Amino acid dipepetide frequency for Mola mola (Ocean sunfish) (Tetraodon mola)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.861AlaAla: 5.861 ± 0.035	1.406AlaCys: 1.406 ± 0.013	3.105AlaAsp: 3.105 ± 0.017	4.325AlaGlu: 4.325 ± 0.024	2.519AlaPhe: 2.519 ± 0.016	4.29AlaGly: 4.29 ± 0.026	1.542AlaHis: 1.542 ± 0.011	2.838AlaIle: 2.838 ± 0.015	3.328AlaLys: 3.328 ± 0.021	6.583AlaLeu: 6.583 ± 0.028	1.599AlaMet: 1.599 ± 0.011	2.148AlaAsn: 2.148 ± 0.013	3.204AlaPro: 3.204 ± 0.02	2.807AlaGln: 2.807 ± 0.018	3.112AlaArg: 3.112 ± 0.016	5.195AlaSer: 5.195 ± 0.021	3.457AlaThr: 3.457 ± 0.018	4.919AlaVal: 4.919 ± 0.025	0.69AlaTrp: 0.69 ± 0.007	1.578AlaTyr: 1.578 ± 0.012	0.007AlaXaa: 0.007 ± 0.001
Cys	1.3CysAla: 1.3 ± 0.011	0.77CysCys: 0.77 ± 0.009	1.177CysAsp: 1.177 ± 0.015	1.276CysGlu: 1.276 ± 0.015	1.049CysPhe: 1.049 ± 0.011	1.691CysGly: 1.691 ± 0.018	0.742CysHis: 0.742 ± 0.008	1.06CysIle: 1.06 ± 0.011	1.23CysLys: 1.23 ± 0.013	2.457CysLeu: 2.457 ± 0.017	0.525CysMet: 0.525 ± 0.007	0.925CysAsn: 0.925 ± 0.01	1.382CysPro: 1.382 ± 0.014	1.106CysGln: 1.106 ± 0.012	1.398CysArg: 1.398 ± 0.011	2.267CysSer: 2.267 ± 0.019	1.271CysThr: 1.271 ± 0.011	1.78CysVal: 1.78 ± 0.015	0.35CysTrp: 0.35 ± 0.005	0.699CysTyr: 0.699 ± 0.008	0.001CysXaa: 0.001 ± 0.0
Asp	2.885AspAla: 2.885 ± 0.017	1.195AspCys: 1.195 ± 0.014	2.897AspAsp: 2.897 ± 0.022	3.501AspGlu: 3.501 ± 0.021	2.185AspPhe: 2.185 ± 0.011	3.572AspGly: 3.572 ± 0.023	1.176AspHis: 1.176 ± 0.008	2.786AspIle: 2.786 ± 0.015	2.638AspLys: 2.638 ± 0.018	4.86AspLeu: 4.86 ± 0.021	1.316AspMet: 1.316 ± 0.012	1.996AspAsn: 1.996 ± 0.014	2.704AspPro: 2.704 ± 0.014	1.829AspGln: 1.829 ± 0.012	2.7AspArg: 2.7 ± 0.019	4.223AspSer: 4.223 ± 0.023	2.597AspThr: 2.597 ± 0.013	3.268AspVal: 3.268 ± 0.019	0.714AspTrp: 0.714 ± 0.008	1.57AspTyr: 1.57 ± 0.011	0.003AspXaa: 0.003 ± 0.0
Glu	4.479GluAla: 4.479 ± 0.025	1.272GluCys: 1.272 ± 0.015	4.032GluAsp: 4.032 ± 0.022	6.876GluGlu: 6.876 ± 0.051	1.973GluPhe: 1.973 ± 0.012	3.949GluGly: 3.949 ± 0.02	1.434GluHis: 1.434 ± 0.011	2.835GluIle: 2.835 ± 0.019	4.315GluLys: 4.315 ± 0.028	6.091GluLeu: 6.091 ± 0.031	1.677GluMet: 1.677 ± 0.013	2.662GluAsn: 2.662 ± 0.016	2.558GluPro: 2.558 ± 0.017	2.949GluGln: 2.949 ± 0.02	4.064GluArg: 4.064 ± 0.024	4.047GluSer: 4.047 ± 0.023	3.159GluThr: 3.159 ± 0.017	4.243GluVal: 4.243 ± 0.019	0.691GluTrp: 0.691 ± 0.007	1.623GluTyr: 1.623 ± 0.011	0.005GluXaa: 0.005 ± 0.001
Phe	2.075PheAla: 2.075 ± 0.013	1.096PheCys: 1.096 ± 0.01	1.843PheAsp: 1.843 ± 0.01	1.896PheGlu: 1.896 ± 0.013	1.923PhePhe: 1.923 ± 0.017	2.352PheGly: 2.352 ± 0.017	1.126PheHis: 1.126 ± 0.011	2.125PheIle: 2.125 ± 0.015	1.878PheLys: 1.878 ± 0.013	4.253PheLeu: 4.253 ± 0.017	0.895PheMet: 0.895 ± 0.009	1.59PheAsn: 1.59 ± 0.01	1.939PhePro: 1.939 ± 0.013	1.679PheGln: 1.679 ± 0.011	1.983PheArg: 1.983 ± 0.012	3.643PheSer: 3.643 ± 0.019	2.436PheThr: 2.436 ± 0.016	2.448PheVal: 2.448 ± 0.015	0.504PheTrp: 0.504 ± 0.007	1.322PheTyr: 1.322 ± 0.012	0.004PheXaa: 0.004 ± 0.0
Gly	3.944GlyAla: 3.944 ± 0.027	1.369GlyCys: 1.369 ± 0.013	3.182GlyAsp: 3.182 ± 0.017	3.987GlyGlu: 3.987 ± 0.025	2.517GlyPhe: 2.517 ± 0.016	5.056GlyGly: 5.056 ± 0.04	1.696GlyHis: 1.696 ± 0.013	2.714GlyIle: 2.714 ± 0.015	3.567GlyLys: 3.567 ± 0.02	5.615GlyLeu: 5.615 ± 0.024	1.476GlyMet: 1.476 ± 0.011	2.505GlyAsn: 2.505 ± 0.017	3.147GlyPro: 3.147 ± 0.039	2.716GlyGln: 2.716 ± 0.017	3.629GlyArg: 3.629 ± 0.021	5.449GlySer: 5.449 ± 0.027	3.426GlyThr: 3.426 ± 0.02	4.035GlyVal: 4.035 ± 0.02	0.822GlyTrp: 0.822 ± 0.008	1.896GlyTyr: 1.896 ± 0.015	0.008GlyXaa: 0.008 ± 0.001
His	1.385HisAla: 1.385 ± 0.012	0.84HisCys: 0.84 ± 0.009	0.998HisAsp: 0.998 ± 0.009	1.192HisGlu: 1.192 ± 0.01	1.185HisPhe: 1.185 ± 0.01	1.593HisGly: 1.593 ± 0.013	1.028HisHis: 1.028 ± 0.011	1.414HisIle: 1.414 ± 0.012	1.311HisLys: 1.311 ± 0.01	2.822HisLeu: 2.822 ± 0.014	0.712HisMet: 0.712 ± 0.008	1.082HisAsn: 1.082 ± 0.01	1.571HisPro: 1.571 ± 0.011	1.228HisGln: 1.228 ± 0.011	1.681HisArg: 1.681 ± 0.011	2.447HisSer: 2.447 ± 0.015	1.695HisThr: 1.695 ± 0.014	1.57HisVal: 1.57 ± 0.01	0.381HisTrp: 0.381 ± 0.004	0.897HisTyr: 0.897 ± 0.009	0.002HisXaa: 0.002 ± 0.0
Ile	2.616IleAla: 2.616 ± 0.014	1.183IleCys: 1.183 ± 0.012	2.165IleAsp: 2.165 ± 0.013	2.41IleGlu: 2.41 ± 0.016	2.024IlePhe: 2.024 ± 0.015	2.423IleGly: 2.423 ± 0.014	1.372IleHis: 1.372 ± 0.01	2.596IleIle: 2.596 ± 0.018	2.607IleLys: 2.607 ± 0.017	4.595IleLeu: 4.595 ± 0.02	1.153IleMet: 1.153 ± 0.01	2.062IleAsn: 2.062 ± 0.013	2.476IlePro: 2.476 ± 0.014	2.243IleGln: 2.243 ± 0.015	2.497IleArg: 2.497 ± 0.014	3.95IleSer: 3.95 ± 0.022	2.883IleThr: 2.883 ± 0.017	2.756IleVal: 2.756 ± 0.016	0.519IleTrp: 0.519 ± 0.006	1.552IleTyr: 1.552 ± 0.011	0.003IleXaa: 0.003 ± 0.0
Lys	3.603LysAla: 3.603 ± 0.022	1.103LysCys: 1.103 ± 0.011	3.065LysAsp: 3.065 ± 0.017	4.355LysGlu: 4.355 ± 0.029	1.672LysPhe: 1.672 ± 0.012	3.14LysGly: 3.14 ± 0.024	1.45LysHis: 1.45 ± 0.01	2.553LysIle: 2.553 ± 0.015	4.201LysLys: 4.201 ± 0.03	4.988LysLeu: 4.988 ± 0.024	1.509LysMet: 1.509 ± 0.011	2.282LysAsn: 2.282 ± 0.013	2.724LysPro: 2.724 ± 0.021	2.475LysGln: 2.475 ± 0.019	3.358LysArg: 3.358 ± 0.016	3.606LysSer: 3.606 ± 0.02	3.082LysThr: 3.082 ± 0.019	3.626LysVal: 3.626 ± 0.021	0.599LysTrp: 0.599 ± 0.008	1.555LysTyr: 1.555 ± 0.012	0.004LysXaa: 0.004 ± 0.001
Leu	6.233LeuAla: 6.233 ± 0.025	2.518LeuCys: 2.518 ± 0.016	4.884LeuAsp: 4.884 ± 0.021	6.246LeuGlu: 6.246 ± 0.036	3.777LeuPhe: 3.777 ± 0.022	5.308LeuGly: 5.308 ± 0.023	2.85LeuHis: 2.85 ± 0.017	4.109LeuIle: 4.109 ± 0.02	5.582LeuLys: 5.582 ± 0.025	10.574LeuLeu: 10.574 ± 0.042	2.245LeuMet: 2.245 ± 0.014	3.738LeuAsn: 3.738 ± 0.017	5.284LeuPro: 5.284 ± 0.024	5.424LeuGln: 5.424 ± 0.027	5.784LeuArg: 5.784 ± 0.024	8.556LeuSer: 8.556 ± 0.03	5.402LeuThr: 5.402 ± 0.018	5.822LeuVal: 5.822 ± 0.026	1.164LeuTrp: 1.164 ± 0.01	2.807LeuTyr: 2.807 ± 0.016	0.008LeuXaa: 0.008 ± 0.001
Met	1.911MetAla: 1.911 ± 0.014	0.553MetCys: 0.553 ± 0.007	1.432MetAsp: 1.432 ± 0.01	1.941MetGlu: 1.941 ± 0.013	0.956MetPhe: 0.956 ± 0.01	1.451MetGly: 1.451 ± 0.01	0.519MetHis: 0.519 ± 0.007	0.956MetIle: 0.956 ± 0.009	1.483MetLys: 1.483 ± 0.011	2.211MetLeu: 2.211 ± 0.014	0.707MetMet: 0.707 ± 0.007	0.942MetAsn: 0.942 ± 0.009	1.058MetPro: 1.058 ± 0.009	0.993MetGln: 0.993 ± 0.009	1.236MetArg: 1.236 ± 0.009	1.919MetSer: 1.919 ± 0.01	1.316MetThr: 1.316 ± 0.011	1.635MetVal: 1.635 ± 0.012	0.282MetTrp: 0.282 ± 0.004	0.679MetTyr: 0.679 ± 0.008	0.002MetXaa: 0.002 ± 0.0
Asn	2.2AsnAla: 2.2 ± 0.013	0.952AsnCys: 0.952 ± 0.01	1.711AsnAsp: 1.711 ± 0.013	2.019AsnGlu: 2.019 ± 0.012	1.531AsnPhe: 1.531 ± 0.012	2.701AsnGly: 2.701 ± 0.021	1.04AsnHis: 1.04 ± 0.009	2.303AsnIle: 2.303 ± 0.015	2.248AsnLys: 2.248 ± 0.015	3.758AsnLeu: 3.758 ± 0.019	1.105AsnMet: 1.105 ± 0.009	1.806AsnAsn: 1.806 ± 0.014	2.245AsnPro: 2.245 ± 0.014	1.673AsnGln: 1.673 ± 0.013	1.994AsnArg: 1.994 ± 0.013	3.207AsnSer: 3.207 ± 0.017	2.278AsnThr: 2.278 ± 0.014	2.419AsnVal: 2.419 ± 0.015	0.478AsnTrp: 0.478 ± 0.007	1.234AsnTyr: 1.234 ± 0.011	0.003AsnXaa: 0.003 ± 0.0
Pro	3.781ProAla: 3.781 ± 0.023	1.138ProCys: 1.138 ± 0.013	2.744ProAsp: 2.744 ± 0.016	3.506ProGlu: 3.506 ± 0.021	1.875ProPhe: 1.875 ± 0.013	3.887ProGly: 3.887 ± 0.045	1.493ProHis: 1.493 ± 0.012	1.959ProIle: 1.959 ± 0.014	2.391ProLys: 2.391 ± 0.018	4.83ProLeu: 4.83 ± 0.024	1.026ProMet: 1.026 ± 0.009	1.918ProAsn: 1.918 ± 0.014	4.653ProPro: 4.653 ± 0.042	2.439ProGln: 2.439 ± 0.021	2.628ProArg: 2.628 ± 0.015	5.092ProSer: 5.092 ± 0.027	2.891ProThr: 2.891 ± 0.017	3.618ProVal: 3.618 ± 0.019	0.58ProTrp: 0.58 ± 0.007	1.465ProTyr: 1.465 ± 0.013	0.008ProXaa: 0.008 ± 0.001
Gln	3.016GlnAla: 3.016 ± 0.02	1.04GlnCys: 1.04 ± 0.011	2.227GlnAsp: 2.227 ± 0.016	3.245GlnGlu: 3.245 ± 0.023	1.419GlnPhe: 1.419 ± 0.009	2.688GlnGly: 2.688 ± 0.023	1.342GlnHis: 1.342 ± 0.011	1.956GlnIle: 1.956 ± 0.011	2.482GlnLys: 2.482 ± 0.016	4.567GlnLeu: 4.567 ± 0.025	1.113GlnMet: 1.113 ± 0.01	1.78GlnAsn: 1.78 ± 0.013	2.354GlnPro: 2.354 ± 0.018	3.004GlnGln: 3.004 ± 0.034	3.006GlnArg: 3.006 ± 0.02	3.276GlnSer: 3.276 ± 0.018	2.487GlnThr: 2.487 ± 0.016	2.889GlnVal: 2.889 ± 0.017	0.566GlnTrp: 0.566 ± 0.006	1.278GlnTyr: 1.278 ± 0.01	0.003GlnXaa: 0.003 ± 0.001
Arg	3.442ArgAla: 3.442 ± 0.017	1.377ArgCys: 1.377 ± 0.012	2.907ArgAsp: 2.907 ± 0.018	3.758ArgGlu: 3.758 ± 0.024	2.075ArgPhe: 2.075 ± 0.014	3.477ArgGly: 3.477 ± 0.02	1.612ArgHis: 1.612 ± 0.011	2.503ArgIle: 2.503 ± 0.015	3.396ArgLys: 3.396 ± 0.017	5.427ArgLeu: 5.427 ± 0.025	1.338ArgMet: 1.338 ± 0.01	2.153ArgAsn: 2.153 ± 0.013	2.825ArgPro: 2.825 ± 0.016	2.609ArgGln: 2.609 ± 0.016	4.272ArgArg: 4.272 ± 0.024	4.391ArgSer: 4.391 ± 0.025	2.901ArgThr: 2.901 ± 0.016	3.399ArgVal: 3.399 ± 0.017	0.732ArgTrp: 0.732 ± 0.008	1.646ArgTyr: 1.646 ± 0.01	0.005ArgXaa: 0.005 ± 0.001
Ser	5.415SerAla: 5.415 ± 0.025	2.142SerCys: 2.142 ± 0.018	4.133SerAsp: 4.133 ± 0.024	4.58SerGlu: 4.58 ± 0.019	3.298SerPhe: 3.298 ± 0.016	5.385SerGly: 5.385 ± 0.024	2.268SerHis: 2.268 ± 0.014	3.459SerIle: 3.459 ± 0.017	3.876SerLys: 3.876 ± 0.022	8.466SerLeu: 8.466 ± 0.033	1.813SerMet: 1.813 ± 0.011	2.975SerAsn: 2.975 ± 0.019	5.413SerPro: 5.413 ± 0.03	3.738SerGln: 3.738 ± 0.021	4.412SerArg: 4.412 ± 0.021	9.461SerSer: 9.461 ± 0.054	4.614SerThr: 4.614 ± 0.023	5.506SerVal: 5.506 ± 0.023	1.078SerTrp: 1.078 ± 0.011	2.271SerTyr: 2.271 ± 0.015	0.009SerXaa: 0.009 ± 0.001
Thr	3.943ThrAla: 3.943 ± 0.019	1.469ThrCys: 1.469 ± 0.016	2.817ThrAsp: 2.817 ± 0.016	3.459ThrGlu: 3.459 ± 0.017	2.27ThrPhe: 2.27 ± 0.014	3.735ThrGly: 3.735 ± 0.023	1.524ThrHis: 1.524 ± 0.014	2.56ThrIle: 2.56 ± 0.018	2.601ThrLys: 2.601 ± 0.016	5.557ThrLeu: 5.557 ± 0.024	1.261ThrMet: 1.261 ± 0.01	1.968ThrAsn: 1.968 ± 0.012	3.304ThrPro: 3.304 ± 0.022	2.285ThrGln: 2.285 ± 0.016	2.53ThrArg: 2.53 ± 0.015	4.653ThrSer: 4.653 ± 0.023	3.167ThrThr: 3.167 ± 0.022	4.288ThrVal: 4.288 ± 0.022	0.692ThrTrp: 0.692 ± 0.008	1.529ThrTyr: 1.529 ± 0.011	0.006ThrXaa: 0.006 ± 0.001
Val	4.218ValAla: 4.218 ± 0.021	1.974ValCys: 1.974 ± 0.015	3.19ValAsp: 3.19 ± 0.016	3.966ValGlu: 3.966 ± 0.02	2.906ValPhe: 2.906 ± 0.017	3.644ValGly: 3.644 ± 0.018	1.687ValHis: 1.687 ± 0.012	3.171ValIle: 3.171 ± 0.015	3.509ValLys: 3.509 ± 0.017	6.517ValLeu: 6.517 ± 0.028	1.609ValMet: 1.609 ± 0.011	2.545ValAsn: 2.545 ± 0.015	3.25ValPro: 3.25 ± 0.022	2.729ValGln: 2.729 ± 0.016	3.436ValArg: 3.436 ± 0.018	5.49ValSer: 5.49 ± 0.025	4.081ValThr: 4.081 ± 0.026	4.55ValVal: 4.55 ± 0.021	0.838ValTrp: 0.838 ± 0.008	1.96ValTyr: 1.96 ± 0.014	0.005ValXaa: 0.005 ± 0.001
Trp	0.702TrpAla: 0.702 ± 0.008	0.27TrpCys: 0.27 ± 0.006	0.676TrpAsp: 0.676 ± 0.009	0.778TrpGlu: 0.778 ± 0.008	0.505TrpPhe: 0.505 ± 0.007	0.684TrpGly: 0.684 ± 0.009	0.3TrpHis: 0.3 ± 0.005	0.596TrpIle: 0.596 ± 0.007	0.748TrpLys: 0.748 ± 0.007	1.273TrpLeu: 1.273 ± 0.011	0.378TrpMet: 0.378 ± 0.005	0.546TrpAsn: 0.546 ± 0.007	0.472TrpPro: 0.472 ± 0.006	0.517TrpGln: 0.517 ± 0.007	0.77TrpArg: 0.77 ± 0.007	0.999TrpSer: 0.999 ± 0.009	0.751TrpThr: 0.751 ± 0.008	0.765TrpVal: 0.765 ± 0.009	0.206TrpTrp: 0.206 ± 0.004	0.369TrpTyr: 0.369 ± 0.006	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.5TyrAla: 1.5 ± 0.01	0.787TyrCys: 0.787 ± 0.009	1.429TyrAsp: 1.429 ± 0.012	1.613TyrGlu: 1.613 ± 0.011	1.347TyrPhe: 1.347 ± 0.012	1.726TyrGly: 1.726 ± 0.014	0.831TyrHis: 0.831 ± 0.008	1.589TyrIle: 1.589 ± 0.012	1.553TyrLys: 1.553 ± 0.014	2.861TyrLeu: 2.861 ± 0.016	0.726TyrMet: 0.726 ± 0.007	1.279TyrAsn: 1.279 ± 0.01	1.352TyrPro: 1.352 ± 0.01	1.29TyrGln: 1.29 ± 0.011	1.75TyrArg: 1.75 ± 0.011	2.434TyrSer: 2.434 ± 0.014	1.717TyrThr: 1.717 ± 0.013	1.73TyrVal: 1.73 ± 0.013	0.419TyrTrp: 0.419 ± 0.007	1.04TyrTyr: 1.04 ± 0.01	0.002TyrXaa: 0.002 ± 0.0
Xaa	0.007XaaAla: 0.007 ± 0.001	0.002XaaCys: 0.002 ± 0.0	0.003XaaAsp: 0.003 ± 0.0	0.004XaaGlu: 0.004 ± 0.001	0.004XaaPhe: 0.004 ± 0.001	0.006XaaGly: 0.006 ± 0.001	0.003XaaHis: 0.003 ± 0.0	0.004XaaIle: 0.004 ± 0.001	0.004XaaLys: 0.004 ± 0.0	0.008XaaLeu: 0.008 ± 0.001	0.003XaaMet: 0.003 ± 0.0	0.003XaaAsn: 0.003 ± 0.0	0.006XaaPro: 0.006 ± 0.001	0.003XaaGln: 0.003 ± 0.0	0.006XaaArg: 0.006 ± 0.001	0.008XaaSer: 0.008 ± 0.001	0.005XaaThr: 0.005 ± 0.001	0.006XaaVal: 0.006 ± 0.001	0.001XaaTrp: 0.001 ± 0.0	0.002XaaTyr: 0.002 ± 0.0	1.765XaaXaa: 1.765 ± 0.094

Statistics based on 28963 proteins (14064223 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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