Amino acid dipepetide frequency for Labrenzia sp. OB1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	14.266AlaAla: 14.266 ± 0.145	1.015AlaCys: 1.015 ± 0.027	6.625AlaAsp: 6.625 ± 0.066	7.316AlaGlu: 7.316 ± 0.071	4.381AlaPhe: 4.381 ± 0.047	10.135AlaGly: 10.135 ± 0.1	2.018AlaHis: 2.018 ± 0.038	5.891AlaIle: 5.891 ± 0.064	3.702AlaLys: 3.702 ± 0.063	12.001AlaLeu: 12.001 ± 0.109	3.22AlaMet: 3.22 ± 0.047	2.948AlaAsn: 2.948 ± 0.051	4.626AlaPro: 4.626 ± 0.067	3.465AlaGln: 3.465 ± 0.049	7.161AlaArg: 7.161 ± 0.081	6.096AlaSer: 6.096 ± 0.072	5.33AlaThr: 5.33 ± 0.065	8.38AlaVal: 8.38 ± 0.083	1.293AlaTrp: 1.293 ± 0.028	2.501AlaTyr: 2.501 ± 0.042	0.002AlaXaa: 0.002 ± 0.001
Cys	0.945CysAla: 0.945 ± 0.025	0.126CysCys: 0.126 ± 0.011	0.556CysAsp: 0.556 ± 0.024	0.507CysGlu: 0.507 ± 0.019	0.361CysPhe: 0.361 ± 0.014	1.003CysGly: 1.003 ± 0.026	0.226CysHis: 0.226 ± 0.012	0.423CysIle: 0.423 ± 0.018	0.255CysLys: 0.255 ± 0.013	0.95CysLeu: 0.95 ± 0.028	0.169CysMet: 0.169 ± 0.012	0.243CysAsn: 0.243 ± 0.013	0.44CysPro: 0.44 ± 0.016	0.279CysGln: 0.279 ± 0.016	0.585CysArg: 0.585 ± 0.022	0.488CysSer: 0.488 ± 0.019	0.404CysThr: 0.404 ± 0.017	0.633CysVal: 0.633 ± 0.021	0.111CysTrp: 0.111 ± 0.009	0.224CysTyr: 0.224 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	6.267AspAla: 6.267 ± 0.071	0.496AspCys: 0.496 ± 0.019	3.17AspAsp: 3.17 ± 0.061	3.548AspGlu: 3.548 ± 0.058	2.436AspPhe: 2.436 ± 0.043	5.274AspGly: 5.274 ± 0.106	1.252AspHis: 1.252 ± 0.033	3.488AspIle: 3.488 ± 0.05	1.988AspLys: 1.988 ± 0.039	6.682AspLeu: 6.682 ± 0.067	1.551AspMet: 1.551 ± 0.03	1.552AspAsn: 1.552 ± 0.037	3.519AspPro: 3.519 ± 0.052	1.81AspGln: 1.81 ± 0.032	4.125AspArg: 4.125 ± 0.06	2.388AspSer: 2.388 ± 0.046	3.042AspThr: 3.042 ± 0.065	4.283AspVal: 4.283 ± 0.055	1.026AspTrp: 1.026 ± 0.03	1.619AspTyr: 1.619 ± 0.03	0.0AspXaa: 0.0 ± 0.0
Glu	7.337GluAla: 7.337 ± 0.081	0.378GluCys: 0.378 ± 0.015	3.666GluAsp: 3.666 ± 0.051	3.892GluGlu: 3.892 ± 0.058	2.067GluPhe: 2.067 ± 0.036	4.506GluGly: 4.506 ± 0.056	1.17GluHis: 1.17 ± 0.028	4.0GluIle: 4.0 ± 0.055	2.87GluLys: 2.87 ± 0.055	5.792GluLeu: 5.792 ± 0.062	1.605GluMet: 1.605 ± 0.031	2.145GluAsn: 2.145 ± 0.038	2.644GluPro: 2.644 ± 0.048	2.131GluGln: 2.131 ± 0.042	4.301GluArg: 4.301 ± 0.054	2.472GluSer: 2.472 ± 0.037	4.336GluThr: 4.336 ± 0.057	4.057GluVal: 4.057 ± 0.057	0.648GluTrp: 0.648 ± 0.022	0.996GluTyr: 0.996 ± 0.027	0.0GluXaa: 0.0 ± 0.0
Phe	4.429PheAla: 4.429 ± 0.053	0.453PheCys: 0.453 ± 0.017	2.769PheAsp: 2.769 ± 0.048	2.478PheGlu: 2.478 ± 0.043	1.669PhePhe: 1.669 ± 0.033	3.763PheGly: 3.763 ± 0.06	0.788PheHis: 0.788 ± 0.025	1.848PheIle: 1.848 ± 0.036	1.266PheLys: 1.266 ± 0.026	3.978PheLeu: 3.978 ± 0.055	0.892PheMet: 0.892 ± 0.027	1.207PheAsn: 1.207 ± 0.028	1.693PhePro: 1.693 ± 0.035	1.249PheGln: 1.249 ± 0.029	2.229PheArg: 2.229 ± 0.046	2.638PheSer: 2.638 ± 0.042	2.141PheThr: 2.141 ± 0.039	2.929PheVal: 2.929 ± 0.051	0.572PheTrp: 0.572 ± 0.018	0.969PheTyr: 0.969 ± 0.026	0.0PheXaa: 0.0 ± 0.0
Gly	8.463GlyAla: 8.463 ± 0.087	0.888GlyCys: 0.888 ± 0.025	4.563GlyAsp: 4.563 ± 0.075	4.94GlyGlu: 4.94 ± 0.062	3.777GlyPhe: 3.777 ± 0.058	7.272GlyGly: 7.272 ± 0.157	1.854GlyHis: 1.854 ± 0.031	4.866GlyIle: 4.866 ± 0.053	3.633GlyLys: 3.633 ± 0.053	9.201GlyLeu: 9.201 ± 0.087	2.228GlyMet: 2.228 ± 0.037	2.443GlyAsn: 2.443 ± 0.065	3.351GlyPro: 3.351 ± 0.047	2.845GlyGln: 2.845 ± 0.04	5.332GlyArg: 5.332 ± 0.067	4.903GlySer: 4.903 ± 0.073	4.79GlyThr: 4.79 ± 0.078	5.921GlyVal: 5.921 ± 0.065	1.268GlyTrp: 1.268 ± 0.029	2.405GlyTyr: 2.405 ± 0.041	0.001GlyXaa: 0.001 ± 0.001
His	1.882HisAla: 1.882 ± 0.037	0.229HisCys: 0.229 ± 0.011	1.158HisAsp: 1.158 ± 0.028	1.127HisGlu: 1.127 ± 0.03	0.861HisPhe: 0.861 ± 0.023	1.828HisGly: 1.828 ± 0.039	0.53HisHis: 0.53 ± 0.02	0.986HisIle: 0.986 ± 0.021	0.61HisLys: 0.61 ± 0.018	2.078HisLeu: 2.078 ± 0.039	0.537HisMet: 0.537 ± 0.021	0.472HisAsn: 0.472 ± 0.018	1.256HisPro: 1.256 ± 0.028	0.641HisGln: 0.641 ± 0.02	1.216HisArg: 1.216 ± 0.032	0.985HisSer: 0.985 ± 0.027	0.832HisThr: 0.832 ± 0.025	1.463HisVal: 1.463 ± 0.032	0.299HisTrp: 0.299 ± 0.014	0.53HisTyr: 0.53 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	6.949IleAla: 6.949 ± 0.071	0.644IleCys: 0.644 ± 0.02	3.681IleAsp: 3.681 ± 0.052	3.578IleGlu: 3.578 ± 0.051	1.966IlePhe: 1.966 ± 0.039	5.181IleGly: 5.181 ± 0.067	0.979IleHis: 0.979 ± 0.027	2.385IleIle: 2.385 ± 0.046	1.566IleLys: 1.566 ± 0.033	5.169IleLeu: 5.169 ± 0.062	1.097IleMet: 1.097 ± 0.027	1.537IleAsn: 1.537 ± 0.033	2.411IlePro: 2.411 ± 0.037	1.386IleGln: 1.386 ± 0.032	3.417IleArg: 3.417 ± 0.038	3.444IleSer: 3.444 ± 0.051	2.835IleThr: 2.835 ± 0.038	4.314IleVal: 4.314 ± 0.058	0.679IleTrp: 0.679 ± 0.02	1.306IleTyr: 1.306 ± 0.026	0.001IleXaa: 0.001 ± 0.001
Lys	4.391LysAla: 4.391 ± 0.062	0.214LysCys: 0.214 ± 0.012	2.181LysAsp: 2.181 ± 0.04	1.983LysGlu: 1.983 ± 0.037	1.099LysPhe: 1.099 ± 0.029	2.792LysGly: 2.792 ± 0.045	0.66LysHis: 0.66 ± 0.022	2.146LysIle: 2.146 ± 0.039	1.528LysLys: 1.528 ± 0.04	3.604LysLeu: 3.604 ± 0.052	0.871LysMet: 0.871 ± 0.026	1.072LysAsn: 1.072 ± 0.03	2.016LysPro: 2.016 ± 0.041	1.132LysGln: 1.132 ± 0.027	2.432LysArg: 2.432 ± 0.04	2.315LysSer: 2.315 ± 0.041	2.357LysThr: 2.357 ± 0.039	2.749LysVal: 2.749 ± 0.044	0.407LysTrp: 0.407 ± 0.016	0.703LysTyr: 0.703 ± 0.025	0.001LysXaa: 0.001 ± 0.001
Leu	12.197LeuAla: 12.197 ± 0.125	0.973LeuCys: 0.973 ± 0.027	6.024LeuAsp: 6.024 ± 0.056	6.302LeuGlu: 6.302 ± 0.073	3.936LeuPhe: 3.936 ± 0.064	8.119LeuGly: 8.119 ± 0.073	1.766LeuHis: 1.766 ± 0.037	5.367LeuIle: 5.367 ± 0.062	4.384LeuLys: 4.384 ± 0.058	9.506LeuLeu: 9.506 ± 0.11	2.442LeuMet: 2.442 ± 0.036	3.032LeuAsn: 3.032 ± 0.039	5.371LeuPro: 5.371 ± 0.059	3.047LeuGln: 3.047 ± 0.043	6.036LeuArg: 6.036 ± 0.072	7.068LeuSer: 7.068 ± 0.077	5.841LeuThr: 5.841 ± 0.064	7.457LeuVal: 7.457 ± 0.073	1.112LeuTrp: 1.112 ± 0.026	2.147LeuTyr: 2.147 ± 0.04	0.001LeuXaa: 0.001 ± 0.001
Met	2.871MetAla: 2.871 ± 0.047	0.16MetCys: 0.16 ± 0.01	1.301MetAsp: 1.301 ± 0.033	1.314MetGlu: 1.314 ± 0.028	0.796MetPhe: 0.796 ± 0.024	1.801MetGly: 1.801 ± 0.035	0.442MetHis: 0.442 ± 0.018	1.549MetIle: 1.549 ± 0.035	1.141MetLys: 1.141 ± 0.029	2.404MetLeu: 2.404 ± 0.037	0.67MetMet: 0.67 ± 0.021	0.856MetAsn: 0.856 ± 0.022	1.437MetPro: 1.437 ± 0.029	0.794MetGln: 0.794 ± 0.024	1.663MetArg: 1.663 ± 0.031	1.865MetSer: 1.865 ± 0.034	1.92MetThr: 1.92 ± 0.033	1.727MetVal: 1.727 ± 0.037	0.203MetTrp: 0.203 ± 0.012	0.315MetTyr: 0.315 ± 0.014	0.002MetXaa: 0.002 ± 0.001
Asn	3.255AsnAla: 3.255 ± 0.054	0.269AsnCys: 0.269 ± 0.013	1.602AsnAsp: 1.602 ± 0.046	1.479AsnGlu: 1.479 ± 0.036	1.113AsnPhe: 1.113 ± 0.028	2.638AsnGly: 2.638 ± 0.053	0.512AsnHis: 0.512 ± 0.021	1.627AsnIle: 1.627 ± 0.034	0.908AsnLys: 0.908 ± 0.022	2.852AsnLeu: 2.852 ± 0.043	0.741AsnMet: 0.741 ± 0.023	0.822AsnAsn: 0.822 ± 0.027	1.901AsnPro: 1.901 ± 0.036	0.861AsnGln: 0.861 ± 0.025	1.973AsnArg: 1.973 ± 0.042	1.573AsnSer: 1.573 ± 0.035	1.439AsnThr: 1.439 ± 0.037	2.078AsnVal: 2.078 ± 0.037	0.472AsnTrp: 0.472 ± 0.017	0.749AsnTyr: 0.749 ± 0.024	0.001AsnXaa: 0.001 ± 0.001
Pro	5.309ProAla: 5.309 ± 0.071	0.325ProCys: 0.325 ± 0.015	3.835ProAsp: 3.835 ± 0.05	3.894ProGlu: 3.894 ± 0.052	2.106ProPhe: 2.106 ± 0.04	4.346ProGly: 4.346 ± 0.06	1.015ProHis: 1.015 ± 0.027	2.122ProIle: 2.122 ± 0.037	1.651ProLys: 1.651 ± 0.034	4.494ProLeu: 4.494 ± 0.064	1.073ProMet: 1.073 ± 0.029	1.299ProAsn: 1.299 ± 0.026	2.109ProPro: 2.109 ± 0.043	1.653ProGln: 1.653 ± 0.035	2.379ProArg: 2.379 ± 0.036	2.562ProSer: 2.562 ± 0.042	2.115ProThr: 2.115 ± 0.041	4.397ProVal: 4.397 ± 0.051	0.604ProTrp: 0.604 ± 0.023	1.145ProTyr: 1.145 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	3.744GlnAla: 3.744 ± 0.052	0.197GlnCys: 0.197 ± 0.012	1.813GlnAsp: 1.813 ± 0.037	1.815GlnGlu: 1.815 ± 0.037	1.112GlnPhe: 1.112 ± 0.028	2.316GlnGly: 2.316 ± 0.045	0.576GlnHis: 0.576 ± 0.021	2.062GlnIle: 2.062 ± 0.039	1.365GlnLys: 1.365 ± 0.032	2.861GlnLeu: 2.861 ± 0.045	0.916GlnMet: 0.916 ± 0.023	1.002GlnAsn: 1.002 ± 0.027	1.527GlnPro: 1.527 ± 0.031	1.195GlnGln: 1.195 ± 0.031	2.037GlnArg: 2.037 ± 0.045	2.016GlnSer: 2.016 ± 0.04	1.97GlnThr: 1.97 ± 0.034	2.321GlnVal: 2.321 ± 0.04	0.361GlnTrp: 0.361 ± 0.014	0.598GlnTyr: 0.598 ± 0.02	0.001GlnXaa: 0.001 ± 0.001
Arg	6.112ArgAla: 6.112 ± 0.069	0.509ArgCys: 0.509 ± 0.018	3.691ArgAsp: 3.691 ± 0.048	3.997ArgGlu: 3.997 ± 0.055	2.754ArgPhe: 2.754 ± 0.046	4.056ArgGly: 4.056 ± 0.061	1.497ArgHis: 1.497 ± 0.035	3.873ArgIle: 3.873 ± 0.056	2.811ArgLys: 2.811 ± 0.051	7.088ArgLeu: 7.088 ± 0.071	1.814ArgMet: 1.814 ± 0.033	1.908ArgAsn: 1.908 ± 0.034	2.95ArgPro: 2.95 ± 0.047	2.547ArgGln: 2.547 ± 0.045	4.517ArgArg: 4.517 ± 0.066	3.66ArgSer: 3.66 ± 0.049	3.304ArgThr: 3.304 ± 0.042	4.089ArgVal: 4.089 ± 0.06	0.758ArgTrp: 0.758 ± 0.025	1.511ArgTyr: 1.511 ± 0.035	0.001ArgXaa: 0.001 ± 0.001
Ser	6.192SerAla: 6.192 ± 0.069	0.485SerCys: 0.485 ± 0.019	3.479SerAsp: 3.479 ± 0.051	3.489SerGlu: 3.489 ± 0.048	2.564SerPhe: 2.564 ± 0.044	6.25SerGly: 6.25 ± 0.08	1.146SerHis: 1.146 ± 0.028	3.074SerIle: 3.074 ± 0.048	1.802SerLys: 1.802 ± 0.037	5.849SerLeu: 5.849 ± 0.069	1.431SerMet: 1.431 ± 0.032	1.649SerAsn: 1.649 ± 0.036	2.672SerPro: 2.672 ± 0.039	1.842SerGln: 1.842 ± 0.034	3.658SerArg: 3.658 ± 0.052	3.474SerSer: 3.474 ± 0.056	2.783SerThr: 2.783 ± 0.05	4.418SerVal: 4.418 ± 0.058	0.756SerTrp: 0.756 ± 0.023	1.421SerTyr: 1.421 ± 0.032	0.002SerXaa: 0.002 ± 0.001
Thr	6.128ThrAla: 6.128 ± 0.065	0.468ThrCys: 0.468 ± 0.019	3.059ThrAsp: 3.059 ± 0.058	2.904ThrGlu: 2.904 ± 0.045	2.225ThrPhe: 2.225 ± 0.038	5.582ThrGly: 5.582 ± 0.078	0.993ThrHis: 0.993 ± 0.027	2.998ThrIle: 2.998 ± 0.061	1.485ThrLys: 1.485 ± 0.033	5.946ThrLeu: 5.946 ± 0.067	1.204ThrMet: 1.204 ± 0.026	1.39ThrAsn: 1.39 ± 0.03	3.015ThrPro: 3.015 ± 0.041	1.503ThrGln: 1.503 ± 0.032	3.325ThrArg: 3.325 ± 0.045	3.152ThrSer: 3.152 ± 0.052	2.752ThrThr: 2.752 ± 0.069	4.608ThrVal: 4.608 ± 0.075	0.707ThrTrp: 0.707 ± 0.019	1.327ThrTyr: 1.327 ± 0.032	0.001ThrXaa: 0.001 ± 0.001
Val	8.196ValAla: 8.196 ± 0.077	0.681ValCys: 0.681 ± 0.02	4.15ValAsp: 4.15 ± 0.06	4.55ValGlu: 4.55 ± 0.051	3.183ValPhe: 3.183 ± 0.044	5.155ValGly: 5.155 ± 0.062	1.333ValHis: 1.333 ± 0.028	4.136ValIle: 4.136 ± 0.057	2.414ValLys: 2.414 ± 0.047	7.758ValLeu: 7.758 ± 0.083	1.917ValMet: 1.917 ± 0.04	2.153ValAsn: 2.153 ± 0.04	3.707ValPro: 3.707 ± 0.057	2.057ValGln: 2.057 ± 0.039	4.451ValArg: 4.451 ± 0.061	5.131ValSer: 5.131 ± 0.062	4.666ValThr: 4.666 ± 0.071	5.507ValVal: 5.507 ± 0.072	0.918ValTrp: 0.918 ± 0.026	1.623ValTyr: 1.623 ± 0.033	0.001ValXaa: 0.001 ± 0.001
Trp	1.122TrpAla: 1.122 ± 0.028	0.128TrpCys: 0.128 ± 0.009	0.675TrpAsp: 0.675 ± 0.023	0.547TrpGlu: 0.547 ± 0.018	0.539TrpPhe: 0.539 ± 0.02	0.864TrpGly: 0.864 ± 0.025	0.302TrpHis: 0.302 ± 0.014	0.694TrpIle: 0.694 ± 0.019	0.5TrpLys: 0.5 ± 0.018	1.481TrpLeu: 1.481 ± 0.033	0.368TrpMet: 0.368 ± 0.016	0.487TrpAsn: 0.487 ± 0.017	0.675TrpPro: 0.675 ± 0.019	0.581TrpGln: 0.581 ± 0.019	0.938TrpArg: 0.938 ± 0.022	0.846TrpSer: 0.846 ± 0.025	0.742TrpThr: 0.742 ± 0.023	0.765TrpVal: 0.765 ± 0.024	0.221TrpTrp: 0.221 ± 0.015	0.288TrpTyr: 0.288 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.317TyrAla: 2.317 ± 0.046	0.287TyrCys: 0.287 ± 0.015	1.515TyrAsp: 1.515 ± 0.03	1.353TyrGlu: 1.353 ± 0.034	1.012TyrPhe: 1.012 ± 0.025	2.062TyrGly: 2.062 ± 0.04	0.461TyrHis: 0.461 ± 0.017	0.988TyrIle: 0.988 ± 0.025	0.774TyrLys: 0.774 ± 0.021	2.435TyrLeu: 2.435 ± 0.041	0.481TyrMet: 0.481 ± 0.019	0.646TyrAsn: 0.646 ± 0.019	1.115TyrPro: 1.115 ± 0.025	0.79TyrGln: 0.79 ± 0.022	1.673TyrArg: 1.673 ± 0.036	1.355TyrSer: 1.355 ± 0.032	1.172TyrThr: 1.172 ± 0.028	1.59TyrVal: 1.59 ± 0.032	0.349TyrTrp: 0.349 ± 0.016	0.612TyrTyr: 0.612 ± 0.018	0.001TyrXaa: 0.001 ± 0.001
Xaa	0.001XaaAla: 0.001 ± 0.001	0.0XaaCys: 0.0 ± 0.0	0.002XaaAsp: 0.002 ± 0.001	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.002XaaIle: 0.002 ± 0.001	0.001XaaLys: 0.001 ± 0.001	0.001XaaLeu: 0.001 ± 0.001	0.001XaaMet: 0.001 ± 0.001	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.001	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.001	0.003XaaSer: 0.003 ± 0.001	0.001XaaThr: 0.001 ± 0.001	0.001XaaVal: 0.001 ± 0.001	0.001XaaTrp: 0.001 ± 0.001	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5016 proteins (1582622 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---