Amino acid dipepetide frequency for Bovine respiratory syncytial virus (strain A51908) (BRS)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.548AlaAla: 2.548 ± 1.212
0.849AlaCys: 0.849 ± 0.631
0.849AlaAsp: 0.849 ± 0.424
2.548AlaGlu: 2.548 ± 0.655
1.062AlaPhe: 1.062 ± 0.33
3.185AlaGly: 3.185 ± 1.251
0.637AlaHis: 0.637 ± 0.303
3.61AlaIle: 3.61 ± 0.659
4.46AlaLys: 4.46 ± 1.188
4.035AlaLeu: 4.035 ± 0.556
1.487AlaMet: 1.487 ± 0.642
2.761AlaAsn: 2.761 ± 1.096
2.124AlaPro: 2.124 ± 1.311
1.911AlaGln: 1.911 ± 0.463
1.487AlaArg: 1.487 ± 0.767
2.548AlaSer: 2.548 ± 0.622
2.761AlaThr: 2.761 ± 0.936
2.124AlaVal: 2.124 ± 0.854
0.212AlaTrp: 0.212 ± 0.301
1.487AlaTyr: 1.487 ± 0.637
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.212CysCys: 0.212 ± 0.127
1.487CysAsp: 1.487 ± 0.671
1.487CysGlu: 1.487 ± 0.63
0.425CysPhe: 0.425 ± 0.319
0.425CysGly: 0.425 ± 0.494
0.849CysHis: 0.849 ± 0.456
2.124CysIle: 2.124 ± 0.944
1.911CysLys: 1.911 ± 0.73
1.699CysLeu: 1.699 ± 0.508
0.425CysMet: 0.425 ± 0.254
1.274CysAsn: 1.274 ± 0.551
0.637CysPro: 0.637 ± 0.352
1.062CysGln: 1.062 ± 0.596
0.212CysArg: 0.212 ± 0.235
2.336CysSer: 2.336 ± 0.758
0.849CysThr: 0.849 ± 0.445
0.425CysVal: 0.425 ± 0.414
0.212CysTrp: 0.212 ± 0.235
0.425CysTyr: 0.425 ± 0.222
0.0CysXaa: 0.0 ± 0.0
Asp
2.548AspAla: 2.548 ± 0.701
1.274AspCys: 1.274 ± 0.423
1.699AspAsp: 1.699 ± 0.774
3.398AspGlu: 3.398 ± 1.425
0.849AspPhe: 0.849 ± 0.378
1.062AspGly: 1.062 ± 0.42
1.487AspHis: 1.487 ± 0.463
5.946AspIle: 5.946 ± 1.095
2.548AspLys: 2.548 ± 1.127
5.521AspLeu: 5.521 ± 1.436
1.274AspMet: 1.274 ± 0.47
4.035AspAsn: 4.035 ± 0.93
0.849AspPro: 0.849 ± 0.369
1.699AspGln: 1.699 ± 0.413
1.911AspArg: 1.911 ± 0.706
2.336AspSer: 2.336 ± 0.649
3.398AspThr: 3.398 ± 0.733
3.185AspVal: 3.185 ± 1.052
0.425AspTrp: 0.425 ± 0.254
2.124AspTyr: 2.124 ± 0.887
0.0AspXaa: 0.0 ± 0.0
Glu
2.124GluAla: 2.124 ± 0.697
0.849GluCys: 0.849 ± 0.521
1.911GluAsp: 1.911 ± 1.126
2.124GluGlu: 2.124 ± 1.382
3.398GluPhe: 3.398 ± 0.869
2.761GluGly: 2.761 ± 0.545
1.274GluHis: 1.274 ± 0.805
3.398GluIle: 3.398 ± 1.761
3.822GluLys: 3.822 ± 1.525
7.433GluLeu: 7.433 ± 1.306
1.487GluMet: 1.487 ± 1.231
2.124GluAsn: 2.124 ± 0.755
1.062GluPro: 1.062 ± 0.484
1.274GluGln: 1.274 ± 0.457
2.548GluArg: 2.548 ± 0.525
4.247GluSer: 4.247 ± 1.169
2.124GluThr: 2.124 ± 0.913
3.398GluVal: 3.398 ± 0.879
0.425GluTrp: 0.425 ± 0.321
1.911GluTyr: 1.911 ± 0.677
0.0GluXaa: 0.0 ± 0.0
Phe
1.062PheAla: 1.062 ± 0.347
0.425PheCys: 0.425 ± 0.222
1.062PheAsp: 1.062 ± 0.345
0.849PheGlu: 0.849 ± 0.481
1.487PhePhe: 1.487 ± 0.58
0.849PheGly: 0.849 ± 0.314
0.849PheHis: 0.849 ± 0.378
2.336PheIle: 2.336 ± 0.631
1.699PheLys: 1.699 ± 0.561
4.672PheLeu: 4.672 ± 1.546
1.274PheMet: 1.274 ± 0.515
2.336PheAsn: 2.336 ± 0.5
2.336PhePro: 2.336 ± 0.622
1.699PheGln: 1.699 ± 0.435
1.274PheArg: 1.274 ± 0.762
2.973PheSer: 2.973 ± 0.579
2.336PheThr: 2.336 ± 1.097
1.911PheVal: 1.911 ± 0.588
0.212PheTrp: 0.212 ± 0.274
2.336PheTyr: 2.336 ± 0.667
0.0PheXaa: 0.0 ± 0.0
Gly
1.699GlyAla: 1.699 ± 0.566
0.849GlyCys: 0.849 ± 0.367
1.911GlyAsp: 1.911 ± 0.595
2.761GlyGlu: 2.761 ± 0.614
1.487GlyPhe: 1.487 ± 0.39
1.274GlyGly: 1.274 ± 0.533
1.911GlyHis: 1.911 ± 0.491
4.247GlyIle: 4.247 ± 1.064
3.185GlyLys: 3.185 ± 0.952
5.309GlyLeu: 5.309 ± 1.081
0.849GlyMet: 0.849 ± 0.54
2.336GlyAsn: 2.336 ± 0.918
1.274GlyPro: 1.274 ± 0.479
0.425GlyGln: 0.425 ± 0.203
0.849GlyArg: 0.849 ± 0.314
2.973GlySer: 2.973 ± 0.574
1.911GlyThr: 1.911 ± 0.418
2.761GlyVal: 2.761 ± 0.993
0.637GlyTrp: 0.637 ± 0.44
1.699GlyTyr: 1.699 ± 0.462
0.0GlyXaa: 0.0 ± 0.0
His
1.274HisAla: 1.274 ± 0.432
0.637HisCys: 0.637 ± 0.459
0.849HisAsp: 0.849 ± 0.376
1.274HisGlu: 1.274 ± 0.581
0.637HisPhe: 0.637 ± 0.356
1.062HisGly: 1.062 ± 0.477
0.637HisHis: 0.637 ± 0.361
2.761HisIle: 2.761 ± 0.798
2.124HisLys: 2.124 ± 0.547
2.124HisLeu: 2.124 ± 0.496
1.062HisMet: 1.062 ± 0.472
2.124HisAsn: 2.124 ± 0.949
1.699HisPro: 1.699 ± 0.676
1.062HisGln: 1.062 ± 0.97
1.062HisArg: 1.062 ± 0.434
1.062HisSer: 1.062 ± 0.475
3.61HisThr: 3.61 ± 2.151
1.274HisVal: 1.274 ± 0.425
0.637HisTrp: 0.637 ± 0.381
0.637HisTyr: 0.637 ± 0.257
0.0HisXaa: 0.0 ± 0.0
Ile
3.398IleAla: 3.398 ± 0.946
0.849IleCys: 0.849 ± 0.367
5.734IleAsp: 5.734 ± 0.985
5.097IleGlu: 5.097 ± 1.022
2.124IlePhe: 2.124 ± 0.456
2.548IleGly: 2.548 ± 0.679
1.911IleHis: 1.911 ± 0.852
7.645IleIle: 7.645 ± 1.215
6.371IleLys: 6.371 ± 0.935
8.707IleLeu: 8.707 ± 2.268
2.336IleMet: 2.336 ± 0.773
7.645IleAsn: 7.645 ± 1.338
2.124IlePro: 2.124 ± 0.545
1.699IleGln: 1.699 ± 0.462
2.973IleArg: 2.973 ± 0.963
8.919IleSer: 8.919 ± 1.728
10.193IleThr: 10.193 ± 0.871
4.672IleVal: 4.672 ± 0.879
0.637IleTrp: 0.637 ± 0.408
3.185IleTyr: 3.185 ± 1.383
0.0IleXaa: 0.0 ± 0.0
Lys
4.46LysAla: 4.46 ± 0.777
0.637LysCys: 0.637 ± 0.358
5.097LysAsp: 5.097 ± 1.317
3.185LysGlu: 3.185 ± 1.152
4.035LysPhe: 4.035 ± 0.878
3.61LysGly: 3.61 ± 0.923
1.062LysHis: 1.062 ± 0.337
5.521LysIle: 5.521 ± 0.61
5.521LysLys: 5.521 ± 1.107
12.317LysLeu: 12.317 ± 2.057
1.062LysMet: 1.062 ± 0.295
4.035LysAsn: 4.035 ± 0.87
3.822LysPro: 3.822 ± 1.525
1.487LysGln: 1.487 ± 0.675
2.761LysArg: 2.761 ± 1.149
3.61LysSer: 3.61 ± 0.956
4.035LysThr: 4.035 ± 1.082
4.247LysVal: 4.247 ± 1.014
0.425LysTrp: 0.425 ± 0.254
4.672LysTyr: 4.672 ± 1.2
0.0LysXaa: 0.0 ± 0.0
Leu
3.61LeuAla: 3.61 ± 0.872
3.185LeuCys: 3.185 ± 0.563
4.46LeuAsp: 4.46 ± 0.912
6.371LeuGlu: 6.371 ± 0.864
2.973LeuPhe: 2.973 ± 1.317
4.672LeuGly: 4.672 ± 0.897
3.185LeuHis: 3.185 ± 0.695
8.707LeuIle: 8.707 ± 1.981
9.131LeuLys: 9.131 ± 1.708
8.707LeuLeu: 8.707 ± 1.401
2.973LeuMet: 2.973 ± 0.683
8.07LeuAsn: 8.07 ± 2.47
4.884LeuPro: 4.884 ± 1.047
2.336LeuGln: 2.336 ± 0.532
4.035LeuArg: 4.035 ± 0.638
12.104LeuSer: 12.104 ± 1.533
9.344LeuThr: 9.344 ± 1.201
4.247LeuVal: 4.247 ± 1.554
0.425LeuTrp: 0.425 ± 0.254
5.097LeuTyr: 5.097 ± 1.479
0.0LeuXaa: 0.0 ± 0.0
Met
0.849MetAla: 0.849 ± 0.363
0.0MetCys: 0.0 ± 0.0
0.849MetAsp: 0.849 ± 0.426
1.487MetGlu: 1.487 ± 0.532
1.274MetPhe: 1.274 ± 0.583
1.274MetGly: 1.274 ± 0.517
0.0MetHis: 0.0 ± 0.0
2.124MetIle: 2.124 ± 0.505
1.487MetLys: 1.487 ± 0.552
3.61MetLeu: 3.61 ± 1.212
0.425MetMet: 0.425 ± 0.26
1.274MetAsn: 1.274 ± 0.395
1.487MetPro: 1.487 ± 0.444
0.849MetGln: 0.849 ± 0.367
0.637MetArg: 0.637 ± 0.275
2.761MetSer: 2.761 ± 0.654
1.062MetThr: 1.062 ± 0.637
0.637MetVal: 0.637 ± 0.541
0.0MetTrp: 0.0 ± 0.0
0.425MetTyr: 0.425 ± 0.228
0.0MetXaa: 0.0 ± 0.0
Asn
3.61AsnAla: 3.61 ± 0.934
1.062AsnCys: 1.062 ± 0.515
4.884AsnAsp: 4.884 ± 1.621
2.548AsnGlu: 2.548 ± 0.667
1.699AsnPhe: 1.699 ± 0.56
3.185AsnGly: 3.185 ± 0.992
3.822AsnHis: 3.822 ± 1.54
7.22AsnIle: 7.22 ± 0.812
5.946AsnLys: 5.946 ± 1.235
4.46AsnLeu: 4.46 ± 2.039
0.849AsnMet: 0.849 ± 0.713
5.734AsnAsn: 5.734 ± 1.125
3.398AsnPro: 3.398 ± 1.642
4.672AsnGln: 4.672 ± 0.823
3.61AsnArg: 3.61 ± 0.845
4.035AsnSer: 4.035 ± 0.628
4.035AsnThr: 4.035 ± 0.988
3.61AsnVal: 3.61 ± 1.012
0.425AsnTrp: 0.425 ± 0.25
3.185AsnTyr: 3.185 ± 0.665
0.0AsnXaa: 0.0 ± 0.0
Pro
1.911ProAla: 1.911 ± 0.512
1.487ProCys: 1.487 ± 0.676
1.487ProAsp: 1.487 ± 0.653
2.761ProGlu: 2.761 ± 1.435
1.062ProPhe: 1.062 ± 0.477
0.212ProGly: 0.212 ± 0.127
1.699ProHis: 1.699 ± 0.443
4.247ProIle: 4.247 ± 0.76
3.822ProLys: 3.822 ± 1.036
3.61ProLeu: 3.61 ± 1.866
1.274ProMet: 1.274 ± 0.589
2.548ProAsn: 2.548 ± 0.63
1.911ProPro: 1.911 ± 0.797
1.699ProGln: 1.699 ± 0.792
0.212ProArg: 0.212 ± 0.247
2.973ProSer: 2.973 ± 0.634
5.309ProThr: 5.309 ± 1.995
0.212ProVal: 0.212 ± 0.127
0.849ProTrp: 0.849 ± 0.508
0.849ProTyr: 0.849 ± 0.373
0.0ProXaa: 0.0 ± 0.0
Gln
1.699GlnAla: 1.699 ± 0.425
0.0GlnCys: 0.0 ± 0.0
2.124GlnAsp: 2.124 ± 0.592
1.062GlnGlu: 1.062 ± 0.336
1.911GlnPhe: 1.911 ± 0.581
1.062GlnGly: 1.062 ± 0.565
1.274GlnHis: 1.274 ± 0.487
2.336GlnIle: 2.336 ± 0.697
2.973GlnLys: 2.973 ± 0.87
2.124GlnLeu: 2.124 ± 0.661
0.425GlnMet: 0.425 ± 0.25
2.973GlnAsn: 2.973 ± 1.187
1.487GlnPro: 1.487 ± 0.822
1.911GlnGln: 1.911 ± 1.374
0.425GlnArg: 0.425 ± 0.417
4.884GlnSer: 4.884 ± 1.301
2.761GlnThr: 2.761 ± 2.058
1.911GlnVal: 1.911 ± 0.729
0.0GlnTrp: 0.0 ± 0.0
1.274GlnTyr: 1.274 ± 0.48
0.0GlnXaa: 0.0 ± 0.0
Arg
2.761ArgAla: 2.761 ± 1.084
0.849ArgCys: 0.849 ± 0.508
1.274ArgAsp: 1.274 ± 0.8
1.487ArgGlu: 1.487 ± 0.407
1.062ArgPhe: 1.062 ± 0.475
2.548ArgGly: 2.548 ± 0.787
0.849ArgHis: 0.849 ± 0.33
1.911ArgIle: 1.911 ± 0.588
2.548ArgLys: 2.548 ± 1.218
3.822ArgLeu: 3.822 ± 1.29
0.425ArgMet: 0.425 ± 0.222
3.185ArgAsn: 3.185 ± 1.321
0.425ArgPro: 0.425 ± 0.26
2.124ArgGln: 2.124 ± 0.426
1.487ArgArg: 1.487 ± 0.437
3.185ArgSer: 3.185 ± 0.748
2.973ArgThr: 2.973 ± 0.791
1.699ArgVal: 1.699 ± 0.406
0.637ArgTrp: 0.637 ± 0.232
1.274ArgTyr: 1.274 ± 0.366
0.0ArgXaa: 0.0 ± 0.0
Ser
2.336SerAla: 2.336 ± 1.041
0.849SerCys: 0.849 ± 0.338
3.61SerAsp: 3.61 ± 1.126
4.46SerGlu: 4.46 ± 1.583
2.336SerPhe: 2.336 ± 0.614
2.761SerGly: 2.761 ± 0.474
0.849SerHis: 0.849 ± 0.407
8.07SerIle: 8.07 ± 1.393
6.158SerLys: 6.158 ± 1.042
10.618SerLeu: 10.618 ± 1.512
1.487SerMet: 1.487 ± 0.628
5.946SerAsn: 5.946 ± 1.531
3.398SerPro: 3.398 ± 1.089
2.761SerGln: 2.761 ± 1.815
3.822SerArg: 3.822 ± 0.412
5.521SerSer: 5.521 ± 1.035
8.07SerThr: 8.07 ± 2.602
5.309SerVal: 5.309 ± 1.845
0.425SerTrp: 0.425 ± 0.254
2.973SerTyr: 2.973 ± 0.749
0.0SerXaa: 0.0 ± 0.0
Thr
2.973ThrAla: 2.973 ± 1.399
1.699ThrCys: 1.699 ± 0.543
3.61ThrAsp: 3.61 ± 1.408
3.61ThrGlu: 3.61 ± 0.564
2.124ThrPhe: 2.124 ± 1.336
2.124ThrGly: 2.124 ± 0.632
2.336ThrHis: 2.336 ± 0.99
5.734ThrIle: 5.734 ± 0.832
5.946ThrLys: 5.946 ± 1.304
7.857ThrLeu: 7.857 ± 1.563
1.487ThrMet: 1.487 ± 0.465
5.309ThrAsn: 5.309 ± 0.868
3.822ThrPro: 3.822 ± 1.542
3.398ThrGln: 3.398 ± 2.078
2.336ThrArg: 2.336 ± 0.742
9.769ThrSer: 9.769 ± 2.65
8.07ThrThr: 8.07 ± 2.649
2.124ThrVal: 2.124 ± 0.724
0.637ThrTrp: 0.637 ± 0.381
3.822ThrTyr: 3.822 ± 1.029
0.0ThrXaa: 0.0 ± 0.0
Val
1.911ValAla: 1.911 ± 0.916
1.487ValCys: 1.487 ± 0.636
3.185ValAsp: 3.185 ± 0.865
1.487ValGlu: 1.487 ± 0.614
2.336ValPhe: 2.336 ± 0.509
2.761ValGly: 2.761 ± 0.773
0.849ValHis: 0.849 ± 0.323
6.583ValIle: 6.583 ± 1.761
2.336ValLys: 2.336 ± 0.843
7.008ValLeu: 7.008 ± 1.506
0.637ValMet: 0.637 ± 0.336
3.61ValAsn: 3.61 ± 1.263
1.062ValPro: 1.062 ± 0.661
2.124ValGln: 2.124 ± 0.694
2.336ValArg: 2.336 ± 0.51
3.185ValSer: 3.185 ± 1.649
1.911ValThr: 1.911 ± 0.66
3.61ValVal: 3.61 ± 1.102
0.212ValTrp: 0.212 ± 0.127
2.124ValTyr: 2.124 ± 1.022
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.212TrpCys: 0.212 ± 0.127
0.0TrpAsp: 0.0 ± 0.0
0.212TrpGlu: 0.212 ± 0.333
0.425TrpPhe: 0.425 ± 0.254
0.425TrpGly: 0.425 ± 0.203
0.212TrpHis: 0.212 ± 0.127
0.849TrpIle: 0.849 ± 0.508
1.062TrpLys: 1.062 ± 0.329
1.062TrpLeu: 1.062 ± 0.635
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.425TrpPro: 0.425 ± 0.321
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.637TrpSer: 0.637 ± 0.381
0.849TrpThr: 0.849 ± 0.355
0.849TrpVal: 0.849 ± 0.369
0.0TrpTrp: 0.0 ± 0.0
0.637TrpTyr: 0.637 ± 0.44
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.911TyrAla: 1.911 ± 0.674
1.062TyrCys: 1.062 ± 0.447
1.487TyrAsp: 1.487 ± 0.998
1.487TyrGlu: 1.487 ± 0.527
1.274TyrPhe: 1.274 ± 0.491
2.548TyrGly: 2.548 ± 0.618
1.911TyrHis: 1.911 ± 0.582
3.61TyrIle: 3.61 ± 0.472
2.548TyrLys: 2.548 ± 0.589
3.822TyrLeu: 3.822 ± 1.442
1.062TyrMet: 1.062 ± 0.475
4.672TyrAsn: 4.672 ± 1.363
1.911TyrPro: 1.911 ± 0.645
0.425TyrGln: 0.425 ± 0.329
2.548TyrArg: 2.548 ± 1.067
1.699TyrSer: 1.699 ± 0.449
3.185TyrThr: 3.185 ± 0.841
2.548TyrVal: 2.548 ± 0.934
0.425TyrTrp: 0.425 ± 0.228
1.699TyrTyr: 1.699 ± 0.554
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 12 proteins (4710 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski