Amino acid dipepetide frequency for Kocuria soli

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.076AlaAla: 17.076 ± 0.226	0.768AlaCys: 0.768 ± 0.032	7.211AlaAsp: 7.211 ± 0.099	8.187AlaGlu: 8.187 ± 0.116	3.307AlaPhe: 3.307 ± 0.073	10.982AlaGly: 10.982 ± 0.132	2.536AlaHis: 2.536 ± 0.061	4.258AlaIle: 4.258 ± 0.088	2.819AlaLys: 2.819 ± 0.079	12.272AlaLeu: 12.272 ± 0.143	2.882AlaMet: 2.882 ± 0.055	2.268AlaAsn: 2.268 ± 0.058	5.893AlaPro: 5.893 ± 0.108	4.481AlaGln: 4.481 ± 0.072	8.101AlaArg: 8.101 ± 0.11	5.912AlaSer: 5.912 ± 0.088	6.95AlaThr: 6.95 ± 0.094	11.435AlaVal: 11.435 ± 0.136	1.857AlaTrp: 1.857 ± 0.052	2.019AlaTyr: 2.019 ± 0.053	0.0AlaXaa: 0.0 ± 0.0
Cys	0.759CysAla: 0.759 ± 0.033	0.068CysCys: 0.068 ± 0.01	0.358CysAsp: 0.358 ± 0.019	0.341CysGlu: 0.341 ± 0.024	0.209CysPhe: 0.209 ± 0.015	0.722CysGly: 0.722 ± 0.032	0.17CysHis: 0.17 ± 0.015	0.232CysIle: 0.232 ± 0.014	0.11CysLys: 0.11 ± 0.011	0.6CysLeu: 0.6 ± 0.029	0.111CysMet: 0.111 ± 0.012	0.139CysAsn: 0.139 ± 0.015	0.378CysPro: 0.378 ± 0.024	0.177CysGln: 0.177 ± 0.014	0.496CysArg: 0.496 ± 0.026	0.383CysSer: 0.383 ± 0.019	0.409CysThr: 0.409 ± 0.023	0.552CysVal: 0.552 ± 0.025	0.091CysTrp: 0.091 ± 0.012	0.136CysTyr: 0.136 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	7.17AspAla: 7.17 ± 0.102	0.297AspCys: 0.297 ± 0.02	4.327AspAsp: 4.327 ± 0.083	3.909AspGlu: 3.909 ± 0.084	1.685AspPhe: 1.685 ± 0.045	6.134AspGly: 6.134 ± 0.097	1.493AspHis: 1.493 ± 0.045	1.987AspIle: 1.987 ± 0.059	1.22AspLys: 1.22 ± 0.043	6.791AspLeu: 6.791 ± 0.103	1.046AspMet: 1.046 ± 0.03	1.004AspAsn: 1.004 ± 0.037	4.604AspPro: 4.604 ± 0.076	2.295AspGln: 2.295 ± 0.054	4.754AspArg: 4.754 ± 0.085	3.232AspSer: 3.232 ± 0.069	3.048AspThr: 3.048 ± 0.063	5.382AspVal: 5.382 ± 0.089	0.883AspTrp: 0.883 ± 0.034	1.245AspTyr: 1.245 ± 0.042	0.0AspXaa: 0.0 ± 0.0
Glu	7.569GluAla: 7.569 ± 0.109	0.33GluCys: 0.33 ± 0.019	3.908GluAsp: 3.908 ± 0.075	3.684GluGlu: 3.684 ± 0.076	1.815GluPhe: 1.815 ± 0.043	4.39GluGly: 4.39 ± 0.087	1.899GluHis: 1.899 ± 0.052	3.059GluIle: 3.059 ± 0.066	1.596GluLys: 1.596 ± 0.049	6.597GluLeu: 6.597 ± 0.102	1.098GluMet: 1.098 ± 0.038	1.611GluAsn: 1.611 ± 0.056	3.289GluPro: 3.289 ± 0.067	2.752GluGln: 2.752 ± 0.056	4.899GluArg: 4.899 ± 0.085	3.552GluSer: 3.552 ± 0.07	3.271GluThr: 3.271 ± 0.068	5.017GluVal: 5.017 ± 0.078	0.832GluTrp: 0.832 ± 0.028	1.167GluTyr: 1.167 ± 0.039	0.0GluXaa: 0.0 ± 0.0
Phe	3.358PheAla: 3.358 ± 0.076	0.205PheCys: 0.205 ± 0.017	2.093PheAsp: 2.093 ± 0.051	1.695PheGlu: 1.695 ± 0.045	1.021PhePhe: 1.021 ± 0.041	3.062PheGly: 3.062 ± 0.071	0.636PheHis: 0.636 ± 0.028	1.014PheIle: 1.014 ± 0.038	0.625PheLys: 0.625 ± 0.026	2.83PheLeu: 2.83 ± 0.073	0.607PheMet: 0.607 ± 0.026	0.728PheAsn: 0.728 ± 0.029	1.389PhePro: 1.389 ± 0.041	0.779PheGln: 0.779 ± 0.031	1.802PheArg: 1.802 ± 0.046	1.658PheSer: 1.658 ± 0.047	2.025PheThr: 2.025 ± 0.056	2.582PheVal: 2.582 ± 0.06	0.457PheTrp: 0.457 ± 0.027	0.652PheTyr: 0.652 ± 0.03	0.0PheXaa: 0.0 ± 0.0
Gly	10.101GlyAla: 10.101 ± 0.141	0.642GlyCys: 0.642 ± 0.029	4.8GlyAsp: 4.8 ± 0.076	5.129GlyGlu: 5.129 ± 0.096	2.921GlyPhe: 2.921 ± 0.071	7.434GlyGly: 7.434 ± 0.128	2.162GlyHis: 2.162 ± 0.049	3.856GlyIle: 3.856 ± 0.073	2.5GlyLys: 2.5 ± 0.061	9.03GlyLeu: 9.03 ± 0.118	2.091GlyMet: 2.091 ± 0.049	1.976GlyAsn: 1.976 ± 0.051	4.311GlyPro: 4.311 ± 0.078	3.285GlyGln: 3.285 ± 0.061	6.313GlyArg: 6.313 ± 0.093	5.697GlySer: 5.697 ± 0.09	5.666GlyThr: 5.666 ± 0.087	7.554GlyVal: 7.554 ± 0.109	1.618GlyTrp: 1.618 ± 0.051	2.074GlyTyr: 2.074 ± 0.053	0.0GlyXaa: 0.0 ± 0.0
His	2.213HisAla: 2.213 ± 0.046	0.176HisCys: 0.176 ± 0.012	1.468HisAsp: 1.468 ± 0.046	1.287HisGlu: 1.287 ± 0.037	0.608HisPhe: 0.608 ± 0.026	2.273HisGly: 2.273 ± 0.057	0.675HisHis: 0.675 ± 0.027	0.672HisIle: 0.672 ± 0.026	0.449HisLys: 0.449 ± 0.025	2.352HisLeu: 2.352 ± 0.06	0.398HisMet: 0.398 ± 0.022	0.446HisAsn: 0.446 ± 0.023	1.637HisPro: 1.637 ± 0.042	0.742HisGln: 0.742 ± 0.027	1.962HisArg: 1.962 ± 0.054	1.179HisSer: 1.179 ± 0.039	1.193HisThr: 1.193 ± 0.036	1.868HisVal: 1.868 ± 0.051	0.351HisTrp: 0.351 ± 0.021	0.449HisTyr: 0.449 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	5.098IleAla: 5.098 ± 0.09	0.297IleCys: 0.297 ± 0.018	2.735IleAsp: 2.735 ± 0.06	2.417IleGlu: 2.417 ± 0.057	1.162IlePhe: 1.162 ± 0.045	3.997IleGly: 3.997 ± 0.085	0.793IleHis: 0.793 ± 0.033	1.367IleIle: 1.367 ± 0.039	0.905IleLys: 0.905 ± 0.037	3.467IleLeu: 3.467 ± 0.078	0.807IleMet: 0.807 ± 0.034	0.958IleAsn: 0.958 ± 0.039	2.143IlePro: 2.143 ± 0.052	1.149IleGln: 1.149 ± 0.037	2.589IleArg: 2.589 ± 0.051	2.236IleSer: 2.236 ± 0.05	2.652IleThr: 2.652 ± 0.057	3.39IleVal: 3.39 ± 0.064	0.434IleTrp: 0.434 ± 0.021	0.701IleTyr: 0.701 ± 0.033	0.0IleXaa: 0.0 ± 0.0
Lys	2.891LysAla: 2.891 ± 0.059	0.107LysCys: 0.107 ± 0.011	1.596LysAsp: 1.596 ± 0.044	1.307LysGlu: 1.307 ± 0.046	0.624LysPhe: 0.624 ± 0.025	1.815LysGly: 1.815 ± 0.053	0.526LysHis: 0.526 ± 0.026	1.168LysIle: 1.168 ± 0.045	0.924LysLys: 0.924 ± 0.048	2.091LysLeu: 2.091 ± 0.058	0.486LysMet: 0.486 ± 0.024	0.666LysAsn: 0.666 ± 0.032	1.231LysPro: 1.231 ± 0.043	0.763LysGln: 0.763 ± 0.027	1.576LysArg: 1.576 ± 0.044	1.324LysSer: 1.324 ± 0.047	1.436LysThr: 1.436 ± 0.039	2.08LysVal: 2.08 ± 0.053	0.271LysTrp: 0.271 ± 0.018	0.499LysTyr: 0.499 ± 0.028	0.0LysXaa: 0.0 ± 0.0
Leu	12.484LeuAla: 12.484 ± 0.145	0.712LeuCys: 0.712 ± 0.028	6.379LeuAsp: 6.379 ± 0.087	5.788LeuGlu: 5.788 ± 0.095	2.654LeuPhe: 2.654 ± 0.067	9.024LeuGly: 9.024 ± 0.119	2.045LeuHis: 2.045 ± 0.051	4.027LeuIle: 4.027 ± 0.084	2.261LeuLys: 2.261 ± 0.056	9.485LeuLeu: 9.485 ± 0.138	1.942LeuMet: 1.942 ± 0.048	2.166LeuAsn: 2.166 ± 0.055	5.568LeuPro: 5.568 ± 0.089	2.637LeuGln: 2.637 ± 0.057	7.066LeuArg: 7.066 ± 0.098	5.737LeuSer: 5.737 ± 0.088	6.35LeuThr: 6.35 ± 0.082	8.879LeuVal: 8.879 ± 0.106	1.28LeuTrp: 1.28 ± 0.046	1.657LeuTyr: 1.657 ± 0.044	0.0LeuXaa: 0.0 ± 0.0
Met	2.55MetAla: 2.55 ± 0.059	0.143MetCys: 0.143 ± 0.012	1.104MetAsp: 1.104 ± 0.036	0.933MetGlu: 0.933 ± 0.042	0.609MetPhe: 0.609 ± 0.029	1.767MetGly: 1.767 ± 0.05	0.395MetHis: 0.395 ± 0.02	0.964MetIle: 0.964 ± 0.037	0.493MetLys: 0.493 ± 0.024	1.955MetLeu: 1.955 ± 0.054	0.406MetMet: 0.406 ± 0.024	0.579MetAsn: 0.579 ± 0.026	1.151MetPro: 1.151 ± 0.036	0.646MetGln: 0.646 ± 0.028	1.339MetArg: 1.339 ± 0.039	1.585MetSer: 1.585 ± 0.039	1.846MetThr: 1.846 ± 0.046	1.708MetVal: 1.708 ± 0.05	0.236MetTrp: 0.236 ± 0.019	0.328MetTyr: 0.328 ± 0.02	0.0MetXaa: 0.0 ± 0.0
Asn	2.526AsnAla: 2.526 ± 0.057	0.153AsnCys: 0.153 ± 0.015	1.338AsnAsp: 1.338 ± 0.043	1.072AsnGlu: 1.072 ± 0.036	0.68AsnPhe: 0.68 ± 0.031	2.049AsnGly: 2.049 ± 0.052	0.524AsnHis: 0.524 ± 0.023	0.874AsnIle: 0.874 ± 0.031	0.511AsnLys: 0.511 ± 0.027	2.096AsnLeu: 2.096 ± 0.052	0.462AsnMet: 0.462 ± 0.025	0.517AsnAsn: 0.517 ± 0.028	1.696AsnPro: 1.696 ± 0.048	0.79AsnGln: 0.79 ± 0.031	1.522AsnArg: 1.522 ± 0.041	1.217AsnSer: 1.217 ± 0.041	1.381AsnThr: 1.381 ± 0.045	1.748AsnVal: 1.748 ± 0.048	0.377AsnTrp: 0.377 ± 0.022	0.518AsnTyr: 0.518 ± 0.026	0.0AsnXaa: 0.0 ± 0.0
Pro	6.437ProAla: 6.437 ± 0.107	0.264ProCys: 0.264 ± 0.02	3.878ProAsp: 3.878 ± 0.077	4.978ProGlu: 4.978 ± 0.078	1.514ProPhe: 1.514 ± 0.045	5.416ProGly: 5.416 ± 0.088	1.17ProHis: 1.17 ± 0.038	1.604ProIle: 1.604 ± 0.048	1.26ProLys: 1.26 ± 0.04	4.559ProLeu: 4.559 ± 0.082	1.018ProMet: 1.018 ± 0.037	1.202ProAsn: 1.202 ± 0.037	2.184ProPro: 2.184 ± 0.062	1.912ProGln: 1.912 ± 0.05	3.361ProArg: 3.361 ± 0.077	3.367ProSer: 3.367 ± 0.074	3.464ProThr: 3.464 ± 0.073	5.412ProVal: 5.412 ± 0.093	0.937ProTrp: 0.937 ± 0.033	1.024ProTyr: 1.024 ± 0.04	0.0ProXaa: 0.0 ± 0.0
Gln	4.209GlnAla: 4.209 ± 0.08	0.153GlnCys: 0.153 ± 0.013	2.159GlnAsp: 2.159 ± 0.053	2.201GlnGlu: 2.201 ± 0.057	0.904GlnPhe: 0.904 ± 0.035	2.537GlnGly: 2.537 ± 0.054	0.738GlnHis: 0.738 ± 0.029	1.562GlnIle: 1.562 ± 0.045	0.845GlnLys: 0.845 ± 0.036	3.32GlnLeu: 3.32 ± 0.065	0.666GlnMet: 0.666 ± 0.026	0.825GlnAsn: 0.825 ± 0.034	1.799GlnPro: 1.799 ± 0.045	1.417GlnGln: 1.417 ± 0.045	2.864GlnArg: 2.864 ± 0.057	1.718GlnSer: 1.718 ± 0.042	1.686GlnThr: 1.686 ± 0.047	2.773GlnVal: 2.773 ± 0.054	0.572GlnTrp: 0.572 ± 0.026	0.679GlnTyr: 0.679 ± 0.032	0.0GlnXaa: 0.0 ± 0.0
Arg	7.893ArgAla: 7.893 ± 0.117	0.489ArgCys: 0.489 ± 0.027	4.056ArgAsp: 4.056 ± 0.071	4.713ArgGlu: 4.713 ± 0.087	2.164ArgPhe: 2.164 ± 0.052	5.315ArgGly: 5.315 ± 0.094	1.612ArgHis: 1.612 ± 0.048	3.164ArgIle: 3.164 ± 0.062	1.71ArgLys: 1.71 ± 0.051	6.748ArgLeu: 6.748 ± 0.115	1.776ArgMet: 1.776 ± 0.043	1.637ArgAsn: 1.637 ± 0.047	3.9ArgPro: 3.9 ± 0.085	2.392ArgGln: 2.392 ± 0.047	6.374ArgArg: 6.374 ± 0.113	4.319ArgSer: 4.319 ± 0.082	4.599ArgThr: 4.599 ± 0.072	5.505ArgVal: 5.505 ± 0.079	1.324ArgTrp: 1.324 ± 0.046	1.496ArgTyr: 1.496 ± 0.044	0.0ArgXaa: 0.0 ± 0.0
Ser	6.808SerAla: 6.808 ± 0.098	0.369SerCys: 0.369 ± 0.023	3.023SerAsp: 3.023 ± 0.057	3.39SerGlu: 3.39 ± 0.07	1.636SerPhe: 1.636 ± 0.041	5.918SerGly: 5.918 ± 0.083	1.1SerHis: 1.1 ± 0.039	2.081SerIle: 2.081 ± 0.057	1.289SerLys: 1.289 ± 0.042	5.108SerLeu: 5.108 ± 0.072	1.421SerMet: 1.421 ± 0.044	1.189SerAsn: 1.189 ± 0.04	3.23SerPro: 3.23 ± 0.062	1.812SerGln: 1.812 ± 0.042	3.901SerArg: 3.901 ± 0.081	3.638SerSer: 3.638 ± 0.095	4.09SerThr: 4.09 ± 0.074	5.048SerVal: 5.048 ± 0.088	0.908SerTrp: 0.908 ± 0.035	1.175SerTyr: 1.175 ± 0.039	0.0SerXaa: 0.0 ± 0.0
Thr	7.596ThrAla: 7.596 ± 0.107	0.404ThrCys: 0.404 ± 0.022	3.969ThrAsp: 3.969 ± 0.062	3.712ThrGlu: 3.712 ± 0.076	1.732ThrPhe: 1.732 ± 0.049	6.222ThrGly: 6.222 ± 0.096	1.303ThrHis: 1.303 ± 0.035	2.232ThrIle: 2.232 ± 0.058	1.31ThrLys: 1.31 ± 0.045	5.301ThrLeu: 5.301 ± 0.073	1.114ThrMet: 1.114 ± 0.032	1.308ThrAsn: 1.308 ± 0.038	3.897ThrPro: 3.897 ± 0.072	1.82ThrGln: 1.82 ± 0.045	3.804ThrArg: 3.804 ± 0.074	3.538ThrSer: 3.538 ± 0.059	4.028ThrThr: 4.028 ± 0.08	6.346ThrVal: 6.346 ± 0.085	0.979ThrTrp: 0.979 ± 0.035	1.256ThrTyr: 1.256 ± 0.038	0.0ThrXaa: 0.0 ± 0.0
Val	10.664ValAla: 10.664 ± 0.098	0.618ValCys: 0.618 ± 0.026	5.881ValAsp: 5.881 ± 0.086	5.649ValGlu: 5.649 ± 0.088	2.729ValPhe: 2.729 ± 0.058	7.121ValGly: 7.121 ± 0.102	1.961ValHis: 1.961 ± 0.055	3.884ValIle: 3.884 ± 0.076	1.794ValLys: 1.794 ± 0.057	9.869ValLeu: 9.869 ± 0.138	1.737ValMet: 1.737 ± 0.053	1.987ValAsn: 1.987 ± 0.045	4.861ValPro: 4.861 ± 0.09	2.55ValGln: 2.55 ± 0.054	5.806ValArg: 5.806 ± 0.099	4.795ValSer: 4.795 ± 0.078	5.783ValThr: 5.783 ± 0.077	9.624ValVal: 9.624 ± 0.133	1.081ValTrp: 1.081 ± 0.038	1.461ValTyr: 1.461 ± 0.043	0.0ValXaa: 0.0 ± 0.0
Trp	1.728TrpAla: 1.728 ± 0.049	0.112TrpCys: 0.112 ± 0.01	0.855TrpAsp: 0.855 ± 0.03	0.799TrpGlu: 0.799 ± 0.033	0.569TrpPhe: 0.569 ± 0.026	1.122TrpGly: 1.122 ± 0.038	0.33TrpHis: 0.33 ± 0.018	0.722TrpIle: 0.722 ± 0.032	0.325TrpLys: 0.325 ± 0.018	1.711TrpLeu: 1.711 ± 0.053	0.339TrpMet: 0.339 ± 0.024	0.387TrpAsn: 0.387 ± 0.022	0.749TrpPro: 0.749 ± 0.032	0.575TrpGln: 0.575 ± 0.024	1.08TrpArg: 1.08 ± 0.037	0.966TrpSer: 0.966 ± 0.037	0.924TrpThr: 0.924 ± 0.033	1.235TrpVal: 1.235 ± 0.038	0.385TrpTrp: 0.385 ± 0.021	0.292TrpTyr: 0.292 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.082TyrAla: 2.082 ± 0.045	0.134TyrCys: 0.134 ± 0.012	1.37TyrAsp: 1.37 ± 0.039	1.143TyrGlu: 1.143 ± 0.039	0.675TyrPhe: 0.675 ± 0.034	1.857TyrGly: 1.857 ± 0.057	0.327TyrHis: 0.327 ± 0.022	0.573TyrIle: 0.573 ± 0.025	0.434TyrLys: 0.434 ± 0.022	1.96TyrLeu: 1.96 ± 0.052	0.33TyrMet: 0.33 ± 0.022	0.458TyrAsn: 0.458 ± 0.029	1.051TyrPro: 1.051 ± 0.039	0.656TyrGln: 0.656 ± 0.03	1.575TyrArg: 1.575 ± 0.047	1.079TyrSer: 1.079 ± 0.038	1.07TyrThr: 1.07 ± 0.038	1.717TyrVal: 1.717 ± 0.048	0.336TyrTrp: 0.336 ± 0.019	0.44TyrTyr: 0.44 ± 0.024	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2527 proteins (857169 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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