Sideroxydans lithotrophicus (strain ES-1)

Taxonomy: cellular organisms; Bacteria; Proteobacteria; Betaproteobacteria; Nitrosomonadales; Gallionellaceae; Sideroxydans; Sideroxydans lithotrophicus

Average proteome isoelectric point is 6.59

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 2977 proteins (isoelectric point calculated using IPC2_protein)

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Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>tr|D5CSF1|D5CSF1_SIDLE Glutamine-dependent NAD(+) synthetase OS=Sideroxydans lithotrophicus (strain ES-1) OX=580332 GN=nadE PE=3 SV=1
MM1 pKa = 7.84CLTSLPIAGTVKK13 pKa = 8.83ITSPFGMRR21 pKa = 11.84SGTNHH26 pKa = 6.63AGIDD30 pKa = 3.27IRR32 pKa = 11.84ASVGTGVFASGAGTVVRR49 pKa = 11.84ASDD52 pKa = 3.43NPGPHH57 pKa = 6.59NYY59 pKa = 10.16GNVVVIDD66 pKa = 3.37HH67 pKa = 6.65GIIEE71 pKa = 4.49GEE73 pKa = 4.24HH74 pKa = 6.26VYY76 pKa = 10.94SLYY79 pKa = 11.33AHH81 pKa = 7.14LSEE84 pKa = 5.07FDD86 pKa = 3.18SALAVGQVVAAGQPLGLSGGKK107 pKa = 9.72KK108 pKa = 9.24GAPGSGSSQDD118 pKa = 3.29PHH120 pKa = 8.26LHH122 pKa = 6.01FEE124 pKa = 4.46VIKK127 pKa = 10.92SKK129 pKa = 9.63TEE131 pKa = 3.96IKK133 pKa = 10.15WNTTGAMGYY142 pKa = 8.5PGKK145 pKa = 10.37VDD147 pKa = 4.75RR148 pKa = 11.84VNPWPEE154 pKa = 3.72LFGTCDD160 pKa = 3.66LPSPGMPLQLSTSLNATKK178 pKa = 10.41QFNQRR183 pKa = 11.84FGDD186 pKa = 4.08PLTLDD191 pKa = 4.01LNGDD195 pKa = 4.67GINTVPLTNPPILFDD210 pKa = 3.57HH211 pKa = 6.7TGSGIKK217 pKa = 9.4TGTGWIAPDD226 pKa = 4.36DD227 pKa = 4.24GFLVLDD233 pKa = 4.1RR234 pKa = 11.84NGNGTIDD241 pKa = 3.41NGTEE245 pKa = 3.98LFGDD249 pKa = 3.76STPILDD255 pKa = 4.29ANGNVIGKK263 pKa = 9.65AKK265 pKa = 10.74NGFDD269 pKa = 4.89ALAQLDD275 pKa = 4.36TNHH278 pKa = 7.07DD279 pKa = 4.55GIVDD283 pKa = 3.61AQDD286 pKa = 3.99ANFFDD291 pKa = 4.05LQVWQDD297 pKa = 3.57LNQDD301 pKa = 4.58GISQANEE308 pKa = 3.39LRR310 pKa = 11.84YY311 pKa = 9.69LADD314 pKa = 4.43DD315 pKa = 4.89LNITSINVAATQHH328 pKa = 5.2SQMLASGNQMADD340 pKa = 3.09LGSFTYY346 pKa = 11.06ADD348 pKa = 3.94GSTGATGSVSNMADD362 pKa = 2.81INLALDD368 pKa = 3.57TFHH371 pKa = 6.96RR372 pKa = 11.84TFVTPIPLTPAAEE385 pKa = 4.22QLPDD389 pKa = 3.43MQGSGKK395 pKa = 9.82VRR397 pKa = 11.84DD398 pKa = 3.65LSEE401 pKa = 4.26AVSLSSSLEE410 pKa = 3.86AALTQYY416 pKa = 11.46SNAGTRR422 pKa = 11.84DD423 pKa = 3.32EE424 pKa = 4.46QYY426 pKa = 12.01ALIDD430 pKa = 3.58NLIAEE435 pKa = 4.62WGKK438 pKa = 10.98SSGFADD444 pKa = 3.62MQTRR448 pKa = 11.84AAANGYY454 pKa = 6.2TLVYY458 pKa = 10.67AGLTPTQQAHH468 pKa = 6.37LSVLEE473 pKa = 3.9QFTGSSYY480 pKa = 10.96FRR482 pKa = 11.84MPWEE486 pKa = 4.6GNSGAMGASQGMTVCYY502 pKa = 10.26DD503 pKa = 3.54GNPKK507 pKa = 10.03HH508 pKa = 6.81IRR510 pKa = 11.84IDD512 pKa = 3.58LSPRR516 pKa = 11.84FGQTRR521 pKa = 11.84MLDD524 pKa = 3.21DD525 pKa = 4.13TYY527 pKa = 11.49AILRR531 pKa = 11.84DD532 pKa = 3.6AVYY535 pKa = 10.22QALLPQTRR543 pKa = 11.84LLPYY547 pKa = 10.28LDD549 pKa = 4.12AVGLKK554 pKa = 10.08QEE556 pKa = 5.28DD557 pKa = 3.69GDD559 pKa = 4.25LVYY562 pKa = 11.2DD563 pKa = 3.98FVNVQEE569 pKa = 4.95LFLAQILANPDD580 pKa = 3.12KK581 pKa = 11.17AIVDD585 pKa = 3.7LVEE588 pKa = 4.34FNRR591 pKa = 11.84YY592 pKa = 8.57GKK594 pKa = 10.15DD595 pKa = 3.44YY596 pKa = 10.59FKK598 pKa = 11.32SSDD601 pKa = 3.14WEE603 pKa = 4.28TQGWQLLGDD612 pKa = 4.05TLNDD616 pKa = 3.07ITLTNPTLTPAIQKK630 pKa = 8.31TLADD634 pKa = 4.35FNINMDD640 pKa = 3.53GQPNQKK646 pKa = 10.57ANAEE650 pKa = 4.07VQIAKK655 pKa = 10.18KK656 pKa = 10.54DD657 pKa = 3.6GSTLNGLWNGGVLVGNDD674 pKa = 3.68GNDD677 pKa = 3.49VLNGGYY683 pKa = 10.03YY684 pKa = 10.66GNNILLGGAGDD695 pKa = 4.11DD696 pKa = 4.22VITGGMLATNILQGGAGDD714 pKa = 4.53DD715 pKa = 3.7VLKK718 pKa = 11.02GGWYY722 pKa = 10.32NDD724 pKa = 3.57TLQGGDD730 pKa = 3.93GNDD733 pKa = 3.64NLDD736 pKa = 4.06GGWGNDD742 pKa = 3.56VLDD745 pKa = 4.89GGAGDD750 pKa = 5.88DD751 pKa = 4.48ILNGDD756 pKa = 4.04TGNDD760 pKa = 3.27VLTGGTGNDD769 pKa = 3.11ILQGGSGNDD778 pKa = 2.95TYY780 pKa = 11.65VYY782 pKa = 11.02NKK784 pKa = 10.52GDD786 pKa = 3.55GADD789 pKa = 3.56IIIDD793 pKa = 3.16NSYY796 pKa = 10.64YY797 pKa = 9.39HH798 pKa = 6.38TANNILQLGAGITADD813 pKa = 3.98TLFVTYY819 pKa = 10.46DD820 pKa = 3.46SVAVTVLLDD829 pKa = 3.39MGNGDD834 pKa = 4.81SIHH837 pKa = 6.7IGSPTDD843 pKa = 3.6LAIQTIQLADD853 pKa = 3.73GSTLDD858 pKa = 3.12VDD860 pKa = 3.62TLLRR864 pKa = 11.84QRR866 pKa = 11.84SLVQNGTDD874 pKa = 3.91GADD877 pKa = 2.96ILQGSDD883 pKa = 2.67SAYY886 pKa = 10.73ADD888 pKa = 3.74VLSGGAGDD896 pKa = 5.71DD897 pKa = 3.8ILNGGAGNDD906 pKa = 3.66VLNGGTGNDD915 pKa = 3.6VLNGGTGSDD924 pKa = 3.46TYY926 pKa = 11.46VYY928 pKa = 11.09NLGDD932 pKa = 3.71GSDD935 pKa = 4.43RR936 pKa = 11.84ITDD939 pKa = 3.42SGRR942 pKa = 11.84QYY944 pKa = 11.47YY945 pKa = 10.13DD946 pKa = 2.57WQTRR950 pKa = 11.84QYY952 pKa = 11.11RR953 pKa = 11.84NADD956 pKa = 3.64TNVLSFGAGITADD969 pKa = 4.16MLTVSYY975 pKa = 11.27DD976 pKa = 3.71SVTLAATLVLSNGDD990 pKa = 3.85TIEE993 pKa = 4.91IGAPDD998 pKa = 3.86NLAIQTLQFADD1009 pKa = 4.17GSTLDD1014 pKa = 3.42VNTLVGQQTLTQVGTEE1030 pKa = 4.21GNDD1033 pKa = 3.14VLTGSDD1039 pKa = 3.45SIMFRR1044 pKa = 11.84DD1045 pKa = 4.48SIQGLGGDD1053 pKa = 3.6DD1054 pKa = 3.56TLYY1057 pKa = 11.24GGAGGDD1063 pKa = 3.94TLDD1066 pKa = 4.6GGAGNDD1072 pKa = 3.55TLYY1075 pKa = 10.88GQSGNDD1081 pKa = 3.19ILIGGTGNDD1090 pKa = 3.71TLSGGGGNDD1099 pKa = 3.0TYY1101 pKa = 11.54VYY1103 pKa = 11.02NLGDD1107 pKa = 3.81GADD1110 pKa = 3.89TIIDD1114 pKa = 3.67LVGTHH1119 pKa = 6.62PEE1121 pKa = 4.35GWGQWPTPDD1130 pKa = 4.18INTLSFGSGITPDD1143 pKa = 3.17MVKK1146 pKa = 9.91IRR1148 pKa = 11.84FVPDD1152 pKa = 3.44PADD1155 pKa = 3.61PTGSTGSIVFDD1166 pKa = 4.76LGNGDD1171 pKa = 4.23TINVGSGIQTSSNYY1185 pKa = 9.39NLSVQTVQFADD1196 pKa = 4.09GSSFTIDD1203 pKa = 3.09QMLRR1207 pKa = 11.84RR1208 pKa = 11.84NKK1210 pKa = 10.09FYY1212 pKa = 11.53VEE1214 pKa = 4.06GTATAEE1220 pKa = 4.02SMTGFNHH1227 pKa = 7.1FYY1229 pKa = 11.08GNNLQGMGGDD1239 pKa = 3.7DD1240 pKa = 3.75TLTGTEE1246 pKa = 4.46GNDD1249 pKa = 3.23ILSGGAGNDD1258 pKa = 3.29VLIGMGGSDD1267 pKa = 3.25TYY1269 pKa = 10.85IYY1271 pKa = 11.03NFGDD1275 pKa = 3.77GADD1278 pKa = 3.89QIVDD1282 pKa = 4.01YY1283 pKa = 10.52PSGTQTASGWVAGTNTLSFGTGITADD1309 pKa = 3.79MVTPRR1314 pKa = 11.84YY1315 pKa = 9.59DD1316 pKa = 3.16RR1317 pKa = 11.84SVNAIVLDD1325 pKa = 4.35LGNGDD1330 pKa = 4.63SINVGAADD1338 pKa = 4.35ALTIQQLKK1346 pKa = 9.53FADD1349 pKa = 4.23GSTMNLNDD1357 pKa = 4.02FLGQKK1362 pKa = 8.52TLTEE1366 pKa = 4.31VGTSGSDD1373 pKa = 3.18VLYY1376 pKa = 10.75GSNSSSYY1383 pKa = 11.25SDD1385 pKa = 3.57TLIGGAGNDD1394 pKa = 3.73LLIGGRR1400 pKa = 11.84GNDD1403 pKa = 2.95TYY1405 pKa = 11.73VFNLGDD1411 pKa = 3.77GADD1414 pKa = 4.05NIIDD1418 pKa = 3.72TGVSDD1423 pKa = 3.77MAHH1426 pKa = 5.87GLGINVLSFGAGITADD1442 pKa = 4.13MITVQLDD1449 pKa = 3.72GEE1451 pKa = 4.52FGDD1454 pKa = 3.8VTLDD1458 pKa = 3.39LGGGDD1463 pKa = 4.07SVTIGQIDD1471 pKa = 5.24LNTNDD1476 pKa = 4.48LNGISIEE1483 pKa = 3.99QLKK1486 pKa = 10.0FADD1489 pKa = 4.68GSTITPFEE1497 pKa = 4.24LFAQKK1502 pKa = 10.86GLDD1505 pKa = 3.71VIGGDD1510 pKa = 3.65MVDD1513 pKa = 3.82VLQGAANWTNRR1524 pKa = 11.84MQGGAGDD1531 pKa = 4.5DD1532 pKa = 3.94SLSGGSINDD1541 pKa = 3.5ILDD1544 pKa = 3.92GGDD1547 pKa = 3.51GNDD1550 pKa = 3.64WLDD1553 pKa = 3.57GGLGSDD1559 pKa = 4.23TLNGGAGNDD1568 pKa = 3.82QLSGGYY1574 pKa = 10.59GNDD1577 pKa = 3.14VLTGGAGNDD1586 pKa = 3.52TLFGGEE1592 pKa = 4.4GSDD1595 pKa = 3.77TYY1597 pKa = 11.1IFNQGDD1603 pKa = 4.35GVDD1606 pKa = 5.62LIADD1610 pKa = 3.97SNTAGQINTLRR1621 pKa = 11.84LGAGLTVPMLRR1632 pKa = 11.84LATTQDD1638 pKa = 3.33NGLLTLDD1645 pKa = 4.87FGNGDD1650 pKa = 3.54AVVIGGFNRR1659 pKa = 11.84NDD1661 pKa = 3.5LLAGLSIQRR1670 pKa = 11.84FEE1672 pKa = 4.46FVDD1675 pKa = 4.13GTVMTAQQLVDD1686 pKa = 4.1LGINVDD1692 pKa = 3.68GTTGDD1697 pKa = 3.92DD1698 pKa = 3.56VLLGSSSTDD1707 pKa = 3.08YY1708 pKa = 11.1MFGDD1712 pKa = 4.68DD1713 pKa = 5.25GNDD1716 pKa = 3.16VLLAGAGDD1724 pKa = 3.91DD1725 pKa = 4.66ALDD1728 pKa = 3.76GGYY1731 pKa = 11.12GNDD1734 pKa = 3.34VLSGEE1739 pKa = 4.44GGNDD1743 pKa = 2.83ILQGGIGYY1751 pKa = 9.72DD1752 pKa = 3.37VLYY1755 pKa = 10.86GGTGNDD1761 pKa = 3.04TYY1763 pKa = 11.6VFNYY1767 pKa = 10.58GDD1769 pKa = 3.8GQDD1772 pKa = 5.04RR1773 pKa = 11.84IIDD1776 pKa = 3.79NQGSNTLQFGAGIFASDD1793 pKa = 3.34VTFSKK1798 pKa = 10.58FGSDD1802 pKa = 3.65LQIDD1806 pKa = 4.44FSNGTDD1812 pKa = 3.64RR1813 pKa = 11.84IRR1815 pKa = 11.84VVDD1818 pKa = 3.82WFAGNSIEE1826 pKa = 4.67TLTFNDD1832 pKa = 4.12GTSLDD1837 pKa = 3.94LRR1839 pKa = 11.84AMEE1842 pKa = 4.85PSFADD1847 pKa = 3.49VPIVGTVADD1856 pKa = 5.52DD1857 pKa = 3.4ILTGSVGNDD1866 pKa = 3.12TLAGGQGNDD1875 pKa = 3.41TLIGGTGNDD1884 pKa = 3.08TYY1886 pKa = 11.42LFNLGDD1892 pKa = 4.2GVDD1895 pKa = 3.73QIYY1898 pKa = 10.49EE1899 pKa = 4.03LSGLGNPATDD1909 pKa = 3.23NSIVFGAGITPDD1921 pKa = 3.15MLSFNMEE1928 pKa = 3.92VVQATDD1934 pKa = 2.46AWRR1937 pKa = 11.84TGYY1940 pKa = 11.14GNTPSFPSTAADD1952 pKa = 3.41MAPNEE1957 pKa = 4.26TTRR1960 pKa = 11.84QVMTISVGAQGDD1972 pKa = 4.69AIQVMSGMNAIGKK1985 pKa = 9.09FKK1987 pKa = 10.57FADD1990 pKa = 3.94GSEE1993 pKa = 4.18FTLNEE1998 pKa = 4.73LITWQDD2004 pKa = 2.8AGLPTINDD2012 pKa = 4.37TINDD2016 pKa = 3.53PWRR2019 pKa = 11.84ASTLDD2024 pKa = 4.02GIGTSAVFNGGAGNDD2039 pKa = 3.35IVIGGDD2045 pKa = 3.09QYY2047 pKa = 12.12DD2048 pKa = 3.8SYY2050 pKa = 11.51TFNLGDD2056 pKa = 4.08GQDD2059 pKa = 3.76VIADD2063 pKa = 3.97LGGWNDD2069 pKa = 2.75IRR2071 pKa = 11.84FGAGITASDD2080 pKa = 3.6ITWNYY2085 pKa = 10.4DD2086 pKa = 3.31PASATPFVLNVGPYY2100 pKa = 9.82GDD2102 pKa = 5.11SIAIANGEE2110 pKa = 3.81QGIIQNFVFSDD2121 pKa = 3.82GTAITFDD2128 pKa = 3.63QLLAQQGGLPPVTPDD2143 pKa = 3.18IPKK2146 pKa = 10.28SLYY2149 pKa = 10.41SYY2151 pKa = 11.43NSGLLMGSNADD2162 pKa = 3.54DD2163 pKa = 4.64TINSDD2168 pKa = 3.29VSASSGAAVVVGGKK2182 pKa = 10.31GDD2184 pKa = 3.7DD2185 pKa = 3.56VMYY2188 pKa = 10.81GPNSTFLFNVGDD2200 pKa = 4.13GQDD2203 pKa = 3.61TIQNKK2208 pKa = 9.0GWGSSYY2214 pKa = 10.89NDD2216 pKa = 2.91SGMTLLFGTGITPDD2230 pKa = 2.93ASFNIEE2236 pKa = 4.12VIEE2239 pKa = 4.43KK2240 pKa = 10.69KK2241 pKa = 9.3NTGQLWSRR2249 pKa = 11.84QGQLGLDD2256 pKa = 3.72SQDD2259 pKa = 2.81ISIGYY2264 pKa = 8.77GNQGDD2269 pKa = 3.73QVFIQDD2275 pKa = 4.06AYY2277 pKa = 10.02TFQAGQNQVPGSLPSAWDD2295 pKa = 3.01WWSGEE2300 pKa = 3.83AQTIQSIRR2308 pKa = 11.84KK2309 pKa = 8.18IEE2311 pKa = 4.02FANGVIWNYY2320 pKa = 9.65EE2321 pKa = 4.23DD2322 pKa = 3.47IMAHH2326 pKa = 5.48ATHH2329 pKa = 6.41IVEE2332 pKa = 4.82DD2333 pKa = 3.8AASALVTGTGYY2344 pKa = 10.85NDD2346 pKa = 4.95RR2347 pKa = 11.84IFAYY2351 pKa = 10.04AGNSVLSGGLGNDD2364 pKa = 3.42TYY2366 pKa = 11.46VISEE2370 pKa = 4.26SGDD2373 pKa = 3.38YY2374 pKa = 10.64TITDD2378 pKa = 3.56SCGVGSGNNTVEE2390 pKa = 4.28FAWNYY2395 pKa = 10.16ADD2397 pKa = 5.65SNFTLSNEE2405 pKa = 4.23SGLTLNFDD2413 pKa = 3.29NGATVRR2419 pKa = 11.84LGGFDD2424 pKa = 4.19PNDD2427 pKa = 3.77PQASCSIDD2435 pKa = 3.23SFKK2438 pKa = 11.04FADD2441 pKa = 4.32GTALTYY2447 pKa = 10.66DD2448 pKa = 3.33QLLTRR2453 pKa = 11.84GIDD2456 pKa = 3.62MQGSAASEE2464 pKa = 4.46VIEE2467 pKa = 4.23GTAVNDD2473 pKa = 5.4RR2474 pKa = 11.84IDD2476 pKa = 4.19ALDD2479 pKa = 4.09GNDD2482 pKa = 3.93TIIGGKK2488 pKa = 10.39GNDD2491 pKa = 3.15ILRR2494 pKa = 11.84GGEE2497 pKa = 4.02GGDD2500 pKa = 3.34TYY2502 pKa = 11.35AYY2504 pKa = 10.62DD2505 pKa = 4.66LGDD2508 pKa = 3.92GTDD2511 pKa = 3.74TIIDD2515 pKa = 4.13QGWHH2519 pKa = 4.43WNGNVLVADD2528 pKa = 4.49EE2529 pKa = 4.58NTLQLGSGIDD2539 pKa = 3.46QSNVSVSFNADD2550 pKa = 2.67TGSIVLKK2557 pKa = 9.8MADD2560 pKa = 3.96GGSIDD2565 pKa = 4.53LGQPGAFSVQKK2576 pKa = 10.66VQFADD2581 pKa = 3.83GTSWDD2586 pKa = 3.36EE2587 pKa = 3.97WGVIAHH2593 pKa = 6.84LPGGNGNNLAPTQSGALLDD2612 pKa = 3.81QDD2614 pKa = 3.91ATQDD2618 pKa = 3.47QAFTYY2623 pKa = 8.73QIPDD2627 pKa = 3.41SVFADD2632 pKa = 3.77PNGDD2636 pKa = 3.35RR2637 pKa = 11.84LSYY2640 pKa = 10.16SVAMADD2646 pKa = 4.12GSAVPAWLQFDD2657 pKa = 4.64PLTQTFTGTPEE2668 pKa = 4.0NADD2671 pKa = 3.29VRR2673 pKa = 11.84SLNLSVTATDD2683 pKa = 3.64AGGLSTSGTFILNVLNVNDD2702 pKa = 4.13APVVSMALTDD2712 pKa = 3.5QTVQEE2717 pKa = 4.38SAEE2720 pKa = 4.08FTFAVPDD2727 pKa = 3.98GAFTDD2732 pKa = 3.14IDD2734 pKa = 3.93MNYY2737 pKa = 9.91GDD2739 pKa = 4.46SLIYY2743 pKa = 10.57SATLTDD2749 pKa = 4.99GSALPAWLTFDD2760 pKa = 3.86AGAGVFSGVPAHH2772 pKa = 6.83GDD2774 pKa = 3.36VGVLDD2779 pKa = 4.1VAVTATDD2786 pKa = 3.23IDD2788 pKa = 4.27GLTASTTFRR2797 pKa = 11.84LDD2799 pKa = 3.0IAGVAPSNQAPVANGDD2815 pKa = 4.03TVTLDD2820 pKa = 3.43QNSGQSIITASSLLANDD2837 pKa = 4.5TDD2839 pKa = 4.46PDD2841 pKa = 3.64MGDD2844 pKa = 3.23TLNIVSVDD2852 pKa = 3.17ATSALGNSVMLGAAGDD2868 pKa = 3.89VVFDD2872 pKa = 4.65IGNKK2876 pKa = 8.91YY2877 pKa = 9.54QLLGAGQTAIDD2888 pKa = 3.74TFNYY2892 pKa = 8.53TVADD2896 pKa = 4.21GSGATATATVTATITGVNDD2915 pKa = 3.73APVTTADD2922 pKa = 3.33VATAMQEE2929 pKa = 4.09DD2930 pKa = 4.45LAVTVMGNVLANDD2943 pKa = 3.62TDD2945 pKa = 3.78IDD2947 pKa = 3.8QGTVLAVANAGTFAGQYY2964 pKa = 9.6GQLALNADD2972 pKa = 3.71GSYY2975 pKa = 10.25TYY2977 pKa = 11.51ALDD2980 pKa = 3.81NASLGVQSLAEE2991 pKa = 4.1GQVVTEE2997 pKa = 4.27TFAYY3001 pKa = 9.88QATDD3005 pKa = 3.44GLVATPSTLTVTIIGTNDD3023 pKa = 2.9APIATVDD3030 pKa = 3.48TTTVQEE3036 pKa = 4.43DD3037 pKa = 4.19VSVTASGNVLSNDD3050 pKa = 3.11ADD3052 pKa = 3.61VDD3054 pKa = 3.69QGTVLSVANVGVFIGQFGQLTLNADD3079 pKa = 3.51GSYY3082 pKa = 10.21TYY3084 pKa = 11.49ALDD3087 pKa = 3.8NNALAVQSLAEE3098 pKa = 4.15GQVVTEE3104 pKa = 4.11SFAYY3108 pKa = 9.43QASDD3112 pKa = 4.48GITSTPSTLTISITGTNDD3130 pKa = 3.07APVVAADD3137 pKa = 3.8TAAVQEE3143 pKa = 4.72DD3144 pKa = 4.15LSITAIGNVLANDD3157 pKa = 3.27IDD3159 pKa = 3.97IDD3161 pKa = 3.75QGAVLSVANTGMFAGHH3177 pKa = 6.45YY3178 pKa = 9.39GQLNLNADD3186 pKa = 3.5GSYY3189 pKa = 10.26TYY3191 pKa = 10.65TLDD3194 pKa = 3.58NASLGVQSLAEE3205 pKa = 4.1GQVVTEE3211 pKa = 4.27TFAYY3215 pKa = 9.94QATDD3219 pKa = 4.92GITSTPSTLTVTITGTNDD3237 pKa = 3.05APVTTVDD3244 pKa = 3.34TAAVQEE3250 pKa = 5.12DD3251 pKa = 3.85ISIAASGNVLANDD3264 pKa = 3.61SDD3266 pKa = 4.0VDD3268 pKa = 3.48QGTVLGVANAGEE3280 pKa = 4.22FAGQYY3285 pKa = 9.9GQLTLQADD3293 pKa = 4.36GSYY3296 pKa = 10.33TYY3298 pKa = 11.31VLDD3301 pKa = 4.06NASSAVQSLAAGQVITEE3318 pKa = 4.45TFAYY3322 pKa = 9.82QATDD3326 pKa = 3.59GLVSTPSSLTVTITCTNDD3344 pKa = 2.87APIVAVPLPDD3354 pKa = 3.7SSTLEE3359 pKa = 3.75DD3360 pKa = 3.57QIFHH3364 pKa = 6.04FQVPADD3370 pKa = 3.92TFTDD3374 pKa = 3.24IDD3376 pKa = 3.56QGDD3379 pKa = 4.27VLTYY3383 pKa = 9.84HH3384 pKa = 6.84ATMADD3389 pKa = 3.62GSVLPDD3395 pKa = 3.4WLTFDD3400 pKa = 3.48ATTLTFSGVPSNWDD3414 pKa = 2.93VGVFNVSVTATDD3426 pKa = 3.26TGGLSATDD3434 pKa = 3.69TFTLDD3439 pKa = 3.34VQNVNDD3445 pKa = 4.09APVVLNHH3452 pKa = 6.48MADD3455 pKa = 3.18QHH3457 pKa = 6.21IAEE3460 pKa = 4.43SHH3462 pKa = 6.61CDD3464 pKa = 3.44DD3465 pKa = 3.2HH3466 pKa = 8.75HH3467 pKa = 6.52GFSFAVPANTFDD3479 pKa = 4.04DD3480 pKa = 3.63WDD3482 pKa = 3.86IVHH3485 pKa = 7.15GDD3487 pKa = 3.53SLTYY3491 pKa = 9.84SATMADD3497 pKa = 4.61GEE3499 pKa = 5.39KK3500 pKa = 10.41LPCWLKK3506 pKa = 10.68FDD3508 pKa = 4.92AATCTFSGRR3517 pKa = 11.84AEE3519 pKa = 4.57DD3520 pKa = 3.77SGNWDD3525 pKa = 3.07ILLTVTDD3532 pKa = 3.83RR3533 pKa = 11.84AGASVSQVFNLSSGDD3548 pKa = 3.6DD3549 pKa = 3.86HH3550 pKa = 7.94RR3551 pKa = 11.84DD3552 pKa = 3.14KK3553 pKa = 11.58CHH3555 pKa = 7.48DD3556 pKa = 4.08DD3557 pKa = 3.27QVLPIDD3563 pKa = 3.8TTQDD3567 pKa = 3.41EE3568 pKa = 5.5IITSSSVNDD3577 pKa = 4.26IIHH3580 pKa = 6.62TGNGANTIVFMRR3592 pKa = 11.84GYY3594 pKa = 10.34GQDD3597 pKa = 3.12KK3598 pKa = 10.09VYY3600 pKa = 11.21GSIGTDD3606 pKa = 3.02NTVVLGGGIQMADD3619 pKa = 2.83IALSKK3624 pKa = 10.52QGNDD3628 pKa = 4.34LILEE3632 pKa = 4.43SGNNDD3637 pKa = 3.3QITFKK3642 pKa = 10.65NWYY3645 pKa = 6.27DD3646 pKa = 3.44TNVNHH3651 pKa = 7.44KK3652 pKa = 10.44SVLNLEE3658 pKa = 4.8IISNAMSGFGEE3669 pKa = 4.52DD3670 pKa = 3.3NHH3672 pKa = 7.15HH3673 pKa = 6.63GKK3675 pKa = 9.58HH3676 pKa = 6.78DD3677 pKa = 3.65DD3678 pKa = 3.62HH3679 pKa = 9.24LSIRR3683 pKa = 11.84HH3684 pKa = 5.76FDD3686 pKa = 3.35FTAVVNAFDD3695 pKa = 4.56QALTTNPALNAWSMTDD3711 pKa = 3.3ALLSAHH3717 pKa = 7.12LEE3719 pKa = 4.45GCDD3722 pKa = 3.64SSTLGGDD3729 pKa = 4.25LANQFNQNGSLAAIALASSQTAINDD3754 pKa = 3.86TNFGGIPQQLHH3765 pKa = 6.47PFAGLQTTTAKK3776 pKa = 10.74LGG3778 pKa = 3.51

Molecular weight:
392.42 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>tr|D5CQK7|D5CQK7_SIDLE Glutaredoxin 2 OS=Sideroxydans lithotrophicus (strain ES-1) OX=580332 GN=Slit_1005 PE=4 SV=1
MM1 pKa = 7.35KK2 pKa = 9.36RR3 pKa = 11.84TYY5 pKa = 10.14QPSVTKK11 pKa = 10.56RR12 pKa = 11.84KK13 pKa = 7.91RR14 pKa = 11.84THH16 pKa = 5.88GFLVRR21 pKa = 11.84MKK23 pKa = 9.4TKK25 pKa = 10.36GGRR28 pKa = 11.84AVIAARR34 pKa = 11.84RR35 pKa = 11.84ARR37 pKa = 11.84GRR39 pKa = 11.84VRR41 pKa = 11.84LGVV44 pKa = 3.29

Molecular weight:
5.05 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

2977

0

2977

913564

30

3778

306.9

33.81

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

10.503 ± 0.054

1.01 ± 0.021

5.32 ± 0.046

5.897 ± 0.055

3.789 ± 0.028

7.565 ± 0.048

2.455 ± 0.029

5.498 ± 0.032

4.609 ± 0.042

10.624 ± 0.06

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.778 ± 0.022

3.469 ± 0.037

4.409 ± 0.031

4.16 ± 0.035

5.836 ± 0.048

5.78 ± 0.035

5.152 ± 0.054

7.17 ± 0.037

1.264 ± 0.019

2.714 ± 0.023

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski