Amino acid dipepetide frequency for Bos taurus papillomavirus 4 (Bovine papillomavirus 4)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.797AlaAla: 5.797 ± 1.624
2.484AlaCys: 2.484 ± 1.188
1.656AlaAsp: 1.656 ± 1.145
3.727AlaGlu: 3.727 ± 1.416
2.484AlaPhe: 2.484 ± 0.842
2.484AlaGly: 2.484 ± 0.773
0.828AlaHis: 0.828 ± 0.589
1.656AlaIle: 1.656 ± 1.441
2.899AlaLys: 2.899 ± 0.891
5.797AlaLeu: 5.797 ± 1.378
0.414AlaMet: 0.414 ± 0.668
1.656AlaAsn: 1.656 ± 0.833
3.727AlaPro: 3.727 ± 0.732
2.899AlaGln: 2.899 ± 0.574
3.727AlaArg: 3.727 ± 1.228
4.141AlaSer: 4.141 ± 0.961
4.969AlaThr: 4.969 ± 1.016
3.727AlaVal: 3.727 ± 0.803
0.414AlaTrp: 0.414 ± 0.423
3.727AlaTyr: 3.727 ± 0.989
0.0AlaXaa: 0.0 ± 0.0
Cys
1.656CysAla: 1.656 ± 0.869
1.656CysCys: 1.656 ± 0.869
1.242CysAsp: 1.242 ± 0.6
1.242CysGlu: 1.242 ± 0.892
1.656CysPhe: 1.656 ± 0.739
0.414CysGly: 0.414 ± 0.315
0.0CysHis: 0.0 ± 0.0
2.07CysIle: 2.07 ± 0.932
1.242CysLys: 1.242 ± 0.628
2.484CysLeu: 2.484 ± 1.369
1.242CysMet: 1.242 ± 0.38
1.242CysAsn: 1.242 ± 0.666
2.484CysPro: 2.484 ± 0.538
0.0CysGln: 0.0 ± 0.0
1.656CysArg: 1.656 ± 0.545
1.656CysSer: 1.656 ± 0.631
2.07CysThr: 2.07 ± 1.233
0.828CysVal: 0.828 ± 0.519
0.828CysTrp: 0.828 ± 0.496
0.828CysTyr: 0.828 ± 0.72
0.0CysXaa: 0.0 ± 0.0
Asp
4.555AspAla: 4.555 ± 1.163
1.242AspCys: 1.242 ± 0.371
4.969AspAsp: 4.969 ± 1.302
4.555AspGlu: 4.555 ± 1.164
2.484AspPhe: 2.484 ± 0.882
2.899AspGly: 2.899 ± 0.786
2.07AspHis: 2.07 ± 0.819
4.969AspIle: 4.969 ± 1.345
1.656AspLys: 1.656 ± 0.61
4.969AspLeu: 4.969 ± 0.81
1.656AspMet: 1.656 ± 0.694
3.313AspAsn: 3.313 ± 1.156
5.797AspPro: 5.797 ± 1.336
2.484AspGln: 2.484 ± 1.17
2.484AspArg: 2.484 ± 1.004
3.313AspSer: 3.313 ± 0.941
3.727AspThr: 3.727 ± 1.085
0.414AspVal: 0.414 ± 0.325
0.828AspTrp: 0.828 ± 0.63
0.414AspTyr: 0.414 ± 0.351
0.0AspXaa: 0.0 ± 0.0
Glu
2.07GluAla: 2.07 ± 1.288
0.828GluCys: 0.828 ± 0.63
6.211GluAsp: 6.211 ± 1.265
5.383GluGlu: 5.383 ± 1.582
2.484GluPhe: 2.484 ± 0.592
4.141GluGly: 4.141 ± 1.325
1.656GluHis: 1.656 ± 0.449
2.899GluIle: 2.899 ± 1.136
1.656GluLys: 1.656 ± 0.704
2.899GluLeu: 2.899 ± 0.876
1.242GluMet: 1.242 ± 0.584
3.727GluAsn: 3.727 ± 1.129
2.07GluPro: 2.07 ± 0.778
2.484GluGln: 2.484 ± 0.783
1.656GluArg: 1.656 ± 0.749
3.727GluSer: 3.727 ± 0.835
4.555GluThr: 4.555 ± 1.279
3.313GluVal: 3.313 ± 1.365
0.414GluTrp: 0.414 ± 0.325
0.828GluTyr: 0.828 ± 0.586
0.0GluXaa: 0.0 ± 0.0
Phe
2.899PheAla: 2.899 ± 1.222
0.828PheCys: 0.828 ± 0.659
2.07PheAsp: 2.07 ± 0.807
2.484PheGlu: 2.484 ± 0.63
1.242PhePhe: 1.242 ± 0.48
1.656PheGly: 1.656 ± 0.826
0.414PheHis: 0.414 ± 0.315
2.484PheIle: 2.484 ± 0.95
2.899PheLys: 2.899 ± 1.052
7.039PheLeu: 7.039 ± 0.869
0.828PheMet: 0.828 ± 0.63
1.242PheAsn: 1.242 ± 0.64
2.07PhePro: 2.07 ± 0.911
3.313PheGln: 3.313 ± 0.961
2.484PheArg: 2.484 ± 0.787
2.07PheSer: 2.07 ± 0.645
2.07PheThr: 2.07 ± 0.727
3.313PheVal: 3.313 ± 0.904
2.484PheTrp: 2.484 ± 0.921
2.484PheTyr: 2.484 ± 0.926
0.0PheXaa: 0.0 ± 0.0
Gly
4.141GlyAla: 4.141 ± 1.212
0.828GlyCys: 0.828 ± 0.449
4.555GlyAsp: 4.555 ± 1.213
2.484GlyGlu: 2.484 ± 0.814
1.656GlyPhe: 1.656 ± 0.555
4.555GlyGly: 4.555 ± 2.197
2.899GlyHis: 2.899 ± 1.013
2.07GlyIle: 2.07 ± 0.745
2.899GlyLys: 2.899 ± 0.944
1.656GlyLeu: 1.656 ± 0.579
0.828GlyMet: 0.828 ± 0.46
2.899GlyAsn: 2.899 ± 0.932
3.727GlyPro: 3.727 ± 0.775
4.141GlyGln: 4.141 ± 1.482
5.797GlyArg: 5.797 ± 2.369
5.383GlySer: 5.383 ± 1.219
5.797GlyThr: 5.797 ± 1.154
4.141GlyVal: 4.141 ± 1.008
0.0GlyTrp: 0.0 ± 0.0
2.07GlyTyr: 2.07 ± 0.679
0.0GlyXaa: 0.0 ± 0.0
His
0.828HisAla: 0.828 ± 0.57
0.828HisCys: 0.828 ± 0.626
1.242HisAsp: 1.242 ± 0.804
0.0HisGlu: 0.0 ± 0.0
0.828HisPhe: 0.828 ± 0.369
0.828HisGly: 0.828 ± 0.517
0.0HisHis: 0.0 ± 0.0
0.828HisIle: 0.828 ± 0.545
2.07HisLys: 2.07 ± 1.111
1.656HisLeu: 1.656 ± 0.59
0.0HisMet: 0.0 ± 0.0
1.242HisAsn: 1.242 ± 0.371
2.484HisPro: 2.484 ± 0.874
0.828HisGln: 0.828 ± 0.489
2.07HisArg: 2.07 ± 0.582
1.656HisSer: 1.656 ± 0.524
1.242HisThr: 1.242 ± 0.6
1.242HisVal: 1.242 ± 0.38
0.414HisTrp: 0.414 ± 0.325
1.242HisTyr: 1.242 ± 0.6
0.0HisXaa: 0.0 ± 0.0
Ile
3.727IleAla: 3.727 ± 1.127
2.899IleCys: 2.899 ± 1.201
2.484IleAsp: 2.484 ± 0.8
4.555IleGlu: 4.555 ± 1.067
2.899IlePhe: 2.899 ± 0.676
2.07IleGly: 2.07 ± 0.598
0.414IleHis: 0.414 ± 0.435
1.242IleIle: 1.242 ± 0.576
1.656IleLys: 1.656 ± 0.922
4.141IleLeu: 4.141 ± 1.745
0.828IleMet: 0.828 ± 0.553
0.414IleAsn: 0.414 ± 0.435
0.828IlePro: 0.828 ± 0.449
2.07IleGln: 2.07 ± 0.942
0.828IleArg: 0.828 ± 0.645
3.727IleSer: 3.727 ± 1.268
2.899IleThr: 2.899 ± 1.1
3.727IleVal: 3.727 ± 1.312
0.0IleTrp: 0.0 ± 0.0
2.07IleTyr: 2.07 ± 0.94
0.0IleXaa: 0.0 ± 0.0
Lys
3.313LysAla: 3.313 ± 1.017
2.07LysCys: 2.07 ± 0.931
2.07LysAsp: 2.07 ± 0.711
3.313LysGlu: 3.313 ± 0.868
5.383LysPhe: 5.383 ± 1.815
3.727LysGly: 3.727 ± 1.21
1.656LysHis: 1.656 ± 0.522
1.656LysIle: 1.656 ± 0.319
2.484LysLys: 2.484 ± 0.901
2.899LysLeu: 2.899 ± 0.69
0.828LysMet: 0.828 ± 0.414
2.07LysAsn: 2.07 ± 0.598
0.828LysPro: 0.828 ± 0.496
2.484LysGln: 2.484 ± 0.702
4.969LysArg: 4.969 ± 0.926
3.313LysSer: 3.313 ± 1.334
4.555LysThr: 4.555 ± 0.775
1.242LysVal: 1.242 ± 0.59
1.242LysTrp: 1.242 ± 0.471
1.242LysTyr: 1.242 ± 0.371
0.0LysXaa: 0.0 ± 0.0
Leu
3.727LeuAla: 3.727 ± 0.813
2.899LeuCys: 2.899 ± 1.136
6.211LeuAsp: 6.211 ± 1.35
5.383LeuGlu: 5.383 ± 1.74
4.555LeuPhe: 4.555 ± 1.47
3.313LeuGly: 3.313 ± 1.499
2.07LeuHis: 2.07 ± 0.538
4.555LeuIle: 4.555 ± 1.241
6.211LeuLys: 6.211 ± 1.03
11.18LeuLeu: 11.18 ± 3.175
1.656LeuMet: 1.656 ± 0.582
2.484LeuAsn: 2.484 ± 0.719
5.383LeuPro: 5.383 ± 1.423
6.625LeuGln: 6.625 ± 1.967
5.383LeuArg: 5.383 ± 2.013
5.383LeuSer: 5.383 ± 1.232
3.727LeuThr: 3.727 ± 1.326
4.141LeuVal: 4.141 ± 1.167
2.484LeuTrp: 2.484 ± 0.849
2.484LeuTyr: 2.484 ± 1.242
0.0LeuXaa: 0.0 ± 0.0
Met
0.828MetAla: 0.828 ± 0.576
0.828MetCys: 0.828 ± 0.65
0.828MetAsp: 0.828 ± 0.352
0.0MetGlu: 0.0 ± 0.0
0.828MetPhe: 0.828 ± 0.352
2.07MetGly: 2.07 ± 0.478
0.0MetHis: 0.0 ± 0.0
0.828MetIle: 0.828 ± 0.545
1.242MetLys: 1.242 ± 0.698
0.828MetLeu: 0.828 ± 0.369
0.0MetMet: 0.0 ± 0.0
1.242MetAsn: 1.242 ± 0.715
0.828MetPro: 0.828 ± 0.593
1.656MetGln: 1.656 ± 0.694
0.0MetArg: 0.0 ± 0.0
3.313MetSer: 3.313 ± 0.823
0.828MetThr: 0.828 ± 0.63
2.07MetVal: 2.07 ± 0.72
0.414MetTrp: 0.414 ± 0.489
0.828MetTyr: 0.828 ± 0.46
0.0MetXaa: 0.0 ± 0.0
Asn
2.484AsnAla: 2.484 ± 1.07
1.242AsnCys: 1.242 ± 0.59
2.07AsnAsp: 2.07 ± 0.714
1.242AsnGlu: 1.242 ± 0.6
2.899AsnPhe: 2.899 ± 1.32
3.313AsnGly: 3.313 ± 0.778
0.414AsnHis: 0.414 ± 0.489
0.0AsnIle: 0.0 ± 0.0
2.484AsnLys: 2.484 ± 0.956
2.899AsnLeu: 2.899 ± 1.365
0.828AsnMet: 0.828 ± 0.65
1.656AsnAsn: 1.656 ± 0.704
2.07AsnPro: 2.07 ± 0.708
2.899AsnGln: 2.899 ± 0.786
1.656AsnArg: 1.656 ± 0.835
4.141AsnSer: 4.141 ± 1.12
4.555AsnThr: 4.555 ± 0.574
3.727AsnVal: 3.727 ± 0.967
0.828AsnTrp: 0.828 ± 0.352
0.828AsnTyr: 0.828 ± 0.52
0.0AsnXaa: 0.0 ± 0.0
Pro
3.727ProAla: 3.727 ± 1.213
0.828ProCys: 0.828 ± 0.553
2.899ProAsp: 2.899 ± 1.005
5.383ProGlu: 5.383 ± 1.472
2.07ProPhe: 2.07 ± 0.767
4.555ProGly: 4.555 ± 1.808
1.242ProHis: 1.242 ± 0.834
2.899ProIle: 2.899 ± 1.299
4.969ProLys: 4.969 ± 1.404
6.211ProLeu: 6.211 ± 1.05
0.414ProMet: 0.414 ± 0.363
2.899ProAsn: 2.899 ± 0.972
7.867ProPro: 7.867 ± 1.102
1.242ProGln: 1.242 ± 0.764
2.07ProArg: 2.07 ± 0.787
4.141ProSer: 4.141 ± 1.456
4.141ProThr: 4.141 ± 1.741
3.727ProVal: 3.727 ± 1.037
0.414ProTrp: 0.414 ± 0.469
1.656ProTyr: 1.656 ± 1.3
0.0ProXaa: 0.0 ± 0.0
Gln
2.899GlnAla: 2.899 ± 0.574
0.828GlnCys: 0.828 ± 0.586
3.727GlnAsp: 3.727 ± 1.029
0.828GlnGlu: 0.828 ± 0.553
1.656GlnPhe: 1.656 ± 0.695
3.727GlnGly: 3.727 ± 1.028
2.07GlnHis: 2.07 ± 0.595
2.484GlnIle: 2.484 ± 1.057
1.242GlnLys: 1.242 ± 0.38
4.555GlnLeu: 4.555 ± 1.124
1.242GlnMet: 1.242 ± 0.6
2.07GlnAsn: 2.07 ± 0.64
2.899GlnPro: 2.899 ± 0.961
3.313GlnGln: 3.313 ± 0.682
4.969GlnArg: 4.969 ± 1.28
2.484GlnSer: 2.484 ± 1.182
1.242GlnThr: 1.242 ± 0.536
4.555GlnVal: 4.555 ± 0.812
1.656GlnTrp: 1.656 ± 0.777
1.242GlnTyr: 1.242 ± 1.23
0.0GlnXaa: 0.0 ± 0.0
Arg
4.555ArgAla: 4.555 ± 0.998
2.07ArgCys: 2.07 ± 0.656
2.07ArgAsp: 2.07 ± 1.385
2.899ArgGlu: 2.899 ± 0.69
1.656ArgPhe: 1.656 ± 0.91
7.039ArgGly: 7.039 ± 2.24
1.656ArgHis: 1.656 ± 0.966
1.242ArgIle: 1.242 ± 0.628
2.484ArgLys: 2.484 ± 1.054
8.696ArgLeu: 8.696 ± 2.003
1.656ArgMet: 1.656 ± 1.157
3.727ArgAsn: 3.727 ± 1.366
4.141ArgPro: 4.141 ± 1.338
2.07ArgGln: 2.07 ± 0.905
7.039ArgArg: 7.039 ± 1.295
6.625ArgSer: 6.625 ± 2.332
1.656ArgThr: 1.656 ± 0.971
3.313ArgVal: 3.313 ± 0.824
0.828ArgTrp: 0.828 ± 0.544
0.414ArgTyr: 0.414 ± 0.315
0.0ArgXaa: 0.0 ± 0.0
Ser
4.141SerAla: 4.141 ± 0.893
0.414SerCys: 0.414 ± 0.469
3.313SerAsp: 3.313 ± 0.584
2.899SerGlu: 2.899 ± 1.055
5.383SerPhe: 5.383 ± 1.43
4.969SerGly: 4.969 ± 1.223
0.828SerHis: 0.828 ± 0.63
2.07SerIle: 2.07 ± 0.965
2.899SerLys: 2.899 ± 0.57
9.11SerLeu: 9.11 ± 1.123
2.07SerMet: 2.07 ± 0.61
2.899SerAsn: 2.899 ± 0.891
4.141SerPro: 4.141 ± 1.792
2.484SerGln: 2.484 ± 0.783
8.282SerArg: 8.282 ± 2.502
6.625SerSer: 6.625 ± 2.989
5.797SerThr: 5.797 ± 1.515
3.727SerVal: 3.727 ± 0.866
0.828SerTrp: 0.828 ± 0.369
0.414SerTyr: 0.414 ± 0.489
0.0SerXaa: 0.0 ± 0.0
Thr
3.313ThrAla: 3.313 ± 0.974
1.242ThrCys: 1.242 ± 0.698
2.899ThrAsp: 2.899 ± 1.473
3.727ThrGlu: 3.727 ± 1.133
2.07ThrPhe: 2.07 ± 0.388
4.969ThrGly: 4.969 ± 1.228
0.828ThrHis: 0.828 ± 0.423
3.727ThrIle: 3.727 ± 1.583
3.313ThrLys: 3.313 ± 0.824
4.555ThrLeu: 4.555 ± 1.881
1.242ThrMet: 1.242 ± 0.725
1.656ThrAsn: 1.656 ± 0.555
6.625ThrPro: 6.625 ± 1.642
4.141ThrGln: 4.141 ± 1.052
4.969ThrArg: 4.969 ± 0.794
7.453ThrSer: 7.453 ± 1.918
4.141ThrThr: 4.141 ± 0.99
3.313ThrVal: 3.313 ± 0.815
1.242ThrTrp: 1.242 ± 0.648
1.656ThrTyr: 1.656 ± 0.668
0.0ThrXaa: 0.0 ± 0.0
Val
1.656ValAla: 1.656 ± 0.694
1.656ValCys: 1.656 ± 0.668
5.383ValAsp: 5.383 ± 0.565
0.828ValGlu: 0.828 ± 0.352
2.07ValPhe: 2.07 ± 0.659
3.727ValGly: 3.727 ± 1.036
1.242ValHis: 1.242 ± 0.501
2.899ValIle: 2.899 ± 1.063
3.313ValLys: 3.313 ± 0.772
4.141ValLeu: 4.141 ± 1.033
1.656ValMet: 1.656 ± 0.888
2.899ValAsn: 2.899 ± 0.783
4.555ValPro: 4.555 ± 1.903
2.899ValGln: 2.899 ± 0.93
4.141ValArg: 4.141 ± 1.731
2.899ValSer: 2.899 ± 0.86
4.969ValThr: 4.969 ± 1.713
2.07ValVal: 2.07 ± 0.959
0.828ValTrp: 0.828 ± 0.543
3.313ValTyr: 3.313 ± 0.93
0.0ValXaa: 0.0 ± 0.0
Trp
1.656TrpAla: 1.656 ± 0.641
0.414TrpCys: 0.414 ± 0.461
1.242TrpAsp: 1.242 ± 0.975
1.242TrpGlu: 1.242 ± 0.661
0.0TrpPhe: 0.0 ± 0.0
0.828TrpGly: 0.828 ± 0.506
0.414TrpHis: 0.414 ± 0.351
1.242TrpIle: 1.242 ± 0.584
2.484TrpLys: 2.484 ± 1.081
0.828TrpLeu: 0.828 ± 0.52
0.414TrpMet: 0.414 ± 0.461
1.242TrpAsn: 1.242 ± 0.696
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.414TrpSer: 0.414 ± 0.351
2.07TrpThr: 2.07 ± 0.836
1.656TrpVal: 1.656 ± 0.319
0.414TrpTrp: 0.414 ± 0.315
0.414TrpTyr: 0.414 ± 0.489
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.656TyrAla: 1.656 ± 0.611
0.414TyrCys: 0.414 ± 0.461
1.656TyrAsp: 1.656 ± 0.975
2.07TyrGlu: 2.07 ± 0.964
2.07TyrPhe: 2.07 ± 0.602
1.242TyrGly: 1.242 ± 0.584
0.828TyrHis: 0.828 ± 0.352
1.656TyrIle: 1.656 ± 0.606
1.242TyrLys: 1.242 ± 0.532
3.313TyrLeu: 3.313 ± 0.913
0.0TyrMet: 0.0 ± 0.0
1.656TyrAsn: 1.656 ± 0.555
0.828TyrPro: 0.828 ± 0.553
1.656TyrGln: 1.656 ± 1.28
1.656TyrArg: 1.656 ± 0.449
0.828TyrSer: 0.828 ± 0.544
2.07TyrThr: 2.07 ± 0.42
2.899TyrVal: 2.899 ± 1.132
0.414TyrTrp: 0.414 ± 0.535
2.899TyrTyr: 2.899 ± 1.48
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 11 proteins (2416 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski