Amino acid dipepetide frequency for Alces alces faeces associated smacovirus MP78

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.143AlaAla: 1.143 ± 0.723
0.0AlaCys: 0.0 ± 0.0
2.286AlaAsp: 2.286 ± 1.447
2.286AlaGlu: 2.286 ± 2.175
5.714AlaPhe: 5.714 ± 1.806
4.571AlaGly: 4.571 ± 1.083
3.429AlaHis: 3.429 ± 1.452
3.429AlaIle: 3.429 ± 1.452
1.143AlaLys: 1.143 ± 1.088
3.429AlaLeu: 3.429 ± 1.452
0.0AlaMet: 0.0 ± 0.523
3.429AlaAsn: 3.429 ± 0.359
1.143AlaPro: 1.143 ± 1.088
1.143AlaGln: 1.143 ± 0.723
1.143AlaArg: 1.143 ± 0.723
2.286AlaSer: 2.286 ± 1.447
3.429AlaThr: 3.429 ± 0.359
1.143AlaVal: 1.143 ± 1.088
0.0AlaTrp: 0.0 ± 0.0
4.571AlaTyr: 4.571 ± 0.729
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.143CysAsp: 1.143 ± 1.088
1.143CysGlu: 1.143 ± 0.723
0.0CysPhe: 0.0 ± 0.0
1.143CysGly: 1.143 ± 1.088
1.143CysHis: 1.143 ± 0.723
0.0CysIle: 0.0 ± 0.0
2.286CysLys: 2.286 ± 2.175
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.143CysArg: 1.143 ± 1.088
3.429CysSer: 3.429 ± 0.359
1.143CysThr: 1.143 ± 1.088
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.143CysTyr: 1.143 ± 1.088
0.0CysXaa: 0.0 ± 0.0
Asp
1.143AspAla: 1.143 ± 0.723
0.0AspCys: 0.0 ± 0.0
6.857AspAsp: 6.857 ± 1.093
0.0AspGlu: 0.0 ± 0.0
3.429AspPhe: 3.429 ± 0.359
5.714AspGly: 5.714 ± 0.005
0.0AspHis: 0.0 ± 0.0
1.143AspIle: 1.143 ± 1.088
1.143AspLys: 1.143 ± 0.723
8.0AspLeu: 8.0 ± 3.253
1.143AspMet: 1.143 ± 0.663
5.714AspAsn: 5.714 ± 1.806
4.571AspPro: 4.571 ± 1.083
3.429AspGln: 3.429 ± 1.452
2.286AspArg: 2.286 ± 2.175
9.143AspSer: 9.143 ± 3.976
5.714AspThr: 5.714 ± 0.005
4.571AspVal: 4.571 ± 0.729
2.286AspTrp: 2.286 ± 0.364
3.429AspTyr: 3.429 ± 0.359
0.0AspXaa: 0.0 ± 0.0
Glu
3.429GluAla: 3.429 ± 3.263
0.0GluCys: 0.0 ± 0.0
2.286GluAsp: 2.286 ± 1.447
9.143GluGlu: 9.143 ± 5.08
1.143GluPhe: 1.143 ± 0.723
2.286GluGly: 2.286 ± 0.364
0.0GluHis: 0.0 ± 0.0
6.857GluIle: 6.857 ± 2.904
1.143GluLys: 1.143 ± 1.088
0.0GluLeu: 0.0 ± 0.0
0.0GluMet: 0.0 ± 0.0
2.286GluAsn: 2.286 ± 0.364
1.143GluPro: 1.143 ± 0.723
1.143GluGln: 1.143 ± 0.723
3.429GluArg: 3.429 ± 1.452
8.0GluSer: 8.0 ± 1.442
1.143GluThr: 1.143 ± 0.723
2.286GluVal: 2.286 ± 0.364
2.286GluTrp: 2.286 ± 0.364
5.714GluTyr: 5.714 ± 0.005
0.0GluXaa: 0.0 ± 0.0
Phe
5.714PheAla: 5.714 ± 3.617
1.143PheCys: 1.143 ± 1.088
2.286PheAsp: 2.286 ± 2.175
3.429PheGlu: 3.429 ± 1.452
1.143PhePhe: 1.143 ± 1.088
3.429PheGly: 3.429 ± 0.359
1.143PheHis: 1.143 ± 0.723
0.0PheIle: 0.0 ± 0.0
4.571PheLys: 4.571 ± 2.894
2.286PheLeu: 2.286 ± 2.175
1.143PheMet: 1.143 ± 0.723
1.143PheAsn: 1.143 ± 0.723
1.143PhePro: 1.143 ± 0.723
1.143PheGln: 1.143 ± 0.723
2.286PheArg: 2.286 ± 1.447
4.571PheSer: 4.571 ± 1.083
3.429PheThr: 3.429 ± 0.359
1.143PheVal: 1.143 ± 0.723
1.143PheTrp: 1.143 ± 0.723
1.143PheTyr: 1.143 ± 0.723
0.0PheXaa: 0.0 ± 0.0
Gly
2.286GlyAla: 2.286 ± 0.364
2.286GlyCys: 2.286 ± 1.447
4.571GlyAsp: 4.571 ± 0.729
4.571GlyGlu: 4.571 ± 1.083
6.857GlyPhe: 6.857 ± 2.529
3.429GlyGly: 3.429 ± 2.17
1.143GlyHis: 1.143 ± 0.723
4.571GlyIle: 4.571 ± 1.083
2.286GlyLys: 2.286 ± 2.175
4.571GlyLeu: 4.571 ± 1.083
2.286GlyMet: 2.286 ± 1.447
9.143GlyAsn: 9.143 ± 0.354
0.0GlyPro: 0.0 ± 0.0
0.0GlyGln: 0.0 ± 0.0
4.571GlyArg: 4.571 ± 2.54
5.714GlySer: 5.714 ± 3.617
1.143GlyThr: 1.143 ± 0.723
9.143GlyVal: 9.143 ± 2.165
2.286GlyTrp: 2.286 ± 1.447
3.429GlyTyr: 3.429 ± 0.359
0.0GlyXaa: 0.0 ± 0.0
His
1.143HisAla: 1.143 ± 1.088
0.0HisCys: 0.0 ± 0.0
1.143HisAsp: 1.143 ± 1.088
1.143HisGlu: 1.143 ± 0.723
0.0HisPhe: 0.0 ± 0.0
2.286HisGly: 2.286 ± 1.447
0.0HisHis: 0.0 ± 0.0
1.143HisIle: 1.143 ± 1.088
0.0HisLys: 0.0 ± 0.0
3.429HisLeu: 3.429 ± 0.359
1.143HisMet: 1.143 ± 1.088
1.143HisAsn: 1.143 ± 1.088
1.143HisPro: 1.143 ± 0.723
0.0HisGln: 0.0 ± 0.0
2.286HisArg: 2.286 ± 1.447
0.0HisSer: 0.0 ± 0.0
3.429HisThr: 3.429 ± 0.359
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
1.143HisTyr: 1.143 ± 1.088
0.0HisXaa: 0.0 ± 0.0
Ile
1.143IleAla: 1.143 ± 0.723
2.286IleCys: 2.286 ± 2.175
5.714IleAsp: 5.714 ± 0.005
2.286IleGlu: 2.286 ± 2.175
2.286IlePhe: 2.286 ± 0.364
4.571IleGly: 4.571 ± 1.083
2.286IleHis: 2.286 ± 0.364
5.714IleIle: 5.714 ± 1.816
2.286IleLys: 2.286 ± 0.364
2.286IleLeu: 2.286 ± 0.364
3.429IleMet: 3.429 ± 2.17
3.429IleAsn: 3.429 ± 0.359
1.143IlePro: 1.143 ± 1.088
2.286IleGln: 2.286 ± 0.364
3.429IleArg: 3.429 ± 3.263
4.571IleSer: 4.571 ± 0.729
5.714IleThr: 5.714 ± 1.806
1.143IleVal: 1.143 ± 0.723
0.0IleTrp: 0.0 ± 0.0
3.429IleTyr: 3.429 ± 1.452
0.0IleXaa: 0.0 ± 0.0
Lys
4.571LysAla: 4.571 ± 1.083
0.0LysCys: 0.0 ± 0.0
2.286LysAsp: 2.286 ± 0.364
1.143LysGlu: 1.143 ± 0.723
2.286LysPhe: 2.286 ± 1.447
1.143LysGly: 1.143 ± 0.723
0.0LysHis: 0.0 ± 0.0
5.714LysIle: 5.714 ± 3.627
3.429LysLys: 3.429 ± 1.452
4.571LysLeu: 4.571 ± 2.54
0.0LysMet: 0.0 ± 0.0
2.286LysAsn: 2.286 ± 2.175
0.0LysPro: 0.0 ± 0.0
1.143LysGln: 1.143 ± 0.723
2.286LysArg: 2.286 ± 2.175
2.286LysSer: 2.286 ± 0.364
5.714LysThr: 5.714 ± 3.627
2.286LysVal: 2.286 ± 1.447
1.143LysTrp: 1.143 ± 1.088
1.143LysTyr: 1.143 ± 0.723
0.0LysXaa: 0.0 ± 0.0
Leu
1.143LeuAla: 1.143 ± 0.723
1.143LeuCys: 1.143 ± 0.723
5.714LeuAsp: 5.714 ± 1.806
2.286LeuGlu: 2.286 ± 0.364
0.0LeuPhe: 0.0 ± 0.0
4.571LeuGly: 4.571 ± 2.894
2.286LeuHis: 2.286 ± 0.364
3.429LeuIle: 3.429 ± 0.359
1.143LeuLys: 1.143 ± 0.723
4.571LeuLeu: 4.571 ± 1.083
0.0LeuMet: 0.0 ± 0.0
4.571LeuAsn: 4.571 ± 2.894
4.571LeuPro: 4.571 ± 1.083
2.286LeuGln: 2.286 ± 1.447
3.429LeuArg: 3.429 ± 1.452
11.429LeuSer: 11.429 ± 1.822
8.0LeuThr: 8.0 ± 2.181
9.143LeuVal: 9.143 ± 1.457
1.143LeuTrp: 1.143 ± 0.723
5.714LeuTyr: 5.714 ± 0.005
0.0LeuXaa: 0.0 ± 0.0
Met
1.143MetAla: 1.143 ± 0.723
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
2.286MetPhe: 2.286 ± 1.447
2.286MetGly: 2.286 ± 1.447
0.0MetHis: 0.0 ± 0.0
2.286MetIle: 2.286 ± 0.364
1.143MetLys: 1.143 ± 1.088
3.429MetLeu: 3.429 ± 1.452
0.0MetMet: 0.0 ± 0.0
1.143MetAsn: 1.143 ± 0.723
1.143MetPro: 1.143 ± 0.723
1.143MetGln: 1.143 ± 1.088
0.0MetArg: 0.0 ± 0.0
0.0MetSer: 0.0 ± 0.0
1.143MetThr: 1.143 ± 0.723
1.143MetVal: 1.143 ± 1.088
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.429AsnAla: 3.429 ± 1.452
0.0AsnCys: 0.0 ± 0.0
6.857AsnAsp: 6.857 ± 1.093
1.143AsnGlu: 1.143 ± 0.723
2.286AsnPhe: 2.286 ± 0.364
8.0AsnGly: 8.0 ± 2.181
2.286AsnHis: 2.286 ± 0.364
4.571AsnIle: 4.571 ± 0.729
4.571AsnLys: 4.571 ± 0.729
3.429AsnLeu: 3.429 ± 0.359
0.0AsnMet: 0.0 ± 0.0
1.143AsnAsn: 1.143 ± 1.088
3.429AsnPro: 3.429 ± 2.17
2.286AsnGln: 2.286 ± 1.447
2.286AsnArg: 2.286 ± 0.364
6.857AsnSer: 6.857 ± 4.341
3.429AsnThr: 3.429 ± 0.359
2.286AsnVal: 2.286 ± 1.447
2.286AsnTrp: 2.286 ± 1.447
1.143AsnTyr: 1.143 ± 1.088
0.0AsnXaa: 0.0 ± 0.0
Pro
4.571ProAla: 4.571 ± 2.894
0.0ProCys: 0.0 ± 0.0
2.286ProAsp: 2.286 ± 0.364
3.429ProGlu: 3.429 ± 0.359
0.0ProPhe: 0.0 ± 0.0
0.0ProGly: 0.0 ± 0.0
2.286ProHis: 2.286 ± 1.447
3.429ProIle: 3.429 ± 2.17
1.143ProLys: 1.143 ± 0.723
1.143ProLeu: 1.143 ± 0.723
1.143ProMet: 1.143 ± 1.088
1.143ProAsn: 1.143 ± 0.723
3.429ProPro: 3.429 ± 2.17
2.286ProGln: 2.286 ± 1.447
5.714ProArg: 5.714 ± 3.627
3.429ProSer: 3.429 ± 0.359
2.286ProThr: 2.286 ± 0.364
1.143ProVal: 1.143 ± 0.723
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
1.143GlnAla: 1.143 ± 0.723
0.0GlnCys: 0.0 ± 0.0
2.286GlnAsp: 2.286 ± 0.364
3.429GlnGlu: 3.429 ± 1.452
1.143GlnPhe: 1.143 ± 0.723
2.286GlnGly: 2.286 ± 0.364
0.0GlnHis: 0.0 ± 0.0
3.429GlnIle: 3.429 ± 0.359
1.143GlnLys: 1.143 ± 1.088
2.286GlnLeu: 2.286 ± 1.447
0.0GlnMet: 0.0 ± 0.0
3.429GlnAsn: 3.429 ± 2.17
0.0GlnPro: 0.0 ± 0.0
1.143GlnGln: 1.143 ± 0.723
3.429GlnArg: 3.429 ± 1.452
3.429GlnSer: 3.429 ± 1.452
1.143GlnThr: 1.143 ± 0.723
3.429GlnVal: 3.429 ± 1.452
0.0GlnTrp: 0.0 ± 0.0
4.571GlnTyr: 4.571 ± 2.894
0.0GlnXaa: 0.0 ± 0.0
Arg
2.286ArgAla: 2.286 ± 2.175
1.143ArgCys: 1.143 ± 1.088
1.143ArgAsp: 1.143 ± 0.723
2.286ArgGlu: 2.286 ± 2.175
3.429ArgPhe: 3.429 ± 0.359
6.857ArgGly: 6.857 ± 1.093
1.143ArgHis: 1.143 ± 1.088
0.0ArgIle: 0.0 ± 0.0
4.571ArgLys: 4.571 ± 0.729
6.857ArgLeu: 6.857 ± 1.093
4.571ArgMet: 4.571 ± 0.729
2.286ArgAsn: 2.286 ± 2.175
2.286ArgPro: 2.286 ± 0.364
3.429ArgGln: 3.429 ± 3.263
0.0ArgArg: 0.0 ± 0.0
5.714ArgSer: 5.714 ± 3.627
1.143ArgThr: 1.143 ± 1.088
0.0ArgVal: 0.0 ± 0.0
1.143ArgTrp: 1.143 ± 1.088
2.286ArgTyr: 2.286 ± 2.175
0.0ArgXaa: 0.0 ± 0.0
Ser
4.571SerAla: 4.571 ± 0.729
2.286SerCys: 2.286 ± 0.364
12.571SerAsp: 12.571 ± 4.335
2.286SerGlu: 2.286 ± 1.447
2.286SerPhe: 2.286 ± 1.447
12.571SerGly: 12.571 ± 2.524
0.0SerHis: 0.0 ± 0.0
4.571SerIle: 4.571 ± 2.894
0.0SerLys: 0.0 ± 0.0
6.857SerLeu: 6.857 ± 2.529
1.143SerMet: 1.143 ± 0.723
5.714SerAsn: 5.714 ± 1.816
2.286SerPro: 2.286 ± 1.447
2.286SerGln: 2.286 ± 0.364
6.857SerArg: 6.857 ± 4.715
5.714SerSer: 5.714 ± 1.816
8.0SerThr: 8.0 ± 0.369
5.714SerVal: 5.714 ± 1.806
0.0SerTrp: 0.0 ± 0.0
5.714SerTyr: 5.714 ± 1.806
0.0SerXaa: 0.0 ± 0.0
Thr
4.571ThrAla: 4.571 ± 4.351
0.0ThrCys: 0.0 ± 0.0
4.571ThrAsp: 4.571 ± 1.083
5.714ThrGlu: 5.714 ± 1.806
3.429ThrPhe: 3.429 ± 1.452
3.429ThrGly: 3.429 ± 2.17
0.0ThrHis: 0.0 ± 0.0
2.286ThrIle: 2.286 ± 2.175
3.429ThrLys: 3.429 ± 3.263
6.857ThrLeu: 6.857 ± 2.529
0.0ThrMet: 0.0 ± 0.0
6.857ThrAsn: 6.857 ± 0.718
5.714ThrPro: 5.714 ± 1.806
4.571ThrGln: 4.571 ± 1.083
1.143ThrArg: 1.143 ± 0.723
2.286ThrSer: 2.286 ± 1.447
8.0ThrThr: 8.0 ± 2.181
3.429ThrVal: 3.429 ± 0.359
4.571ThrTrp: 4.571 ± 0.729
1.143ThrTyr: 1.143 ± 1.088
0.0ThrXaa: 0.0 ± 0.0
Val
1.143ValAla: 1.143 ± 0.723
1.143ValCys: 1.143 ± 1.088
3.429ValAsp: 3.429 ± 0.359
1.143ValGlu: 1.143 ± 0.723
2.286ValPhe: 2.286 ± 0.364
2.286ValGly: 2.286 ± 1.447
1.143ValHis: 1.143 ± 1.088
5.714ValIle: 5.714 ± 1.806
4.571ValLys: 4.571 ± 2.54
3.429ValLeu: 3.429 ± 0.359
0.0ValMet: 0.0 ± 0.0
3.429ValAsn: 3.429 ± 0.359
4.571ValPro: 4.571 ± 2.54
3.429ValGln: 3.429 ± 0.359
1.143ValArg: 1.143 ± 1.088
8.0ValSer: 8.0 ± 1.442
2.286ValThr: 2.286 ± 1.447
2.286ValVal: 2.286 ± 0.364
0.0ValTrp: 0.0 ± 0.0
3.429ValTyr: 3.429 ± 0.359
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
2.286TrpCys: 2.286 ± 2.175
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
1.143TrpGly: 1.143 ± 0.723
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.143TrpLys: 1.143 ± 0.723
2.286TrpLeu: 2.286 ± 0.364
1.143TrpMet: 1.143 ± 1.088
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.143TrpGln: 1.143 ± 0.723
2.286TrpArg: 2.286 ± 0.364
2.286TrpSer: 2.286 ± 1.447
3.429TrpThr: 3.429 ± 0.359
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.143TrpTyr: 1.143 ± 0.723
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.286TyrAla: 2.286 ± 0.364
0.0TyrCys: 0.0 ± 0.0
2.286TyrAsp: 2.286 ± 1.447
6.857TyrGlu: 6.857 ± 2.904
3.429TyrPhe: 3.429 ± 0.359
2.286TyrGly: 2.286 ± 1.447
2.286TyrHis: 2.286 ± 0.364
1.143TyrIle: 1.143 ± 1.088
2.286TyrLys: 2.286 ± 1.447
6.857TyrLeu: 6.857 ± 2.529
0.0TyrMet: 0.0 ± 0.0
3.429TyrAsn: 3.429 ± 0.359
1.143TyrPro: 1.143 ± 0.723
3.429TyrGln: 3.429 ± 1.452
3.429TyrArg: 3.429 ± 1.452
2.286TyrSer: 2.286 ± 0.364
2.286TyrThr: 2.286 ± 1.447
4.571TyrVal: 4.571 ± 2.54
0.0TyrTrp: 0.0 ± 0.0
3.429TyrTyr: 3.429 ± 2.17
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (876 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski