Amino acid dipepetide frequency for Stackebrandtia albiflava

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
21.588AlaAla: 21.588 ± 0.191
1.009AlaCys: 1.009 ± 0.023
8.981AlaAsp: 8.981 ± 0.084
9.135AlaGlu: 9.135 ± 0.094
3.188AlaPhe: 3.188 ± 0.046
12.603AlaGly: 12.603 ± 0.111
2.602AlaHis: 2.602 ± 0.04
4.054AlaIle: 4.054 ± 0.049
2.222AlaLys: 2.222 ± 0.043
12.765AlaLeu: 12.765 ± 0.118
2.883AlaMet: 2.883 ± 0.044
1.875AlaAsn: 1.875 ± 0.036
6.14AlaPro: 6.14 ± 0.085
3.041AlaGln: 3.041 ± 0.053
9.566AlaArg: 9.566 ± 0.1
5.28AlaSer: 5.28 ± 0.056
7.705AlaThr: 7.705 ± 0.069
12.986AlaVal: 12.986 ± 0.11
1.861AlaTrp: 1.861 ± 0.035
2.31AlaTyr: 2.31 ± 0.037
0.0AlaXaa: 0.0 ± 0.0
Cys
0.94CysAla: 0.94 ± 0.026
0.126CysCys: 0.126 ± 0.01
0.655CysAsp: 0.655 ± 0.023
0.446CysGlu: 0.446 ± 0.016
0.219CysPhe: 0.219 ± 0.013
1.054CysGly: 1.054 ± 0.028
0.233CysHis: 0.233 ± 0.013
0.164CysIle: 0.164 ± 0.01
0.075CysLys: 0.075 ± 0.008
0.756CysLeu: 0.756 ± 0.021
0.127CysMet: 0.127 ± 0.011
0.136CysAsn: 0.136 ± 0.008
0.482CysPro: 0.482 ± 0.021
0.15CysGln: 0.15 ± 0.009
0.733CysArg: 0.733 ± 0.024
0.364CysSer: 0.364 ± 0.017
0.405CysThr: 0.405 ± 0.016
0.71CysVal: 0.71 ± 0.02
0.131CysTrp: 0.131 ± 0.009
0.162CysTyr: 0.162 ± 0.01
0.0CysXaa: 0.0 ± 0.0
Asp
8.052AspAla: 8.052 ± 0.079
0.529AspCys: 0.529 ± 0.02
4.645AspAsp: 4.645 ± 0.068
3.971AspGlu: 3.971 ± 0.055
1.857AspPhe: 1.857 ± 0.033
6.784AspGly: 6.784 ± 0.08
1.59AspHis: 1.59 ± 0.033
2.062AspIle: 2.062 ± 0.037
0.895AspLys: 0.895 ± 0.027
6.346AspLeu: 6.346 ± 0.078
1.144AspMet: 1.144 ± 0.03
1.016AspAsn: 1.016 ± 0.028
4.922AspPro: 4.922 ± 0.061
1.378AspGln: 1.378 ± 0.033
5.8AspArg: 5.8 ± 0.071
2.955AspSer: 2.955 ± 0.039
4.046AspThr: 4.046 ± 0.044
5.633AspVal: 5.633 ± 0.07
1.146AspTrp: 1.146 ± 0.028
1.332AspTyr: 1.332 ± 0.033
0.0AspXaa: 0.0 ± 0.0
Glu
7.117GluAla: 7.117 ± 0.074
0.464GluCys: 0.464 ± 0.018
2.839GluAsp: 2.839 ± 0.042
3.053GluGlu: 3.053 ± 0.051
1.842GluPhe: 1.842 ± 0.032
3.723GluGly: 3.723 ± 0.055
1.261GluHis: 1.261 ± 0.031
2.311GluIle: 2.311 ± 0.041
0.99GluLys: 0.99 ± 0.029
6.556GluLeu: 6.556 ± 0.076
0.999GluMet: 0.999 ± 0.025
0.999GluAsn: 0.999 ± 0.027
3.8GluPro: 3.8 ± 0.055
1.772GluGln: 1.772 ± 0.04
5.039GluArg: 5.039 ± 0.059
3.232GluSer: 3.232 ± 0.047
3.402GluThr: 3.402 ± 0.054
4.86GluVal: 4.86 ± 0.053
1.034GluTrp: 1.034 ± 0.026
1.431GluTyr: 1.431 ± 0.033
0.0GluXaa: 0.0 ± 0.0
Phe
3.854PheAla: 3.854 ± 0.05
0.257PheCys: 0.257 ± 0.013
2.363PheAsp: 2.363 ± 0.046
1.347PheGlu: 1.347 ± 0.032
0.786PhePhe: 0.786 ± 0.026
3.244PheGly: 3.244 ± 0.045
0.743PheHis: 0.743 ± 0.023
0.886PheIle: 0.886 ± 0.025
0.406PheLys: 0.406 ± 0.015
2.457PheLeu: 2.457 ± 0.044
0.424PheMet: 0.424 ± 0.017
0.552PheAsn: 0.552 ± 0.019
1.339PhePro: 1.339 ± 0.031
0.673PheGln: 0.673 ± 0.019
1.919PheArg: 1.919 ± 0.033
1.44PheSer: 1.44 ± 0.03
2.312PheThr: 2.312 ± 0.038
2.262PheVal: 2.262 ± 0.042
0.419PheTrp: 0.419 ± 0.016
0.577PheTyr: 0.577 ± 0.018
0.0PheXaa: 0.0 ± 0.0
Gly
9.464GlyAla: 9.464 ± 0.101
0.871GlyCys: 0.871 ± 0.027
6.464GlyAsp: 6.464 ± 0.07
5.427GlyGlu: 5.427 ± 0.053
3.277GlyPhe: 3.277 ± 0.047
8.484GlyGly: 8.484 ± 0.096
2.371GlyHis: 2.371 ± 0.041
3.408GlyIle: 3.408 ± 0.049
1.723GlyLys: 1.723 ± 0.037
9.204GlyLeu: 9.204 ± 0.079
2.332GlyMet: 2.332 ± 0.04
1.816GlyAsn: 1.816 ± 0.04
4.521GlyPro: 4.521 ± 0.061
2.181GlyGln: 2.181 ± 0.043
7.617GlyArg: 7.617 ± 0.092
4.297GlySer: 4.297 ± 0.059
5.592GlyThr: 5.592 ± 0.069
8.218GlyVal: 8.218 ± 0.086
1.802GlyTrp: 1.802 ± 0.031
2.479GlyTyr: 2.479 ± 0.048
0.0GlyXaa: 0.0 ± 0.0
His
2.547HisAla: 2.547 ± 0.046
0.209HisCys: 0.209 ± 0.01
1.564HisAsp: 1.564 ± 0.029
1.117HisGlu: 1.117 ± 0.023
0.62HisPhe: 0.62 ± 0.023
2.338HisGly: 2.338 ± 0.044
0.81HisHis: 0.81 ± 0.029
0.762HisIle: 0.762 ± 0.021
0.248HisLys: 0.248 ± 0.013
2.364HisLeu: 2.364 ± 0.04
0.398HisMet: 0.398 ± 0.014
0.375HisAsn: 0.375 ± 0.017
1.693HisPro: 1.693 ± 0.032
0.506HisGln: 0.506 ± 0.017
2.621HisArg: 2.621 ± 0.041
0.979HisSer: 0.979 ± 0.023
1.423HisThr: 1.423 ± 0.032
1.815HisVal: 1.815 ± 0.037
0.386HisTrp: 0.386 ± 0.018
0.462HisTyr: 0.462 ± 0.019
0.0HisXaa: 0.0 ± 0.0
Ile
5.349IleAla: 5.349 ± 0.061
0.292IleCys: 0.292 ± 0.012
2.702IleAsp: 2.702 ± 0.046
1.998IleGlu: 1.998 ± 0.038
0.654IlePhe: 0.654 ± 0.023
3.839IleGly: 3.839 ± 0.049
0.7IleHis: 0.7 ± 0.02
0.974IleIle: 0.974 ± 0.033
0.558IleLys: 0.558 ± 0.019
2.806IleLeu: 2.806 ± 0.047
0.549IleMet: 0.549 ± 0.019
0.643IleAsn: 0.643 ± 0.021
2.108IlePro: 2.108 ± 0.036
0.694IleGln: 0.694 ± 0.017
2.682IleArg: 2.682 ± 0.045
1.629IleSer: 1.629 ± 0.035
2.415IleThr: 2.415 ± 0.037
3.1IleVal: 3.1 ± 0.053
0.383IleTrp: 0.383 ± 0.015
0.484IleTyr: 0.484 ± 0.019
0.0IleXaa: 0.0 ± 0.0
Lys
2.151LysAla: 2.151 ± 0.044
0.098LysCys: 0.098 ± 0.009
0.83LysAsp: 0.83 ± 0.029
0.813LysGlu: 0.813 ± 0.03
0.369LysPhe: 0.369 ± 0.015
1.173LysGly: 1.173 ± 0.032
0.314LysHis: 0.314 ± 0.015
0.678LysIle: 0.678 ± 0.022
0.463LysLys: 0.463 ± 0.023
1.517LysLeu: 1.517 ± 0.035
0.291LysMet: 0.291 ± 0.015
0.351LysAsn: 0.351 ± 0.017
1.076LysPro: 1.076 ± 0.029
0.472LysGln: 0.472 ± 0.018
1.286LysArg: 1.286 ± 0.035
0.977LysSer: 0.977 ± 0.028
1.083LysThr: 1.083 ± 0.027
1.476LysVal: 1.476 ± 0.035
0.238LysTrp: 0.238 ± 0.012
0.341LysTyr: 0.341 ± 0.014
0.0LysXaa: 0.0 ± 0.0
Leu
14.938LeuAla: 14.938 ± 0.138
0.793LeuCys: 0.793 ± 0.024
6.459LeuAsp: 6.459 ± 0.078
4.333LeuGlu: 4.333 ± 0.057
2.648LeuPhe: 2.648 ± 0.051
8.216LeuGly: 8.216 ± 0.09
2.194LeuHis: 2.194 ± 0.042
3.552LeuIle: 3.552 ± 0.053
1.472LeuLys: 1.472 ± 0.037
10.701LeuLeu: 10.701 ± 0.107
1.58LeuMet: 1.58 ± 0.034
1.613LeuAsn: 1.613 ± 0.028
6.097LeuPro: 6.097 ± 0.067
1.799LeuGln: 1.799 ± 0.038
8.702LeuArg: 8.702 ± 0.093
5.618LeuSer: 5.618 ± 0.059
7.089LeuThr: 7.089 ± 0.071
8.678LeuVal: 8.678 ± 0.08
1.51LeuTrp: 1.51 ± 0.03
1.803LeuTyr: 1.803 ± 0.034
0.0LeuXaa: 0.0 ± 0.0
Met
2.461MetAla: 2.461 ± 0.04
0.146MetCys: 0.146 ± 0.009
0.963MetAsp: 0.963 ± 0.026
0.83MetGlu: 0.83 ± 0.025
0.568MetPhe: 0.568 ± 0.016
1.331MetGly: 1.331 ± 0.032
0.326MetHis: 0.326 ± 0.013
0.75MetIle: 0.75 ± 0.024
0.372MetLys: 0.372 ± 0.015
2.002MetLeu: 2.002 ± 0.032
0.36MetMet: 0.36 ± 0.016
0.482MetAsn: 0.482 ± 0.016
1.296MetPro: 1.296 ± 0.028
0.409MetGln: 0.409 ± 0.016
1.71MetArg: 1.71 ± 0.033
1.512MetSer: 1.512 ± 0.032
1.954MetThr: 1.954 ± 0.037
1.518MetVal: 1.518 ± 0.034
0.271MetTrp: 0.271 ± 0.012
0.394MetTyr: 0.394 ± 0.013
0.0MetXaa: 0.0 ± 0.0
Asn
1.993AsnAla: 1.993 ± 0.042
0.171AsnCys: 0.171 ± 0.01
0.994AsnAsp: 0.994 ± 0.026
0.791AsnGlu: 0.791 ± 0.022
0.42AsnPhe: 0.42 ± 0.018
1.732AsnGly: 1.732 ± 0.036
0.411AsnHis: 0.411 ± 0.016
0.61AsnIle: 0.61 ± 0.02
0.294AsnLys: 0.294 ± 0.017
1.828AsnLeu: 1.828 ± 0.038
0.278AsnMet: 0.278 ± 0.014
0.388AsnAsn: 0.388 ± 0.018
1.463AsnPro: 1.463 ± 0.031
0.459AsnGln: 0.459 ± 0.018
1.51AsnArg: 1.51 ± 0.033
0.791AsnSer: 0.791 ± 0.025
1.045AsnThr: 1.045 ± 0.029
1.351AsnVal: 1.351 ± 0.031
0.287AsnTrp: 0.287 ± 0.015
0.354AsnTyr: 0.354 ± 0.017
0.0AsnXaa: 0.0 ± 0.0
Pro
7.834ProAla: 7.834 ± 0.086
0.304ProCys: 0.304 ± 0.015
4.893ProAsp: 4.893 ± 0.058
4.55ProGlu: 4.55 ± 0.056
1.526ProPhe: 1.526 ± 0.031
6.749ProGly: 6.749 ± 0.098
1.432ProHis: 1.432 ± 0.034
1.567ProIle: 1.567 ± 0.031
0.927ProLys: 0.927 ± 0.025
4.666ProLeu: 4.666 ± 0.05
1.167ProMet: 1.167 ± 0.027
0.864ProAsn: 0.864 ± 0.026
4.245ProPro: 4.245 ± 0.097
1.606ProGln: 1.606 ± 0.035
3.93ProArg: 3.93 ± 0.057
2.902ProSer: 2.902 ± 0.051
3.254ProThr: 3.254 ± 0.051
6.012ProVal: 6.012 ± 0.075
0.875ProTrp: 0.875 ± 0.024
1.163ProTyr: 1.163 ± 0.027
0.0ProXaa: 0.0 ± 0.0
Gln
3.13GlnAla: 3.13 ± 0.053
0.161GlnCys: 0.161 ± 0.01
1.046GlnAsp: 1.046 ± 0.026
1.117GlnGlu: 1.117 ± 0.029
0.638GlnPhe: 0.638 ± 0.022
1.63GlnGly: 1.63 ± 0.031
0.529GlnHis: 0.529 ± 0.018
1.054GlnIle: 1.054 ± 0.028
0.346GlnLys: 0.346 ± 0.017
2.568GlnLeu: 2.568 ± 0.045
0.445GlnMet: 0.445 ± 0.017
0.446GlnAsn: 0.446 ± 0.018
1.493GlnPro: 1.493 ± 0.039
0.932GlnGln: 0.932 ± 0.032
2.239GlnArg: 2.239 ± 0.035
1.152GlnSer: 1.152 ± 0.026
1.269GlnThr: 1.269 ± 0.03
2.278GlnVal: 2.278 ± 0.043
0.467GlnTrp: 0.467 ± 0.018
0.535GlnTyr: 0.535 ± 0.022
0.0GlnXaa: 0.0 ± 0.0
Arg
8.644ArgAla: 8.644 ± 0.096
0.652ArgCys: 0.652 ± 0.022
5.276ArgAsp: 5.276 ± 0.069
4.554ArgGlu: 4.554 ± 0.056
2.982ArgPhe: 2.982 ± 0.056
5.484ArgGly: 5.484 ± 0.062
2.578ArgHis: 2.578 ± 0.045
3.715ArgIle: 3.715 ± 0.052
1.386ArgLys: 1.386 ± 0.035
10.084ArgLeu: 10.084 ± 0.119
2.029ArgMet: 2.029 ± 0.032
1.447ArgAsn: 1.447 ± 0.029
4.943ArgPro: 4.943 ± 0.062
2.244ArgGln: 2.244 ± 0.039
9.389ArgArg: 9.389 ± 0.113
3.882ArgSer: 3.882 ± 0.061
4.373ArgThr: 4.373 ± 0.048
6.161ArgVal: 6.161 ± 0.065
1.488ArgTrp: 1.488 ± 0.032
2.042ArgTyr: 2.042 ± 0.04
0.0ArgXaa: 0.0 ± 0.0
Ser
6.225SerAla: 6.225 ± 0.066
0.406SerCys: 0.406 ± 0.019
2.99SerAsp: 2.99 ± 0.046
2.586SerGlu: 2.586 ± 0.042
1.343SerPhe: 1.343 ± 0.028
5.749SerGly: 5.749 ± 0.065
1.192SerHis: 1.192 ± 0.024
1.631SerIle: 1.631 ± 0.037
0.769SerLys: 0.769 ± 0.024
4.604SerLeu: 4.604 ± 0.053
1.115SerMet: 1.115 ± 0.029
0.74SerAsn: 0.74 ± 0.023
3.404SerPro: 3.404 ± 0.052
1.261SerGln: 1.261 ± 0.031
4.006SerArg: 4.006 ± 0.05
2.331SerSer: 2.331 ± 0.039
2.869SerThr: 2.869 ± 0.037
4.204SerVal: 4.204 ± 0.049
0.772SerTrp: 0.772 ± 0.019
1.078SerTyr: 1.078 ± 0.028
0.0SerXaa: 0.0 ± 0.0
Thr
9.161ThrAla: 9.161 ± 0.09
0.417ThrCys: 0.417 ± 0.019
4.274ThrAsp: 4.274 ± 0.051
3.759ThrGlu: 3.759 ± 0.052
1.442ThrPhe: 1.442 ± 0.032
7.52ThrGly: 7.52 ± 0.087
1.148ThrHis: 1.148 ± 0.027
1.891ThrIle: 1.891 ± 0.036
0.837ThrLys: 0.837 ± 0.026
5.379ThrLeu: 5.379 ± 0.06
1.227ThrMet: 1.227 ± 0.028
0.866ThrAsn: 0.866 ± 0.027
4.262ThrPro: 4.262 ± 0.054
1.064ThrGln: 1.064 ± 0.025
4.206ThrArg: 4.206 ± 0.05
2.957ThrSer: 2.957 ± 0.043
4.19ThrThr: 4.19 ± 0.066
7.081ThrVal: 7.081 ± 0.081
0.924ThrTrp: 0.924 ± 0.026
1.088ThrTyr: 1.088 ± 0.031
0.0ThrXaa: 0.0 ± 0.0
Val
12.559ValAla: 12.559 ± 0.107
0.8ValCys: 0.8 ± 0.021
5.924ValAsp: 5.924 ± 0.071
5.058ValGlu: 5.058 ± 0.059
2.652ValPhe: 2.652 ± 0.049
6.795ValGly: 6.795 ± 0.076
1.872ValHis: 1.872 ± 0.036
3.284ValIle: 3.284 ± 0.05
1.507ValLys: 1.507 ± 0.04
8.999ValLeu: 8.999 ± 0.085
1.715ValMet: 1.715 ± 0.035
1.747ValAsn: 1.747 ± 0.036
5.121ValPro: 5.121 ± 0.057
1.684ValGln: 1.684 ± 0.029
6.169ValArg: 6.169 ± 0.07
5.021ValSer: 5.021 ± 0.049
7.038ValThr: 7.038 ± 0.073
9.186ValVal: 9.186 ± 0.109
1.255ValTrp: 1.255 ± 0.032
1.728ValTyr: 1.728 ± 0.032
0.0ValXaa: 0.0 ± 0.0
Trp
1.437TrpAla: 1.437 ± 0.028
0.182TrpCys: 0.182 ± 0.01
0.816TrpAsp: 0.816 ± 0.025
0.759TrpGlu: 0.759 ± 0.022
0.584TrpPhe: 0.584 ± 0.021
1.016TrpGly: 1.016 ± 0.028
0.449TrpHis: 0.449 ± 0.019
0.629TrpIle: 0.629 ± 0.019
0.239TrpLys: 0.239 ± 0.012
1.939TrpLeu: 1.939 ± 0.039
0.323TrpMet: 0.323 ± 0.014
0.418TrpAsn: 0.418 ± 0.017
0.897TrpPro: 0.897 ± 0.026
0.56TrpGln: 0.56 ± 0.019
1.983TrpArg: 1.983 ± 0.036
0.979TrpSer: 0.979 ± 0.026
0.974TrpThr: 0.974 ± 0.025
0.997TrpVal: 0.997 ± 0.024
0.518TrpTrp: 0.518 ± 0.019
0.419TrpTyr: 0.419 ± 0.018
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.347TyrAla: 2.347 ± 0.044
0.181TyrCys: 0.181 ± 0.011
1.425TyrAsp: 1.425 ± 0.034
1.081TyrGlu: 1.081 ± 0.026
0.645TyrPhe: 0.645 ± 0.021
2.08TyrGly: 2.08 ± 0.042
0.485TyrHis: 0.485 ± 0.016
0.577TyrIle: 0.577 ± 0.021
0.266TyrLys: 0.266 ± 0.015
2.256TyrLeu: 2.256 ± 0.037
0.267TyrMet: 0.267 ± 0.013
0.398TyrAsn: 0.398 ± 0.018
1.168TyrPro: 1.168 ± 0.027
0.591TyrGln: 0.591 ± 0.022
2.246TyrArg: 2.246 ± 0.042
0.98TyrSer: 0.98 ± 0.026
1.253TyrThr: 1.253 ± 0.027
1.587TyrVal: 1.587 ± 0.035
0.349TyrTrp: 0.349 ± 0.016
0.411TyrTyr: 0.411 ± 0.018
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5212 proteins (1617362 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski