Amino acid dipepetide frequency for Vallicoccus soli

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	28.167AlaAla: 28.167 ± 0.36	1.042AlaCys: 1.042 ± 0.032	8.21AlaAsp: 8.21 ± 0.083	8.215AlaGlu: 8.215 ± 0.091	3.157AlaPhe: 3.157 ± 0.048	16.604AlaGly: 16.604 ± 0.178	2.745AlaHis: 2.745 ± 0.049	2.038AlaIle: 2.038 ± 0.051	1.534AlaLys: 1.534 ± 0.047	18.899AlaLeu: 18.899 ± 0.194	2.411AlaMet: 2.411 ± 0.044	1.348AlaAsn: 1.348 ± 0.037	9.62AlaPro: 9.62 ± 0.137	4.007AlaGln: 4.007 ± 0.062	13.61AlaArg: 13.61 ± 0.134	5.951AlaSer: 5.951 ± 0.079	7.322AlaThr: 7.322 ± 0.091	15.382AlaVal: 15.382 ± 0.157	2.251AlaTrp: 2.251 ± 0.049	2.734AlaTyr: 2.734 ± 0.053	0.0AlaXaa: 0.0 ± 0.0
Cys	1.059CysAla: 1.059 ± 0.034	0.087CysCys: 0.087 ± 0.009	0.418CysAsp: 0.418 ± 0.022	0.324CysGlu: 0.324 ± 0.018	0.158CysPhe: 0.158 ± 0.01	0.899CysGly: 0.899 ± 0.029	0.155CysHis: 0.155 ± 0.013	0.118CysIle: 0.118 ± 0.011	0.07CysLys: 0.07 ± 0.008	0.679CysLeu: 0.679 ± 0.026	0.083CysMet: 0.083 ± 0.008	0.086CysAsn: 0.086 ± 0.008	0.439CysPro: 0.439 ± 0.02	0.124CysGln: 0.124 ± 0.009	0.592CysArg: 0.592 ± 0.022	0.376CysSer: 0.376 ± 0.019	0.428CysThr: 0.428 ± 0.02	0.573CysVal: 0.573 ± 0.022	0.098CysTrp: 0.098 ± 0.009	0.118CysTyr: 0.118 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	9.234AspAla: 9.234 ± 0.102	0.331AspCys: 0.331 ± 0.017	4.069AspAsp: 4.069 ± 0.065	4.193AspGlu: 4.193 ± 0.062	1.104AspPhe: 1.104 ± 0.033	7.16AspGly: 7.16 ± 0.1	1.183AspHis: 1.183 ± 0.031	0.933AspIle: 0.933 ± 0.031	0.577AspLys: 0.577 ± 0.027	7.541AspLeu: 7.541 ± 0.077	0.55AspMet: 0.55 ± 0.018	0.525AspAsn: 0.525 ± 0.022	5.356AspPro: 5.356 ± 0.063	1.213AspGln: 1.213 ± 0.034	5.068AspArg: 5.068 ± 0.065	1.472AspSer: 1.472 ± 0.043	2.031AspThr: 2.031 ± 0.045	6.645AspVal: 6.645 ± 0.075	0.912AspTrp: 0.912 ± 0.033	0.999AspTyr: 0.999 ± 0.03	0.0AspXaa: 0.0 ± 0.0
Glu	7.733GluAla: 7.733 ± 0.078	0.265GluCys: 0.265 ± 0.016	3.441GluAsp: 3.441 ± 0.058	3.695GluGlu: 3.695 ± 0.071	0.969GluPhe: 0.969 ± 0.033	5.424GluGly: 5.424 ± 0.07	1.792GluHis: 1.792 ± 0.044	1.031GluIle: 1.031 ± 0.036	0.681GluLys: 0.681 ± 0.029	6.226GluLeu: 6.226 ± 0.086	0.601GluMet: 0.601 ± 0.026	0.527GluAsn: 0.527 ± 0.021	3.49GluPro: 3.49 ± 0.06	2.335GluGln: 2.335 ± 0.049	6.894GluArg: 6.894 ± 0.093	1.667GluSer: 1.667 ± 0.046	1.973GluThr: 1.973 ± 0.048	6.519GluVal: 6.519 ± 0.079	0.552GluTrp: 0.552 ± 0.021	0.709GluTyr: 0.709 ± 0.029	0.0GluXaa: 0.0 ± 0.0
Phe	3.012PheAla: 3.012 ± 0.052	0.204PheCys: 0.204 ± 0.014	1.567PheAsp: 1.567 ± 0.042	1.11PheGlu: 1.11 ± 0.034	0.617PhePhe: 0.617 ± 0.025	2.318PheGly: 2.318 ± 0.05	0.441PheHis: 0.441 ± 0.021	0.423PheIle: 0.423 ± 0.02	0.293PheLys: 0.293 ± 0.019	2.318PheLeu: 2.318 ± 0.048	0.256PheMet: 0.256 ± 0.015	0.34PheAsn: 0.34 ± 0.016	1.127PhePro: 1.127 ± 0.034	0.501PheGln: 0.501 ± 0.022	1.619PheArg: 1.619 ± 0.04	1.037PheSer: 1.037 ± 0.032	1.38PheThr: 1.38 ± 0.033	2.237PheVal: 2.237 ± 0.049	0.298PheTrp: 0.298 ± 0.016	0.446PheTyr: 0.446 ± 0.018	0.0PheXaa: 0.0 ± 0.0
Gly	15.685GlyAla: 15.685 ± 0.18	0.831GlyCys: 0.831 ± 0.029	5.765GlyAsp: 5.765 ± 0.079	5.631GlyGlu: 5.631 ± 0.079	2.497GlyPhe: 2.497 ± 0.046	10.582GlyGly: 10.582 ± 0.132	2.065GlyHis: 2.065 ± 0.044	2.333GlyIle: 2.333 ± 0.055	1.366GlyLys: 1.366 ± 0.038	10.825GlyLeu: 10.825 ± 0.114	1.774GlyMet: 1.774 ± 0.038	1.056GlyAsn: 1.056 ± 0.034	6.521GlyPro: 6.521 ± 0.091	2.534GlyGln: 2.534 ± 0.048	9.485GlyArg: 9.485 ± 0.098	5.037GlySer: 5.037 ± 0.072	6.597GlyThr: 6.597 ± 0.079	9.162GlyVal: 9.162 ± 0.104	1.783GlyTrp: 1.783 ± 0.039	1.975GlyTyr: 1.975 ± 0.036	0.0GlyXaa: 0.0 ± 0.0
His	2.642HisAla: 2.642 ± 0.049	0.172HisCys: 0.172 ± 0.013	1.358HisAsp: 1.358 ± 0.035	1.248HisGlu: 1.248 ± 0.03	0.426HisPhe: 0.426 ± 0.017	2.351HisGly: 2.351 ± 0.044	0.575HisHis: 0.575 ± 0.023	0.26HisIle: 0.26 ± 0.017	0.185HisLys: 0.185 ± 0.013	2.434HisLeu: 2.434 ± 0.049	0.199HisMet: 0.199 ± 0.013	0.232HisAsn: 0.232 ± 0.014	1.592HisPro: 1.592 ± 0.039	0.463HisGln: 0.463 ± 0.021	2.035HisArg: 2.035 ± 0.046	0.549HisSer: 0.549 ± 0.022	0.682HisThr: 0.682 ± 0.027	2.079HisVal: 2.079 ± 0.045	0.274HisTrp: 0.274 ± 0.015	0.367HisTyr: 0.367 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	2.788IleAla: 2.788 ± 0.063	0.123IleCys: 0.123 ± 0.011	1.343IleAsp: 1.343 ± 0.039	1.066IleGlu: 1.066 ± 0.039	0.365IlePhe: 0.365 ± 0.019	1.986IleGly: 1.986 ± 0.049	0.272IleHis: 0.272 ± 0.012	0.422IleIle: 0.422 ± 0.022	0.333IleLys: 0.333 ± 0.016	1.263IleLeu: 1.263 ± 0.039	0.214IleMet: 0.214 ± 0.014	0.341IleAsn: 0.341 ± 0.019	0.894IlePro: 0.894 ± 0.03	0.392IleGln: 0.392 ± 0.021	1.022IleArg: 1.022 ± 0.036	0.813IleSer: 0.813 ± 0.029	1.176IleThr: 1.176 ± 0.033	1.726IleVal: 1.726 ± 0.049	0.154IleTrp: 0.154 ± 0.013	0.28IleTyr: 0.28 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	1.539LysAla: 1.539 ± 0.047	0.063LysCys: 0.063 ± 0.008	0.664LysAsp: 0.664 ± 0.026	0.602LysGlu: 0.602 ± 0.027	0.19LysPhe: 0.19 ± 0.013	1.072LysGly: 1.072 ± 0.038	0.264LysHis: 0.264 ± 0.016	0.323LysIle: 0.323 ± 0.018	0.274LysLys: 0.274 ± 0.022	1.026LysLeu: 1.026 ± 0.035	0.172LysMet: 0.172 ± 0.014	0.214LysAsn: 0.214 ± 0.014	0.633LysPro: 0.633 ± 0.024	0.379LysGln: 0.379 ± 0.021	0.949LysArg: 0.949 ± 0.038	0.535LysSer: 0.535 ± 0.026	0.626LysThr: 0.626 ± 0.025	1.304LysVal: 1.304 ± 0.042	0.116LysTrp: 0.116 ± 0.011	0.244LysTyr: 0.244 ± 0.016	0.0LysXaa: 0.0 ± 0.0
Leu	18.54LeuAla: 18.54 ± 0.201	0.746LeuCys: 0.746 ± 0.025	7.701LeuAsp: 7.701 ± 0.076	5.924LeuGlu: 5.924 ± 0.081	2.114LeuPhe: 2.114 ± 0.044	11.099LeuGly: 11.099 ± 0.115	2.189LeuHis: 2.189 ± 0.042	1.376LeuIle: 1.376 ± 0.035	1.064LeuLys: 1.064 ± 0.037	13.336LeuLeu: 13.336 ± 0.179	1.106LeuMet: 1.106 ± 0.033	1.032LeuAsn: 1.032 ± 0.032	7.096LeuPro: 7.096 ± 0.075	2.677LeuGln: 2.677 ± 0.051	10.433LeuArg: 10.433 ± 0.094	4.481LeuSer: 4.481 ± 0.061	5.268LeuThr: 5.268 ± 0.069	12.484LeuVal: 12.484 ± 0.131	1.216LeuTrp: 1.216 ± 0.033	1.505LeuTyr: 1.505 ± 0.039	0.0LeuXaa: 0.0 ± 0.0
Met	2.001MetAla: 2.001 ± 0.039	0.083MetCys: 0.083 ± 0.009	0.712MetAsp: 0.712 ± 0.026	0.525MetGlu: 0.525 ± 0.021	0.287MetPhe: 0.287 ± 0.015	1.147MetGly: 1.147 ± 0.028	0.275MetHis: 0.275 ± 0.014	0.28MetIle: 0.28 ± 0.015	0.199MetLys: 0.199 ± 0.012	1.355MetLeu: 1.355 ± 0.034	0.169MetMet: 0.169 ± 0.013	0.196MetAsn: 0.196 ± 0.013	0.966MetPro: 0.966 ± 0.029	0.387MetGln: 0.387 ± 0.02	1.189MetArg: 1.189 ± 0.032	1.033MetSer: 1.033 ± 0.028	1.117MetThr: 1.117 ± 0.031	1.116MetVal: 1.116 ± 0.034	0.111MetTrp: 0.111 ± 0.01	0.215MetTyr: 0.215 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	1.501AsnAla: 1.501 ± 0.038	0.097AsnCys: 0.097 ± 0.009	0.67AsnAsp: 0.67 ± 0.026	0.553AsnGlu: 0.553 ± 0.024	0.276AsnPhe: 0.276 ± 0.017	1.018AsnGly: 1.018 ± 0.033	0.237AsnHis: 0.237 ± 0.012	0.31AsnIle: 0.31 ± 0.015	0.172AsnLys: 0.172 ± 0.015	1.204AsnLeu: 1.204 ± 0.033	0.147AsnMet: 0.147 ± 0.013	0.231AsnAsn: 0.231 ± 0.014	0.9AsnPro: 0.9 ± 0.026	0.297AsnGln: 0.297 ± 0.017	0.822AsnArg: 0.822 ± 0.028	0.42AsnSer: 0.42 ± 0.021	0.547AsnThr: 0.547 ± 0.026	1.125AsnVal: 1.125 ± 0.031	0.146AsnTrp: 0.146 ± 0.012	0.232AsnTyr: 0.232 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	10.869ProAla: 10.869 ± 0.132	0.334ProCys: 0.334 ± 0.017	4.48ProAsp: 4.48 ± 0.058	4.125ProGlu: 4.125 ± 0.062	1.398ProPhe: 1.398 ± 0.033	8.038ProGly: 8.038 ± 0.096	1.214ProHis: 1.214 ± 0.034	0.709ProIle: 0.709 ± 0.024	0.547ProLys: 0.547 ± 0.026	6.105ProLeu: 6.105 ± 0.079	0.816ProMet: 0.816 ± 0.029	0.544ProAsn: 0.544 ± 0.02	4.234ProPro: 4.234 ± 0.076	1.666ProGln: 1.666 ± 0.036	5.152ProArg: 5.152 ± 0.084	2.981ProSer: 2.981 ± 0.055	2.984ProThr: 2.984 ± 0.059	6.593ProVal: 6.593 ± 0.074	1.039ProTrp: 1.039 ± 0.03	1.229ProTyr: 1.229 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	3.47GlnAla: 3.47 ± 0.059	0.139GlnCys: 0.139 ± 0.011	1.563GlnAsp: 1.563 ± 0.039	1.58GlnGlu: 1.58 ± 0.041	0.489GlnPhe: 0.489 ± 0.022	2.462GlnGly: 2.462 ± 0.043	0.56GlnHis: 0.56 ± 0.021	0.505GlnIle: 0.505 ± 0.022	0.315GlnLys: 0.315 ± 0.017	2.665GlnLeu: 2.665 ± 0.054	0.323GlnMet: 0.323 ± 0.015	0.27GlnAsn: 0.27 ± 0.017	1.523GlnPro: 1.523 ± 0.038	1.06GlnGln: 1.06 ± 0.037	2.841GlnArg: 2.841 ± 0.049	0.896GlnSer: 0.896 ± 0.03	0.99GlnThr: 0.99 ± 0.031	3.026GlnVal: 3.026 ± 0.046	0.356GlnTrp: 0.356 ± 0.02	0.418GlnTyr: 0.418 ± 0.019	0.0GlnXaa: 0.0 ± 0.0
Arg	13.443ArgAla: 13.443 ± 0.135	0.641ArgCys: 0.641 ± 0.022	5.014ArgAsp: 5.014 ± 0.075	5.357ArgGlu: 5.357 ± 0.078	2.149ArgPhe: 2.149 ± 0.045	7.968ArgGly: 7.968 ± 0.104	1.925ArgHis: 1.925 ± 0.039	1.902ArgIle: 1.902 ± 0.046	0.892ArgLys: 0.892 ± 0.028	9.992ArgLeu: 9.992 ± 0.106	1.599ArgMet: 1.599 ± 0.039	0.886ArgAsn: 0.886 ± 0.027	5.951ArgPro: 5.951 ± 0.094	1.979ArgGln: 1.979 ± 0.044	10.524ArgArg: 10.524 ± 0.146	4.386ArgSer: 4.386 ± 0.067	5.339ArgThr: 5.339 ± 0.065	8.302ArgVal: 8.302 ± 0.099	1.66ArgTrp: 1.66 ± 0.038	1.676ArgTyr: 1.676 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	5.966SerAla: 5.966 ± 0.065	0.323SerCys: 0.323 ± 0.016	2.133SerAsp: 2.133 ± 0.047	1.852SerGlu: 1.852 ± 0.04	1.233SerPhe: 1.233 ± 0.04	5.14SerGly: 5.14 ± 0.083	0.661SerHis: 0.661 ± 0.022	0.945SerIle: 0.945 ± 0.033	0.521SerLys: 0.521 ± 0.022	4.246SerLeu: 4.246 ± 0.06	0.713SerMet: 0.713 ± 0.023	0.577SerAsn: 0.577 ± 0.023	2.805SerPro: 2.805 ± 0.053	0.921SerGln: 0.921 ± 0.027	3.425SerArg: 3.425 ± 0.05	2.307SerSer: 2.307 ± 0.052	2.885SerThr: 2.885 ± 0.049	3.834SerVal: 3.834 ± 0.063	0.766SerTrp: 0.766 ± 0.027	1.025SerTyr: 1.025 ± 0.033	0.0SerXaa: 0.0 ± 0.0
Thr	7.859ThrAla: 7.859 ± 0.096	0.405ThrCys: 0.405 ± 0.017	2.663ThrAsp: 2.663 ± 0.05	2.213ThrGlu: 2.213 ± 0.051	1.238ThrPhe: 1.238 ± 0.037	6.469ThrGly: 6.469 ± 0.075	0.834ThrHis: 0.834 ± 0.028	1.04ThrIle: 1.04 ± 0.036	0.648ThrLys: 0.648 ± 0.029	4.872ThrLeu: 4.872 ± 0.06	0.694ThrMet: 0.694 ± 0.025	0.717ThrAsn: 0.717 ± 0.025	3.424ThrPro: 3.424 ± 0.07	1.047ThrGln: 1.047 ± 0.029	3.787ThrArg: 3.787 ± 0.056	2.734ThrSer: 2.734 ± 0.054	3.694ThrThr: 3.694 ± 0.065	5.338ThrVal: 5.338 ± 0.072	0.901ThrTrp: 0.901 ± 0.029	1.193ThrTyr: 1.193 ± 0.036	0.0ThrXaa: 0.0 ± 0.0
Val	15.269ValAla: 15.269 ± 0.146	0.71ValCys: 0.71 ± 0.025	6.946ValAsp: 6.946 ± 0.078	6.473ValGlu: 6.473 ± 0.089	1.999ValPhe: 1.999 ± 0.048	8.696ValGly: 8.696 ± 0.098	2.122ValHis: 2.122 ± 0.045	1.575ValIle: 1.575 ± 0.044	1.124ValLys: 1.124 ± 0.037	13.001ValLeu: 13.001 ± 0.139	1.141ValMet: 1.141 ± 0.035	1.293ValAsn: 1.293 ± 0.032	6.869ValPro: 6.869 ± 0.092	2.506ValGln: 2.506 ± 0.044	9.194ValArg: 9.194 ± 0.101	4.011ValSer: 4.011 ± 0.066	5.119ValThr: 5.119 ± 0.077	12.874ValVal: 12.874 ± 0.131	1.086ValTrp: 1.086 ± 0.036	1.37ValTyr: 1.37 ± 0.034	0.0ValXaa: 0.0 ± 0.0
Trp	1.787TrpAla: 1.787 ± 0.045	0.144TrpCys: 0.144 ± 0.012	0.933TrpAsp: 0.933 ± 0.031	0.681TrpGlu: 0.681 ± 0.024	0.43TrpPhe: 0.43 ± 0.023	1.119TrpGly: 1.119 ± 0.027	0.327TrpHis: 0.327 ± 0.014	0.232TrpIle: 0.232 ± 0.014	0.174TrpLys: 0.174 ± 0.012	1.613TrpLeu: 1.613 ± 0.04	0.234TrpMet: 0.234 ± 0.013	0.254TrpAsn: 0.254 ± 0.017	0.75TrpPro: 0.75 ± 0.025	0.512TrpGln: 0.512 ± 0.02	1.388TrpArg: 1.388 ± 0.033	0.899TrpSer: 0.899 ± 0.029	0.894TrpThr: 0.894 ± 0.028	1.303TrpVal: 1.303 ± 0.034	0.355TrpTrp: 0.355 ± 0.015	0.298TrpTyr: 0.298 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.685TyrAla: 2.685 ± 0.05	0.144TyrCys: 0.144 ± 0.01	1.448TyrAsp: 1.448 ± 0.038	1.156TyrGlu: 1.156 ± 0.03	0.45TyrPhe: 0.45 ± 0.019	1.952TyrGly: 1.952 ± 0.044	0.286TyrHis: 0.286 ± 0.015	0.219TyrIle: 0.219 ± 0.017	0.22TyrLys: 0.22 ± 0.014	1.786TyrLeu: 1.786 ± 0.04	0.159TyrMet: 0.159 ± 0.012	0.237TyrAsn: 0.237 ± 0.016	0.864TyrPro: 0.864 ± 0.028	0.447TyrGln: 0.447 ± 0.02	1.557TyrArg: 1.557 ± 0.044	0.695TyrSer: 0.695 ± 0.028	0.718TyrThr: 0.718 ± 0.03	1.758TyrVal: 1.758 ± 0.038	0.254TyrTrp: 0.254 ± 0.013	0.373TyrTyr: 0.373 ± 0.021	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3658 proteins (1198445 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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