716
0.0GluMet: 0.0 ± 0.0
1.645GluAsn: 1.645 ± 1.344
1.096GluPro: 1.096 ± 0.612
2.741GluGln: 2.741 ± 0.947
0.548GluArg: 0.548 ± 0.448
3.289GluSer: 3.289 ± 1.033
0.0GluThr: 0.0 ± 0.0
1.096GluVal: 1.096 ± 0.896
0.0GluTrp: 0.0 ± 0.0
1.096GluTyr: 1.096 ± 0.642
0.0GluXaa: 0.0 ± 0.0
Phe
4.386PheAla: 4.386 ± 0.902
0.548PheCys: 0.548 ± 0.548
2.741PheAsp: 2.741 ± 1.458
0.548PheGlu: 0.548 ± 0.448
3.289PhePhe: 3.289 ± 1.125
3.838PheGly: 3.838 ± 1.882
1.096PheHis: 1.096 ± 0.512
1.096PheIle: 1.096 ± 0.634
1.096PheLys: 1.096 ± 0.581
3.838PheLeu: 3.838 ± 1.357
2.193PheMet: 2.193 ± 1.234
2.741PheAsn: 2.741 ± 0.704
4.386PhePro: 4.386 ± 1.34
0.548PheGln: 0.548 ± 0.448
4.386PheArg: 4.386 ± 2.401
1.645PheSer: 1.645 ± 1.285
2.741PheThr: 2.741 ± 0.94
1.645PheVal: 1.645 ± 1.068
1.645PheTrp: 1.645 ± 0.608
1.096PheTyr: 1.096 ± 0.658
0.0PheXaa: 0.0 ± 0.0
Gly
9.32GlyAla: 9.32 ± 2.296
2.193GlyCys: 2.193 ± 0.88
16.447GlyAsp: 16.447 ± 9.459
6.031GlyGlu: 6.031 ± 2.305
3.289GlyPhe: 3.289 ± 0.923
26.316GlyGly: 26.316 ± 9.3
1.096GlyHis: 1.096 ± 0.634
2.193GlyIle: 2.193 ± 0.931
5.482GlyLys: 5.482 ± 1.624
4.386GlyLeu: 4.386 ± 2.024
4.386GlyMet: 4.386 ± 1.502
1.096GlyAsn: 1.096 ± 0.724
2.741GlyPro: 2.741 ± 1.008
2.741GlyGln: 2.741 ± 1.205
7.127GlyArg: 7.127 ± 0.859
6.579GlySer: 6.579 ± 1.064
3.838GlyThr: 3.838 ± 1.33
7.675GlyVal: 7.675 ± 1.997
3.838GlyTrp: 3.838 ± 1.498
4.934GlyTyr: 4.934 ± 1.063
0.0GlyXaa: 0.0 ± 0.0
His
0.548HisAla: 0.548 ± 0.428
0.548HisCys: 0.548 ± 0.428
0.548HisAsp: 0.548 ± 0.548
0.548HisGlu: 0.548 ± 0.448
1.645HisPhe: 1.645 ± 0.928
2.741HisGly: 2.741 ± 1.205
0.0HisHis: 0.0 ± 0.0
1.645HisIle: 1.645 ± 0.945
0.0HisLys: 0.0 ± 0.0
1.096HisLeu: 1.096 ± 0.896
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.548HisPro: 0.548 ± 0.548
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
0.548HisSer: 0.548 ± 0.448
0.548HisThr: 0.548 ± 0.448
2.193HisVal: 2.193 ± 0.649
0.0HisTrp: 0.0 ± 0.0
2.193HisTyr: 2.193 ± 0.974
0.0HisXaa: 0.0 ± 0.0
Ile
3.838IleAla: 3.838 ± 1.694
0.0IleCys: 0.0 ± 0.0
3.289IleAsp: 3.289 ± 0.581
3.289IleGlu: 3.289 ± 0.953
2.741IlePhe: 2.741 ± 0.854
4.386IleGly: 4.386 ± 2.207
0.548IleHis: 0.548 ± 0.428
1.096IleIle: 1.096 ± 0.929
0.0IleLys: 0.0 ± 0.0
3.289IleLeu: 3.289 ± 1.697
2.193IleMet: 2.193 ± 0.962
1.096IleAsn: 1.096 ± 0.512
1.096IlePro: 1.096 ± 0.658
2.741IleGln: 2.741 ± 1.127
6.031IleArg: 6.031 ± 0.825
0.0IleSer: 0.0 ± 0.0
1.645IleThr: 1.645 ± 1.069
1.096IleVal: 1.096 ± 0.702
0.548IleTrp: 0.548 ± 0.63
0.548IleTyr: 0.548 ± 0.448
0.0IleXaa: 0.0 ± 0.0
Lys
4.386LysAla: 4.386 ± 1.635
0.0LysCys: 0.0 ± 0.0
3.838LysAsp: 3.838 ± 1.54
0.0LysGlu: 0.0 ± 0.0
2.741LysPhe: 2.741 ± 0.683
7.127LysGly: 7.127 ± 1.194
1.645LysHis: 1.645 ± 0.945
0.548LysIle: 0.548 ± 0.548
3.289LysLys: 3.289 ± 0.951
1.645LysLeu: 1.645 ± 0.929
0.0LysMet: 0.0 ± 0.0
2.741LysAsn: 2.741 ± 1.423
2.741LysPro: 2.741 ± 1.279
0.0LysGln: 0.0 ± 0.0
3.289LysArg: 3.289 ± 1.564
3.838LysSer: 3.838 ± 0.976
1.096LysThr: 1.096 ± 0.612
6.031LysVal: 6.031 ± 2.004
1.645LysTrp: 1.645 ± 0.85
1.645LysTyr: 1.645 ± 0.608
0.0LysXaa: 0.0 ± 0.0
Leu
7.127LeuAla: 7.127 ± 1.043
0.548LeuCys: 0.548 ± 0.548
2.193LeuAsp: 2.193 ± 0.715
1.096LeuGlu: 1.096 ± 1.011
2.193LeuPhe: 2.193 ± 0.529
8.224LeuGly: 8.224 ± 1.644
1.096LeuHis: 1.096 ± 0.581
1.096LeuIle: 1.096 ± 0.709
2.193LeuLys: 2.193 ± 0.86
2.741LeuLeu: 2.741 ± 1.338
0.548LeuMet: 0.548 ± 0.617
1.645LeuAsn: 1.645 ± 0.608
1.645LeuPro: 1.645 ± 0.971
2.741LeuGln: 2.741 ± 1.22
4.934LeuArg: 4.934 ± 0.674
5.482LeuSer: 5.482 ± 1.518
8.772LeuThr: 8.772 ± 1.832
4.386LeuVal: 4.386 ± 1.797
2.193LeuTrp: 2.193 ± 0.75
2.741LeuTyr: 2.741 ± 0.989
0.0LeuXaa: 0.0 ± 0.0
Met
4.934MetAla: 4.934 ± 1.683
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
1.645MetPhe: 1.645 ± 0.957
1.096MetGly: 1.096 ± 0.841
0.548MetHis: 0.548 ± 0.448
2.193MetIle: 2.193 ± 2.208
2.741MetLys: 2.741 ± 1.073
2.741MetLeu: 2.741 ± 0.549
1.096MetMet: 1.096 ± 0.613
0.0MetAsn: 0.0 ± 0.0
1.096MetPro: 1.096 ± 1.082
1.096MetGln: 1.096 ± 1.096
1.645MetArg: 1.645 ± 0.876
1.645MetSer: 1.645 ± 0.985
1.645MetThr: 1.645 ± 0.831
1.645MetVal: 1.645 ± 0.625
0.548MetTrp: 0.548 ± 0.63
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.645AsnAla: 1.645 ± 0.687
1.096AsnCys: 1.096 ± 0.634
1.645AsnAsp: 1.645 ± 0.668
1.096AsnGlu: 1.096 ± 0.896
1.096AsnPhe: 1.096 ± 0.512
2.741AsnGly: 2.741 ± 1.229
0.548AsnHis: 0.548 ± 0.448
0.0AsnIle: 0.0 ± 0.0
2.741AsnLys: 2.741 ± 0.821
0.0AsnLeu: 0.0 ± 0.0
1.096AsnMet: 1.096 ± 0.642
2.193AsnAsn: 2.193 ± 0.715
0.548AsnPro: 0.548 ± 0.428
0.0AsnGln: 0.0 ± 0.0
3.289AsnArg: 3.289 ± 1.255
0.0AsnSer: 0.0 ± 0.0
3.289AsnThr: 3.289 ± 0.763
1.645AsnVal: 1.645 ± 0.945
0.0AsnTrp: 0.0 ± 0.0
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
6.579ProAla: 6.579 ± 2.404
0.0ProCys: 0.0 ± 0.0
5.482ProAsp: 5.482 ± 2.046
0.548ProGlu: 0.548 ± 0.548
0.548ProPhe: 0.548 ± 0.635
2.741ProGly: 2.741 ± 0.896
2.193ProHis: 2.193 ± 1.268
3.838ProIle: 3.838 ± 0.984
3.289ProLys: 3.289 ± 1.373
3.289ProLeu: 3.289 ± 1.105
2.741ProMet: 2.741 ± 1.017
0.548ProAsn: 0.548 ± 0.448
4.934ProPro: 4.934 ± 1.846
1.096ProGln: 1.096 ± 0.634
2.193ProArg: 2.193 ± 0.831
6.031ProSer: 6.031 ± 2.085
3.289ProThr: 3.289 ± 0.908
0.548ProVal: 0.548 ± 0.428
2.193ProTrp: 2.193 ± 0.649
0.548ProTyr: 0.548 ± 0.635
0.0ProXaa: 0.0 ± 0.0
Gln
1.096GlnAla: 1.096 ± 1.096
0.548GlnCys: 0.548 ± 0.59
2.193GlnAsp: 2.193 ± 1.085
2.741GlnGlu: 2.741 ± 1.148
0.0GlnPhe: 0.0 ± 0.0
3.289GlnGly: 3.289 ± 0.639
0.548GlnHis: 0.548 ± 0.448
1.645GlnIle: 1.645 ± 0.928
1.096GlnLys: 1.096 ± 0.581
3.289GlnLeu: 3.289 ± 1.125
1.096GlnMet: 1.096 ± 0.642
1.096GlnAsn: 1.096 ± 0.658
2.741GlnPro: 2.741 ± 1.22
1.096GlnGln: 1.096 ± 1.27
4.934GlnArg: 4.934 ± 1.716
2.193GlnSer: 2.193 ± 1.168
2.741GlnThr: 2.741 ± 0.836
1.645GlnVal: 1.645 ± 0.625
1.645GlnTrp: 1.645 ± 0.945
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
9.32ArgAla: 9.32 ± 1.815
0.0ArgCys: 0.0 ± 0.0
2.193ArgAsp: 2.193 ± 0.967
7.127ArgGlu: 7.127 ± 3.044
2.193ArgPhe: 2.193 ± 0.683
4.386ArgGly: 4.386 ± 1.269
0.0ArgHis: 0.0 ± 0.0
3.838ArgIle: 3.838 ± 0.874
2.193ArgLys: 2.193 ± 0.974
9.32ArgLeu: 9.32 ± 1.794
2.741ArgMet: 2.741 ± 1.263
1.096ArgAsn: 1.096 ± 0.634
1.645ArgPro: 1.645 ± 0.645
0.548ArgGln: 0.548 ± 0.428
3.289ArgArg: 3.289 ± 0.944
1.645ArgSer: 1.645 ± 1.4
4.386ArgThr: 4.386 ± 1.532
4.386ArgVal: 4.386 ± 0.921
3.289ArgTrp: 3.289 ± 1.751
2.741ArgTyr: 2.741 ± 0.819
0.0ArgXaa: 0.0 ± 0.0
Ser
7.127SerAla: 7.127 ± 2.033
1.096SerCys: 1.096 ± 0.612
3.289SerAsp: 3.289 ± 0.908
1.096SerGlu: 1.096 ± 0.612
3.289SerPhe: 3.289 ± 1.739
6.031SerGly: 6.031 ± 1.763
0.0SerHis: 0.0 ± 0.0
1.096SerIle: 1.096 ± 0.724
4.386SerLys: 4.386 ± 1.399
2.741SerLeu: 2.741 ± 1.5
0.548SerMet: 0.548 ± 0.428
1.096SerAsn: 1.096 ± 0.642
3.289SerPro: 3.289 ± 0.938
5.482SerGln: 5.482 ± 1.214
0.548SerArg: 0.548 ± 0.548
6.031SerSer: 6.031 ± 0.934
4.386SerThr: 4.386 ± 1.252
7.127SerVal: 7.127 ± 1.531
0.548SerTrp: 0.548 ± 0.428
0.548SerTyr: 0.548 ± 0.448
0.0SerXaa: 0.0 ± 0.0
Thr
9.32ThrAla: 9.32 ± 1.493
3.289ThrCys: 3.289 ± 1.753
0.548ThrAsp: 0.548 ± 0.428
2.741ThrGlu: 2.741 ± 0.855
4.386ThrPhe: 4.386 ± 0.878
3.838ThrGly: 3.838 ± 1.666
2.741ThrHis: 2.741 ± 0.826
2.193ThrIle: 2.193 ± 0.981
2.741ThrLys: 2.741 ± 1.419
3.838ThrLeu: 3.838 ± 1.44
0.548ThrMet: 0.548 ± 0.411
0.548ThrAsn: 0.548 ± 0.428
3.289ThrPro: 3.289 ± 0.855
5.482ThrGln: 5.482 ± 1.309
1.096ThrArg: 1.096 ± 1.096
3.838ThrSer: 3.838 ± 1.272
3.838ThrThr: 3.838 ± 1.188
1.645ThrVal: 1.645 ± 1.08
0.0ThrTrp: 0.0 ± 0.0
4.386ThrTyr: 4.386 ± 1.373
0.0ThrXaa: 0.0 ± 0.0
Val
7.675ValAla: 7.675 ± 3.075
1.096ValCys: 1.096 ± 0.857
2.193ValAsp: 2.193 ± 0.512
2.193ValGlu: 2.193 ± 0.866
2.741ValPhe: 2.741 ± 1.057
8.224ValGly: 8.224 ± 1.372
1.645ValHis: 1.645 ± 0.538
4.386ValIle: 4.386 ± 0.938
1.096ValLys: 1.096 ± 0.896
3.838ValLeu: 3.838 ± 1.794
2.741ValMet: 2.741 ± 1.363
0.548ValAsn: 0.548 ± 0.448
4.386ValPro: 4.386 ± 0.914
2.741ValGln: 2.741 ± 0.683
4.934ValArg: 4.934 ± 0.969
4.386ValSer: 4.386 ± 1.001
3.838ValThr: 3.838 ± 0.698
5.482ValVal: 5.482 ± 1.082
2.193ValTrp: 2.193 ± 0.871
1.096ValTyr: 1.096 ± 0.581
0.0ValXaa: 0.0 ± 0.0
Trp
1.645TrpAla: 1.645 ± 0.861
1.645TrpCys: 1.645 ± 1.138
0.548TrpAsp: 0.548 ± 0.428
0.0TrpGlu: 0.0 ± 0.0
2.193TrpPhe: 2.193 ± 1.194
1.096TrpGly: 1.096 ± 0.841
0.0TrpHis: 0.0 ± 0.0
3.289TrpIle: 3.289 ± 1.436
3.289TrpLys: 3.289 ± 1.901
0.548TrpLeu: 0.548 ± 0.63
0.548TrpMet: 0.548 ± 0.623
1.096TrpAsn: 1.096 ± 0.634
3.289TrpPro: 3.289 ± 1.111
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.548TrpSer: 0.548 ± 0.682
1.645TrpThr: 1.645 ± 0.625
2.741TrpVal: 2.741 ± 1.205
2.741TrpTrp: 2.741 ± 1.205
0.548TrpTyr: 0.548 ± 0.548
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.741TyrAla: 2.741 ± 0.722
0.0TyrCys: 0.0 ± 0.0
2.193TyrAsp: 2.193 ± 1.274
0.548TyrGlu: 0.548 ± 0.448
3.289TyrPhe: 3.289 ± 1.274
2.741TyrGly: 2.741 ± 1.285
1.096TyrHis: 1.096 ± 0.634
0.548TyrIle: 0.548 ± 0.635
1.096TyrLys: 1.096 ± 0.612
1.096TyrLeu: 1.096 ± 0.634
0.0TyrMet: 0.0 ± 0.0
1.096TyrAsn: 1.096 ± 0.642
1.096TyrPro: 1.096 ± 0.857
0.0TyrGln: 0.0 ± 0.0
1.096TyrArg: 1.096 ± 0.581
2.193TyrSer: 2.193 ± 1.283
1.096TyrThr: 1.096 ± 0.857
3.838TyrVal: 3.838 ± 0.626
0.0TyrTrp: 0.0 ± 0.0
0.548TyrTyr: 0.548 ± 0.428
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 10 proteins (1825 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski