Amino acid dipepetide frequency for Macrophomina phaseolina tobamo-like virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.82AlaAla: 4.82 ± 1.88
0.438AlaCys: 0.438 ± 0.142
2.41AlaAsp: 2.41 ± 0.778
4.82AlaGlu: 4.82 ± 2.0
3.506AlaPhe: 3.506 ± 0.472
2.41AlaGly: 2.41 ± 1.129
1.096AlaHis: 1.096 ± 0.43
2.41AlaIle: 2.41 ± 0.129
7.011AlaLys: 7.011 ± 0.383
4.601AlaLeu: 4.601 ± 0.46
1.753AlaMet: 1.753 ± 0.191
1.753AlaAsn: 1.753 ± 1.05
2.629AlaPro: 2.629 ± 0.82
2.41AlaGln: 2.41 ± 0.428
3.067AlaArg: 3.067 ± 0.24
4.163AlaSer: 4.163 ± 0.595
3.944AlaThr: 3.944 ± 0.959
7.011AlaVal: 7.011 ± 0.322
0.657AlaTrp: 0.657 ± 0.426
2.629AlaTyr: 2.629 ± 0.815
0.219AlaXaa: 0.219 ± 0.146
Cys
2.41CysAla: 2.41 ± 0.749
0.438CysCys: 0.438 ± 0.142
0.657CysAsp: 0.657 ± 0.426
0.438CysGlu: 0.438 ± 0.142
1.534CysPhe: 1.534 ± 0.474
0.876CysGly: 0.876 ± 0.306
0.438CysHis: 0.438 ± 0.142
0.657CysIle: 0.657 ± 0.323
0.0CysLys: 0.0 ± 0.0
0.438CysLeu: 0.438 ± 0.142
0.0CysMet: 0.0 ± 0.0
0.438CysAsn: 0.438 ± 0.142
0.657CysPro: 0.657 ± 0.426
0.876CysGln: 0.876 ± 0.407
0.438CysArg: 0.438 ± 0.142
0.876CysSer: 0.876 ± 0.348
0.438CysThr: 0.438 ± 0.142
1.096CysVal: 1.096 ± 0.342
0.0CysTrp: 0.0 ± 0.0
0.876CysTyr: 0.876 ± 0.283
0.0CysXaa: 0.0 ± 0.0
Asp
6.135AspAla: 6.135 ± 1.982
1.972AspCys: 1.972 ± 0.611
2.848AspAsp: 2.848 ± 0.731
3.506AspGlu: 3.506 ± 0.362
3.944AspPhe: 3.944 ± 1.198
3.067AspGly: 3.067 ± 0.349
0.876AspHis: 0.876 ± 0.283
2.848AspIle: 2.848 ± 1.218
3.506AspLys: 3.506 ± 0.362
4.163AspLeu: 4.163 ± 0.597
0.219AspMet: 0.219 ± 0.146
2.191AspAsn: 2.191 ± 0.401
2.191AspPro: 2.191 ± 0.47
1.753AspGln: 1.753 ± 0.818
5.478AspArg: 5.478 ± 0.607
3.944AspSer: 3.944 ± 0.888
4.601AspThr: 4.601 ± 0.446
3.506AspVal: 3.506 ± 0.71
1.315AspTrp: 1.315 ± 0.415
4.382AspTyr: 4.382 ± 0.803
0.0AspXaa: 0.0 ± 0.0
Glu
3.506GluAla: 3.506 ± 2.588
0.438GluCys: 0.438 ± 0.293
1.972GluAsp: 1.972 ± 0.497
2.191GluGlu: 2.191 ± 1.268
5.039GluPhe: 5.039 ± 1.194
3.067GluGly: 3.067 ± 1.23
0.876GluHis: 0.876 ± 0.407
3.506GluIle: 3.506 ± 0.86
3.067GluLys: 3.067 ± 1.641
4.82GluLeu: 4.82 ± 0.258
0.657GluMet: 0.657 ± 0.426
2.191GluAsn: 2.191 ± 0.684
4.163GluPro: 4.163 ± 0.774
1.753GluGln: 1.753 ± 0.566
3.944GluArg: 3.944 ± 0.493
2.848GluSer: 2.848 ± 0.554
3.287GluThr: 3.287 ± 0.615
5.916GluVal: 5.916 ± 1.197
0.657GluTrp: 0.657 ± 0.932
2.191GluTyr: 2.191 ± 0.856
0.0GluXaa: 0.0 ± 0.0
Phe
2.629PheAla: 2.629 ± 0.637
0.438PheCys: 0.438 ± 0.293
3.506PheAsp: 3.506 ± 0.839
3.287PheGlu: 3.287 ± 0.521
1.315PhePhe: 1.315 ± 0.276
5.697PheGly: 5.697 ± 0.404
1.534PheHis: 1.534 ± 0.613
2.41PheIle: 2.41 ± 0.785
2.629PheLys: 2.629 ± 0.165
3.506PheLeu: 3.506 ± 0.472
1.315PheMet: 1.315 ± 0.425
1.315PheAsn: 1.315 ± 1.133
1.972PhePro: 1.972 ± 0.611
1.534PheGln: 1.534 ± 0.45
1.534PheArg: 1.534 ± 0.613
5.259PheSer: 5.259 ± 0.764
4.601PheThr: 4.601 ± 0.889
4.82PheVal: 4.82 ± 0.875
0.0PheTrp: 0.0 ± 0.0
0.876PheTyr: 0.876 ± 0.283
0.0PheXaa: 0.0 ± 0.0
Gly
3.067GlyAla: 3.067 ± 0.546
1.096GlyCys: 1.096 ± 0.282
3.725GlyAsp: 3.725 ± 0.808
2.848GlyGlu: 2.848 ± 0.888
5.039GlyPhe: 5.039 ± 0.616
5.478GlyGly: 5.478 ± 0.669
0.876GlyHis: 0.876 ± 0.306
5.259GlyIle: 5.259 ± 1.288
6.792GlyLys: 6.792 ± 0.549
2.41GlyLeu: 2.41 ± 0.608
1.534GlyMet: 1.534 ± 0.307
3.725GlyAsn: 3.725 ± 0.15
2.629GlyPro: 2.629 ± 0.871
1.753GlyGln: 1.753 ± 1.05
4.163GlyArg: 4.163 ± 0.99
6.573GlySer: 6.573 ± 0.407
2.848GlyThr: 2.848 ± 0.202
4.601GlyVal: 4.601 ± 1.792
0.438GlyTrp: 0.438 ± 0.142
3.287GlyTyr: 3.287 ± 0.19
0.0GlyXaa: 0.0 ± 0.0
His
0.657HisAla: 0.657 ± 0.789
0.0HisCys: 0.0 ± 0.0
1.096HisAsp: 1.096 ± 0.404
0.438HisGlu: 0.438 ± 0.825
1.972HisPhe: 1.972 ± 0.382
1.753HisGly: 1.753 ± 0.566
0.438HisHis: 0.438 ± 0.142
0.219HisIle: 0.219 ± 0.49
1.096HisLys: 1.096 ± 0.43
1.315HisLeu: 1.315 ± 0.369
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.096HisPro: 1.096 ± 0.342
0.0HisGln: 0.0 ± 0.0
0.438HisArg: 0.438 ± 0.142
2.41HisSer: 2.41 ± 0.552
0.876HisThr: 0.876 ± 0.283
1.753HisVal: 1.753 ± 0.269
1.315HisTrp: 1.315 ± 0.425
0.657HisTyr: 0.657 ± 0.222
0.0HisXaa: 0.0 ± 0.0
Ile
3.725IleAla: 3.725 ± 0.458
0.657IleCys: 0.657 ± 0.426
6.354IleAsp: 6.354 ± 0.518
3.067IleGlu: 3.067 ± 0.657
2.191IlePhe: 2.191 ± 0.856
3.287IleGly: 3.287 ± 0.521
0.657IleHis: 0.657 ± 0.222
3.506IleIle: 3.506 ± 0.362
2.191IleLys: 2.191 ± 1.243
3.725IleLeu: 3.725 ± 1.156
0.657IleMet: 0.657 ± 0.236
1.315IleAsn: 1.315 ± 0.394
3.067IlePro: 3.067 ± 0.721
2.191IleGln: 2.191 ± 0.401
3.067IleArg: 3.067 ± 0.546
1.534IleSer: 1.534 ± 0.565
4.382IleThr: 4.382 ± 0.443
2.191IleVal: 2.191 ± 0.931
0.0IleTrp: 0.0 ± 0.0
1.534IleTyr: 1.534 ± 0.43
0.0IleXaa: 0.0 ± 0.0
Lys
3.287LysAla: 3.287 ± 1.266
0.657LysCys: 0.657 ± 0.426
2.41LysAsp: 2.41 ± 0.129
2.191LysGlu: 2.191 ± 0.47
2.41LysPhe: 2.41 ± 0.749
6.573LysGly: 6.573 ± 0.407
1.315LysHis: 1.315 ± 0.276
3.287LysIle: 3.287 ± 1.048
3.067LysLys: 3.067 ± 1.634
3.287LysLeu: 3.287 ± 0.615
1.534LysMet: 1.534 ± 1.387
1.972LysAsn: 1.972 ± 0.497
3.067LysPro: 3.067 ± 0.873
1.753LysGln: 1.753 ± 0.815
4.82LysArg: 4.82 ± 0.883
4.382LysSer: 4.382 ± 1.088
3.725LysThr: 3.725 ± 0.684
6.135LysVal: 6.135 ± 1.281
0.876LysTrp: 0.876 ± 0.407
1.753LysTyr: 1.753 ± 0.59
0.0LysXaa: 0.0 ± 0.0
Leu
4.601LeuAla: 4.601 ± 0.636
1.315LeuCys: 1.315 ± 0.276
7.669LeuAsp: 7.669 ± 1.471
4.601LeuGlu: 4.601 ± 1.419
3.287LeuPhe: 3.287 ± 1.266
6.354LeuGly: 6.354 ± 1.084
0.438LeuHis: 0.438 ± 0.62
3.506LeuIle: 3.506 ± 1.165
3.067LeuLys: 3.067 ± 0.873
5.697LeuLeu: 5.697 ± 1.117
0.657LeuMet: 0.657 ± 0.222
2.41LeuAsn: 2.41 ± 0.871
6.135LeuPro: 6.135 ± 1.905
2.41LeuGln: 2.41 ± 0.552
5.039LeuArg: 5.039 ± 0.672
5.916LeuSer: 5.916 ± 1.197
6.792LeuThr: 6.792 ± 1.583
7.23LeuVal: 7.23 ± 1.577
1.096LeuTrp: 1.096 ± 0.342
2.848LeuTyr: 2.848 ± 0.674
0.0LeuXaa: 0.0 ± 0.0
Met
1.972MetAla: 1.972 ± 0.729
0.0MetCys: 0.0 ± 0.0
1.753MetAsp: 1.753 ± 0.559
0.876MetGlu: 0.876 ± 0.306
1.096MetPhe: 1.096 ± 0.485
1.096MetGly: 1.096 ± 0.282
0.657MetHis: 0.657 ± 0.426
1.972MetIle: 1.972 ± 0.382
0.219MetLys: 0.219 ± 0.412
1.534MetLeu: 1.534 ± 0.436
0.219MetMet: 0.219 ± 0.146
0.876MetAsn: 0.876 ± 0.283
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
0.438MetArg: 0.438 ± 0.466
1.972MetSer: 1.972 ± 0.79
0.657MetThr: 0.657 ± 0.567
2.848MetVal: 2.848 ± 0.571
0.0MetTrp: 0.0 ± 0.0
1.096MetTyr: 1.096 ± 0.404
0.0MetXaa: 0.0 ± 0.0
Asn
1.972AsnAla: 1.972 ± 0.181
0.876AsnCys: 0.876 ± 0.283
1.096AsnAsp: 1.096 ± 0.342
0.657AsnGlu: 0.657 ± 0.222
1.753AsnPhe: 1.753 ± 0.43
3.506AsnGly: 3.506 ± 0.768
0.438AsnHis: 0.438 ± 0.142
0.438AsnIle: 0.438 ± 0.389
2.191AsnLys: 2.191 ± 0.56
2.41AsnLeu: 2.41 ± 0.129
1.315AsnMet: 1.315 ± 0.443
0.657AsnAsn: 0.657 ± 0.567
1.534AsnPro: 1.534 ± 0.701
0.438AsnGln: 0.438 ± 0.142
1.096AsnArg: 1.096 ± 0.873
2.191AsnSer: 2.191 ± 0.401
1.534AsnThr: 1.534 ± 0.614
6.135AsnVal: 6.135 ± 1.029
0.219AsnTrp: 0.219 ± 0.146
2.191AsnTyr: 2.191 ± 0.71
0.0AsnXaa: 0.0 ± 0.0
Pro
2.848ProAla: 2.848 ± 0.701
0.657ProCys: 0.657 ± 0.222
2.41ProAsp: 2.41 ± 1.716
1.972ProGlu: 1.972 ± 0.382
1.534ProPhe: 1.534 ± 0.43
3.944ProGly: 3.944 ± 0.772
0.438ProHis: 0.438 ± 0.142
2.191ProIle: 2.191 ± 0.566
2.848ProLys: 2.848 ± 1.225
3.287ProLeu: 3.287 ± 0.683
1.753ProMet: 1.753 ± 0.43
0.438ProAsn: 0.438 ± 0.293
1.096ProPro: 1.096 ± 0.84
0.438ProGln: 0.438 ± 0.98
4.382ProArg: 4.382 ± 0.53
7.011ProSer: 7.011 ± 0.827
3.506ProThr: 3.506 ± 1.574
4.82ProVal: 4.82 ± 0.897
0.219ProTrp: 0.219 ± 0.412
0.876ProTyr: 0.876 ± 0.407
0.0ProXaa: 0.0 ± 0.0
Gln
3.067GlnAla: 3.067 ± 0.702
0.0GlnCys: 0.0 ± 0.0
1.315GlnAsp: 1.315 ± 0.864
3.067GlnGlu: 3.067 ± 0.546
1.534GlnPhe: 1.534 ± 0.34
1.096GlnGly: 1.096 ± 0.404
0.219GlnHis: 0.219 ± 0.49
1.972GlnIle: 1.972 ± 0.548
1.972GlnLys: 1.972 ± 0.988
3.287GlnLeu: 3.287 ± 0.762
0.0GlnMet: 0.0 ± 0.0
1.972GlnAsn: 1.972 ± 0.382
1.753GlnPro: 1.753 ± 1.293
1.972GlnGln: 1.972 ± 0.497
1.753GlnArg: 1.753 ± 0.314
1.972GlnSer: 1.972 ± 0.611
3.287GlnThr: 3.287 ± 0.82
1.315GlnVal: 1.315 ± 0.737
0.657GlnTrp: 0.657 ± 0.323
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.287ArgAla: 3.287 ± 0.615
0.0ArgCys: 0.0 ± 0.0
3.725ArgAsp: 3.725 ± 0.324
5.039ArgGlu: 5.039 ± 1.388
2.191ArgPhe: 2.191 ± 0.668
3.725ArgGly: 3.725 ± 1.552
2.629ArgHis: 2.629 ± 0.603
3.506ArgIle: 3.506 ± 1.084
2.41ArgLys: 2.41 ± 0.552
6.354ArgLeu: 6.354 ± 1.295
1.534ArgMet: 1.534 ± 0.436
2.629ArgAsn: 2.629 ± 0.165
3.287ArgPro: 3.287 ± 0.521
1.753ArgGln: 1.753 ± 0.445
5.039ArgArg: 5.039 ± 0.725
3.506ArgSer: 3.506 ± 0.537
5.916ArgThr: 5.916 ± 0.622
5.697ArgVal: 5.697 ± 1.451
0.876ArgTrp: 0.876 ± 0.306
0.876ArgTyr: 0.876 ± 0.407
0.0ArgXaa: 0.0 ± 0.0
Ser
2.629SerAla: 2.629 ± 1.294
1.315SerCys: 1.315 ± 0.425
5.916SerAsp: 5.916 ± 1.475
5.478SerGlu: 5.478 ± 0.608
4.382SerPhe: 4.382 ± 0.991
4.163SerGly: 4.163 ± 0.546
1.753SerHis: 1.753 ± 0.566
1.315SerIle: 1.315 ± 0.415
3.725SerLys: 3.725 ± 0.847
8.107SerLeu: 8.107 ± 1.86
2.41SerMet: 2.41 ± 0.609
3.506SerAsn: 3.506 ± 0.362
2.191SerPro: 2.191 ± 0.789
1.972SerGln: 1.972 ± 1.466
2.41SerArg: 2.41 ± 0.591
3.944SerSer: 3.944 ± 1.791
4.163SerThr: 4.163 ± 0.58
11.832SerVal: 11.832 ± 1.726
1.096SerTrp: 1.096 ± 0.342
3.506SerTyr: 3.506 ± 0.683
0.0SerXaa: 0.0 ± 0.0
Thr
4.82ThrAla: 4.82 ± 0.883
0.0ThrCys: 0.0 ± 0.0
3.506ThrAsp: 3.506 ± 0.539
4.163ThrGlu: 4.163 ± 0.943
2.191ThrPhe: 2.191 ± 1.37
2.191ThrGly: 2.191 ± 1.332
0.657ThrHis: 0.657 ± 0.323
4.163ThrIle: 4.163 ± 1.007
3.944ThrLys: 3.944 ± 0.504
6.573ThrLeu: 6.573 ± 0.586
0.657ThrMet: 0.657 ± 0.426
1.096ThrAsn: 1.096 ± 0.355
2.848ThrPro: 2.848 ± 0.888
2.629ThrGln: 2.629 ± 1.294
3.725ThrArg: 3.725 ± 0.435
8.326ThrSer: 8.326 ± 1.576
5.478ThrThr: 5.478 ± 2.043
8.326ThrVal: 8.326 ± 1.416
1.096ThrTrp: 1.096 ± 0.355
1.753ThrTyr: 1.753 ± 0.314
0.0ThrXaa: 0.0 ± 0.0
Val
7.011ValAla: 7.011 ± 1.74
1.534ValCys: 1.534 ± 0.43
6.792ValAsp: 6.792 ± 0.784
5.697ValGlu: 5.697 ± 0.699
1.972ValPhe: 1.972 ± 0.497
7.23ValGly: 7.23 ± 1.638
1.972ValHis: 1.972 ± 0.386
3.944ValIle: 3.944 ± 1.145
5.916ValLys: 5.916 ± 1.475
8.983ValLeu: 8.983 ± 1.288
1.534ValMet: 1.534 ± 0.474
3.725ValAsn: 3.725 ± 0.817
4.382ValPro: 4.382 ± 0.538
3.944ValGln: 3.944 ± 0.493
8.326ValArg: 8.326 ± 2.063
5.916ValSer: 5.916 ± 0.528
5.478ValThr: 5.478 ± 1.734
6.354ValVal: 6.354 ± 0.885
0.438ValTrp: 0.438 ± 0.142
2.191ValTyr: 2.191 ± 0.566
0.0ValXaa: 0.0 ± 0.0
Trp
0.438TrpAla: 0.438 ± 0.142
0.0TrpCys: 0.0 ± 0.0
0.876TrpAsp: 0.876 ± 0.348
0.657TrpGlu: 0.657 ± 0.426
1.096TrpPhe: 1.096 ± 0.342
0.438TrpGly: 0.438 ± 0.62
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.876TrpLys: 0.876 ± 0.728
2.41TrpLeu: 2.41 ± 0.465
0.219TrpMet: 0.219 ± 0.146
0.219TrpAsn: 0.219 ± 0.412
0.219TrpPro: 0.219 ± 0.49
0.657TrpGln: 0.657 ± 0.323
0.657TrpArg: 0.657 ± 0.222
0.657TrpSer: 0.657 ± 0.222
1.096TrpThr: 1.096 ± 0.404
0.657TrpVal: 0.657 ± 0.323
0.219TrpTrp: 0.219 ± 0.412
0.657TrpTyr: 0.657 ± 0.222
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.876TyrAla: 0.876 ± 0.283
1.753TyrCys: 1.753 ± 0.566
2.191TyrAsp: 2.191 ± 0.784
1.096TyrGlu: 1.096 ± 0.941
2.191TyrPhe: 2.191 ± 0.188
2.191TyrGly: 2.191 ± 0.221
0.219TyrHis: 0.219 ± 0.146
2.41TyrIle: 2.41 ± 0.129
1.972TyrLys: 1.972 ± 0.611
4.163TyrLeu: 4.163 ± 0.774
1.096TyrMet: 1.096 ± 0.447
0.219TyrAsn: 0.219 ± 0.146
1.753TyrPro: 1.753 ± 0.314
1.972TyrGln: 1.972 ± 0.382
4.163TyrArg: 4.163 ± 1.497
2.41TyrSer: 2.41 ± 0.609
1.534TyrThr: 1.534 ± 0.43
1.096TyrVal: 1.096 ± 0.282
0.876TyrTrp: 0.876 ± 0.283
0.876TyrTyr: 0.876 ± 0.407
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.219XaaAsp: 0.219 ± 0.146
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (4565 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski