Amino acid dipepetide frequency for Alternanthera yellow vein virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.479AlaAla: 5.479 ± 1.478
1.826AlaCys: 1.826 ± 1.158
2.74AlaAsp: 2.74 ± 0.998
1.826AlaGlu: 1.826 ± 1.461
1.826AlaPhe: 1.826 ± 1.158
0.0AlaGly: 0.0 ± 0.0
0.0AlaHis: 0.0 ± 0.0
3.653AlaIle: 3.653 ± 1.669
2.74AlaLys: 2.74 ± 1.149
5.479AlaLeu: 5.479 ± 1.85
0.913AlaMet: 0.913 ± 0.778
2.74AlaAsn: 2.74 ± 1.443
3.653AlaPro: 3.653 ± 1.115
2.74AlaGln: 2.74 ± 1.27
4.566AlaArg: 4.566 ± 2.552
4.566AlaSer: 4.566 ± 2.048
5.479AlaThr: 5.479 ± 3.638
2.74AlaVal: 2.74 ± 2.758
0.913AlaTrp: 0.913 ± 0.699
2.74AlaTyr: 2.74 ± 1.267
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.913CysGlu: 0.913 ± 0.778
1.826CysPhe: 1.826 ± 1.015
1.826CysGly: 1.826 ± 1.055
1.826CysHis: 1.826 ± 1.282
0.913CysIle: 0.913 ± 0.778
0.913CysLys: 0.913 ± 0.778
0.913CysLeu: 0.913 ± 1.114
0.913CysMet: 0.913 ± 0.919
1.826CysAsn: 1.826 ± 1.144
2.74CysPro: 2.74 ± 1.776
0.913CysGln: 0.913 ± 1.114
0.913CysArg: 0.913 ± 0.699
3.653CysSer: 3.653 ± 1.955
1.826CysThr: 1.826 ± 1.235
0.913CysVal: 0.913 ± 0.778
0.0CysTrp: 0.0 ± 0.0
0.913CysTyr: 0.913 ± 0.919
0.0CysXaa: 0.0 ± 0.0
Asp
1.826AspAla: 1.826 ± 1.398
0.913AspCys: 0.913 ± 1.038
0.913AspAsp: 0.913 ± 0.699
1.826AspGlu: 1.826 ± 0.785
0.0AspPhe: 0.0 ± 0.0
2.74AspGly: 2.74 ± 2.096
1.826AspHis: 1.826 ± 1.282
2.74AspIle: 2.74 ± 1.212
0.0AspLys: 0.0 ± 0.0
8.219AspLeu: 8.219 ± 2.488
0.913AspMet: 0.913 ± 0.778
3.653AspAsn: 3.653 ± 1.269
1.826AspPro: 1.826 ± 0.988
1.826AspGln: 1.826 ± 1.398
1.826AspArg: 1.826 ± 1.556
6.393AspSer: 6.393 ± 2.083
3.653AspThr: 3.653 ± 2.564
5.479AspVal: 5.479 ± 2.356
1.826AspTrp: 1.826 ± 1.398
0.913AspTyr: 0.913 ± 0.699
0.0AspXaa: 0.0 ± 0.0
Glu
3.653GluAla: 3.653 ± 1.275
0.0GluCys: 0.0 ± 0.0
2.74GluAsp: 2.74 ± 1.291
5.479GluGlu: 5.479 ± 4.193
2.74GluPhe: 2.74 ± 1.457
6.393GluGly: 6.393 ± 1.318
0.913GluHis: 0.913 ± 1.114
1.826GluIle: 1.826 ± 1.015
3.653GluLys: 3.653 ± 1.571
2.74GluLeu: 2.74 ± 1.443
0.0GluMet: 0.0 ± 0.0
3.653GluAsn: 3.653 ± 2.305
1.826GluPro: 1.826 ± 1.158
2.74GluGln: 2.74 ± 0.996
0.913GluArg: 0.913 ± 0.699
0.0GluSer: 0.0 ± 0.0
1.826GluThr: 1.826 ± 1.144
0.0GluVal: 0.0 ± 0.0
1.826GluTrp: 1.826 ± 1.055
1.826GluTyr: 1.826 ± 1.015
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.913PheCys: 0.913 ± 0.778
3.653PheAsp: 3.653 ± 1.889
1.826PheGlu: 1.826 ± 0.785
1.826PhePhe: 1.826 ± 1.398
1.826PheGly: 1.826 ± 1.235
0.913PheHis: 0.913 ± 0.699
2.74PheIle: 2.74 ± 1.443
2.74PheLys: 2.74 ± 2.013
6.393PheLeu: 6.393 ± 2.905
1.826PheMet: 1.826 ± 1.398
4.566PheAsn: 4.566 ± 2.882
0.913PhePro: 0.913 ± 0.919
1.826PheGln: 1.826 ± 1.055
1.826PheArg: 1.826 ± 0.988
1.826PheSer: 1.826 ± 1.235
0.913PheThr: 0.913 ± 1.038
0.913PheVal: 0.913 ± 0.699
1.826PheTrp: 1.826 ± 1.556
0.913PheTyr: 0.913 ± 0.778
0.0PheXaa: 0.0 ± 0.0
Gly
2.74GlyAla: 2.74 ± 1.291
1.826GlyCys: 1.826 ± 1.235
3.653GlyAsp: 3.653 ± 1.513
1.826GlyGlu: 1.826 ± 1.178
2.74GlyPhe: 2.74 ± 2.145
2.74GlyGly: 2.74 ± 1.267
0.913GlyHis: 0.913 ± 0.699
3.653GlyIle: 3.653 ± 0.991
4.566GlyLys: 4.566 ± 1.989
1.826GlyLeu: 1.826 ± 1.055
0.913GlyMet: 0.913 ± 0.625
2.74GlyAsn: 2.74 ± 1.457
2.74GlyPro: 2.74 ± 1.267
1.826GlyGln: 1.826 ± 0.785
2.74GlyArg: 2.74 ± 1.457
3.653GlySer: 3.653 ± 1.492
4.566GlyThr: 4.566 ± 1.069
1.826GlyVal: 1.826 ± 2.227
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
2.74HisAla: 2.74 ± 0.998
2.74HisCys: 2.74 ± 1.149
2.74HisAsp: 2.74 ± 2.156
0.913HisGlu: 0.913 ± 0.699
1.826HisPhe: 1.826 ± 0.988
0.0HisGly: 0.0 ± 0.0
1.826HisHis: 1.826 ± 2.076
1.826HisIle: 1.826 ± 1.015
0.913HisLys: 0.913 ± 1.114
0.913HisLeu: 0.913 ± 0.699
0.0HisMet: 0.0 ± 0.0
3.653HisAsn: 3.653 ± 1.335
0.913HisPro: 0.913 ± 1.09
2.74HisGln: 2.74 ± 1.041
3.653HisArg: 3.653 ± 2.47
0.913HisSer: 0.913 ± 0.919
3.653HisThr: 3.653 ± 2.303
2.74HisVal: 2.74 ± 1.489
0.0HisTrp: 0.0 ± 0.0
1.826HisTyr: 1.826 ± 1.055
0.0HisXaa: 0.0 ± 0.0
Ile
0.913IleAla: 0.913 ± 0.919
0.913IleCys: 0.913 ± 1.114
3.653IleAsp: 3.653 ± 2.028
4.566IleGlu: 4.566 ± 2.66
2.74IlePhe: 2.74 ± 1.457
1.826IleGly: 1.826 ± 0.785
1.826IleHis: 1.826 ± 1.461
5.479IleIle: 5.479 ± 2.876
10.959IleLys: 10.959 ± 1.544
0.913IleLeu: 0.913 ± 0.699
0.0IleMet: 0.0 ± 0.0
3.653IleAsn: 3.653 ± 0.995
1.826IlePro: 1.826 ± 1.055
1.826IleGln: 1.826 ± 1.015
6.393IleArg: 6.393 ± 2.649
5.479IleSer: 5.479 ± 1.576
4.566IleThr: 4.566 ± 2.882
1.826IleVal: 1.826 ± 0.785
1.826IleTrp: 1.826 ± 1.178
2.74IleTyr: 2.74 ± 1.656
