Amino acid dipepetide frequency for Figwort mosaic virus (strain DxS) (FMV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.428AlaAla: 3.428 ± 2.091
0.428AlaCys: 0.428 ± 0.414
3.428AlaAsp: 3.428 ± 1.362
4.284AlaGlu: 4.284 ± 1.225
3.428AlaPhe: 3.428 ± 1.141
1.285AlaGly: 1.285 ± 0.578
0.857AlaHis: 0.857 ± 1.656
2.142AlaIle: 2.142 ± 1.117
3.428AlaLys: 3.428 ± 1.317
3.856AlaLeu: 3.856 ± 0.985
0.857AlaMet: 0.857 ± 0.635
2.142AlaAsn: 2.142 ± 0.56
0.428AlaPro: 0.428 ± 0.363
1.714AlaGln: 1.714 ± 0.814
2.571AlaArg: 2.571 ± 1.944
2.999AlaSer: 2.999 ± 1.32
3.428AlaThr: 3.428 ± 1.433
2.571AlaVal: 2.571 ± 1.165
0.0AlaTrp: 0.0 ± 0.0
2.571AlaTyr: 2.571 ± 0.735
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.428CysCys: 0.428 ± 0.438
0.857CysAsp: 0.857 ± 0.511
0.857CysGlu: 0.857 ± 0.721
0.428CysPhe: 0.428 ± 0.438
0.428CysGly: 0.428 ± 0.414
0.0CysHis: 0.0 ± 0.0
1.285CysIle: 1.285 ± 0.393
2.142CysLys: 2.142 ± 1.178
1.285CysLeu: 1.285 ± 0.686
0.428CysMet: 0.428 ± 0.363
1.285CysAsn: 1.285 ± 0.978
2.571CysPro: 2.571 ± 0.785
0.0CysGln: 0.0 ± 0.0
2.142CysArg: 2.142 ± 0.687
1.714CysSer: 1.714 ± 0.327
0.857CysThr: 0.857 ± 0.721
0.428CysVal: 0.428 ± 0.414
0.428CysTrp: 0.428 ± 0.438
0.428CysTyr: 0.428 ± 0.363
0.0CysXaa: 0.0 ± 0.0
Asp
1.285AspAla: 1.285 ± 0.393
1.285AspCys: 1.285 ± 0.638
2.142AspAsp: 2.142 ± 0.44
6.427AspGlu: 6.427 ± 2.218
3.428AspPhe: 3.428 ± 1.612
0.857AspGly: 0.857 ± 0.435
1.714AspHis: 1.714 ± 0.739
5.141AspIle: 5.141 ± 1.602
5.57AspLys: 5.57 ± 1.374
3.428AspLeu: 3.428 ± 1.07
0.0AspMet: 0.0 ± 0.0
2.142AspAsn: 2.142 ± 0.809
2.142AspPro: 2.142 ± 0.433
1.285AspGln: 1.285 ± 1.158
1.714AspArg: 1.714 ± 1.106
6.427AspSer: 6.427 ± 1.294
2.999AspThr: 2.999 ± 1.136
1.285AspVal: 1.285 ± 0.78
0.428AspTrp: 0.428 ± 0.414
1.714AspTyr: 1.714 ± 0.708
0.0AspXaa: 0.0 ± 0.0
Glu
1.285GluAla: 1.285 ± 0.645
1.714GluCys: 1.714 ± 0.979
3.428GluAsp: 3.428 ± 1.041
13.282GluGlu: 13.282 ± 5.061
1.714GluPhe: 1.714 ± 1.657
5.57GluGly: 5.57 ± 1.245
1.285GluHis: 1.285 ± 0.439
8.141GluIle: 8.141 ± 1.452
9.426GluLys: 9.426 ± 3.117
8.569GluLeu: 8.569 ± 1.613
2.142GluMet: 2.142 ± 1.14
5.141GluAsn: 5.141 ± 2.377
1.285GluPro: 1.285 ± 0.858
3.428GluGln: 3.428 ± 1.392
5.141GluArg: 5.141 ± 1.12
5.141GluSer: 5.141 ± 1.622
3.428GluThr: 3.428 ± 1.387
3.428GluVal: 3.428 ± 1.787
0.857GluTrp: 0.857 ± 0.828
0.857GluTyr: 0.857 ± 0.925
0.0GluXaa: 0.0 ± 0.0
Phe
2.571PheAla: 2.571 ± 0.527
2.142PheCys: 2.142 ± 0.919
2.142PheAsp: 2.142 ± 0.552
2.571PheGlu: 2.571 ± 0.527
0.428PhePhe: 0.428 ± 0.414
1.285PheGly: 1.285 ± 0.596
0.428PheHis: 0.428 ± 0.363
2.999PheIle: 2.999 ± 1.048
3.428PheLys: 3.428 ± 1.016
3.856PheLeu: 3.856 ± 2.374
0.857PheMet: 0.857 ± 0.495
2.142PheAsn: 2.142 ± 0.727
2.142PhePro: 2.142 ± 0.552
2.999PheGln: 2.999 ± 0.708
3.428PheArg: 3.428 ± 1.503
5.141PheSer: 5.141 ± 0.98
3.856PheThr: 3.856 ± 0.887
0.428PheVal: 0.428 ± 0.414
0.857PheTrp: 0.857 ± 0.726
2.142PheTyr: 2.142 ± 1.215
0.0PheXaa: 0.0 ± 0.0
Gly
2.142GlyAla: 2.142 ± 0.843
0.428GlyCys: 0.428 ± 0.438
2.571GlyAsp: 2.571 ± 1.165
2.571GlyGlu: 2.571 ± 1.006
1.714GlyPhe: 1.714 ± 0.622
0.428GlyGly: 0.428 ± 0.363
1.285GlyHis: 1.285 ± 0.638
3.856GlyIle: 3.856 ± 0.735
5.998GlyLys: 5.998 ± 0.813
4.284GlyLeu: 4.284 ± 1.863
0.857GlyMet: 0.857 ± 0.591
2.999GlyAsn: 2.999 ± 1.571
0.428GlyPro: 0.428 ± 0.414
1.714GlyGln: 1.714 ± 1.041
1.285GlyArg: 1.285 ± 0.765
2.999GlySer: 2.999 ± 1.213
1.285GlyThr: 1.285 ± 0.638
2.142GlyVal: 2.142 ± 1.351
0.0GlyTrp: 0.0 ± 0.0
1.285GlyTyr: 1.285 ± 0.439
0.0GlyXaa: 0.0 ± 0.0
His
0.428HisAla: 0.428 ± 0.414
1.285HisCys: 1.285 ± 0.844
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
1.714HisPhe: 1.714 ± 0.693
0.857HisGly: 0.857 ± 0.916
0.428HisHis: 0.428 ± 0.414
1.285HisIle: 1.285 ± 0.71
1.285HisLys: 1.285 ± 0.393
4.284HisLeu: 4.284 ± 2.053
0.857HisMet: 0.857 ± 0.726
0.428HisAsn: 0.428 ± 0.363
0.0HisPro: 0.0 ± 0.0
1.714HisGln: 1.714 ± 1.149
0.428HisArg: 0.428 ± 0.438
1.285HisSer: 1.285 ± 0.903
0.428HisThr: 0.428 ± 0.414
0.857HisVal: 0.857 ± 0.609
0.0HisTrp: 0.0 ± 0.0
0.857HisTyr: 0.857 ± 0.409
0.0HisXaa: 0.0 ± 0.0
Ile
4.284IleAla: 4.284 ± 0.777
1.714IleCys: 1.714 ± 0.708
5.57IleAsp: 5.57 ± 2.392
7.284IleGlu: 7.284 ± 1.768
3.428IlePhe: 3.428 ± 1.155
3.856IleGly: 3.856 ± 0.752
3.428IleHis: 3.428 ± 1.404
5.57IleIle: 5.57 ± 2.087
7.712IleLys: 7.712 ± 1.452
5.141IleLeu: 5.141 ± 1.591
0.857IleMet: 0.857 ± 0.791
3.428IleAsn: 3.428 ± 1.32
4.713IlePro: 4.713 ± 1.227
4.284IleGln: 4.284 ± 0.61
2.142IleArg: 2.142 ± 0.898
5.998IleSer: 5.998 ± 1.982
2.999IleThr: 2.999 ± 0.942
2.999IleVal: 2.999 ± 1.043
0.428IleTrp: 0.428 ± 0.414
1.285IleTyr: 1.285 ± 0.494
0.0IleXaa: 0.0 ± 0.0
Lys
7.284LysAla: 7.284 ± 1.457
0.857LysCys: 0.857 ± 0.875
8.569LysAsp: 8.569 ± 2.267
7.284LysGlu: 7.284 ± 2.415
5.57LysPhe: 5.57 ± 1.043
1.714LysGly: 1.714 ± 0.529
0.857LysHis: 0.857 ± 0.435
8.997LysIle: 8.997 ± 1.875
15.853LysLys: 15.853 ± 5.169
7.712LysLeu: 7.712 ± 1.082
2.142LysMet: 2.142 ± 0.859
7.284LysAsn: 7.284 ± 2.543
3.428LysPro: 3.428 ± 0.783
6.855LysGln: 6.855 ± 1.971
4.713LysArg: 4.713 ± 1.83
8.997LysSer: 8.997 ± 2.281
4.713LysThr: 4.713 ± 1.917
8.569LysVal: 8.569 ± 1.558
1.714LysTrp: 1.714 ± 0.979
3.428LysTyr: 3.428 ± 1.54
0.0LysXaa: 0.0 ± 0.0
Leu
3.428LeuAla: 3.428 ± 0.752
1.285LeuCys: 1.285 ± 0.393
6.855LeuAsp: 6.855 ± 2.406
7.284LeuGlu: 7.284 ± 0.884
0.857LeuPhe: 0.857 ± 0.726
6.427LeuGly: 6.427 ± 0.905
0.857LeuHis: 0.857 ± 0.831
8.569LeuIle: 8.569 ± 2.407
10.711LeuLys: 10.711 ± 2.415
5.141LeuLeu: 5.141 ± 1.807
1.714LeuMet: 1.714 ± 1.023
4.713LeuAsn: 4.713 ± 1.097
1.714LeuPro: 1.714 ± 0.693
4.284LeuGln: 4.284 ± 2.447
3.856LeuArg: 3.856 ± 1.479
5.141LeuSer: 5.141 ± 1.729
6.855LeuThr: 6.855 ± 1.465
4.713LeuVal: 4.713 ± 1.612
1.285LeuTrp: 1.285 ± 0.765
2.571LeuTyr: 2.571 ± 0.792
0.0LeuXaa: 0.0 ± 0.0
Met
1.285MetAla: 1.285 ± 0.794
0.428MetCys: 0.428 ± 0.414
0.857MetAsp: 0.857 ± 0.828
1.714MetGlu: 1.714 ± 1.297
0.857MetPhe: 0.857 ± 0.511
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.857MetIle: 0.857 ± 0.511
1.714MetLys: 1.714 ± 1.017
1.285MetLeu: 1.285 ± 1.188
0.0MetMet: 0.0 ± 0.0
0.428MetAsn: 0.428 ± 0.438
0.857MetPro: 0.857 ± 0.925
1.285MetGln: 1.285 ± 0.686
0.428MetArg: 0.428 ± 0.438
2.571MetSer: 2.571 ± 0.927
0.857MetThr: 0.857 ± 0.435
1.714MetVal: 1.714 ± 1.008
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.571AsnAla: 2.571 ± 1.344
0.0AsnCys: 0.0 ± 0.0
0.857AsnAsp: 0.857 ± 0.435
5.998AsnGlu: 5.998 ± 1.761
3.428AsnPhe: 3.428 ± 0.652
2.571AsnGly: 2.571 ± 1.027
1.285AsnHis: 1.285 ± 0.844
3.856AsnIle: 3.856 ± 0.89
4.713AsnLys: 4.713 ± 1.466
7.284AsnLeu: 7.284 ± 1.646
1.285AsnMet: 1.285 ± 0.924
1.285AsnAsn: 1.285 ± 0.565
5.141AsnPro: 5.141 ± 1.372
1.714AsnGln: 1.714 ± 0.735
1.285AsnArg: 1.285 ± 0.715
4.284AsnSer: 4.284 ± 1.054
0.0AsnThr: 0.0 ± 0.0
1.714AsnVal: 1.714 ± 0.732
2.142AsnTrp: 2.142 ± 1.052
1.285AsnTyr: 1.285 ± 0.686
0.0AsnXaa: 0.0 ± 0.0
Pro
0.857ProAla: 0.857 ± 0.435
0.0ProCys: 0.0 ± 0.0
2.142ProAsp: 2.142 ± 1.117
3.428ProGlu: 3.428 ± 1.041
2.142ProPhe: 2.142 ± 0.727
1.285ProGly: 1.285 ± 0.829
0.428ProHis: 0.428 ± 0.541
1.714ProIle: 1.714 ± 0.622
2.999ProLys: 2.999 ± 1.068
4.284ProLeu: 4.284 ± 1.088
0.428ProMet: 0.428 ± 0.363
3.856ProAsn: 3.856 ± 1.136
0.857ProPro: 0.857 ± 0.721
1.714ProGln: 1.714 ± 0.954
0.857ProArg: 0.857 ± 0.848
3.856ProSer: 3.856 ± 0.998
1.285ProThr: 1.285 ± 1.188
2.999ProVal: 2.999 ± 1.88
0.0ProTrp: 0.0 ± 0.0
0.857ProTyr: 0.857 ± 0.828
0.0ProXaa: 0.0 ± 0.0
Gln
3.856GlnAla: 3.856 ± 1.526
0.428GlnCys: 0.428 ± 0.6
1.714GlnAsp: 1.714 ± 0.327
6.427GlnGlu: 6.427 ± 0.819
1.714GlnPhe: 1.714 ± 0.801
2.142GlnGly: 2.142 ± 0.433
0.857GlnHis: 0.857 ± 0.831
4.713GlnIle: 4.713 ± 0.651
3.856GlnLys: 3.856 ± 1.721
2.999GlnLeu: 2.999 ± 1.619
0.0GlnMet: 0.0 ± 0.0
2.571GlnAsn: 2.571 ± 0.85
0.428GlnPro: 0.428 ± 0.414
2.142GlnGln: 2.142 ± 0.995
1.285GlnArg: 1.285 ± 0.638
3.856GlnSer: 3.856 ± 1.459
2.571GlnThr: 2.571 ± 1.474
2.999GlnVal: 2.999 ± 1.955
1.285GlnTrp: 1.285 ± 1.089
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
1.714ArgAla: 1.714 ± 1.155
0.428ArgCys: 0.428 ± 0.438
1.285ArgAsp: 1.285 ± 0.596
2.142ArgGlu: 2.142 ± 0.881
1.714ArgPhe: 1.714 ± 0.739
2.142ArgGly: 2.142 ± 0.74
0.428ArgHis: 0.428 ± 0.363
5.141ArgIle: 5.141 ± 1.169
5.998ArgLys: 5.998 ± 2.556
2.999ArgLeu: 2.999 ± 1.141
0.857ArgMet: 0.857 ± 0.409
2.142ArgAsn: 2.142 ± 1.186
0.428ArgPro: 0.428 ± 0.414
1.714ArgGln: 1.714 ± 1.224
1.714ArgArg: 1.714 ± 0.693
2.999ArgSer: 2.999 ± 1.925
1.714ArgThr: 1.714 ± 0.708
0.857ArgVal: 0.857 ± 0.435
0.857ArgTrp: 0.857 ± 0.409
2.142ArgTyr: 2.142 ± 0.818
0.0ArgXaa: 0.0 ± 0.0
Ser
2.571SerAla: 2.571 ± 1.059
0.428SerCys: 0.428 ± 0.414
4.284SerAsp: 4.284 ± 1.02
3.428SerGlu: 3.428 ± 1.57
6.855SerPhe: 6.855 ± 2.861
3.428SerGly: 3.428 ± 1.571
2.142SerHis: 2.142 ± 1.032
5.57SerIle: 5.57 ± 1.845
11.568SerLys: 11.568 ± 1.706
9.426SerLeu: 9.426 ± 2.778
1.285SerMet: 1.285 ± 0.821
2.999SerAsn: 2.999 ± 1.147
3.856SerPro: 3.856 ± 1.228
2.571SerGln: 2.571 ± 0.852
1.285SerArg: 1.285 ± 0.494
11.14SerSer: 11.14 ± 2.521
5.57SerThr: 5.57 ± 2.338
3.428SerVal: 3.428 ± 1.741
0.428SerTrp: 0.428 ± 0.414
1.714SerTyr: 1.714 ± 1.268
0.0SerXaa: 0.0 ± 0.0
Thr
2.999ThrAla: 2.999 ± 1.065
1.285ThrCys: 1.285 ± 0.393
1.285ThrAsp: 1.285 ± 0.638
4.713ThrGlu: 4.713 ± 1.777
0.428ThrPhe: 0.428 ± 0.414
3.856ThrGly: 3.856 ± 1.379
0.428ThrHis: 0.428 ± 0.363
2.571ThrIle: 2.571 ± 1.503
8.141ThrLys: 8.141 ± 2.146
3.428ThrLeu: 3.428 ± 1.598
0.857ThrMet: 0.857 ± 0.511
2.999ThrAsn: 2.999 ± 0.905
2.571ThrPro: 2.571 ± 1.192
0.857ThrGln: 0.857 ± 0.641
1.714ThrArg: 1.714 ± 0.327
3.856ThrSer: 3.856 ± 1.002
1.714ThrThr: 1.714 ± 1.297
2.142ThrVal: 2.142 ± 0.913
0.857ThrTrp: 0.857 ± 0.409
2.999ThrTyr: 2.999 ± 0.749
0.0ThrXaa: 0.0 ± 0.0
Val
1.285ValAla: 1.285 ± 1.243
1.285ValCys: 1.285 ± 0.686
1.285ValAsp: 1.285 ± 0.78
2.571ValGlu: 2.571 ± 1.372
1.714ValPhe: 1.714 ± 0.749
0.857ValGly: 0.857 ± 0.63
0.857ValHis: 0.857 ± 0.541
2.142ValIle: 2.142 ± 0.751
8.569ValLys: 8.569 ± 1.935
5.141ValLeu: 5.141 ± 1.766
0.857ValMet: 0.857 ± 0.511
2.999ValAsn: 2.999 ± 1.902
0.857ValPro: 0.857 ± 0.641
2.999ValGln: 2.999 ± 2.03
2.999ValArg: 2.999 ± 1.001
3.428ValSer: 3.428 ± 0.939
2.142ValThr: 2.142 ± 1.167
1.714ValVal: 1.714 ± 0.954
0.0ValTrp: 0.0 ± 0.0
2.999ValTyr: 2.999 ± 1.151
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.428TrpCys: 0.428 ± 0.414
1.285TrpAsp: 1.285 ± 1.313
1.714TrpGlu: 1.714 ± 0.87
1.714TrpPhe: 1.714 ± 0.696
0.428TrpGly: 0.428 ± 0.363
0.0TrpHis: 0.0 ± 0.0
0.857TrpIle: 0.857 ± 0.875
0.857TrpLys: 0.857 ± 0.409
0.428TrpLeu: 0.428 ± 0.541
0.428TrpMet: 0.428 ± 0.363
0.857TrpAsn: 0.857 ± 0.641
0.428TrpPro: 0.428 ± 0.6
0.857TrpGln: 0.857 ± 0.726
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
0.857TrpThr: 0.857 ± 0.508
0.428TrpVal: 0.428 ± 0.414
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.571TyrAla: 2.571 ± 0.95
1.714TyrCys: 1.714 ± 0.814
0.857TyrAsp: 0.857 ± 0.52
1.285TyrGlu: 1.285 ± 0.858
2.571TyrPhe: 2.571 ± 1.192
0.857TyrGly: 0.857 ± 0.508
0.857TyrHis: 0.857 ± 0.435
1.714TyrIle: 1.714 ± 1.221
2.571TyrLys: 2.571 ± 0.668
3.428TyrLeu: 3.428 ± 0.655
0.0TyrMet: 0.0 ± 0.0
1.285TyrAsn: 1.285 ± 0.686
1.714TyrPro: 1.714 ± 0.724
1.714TyrGln: 1.714 ± 1.008
0.428TyrArg: 0.428 ± 0.414
2.142TyrSer: 2.142 ± 0.898
2.142TyrThr: 2.142 ± 1.409
1.285TyrVal: 1.285 ± 1.089
0.0TyrTrp: 0.0 ± 0.0
0.857TyrTyr: 0.857 ± 0.658
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (2335 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski