Amino acid dipepetide frequency for Floricoccus tropicus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.424AlaAla: 4.424 ± 0.124
0.393AlaCys: 0.393 ± 0.023
3.721AlaAsp: 3.721 ± 0.077
4.19AlaGlu: 4.19 ± 0.1
2.851AlaPhe: 2.851 ± 0.082
4.694AlaGly: 4.694 ± 0.105
1.016AlaHis: 1.016 ± 0.044
5.535AlaIle: 5.535 ± 0.095
4.953AlaLys: 4.953 ± 0.101
6.311AlaLeu: 6.311 ± 0.098
1.77AlaMet: 1.77 ± 0.059
3.188AlaAsn: 3.188 ± 0.075
1.87AlaPro: 1.87 ± 0.069
2.355AlaGln: 2.355 ± 0.058
2.493AlaArg: 2.493 ± 0.062
4.185AlaSer: 4.185 ± 0.098
3.689AlaThr: 3.689 ± 0.09
4.567AlaVal: 4.567 ± 0.075
0.558AlaTrp: 0.558 ± 0.03
2.342AlaTyr: 2.342 ± 0.059
0.0AlaXaa: 0.0 ± 0.0
Cys
0.294CysAla: 0.294 ± 0.024
0.046CysCys: 0.046 ± 0.01
0.288CysAsp: 0.288 ± 0.022
0.245CysGlu: 0.245 ± 0.02
0.227CysPhe: 0.227 ± 0.019
0.488CysGly: 0.488 ± 0.03
0.114CysHis: 0.114 ± 0.016
0.38CysIle: 0.38 ± 0.028
0.296CysLys: 0.296 ± 0.021
0.466CysLeu: 0.466 ± 0.031
0.111CysMet: 0.111 ± 0.012
0.221CysAsn: 0.221 ± 0.019
0.216CysPro: 0.216 ± 0.02
0.192CysGln: 0.192 ± 0.018
0.161CysArg: 0.161 ± 0.018
0.375CysSer: 0.375 ± 0.023
0.231CysThr: 0.231 ± 0.023
0.251CysVal: 0.251 ± 0.024
0.037CysTrp: 0.037 ± 0.008
0.188CysTyr: 0.188 ± 0.017
0.0CysXaa: 0.0 ± 0.0
Asp
3.732AspAla: 3.732 ± 0.092
0.274AspCys: 0.274 ± 0.021
3.784AspAsp: 3.784 ± 0.101
5.327AspGlu: 5.327 ± 0.1
3.589AspPhe: 3.589 ± 0.074
4.254AspGly: 4.254 ± 0.096
0.774AspHis: 0.774 ± 0.038
5.254AspIle: 5.254 ± 0.091
5.406AspLys: 5.406 ± 0.117
5.826AspLeu: 5.826 ± 0.101
1.573AspMet: 1.573 ± 0.043
3.292AspAsn: 3.292 ± 0.072
1.517AspPro: 1.517 ± 0.061
1.678AspGln: 1.678 ± 0.049
1.948AspArg: 1.948 ± 0.065
3.606AspSer: 3.606 ± 0.087
2.899AspThr: 2.899 ± 0.074
3.996AspVal: 3.996 ± 0.077
0.588AspTrp: 0.588 ± 0.034
3.093AspTyr: 3.093 ± 0.078
0.0AspXaa: 0.0 ± 0.0
Glu
4.279GluAla: 4.279 ± 0.092
0.251GluCys: 0.251 ± 0.022
4.382GluAsp: 4.382 ± 0.102
6.314GluGlu: 6.314 ± 0.127
3.191GluPhe: 3.191 ± 0.076
3.583GluGly: 3.583 ± 0.075
0.921GluHis: 0.921 ± 0.043
6.529GluIle: 6.529 ± 0.113
6.928GluLys: 6.928 ± 0.123
6.874GluLeu: 6.874 ± 0.127
1.835GluMet: 1.835 ± 0.049
5.341GluAsn: 5.341 ± 0.104
1.487GluPro: 1.487 ± 0.048
2.33GluGln: 2.33 ± 0.062
2.837GluArg: 2.837 ± 0.081
3.7GluSer: 3.7 ± 0.089
3.172GluThr: 3.172 ± 0.073
4.913GluVal: 4.913 ± 0.102
0.558GluTrp: 0.558 ± 0.029
2.632GluTyr: 2.632 ± 0.077
0.0GluXaa: 0.0 ± 0.0
Phe
3.148PheAla: 3.148 ± 0.076
0.289PheCys: 0.289 ± 0.021
3.4PheAsp: 3.4 ± 0.081
3.257PheGlu: 3.257 ± 0.072
2.285PhePhe: 2.285 ± 0.082
3.263PheGly: 3.263 ± 0.078
0.639PheHis: 0.639 ± 0.028
4.091PheIle: 4.091 ± 0.105
3.055PheLys: 3.055 ± 0.072
4.491PheLeu: 4.491 ± 0.096
1.174PheMet: 1.174 ± 0.043
2.516PheAsn: 2.516 ± 0.063
1.547PhePro: 1.547 ± 0.047
1.358PheGln: 1.358 ± 0.051
1.348PheArg: 1.348 ± 0.054
3.517PheSer: 3.517 ± 0.091
2.619PheThr: 2.619 ± 0.071
3.236PheVal: 3.236 ± 0.076
0.455PheTrp: 0.455 ± 0.027
1.959PheTyr: 1.959 ± 0.057
0.0PheXaa: 0.0 ± 0.0
Gly
4.343GlyAla: 4.343 ± 0.107
0.374GlyCys: 0.374 ± 0.028
3.431GlyAsp: 3.431 ± 0.082
3.584GlyGlu: 3.584 ± 0.073
3.253GlyPhe: 3.253 ± 0.076
4.19GlyGly: 4.19 ± 0.114
1.134GlyHis: 1.134 ± 0.048
5.779GlyIle: 5.779 ± 0.105
4.988GlyLys: 4.988 ± 0.082
5.998GlyLeu: 5.998 ± 0.105
1.814GlyMet: 1.814 ± 0.054
3.09GlyAsn: 3.09 ± 0.07
1.399GlyPro: 1.399 ± 0.051
2.611GlyGln: 2.611 ± 0.076
2.434GlyArg: 2.434 ± 0.064
3.815GlySer: 3.815 ± 0.077
3.613GlyThr: 3.613 ± 0.085
4.599GlyVal: 4.599 ± 0.098
0.579GlyTrp: 0.579 ± 0.033
2.605GlyTyr: 2.605 ± 0.067
0.0GlyXaa: 0.0 ± 0.0
His
0.908HisAla: 0.908 ± 0.043
0.089HisCys: 0.089 ± 0.012
0.978HisAsp: 0.978 ± 0.039
1.064HisGlu: 1.064 ± 0.042
0.762HisPhe: 0.762 ± 0.036
1.111HisGly: 1.111 ± 0.047
0.35HisHis: 0.35 ± 0.024
1.166HisIle: 1.166 ± 0.044
0.867HisLys: 0.867 ± 0.035
1.409HisLeu: 1.409 ± 0.048
0.37HisMet: 0.37 ± 0.025
0.709HisAsn: 0.709 ± 0.034
0.704HisPro: 0.704 ± 0.036
0.493HisGln: 0.493 ± 0.025
0.612HisArg: 0.612 ± 0.031
0.898HisSer: 0.898 ± 0.041
0.738HisThr: 0.738 ± 0.033
0.894HisVal: 0.894 ± 0.04
0.135HisTrp: 0.135 ± 0.014
0.598HisTyr: 0.598 ± 0.032
0.0HisXaa: 0.0 ± 0.0
Ile
5.957IleAla: 5.957 ± 0.113
0.544IleCys: 0.544 ± 0.034
5.456IleAsp: 5.456 ± 0.099
6.167IleGlu: 6.167 ± 0.096
4.481IlePhe: 4.481 ± 0.112
5.279IleGly: 5.279 ± 0.099
1.188IleHis: 1.188 ± 0.046
7.418IleIle: 7.418 ± 0.157
6.031IleLys: 6.031 ± 0.099
8.339IleLeu: 8.339 ± 0.154
2.066IleMet: 2.066 ± 0.063
4.688IleAsn: 4.688 ± 0.088
3.153IlePro: 3.153 ± 0.067
2.32IleGln: 2.32 ± 0.058
2.706IleArg: 2.706 ± 0.063
6.222IleSer: 6.222 ± 0.132
4.212IleThr: 4.212 ± 0.089
5.573IleVal: 5.573 ± 0.124
0.631IleTrp: 0.631 ± 0.031
3.225IleTyr: 3.225 ± 0.077
0.0IleXaa: 0.0 ± 0.0
Lys
4.5LysAla: 4.5 ± 0.109
0.207LysCys: 0.207 ± 0.021
5.135LysAsp: 5.135 ± 0.101
6.853LysGlu: 6.853 ± 0.121
3.012LysPhe: 3.012 ± 0.07
3.664LysGly: 3.664 ± 0.081
0.978LysHis: 0.978 ± 0.043
6.995LysIle: 6.995 ± 0.121
7.017LysLys: 7.017 ± 0.143
6.764LysLeu: 6.764 ± 0.109
2.365LysMet: 2.365 ± 0.063
5.448LysAsn: 5.448 ± 0.108
1.997LysPro: 1.997 ± 0.059
2.225LysGln: 2.225 ± 0.067
2.681LysArg: 2.681 ± 0.072
4.683LysSer: 4.683 ± 0.095
3.937LysThr: 3.937 ± 0.085
5.038LysVal: 5.038 ± 0.093
0.588LysTrp: 0.588 ± 0.029
3.311LysTyr: 3.311 ± 0.078
0.0LysXaa: 0.0 ± 0.0
Leu
7.241LeuAla: 7.241 ± 0.112
0.401LeuCys: 0.401 ± 0.027
5.938LeuAsp: 5.938 ± 0.097
6.588LeuGlu: 6.588 ± 0.136
4.304LeuPhe: 4.304 ± 0.1
5.992LeuGly: 5.992 ± 0.109
1.256LeuHis: 1.256 ± 0.046
7.75LeuIle: 7.75 ± 0.142
6.79LeuLys: 6.79 ± 0.106
8.927LeuLeu: 8.927 ± 0.13
2.339LeuMet: 2.339 ± 0.065
4.882LeuAsn: 4.882 ± 0.094
3.481LeuPro: 3.481 ± 0.081
2.765LeuGln: 2.765 ± 0.072
3.142LeuArg: 3.142 ± 0.077
7.351LeuSer: 7.351 ± 0.119
5.416LeuThr: 5.416 ± 0.099
6.357LeuVal: 6.357 ± 0.112
0.663LeuTrp: 0.663 ± 0.037
3.026LeuTyr: 3.026 ± 0.071
0.0LeuXaa: 0.0 ± 0.0
Met
1.822MetAla: 1.822 ± 0.059
0.097MetCys: 0.097 ± 0.012
1.52MetAsp: 1.52 ± 0.048
1.587MetGlu: 1.587 ± 0.049
1.029MetPhe: 1.029 ± 0.039
1.636MetGly: 1.636 ± 0.049
0.331MetHis: 0.331 ± 0.022
2.14MetIle: 2.14 ± 0.056
2.283MetLys: 2.283 ± 0.061
2.204MetLeu: 2.204 ± 0.064
0.709MetMet: 0.709 ± 0.04
1.624MetAsn: 1.624 ± 0.044
0.867MetPro: 0.867 ± 0.041
0.84MetGln: 0.84 ± 0.035
0.895MetArg: 0.895 ± 0.036
1.749MetSer: 1.749 ± 0.057
1.771MetThr: 1.771 ± 0.055
1.593MetVal: 1.593 ± 0.056
0.156MetTrp: 0.156 ± 0.017
0.724MetTyr: 0.724 ± 0.032
0.0MetXaa: 0.0 ± 0.0
Asn
2.991AsnAla: 2.991 ± 0.08
0.289AsnCys: 0.289 ± 0.023
3.268AsnAsp: 3.268 ± 0.073
3.673AsnGlu: 3.673 ± 0.074
2.945AsnPhe: 2.945 ± 0.069
3.656AsnGly: 3.656 ± 0.077
0.995AsnHis: 0.995 ± 0.039
4.968AsnIle: 4.968 ± 0.101
4.368AsnLys: 4.368 ± 0.087
5.688AsnLeu: 5.688 ± 0.091
1.396AsnMet: 1.396 ± 0.043
3.416AsnAsn: 3.416 ± 0.094
2.333AsnPro: 2.333 ± 0.062
2.045AsnGln: 2.045 ± 0.062
1.9AsnArg: 1.9 ± 0.06
3.532AsnSer: 3.532 ± 0.081
2.563AsnThr: 2.563 ± 0.07
3.298AsnVal: 3.298 ± 0.072
0.545AsnTrp: 0.545 ± 0.03
2.42AsnTyr: 2.42 ± 0.07
0.0AsnXaa: 0.0 ± 0.0
Pro
1.964ProAla: 1.964 ± 0.064
0.132ProCys: 0.132 ± 0.016
2.059ProAsp: 2.059 ± 0.062
2.608ProGlu: 2.608 ± 0.064
1.604ProPhe: 1.604 ± 0.053
1.833ProGly: 1.833 ± 0.057
0.509ProHis: 0.509 ± 0.032
2.597ProIle: 2.597 ± 0.073
2.191ProLys: 2.191 ± 0.059
2.656ProLeu: 2.656 ± 0.069
0.716ProMet: 0.716 ± 0.034
1.713ProAsn: 1.713 ± 0.057
0.515ProPro: 0.515 ± 0.03
1.121ProGln: 1.121 ± 0.046
0.935ProArg: 0.935 ± 0.045
1.986ProSer: 1.986 ± 0.063
1.927ProThr: 1.927 ± 0.055
2.349ProVal: 2.349 ± 0.057
0.285ProTrp: 0.285 ± 0.024
1.301ProTyr: 1.301 ± 0.044
0.0ProXaa: 0.0 ± 0.0
Gln
2.517GlnAla: 2.517 ± 0.072
0.097GlnCys: 0.097 ± 0.012
1.927GlnAsp: 1.927 ± 0.059
2.584GlnGlu: 2.584 ± 0.071
1.334GlnPhe: 1.334 ± 0.049
1.84GlnGly: 1.84 ± 0.055
0.409GlnHis: 0.409 ± 0.029
2.845GlnIle: 2.845 ± 0.068
2.665GlnLys: 2.665 ± 0.065
2.916GlnLeu: 2.916 ± 0.068
0.868GlnMet: 0.868 ± 0.039
1.851GlnAsn: 1.851 ± 0.057
0.859GlnPro: 0.859 ± 0.04
0.951GlnGln: 0.951 ± 0.047
1.08GlnArg: 1.08 ± 0.042
1.83GlnSer: 1.83 ± 0.055
1.651GlnThr: 1.651 ± 0.051
2.587GlnVal: 2.587 ± 0.068
0.208GlnTrp: 0.208 ± 0.021
1.205GlnTyr: 1.205 ± 0.044
0.0GlnXaa: 0.0 ± 0.0
Arg
2.163ArgAla: 2.163 ± 0.066
0.146ArgCys: 0.146 ± 0.017
2.183ArgAsp: 2.183 ± 0.057
2.703ArgGlu: 2.703 ± 0.076
1.573ArgPhe: 1.573 ± 0.054
2.097ArgGly: 2.097 ± 0.065
0.53ArgHis: 0.53 ± 0.024
2.853ArgIle: 2.853 ± 0.073
2.961ArgLys: 2.961 ± 0.074
3.314ArgLeu: 3.314 ± 0.077
0.946ArgMet: 0.946 ± 0.039
1.913ArgAsn: 1.913 ± 0.068
1.077ArgPro: 1.077 ± 0.041
1.383ArgGln: 1.383 ± 0.051
1.577ArgArg: 1.577 ± 0.054
1.856ArgSer: 1.856 ± 0.056
1.649ArgThr: 1.649 ± 0.045
2.355ArgVal: 2.355 ± 0.074
0.232ArgTrp: 0.232 ± 0.018
1.344ArgTyr: 1.344 ± 0.054
0.0ArgXaa: 0.0 ± 0.0
Ser
3.614SerAla: 3.614 ± 0.078
0.289SerCys: 0.289 ± 0.024
4.166SerAsp: 4.166 ± 0.089
4.252SerGlu: 4.252 ± 0.092
3.152SerPhe: 3.152 ± 0.077
4.643SerGly: 4.643 ± 0.096
1.096SerHis: 1.096 ± 0.047
5.395SerIle: 5.395 ± 0.115
5.082SerLys: 5.082 ± 0.092
6.33SerLeu: 6.33 ± 0.096
1.673SerMet: 1.673 ± 0.05
3.563SerAsn: 3.563 ± 0.092
1.86SerPro: 1.86 ± 0.064
2.49SerGln: 2.49 ± 0.057
2.363SerArg: 2.363 ± 0.063
4.51SerSer: 4.51 ± 0.108
3.384SerThr: 3.384 ± 0.088
4.045SerVal: 4.045 ± 0.076
0.588SerTrp: 0.588 ± 0.031
2.662SerTyr: 2.662 ± 0.062
0.0SerXaa: 0.0 ± 0.0
Thr
3.441ThrAla: 3.441 ± 0.085
0.254ThrCys: 0.254 ± 0.024
3.303ThrAsp: 3.303 ± 0.076
3.214ThrGlu: 3.214 ± 0.077
2.466ThrPhe: 2.466 ± 0.071
3.824ThrGly: 3.824 ± 0.096
0.895ThrHis: 0.895 ± 0.038
4.588ThrIle: 4.588 ± 0.091
3.476ThrLys: 3.476 ± 0.072
4.906ThrLeu: 4.906 ± 0.09
1.143ThrMet: 1.143 ± 0.046
2.797ThrAsn: 2.797 ± 0.064
2.14ThrPro: 2.14 ± 0.068
1.407ThrGln: 1.407 ± 0.049
1.708ThrArg: 1.708 ± 0.063
3.605ThrSer: 3.605 ± 0.085
2.878ThrThr: 2.878 ± 0.077
3.775ThrVal: 3.775 ± 0.083
0.44ThrTrp: 0.44 ± 0.025
2.204ThrTyr: 2.204 ± 0.062
0.0ThrXaa: 0.0 ± 0.0
Val
5.044ValAla: 5.044 ± 0.1
0.353ValCys: 0.353 ± 0.022
4.339ValAsp: 4.339 ± 0.091
4.796ValGlu: 4.796 ± 0.096
2.985ValPhe: 2.985 ± 0.063
4.53ValGly: 4.53 ± 0.096
0.933ValHis: 0.933 ± 0.041
5.718ValIle: 5.718 ± 0.108
4.696ValLys: 4.696 ± 0.09
6.192ValLeu: 6.192 ± 0.104
1.593ValMet: 1.593 ± 0.054
3.446ValAsn: 3.446 ± 0.068
2.4ValPro: 2.4 ± 0.061
1.73ValGln: 1.73 ± 0.055
2.31ValArg: 2.31 ± 0.06
4.591ValSer: 4.591 ± 0.082
3.753ValThr: 3.753 ± 0.089
4.902ValVal: 4.902 ± 0.105
0.44ValTrp: 0.44 ± 0.029
2.24ValTyr: 2.24 ± 0.06
0.0ValXaa: 0.0 ± 0.0
Trp
0.418TrpAla: 0.418 ± 0.025
0.057TrpCys: 0.057 ± 0.009
0.515TrpAsp: 0.515 ± 0.028
0.471TrpGlu: 0.471 ± 0.03
0.431TrpPhe: 0.431 ± 0.028
0.56TrpGly: 0.56 ± 0.033
0.157TrpHis: 0.157 ± 0.017
0.682TrpIle: 0.682 ± 0.032
0.55TrpLys: 0.55 ± 0.03
0.813TrpLeu: 0.813 ± 0.041
0.227TrpMet: 0.227 ± 0.018
0.533TrpAsn: 0.533 ± 0.031
0.169TrpPro: 0.169 ± 0.017
0.347TrpGln: 0.347 ± 0.027
0.296TrpArg: 0.296 ± 0.023
0.526TrpSer: 0.526 ± 0.032
0.474TrpThr: 0.474 ± 0.028
0.477TrpVal: 0.477 ± 0.028
0.119TrpTrp: 0.119 ± 0.013
0.31TrpTyr: 0.31 ± 0.023
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.306TyrAla: 2.306 ± 0.065
0.245TyrCys: 0.245 ± 0.021
2.616TyrAsp: 2.616 ± 0.068
2.582TyrGlu: 2.582 ± 0.067
2.172TyrPhe: 2.172 ± 0.076
2.495TyrGly: 2.495 ± 0.062
0.63TyrHis: 0.63 ± 0.03
2.974TyrIle: 2.974 ± 0.067
2.792TyrLys: 2.792 ± 0.074
4.187TyrLeu: 4.187 ± 0.096
0.887TyrMet: 0.887 ± 0.039
2.062TyrAsn: 2.062 ± 0.063
1.409TyrPro: 1.409 ± 0.051
1.584TyrGln: 1.584 ± 0.056
1.426TyrArg: 1.426 ± 0.043
2.621TyrSer: 2.621 ± 0.068
1.889TyrThr: 1.889 ± 0.055
2.186TyrVal: 2.186 ± 0.051
0.324TyrTrp: 0.324 ± 0.021
1.727TyrTyr: 1.727 ± 0.059
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2108 proteins (628882 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski