Amino acid dipepetide frequency for Canary circovirus (CaCV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.132AlaAla: 11.132 ± 2.055
0.0AlaCys: 0.0 ± 0.0
1.855AlaAsp: 1.855 ± 1.42
1.855AlaGlu: 1.855 ± 1.224
1.855AlaPhe: 1.855 ± 1.42
3.711AlaGly: 3.711 ± 2.448
1.855AlaHis: 1.855 ± 1.224
1.855AlaIle: 1.855 ± 1.224
5.566AlaLys: 5.566 ± 1.028
9.276AlaLeu: 9.276 ± 3.476
1.855AlaMet: 1.855 ± 1.224
5.566AlaAsn: 5.566 ± 4.261
3.711AlaPro: 3.711 ± 0.196
0.0AlaGln: 0.0 ± 0.0
9.276AlaArg: 9.276 ± 0.832
1.855AlaSer: 1.855 ± 1.224
1.855AlaThr: 1.855 ± 1.42
3.711AlaVal: 3.711 ± 2.448
0.0AlaTrp: 0.0 ± 0.0
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
3.711CysGlu: 3.711 ± 0.196
1.855CysPhe: 1.855 ± 1.224
1.855CysGly: 1.855 ± 1.224
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.855CysPro: 1.855 ± 1.224
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.855CysSer: 1.855 ± 1.224
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.855CysTyr: 1.855 ± 1.224
0.0CysXaa: 0.0 ± 0.0
Asp
5.566AspAla: 5.566 ± 1.616
0.0AspCys: 0.0 ± 0.0
3.711AspAsp: 3.711 ± 0.196
0.0AspGlu: 0.0 ± 0.0
7.421AspPhe: 7.421 ± 0.392
7.421AspGly: 7.421 ± 0.392
1.855AspHis: 1.855 ± 1.224
3.711AspIle: 3.711 ± 2.448
1.855AspLys: 1.855 ± 1.224
5.566AspLeu: 5.566 ± 1.028
0.0AspMet: 0.0 ± 0.0
3.711AspAsn: 3.711 ± 0.196
1.855AspPro: 1.855 ± 1.42
1.855AspGln: 1.855 ± 1.42
1.855AspArg: 1.855 ± 1.224
0.0AspSer: 0.0 ± 0.0
1.855AspThr: 1.855 ± 1.42
3.711AspVal: 3.711 ± 2.448
3.711AspTrp: 3.711 ± 0.196
3.711AspTyr: 3.711 ± 2.84
0.0AspXaa: 0.0 ± 0.0
Glu
1.855GluAla: 1.855 ± 1.224
0.0GluCys: 0.0 ± 0.0
7.421GluAsp: 7.421 ± 0.392
7.421GluGlu: 7.421 ± 2.252
9.276GluPhe: 9.276 ± 0.832
1.855GluGly: 1.855 ± 1.224
0.0GluHis: 0.0 ± 0.0
1.855GluIle: 1.855 ± 1.224
1.855GluLys: 1.855 ± 1.224
0.0GluLeu: 0.0 ± 0.0
5.566GluMet: 5.566 ± 1.028
1.855GluAsn: 1.855 ± 1.224
3.711GluPro: 3.711 ± 0.196
1.855GluGln: 1.855 ± 1.224
1.855GluArg: 1.855 ± 1.224
3.711GluSer: 3.711 ± 0.196
0.0GluThr: 0.0 ± 0.0
1.855GluVal: 1.855 ± 1.224
1.855GluTrp: 1.855 ± 1.42
1.855GluTyr: 1.855 ± 1.224
0.0GluXaa: 0.0 ± 0.0
Phe
1.855PheAla: 1.855 ± 1.224
1.855PheCys: 1.855 ± 1.224
0.0PheAsp: 0.0 ± 0.0
3.711PheGlu: 3.711 ± 0.196
1.855PhePhe: 1.855 ± 1.42
5.566PheGly: 5.566 ± 4.261
1.855PheHis: 1.855 ± 1.224
0.0PheIle: 0.0 ± 0.0
9.276PheLys: 9.276 ± 1.813
3.711PheLeu: 3.711 ± 0.196
0.0PheMet: 0.0 ± 0.0
1.855PheAsn: 1.855 ± 1.42
0.0PhePro: 0.0 ± 0.0
0.0PheGln: 0.0 ± 0.0
5.566PheArg: 5.566 ± 1.616
3.711PheSer: 3.711 ± 0.196
3.711PheThr: 3.711 ± 2.448
1.855PheVal: 1.855 ± 1.42
0.0PheTrp: 0.0 ± 0.0
3.711PheTyr: 3.711 ± 2.448
0.0PheXaa: 0.0 ± 0.0
Gly
3.711GlyAla: 3.711 ± 0.196
0.0GlyCys: 0.0 ± 0.0
1.855GlyAsp: 1.855 ± 1.224
5.566GlyGlu: 5.566 ± 3.672
5.566GlyPhe: 5.566 ± 1.616
1.855GlyGly: 1.855 ± 1.42
3.711GlyHis: 3.711 ± 2.84
1.855GlyIle: 1.855 ± 1.42
3.711GlyLys: 3.711 ± 2.448
5.566GlyLeu: 5.566 ± 1.028
0.0GlyMet: 0.0 ± 0.0
1.855GlyAsn: 1.855 ± 1.224
1.855GlyPro: 1.855 ± 1.224
3.711GlyGln: 3.711 ± 0.196
3.711GlyArg: 3.711 ± 2.448
7.421GlySer: 7.421 ± 2.252
9.276GlyThr: 9.276 ± 4.457
1.855GlyVal: 1.855 ± 1.224
1.855GlyTrp: 1.855 ± 1.224
1.855GlyTyr: 1.855 ± 1.224
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
1.855HisAsp: 1.855 ± 1.224
0.0HisGlu: 0.0 ± 0.0
3.711HisPhe: 3.711 ± 2.448
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
1.855HisLys: 1.855 ± 1.224
5.566HisLeu: 5.566 ± 1.616
0.0HisMet: 0.0 ± 0.0
1.855HisAsn: 1.855 ± 1.42
3.711HisPro: 3.711 ± 2.448
0.0HisGln: 0.0 ± 0.0
1.855HisArg: 1.855 ± 1.42
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
1.855HisTrp: 1.855 ± 1.224
1.855HisTyr: 1.855 ± 1.42
0.0HisXaa: 0.0 ± 0.0
Ile
1.855IleAla: 1.855 ± 1.224
1.855IleCys: 1.855 ± 1.224
0.0IleAsp: 0.0 ± 0.0
0.0IleGlu: 0.0 ± 0.0
0.0IlePhe: 0.0 ± 0.0
3.711IleGly: 3.711 ± 2.448
0.0IleHis: 0.0 ± 0.0
1.855IleIle: 1.855 ± 1.42
0.0IleLys: 0.0 ± 0.0
3.711IleLeu: 3.711 ± 0.196
3.711IleMet: 3.711 ± 0.196
7.421IleAsn: 7.421 ± 0.392
3.711IlePro: 3.711 ± 2.84
1.855IleGln: 1.855 ± 1.42
1.855IleArg: 1.855 ± 1.42
0.0IleSer: 0.0 ± 0.0
3.711IleThr: 3.711 ± 2.448
3.711IleVal: 3.711 ± 2.448
0.0IleTrp: 0.0 ± 0.0
3.711IleTyr: 3.711 ± 0.196
0.0IleXaa: 0.0 ± 0.0
Lys
3.711LysAla: 3.711 ± 2.448
1.855LysCys: 1.855 ± 1.224
0.0LysAsp: 0.0 ± 0.0
3.711LysGlu: 3.711 ± 2.448
1.855LysPhe: 1.855 ± 1.224
9.276LysGly: 9.276 ± 1.813
3.711LysHis: 3.711 ± 0.196
1.855LysIle: 1.855 ± 1.224
12.987LysLys: 12.987 ± 3.279
1.855LysLeu: 1.855 ± 1.224
3.711LysMet: 3.711 ± 0.835
0.0LysAsn: 0.0 ± 0.0
3.711LysPro: 3.711 ± 0.196
1.855LysGln: 1.855 ± 1.224
3.711LysArg: 3.711 ± 0.196
5.566LysSer: 5.566 ± 1.616
3.711LysThr: 3.711 ± 0.196
7.421LysVal: 7.421 ± 0.392
3.711LysTrp: 3.711 ± 0.196
1.855LysTyr: 1.855 ± 1.224
0.0LysXaa: 0.0 ± 0.0
Leu
16.698LeuAla: 16.698 ± 2.205
0.0LeuCys: 0.0 ± 0.0
5.566LeuAsp: 5.566 ± 4.261
1.855LeuGlu: 1.855 ± 1.42
3.711LeuPhe: 3.711 ± 0.196
0.0LeuGly: 0.0 ± 0.0
1.855LeuHis: 1.855 ± 1.224
0.0LeuIle: 0.0 ± 0.0
1.855LeuLys: 1.855 ± 1.224
3.711LeuLeu: 3.711 ± 2.448
3.711LeuMet: 3.711 ± 2.448
5.566LeuAsn: 5.566 ± 1.616
9.276LeuPro: 9.276 ± 0.832
3.711LeuGln: 3.711 ± 0.196
7.421LeuArg: 7.421 ± 2.252
5.566LeuSer: 5.566 ± 1.616
5.566LeuThr: 5.566 ± 1.616
0.0LeuVal: 0.0 ± 0.0
3.711LeuTrp: 3.711 ± 2.84
0.0LeuTyr: 0.0 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
1.855MetAla: 1.855 ± 1.224
0.0MetCys: 0.0 ± 0.0
5.566MetAsp: 5.566 ± 1.028
1.855MetGlu: 1.855 ± 1.224
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
1.855MetIle: 1.855 ± 1.224
5.566MetLys: 5.566 ± 1.028
1.855MetLeu: 1.855 ± 1.224
0.0MetMet: 0.0 ± 0.0
1.855MetAsn: 1.855 ± 1.42
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
1.855MetArg: 1.855 ± 1.42
0.0MetSer: 0.0 ± 0.0
0.0MetThr: 0.0 ± 0.0
1.855MetVal: 1.855 ± 1.224
1.855MetTrp: 1.855 ± 1.42
1.855MetTyr: 1.855 ± 1.224
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
0.0AsnCys: 0.0 ± 0.0
1.855AsnAsp: 1.855 ± 1.224
5.566AsnGlu: 5.566 ± 1.028
0.0AsnPhe: 0.0 ± 0.0
0.0AsnGly: 0.0 ± 0.0
1.855AsnHis: 1.855 ± 1.42
1.855AsnIle: 1.855 ± 1.42
1.855AsnLys: 1.855 ± 1.224
3.711AsnLeu: 3.711 ± 2.84
0.0AsnMet: 0.0 ± 0.0
3.711AsnAsn: 3.711 ± 0.196
1.855AsnPro: 1.855 ± 1.42
3.711AsnGln: 3.711 ± 2.84
5.566AsnArg: 5.566 ± 1.616
0.0AsnSer: 0.0 ± 0.0
1.855AsnThr: 1.855 ± 1.224
3.711AsnVal: 3.711 ± 2.84
3.711AsnTrp: 3.711 ± 2.84
3.711AsnTyr: 3.711 ± 2.448
0.0AsnXaa: 0.0 ± 0.0
Pro
3.711ProAla: 3.711 ± 0.196
0.0ProCys: 0.0 ± 0.0
3.711ProAsp: 3.711 ± 2.448
3.711ProGlu: 3.711 ± 0.196
3.711ProPhe: 3.711 ± 0.196
1.855ProGly: 1.855 ± 1.224
3.711ProHis: 3.711 ± 2.448
5.566ProIle: 5.566 ± 1.616
3.711ProLys: 3.711 ± 2.84
5.566ProLeu: 5.566 ± 4.261
0.0ProMet: 0.0 ± 0.0
1.855ProAsn: 1.855 ± 1.42
0.0ProPro: 0.0 ± 0.0
1.855ProGln: 1.855 ± 1.42
5.566ProArg: 5.566 ± 1.616
3.711ProSer: 3.711 ± 0.196
1.855ProThr: 1.855 ± 1.42
5.566ProVal: 5.566 ± 3.672
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
0.0GlnCys: 0.0 ± 0.0
1.855GlnAsp: 1.855 ± 1.42
0.0GlnGlu: 0.0 ± 0.0
0.0GlnPhe: 0.0 ± 0.0
5.566GlnGly: 5.566 ± 3.672
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
3.711GlnLys: 3.711 ± 0.196
3.711GlnLeu: 3.711 ± 2.84
3.711GlnMet: 3.711 ± 2.84
1.855GlnAsn: 1.855 ± 1.42
0.0GlnPro: 0.0 ± 0.0
0.0GlnGln: 0.0 ± 0.0
1.855GlnArg: 1.855 ± 1.224
0.0GlnSer: 0.0 ± 0.0
0.0GlnThr: 0.0 ± 0.0
5.566GlnVal: 5.566 ± 4.261
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
5.566ArgAla: 5.566 ± 3.672
0.0ArgCys: 0.0 ± 0.0
3.711ArgAsp: 3.711 ± 2.448
3.711ArgGlu: 3.711 ± 0.196
5.566ArgPhe: 5.566 ± 1.616
7.421ArgGly: 7.421 ± 2.252
0.0ArgHis: 0.0 ± 0.0
5.566ArgIle: 5.566 ± 1.616
3.711ArgLys: 3.711 ± 2.84
12.987ArgLeu: 12.987 ± 2.009
1.855ArgMet: 1.855 ± 1.224
0.0ArgAsn: 0.0 ± 0.0
5.566ArgPro: 5.566 ± 4.261
1.855ArgGln: 1.855 ± 1.42
25.974ArgArg: 25.974 ± 14.594
1.855ArgSer: 1.855 ± 1.224
1.855ArgThr: 1.855 ± 1.42
3.711ArgVal: 3.711 ± 2.84
3.711ArgTrp: 3.711 ± 0.196
3.711ArgTyr: 3.711 ± 0.196
0.0ArgXaa: 0.0 ± 0.0
Ser
1.855SerAla: 1.855 ± 1.224
0.0SerCys: 0.0 ± 0.0
5.566SerAsp: 5.566 ± 1.028
3.711SerGlu: 3.711 ± 2.448
1.855SerPhe: 1.855 ± 1.42
3.711SerGly: 3.711 ± 0.196
0.0SerHis: 0.0 ± 0.0
0.0SerIle: 0.0 ± 0.0
5.566SerLys: 5.566 ± 3.672
1.855SerLeu: 1.855 ± 1.42
0.0SerMet: 0.0 ± 0.0
3.711SerAsn: 3.711 ± 2.448
0.0SerPro: 0.0 ± 0.0
1.855SerGln: 1.855 ± 1.42
1.855SerArg: 1.855 ± 1.224
1.855SerSer: 1.855 ± 1.42
0.0SerThr: 0.0 ± 0.0
1.855SerVal: 1.855 ± 1.42
5.566SerTrp: 5.566 ± 1.616
1.855SerTyr: 1.855 ± 1.224
0.0SerXaa: 0.0 ± 0.0
Thr
3.711ThrAla: 3.711 ± 0.196
0.0ThrCys: 0.0 ± 0.0
5.566ThrAsp: 5.566 ± 4.261
1.855ThrGlu: 1.855 ± 1.224
1.855ThrPhe: 1.855 ± 1.42
3.711ThrGly: 3.711 ± 0.196
3.711ThrHis: 3.711 ± 0.196
5.566ThrIle: 5.566 ± 1.616
0.0ThrLys: 0.0 ± 0.0
1.855ThrLeu: 1.855 ± 1.224
0.0ThrMet: 0.0 ± 0.0
1.855ThrAsn: 1.855 ± 1.42
5.566ThrPro: 5.566 ± 1.616
0.0ThrGln: 0.0 ± 0.0
3.711ThrArg: 3.711 ± 2.84
3.711ThrSer: 3.711 ± 2.448
0.0ThrThr: 0.0 ± 0.0
0.0ThrVal: 0.0 ± 0.0
0.0ThrTrp: 0.0 ± 0.0
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
3.711ValAla: 3.711 ± 0.196
0.0ValCys: 0.0 ± 0.0
1.855ValAsp: 1.855 ± 1.224
3.711ValGlu: 3.711 ± 0.196
0.0ValPhe: 0.0 ± 0.0
1.855ValGly: 1.855 ± 1.224
0.0ValHis: 0.0 ± 0.0
7.421ValIle: 7.421 ± 4.896
9.276ValLys: 9.276 ± 0.832
1.855ValLeu: 1.855 ± 1.42
0.0ValMet: 0.0 ± 0.0
0.0ValAsn: 0.0 ± 0.0
5.566ValPro: 5.566 ± 1.028
1.855ValGln: 1.855 ± 1.224
5.566ValArg: 5.566 ± 1.028
0.0ValSer: 0.0 ± 0.0
5.566ValThr: 5.566 ± 4.261
3.711ValVal: 3.711 ± 2.448
0.0ValTrp: 0.0 ± 0.0
1.855ValTyr: 1.855 ± 1.42
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
1.855TrpCys: 1.855 ± 1.224
7.421TrpAsp: 7.421 ± 0.392
3.711TrpGlu: 3.711 ± 0.196
0.0TrpPhe: 0.0 ± 0.0
1.855TrpGly: 1.855 ± 1.42
0.0TrpHis: 0.0 ± 0.0
1.855TrpIle: 1.855 ± 1.42
1.855TrpLys: 1.855 ± 1.42
5.566TrpLeu: 5.566 ± 1.616
1.855TrpMet: 1.855 ± 1.224
0.0TrpAsn: 0.0 ± 0.0
1.855TrpPro: 1.855 ± 1.42
0.0TrpGln: 0.0 ± 0.0
3.711TrpArg: 3.711 ± 2.84
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
1.855TrpTrp: 1.855 ± 1.224
1.855TrpTyr: 1.855 ± 1.224
1.855TrpXaa: 1.855 ± 1.42
Tyr
0.0TyrAla: 0.0 ± 0.0
5.566TyrCys: 5.566 ± 1.028
0.0TyrAsp: 0.0 ± 0.0
0.0TyrGlu: 0.0 ± 0.0
0.0TyrPhe: 0.0 ± 0.0
5.566TyrGly: 5.566 ± 1.028
0.0TyrHis: 0.0 ± 0.0
0.0TyrIle: 0.0 ± 0.0
1.855TyrLys: 1.855 ± 1.224
1.855TyrLeu: 1.855 ± 1.224
0.0TyrMet: 0.0 ± 0.895
0.0TyrAsn: 0.0 ± 0.0
1.855TyrPro: 1.855 ± 1.224
1.855TyrGln: 1.855 ± 1.42
3.711TyrArg: 3.711 ± 2.84
1.855TyrSer: 1.855 ± 1.224
1.855TyrThr: 1.855 ± 1.224
3.711TyrVal: 3.711 ± 2.448
3.711TyrTrp: 3.711 ± 0.196
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
1.855XaaArg: 1.855 ± 1.42
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (540 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski