Amino acid dipepetide frequency for Albibacterium bauzanense

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.237AlaAla: 5.237 ± 0.102	0.628AlaCys: 0.628 ± 0.029	3.796AlaAsp: 3.796 ± 0.069	4.216AlaGlu: 4.216 ± 0.072	3.382AlaPhe: 3.382 ± 0.062	4.849AlaGly: 4.849 ± 0.083	1.158AlaHis: 1.158 ± 0.044	5.924AlaIle: 5.924 ± 0.094	4.444AlaLys: 4.444 ± 0.081	6.837AlaLeu: 6.837 ± 0.107	1.664AlaMet: 1.664 ± 0.045	3.542AlaAsn: 3.542 ± 0.067	2.034AlaPro: 2.034 ± 0.05	2.602AlaGln: 2.602 ± 0.05	2.376AlaArg: 2.376 ± 0.056	4.671AlaSer: 4.671 ± 0.078	3.474AlaThr: 3.474 ± 0.062	4.244AlaVal: 4.244 ± 0.076	0.752AlaTrp: 0.752 ± 0.027	2.533AlaTyr: 2.533 ± 0.06	0.0AlaXaa: 0.0 ± 0.0
Cys	0.471CysAla: 0.471 ± 0.024	0.104CysCys: 0.104 ± 0.01	0.386CysAsp: 0.386 ± 0.022	0.382CysGlu: 0.382 ± 0.021	0.339CysPhe: 0.339 ± 0.018	0.583CysGly: 0.583 ± 0.025	0.203CysHis: 0.203 ± 0.017	0.594CysIle: 0.594 ± 0.03	0.423CysLys: 0.423 ± 0.022	0.662CysLeu: 0.662 ± 0.027	0.147CysMet: 0.147 ± 0.012	0.363CysAsn: 0.363 ± 0.02	0.306CysPro: 0.306 ± 0.023	0.193CysGln: 0.193 ± 0.013	0.273CysArg: 0.273 ± 0.018	0.488CysSer: 0.488 ± 0.023	0.417CysThr: 0.417 ± 0.023	0.395CysVal: 0.395 ± 0.022	0.065CysTrp: 0.065 ± 0.008	0.258CysTyr: 0.258 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	3.571AspAla: 3.571 ± 0.074	0.342AspCys: 0.342 ± 0.02	2.523AspAsp: 2.523 ± 0.056	3.589AspGlu: 3.589 ± 0.062	3.204AspPhe: 3.204 ± 0.061	3.5AspGly: 3.5 ± 0.072	0.978AspHis: 0.978 ± 0.032	4.562AspIle: 4.562 ± 0.074	3.921AspLys: 3.921 ± 0.073	5.48AspLeu: 5.48 ± 0.09	1.174AspMet: 1.174 ± 0.04	2.779AspAsn: 2.779 ± 0.056	2.036AspPro: 2.036 ± 0.045	1.964AspGln: 1.964 ± 0.048	2.247AspArg: 2.247 ± 0.044	3.334AspSer: 3.334 ± 0.073	2.517AspThr: 2.517 ± 0.063	3.32AspVal: 3.32 ± 0.056	0.725AspTrp: 0.725 ± 0.028	2.474AspTyr: 2.474 ± 0.06	0.0AspXaa: 0.0 ± 0.0
Glu	4.413GluAla: 4.413 ± 0.083	0.327GluCys: 0.327 ± 0.02	3.284GluAsp: 3.284 ± 0.07	4.768GluGlu: 4.768 ± 0.098	2.753GluPhe: 2.753 ± 0.055	3.795GluGly: 3.795 ± 0.061	1.123GluHis: 1.123 ± 0.035	5.318GluIle: 5.318 ± 0.084	5.106GluLys: 5.106 ± 0.094	6.194GluLeu: 6.194 ± 0.086	1.568GluMet: 1.568 ± 0.042	4.077GluAsn: 4.077 ± 0.075	1.743GluPro: 1.743 ± 0.044	2.375GluGln: 2.375 ± 0.057	2.851GluArg: 2.851 ± 0.066	3.788GluSer: 3.788 ± 0.067	3.178GluThr: 3.178 ± 0.054	4.085GluVal: 4.085 ± 0.066	0.747GluTrp: 0.747 ± 0.03	2.34GluTyr: 2.34 ± 0.049	0.0GluXaa: 0.0 ± 0.0
Phe	3.215PheAla: 3.215 ± 0.06	0.397PheCys: 0.397 ± 0.019	2.902PheAsp: 2.902 ± 0.055	2.948PheGlu: 2.948 ± 0.059	2.614PhePhe: 2.614 ± 0.064	3.481PheGly: 3.481 ± 0.063	0.871PheHis: 0.871 ± 0.029	4.085PheIle: 4.085 ± 0.081	3.288PheLys: 3.288 ± 0.058	4.713PheLeu: 4.713 ± 0.081	1.156PheMet: 1.156 ± 0.036	3.026PheAsn: 3.026 ± 0.059	1.738PhePro: 1.738 ± 0.044	1.657PheGln: 1.657 ± 0.042	1.784PheArg: 1.784 ± 0.041	3.809PheSer: 3.809 ± 0.069	2.739PheThr: 2.739 ± 0.049	2.895PheVal: 2.895 ± 0.059	0.553PheTrp: 0.553 ± 0.028	2.041PheTyr: 2.041 ± 0.045	0.0PheXaa: 0.0 ± 0.0
Gly	4.386GlyAla: 4.386 ± 0.078	0.544GlyCys: 0.544 ± 0.027	3.48GlyAsp: 3.48 ± 0.074	3.684GlyGlu: 3.684 ± 0.059	3.562GlyPhe: 3.562 ± 0.069	4.757GlyGly: 4.757 ± 0.101	1.163GlyHis: 1.163 ± 0.043	5.843GlyIle: 5.843 ± 0.082	5.013GlyLys: 5.013 ± 0.07	6.314GlyLeu: 6.314 ± 0.091	1.696GlyMet: 1.696 ± 0.04	3.546GlyAsn: 3.546 ± 0.071	1.547GlyPro: 1.547 ± 0.048	2.006GlyGln: 2.006 ± 0.052	2.474GlyArg: 2.474 ± 0.056	4.479GlySer: 4.479 ± 0.072	3.824GlyThr: 3.824 ± 0.074	4.415GlyVal: 4.415 ± 0.08	0.814GlyTrp: 0.814 ± 0.032	2.897GlyTyr: 2.897 ± 0.055	0.0GlyXaa: 0.0 ± 0.0
His	1.067HisAla: 1.067 ± 0.036	0.205HisCys: 0.205 ± 0.013	0.857HisAsp: 0.857 ± 0.032	0.997HisGlu: 0.997 ± 0.033	1.062HisPhe: 1.062 ± 0.034	1.158HisGly: 1.158 ± 0.038	0.473HisHis: 0.473 ± 0.026	1.492HisIle: 1.492 ± 0.042	0.957HisLys: 0.957 ± 0.033	1.807HisLeu: 1.807 ± 0.044	0.35HisMet: 0.35 ± 0.021	0.916HisAsn: 0.916 ± 0.031	0.994HisPro: 0.994 ± 0.034	0.775HisGln: 0.775 ± 0.03	0.752HisArg: 0.752 ± 0.033	1.218HisSer: 1.218 ± 0.038	0.944HisThr: 0.944 ± 0.03	0.972HisVal: 0.972 ± 0.035	0.228HisTrp: 0.228 ± 0.016	0.823HisTyr: 0.823 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	6.235IleAla: 6.235 ± 0.092	0.676IleCys: 0.676 ± 0.03	4.809IleAsp: 4.809 ± 0.071	5.47IleGlu: 5.47 ± 0.084	3.523IlePhe: 3.523 ± 0.069	5.459IleGly: 5.459 ± 0.084	1.488IleHis: 1.488 ± 0.045	6.473IleIle: 6.473 ± 0.101	5.628IleLys: 5.628 ± 0.085	7.435IleLeu: 7.435 ± 0.115	1.638IleMet: 1.638 ± 0.043	4.719IleAsn: 4.719 ± 0.09	3.482IlePro: 3.482 ± 0.068	2.997IleGln: 2.997 ± 0.061	3.149IleArg: 3.149 ± 0.057	5.915IleSer: 5.915 ± 0.079	4.452IleThr: 4.452 ± 0.071	4.841IleVal: 4.841 ± 0.078	0.724IleTrp: 0.724 ± 0.027	2.845IleTyr: 2.845 ± 0.058	0.0IleXaa: 0.0 ± 0.0
Lys	4.865LysAla: 4.865 ± 0.088	0.279LysCys: 0.279 ± 0.019	4.206LysAsp: 4.206 ± 0.08	5.548LysGlu: 5.548 ± 0.084	2.514LysPhe: 2.514 ± 0.045	4.361LysGly: 4.361 ± 0.073	1.288LysHis: 1.288 ± 0.038	5.378LysIle: 5.378 ± 0.08	5.3LysLys: 5.3 ± 0.097	6.114LysLeu: 6.114 ± 0.093	1.802LysMet: 1.802 ± 0.048	4.174LysAsn: 4.174 ± 0.073	2.555LysPro: 2.555 ± 0.057	2.628LysGln: 2.628 ± 0.058	2.901LysArg: 2.901 ± 0.059	4.162LysSer: 4.162 ± 0.071	3.807LysThr: 3.807 ± 0.069	4.452LysVal: 4.452 ± 0.068	0.736LysTrp: 0.736 ± 0.03	2.667LysTyr: 2.667 ± 0.054	0.0LysXaa: 0.0 ± 0.0
Leu	6.6LeuAla: 6.6 ± 0.085	0.709LeuCys: 0.709 ± 0.033	4.992LeuAsp: 4.992 ± 0.08	5.711LeuGlu: 5.711 ± 0.081	4.984LeuPhe: 4.984 ± 0.086	6.02LeuGly: 6.02 ± 0.094	1.622LeuHis: 1.622 ± 0.053	8.004LeuIle: 8.004 ± 0.118	7.423LeuLys: 7.423 ± 0.113	9.635LeuLeu: 9.635 ± 0.149	2.164LeuMet: 2.164 ± 0.053	5.89LeuAsn: 5.89 ± 0.09	3.886LeuPro: 3.886 ± 0.073	3.494LeuGln: 3.494 ± 0.061	3.704LeuArg: 3.704 ± 0.07	7.495LeuSer: 7.495 ± 0.099	5.017LeuThr: 5.017 ± 0.067	5.356LeuVal: 5.356 ± 0.076	0.863LeuTrp: 0.863 ± 0.03	3.23LeuTyr: 3.23 ± 0.068	0.0LeuXaa: 0.0 ± 0.0
Met	1.735MetAla: 1.735 ± 0.044	0.107MetCys: 0.107 ± 0.011	1.305MetAsp: 1.305 ± 0.045	1.517MetGlu: 1.517 ± 0.035	0.863MetPhe: 0.863 ± 0.03	1.639MetGly: 1.639 ± 0.04	0.428MetHis: 0.428 ± 0.021	1.667MetIle: 1.667 ± 0.043	1.956MetLys: 1.956 ± 0.045	2.054MetLeu: 2.054 ± 0.049	0.592MetMet: 0.592 ± 0.032	1.351MetAsn: 1.351 ± 0.035	1.0MetPro: 1.0 ± 0.036	0.884MetGln: 0.884 ± 0.032	1.026MetArg: 1.026 ± 0.032	1.298MetSer: 1.298 ± 0.042	1.11MetThr: 1.11 ± 0.038	1.395MetVal: 1.395 ± 0.042	0.195MetTrp: 0.195 ± 0.015	0.608MetTyr: 0.608 ± 0.031	0.0MetXaa: 0.0 ± 0.0
Asn	3.783AsnAla: 3.783 ± 0.074	0.348AsnCys: 0.348 ± 0.018	3.017AsnAsp: 3.017 ± 0.062	3.519AsnGlu: 3.519 ± 0.062	2.694AsnPhe: 2.694 ± 0.052	3.608AsnGly: 3.608 ± 0.071	1.038AsnHis: 1.038 ± 0.037	4.626AsnIle: 4.626 ± 0.08	3.86AsnLys: 3.86 ± 0.076	5.277AsnLeu: 5.277 ± 0.077	1.266AsnMet: 1.266 ± 0.031	3.582AsnAsn: 3.582 ± 0.069	2.671AsnPro: 2.671 ± 0.056	2.215AsnGln: 2.215 ± 0.053	2.407AsnArg: 2.407 ± 0.051	3.806AsnSer: 3.806 ± 0.067	3.215AsnThr: 3.215 ± 0.062	3.149AsnVal: 3.149 ± 0.061	0.704AsnTrp: 0.704 ± 0.03	2.565AsnTyr: 2.565 ± 0.062	0.0AsnXaa: 0.0 ± 0.0
Pro	2.466ProAla: 2.466 ± 0.062	0.22ProCys: 0.22 ± 0.014	2.403ProAsp: 2.403 ± 0.052	2.909ProGlu: 2.909 ± 0.057	1.896ProPhe: 1.896 ± 0.05	2.471ProGly: 2.471 ± 0.054	0.684ProHis: 0.684 ± 0.029	2.828ProIle: 2.828 ± 0.056	2.135ProLys: 2.135 ± 0.05	3.422ProLeu: 3.422 ± 0.058	0.758ProMet: 0.758 ± 0.033	2.029ProAsn: 2.029 ± 0.043	0.917ProPro: 0.917 ± 0.035	1.313ProGln: 1.313 ± 0.04	1.08ProArg: 1.08 ± 0.033	2.345ProSer: 2.345 ± 0.058	1.932ProThr: 1.932 ± 0.046	2.639ProVal: 2.639 ± 0.058	0.403ProTrp: 0.403 ± 0.023	1.489ProTyr: 1.489 ± 0.04	0.0ProXaa: 0.0 ± 0.0
Gln	2.547GlnAla: 2.547 ± 0.049	0.186GlnCys: 0.186 ± 0.014	1.745GlnAsp: 1.745 ± 0.044	2.562GlnGlu: 2.562 ± 0.057	1.674GlnPhe: 1.674 ± 0.043	2.134GlnGly: 2.134 ± 0.044	0.712GlnHis: 0.712 ± 0.025	2.794GlnIle: 2.794 ± 0.061	2.474GlnLys: 2.474 ± 0.051	3.791GlnLeu: 3.791 ± 0.069	0.799GlnMet: 0.799 ± 0.026	2.049GlnAsn: 2.049 ± 0.051	1.24GlnPro: 1.24 ± 0.035	1.743GlnGln: 1.743 ± 0.051	1.538GlnArg: 1.538 ± 0.044	2.287GlnSer: 2.287 ± 0.05	1.917GlnThr: 1.917 ± 0.047	2.292GlnVal: 2.292 ± 0.051	0.397GlnTrp: 0.397 ± 0.021	1.4GlnTyr: 1.4 ± 0.04	0.0GlnXaa: 0.0 ± 0.0
Arg	2.372ArgAla: 2.372 ± 0.05	0.189ArgCys: 0.189 ± 0.014	1.983ArgAsp: 1.983 ± 0.05	2.484ArgGlu: 2.484 ± 0.059	2.119ArgPhe: 2.119 ± 0.048	2.218ArgGly: 2.218 ± 0.055	0.572ArgHis: 0.572 ± 0.024	3.48ArgIle: 3.48 ± 0.063	3.005ArgLys: 3.005 ± 0.057	3.865ArgLeu: 3.865 ± 0.067	1.048ArgMet: 1.048 ± 0.032	2.373ArgAsn: 2.373 ± 0.049	1.332ArgPro: 1.332 ± 0.042	1.254ArgGln: 1.254 ± 0.038	1.506ArgArg: 1.506 ± 0.043	2.472ArgSer: 2.472 ± 0.052	2.009ArgThr: 2.009 ± 0.045	2.482ArgVal: 2.482 ± 0.054	0.447ArgTrp: 0.447 ± 0.021	1.736ArgTyr: 1.736 ± 0.054	0.0ArgXaa: 0.0 ± 0.0
Ser	4.461SerAla: 4.461 ± 0.072	0.561SerCys: 0.561 ± 0.024	3.36SerAsp: 3.36 ± 0.054	3.913SerGlu: 3.913 ± 0.073	3.995SerPhe: 3.995 ± 0.074	4.895SerGly: 4.895 ± 0.082	1.174SerHis: 1.174 ± 0.035	5.885SerIle: 5.885 ± 0.093	4.248SerLys: 4.248 ± 0.07	6.75SerLeu: 6.75 ± 0.093	1.481SerMet: 1.481 ± 0.04	3.643SerAsn: 3.643 ± 0.065	2.373SerPro: 2.373 ± 0.048	2.27SerGln: 2.27 ± 0.047	2.555SerArg: 2.555 ± 0.046	4.782SerSer: 4.782 ± 0.086	3.653SerThr: 3.653 ± 0.061	4.108SerVal: 4.108 ± 0.065	0.737SerTrp: 0.737 ± 0.03	2.886SerTyr: 2.886 ± 0.057	0.0SerXaa: 0.0 ± 0.0
Thr	3.734ThrAla: 3.734 ± 0.068	0.314ThrCys: 0.314 ± 0.019	3.028ThrAsp: 3.028 ± 0.061	3.112ThrGlu: 3.112 ± 0.067	2.682ThrPhe: 2.682 ± 0.056	4.076ThrGly: 4.076 ± 0.069	0.988ThrHis: 0.988 ± 0.036	4.376ThrIle: 4.376 ± 0.072	3.062ThrLys: 3.062 ± 0.063	5.259ThrLeu: 5.259 ± 0.076	1.025ThrMet: 1.025 ± 0.033	2.78ThrAsn: 2.78 ± 0.065	2.339ThrPro: 2.339 ± 0.045	1.818ThrGln: 1.818 ± 0.047	1.796ThrArg: 1.796 ± 0.046	3.471ThrSer: 3.471 ± 0.063	2.832ThrThr: 2.832 ± 0.065	3.522ThrVal: 3.522 ± 0.063	0.576ThrTrp: 0.576 ± 0.025	2.039ThrTyr: 2.039 ± 0.05	0.0ThrXaa: 0.0 ± 0.0
Val	4.157ValAla: 4.157 ± 0.081	0.528ValCys: 0.528 ± 0.024	3.461ValAsp: 3.461 ± 0.064	3.639ValGlu: 3.639 ± 0.061	3.252ValPhe: 3.252 ± 0.059	3.954ValGly: 3.954 ± 0.078	1.031ValHis: 1.031 ± 0.037	5.041ValIle: 5.041 ± 0.079	4.117ValLys: 4.117 ± 0.074	6.219ValLeu: 6.219 ± 0.085	1.297ValMet: 1.297 ± 0.041	3.433ValAsn: 3.433 ± 0.068	2.27ValPro: 2.27 ± 0.058	2.018ValGln: 2.018 ± 0.048	2.241ValArg: 2.241 ± 0.049	4.514ValSer: 4.514 ± 0.065	3.083ValThr: 3.083 ± 0.066	4.017ValVal: 4.017 ± 0.07	0.643ValTrp: 0.643 ± 0.025	2.292ValTyr: 2.292 ± 0.052	0.0ValXaa: 0.0 ± 0.0
Trp	0.654TrpAla: 0.654 ± 0.03	0.084TrpCys: 0.084 ± 0.009	0.588TrpAsp: 0.588 ± 0.028	0.651TrpGlu: 0.651 ± 0.026	0.568TrpPhe: 0.568 ± 0.027	0.741TrpGly: 0.741 ± 0.03	0.224TrpHis: 0.224 ± 0.016	0.822TrpIle: 0.822 ± 0.028	0.775TrpLys: 0.775 ± 0.035	1.159TrpLeu: 1.159 ± 0.039	0.337TrpMet: 0.337 ± 0.021	0.644TrpAsn: 0.644 ± 0.028	0.328TrpPro: 0.328 ± 0.016	0.427TrpGln: 0.427 ± 0.021	0.522TrpArg: 0.522 ± 0.024	0.578TrpSer: 0.578 ± 0.025	0.577TrpThr: 0.577 ± 0.025	0.657TrpVal: 0.657 ± 0.03	0.185TrpTrp: 0.185 ± 0.015	0.422TrpTyr: 0.422 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.395TyrAla: 2.395 ± 0.055	0.303TyrCys: 0.303 ± 0.019	2.115TyrAsp: 2.115 ± 0.045	2.215TyrGlu: 2.215 ± 0.055	2.229TyrPhe: 2.229 ± 0.054	2.747TyrGly: 2.747 ± 0.058	0.828TyrHis: 0.828 ± 0.033	2.769TyrIle: 2.769 ± 0.058	2.602TyrLys: 2.602 ± 0.06	3.811TyrLeu: 3.811 ± 0.068	0.77TyrMet: 0.77 ± 0.028	2.432TyrAsn: 2.432 ± 0.059	1.548TyrPro: 1.548 ± 0.041	1.646TyrGln: 1.646 ± 0.044	1.765TyrArg: 1.765 ± 0.042	2.817TyrSer: 2.817 ± 0.06	2.13TyrThr: 2.13 ± 0.054	1.971TyrVal: 1.971 ± 0.049	0.452TyrTrp: 0.452 ± 0.026	1.72TyrTyr: 1.72 ± 0.049	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2712 proteins (940648 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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