0.0IleXaa: 0.0 ± 0.0
Lys
2.74LysAla: 2.74 ± 0.837
0.913LysCys: 0.913 ± 1.114
2.74LysAsp: 2.74 ± 2.096
4.566LysGlu: 4.566 ± 2.552
2.74LysPhe: 2.74 ± 1.34
1.826LysGly: 1.826 ± 1.055
2.74LysHis: 2.74 ± 0.837
2.74LysIle: 2.74 ± 1.656
1.826LysLys: 1.826 ± 0.785
0.913LysLeu: 0.913 ± 1.09
0.0LysMet: 0.0 ± 0.0
5.479LysAsn: 5.479 ± 2.534
3.653LysPro: 3.653 ± 1.087
0.913LysGln: 0.913 ± 0.778
4.566LysArg: 4.566 ± 2.508
2.74LysSer: 2.74 ± 1.399
2.74LysThr: 2.74 ± 1.27
2.74LysVal: 2.74 ± 1.407
0.0LysTrp: 0.0 ± 0.0
2.74LysTyr: 2.74 ± 1.27
0.0LysXaa: 0.0 ± 0.0
Leu
1.826LeuAla: 1.826 ± 1.055
3.653LeuCys: 3.653 ± 1.27
4.566LeuAsp: 4.566 ± 1.753
1.826LeuGlu: 1.826 ± 1.398
0.0LeuPhe: 0.0 ± 0.0
4.566LeuGly: 4.566 ± 2.169
3.653LeuHis: 3.653 ± 0.995
2.74LeuIle: 2.74 ± 2.077
2.74LeuLys: 2.74 ± 1.041
4.566LeuLeu: 4.566 ± 1.966
2.74LeuMet: 2.74 ± 2.305
5.479LeuAsn: 5.479 ± 1.419
0.913LeuPro: 0.913 ± 1.038
6.393LeuGln: 6.393 ± 0.884
6.393LeuArg: 6.393 ± 3.664
3.653LeuSer: 3.653 ± 1.685
6.393LeuThr: 6.393 ± 3.318
2.74LeuVal: 2.74 ± 1.399
0.913LeuTrp: 0.913 ± 1.114
5.479LeuTyr: 5.479 ± 1.903
0.0LeuXaa: 0.0 ± 0.0
Met
1.826MetAla: 1.826 ± 1.556
0.0MetCys: 0.0 ± 0.0
1.826MetAsp: 1.826 ± 1.178
1.826MetGlu: 1.826 ± 2.179
1.826MetPhe: 1.826 ± 1.235
0.913MetGly: 0.913 ± 0.699
0.0MetHis: 0.0 ± 0.0
1.826MetIle: 1.826 ± 1.556
0.913MetLys: 0.913 ± 1.114
3.653MetLeu: 3.653 ± 3.338
0.913MetMet: 0.913 ± 0.979
0.913MetAsn: 0.913 ± 0.778
0.913MetPro: 0.913 ± 0.699
0.0MetGln: 0.0 ± 0.0
1.826MetArg: 1.826 ± 1.055
1.826MetSer: 1.826 ± 0.785
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
1.826MetTrp: 1.826 ± 0.988
2.74MetTyr: 2.74 ± 2.334
0.0MetXaa: 0.0 ± 0.0
Asn
3.653AsnAla: 3.653 ± 0.995
0.913AsnCys: 0.913 ± 0.699
1.826AsnAsp: 1.826 ± 0.785
1.826AsnGlu: 1.826 ± 0.785
2.74AsnPhe: 2.74 ± 0.837
0.913AsnGly: 0.913 ± 1.114
5.479AsnHis: 5.479 ± 3.313
4.566AsnIle: 4.566 ± 1.502
1.826AsnLys: 1.826 ± 1.398
3.653AsnLeu: 3.653 ± 2.03
1.826AsnMet: 1.826 ± 1.536
3.653AsnAsn: 3.653 ± 1.634
5.479AsnPro: 5.479 ± 1.419
1.826AsnGln: 1.826 ± 1.055
1.826AsnArg: 1.826 ± 1.144
1.826AsnSer: 1.826 ± 1.144
4.566AsnThr: 4.566 ± 1.239
2.74AsnVal: 2.74 ± 1.27
0.913AsnTrp: 0.913 ± 0.699
3.653AsnTyr: 3.653 ± 1.331
0.0AsnXaa: 0.0 ± 0.0
Pro
0.913ProAla: 0.913 ± 1.038
2.74ProCys: 2.74 ± 1.941
2.74ProAsp: 2.74 ± 1.407
0.913ProGlu: 0.913 ± 0.699
2.74ProPhe: 2.74 ± 1.27
1.826ProGly: 1.826 ± 1.398
4.566ProHis: 4.566 ± 2.373
5.479ProIle: 5.479 ± 2.201
0.913ProLys: 0.913 ± 0.699
2.74ProLeu: 2.74 ± 1.27
2.74ProMet: 2.74 ± 1.744
2.74ProAsn: 2.74 ± 1.291
3.653ProPro: 3.653 ± 2.176
1.826ProGln: 1.826 ± 1.476
3.653ProArg: 3.653 ± 1.272
3.653ProSer: 3.653 ± 2.184
4.566ProThr: 4.566 ± 1.977
4.566ProVal: 4.566 ± 1.426
0.913ProTrp: 0.913 ± 0.699
2.74ProTyr: 2.74 ± 1.746
0.0ProXaa: 0.0 ± 0.0
Gln
6.393GlnAla: 6.393 ± 1.788
0.913GlnCys: 0.913 ± 0.699
0.913GlnAsp: 0.913 ± 1.038
3.653GlnGlu: 3.653 ± 1.935
2.74GlnPhe: 2.74 ± 1.34
0.0GlnGly: 0.0 ± 0.0
0.913GlnHis: 0.913 ± 1.038
3.653GlnIle: 3.653 ± 2.03
0.913GlnLys: 0.913 ± 0.919
3.653GlnLeu: 3.653 ± 1.314
0.913GlnMet: 0.913 ± 1.038
0.0GlnAsn: 0.0 ± 0.0
4.566GlnPro: 4.566 ± 1.314
3.653GlnGln: 3.653 ± 1.083
0.913GlnArg: 0.913 ± 0.699
4.566GlnSer: 4.566 ± 1.769
8.219GlnThr: 8.219 ± 2.506
3.653GlnVal: 3.653 ± 0.991
0.913GlnTrp: 0.913 ± 0.778
1.826GlnTyr: 1.826 ± 0.785
0.0GlnXaa: 0.0 ± 0.0
Arg
6.393ArgAla: 6.393 ± 1.955
2.74ArgCys: 2.74 ± 2.144
3.653ArgAsp: 3.653 ± 1.374
3.653ArgGlu: 3.653 ± 1.331
4.566ArgPhe: 4.566 ± 2.131
2.74ArgGly: 2.74 ± 1.041
1.826ArgHis: 1.826 ± 1.407
4.566ArgIle: 4.566 ± 2.048
4.566ArgLys: 4.566 ± 1.305
6.393ArgLeu: 6.393 ± 1.837
0.913ArgMet: 0.913 ± 0.778
0.0ArgAsn: 0.0 ± 0.0
5.479ArgPro: 5.479 ± 1.031
3.653ArgGln: 3.653 ± 1.314
7.306ArgArg: 7.306 ± 4.004
2.74ArgSer: 2.74 ± 1.267
2.74ArgThr: 2.74 ± 1.545
7.306ArgVal: 7.306 ± 1.528
0.0ArgTrp: 0.0 ± 0.0
0.913ArgTyr: 0.913 ± 0.919
0.0ArgXaa: 0.0 ± 0.0
Ser
3.653SerAla: 3.653 ± 1.275
0.0SerCys: 0.0 ± 0.0
4.566SerAsp: 4.566 ± 2.912
0.0SerGlu: 0.0 ± 0.0
2.74SerPhe: 2.74 ± 0.837
3.653SerGly: 3.653 ± 1.504
2.74SerHis: 2.74 ± 0.996
2.74SerIle: 2.74 ± 1.041
4.566SerLys: 4.566 ± 2.16
2.74SerLeu: 2.74 ± 1.973
0.913SerMet: 0.913 ± 1.09
2.74SerAsn: 2.74 ± 1.267
10.046SerPro: 10.046 ± 1.933
4.566SerGln: 4.566 ± 2.688
10.046SerArg: 10.046 ± 4.517
13.699SerSer: 13.699 ± 3.471
3.653SerThr: 3.653 ± 2.194
1.826SerVal: 1.826 ± 1.158
0.0SerTrp: 0.0 ± 0.0
0.913SerTyr: 0.913 ± 0.699
0.0SerXaa: 0.0 ± 0.0
Thr
5.479ThrAla: 5.479 ± 1.511
0.913ThrCys: 0.913 ± 1.114
0.913ThrAsp: 0.913 ± 0.699
1.826ThrGlu: 1.826 ± 0.785
1.826ThrPhe: 1.826 ± 1.398
7.306ThrGly: 7.306 ± 1.751
2.74ThrHis: 2.74 ± 1.784
3.653ThrIle: 3.653 ± 1.272
0.913ThrLys: 0.913 ± 0.699
6.393ThrLeu: 6.393 ± 3.35
1.826ThrMet: 1.826 ± 1.144
2.74ThrAsn: 2.74 ± 0.837
2.74ThrPro: 2.74 ± 0.996
5.479ThrGln: 5.479 ± 2.829
4.566ThrArg: 4.566 ± 2.46
6.393ThrSer: 6.393 ± 2.428
3.653ThrThr: 3.653 ± 1.52
4.566ThrVal: 4.566 ± 1.939
0.913ThrTrp: 0.913 ± 1.114
3.653ThrTyr: 3.653 ± 2.176
0.0ThrXaa: 0.0 ± 0.0
Val
0.0ValAla: 0.0 ± 0.0
0.913ValCys: 0.913 ± 0.699
1.826ValAsp: 1.826 ± 1.055
3.653ValGlu: 3.653 ± 3.678
0.913ValPhe: 0.913 ± 1.114
0.913ValGly: 0.913 ± 0.778
0.913ValHis: 0.913 ± 0.919
4.566ValIle: 4.566 ± 2.107
2.74ValLys: 2.74 ± 1.443
3.653ValLeu: 3.653 ± 1.257
3.653ValMet: 3.653 ± 1.257
1.826ValAsn: 1.826 ± 1.015
3.653ValPro: 3.653 ± 1.087
7.306ValGln: 7.306 ± 1.483
2.74ValArg: 2.74 ± 2.334
2.74ValSer: 2.74 ± 1.746
3.653ValThr: 3.653 ± 2.123
2.74ValVal: 2.74 ± 1.941
0.0ValTrp: 0.0 ± 0.0
4.566ValTyr: 4.566 ± 1.305
0.0ValXaa: 0.0 ± 0.0
Trp
2.74TrpAla: 2.74 ± 2.096
0.0TrpCys: 0.0 ± 0.0
0.913TrpAsp: 0.913 ± 0.919
0.913TrpGlu: 0.913 ± 1.114
0.0TrpPhe: 0.0 ± 0.0
0.913TrpGly: 0.913 ± 0.699
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.913TrpLeu: 0.913 ± 0.778
0.913TrpMet: 0.913 ± 0.778
0.913TrpAsn: 0.913 ± 1.114
0.0TrpPro: 0.0 ± 0.0
0.913TrpGln: 0.913 ± 0.699
2.74TrpArg: 2.74 ± 1.041
0.913TrpSer: 0.913 ± 0.778
0.913TrpThr: 0.913 ± 1.114
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.913TrpTyr: 0.913 ± 0.699
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.653TyrAla: 3.653 ± 1.492
0.913TyrCys: 0.913 ± 0.919
2.74TyrAsp: 2.74 ± 1.746
0.913TyrGlu: 0.913 ± 0.778
1.826TyrPhe: 1.826 ± 1.178
4.566TyrGly: 4.566 ± 1.501
0.913TyrHis: 0.913 ± 0.699
4.566TyrIle: 4.566 ± 0.904
0.913TyrLys: 0.913 ± 0.699
4.566TyrLeu: 4.566 ± 1.647
1.826TyrMet: 1.826 ± 1.068
2.74TyrAsn: 2.74 ± 0.837
0.0TyrPro: 0.0 ± 0.0
0.0TyrGln: 0.0 ± 0.0
2.74TyrArg: 2.74 ± 2.334
4.566TyrSer: 4.566 ± 1.977
0.913TyrThr: 0.913 ± 1.114
3.653TyrVal: 3.653 ± 1.422
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1096 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski