Amino acid dipepetide frequency for Bactrocera dorsalis (Oriental fruit fly) (Dacus dorsalis)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.585AlaAla: 8.585 ± 0.082	1.093AlaCys: 1.093 ± 0.014	3.588AlaAsp: 3.588 ± 0.024	4.549AlaGlu: 4.549 ± 0.037	2.221AlaPhe: 2.221 ± 0.019	4.125AlaGly: 4.125 ± 0.028	1.706AlaHis: 1.706 ± 0.016	3.774AlaIle: 3.774 ± 0.025	4.016AlaLys: 4.016 ± 0.028	6.219AlaLeu: 6.219 ± 0.038	1.617AlaMet: 1.617 ± 0.016	3.827AlaAsn: 3.827 ± 0.024	3.621AlaPro: 3.621 ± 0.034	3.191AlaGln: 3.191 ± 0.026	3.041AlaArg: 3.041 ± 0.025	5.654AlaSer: 5.654 ± 0.042	5.302AlaThr: 5.302 ± 0.041	4.485AlaVal: 4.485 ± 0.029	0.522AlaTrp: 0.522 ± 0.01	1.828AlaTyr: 1.828 ± 0.016	0.003AlaXaa: 0.003 ± 0.001
Cys	1.191CysAla: 1.191 ± 0.016	0.464CysCys: 0.464 ± 0.012	1.099CysAsp: 1.099 ± 0.018	1.137CysGlu: 1.137 ± 0.017	0.698CysPhe: 0.698 ± 0.011	1.254CysGly: 1.254 ± 0.018	0.444CysHis: 0.444 ± 0.009	1.058CysIle: 1.058 ± 0.015	1.028CysLys: 1.028 ± 0.015	1.588CysLeu: 1.588 ± 0.019	0.39CysMet: 0.39 ± 0.007	0.97CysAsn: 0.97 ± 0.016	0.842CysPro: 0.842 ± 0.016	0.683CysGln: 0.683 ± 0.012	0.917CysArg: 0.917 ± 0.015	1.448CysSer: 1.448 ± 0.018	0.979CysThr: 0.979 ± 0.013	1.132CysVal: 1.132 ± 0.015	0.189CysTrp: 0.189 ± 0.005	0.549CysTyr: 0.549 ± 0.011	0.001CysXaa: 0.001 ± 0.0
Asp	3.489AspAla: 3.489 ± 0.025	0.943AspCys: 0.943 ± 0.014	4.113AspAsp: 4.113 ± 0.048	4.374AspGlu: 4.374 ± 0.034	2.182AspPhe: 2.182 ± 0.017	3.018AspGly: 3.018 ± 0.027	0.994AspHis: 0.994 ± 0.012	3.317AspIle: 3.317 ± 0.025	2.888AspLys: 2.888 ± 0.022	4.571AspLeu: 4.571 ± 0.031	1.256AspMet: 1.256 ± 0.012	2.731AspAsn: 2.731 ± 0.022	2.095AspPro: 2.095 ± 0.018	1.545AspGln: 1.545 ± 0.015	2.232AspArg: 2.232 ± 0.021	3.965AspSer: 3.965 ± 0.031	2.754AspThr: 2.754 ± 0.021	3.386AspVal: 3.386 ± 0.023	0.561AspTrp: 0.561 ± 0.009	1.805AspTyr: 1.805 ± 0.017	0.001AspXaa: 0.001 ± 0.0
Glu	4.219GluAla: 4.219 ± 0.038	1.156GluCys: 1.156 ± 0.017	3.827GluAsp: 3.827 ± 0.03	5.681GluGlu: 5.681 ± 0.061	2.159GluPhe: 2.159 ± 0.018	2.604GluGly: 2.604 ± 0.022	1.653GluHis: 1.653 ± 0.015	3.793GluIle: 3.793 ± 0.028	4.633GluLys: 4.633 ± 0.042	5.96GluLeu: 5.96 ± 0.041	1.59GluMet: 1.59 ± 0.017	3.715GluAsn: 3.715 ± 0.028	2.402GluPro: 2.402 ± 0.027	3.15GluGln: 3.15 ± 0.028	3.949GluArg: 3.949 ± 0.032	4.332GluSer: 4.332 ± 0.032	3.52GluThr: 3.52 ± 0.027	3.546GluVal: 3.546 ± 0.028	0.573GluTrp: 0.573 ± 0.011	1.903GluTyr: 1.903 ± 0.017	0.002GluXaa: 0.002 ± 0.0
Phe	2.266PheAla: 2.266 ± 0.019	0.746PheCys: 0.746 ± 0.01	2.033PheAsp: 2.033 ± 0.017	2.204PheGlu: 2.204 ± 0.019	1.445PhePhe: 1.445 ± 0.015	2.371PheGly: 2.371 ± 0.024	0.885PheHis: 0.885 ± 0.01	2.082PheIle: 2.082 ± 0.02	2.015PheLys: 2.015 ± 0.02	3.276PheLeu: 3.276 ± 0.03	0.851PheMet: 0.851 ± 0.013	1.868PheAsn: 1.868 ± 0.017	1.474PhePro: 1.474 ± 0.015	1.415PheGln: 1.415 ± 0.014	1.754PheArg: 1.754 ± 0.017	2.63PheSer: 2.63 ± 0.021	1.995PheThr: 1.995 ± 0.018	2.335PheVal: 2.335 ± 0.019	0.394PheTrp: 0.394 ± 0.009	1.29PheTyr: 1.29 ± 0.016	0.002PheXaa: 0.002 ± 0.001
Gly	4.115GlyAla: 4.115 ± 0.033	0.924GlyCys: 0.924 ± 0.014	2.844GlyAsp: 2.844 ± 0.023	2.951GlyGlu: 2.951 ± 0.024	2.033GlyPhe: 2.033 ± 0.022	5.939GlyGly: 5.939 ± 0.077	1.358GlyHis: 1.358 ± 0.018	3.05GlyIle: 3.05 ± 0.025	3.044GlyLys: 3.044 ± 0.023	4.189GlyLeu: 4.189 ± 0.031	1.244GlyMet: 1.244 ± 0.017	3.249GlyAsn: 3.249 ± 0.034	2.267GlyPro: 2.267 ± 0.039	1.935GlyGln: 1.935 ± 0.018	2.702GlyArg: 2.702 ± 0.024	5.056GlySer: 5.056 ± 0.041	3.099GlyThr: 3.099 ± 0.023	3.565GlyVal: 3.565 ± 0.026	0.538GlyTrp: 0.538 ± 0.01	1.865GlyTyr: 1.865 ± 0.023	0.002GlyXaa: 0.002 ± 0.0
His	1.58HisAla: 1.58 ± 0.017	0.535HisCys: 0.535 ± 0.009	1.089HisAsp: 1.089 ± 0.013	1.38HisGlu: 1.38 ± 0.015	1.048HisPhe: 1.048 ± 0.012	1.314HisGly: 1.314 ± 0.015	1.322HisHis: 1.322 ± 0.029	1.505HisIle: 1.505 ± 0.015	1.386HisLys: 1.386 ± 0.016	2.405HisLeu: 2.405 ± 0.021	0.692HisMet: 0.692 ± 0.013	1.415HisAsn: 1.415 ± 0.016	1.229HisPro: 1.229 ± 0.015	1.48HisGln: 1.48 ± 0.023	1.303HisArg: 1.303 ± 0.016	2.15HisSer: 2.15 ± 0.024	1.545HisThr: 1.545 ± 0.017	1.346HisVal: 1.346 ± 0.015	0.266HisTrp: 0.266 ± 0.006	0.853HisTyr: 0.853 ± 0.01	0.001HisXaa: 0.001 ± 0.0
Ile	3.853IleAla: 3.853 ± 0.024	1.262IleCys: 1.262 ± 0.016	3.087IleAsp: 3.087 ± 0.024	3.647IleGlu: 3.647 ± 0.028	2.276IlePhe: 2.276 ± 0.021	2.928IleGly: 2.928 ± 0.026	1.213IleHis: 1.213 ± 0.014	3.166IleIle: 3.166 ± 0.025	3.344IleLys: 3.344 ± 0.025	4.716IleLeu: 4.716 ± 0.029	1.186IleMet: 1.186 ± 0.014	2.978IleAsn: 2.978 ± 0.021	2.635IlePro: 2.635 ± 0.02	2.165IleGln: 2.165 ± 0.021	2.51IleArg: 2.51 ± 0.019	4.584IleSer: 4.584 ± 0.025	3.416IleThr: 3.416 ± 0.023	3.349IleVal: 3.349 ± 0.024	0.533IleTrp: 0.533 ± 0.01	1.823IleTyr: 1.823 ± 0.022	0.001IleXaa: 0.001 ± 0.0
Lys	3.633LysAla: 3.633 ± 0.028	1.178LysCys: 1.178 ± 0.016	3.073LysAsp: 3.073 ± 0.026	4.205LysGlu: 4.205 ± 0.035	2.087LysPhe: 2.087 ± 0.02	2.387LysGly: 2.387 ± 0.024	1.55LysHis: 1.55 ± 0.015	3.406LysIle: 3.406 ± 0.026	4.589LysLys: 4.589 ± 0.04	5.562LysLeu: 5.562 ± 0.035	1.506LysMet: 1.506 ± 0.015	3.116LysAsn: 3.116 ± 0.024	2.872LysPro: 2.872 ± 0.029	2.92LysGln: 2.92 ± 0.024	3.831LysArg: 3.831 ± 0.031	4.792LysSer: 4.792 ± 0.036	3.552LysThr: 3.552 ± 0.025	3.25LysVal: 3.25 ± 0.027	0.602LysTrp: 0.602 ± 0.009	2.004LysTyr: 2.004 ± 0.02	0.001LysXaa: 0.001 ± 0.0
Leu	5.967LeuAla: 5.967 ± 0.032	1.653LeuCys: 1.653 ± 0.015	4.422LeuAsp: 4.422 ± 0.029	5.893LeuGlu: 5.893 ± 0.044	2.99LeuPhe: 2.99 ± 0.024	4.208LeuGly: 4.208 ± 0.035	2.407LeuHis: 2.407 ± 0.024	4.433LeuIle: 4.433 ± 0.028	5.707LeuLys: 5.707 ± 0.038	8.558LeuLeu: 8.558 ± 0.051	1.937LeuMet: 1.937 ± 0.019	4.788LeuAsn: 4.788 ± 0.033	4.739LeuPro: 4.739 ± 0.028	5.029LeuGln: 5.029 ± 0.03	5.046LeuArg: 5.046 ± 0.033	6.847LeuSer: 6.847 ± 0.034	5.063LeuThr: 5.063 ± 0.029	4.602LeuVal: 4.602 ± 0.032	0.801LeuTrp: 0.801 ± 0.012	2.503LeuTyr: 2.503 ± 0.021	0.002LeuXaa: 0.002 ± 0.001
Met	1.67MetAla: 1.67 ± 0.016	0.391MetCys: 0.391 ± 0.008	1.282MetAsp: 1.282 ± 0.014	1.536MetGlu: 1.536 ± 0.016	0.774MetPhe: 0.774 ± 0.01	1.245MetGly: 1.245 ± 0.017	0.626MetHis: 0.626 ± 0.009	0.973MetIle: 0.973 ± 0.011	1.363MetLys: 1.363 ± 0.013	2.088MetLeu: 2.088 ± 0.019	0.568MetMet: 0.568 ± 0.01	1.118MetAsn: 1.118 ± 0.013	1.31MetPro: 1.31 ± 0.016	1.298MetGln: 1.298 ± 0.014	1.362MetArg: 1.362 ± 0.012	1.928MetSer: 1.928 ± 0.018	1.208MetThr: 1.208 ± 0.013	1.176MetVal: 1.176 ± 0.013	0.22MetTrp: 0.22 ± 0.005	0.655MetTyr: 0.655 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	4.267AsnAla: 4.267 ± 0.028	1.058AsnCys: 1.058 ± 0.014	2.826AsnAsp: 2.826 ± 0.025	3.562AsnGlu: 3.562 ± 0.025	2.022AsnPhe: 2.022 ± 0.02	3.59AsnGly: 3.59 ± 0.037	1.167AsnHis: 1.167 ± 0.014	3.38AsnIle: 3.38 ± 0.024	3.176AsnLys: 3.176 ± 0.025	4.5AsnLeu: 4.5 ± 0.028	1.319AsnMet: 1.319 ± 0.017	4.411AsnAsn: 4.411 ± 0.059	2.175AsnPro: 2.175 ± 0.021	2.008AsnGln: 2.008 ± 0.018	2.358AsnArg: 2.358 ± 0.018	5.166AsnSer: 5.166 ± 0.042	3.599AsnThr: 3.599 ± 0.028	3.365AsnVal: 3.365 ± 0.021	0.49AsnTrp: 0.49 ± 0.008	1.722AsnTyr: 1.722 ± 0.018	0.002AsnXaa: 0.002 ± 0.0
Pro	3.679ProAla: 3.679 ± 0.034	0.643ProCys: 0.643 ± 0.013	2.187ProAsp: 2.187 ± 0.019	2.908ProGlu: 2.908 ± 0.026	1.562ProPhe: 1.562 ± 0.016	2.47ProGly: 2.47 ± 0.039	1.337ProHis: 1.337 ± 0.018	2.651ProIle: 2.651 ± 0.021	2.857ProLys: 2.857 ± 0.022	4.122ProLeu: 4.122 ± 0.025	1.038ProMet: 1.038 ± 0.013	2.619ProAsn: 2.619 ± 0.022	4.499ProPro: 4.499 ± 0.061	2.674ProGln: 2.674 ± 0.032	2.146ProArg: 2.146 ± 0.019	4.065ProSer: 4.065 ± 0.031	3.933ProThr: 3.933 ± 0.036	2.904ProVal: 2.904 ± 0.026	0.407ProTrp: 0.407 ± 0.008	1.446ProTyr: 1.446 ± 0.018	0.003ProXaa: 0.003 ± 0.001
Gln	2.898GlnAla: 2.898 ± 0.022	0.763GlnCys: 0.763 ± 0.014	1.651GlnAsp: 1.651 ± 0.015	2.58GlnGlu: 2.58 ± 0.026	1.472GlnPhe: 1.472 ± 0.014	1.674GlnGly: 1.674 ± 0.02	1.918GlnHis: 1.918 ± 0.027	2.42GlnIle: 2.42 ± 0.021	2.815GlnLys: 2.815 ± 0.025	4.68GlnLeu: 4.68 ± 0.029	1.228GlnMet: 1.228 ± 0.015	2.471GlnAsn: 2.471 ± 0.024	2.529GlnPro: 2.529 ± 0.029	7.188GlnGln: 7.188 ± 0.138	2.987GlnArg: 2.987 ± 0.023	3.383GlnSer: 3.383 ± 0.027	2.79GlnThr: 2.79 ± 0.022	2.178GlnVal: 2.178 ± 0.019	0.405GlnTrp: 0.405 ± 0.008	1.367GlnTyr: 1.367 ± 0.017	0.001GlnXaa: 0.001 ± 0.0
Arg	3.07ArgAla: 3.07 ± 0.02	0.949ArgCys: 0.949 ± 0.015	2.61ArgAsp: 2.61 ± 0.022	3.374ArgGlu: 3.374 ± 0.032	1.877ArgPhe: 1.877 ± 0.019	2.513ArgGly: 2.513 ± 0.025	1.421ArgHis: 1.421 ± 0.017	2.828ArgIle: 2.828 ± 0.021	3.712ArgLys: 3.712 ± 0.028	4.533ArgLeu: 4.533 ± 0.028	1.107ArgMet: 1.107 ± 0.012	2.919ArgAsn: 2.919 ± 0.024	2.347ArgPro: 2.347 ± 0.024	2.5ArgGln: 2.5 ± 0.018	3.933ArgArg: 3.933 ± 0.041	4.112ArgSer: 4.112 ± 0.037	2.772ArgThr: 2.772 ± 0.022	2.605ArgVal: 2.605 ± 0.019	0.477ArgTrp: 0.477 ± 0.01	1.655ArgTyr: 1.655 ± 0.015	0.002ArgXaa: 0.002 ± 0.001
Ser	6.298SerAla: 6.298 ± 0.043	1.287SerCys: 1.287 ± 0.018	4.097SerAsp: 4.097 ± 0.027	4.454SerGlu: 4.454 ± 0.031	2.649SerPhe: 2.649 ± 0.019	5.365SerGly: 5.365 ± 0.047	1.879SerHis: 1.879 ± 0.022	4.172SerIle: 4.172 ± 0.023	4.448SerLys: 4.448 ± 0.033	6.573SerLeu: 6.573 ± 0.036	1.738SerMet: 1.738 ± 0.015	5.171SerAsn: 5.171 ± 0.044	4.398SerPro: 4.398 ± 0.045	3.243SerGln: 3.243 ± 0.028	3.627SerArg: 3.627 ± 0.036	9.513SerSer: 9.513 ± 0.093	6.163SerThr: 6.163 ± 0.048	4.561SerVal: 4.561 ± 0.029	0.643SerTrp: 0.643 ± 0.009	2.191SerTyr: 2.191 ± 0.02	0.002SerXaa: 0.002 ± 0.001
Thr	5.244ThrAla: 5.244 ± 0.037	0.993ThrCys: 0.993 ± 0.016	2.958ThrAsp: 2.958 ± 0.021	3.618ThrGlu: 3.618 ± 0.031	2.036ThrPhe: 2.036 ± 0.019	3.237ThrGly: 3.237 ± 0.028	1.527ThrHis: 1.527 ± 0.015	3.354ThrIle: 3.354 ± 0.021	3.444ThrLys: 3.444 ± 0.023	5.287ThrLeu: 5.287 ± 0.028	1.285ThrMet: 1.285 ± 0.016	3.568ThrAsn: 3.568 ± 0.028	4.04ThrPro: 4.04 ± 0.034	2.762ThrGln: 2.762 ± 0.024	2.563ThrArg: 2.563 ± 0.021	5.663ThrSer: 5.663 ± 0.044	6.203ThrThr: 6.203 ± 0.083	3.714ThrVal: 3.714 ± 0.025	0.472ThrTrp: 0.472 ± 0.009	1.663ThrTyr: 1.663 ± 0.017	0.003ThrXaa: 0.003 ± 0.001
Val	4.451ValAla: 4.451 ± 0.029	1.168ValCys: 1.168 ± 0.015	3.208ValAsp: 3.208 ± 0.024	3.835ValGlu: 3.835 ± 0.031	2.087ValPhe: 2.087 ± 0.018	3.371ValGly: 3.371 ± 0.026	1.409ValHis: 1.409 ± 0.017	3.137ValIle: 3.137 ± 0.025	3.333ValLys: 3.333 ± 0.023	5.087ValLeu: 5.087 ± 0.034	1.246ValMet: 1.246 ± 0.013	3.008ValAsn: 3.008 ± 0.022	3.002ValPro: 3.002 ± 0.021	2.487ValGln: 2.487 ± 0.02	2.824ValArg: 2.824 ± 0.021	4.35ValSer: 4.35 ± 0.026	3.509ValThr: 3.509 ± 0.025	3.775ValVal: 3.775 ± 0.032	0.536ValTrp: 0.536 ± 0.008	1.669ValTyr: 1.669 ± 0.017	0.002ValXaa: 0.002 ± 0.0
Trp	0.509TrpAla: 0.509 ± 0.009	0.195TrpCys: 0.195 ± 0.006	0.475TrpAsp: 0.475 ± 0.008	0.503TrpGlu: 0.503 ± 0.008	0.379TrpPhe: 0.379 ± 0.008	0.47TrpGly: 0.47 ± 0.009	0.254TrpHis: 0.254 ± 0.006	0.516TrpIle: 0.516 ± 0.01	0.56TrpLys: 0.56 ± 0.01	1.001TrpLeu: 1.001 ± 0.013	0.241TrpMet: 0.241 ± 0.006	0.494TrpAsn: 0.494 ± 0.008	0.358TrpPro: 0.358 ± 0.008	0.448TrpGln: 0.448 ± 0.009	0.592TrpArg: 0.592 ± 0.009	0.666TrpSer: 0.666 ± 0.01	0.504TrpThr: 0.504 ± 0.009	0.48TrpVal: 0.48 ± 0.008	0.142TrpTrp: 0.142 ± 0.004	0.311TrpTyr: 0.311 ± 0.006	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.98TyrAla: 1.98 ± 0.02	0.659TyrCys: 0.659 ± 0.011	1.752TyrAsp: 1.752 ± 0.018	1.973TyrGlu: 1.973 ± 0.019	1.33TyrPhe: 1.33 ± 0.016	1.886TyrGly: 1.886 ± 0.023	0.771TyrHis: 0.771 ± 0.011	1.656TyrIle: 1.656 ± 0.016	1.753TyrLys: 1.753 ± 0.015	2.679TyrLeu: 2.679 ± 0.021	0.755TyrMet: 0.755 ± 0.011	1.724TyrAsn: 1.724 ± 0.019	1.315TyrPro: 1.315 ± 0.016	1.274TyrGln: 1.274 ± 0.014	1.638TyrArg: 1.638 ± 0.015	2.167TyrSer: 2.167 ± 0.02	1.728TyrThr: 1.728 ± 0.018	1.738TyrVal: 1.738 ± 0.018	0.328TyrTrp: 0.328 ± 0.008	1.185TyrTyr: 1.185 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.002XaaAla: 0.002 ± 0.0	0.001XaaCys: 0.001 ± 0.0	0.001XaaAsp: 0.001 ± 0.0	0.002XaaGlu: 0.002 ± 0.0	0.002XaaPhe: 0.002 ± 0.0	0.002XaaGly: 0.002 ± 0.001	0.001XaaHis: 0.001 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.004XaaLys: 0.004 ± 0.001	0.002XaaLeu: 0.002 ± 0.001	0.0XaaMet: 0.0 ± 0.0	0.002XaaAsn: 0.002 ± 0.001	0.002XaaPro: 0.002 ± 0.0	0.002XaaGln: 0.002 ± 0.001	0.001XaaArg: 0.001 ± 0.0	0.002XaaSer: 0.002 ± 0.001	0.002XaaThr: 0.002 ± 0.001	0.002XaaVal: 0.002 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.002XaaTyr: 0.002 ± 0.0	0.012XaaXaa: 0.012 ± 0.006

Statistics based on 13409 proteins (8119786 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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