Amino acid dipepetide frequency for Hansschlegelia quercus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
20.844AlaAla: 20.844 ± 0.234
1.089AlaCys: 1.089 ± 0.036
7.347AlaAsp: 7.347 ± 0.099
8.871AlaGlu: 8.871 ± 0.107
5.085AlaPhe: 5.085 ± 0.075
11.584AlaGly: 11.584 ± 0.122
2.289AlaHis: 2.289 ± 0.045
6.786AlaIle: 6.786 ± 0.081
4.633AlaLys: 4.633 ± 0.072
15.486AlaLeu: 15.486 ± 0.156
3.39AlaMet: 3.39 ± 0.056
2.784AlaAsn: 2.784 ± 0.058
7.145AlaPro: 7.145 ± 0.108
3.791AlaGln: 3.791 ± 0.074
10.236AlaArg: 10.236 ± 0.135
7.415AlaSer: 7.415 ± 0.098
6.723AlaThr: 6.723 ± 0.092
9.486AlaVal: 9.486 ± 0.11
1.49AlaTrp: 1.49 ± 0.042
2.66AlaTyr: 2.66 ± 0.05
0.0AlaXaa: 0.0 ± 0.0
Cys
0.968CysAla: 0.968 ± 0.029
0.095CysCys: 0.095 ± 0.01
0.438CysAsp: 0.438 ± 0.021
0.451CysGlu: 0.451 ± 0.022
0.286CysPhe: 0.286 ± 0.015
0.929CysGly: 0.929 ± 0.029
0.163CysHis: 0.163 ± 0.011
0.297CysIle: 0.297 ± 0.018
0.147CysLys: 0.147 ± 0.013
0.661CysLeu: 0.661 ± 0.024
0.144CysMet: 0.144 ± 0.013
0.124CysAsn: 0.124 ± 0.011
0.376CysPro: 0.376 ± 0.019
0.161CysGln: 0.161 ± 0.013
0.558CysArg: 0.558 ± 0.022
0.414CysSer: 0.414 ± 0.021
0.29CysThr: 0.29 ± 0.018
0.629CysVal: 0.629 ± 0.023
0.104CysTrp: 0.104 ± 0.01
0.152CysTyr: 0.152 ± 0.013
0.0CysXaa: 0.0 ± 0.0
Asp
7.886AspAla: 7.886 ± 0.092
0.414AspCys: 0.414 ± 0.023
3.289AspAsp: 3.289 ± 0.068
3.854AspGlu: 3.854 ± 0.065
2.035AspPhe: 2.035 ± 0.045
5.738AspGly: 5.738 ± 0.076
1.194AspHis: 1.194 ± 0.037
2.456AspIle: 2.456 ± 0.05
1.675AspLys: 1.675 ± 0.046
6.07AspLeu: 6.07 ± 0.086
1.183AspMet: 1.183 ± 0.031
0.976AspAsn: 0.976 ± 0.033
3.603AspPro: 3.603 ± 0.066
1.5AspGln: 1.5 ± 0.043
4.727AspArg: 4.727 ± 0.078
2.007AspSer: 2.007 ± 0.044
2.134AspThr: 2.134 ± 0.053
4.797AspVal: 4.797 ± 0.07
0.889AspTrp: 0.889 ± 0.031
1.384AspTyr: 1.384 ± 0.037
0.0AspXaa: 0.0 ± 0.0
Glu
8.972GluAla: 8.972 ± 0.102
0.313GluCys: 0.313 ± 0.016
2.957GluAsp: 2.957 ± 0.059
3.261GluGlu: 3.261 ± 0.058
1.616GluPhe: 1.616 ± 0.041
4.767GluGly: 4.767 ± 0.066
1.126GluHis: 1.126 ± 0.031
3.718GluIle: 3.718 ± 0.064
2.234GluLys: 2.234 ± 0.061
5.387GluLeu: 5.387 ± 0.076
1.375GluMet: 1.375 ± 0.035
1.439GluAsn: 1.439 ± 0.037
3.167GluPro: 3.167 ± 0.062
1.907GluGln: 1.907 ± 0.049
5.601GluArg: 5.601 ± 0.083
2.336GluSer: 2.336 ± 0.048
3.913GluThr: 3.913 ± 0.067
3.938GluVal: 3.938 ± 0.059
0.615GluTrp: 0.615 ± 0.027
0.771GluTyr: 0.771 ± 0.031
0.0GluXaa: 0.0 ± 0.0
Phe
5.182PheAla: 5.182 ± 0.077
0.334PheCys: 0.334 ± 0.019
2.667PheAsp: 2.667 ± 0.051
2.222PheGlu: 2.222 ± 0.049
1.393PhePhe: 1.393 ± 0.043
3.872PheGly: 3.872 ± 0.057
0.657PheHis: 0.657 ± 0.029
1.411PheIle: 1.411 ± 0.042
1.011PheLys: 1.011 ± 0.03
3.144PheLeu: 3.144 ± 0.068
0.688PheMet: 0.688 ± 0.027
0.851PheAsn: 0.851 ± 0.027
1.6PhePro: 1.6 ± 0.039
0.863PheGln: 0.863 ± 0.029
2.397PheArg: 2.397 ± 0.048
2.092PheSer: 2.092 ± 0.039
1.716PheThr: 1.716 ± 0.038
3.142PheVal: 3.142 ± 0.055
0.535PheTrp: 0.535 ± 0.026
0.821PheTyr: 0.821 ± 0.03
0.0PheXaa: 0.0 ± 0.0
Gly
11.676GlyAla: 11.676 ± 0.124
0.793GlyCys: 0.793 ± 0.027
4.984GlyAsp: 4.984 ± 0.08
5.231GlyGlu: 5.231 ± 0.076
3.861GlyPhe: 3.861 ± 0.065
8.181GlyGly: 8.181 ± 0.133
1.756GlyHis: 1.756 ± 0.046
3.301GlyIle: 3.301 ± 0.06
3.027GlyLys: 3.027 ± 0.064
9.296GlyLeu: 9.296 ± 0.099
2.064GlyMet: 2.064 ± 0.039
1.423GlyAsn: 1.423 ± 0.041
4.128GlyPro: 4.128 ± 0.069
2.533GlyGln: 2.533 ± 0.05
7.163GlyArg: 7.163 ± 0.09
4.833GlySer: 4.833 ± 0.085
3.405GlyThr: 3.405 ± 0.06
7.864GlyVal: 7.864 ± 0.075
1.348GlyTrp: 1.348 ± 0.039
2.158GlyTyr: 2.158 ± 0.052
0.0GlyXaa: 0.0 ± 0.0
His
2.31HisAla: 2.31 ± 0.051
0.162HisCys: 0.162 ± 0.013
1.156HisAsp: 1.156 ± 0.035
0.961HisGlu: 0.961 ± 0.031
0.72HisPhe: 0.72 ± 0.027
1.846HisGly: 1.846 ± 0.039
0.484HisHis: 0.484 ± 0.025
0.748HisIle: 0.748 ± 0.027
0.398HisLys: 0.398 ± 0.019
1.762HisLeu: 1.762 ± 0.043
0.412HisMet: 0.412 ± 0.021
0.36HisAsn: 0.36 ± 0.02
1.18HisPro: 1.18 ± 0.035
0.439HisGln: 0.439 ± 0.02
1.229HisArg: 1.229 ± 0.036
0.792HisSer: 0.792 ± 0.025
0.654HisThr: 0.654 ± 0.024
1.575HisVal: 1.575 ± 0.039
0.242HisTrp: 0.242 ± 0.016
0.467HisTyr: 0.467 ± 0.022
0.0HisXaa: 0.0 ± 0.0
Ile
7.439IleAla: 7.439 ± 0.096
0.437IleCys: 0.437 ± 0.021
3.441IleAsp: 3.441 ± 0.065
3.532IleGlu: 3.532 ± 0.057
1.457IlePhe: 1.457 ± 0.037
4.785IleGly: 4.785 ± 0.065
0.81IleHis: 0.81 ± 0.026
1.628IleIle: 1.628 ± 0.043
1.245IleLys: 1.245 ± 0.034
3.804IleLeu: 3.804 ± 0.072
0.814IleMet: 0.814 ± 0.032
0.999IleAsn: 0.999 ± 0.03
1.985IlePro: 1.985 ± 0.045
0.99IleGln: 0.99 ± 0.032
3.068IleArg: 3.068 ± 0.051
2.402IleSer: 2.402 ± 0.057
2.077IleThr: 2.077 ± 0.043
4.561IleVal: 4.561 ± 0.076
0.491IleTrp: 0.491 ± 0.024
0.971IleTyr: 0.971 ± 0.029
0.0IleXaa: 0.0 ± 0.0
Lys
4.608LysAla: 4.608 ± 0.067
0.123LysCys: 0.123 ± 0.009
1.707LysAsp: 1.707 ± 0.043
1.559LysGlu: 1.559 ± 0.047
0.857LysPhe: 0.857 ± 0.03
2.673LysGly: 2.673 ± 0.057
0.492LysHis: 0.492 ± 0.023
1.677LysIle: 1.677 ± 0.045
1.25LysLys: 1.25 ± 0.043
3.388LysLeu: 3.388 ± 0.057
0.677LysMet: 0.677 ± 0.024
0.799LysAsn: 0.799 ± 0.029
2.223LysPro: 2.223 ± 0.047
0.842LysGln: 0.842 ± 0.03
2.615LysArg: 2.615 ± 0.053
1.782LysSer: 1.782 ± 0.047
2.056LysThr: 2.056 ± 0.048
2.413LysVal: 2.413 ± 0.052
0.312LysTrp: 0.312 ± 0.019
0.542LysTyr: 0.542 ± 0.025
0.0LysXaa: 0.0 ± 0.0
Leu
14.953LeuAla: 14.953 ± 0.155
0.739LeuCys: 0.739 ± 0.028
6.328LeuAsp: 6.328 ± 0.087
5.169LeuGlu: 5.169 ± 0.079
3.504LeuPhe: 3.504 ± 0.066
8.954LeuGly: 8.954 ± 0.098
1.645LeuHis: 1.645 ± 0.041
4.766LeuIle: 4.766 ± 0.084
3.979LeuLys: 3.979 ± 0.066
8.925LeuLeu: 8.925 ± 0.115
2.061LeuMet: 2.061 ± 0.042
2.254LeuAsn: 2.254 ± 0.053
5.242LeuPro: 5.242 ± 0.076
2.245LeuGln: 2.245 ± 0.052
6.756LeuArg: 6.756 ± 0.091
6.238LeuSer: 6.238 ± 0.074
5.454LeuThr: 5.454 ± 0.079
7.875LeuVal: 7.875 ± 0.107
1.116LeuTrp: 1.116 ± 0.037
1.878LeuTyr: 1.878 ± 0.04
0.0LeuXaa: 0.0 ± 0.0
Met
2.919MetAla: 2.919 ± 0.056
0.125MetCys: 0.125 ± 0.011
0.957MetAsp: 0.957 ± 0.032
0.973MetGlu: 0.973 ± 0.03
0.632MetPhe: 0.632 ± 0.024
1.63MetGly: 1.63 ± 0.042
0.331MetHis: 0.331 ± 0.02
1.195MetIle: 1.195 ± 0.038
0.864MetLys: 0.864 ± 0.032
2.226MetLeu: 2.226 ± 0.051
0.514MetMet: 0.514 ± 0.024
0.627MetAsn: 0.627 ± 0.021
1.303MetPro: 1.303 ± 0.036
0.576MetGln: 0.576 ± 0.019
1.779MetArg: 1.779 ± 0.04
1.602MetSer: 1.602 ± 0.036
1.768MetThr: 1.768 ± 0.041
1.396MetVal: 1.396 ± 0.04
0.187MetTrp: 0.187 ± 0.012
0.233MetTyr: 0.233 ± 0.016
0.0MetXaa: 0.0 ± 0.0
Asn
3.026AsnAla: 3.026 ± 0.056
0.182AsnCys: 0.182 ± 0.012
1.25AsnAsp: 1.25 ± 0.037
1.075AsnGlu: 1.075 ± 0.032
0.824AsnPhe: 0.824 ± 0.032
2.055AsnGly: 2.055 ± 0.043
0.435AsnHis: 0.435 ± 0.02
0.904AsnIle: 0.904 ± 0.031
0.599AsnLys: 0.599 ± 0.024
2.172AsnLeu: 2.172 ± 0.053
0.477AsnMet: 0.477 ± 0.02
0.515AsnAsn: 0.515 ± 0.022
1.482AsnPro: 1.482 ± 0.039
0.573AsnGln: 0.573 ± 0.024
1.546AsnArg: 1.546 ± 0.042
0.891AsnSer: 0.891 ± 0.033
0.897AsnThr: 0.897 ± 0.033
1.954AsnVal: 1.954 ± 0.046
0.357AsnTrp: 0.357 ± 0.019
0.514AsnTyr: 0.514 ± 0.022
0.0AsnXaa: 0.0 ± 0.0
Pro
6.948ProAla: 6.948 ± 0.111
0.304ProCys: 0.304 ± 0.018
3.654ProAsp: 3.654 ± 0.068
3.996ProGlu: 3.996 ± 0.065
2.055ProPhe: 2.055 ± 0.04
4.558ProGly: 4.558 ± 0.071
0.953ProHis: 0.953 ± 0.03
2.326ProIle: 2.326 ± 0.043
1.993ProLys: 1.993 ± 0.044
4.941ProLeu: 4.941 ± 0.072
1.055ProMet: 1.055 ± 0.033
1.283ProAsn: 1.283 ± 0.039
2.71ProPro: 2.71 ± 0.061
1.577ProGln: 1.577 ± 0.042
3.269ProArg: 3.269 ± 0.061
3.083ProSer: 3.083 ± 0.05
2.671ProThr: 2.671 ± 0.055
4.017ProVal: 4.017 ± 0.063
0.664ProTrp: 0.664 ± 0.031
1.155ProTyr: 1.155 ± 0.031
0.0ProXaa: 0.0 ± 0.0
Gln
3.684GlnAla: 3.684 ± 0.066
0.163GlnCys: 0.163 ± 0.011
1.276GlnAsp: 1.276 ± 0.032
1.222GlnGlu: 1.222 ± 0.029
0.924GlnPhe: 0.924 ± 0.032
2.112GlnGly: 2.112 ± 0.047
0.446GlnHis: 0.446 ± 0.02
1.624GlnIle: 1.624 ± 0.044
0.921GlnLys: 0.921 ± 0.033
2.258GlnLeu: 2.258 ± 0.055
0.646GlnMet: 0.646 ± 0.023
0.698GlnAsn: 0.698 ± 0.026
1.58GlnPro: 1.58 ± 0.046
0.852GlnGln: 0.852 ± 0.038
2.019GlnArg: 2.019 ± 0.042
1.589GlnSer: 1.589 ± 0.041
1.581GlnThr: 1.581 ± 0.04
1.825GlnVal: 1.825 ± 0.043
0.284GlnTrp: 0.284 ± 0.016
0.431GlnTyr: 0.431 ± 0.021
0.0GlnXaa: 0.0 ± 0.0
Arg
9.414ArgAla: 9.414 ± 0.113
0.439ArgCys: 0.439 ± 0.019
4.215ArgAsp: 4.215 ± 0.063
4.56ArgGlu: 4.56 ± 0.062
3.072ArgPhe: 3.072 ± 0.062
5.537ArgGly: 5.537 ± 0.07
1.486ArgHis: 1.486 ± 0.036
3.816ArgIle: 3.816 ± 0.064
2.149ArgLys: 2.149 ± 0.041
8.737ArgLeu: 8.737 ± 0.109
1.776ArgMet: 1.776 ± 0.04
1.596ArgAsn: 1.596 ± 0.042
4.159ArgPro: 4.159 ± 0.085
2.026ArgGln: 2.026 ± 0.053
6.752ArgArg: 6.752 ± 0.091
4.105ArgSer: 4.105 ± 0.063
3.477ArgThr: 3.477 ± 0.055
5.259ArgVal: 5.259 ± 0.074
0.99ArgTrp: 0.99 ± 0.027
1.592ArgTyr: 1.592 ± 0.045
0.0ArgXaa: 0.0 ± 0.0
Ser
7.021SerAla: 7.021 ± 0.099
0.367SerCys: 0.367 ± 0.02
2.862SerAsp: 2.862 ± 0.06
3.003SerGlu: 3.003 ± 0.054
2.228SerPhe: 2.228 ± 0.044
5.613SerGly: 5.613 ± 0.083
0.945SerHis: 0.945 ± 0.031
2.503SerIle: 2.503 ± 0.05
1.579SerLys: 1.579 ± 0.037
5.347SerLeu: 5.347 ± 0.076
1.173SerMet: 1.173 ± 0.038
1.208SerAsn: 1.208 ± 0.036
2.93SerPro: 2.93 ± 0.052
1.377SerGln: 1.377 ± 0.042
3.847SerArg: 3.847 ± 0.071
3.144SerSer: 3.144 ± 0.059
2.582SerThr: 2.582 ± 0.056
4.045SerVal: 4.045 ± 0.061
0.677SerTrp: 0.677 ± 0.027
1.21SerTyr: 1.21 ± 0.037
0.0SerXaa: 0.0 ± 0.0
Thr
6.03ThrAla: 6.03 ± 0.081
0.361ThrCys: 0.361 ± 0.017
2.586ThrAsp: 2.586 ± 0.062
2.525ThrGlu: 2.525 ± 0.046
1.909ThrPhe: 1.909 ± 0.05
4.753ThrGly: 4.753 ± 0.077
0.875ThrHis: 0.875 ± 0.032
2.847ThrIle: 2.847 ± 0.056
1.448ThrLys: 1.448 ± 0.035
5.946ThrLeu: 5.946 ± 0.078
0.995ThrMet: 0.995 ± 0.031
1.132ThrAsn: 1.132 ± 0.034
3.504ThrPro: 3.504 ± 0.055
1.163ThrGln: 1.163 ± 0.04
3.274ThrArg: 3.274 ± 0.058
2.577ThrSer: 2.577 ± 0.046
2.691ThrThr: 2.691 ± 0.059
4.209ThrVal: 4.209 ± 0.06
0.565ThrTrp: 0.565 ± 0.027
1.071ThrTyr: 1.071 ± 0.031
0.0ThrXaa: 0.0 ± 0.0
Val
11.365ValAla: 11.365 ± 0.132
0.64ValCys: 0.64 ± 0.027
4.7ValAsp: 4.7 ± 0.063
5.173ValGlu: 5.173 ± 0.081
2.859ValPhe: 2.859 ± 0.058
6.458ValGly: 6.458 ± 0.073
1.239ValHis: 1.239 ± 0.032
3.636ValIle: 3.636 ± 0.066
2.454ValLys: 2.454 ± 0.054
7.01ValLeu: 7.01 ± 0.091
1.757ValMet: 1.757 ± 0.044
1.824ValAsn: 1.824 ± 0.042
3.284ValPro: 3.284 ± 0.059
1.811ValGln: 1.811 ± 0.047
5.393ValArg: 5.393 ± 0.076
4.532ValSer: 4.532 ± 0.069
4.753ValThr: 4.753 ± 0.062
6.926ValVal: 6.926 ± 0.105
0.971ValTrp: 0.971 ± 0.029
1.526ValTyr: 1.526 ± 0.037
0.0ValXaa: 0.0 ± 0.0
Trp
1.288TrpAla: 1.288 ± 0.034
0.11TrpCys: 0.11 ± 0.011
0.553TrpAsp: 0.553 ± 0.026
0.518TrpGlu: 0.518 ± 0.023
0.508TrpPhe: 0.508 ± 0.022
0.883TrpGly: 0.883 ± 0.031
0.211TrpHis: 0.211 ± 0.015
0.637TrpIle: 0.637 ± 0.025
0.392TrpLys: 0.392 ± 0.017
1.475TrpLeu: 1.475 ± 0.043
0.298TrpMet: 0.298 ± 0.019
0.365TrpAsn: 0.365 ± 0.021
0.665TrpPro: 0.665 ± 0.025
0.338TrpGln: 0.338 ± 0.02
1.346TrpArg: 1.346 ± 0.036
0.839TrpSer: 0.839 ± 0.03
0.815TrpThr: 0.815 ± 0.032
0.681TrpVal: 0.681 ± 0.027
0.202TrpTrp: 0.202 ± 0.013
0.226TrpTyr: 0.226 ± 0.014
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.602TyrAla: 2.602 ± 0.054
0.198TyrCys: 0.198 ± 0.014
1.443TyrAsp: 1.443 ± 0.038
1.255TyrGlu: 1.255 ± 0.037
0.775TyrPhe: 0.775 ± 0.027
2.092TyrGly: 2.092 ± 0.056
0.36TyrHis: 0.36 ± 0.018
0.661TyrIle: 0.661 ± 0.027
0.597TyrLys: 0.597 ± 0.026
2.046TyrLeu: 2.046 ± 0.044
0.336TyrMet: 0.336 ± 0.018
0.469TyrAsn: 0.469 ± 0.021
0.947TyrPro: 0.947 ± 0.034
0.571TyrGln: 0.571 ± 0.025
1.582TyrArg: 1.582 ± 0.043
0.987TyrSer: 0.987 ± 0.032
0.801TyrThr: 0.801 ± 0.029
1.721TyrVal: 1.721 ± 0.038
0.314TyrTrp: 0.314 ± 0.018
0.515TyrTyr: 0.515 ± 0.025
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3283 proteins (1060935 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski