Amino acid dipepetide frequency for Shuangao sobemo-like virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.739AlaAla: 12.739 ± 4.693
3.185AlaCys: 3.185 ± 0.831
5.308AlaAsp: 5.308 ± 0.441
4.246AlaGlu: 4.246 ± 1.175
4.246AlaPhe: 4.246 ± 0.195
9.554AlaGly: 9.554 ± 1.123
1.062AlaHis: 1.062 ± 0.734
1.062AlaIle: 1.062 ± 0.734
3.185AlaLys: 3.185 ± 0.831
8.493AlaLeu: 8.493 ± 5.868
2.123AlaMet: 2.123 ± 1.272
2.123AlaAsn: 2.123 ± 0.097
5.308AlaPro: 5.308 ± 0.441
1.062AlaGln: 1.062 ± 0.636
4.246AlaArg: 4.246 ± 1.175
7.431AlaSer: 7.431 ± 0.344
4.246AlaThr: 4.246 ± 1.175
5.308AlaVal: 5.308 ± 0.928
2.123AlaTrp: 2.123 ± 1.272
6.369AlaTyr: 6.369 ± 1.077
0.0AlaXaa: 0.0 ± 0.0
Cys
1.062CysAla: 1.062 ± 0.734
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
1.062CysPhe: 1.062 ± 0.636
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
1.062CysIle: 1.062 ± 0.636
5.308CysLys: 5.308 ± 1.811
1.062CysLeu: 1.062 ± 0.734
0.0CysMet: 0.0 ± 0.0
1.062CysAsn: 1.062 ± 0.734
0.0CysPro: 0.0 ± 0.0
2.123CysGln: 2.123 ± 1.467
1.062CysArg: 1.062 ± 0.636
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.246AspAla: 4.246 ± 1.564
0.0AspCys: 0.0 ± 0.0
4.246AspAsp: 4.246 ± 0.195
1.062AspGlu: 1.062 ± 0.636
0.0AspPhe: 0.0 ± 0.0
2.123AspGly: 2.123 ± 0.097
1.062AspHis: 1.062 ± 0.636
0.0AspIle: 0.0 ± 0.0
5.308AspLys: 5.308 ± 1.811
2.123AspLeu: 2.123 ± 1.272
2.123AspMet: 2.123 ± 1.272
1.062AspAsn: 1.062 ± 0.636
5.308AspPro: 5.308 ± 0.441
2.123AspGln: 2.123 ± 1.272
2.123AspArg: 2.123 ± 0.097
2.123AspSer: 2.123 ± 0.097
2.123AspThr: 2.123 ± 0.097
1.062AspVal: 1.062 ± 0.636
2.123AspTrp: 2.123 ± 1.272
5.308AspTyr: 5.308 ± 3.668
0.0AspXaa: 0.0 ± 0.0
Glu
5.308GluAla: 5.308 ± 0.441
2.123GluCys: 2.123 ± 1.467
2.123GluAsp: 2.123 ± 1.467
6.369GluGlu: 6.369 ± 1.077
1.062GluPhe: 1.062 ± 0.636
1.062GluGly: 1.062 ± 0.636
1.062GluHis: 1.062 ± 0.636
1.062GluIle: 1.062 ± 0.734
3.185GluLys: 3.185 ± 0.539
3.185GluLeu: 3.185 ± 1.908
2.123GluMet: 2.123 ± 1.467
1.062GluAsn: 1.062 ± 0.734
4.246GluPro: 4.246 ± 1.175
6.369GluGln: 6.369 ± 1.077
4.246GluArg: 4.246 ± 0.195
4.246GluSer: 4.246 ± 1.564
0.0GluThr: 0.0 ± 0.0
1.062GluVal: 1.062 ± 0.734
0.0GluTrp: 0.0 ± 0.0
3.185GluTyr: 3.185 ± 0.539
0.0GluXaa: 0.0 ± 0.0
Phe
2.123PheAla: 2.123 ± 1.272
0.0PheCys: 0.0 ± 0.0
3.185PheAsp: 3.185 ± 1.908
5.308PheGlu: 5.308 ± 0.928
3.185PhePhe: 3.185 ± 1.908
4.246PheGly: 4.246 ± 0.195
0.0PheHis: 0.0 ± 0.0
2.123PheIle: 2.123 ± 1.272
3.185PheLys: 3.185 ± 1.908
2.123PheLeu: 2.123 ± 1.272
3.185PheMet: 3.185 ± 0.539
1.062PheAsn: 1.062 ± 0.734
0.0PhePro: 0.0 ± 0.0
1.062PheGln: 1.062 ± 0.734
2.123PheArg: 2.123 ± 0.097
2.123PheSer: 2.123 ± 0.097
1.062PheThr: 1.062 ± 0.734
0.0PheVal: 0.0 ± 0.0
2.123PheTrp: 2.123 ± 0.097
3.185PheTyr: 3.185 ± 0.539
0.0PheXaa: 0.0 ± 0.0
Gly
5.308GlyAla: 5.308 ± 0.928
2.123GlyCys: 2.123 ± 0.097
5.308GlyAsp: 5.308 ± 0.441
1.062GlyGlu: 1.062 ± 0.636
3.185GlyPhe: 3.185 ± 0.831
4.246GlyGly: 4.246 ± 1.564
3.185GlyHis: 3.185 ± 0.539
3.185GlyIle: 3.185 ± 2.201
3.185GlyLys: 3.185 ± 2.201
8.493GlyLeu: 8.493 ± 0.39
1.062GlyMet: 1.062 ± 0.734
2.123GlyAsn: 2.123 ± 0.097
3.185GlyPro: 3.185 ± 0.539
1.062GlyGln: 1.062 ± 0.734
1.062GlyArg: 1.062 ± 0.636
7.431GlySer: 7.431 ± 1.026
4.246GlyThr: 4.246 ± 1.564
2.123GlyVal: 2.123 ± 1.467
4.246GlyTrp: 4.246 ± 2.544
1.062GlyTyr: 1.062 ± 0.734
0.0GlyXaa: 0.0 ± 0.0
His
1.062HisAla: 1.062 ± 0.636
0.0HisCys: 0.0 ± 0.0
1.062HisAsp: 1.062 ± 0.636
0.0HisGlu: 0.0 ± 0.0
2.123HisPhe: 2.123 ± 1.272
3.185HisGly: 3.185 ± 2.201
1.062HisHis: 1.062 ± 0.734
1.062HisIle: 1.062 ± 0.734
1.062HisLys: 1.062 ± 0.636
2.123HisLeu: 2.123 ± 1.272
1.062HisMet: 1.062 ± 0.636
1.062HisAsn: 1.062 ± 0.734
0.0HisPro: 0.0 ± 0.0
1.062HisGln: 1.062 ± 0.636
1.062HisArg: 1.062 ± 0.734
1.062HisSer: 1.062 ± 0.636
1.062HisThr: 1.062 ± 0.636
4.246HisVal: 4.246 ± 1.564
0.0HisTrp: 0.0 ± 0.0
1.062HisTyr: 1.062 ± 0.734
0.0HisXaa: 0.0 ± 0.0
Ile
5.308IleAla: 5.308 ± 2.298
0.0IleCys: 0.0 ± 0.0
1.062IleAsp: 1.062 ± 0.636
1.062IleGlu: 1.062 ± 0.734
0.0IlePhe: 0.0 ± 0.0
2.123IleGly: 2.123 ± 0.097
2.123IleHis: 2.123 ± 1.467
0.0IleIle: 0.0 ± 0.0
4.246IleLys: 4.246 ± 1.175
4.246IleLeu: 4.246 ± 0.195
1.062IleMet: 1.062 ± 0.636
1.062IleAsn: 1.062 ± 0.734
2.123IlePro: 2.123 ± 0.097
2.123IleGln: 2.123 ± 1.272
1.062IleArg: 1.062 ± 0.636
1.062IleSer: 1.062 ± 0.636
1.062IleThr: 1.062 ± 0.636
1.062IleVal: 1.062 ± 0.734
0.0IleTrp: 0.0 ± 0.0
2.123IleTyr: 2.123 ± 1.272
0.0IleXaa: 0.0 ± 0.0
Lys
2.123LysAla: 2.123 ± 1.272
0.0LysCys: 0.0 ± 0.0
1.062LysAsp: 1.062 ± 0.636
3.185LysGlu: 3.185 ± 1.908
1.062LysPhe: 1.062 ± 0.734
2.123LysGly: 2.123 ± 1.467
1.062LysHis: 1.062 ± 0.636
4.246LysIle: 4.246 ± 0.195
6.369LysLys: 6.369 ± 0.292
10.616LysLeu: 10.616 ± 4.992
0.0LysMet: 0.0 ± 0.0
1.062LysAsn: 1.062 ± 0.734
4.246LysPro: 4.246 ± 1.175
4.246LysGln: 4.246 ± 1.175
2.123LysArg: 2.123 ± 0.097
4.246LysSer: 4.246 ± 0.195
6.369LysThr: 6.369 ± 0.292
4.246LysVal: 4.246 ± 1.564
0.0LysTrp: 0.0 ± 0.0
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
8.493LeuAla: 8.493 ± 0.39
1.062LeuCys: 1.062 ± 0.636
2.123LeuAsp: 2.123 ± 1.272
8.493LeuGlu: 8.493 ± 0.39
4.246LeuPhe: 4.246 ± 1.564
5.308LeuGly: 5.308 ± 0.441
2.123LeuHis: 2.123 ± 0.097
4.246LeuIle: 4.246 ± 0.195
5.308LeuLys: 5.308 ± 2.298
8.493LeuLeu: 8.493 ± 1.759
1.062LeuMet: 1.062 ± 0.636
2.123LeuAsn: 2.123 ± 0.097
6.369LeuPro: 6.369 ± 1.077
1.062LeuGln: 1.062 ± 0.734
8.493LeuArg: 8.493 ± 3.719
6.369LeuSer: 6.369 ± 1.662
3.185LeuThr: 3.185 ± 1.908
9.554LeuVal: 9.554 ± 2.493
3.185LeuTrp: 3.185 ± 0.539
6.369LeuTyr: 6.369 ± 1.077
0.0LeuXaa: 0.0 ± 0.0
Met
4.246MetAla: 4.246 ± 1.175
1.062MetCys: 1.062 ± 0.636
1.062MetAsp: 1.062 ± 0.636
1.062MetGlu: 1.062 ± 0.734
0.0MetPhe: 0.0 ± 0.0
3.185MetGly: 3.185 ± 0.539
0.0MetHis: 0.0 ± 0.0
1.062MetIle: 1.062 ± 0.636
3.185MetLys: 3.185 ± 1.908
1.062MetLeu: 1.062 ± 0.734
2.123MetMet: 2.123 ± 0.097
1.062MetAsn: 1.062 ± 0.636
1.062MetPro: 1.062 ± 0.734
0.0MetGln: 0.0 ± 0.0
2.123MetArg: 2.123 ± 1.467
1.062MetSer: 1.062 ± 0.636
0.0MetThr: 0.0 ± 0.0
1.062MetVal: 1.062 ± 0.636
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.062AsnAla: 1.062 ± 0.734
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
1.062AsnGlu: 1.062 ± 0.636
3.185AsnPhe: 3.185 ± 0.831
2.123AsnGly: 2.123 ± 1.467
1.062AsnHis: 1.062 ± 0.734
0.0AsnIle: 0.0 ± 0.0
2.123AsnLys: 2.123 ± 0.097
2.123AsnLeu: 2.123 ± 0.097
0.0AsnMet: 0.0 ± 0.0
1.062AsnAsn: 1.062 ± 0.636
2.123AsnPro: 2.123 ± 0.097
0.0AsnGln: 0.0 ± 0.0
1.062AsnArg: 1.062 ± 0.734
7.431AsnSer: 7.431 ± 1.026
0.0AsnThr: 0.0 ± 0.0
0.0AsnVal: 0.0 ± 0.0
1.062AsnTrp: 1.062 ± 0.636
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
4.246ProAla: 4.246 ± 1.564
1.062ProCys: 1.062 ± 0.636
4.246ProAsp: 4.246 ± 0.195
4.246ProGlu: 4.246 ± 0.195
2.123ProPhe: 2.123 ± 1.272
8.493ProGly: 8.493 ± 2.35
2.123ProHis: 2.123 ± 0.097
3.185ProIle: 3.185 ± 0.539
1.062ProLys: 1.062 ± 0.636
7.431ProLeu: 7.431 ± 1.026
2.123ProMet: 2.123 ± 0.097
1.062ProAsn: 1.062 ± 0.636
3.185ProPro: 3.185 ± 0.831
5.308ProGln: 5.308 ± 0.441
0.0ProArg: 0.0 ± 0.0
5.308ProSer: 5.308 ± 2.298
5.308ProThr: 5.308 ± 1.811
3.185ProVal: 3.185 ± 0.539
0.0ProTrp: 0.0 ± 0.0
1.062ProTyr: 1.062 ± 0.734
0.0ProXaa: 0.0 ± 0.0
Gln
7.431GlnAla: 7.431 ± 3.083
0.0GlnCys: 0.0 ± 0.0
2.123GlnAsp: 2.123 ± 0.097
3.185GlnGlu: 3.185 ± 0.831
1.062GlnPhe: 1.062 ± 0.636
0.0GlnGly: 0.0 ± 0.0
1.062GlnHis: 1.062 ± 0.636
1.062GlnIle: 1.062 ± 0.636
2.123GlnLys: 2.123 ± 1.272
5.308GlnLeu: 5.308 ± 0.928
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
3.185GlnPro: 3.185 ± 0.831
3.185GlnGln: 3.185 ± 1.908
3.185GlnArg: 3.185 ± 0.539
3.185GlnSer: 3.185 ± 0.539
3.185GlnThr: 3.185 ± 0.539
8.493GlnVal: 8.493 ± 3.129
1.062GlnTrp: 1.062 ± 0.636
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.123ArgAla: 2.123 ± 0.097
0.0ArgCys: 0.0 ± 0.0
1.062ArgAsp: 1.062 ± 0.734
3.185ArgGlu: 3.185 ± 1.908
2.123ArgPhe: 2.123 ± 1.272
1.062ArgGly: 1.062 ± 0.734
1.062ArgHis: 1.062 ± 0.636
1.062ArgIle: 1.062 ± 0.636
3.185ArgLys: 3.185 ± 0.539
9.554ArgLeu: 9.554 ± 1.123
0.0ArgMet: 0.0 ± 0.0
2.123ArgAsn: 2.123 ± 1.467
2.123ArgPro: 2.123 ± 0.097
1.062ArgGln: 1.062 ± 0.734
6.369ArgArg: 6.369 ± 3.032
5.308ArgSer: 5.308 ± 0.928
1.062ArgThr: 1.062 ± 0.636
10.616ArgVal: 10.616 ± 3.622
3.185ArgTrp: 3.185 ± 0.539
1.062ArgTyr: 1.062 ± 0.636
0.0ArgXaa: 0.0 ± 0.0
Ser
3.185SerAla: 3.185 ± 2.201
3.185SerCys: 3.185 ± 0.539
4.246SerAsp: 4.246 ± 1.564
1.062SerGlu: 1.062 ± 0.734
6.369SerPhe: 6.369 ± 2.447
5.308SerGly: 5.308 ± 0.928
2.123SerHis: 2.123 ± 0.097
2.123SerIle: 2.123 ± 0.097
2.123SerLys: 2.123 ± 0.097
7.431SerLeu: 7.431 ± 0.344
2.123SerMet: 2.123 ± 0.097
1.062SerAsn: 1.062 ± 0.734
11.677SerPro: 11.677 ± 2.59
5.308SerGln: 5.308 ± 0.928
3.185SerArg: 3.185 ± 2.201
8.493SerSer: 8.493 ± 0.39
2.123SerThr: 2.123 ± 0.097
5.308SerVal: 5.308 ± 0.928
1.062SerTrp: 1.062 ± 0.636
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
9.554ThrAla: 9.554 ± 2.986
0.0ThrCys: 0.0 ± 0.0
1.062ThrAsp: 1.062 ± 0.636
2.123ThrGlu: 2.123 ± 1.467
2.123ThrPhe: 2.123 ± 1.467
3.185ThrGly: 3.185 ± 0.831
1.062ThrHis: 1.062 ± 0.636
3.185ThrIle: 3.185 ± 0.539
2.123ThrLys: 2.123 ± 1.272
3.185ThrLeu: 3.185 ± 0.539
0.0ThrMet: 0.0 ± 0.0
1.062ThrAsn: 1.062 ± 0.734
2.123ThrPro: 2.123 ± 0.097
2.123ThrGln: 2.123 ± 0.097
3.185ThrArg: 3.185 ± 0.539
3.185ThrSer: 3.185 ± 0.831
4.246ThrThr: 4.246 ± 0.195
0.0ThrVal: 0.0 ± 0.0
1.062ThrTrp: 1.062 ± 0.636
3.185ThrTyr: 3.185 ± 0.539
0.0ThrXaa: 0.0 ± 0.0
Val
8.493ValAla: 8.493 ± 1.759
0.0ValCys: 0.0 ± 0.0
1.062ValAsp: 1.062 ± 0.734
2.123ValGlu: 2.123 ± 0.097
3.185ValPhe: 3.185 ± 1.908
7.431ValGly: 7.431 ± 2.395
1.062ValHis: 1.062 ± 0.734
2.123ValIle: 2.123 ± 0.097
2.123ValLys: 2.123 ± 1.467
3.185ValLeu: 3.185 ± 0.831
2.123ValMet: 2.123 ± 0.587
2.123ValAsn: 2.123 ± 0.097
5.308ValPro: 5.308 ± 0.441
5.308ValGln: 5.308 ± 0.441
5.308ValArg: 5.308 ± 0.928
2.123ValSer: 2.123 ± 1.467
5.308ValThr: 5.308 ± 2.298
5.308ValVal: 5.308 ± 0.928
0.0ValTrp: 0.0 ± 0.0
3.185ValTyr: 3.185 ± 0.539
0.0ValXaa: 0.0 ± 0.0
Trp
2.123TrpAla: 2.123 ± 0.097
0.0TrpCys: 0.0 ± 0.0
3.185TrpAsp: 3.185 ± 1.908
1.062TrpGlu: 1.062 ± 0.734
1.062TrpPhe: 1.062 ± 0.636
0.0TrpGly: 0.0 ± 0.0
1.062TrpHis: 1.062 ± 0.636
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
4.246TrpLeu: 4.246 ± 1.175
1.062TrpMet: 1.062 ± 0.636
2.123TrpAsn: 2.123 ± 1.272
1.062TrpPro: 1.062 ± 0.636
0.0TrpGln: 0.0 ± 0.0
2.123TrpArg: 2.123 ± 1.272
0.0TrpSer: 0.0 ± 0.0
1.062TrpThr: 1.062 ± 0.636
1.062TrpVal: 1.062 ± 0.636
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.185TyrAla: 3.185 ± 0.831
0.0TyrCys: 0.0 ± 0.0
2.123TyrAsp: 2.123 ± 0.097
3.185TyrGlu: 3.185 ± 0.831
0.0TyrPhe: 0.0 ± 0.0
2.123TyrGly: 2.123 ± 0.097
1.062TyrHis: 1.062 ± 0.734
1.062TyrIle: 1.062 ± 0.636
0.0TyrLys: 0.0 ± 0.0
3.185TyrLeu: 3.185 ± 0.539
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
2.123TyrPro: 2.123 ± 1.272
4.246TyrGln: 4.246 ± 1.175
3.185TyrArg: 3.185 ± 1.908
5.308TyrSer: 5.308 ± 0.928
2.123TyrThr: 2.123 ± 0.097
4.246TyrVal: 4.246 ± 1.564
0.0TyrTrp: 0.0 ± 0.0
1.062TyrTyr: 1.062 ± 0.734
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (943 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski