Amino acid dipepetide frequency for Raphanus sativus cryptic virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.554AlaAla: 8.554 ± 3.146
0.855AlaCys: 0.855 ± 0.72
5.133AlaAsp: 5.133 ± 1.643
4.277AlaGlu: 4.277 ± 0.613
6.843AlaPhe: 6.843 ± 0.807
4.277AlaGly: 4.277 ± 0.601
0.0AlaHis: 0.0 ± 0.0
7.699AlaIle: 7.699 ± 1.975
5.133AlaLys: 5.133 ± 1.643
4.277AlaLeu: 4.277 ± 1.81
1.711AlaMet: 1.711 ± 0.842
2.566AlaAsn: 2.566 ± 0.244
3.422AlaPro: 3.422 ± 1.244
2.566AlaGln: 2.566 ± 1.084
4.277AlaArg: 4.277 ± 0.613
8.554AlaSer: 8.554 ± 3.465
5.988AlaThr: 5.988 ± 3.471
4.277AlaVal: 4.277 ± 1.051
0.855AlaTrp: 0.855 ± 0.72
5.133AlaTyr: 5.133 ± 1.347
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.855CysGlu: 0.855 ± 0.648
0.855CysPhe: 0.855 ± 0.648
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.711CysLeu: 1.711 ± 1.296
0.855CysMet: 0.855 ± 0.72
0.0CysAsn: 0.0 ± 0.0
0.855CysPro: 0.855 ± 0.783
0.855CysGln: 0.855 ± 0.72
0.0CysArg: 0.0 ± 0.0
0.855CysSer: 0.855 ± 0.783
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.855CysTyr: 0.855 ± 0.783
0.0CysXaa: 0.0 ± 0.0
Asp
8.554AspAla: 8.554 ± 1.275
0.0AspCys: 0.0 ± 0.0
5.133AspAsp: 5.133 ± 0.89
4.277AspGlu: 4.277 ± 2.178
0.855AspPhe: 0.855 ± 0.648
5.988AspGly: 5.988 ± 1.159
3.422AspHis: 3.422 ± 0.403
1.711AspIle: 1.711 ± 0.892
1.711AspLys: 1.711 ± 0.653
5.133AspLeu: 5.133 ± 3.033
0.0AspMet: 0.0 ± 0.0
1.711AspAsn: 1.711 ± 0.622
3.422AspPro: 3.422 ± 0.403
3.422AspGln: 3.422 ± 1.884
3.422AspArg: 3.422 ± 0.876
2.566AspSer: 2.566 ± 0.244
3.422AspThr: 3.422 ± 2.066
5.133AspVal: 5.133 ± 0.489
0.855AspTrp: 0.855 ± 0.648
2.566AspTyr: 2.566 ± 0.244
0.0AspXaa: 0.0 ± 0.0
Glu
6.843GluAla: 6.843 ± 3.133
0.0GluCys: 0.0 ± 0.0
1.711GluAsp: 1.711 ± 0.622
1.711GluGlu: 1.711 ± 1.296
3.422GluPhe: 3.422 ± 1.566
7.699GluGly: 7.699 ± 1.356
0.855GluHis: 0.855 ± 0.648
6.843GluIle: 6.843 ± 0.696
2.566GluLys: 2.566 ± 1.084
1.711GluLeu: 1.711 ± 0.653
1.711GluMet: 1.711 ± 1.566
0.855GluAsn: 0.855 ± 0.72
2.566GluPro: 2.566 ± 1.084
0.855GluGln: 0.855 ± 0.72
2.566GluArg: 2.566 ± 1.419
4.277GluSer: 4.277 ± 1.823
0.855GluThr: 0.855 ± 0.783
5.133GluVal: 5.133 ± 0.82
0.855GluTrp: 0.855 ± 0.648
2.566GluTyr: 2.566 ± 1.084
0.0GluXaa: 0.0 ± 0.0
Phe
5.988PheAla: 5.988 ± 1.067
0.0PheCys: 0.0 ± 0.0
2.566PheAsp: 2.566 ± 1.943
1.711PheGlu: 1.711 ± 1.566
0.855PhePhe: 0.855 ± 0.648
0.855PheGly: 0.855 ± 0.648
1.711PheHis: 1.711 ± 0.622
4.277PheIle: 4.277 ± 1.051
4.277PheLys: 4.277 ± 2.178
5.988PheLeu: 5.988 ± 1.231
1.711PheMet: 1.711 ± 0.622
3.422PheAsn: 3.422 ± 1.784
2.566PhePro: 2.566 ± 1.084
0.855PheGln: 0.855 ± 0.648
4.277PheArg: 4.277 ± 0.601
3.422PheSer: 3.422 ± 0.958
2.566PheThr: 2.566 ± 1.084
2.566PheVal: 2.566 ± 1.943
0.0PheTrp: 0.0 ± 0.0
1.711PheTyr: 1.711 ± 0.622
0.0PheXaa: 0.0 ± 0.0
Gly
2.566GlyAla: 2.566 ± 1.419
0.0GlyCys: 0.0 ± 0.0
4.277GlyAsp: 4.277 ± 1.669
3.422GlyGlu: 3.422 ± 1.884
1.711GlyPhe: 1.711 ± 0.622
0.855GlyGly: 0.855 ± 0.72
1.711GlyHis: 1.711 ± 0.622
3.422GlyIle: 3.422 ± 1.307
0.855GlyLys: 0.855 ± 0.72
4.277GlyLeu: 4.277 ± 1.535
1.711GlyMet: 1.711 ± 0.892
4.277GlyAsn: 4.277 ± 2.362
1.711GlyPro: 1.711 ± 0.653
0.0GlyGln: 0.0 ± 0.0
5.133GlyArg: 5.133 ± 0.489
5.133GlySer: 5.133 ± 1.867
2.566GlyThr: 2.566 ± 1.0
2.566GlyVal: 2.566 ± 2.349
1.711GlyTrp: 1.711 ± 0.653
2.566GlyTyr: 2.566 ± 1.084
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
2.566HisAsp: 2.566 ± 0.244
2.566HisGlu: 2.566 ± 1.0
1.711HisPhe: 1.711 ± 0.892
0.855HisGly: 0.855 ± 0.648
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
1.711HisLys: 1.711 ± 0.653
2.566HisLeu: 2.566 ± 1.516
0.0HisMet: 0.0 ± 0.0
0.855HisAsn: 0.855 ± 0.648
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
0.855HisArg: 0.855 ± 0.72
1.711HisSer: 1.711 ± 0.622
0.855HisThr: 0.855 ± 0.648
1.711HisVal: 1.711 ± 1.296
0.0HisTrp: 0.0 ± 0.0
0.855HisTyr: 0.855 ± 0.648
0.0HisXaa: 0.0 ± 0.0
Ile
1.711IleAla: 1.711 ± 1.296
1.711IleCys: 1.711 ± 0.622
4.277IleAsp: 4.277 ± 1.137
3.422IleGlu: 3.422 ± 1.307
1.711IlePhe: 1.711 ± 1.296
4.277IleGly: 4.277 ± 1.669
0.855IleHis: 0.855 ± 0.648
1.711IleIle: 1.711 ± 0.653
0.855IleLys: 0.855 ± 0.783
2.566IleLeu: 2.566 ± 0.244
1.711IleMet: 1.711 ± 0.653
5.988IleAsn: 5.988 ± 1.231
4.277IlePro: 4.277 ± 0.613
3.422IleGln: 3.422 ± 0.876
5.133IleArg: 5.133 ± 0.82
4.277IleSer: 4.277 ± 1.535
1.711IleThr: 1.711 ± 0.653
2.566IleVal: 2.566 ± 1.212
0.855IleTrp: 0.855 ± 0.648
2.566IleTyr: 2.566 ± 1.084
0.0IleXaa: 0.0 ± 0.0
Lys
1.711LysAla: 1.711 ± 0.653
0.0LysCys: 0.0 ± 0.0
5.133LysAsp: 5.133 ± 2.3
0.0LysGlu: 0.0 ± 0.0
3.422LysPhe: 3.422 ± 0.403
1.711LysGly: 1.711 ± 0.653
0.0LysHis: 0.0 ± 0.0
3.422LysIle: 3.422 ± 1.662
0.855LysLys: 0.855 ± 0.648
4.277LysLeu: 4.277 ± 1.051
0.0LysMet: 0.0 ± 0.0
2.566LysAsn: 2.566 ± 1.419
2.566LysPro: 2.566 ± 2.349
3.422LysGln: 3.422 ± 1.566
1.711LysArg: 1.711 ± 0.892
5.988LysSer: 5.988 ± 1.345
5.988LysThr: 5.988 ± 1.159
5.133LysVal: 5.133 ± 1.867
0.855LysTrp: 0.855 ± 0.648
1.711LysTyr: 1.711 ± 0.622
0.0LysXaa: 0.0 ± 0.0
Leu
9.41LeuAla: 9.41 ± 1.937
0.855LeuCys: 0.855 ± 0.72
3.422LeuAsp: 3.422 ± 0.403
3.422LeuGlu: 3.422 ± 1.662
6.843LeuPhe: 6.843 ± 2.489
5.988LeuGly: 5.988 ± 3.294
1.711LeuHis: 1.711 ± 1.439
4.277LeuIle: 4.277 ± 2.278
6.843LeuLys: 6.843 ± 1.399
2.566LeuLeu: 2.566 ± 1.0
0.0LeuMet: 0.0 ± 0.0
0.855LeuAsn: 0.855 ± 0.783
5.988LeuPro: 5.988 ± 1.067
1.711LeuGln: 1.711 ± 1.296
10.265LeuArg: 10.265 ± 0.62
6.843LeuSer: 6.843 ± 2.489
4.277LeuThr: 4.277 ± 0.613
1.711LeuVal: 1.711 ± 0.622
0.0LeuTrp: 0.0 ± 0.0
3.422LeuTyr: 3.422 ± 1.307
0.0LeuXaa: 0.0 ± 0.0
Met
3.422MetAla: 3.422 ± 2.243
0.0MetCys: 0.0 ± 0.0
3.422MetAsp: 3.422 ± 0.958
0.0MetGlu: 0.0 ± 0.0
2.566MetPhe: 2.566 ± 1.212
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
1.711MetIle: 1.711 ± 0.622
0.0MetLys: 0.0 ± 0.0
2.566MetLeu: 2.566 ± 1.0
0.0MetMet: 0.0 ± 0.544
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
0.855MetArg: 0.855 ± 0.72
1.711MetSer: 1.711 ± 0.892
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
1.711MetTrp: 1.711 ± 0.622
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.422AsnAla: 3.422 ± 2.066
0.855AsnCys: 0.855 ± 0.783
1.711AsnAsp: 1.711 ± 0.892
3.422AsnGlu: 3.422 ± 0.876
3.422AsnPhe: 3.422 ± 0.876
1.711AsnGly: 1.711 ± 0.653
0.855AsnHis: 0.855 ± 0.783
1.711AsnIle: 1.711 ± 0.622
2.566AsnLys: 2.566 ± 2.349
4.277AsnLeu: 4.277 ± 1.585
0.855AsnMet: 0.855 ± 0.648
1.711AsnAsn: 1.711 ± 1.439
1.711AsnPro: 1.711 ± 0.622
2.566AsnGln: 2.566 ± 1.084
0.855AsnArg: 0.855 ± 0.783
0.855AsnSer: 0.855 ± 0.72
2.566AsnThr: 2.566 ± 1.084
5.133AsnVal: 5.133 ± 2.425
0.855AsnTrp: 0.855 ± 0.783
5.988AsnTyr: 5.988 ± 2.118
0.0AsnXaa: 0.0 ± 0.0
Pro
4.277ProAla: 4.277 ± 2.362
0.0ProCys: 0.0 ± 0.0
3.422ProAsp: 3.422 ± 0.958
5.988ProGlu: 5.988 ± 0.159
2.566ProPhe: 2.566 ± 0.244
0.855ProGly: 0.855 ± 0.72
1.711ProHis: 1.711 ± 0.622
2.566ProIle: 2.566 ± 1.084
2.566ProLys: 2.566 ± 0.244
5.133ProLeu: 5.133 ± 0.89
0.0ProMet: 0.0 ± 0.0
1.711ProAsn: 1.711 ± 0.622
1.711ProPro: 1.711 ± 1.439
0.0ProGln: 0.0 ± 0.0
2.566ProArg: 2.566 ± 1.516
5.133ProSer: 5.133 ± 0.82
6.843ProThr: 6.843 ± 0.643
2.566ProVal: 2.566 ± 1.516
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
0.855GlnAla: 0.855 ± 0.72
0.855GlnCys: 0.855 ± 0.648
1.711GlnAsp: 1.711 ± 0.892
1.711GlnGlu: 1.711 ± 0.622
0.0GlnPhe: 0.0 ± 0.0
0.855GlnGly: 0.855 ± 0.648
1.711GlnHis: 1.711 ± 1.296
3.422GlnIle: 3.422 ± 0.876
1.711GlnLys: 1.711 ± 1.296
4.277GlnLeu: 4.277 ± 2.178
0.0GlnMet: 0.0 ± 0.0
1.711GlnAsn: 1.711 ± 0.653
1.711GlnPro: 1.711 ± 0.892
0.0GlnGln: 0.0 ± 0.0
0.855GlnArg: 0.855 ± 0.648
0.855GlnSer: 0.855 ± 0.648
2.566GlnThr: 2.566 ± 0.244
2.566GlnVal: 2.566 ± 1.212
1.711GlnTrp: 1.711 ± 1.439
2.566GlnTyr: 2.566 ± 1.943
0.0GlnXaa: 0.0 ± 0.0
Arg
5.988ArgAla: 5.988 ± 1.159
0.855ArgCys: 0.855 ± 0.783
4.277ArgAsp: 4.277 ± 1.535
2.566ArgGlu: 2.566 ± 1.084
5.133ArgPhe: 5.133 ± 1.96
1.711ArgGly: 1.711 ± 1.439
0.0ArgHis: 0.0 ± 0.0
0.855ArgIle: 0.855 ± 0.648
1.711ArgLys: 1.711 ± 1.296
3.422ArgLeu: 3.422 ± 0.958
2.566ArgMet: 2.566 ± 1.257
5.988ArgAsn: 5.988 ± 0.159
1.711ArgPro: 1.711 ± 1.566
2.566ArgGln: 2.566 ± 0.244
3.422ArgArg: 3.422 ± 1.566
5.133ArgSer: 5.133 ± 1.263
5.988ArgThr: 5.988 ± 2.437
3.422ArgVal: 3.422 ± 0.876
0.0ArgTrp: 0.0 ± 0.0
2.566ArgTyr: 2.566 ± 1.516
0.0ArgXaa: 0.0 ± 0.0
Ser
5.133SerAla: 5.133 ± 1.347
0.855SerCys: 0.855 ± 0.648
2.566SerAsp: 2.566 ± 1.516
3.422SerGlu: 3.422 ± 2.0
3.422SerPhe: 3.422 ± 1.244
3.422SerGly: 3.422 ± 0.403
0.855SerHis: 0.855 ± 0.72
5.988SerIle: 5.988 ± 1.437
4.277SerLys: 4.277 ± 1.733
7.699SerLeu: 7.699 ± 2.594
0.855SerMet: 0.855 ± 0.783
5.133SerAsn: 5.133 ± 0.82
0.855SerPro: 0.855 ± 0.783
5.133SerGln: 5.133 ± 2.001
2.566SerArg: 2.566 ± 1.0
9.41SerSer: 9.41 ± 5.245
5.988SerThr: 5.988 ± 0.159
5.988SerVal: 5.988 ± 1.345
0.855SerTrp: 0.855 ± 0.783
4.277SerTyr: 4.277 ± 0.601
0.0SerXaa: 0.0 ± 0.0
Thr
7.699ThrAla: 7.699 ± 1.873
0.0ThrCys: 0.0 ± 0.0
5.988ThrAsp: 5.988 ± 1.067
1.711ThrGlu: 1.711 ± 0.622
0.855ThrPhe: 0.855 ± 0.648
0.0ThrGly: 0.0 ± 0.0
1.711ThrHis: 1.711 ± 0.653
3.422ThrIle: 3.422 ± 1.884
5.133ThrLys: 5.133 ± 1.263
8.554ThrLeu: 8.554 ± 2.102
2.566ThrMet: 2.566 ± 0.244
2.566ThrAsn: 2.566 ± 1.212
4.277ThrPro: 4.277 ± 0.613
2.566ThrGln: 2.566 ± 0.244
4.277ThrArg: 4.277 ± 1.585
2.566ThrSer: 2.566 ± 1.419
3.422ThrThr: 3.422 ± 1.884
5.988ThrVal: 5.988 ± 2.029
0.855ThrTrp: 0.855 ± 0.648
1.711ThrTyr: 1.711 ± 1.439
0.0ThrXaa: 0.0 ± 0.0
Val
3.422ValAla: 3.422 ± 0.876
0.855ValCys: 0.855 ± 0.648
2.566ValAsp: 2.566 ± 1.0
5.988ValGlu: 5.988 ± 1.345
3.422ValPhe: 3.422 ± 0.403
4.277ValGly: 4.277 ± 2.765
0.0ValHis: 0.0 ± 0.0
0.855ValIle: 0.855 ± 0.648
5.133ValLys: 5.133 ± 0.82
3.422ValLeu: 3.422 ± 0.958
0.855ValMet: 0.855 ± 0.558
3.422ValAsn: 3.422 ± 0.958
6.843ValPro: 6.843 ± 2.677
1.711ValGln: 1.711 ± 1.296
2.566ValArg: 2.566 ± 1.0
5.133ValSer: 5.133 ± 0.82
4.277ValThr: 4.277 ± 1.585
3.422ValVal: 3.422 ± 0.958
1.711ValTrp: 1.711 ± 1.296
5.133ValTyr: 5.133 ± 1.96
0.0ValXaa: 0.0 ± 0.0
Trp
0.855TrpAla: 0.855 ± 0.648
0.0TrpCys: 0.0 ± 0.0
1.711TrpAsp: 1.711 ± 0.653
0.855TrpGlu: 0.855 ± 0.648
0.0TrpPhe: 0.0 ± 0.0
0.855TrpGly: 0.855 ± 0.648
0.0TrpHis: 0.0 ± 0.0
0.855TrpIle: 0.855 ± 0.648
0.855TrpLys: 0.855 ± 0.783
0.855TrpLeu: 0.855 ± 0.783
0.0TrpMet: 0.0 ± 0.0
1.711TrpAsn: 1.711 ± 0.653
0.855TrpPro: 0.855 ± 0.72
0.0TrpGln: 0.0 ± 0.0
0.855TrpArg: 0.855 ± 0.648
2.566TrpSer: 2.566 ± 1.0
0.855TrpThr: 0.855 ± 0.72
0.0TrpVal: 0.0 ± 0.0
1.711TrpTrp: 1.711 ± 0.892
0.855TrpTyr: 0.855 ± 0.72
0.0TrpXaa: 0.0 ± 0.0
Tyr
5.988TyrAla: 5.988 ± 1.211
0.0TyrCys: 0.0 ± 0.0
1.711TyrAsp: 1.711 ± 1.439
4.277TyrGlu: 4.277 ± 1.137
1.711TyrPhe: 1.711 ± 0.653
4.277TyrGly: 4.277 ± 0.613
1.711TyrHis: 1.711 ± 0.622
0.855TyrIle: 0.855 ± 0.648
1.711TyrLys: 1.711 ± 0.653
5.133TyrLeu: 5.133 ± 0.82
0.855TyrMet: 0.855 ± 0.648
0.0TyrAsn: 0.0 ± 0.0
2.566TyrPro: 2.566 ± 0.244
0.0TyrGln: 0.0 ± 0.0
3.422TyrArg: 3.422 ± 1.662
1.711TyrSer: 1.711 ± 1.296
5.133TyrThr: 5.133 ± 1.643
5.133TyrVal: 5.133 ± 2.908
0.855TyrTrp: 0.855 ± 0.72
0.855TyrTyr: 0.855 ± 0.783
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1170 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski