Amino acid dipepetide frequency for Seleniivibrio woodruffii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.529AlaAla: 8.529 ± 0.238	1.068AlaCys: 1.068 ± 0.04	5.537AlaAsp: 5.537 ± 0.085	6.683AlaGlu: 6.683 ± 0.106	3.363AlaPhe: 3.363 ± 0.068	6.752AlaGly: 6.752 ± 0.111	1.296AlaHis: 1.296 ± 0.039	4.636AlaIle: 4.636 ± 0.091	5.407AlaLys: 5.407 ± 0.098	7.124AlaLeu: 7.124 ± 0.103	2.519AlaMet: 2.519 ± 0.062	2.669AlaAsn: 2.669 ± 0.054	2.248AlaPro: 2.248 ± 0.058	2.433AlaGln: 2.433 ± 0.106	2.979AlaArg: 2.979 ± 0.057	4.686AlaSer: 4.686 ± 0.084	3.261AlaThr: 3.261 ± 0.078	7.299AlaVal: 7.299 ± 0.106	0.496AlaTrp: 0.496 ± 0.026	2.659AlaTyr: 2.659 ± 0.059	0.0AlaXaa: 0.0 ± 0.0
Cys	0.968CysAla: 0.968 ± 0.034	0.187CysCys: 0.187 ± 0.016	0.668CysAsp: 0.668 ± 0.031	0.734CysGlu: 0.734 ± 0.029	0.52CysPhe: 0.52 ± 0.025	1.32CysGly: 1.32 ± 0.045	0.488CysHis: 0.488 ± 0.054	0.79CysIle: 0.79 ± 0.032	0.588CysLys: 0.588 ± 0.026	0.864CysLeu: 0.864 ± 0.037	0.339CysMet: 0.339 ± 0.02	0.35CysAsn: 0.35 ± 0.022	0.637CysPro: 0.637 ± 0.034	0.26CysGln: 0.26 ± 0.018	0.662CysArg: 0.662 ± 0.029	0.831CysSer: 0.831 ± 0.039	0.631CysThr: 0.631 ± 0.029	0.9CysVal: 0.9 ± 0.04	0.074CysTrp: 0.074 ± 0.009	0.373CysTyr: 0.373 ± 0.023	0.0CysXaa: 0.0 ± 0.0
Asp	4.299AspAla: 4.299 ± 0.077	0.72AspCys: 0.72 ± 0.033	2.894AspAsp: 2.894 ± 0.067	4.184AspGlu: 4.184 ± 0.082	3.142AspPhe: 3.142 ± 0.064	4.176AspGly: 4.176 ± 0.094	0.858AspHis: 0.858 ± 0.029	5.477AspIle: 5.477 ± 0.093	3.924AspLys: 3.924 ± 0.077	4.118AspLeu: 4.118 ± 0.08	2.01AspMet: 2.01 ± 0.048	2.336AspAsn: 2.336 ± 0.057	1.892AspPro: 1.892 ± 0.052	0.913AspGln: 0.913 ± 0.035	3.076AspArg: 3.076 ± 0.065	3.649AspSer: 3.649 ± 0.078	3.279AspThr: 3.279 ± 0.069	3.966AspVal: 3.966 ± 0.078	0.502AspTrp: 0.502 ± 0.024	2.258AspTyr: 2.258 ± 0.042	0.0AspXaa: 0.0 ± 0.0
Glu	5.1GluAla: 5.1 ± 0.076	0.637GluCys: 0.637 ± 0.029	3.481GluAsp: 3.481 ± 0.075	4.458GluGlu: 4.458 ± 0.095	2.711GluPhe: 2.711 ± 0.06	3.97GluGly: 3.97 ± 0.069	1.295GluHis: 1.295 ± 0.041	5.218GluIle: 5.218 ± 0.091	6.194GluLys: 6.194 ± 0.11	6.47GluLeu: 6.47 ± 0.104	2.16GluMet: 2.16 ± 0.053	3.639GluAsn: 3.639 ± 0.064	1.868GluPro: 1.868 ± 0.049	2.252GluGln: 2.252 ± 0.057	3.17GluArg: 3.17 ± 0.068	3.578GluSer: 3.578 ± 0.068	3.811GluThr: 3.811 ± 0.064	4.236GluVal: 4.236 ± 0.083	0.53GluTrp: 0.53 ± 0.029	2.627GluTyr: 2.627 ± 0.052	0.0GluXaa: 0.0 ± 0.0
Phe	3.793PheAla: 3.793 ± 0.073	0.647PheCys: 0.647 ± 0.026	2.882PheAsp: 2.882 ± 0.063	2.833PheGlu: 2.833 ± 0.061	2.498PhePhe: 2.498 ± 0.067	3.633PheGly: 3.633 ± 0.069	0.794PheHis: 0.794 ± 0.029	3.446PheIle: 3.446 ± 0.077	2.56PheLys: 2.56 ± 0.057	4.02PheLeu: 4.02 ± 0.073	1.44PheMet: 1.44 ± 0.05	1.983PheAsn: 1.983 ± 0.049	1.54PhePro: 1.54 ± 0.047	1.029PheGln: 1.029 ± 0.033	2.339PheArg: 2.339 ± 0.054	3.655PheSer: 3.655 ± 0.07	2.807PheThr: 2.807 ± 0.065	3.065PheVal: 3.065 ± 0.066	0.4PheTrp: 0.4 ± 0.021	1.741PheTyr: 1.741 ± 0.048	0.0PheXaa: 0.0 ± 0.0
Gly	5.094GlyAla: 5.094 ± 0.095	1.115GlyCys: 1.115 ± 0.037	3.7GlyAsp: 3.7 ± 0.083	4.34GlyGlu: 4.34 ± 0.078	3.792GlyPhe: 3.792 ± 0.068	5.453GlyGly: 5.453 ± 0.135	1.397GlyHis: 1.397 ± 0.043	5.81GlyIle: 5.81 ± 0.09	5.257GlyLys: 5.257 ± 0.082	6.388GlyLeu: 6.388 ± 0.09	2.362GlyMet: 2.362 ± 0.048	2.733GlyAsn: 2.733 ± 0.071	1.196GlyPro: 1.196 ± 0.042	1.942GlyGln: 1.942 ± 0.059	3.698GlyArg: 3.698 ± 0.078	4.317GlySer: 4.317 ± 0.085	4.108GlyThr: 4.108 ± 0.108	5.218GlyVal: 5.218 ± 0.076	0.66GlyTrp: 0.66 ± 0.029	2.99GlyTyr: 2.99 ± 0.068	0.0GlyXaa: 0.0 ± 0.0
His	1.156HisAla: 1.156 ± 0.038	0.251HisCys: 0.251 ± 0.018	0.982HisAsp: 0.982 ± 0.033	1.104HisGlu: 1.104 ± 0.035	0.871HisPhe: 0.871 ± 0.033	1.359HisGly: 1.359 ± 0.04	0.395HisHis: 0.395 ± 0.021	1.404HisIle: 1.404 ± 0.04	1.097HisLys: 1.097 ± 0.043	1.489HisLeu: 1.489 ± 0.049	0.553HisMet: 0.553 ± 0.027	0.77HisAsn: 0.77 ± 0.031	0.863HisPro: 0.863 ± 0.032	0.44HisGln: 0.44 ± 0.019	0.868HisArg: 0.868 ± 0.028	1.127HisSer: 1.127 ± 0.037	1.028HisThr: 1.028 ± 0.036	1.088HisVal: 1.088 ± 0.044	0.139HisTrp: 0.139 ± 0.013	0.649HisTyr: 0.649 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	5.794IleAla: 5.794 ± 0.096	0.882IleCys: 0.882 ± 0.031	4.29IleAsp: 4.29 ± 0.074	4.793IleGlu: 4.793 ± 0.083	3.285IlePhe: 3.285 ± 0.07	4.805IleGly: 4.805 ± 0.079	1.187IleHis: 1.187 ± 0.037	5.556IleIle: 5.556 ± 0.098	4.965IleLys: 4.965 ± 0.076	6.312IleLeu: 6.312 ± 0.095	1.895IleMet: 1.895 ± 0.05	3.426IleAsn: 3.426 ± 0.068	2.753IlePro: 2.753 ± 0.06	1.767IleGln: 1.767 ± 0.049	3.284IleArg: 3.284 ± 0.058	5.353IleSer: 5.353 ± 0.089	4.358IleThr: 4.358 ± 0.088	4.7IleVal: 4.7 ± 0.069	0.427IleTrp: 0.427 ± 0.021	2.509IleTyr: 2.509 ± 0.054	0.0IleXaa: 0.0 ± 0.0
Lys	5.345LysAla: 5.345 ± 0.099	0.765LysCys: 0.765 ± 0.037	4.381LysAsp: 4.381 ± 0.074	5.13LysGlu: 5.13 ± 0.09	2.556LysPhe: 2.556 ± 0.062	4.698LysGly: 4.698 ± 0.081	1.165LysHis: 1.165 ± 0.039	4.717LysIle: 4.717 ± 0.082	5.471LysLys: 5.471 ± 0.114	6.132LysLeu: 6.132 ± 0.09	2.241LysMet: 2.241 ± 0.053	3.611LysAsn: 3.611 ± 0.066	2.621LysPro: 2.621 ± 0.057	2.061LysGln: 2.061 ± 0.049	2.973LysArg: 2.973 ± 0.061	4.108LysSer: 4.108 ± 0.086	4.021LysThr: 4.021 ± 0.08	4.337LysVal: 4.337 ± 0.084	0.444LysTrp: 0.444 ± 0.023	2.724LysTyr: 2.724 ± 0.061	0.0LysXaa: 0.0 ± 0.0
Leu	7.577LeuAla: 7.577 ± 0.101	1.02LeuCys: 1.02 ± 0.038	4.808LeuAsp: 4.808 ± 0.08	5.565LeuGlu: 5.565 ± 0.088	4.225LeuPhe: 4.225 ± 0.082	5.865LeuGly: 5.865 ± 0.1	1.504LeuHis: 1.504 ± 0.046	5.965LeuIle: 5.965 ± 0.096	7.222LeuLys: 7.222 ± 0.113	7.844LeuLeu: 7.844 ± 0.11	2.637LeuMet: 2.637 ± 0.057	4.406LeuAsn: 4.406 ± 0.077	3.365LeuPro: 3.365 ± 0.068	2.068LeuGln: 2.068 ± 0.054	3.961LeuArg: 3.961 ± 0.077	6.453LeuSer: 6.453 ± 0.089	5.341LeuThr: 5.341 ± 0.091	5.484LeuVal: 5.484 ± 0.083	0.579LeuTrp: 0.579 ± 0.026	2.834LeuTyr: 2.834 ± 0.066	0.0LeuXaa: 0.0 ± 0.0
Met	2.537MetAla: 2.537 ± 0.054	0.28MetCys: 0.28 ± 0.017	1.632MetAsp: 1.632 ± 0.046	1.754MetGlu: 1.754 ± 0.047	1.277MetPhe: 1.277 ± 0.04	2.08MetGly: 2.08 ± 0.052	0.565MetHis: 0.565 ± 0.025	1.889MetIle: 1.889 ± 0.045	2.574MetLys: 2.574 ± 0.053	2.947MetLeu: 2.947 ± 0.065	0.908MetMet: 0.908 ± 0.035	1.473MetAsn: 1.473 ± 0.039	1.371MetPro: 1.371 ± 0.044	0.965MetGln: 0.965 ± 0.032	1.42MetArg: 1.42 ± 0.046	2.09MetSer: 2.09 ± 0.053	1.823MetThr: 1.823 ± 0.043	1.915MetVal: 1.915 ± 0.045	0.2MetTrp: 0.2 ± 0.014	0.813MetTyr: 0.813 ± 0.031	0.0MetXaa: 0.0 ± 0.0
Asn	3.201AsnAla: 3.201 ± 0.067	0.516AsnCys: 0.516 ± 0.026	2.168AsnAsp: 2.168 ± 0.048	2.509AsnGlu: 2.509 ± 0.053	1.899AsnPhe: 1.899 ± 0.05	3.167AsnGly: 3.167 ± 0.068	0.728AsnHis: 0.728 ± 0.03	3.918AsnIle: 3.918 ± 0.084	2.442AsnLys: 2.442 ± 0.055	3.987AsnLeu: 3.987 ± 0.08	1.36AsnMet: 1.36 ± 0.042	1.837AsnAsn: 1.837 ± 0.05	2.126AsnPro: 2.126 ± 0.042	0.918AsnGln: 0.918 ± 0.033	2.294AsnArg: 2.294 ± 0.052	2.768AsnSer: 2.768 ± 0.065	2.373AsnThr: 2.373 ± 0.063	3.082AsnVal: 3.082 ± 0.059	0.314AsnTrp: 0.314 ± 0.017	1.465AsnTyr: 1.465 ± 0.047	0.0AsnXaa: 0.0 ± 0.0
Pro	3.113ProAla: 3.113 ± 0.068	0.386ProCys: 0.386 ± 0.021	2.578ProAsp: 2.578 ± 0.059	3.385ProGlu: 3.385 ± 0.064	1.755ProPhe: 1.755 ± 0.048	1.906ProGly: 1.906 ± 0.052	0.67ProHis: 0.67 ± 0.026	1.736ProIle: 1.736 ± 0.051	2.011ProLys: 2.011 ± 0.056	2.909ProLeu: 2.909 ± 0.062	0.992ProMet: 0.992 ± 0.035	1.139ProAsn: 1.139 ± 0.036	0.907ProPro: 0.907 ± 0.033	1.073ProGln: 1.073 ± 0.042	1.019ProArg: 1.019 ± 0.038	2.032ProSer: 2.032 ± 0.049	1.536ProThr: 1.536 ± 0.042	3.564ProVal: 3.564 ± 0.063	0.255ProTrp: 0.255 ± 0.018	1.353ProTyr: 1.353 ± 0.041	0.0ProXaa: 0.0 ± 0.0
Gln	2.302GlnAla: 2.302 ± 0.087	0.268GlnCys: 0.268 ± 0.019	1.324GlnAsp: 1.324 ± 0.043	1.842GlnGlu: 1.842 ± 0.051	1.106GlnPhe: 1.106 ± 0.033	1.633GlnGly: 1.633 ± 0.046	0.435GlnHis: 0.435 ± 0.023	1.841GlnIle: 1.841 ± 0.051	2.112GlnLys: 2.112 ± 0.055	2.226GlnLeu: 2.226 ± 0.056	0.93GlnMet: 0.93 ± 0.036	1.327GlnAsn: 1.327 ± 0.04	0.99GlnPro: 0.99 ± 0.042	0.934GlnGln: 0.934 ± 0.036	1.159GlnArg: 1.159 ± 0.033	1.683GlnSer: 1.683 ± 0.055	1.63GlnThr: 1.63 ± 0.042	1.719GlnVal: 1.719 ± 0.046	0.209GlnTrp: 0.209 ± 0.015	0.996GlnTyr: 0.996 ± 0.039	0.0GlnXaa: 0.0 ± 0.0
Arg	2.96ArgAla: 2.96 ± 0.062	0.495ArgCys: 0.495 ± 0.029	2.438ArgAsp: 2.438 ± 0.051	3.133ArgGlu: 3.133 ± 0.07	2.366ArgPhe: 2.366 ± 0.056	2.443ArgGly: 2.443 ± 0.057	0.878ArgHis: 0.878 ± 0.033	3.735ArgIle: 3.735 ± 0.08	3.301ArgLys: 3.301 ± 0.07	4.551ArgLeu: 4.551 ± 0.085	1.58ArgMet: 1.58 ± 0.046	2.128ArgAsn: 2.128 ± 0.053	1.522ArgPro: 1.522 ± 0.059	1.591ArgGln: 1.591 ± 0.042	2.171ArgArg: 2.171 ± 0.059	2.548ArgSer: 2.548 ± 0.057	2.459ArgThr: 2.459 ± 0.054	3.066ArgVal: 3.066 ± 0.061	0.345ArgTrp: 0.345 ± 0.021	1.788ArgTyr: 1.788 ± 0.05	0.0ArgXaa: 0.0 ± 0.0
Ser	5.694SerAla: 5.694 ± 0.1	0.776SerCys: 0.776 ± 0.036	3.682SerAsp: 3.682 ± 0.072	4.256SerGlu: 4.256 ± 0.07	3.263SerPhe: 3.263 ± 0.065	5.815SerGly: 5.815 ± 0.12	1.038SerHis: 1.038 ± 0.034	4.42SerIle: 4.42 ± 0.077	3.775SerLys: 3.775 ± 0.061	5.651SerLeu: 5.651 ± 0.086	1.838SerMet: 1.838 ± 0.047	2.197SerAsn: 2.197 ± 0.06	2.062SerPro: 2.062 ± 0.049	1.618SerGln: 1.618 ± 0.051	2.854SerArg: 2.854 ± 0.063	4.078SerSer: 4.078 ± 0.1	2.999SerThr: 2.999 ± 0.074	5.403SerVal: 5.403 ± 0.09	0.507SerTrp: 0.507 ± 0.026	2.254SerTyr: 2.254 ± 0.049	0.0SerXaa: 0.0 ± 0.0
Thr	5.562ThrAla: 5.562 ± 0.103	0.635ThrCys: 0.635 ± 0.038	3.64ThrAsp: 3.64 ± 0.078	3.641ThrGlu: 3.641 ± 0.063	2.378ThrPhe: 2.378 ± 0.058	5.134ThrGly: 5.134 ± 0.094	0.931ThrHis: 0.931 ± 0.036	3.464ThrIle: 3.464 ± 0.071	2.982ThrLys: 2.982 ± 0.055	4.871ThrLeu: 4.871 ± 0.08	1.312ThrMet: 1.312 ± 0.035	1.88ThrAsn: 1.88 ± 0.055	2.372ThrPro: 2.372 ± 0.051	1.278ThrGln: 1.278 ± 0.042	2.018ThrArg: 2.018 ± 0.054	3.101ThrSer: 3.101 ± 0.072	2.568ThrThr: 2.568 ± 0.08	4.795ThrVal: 4.795 ± 0.101	0.323ThrTrp: 0.323 ± 0.018	1.805ThrTyr: 1.805 ± 0.049	0.0ThrXaa: 0.0 ± 0.0
Val	5.287ValAla: 5.287 ± 0.085	1.05ValCys: 1.05 ± 0.039	3.906ValAsp: 3.906 ± 0.062	4.298ValGlu: 4.298 ± 0.077	3.816ValPhe: 3.816 ± 0.074	4.172ValGly: 4.172 ± 0.07	1.195ValHis: 1.195 ± 0.041	5.281ValIle: 5.281 ± 0.069	4.998ValLys: 4.998 ± 0.092	6.692ValLeu: 6.692 ± 0.104	2.149ValMet: 2.149 ± 0.046	3.216ValAsn: 3.216 ± 0.058	2.476ValPro: 2.476 ± 0.059	1.949ValGln: 1.949 ± 0.049	3.506ValArg: 3.506 ± 0.056	5.236ValSer: 5.236 ± 0.085	4.294ValThr: 4.294 ± 0.119	5.171ValVal: 5.171 ± 0.106	0.507ValTrp: 0.507 ± 0.026	2.584ValTyr: 2.584 ± 0.058	0.0ValXaa: 0.0 ± 0.0
Trp	0.556TrpAla: 0.556 ± 0.026	0.076TrpCys: 0.076 ± 0.01	0.385TrpAsp: 0.385 ± 0.023	0.466TrpGlu: 0.466 ± 0.024	0.385TrpPhe: 0.385 ± 0.024	0.476TrpGly: 0.476 ± 0.022	0.207TrpHis: 0.207 ± 0.017	0.431TrpIle: 0.431 ± 0.022	0.436TrpLys: 0.436 ± 0.022	0.797TrpLeu: 0.797 ± 0.029	0.249TrpMet: 0.249 ± 0.016	0.337TrpAsn: 0.337 ± 0.019	0.185TrpPro: 0.185 ± 0.016	0.297TrpGln: 0.297 ± 0.02	0.337TrpArg: 0.337 ± 0.018	0.429TrpSer: 0.429 ± 0.025	0.344TrpThr: 0.344 ± 0.02	0.483TrpVal: 0.483 ± 0.023	0.103TrpTrp: 0.103 ± 0.012	0.315TrpTyr: 0.315 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.775TyrAla: 2.775 ± 0.064	0.409TyrCys: 0.409 ± 0.026	2.299TyrAsp: 2.299 ± 0.052	2.295TyrGlu: 2.295 ± 0.054	1.898TyrPhe: 1.898 ± 0.053	2.714TyrGly: 2.714 ± 0.063	0.607TyrHis: 0.607 ± 0.03	2.61TyrIle: 2.61 ± 0.064	2.186TyrLys: 2.186 ± 0.061	3.328TyrLeu: 3.328 ± 0.07	1.038TyrMet: 1.038 ± 0.038	1.618TyrAsn: 1.618 ± 0.051	1.327TyrPro: 1.327 ± 0.045	0.879TyrGln: 0.879 ± 0.034	1.706TyrArg: 1.706 ± 0.045	2.459TyrSer: 2.459 ± 0.057	2.018TyrThr: 2.018 ± 0.054	2.289TyrVal: 2.289 ± 0.05	0.282TyrTrp: 0.282 ± 0.019	1.473TyrTyr: 1.473 ± 0.045	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2684 proteins (883181 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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