Amino acid dipepetide frequency for Lactobacillus parafarraginis F0439

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.282AlaAla: 8.282 ± 0.327	0.405AlaCys: 0.405 ± 0.022	5.444AlaAsp: 5.444 ± 0.091	3.718AlaGlu: 3.718 ± 0.078	3.454AlaPhe: 3.454 ± 0.073	6.005AlaGly: 6.005 ± 0.099	1.656AlaHis: 1.656 ± 0.049	6.109AlaIle: 6.109 ± 0.095	5.867AlaLys: 5.867 ± 0.102	7.082AlaLeu: 7.082 ± 0.093	2.16AlaMet: 2.16 ± 0.058	4.263AlaAsn: 4.263 ± 0.098	2.403AlaPro: 2.403 ± 0.062	3.273AlaGln: 3.273 ± 0.073	2.806AlaArg: 2.806 ± 0.061	5.169AlaSer: 5.169 ± 0.246	5.292AlaThr: 5.292 ± 0.091	5.877AlaVal: 5.877 ± 0.087	0.67AlaTrp: 0.67 ± 0.032	2.683AlaTyr: 2.683 ± 0.057	0.0AlaXaa: 0.0 ± 0.0
Cys	0.347CysAla: 0.347 ± 0.022	0.052CysCys: 0.052 ± 0.007	0.273CysAsp: 0.273 ± 0.02	0.228CysGlu: 0.228 ± 0.019	0.234CysPhe: 0.234 ± 0.019	0.467CysGly: 0.467 ± 0.023	0.165CysHis: 0.165 ± 0.015	0.255CysIle: 0.255 ± 0.018	0.148CysLys: 0.148 ± 0.015	0.525CysLeu: 0.525 ± 0.028	0.124CysMet: 0.124 ± 0.011	0.192CysAsn: 0.192 ± 0.014	0.231CysPro: 0.231 ± 0.021	0.213CysGln: 0.213 ± 0.015	0.233CysArg: 0.233 ± 0.017	0.318CysSer: 0.318 ± 0.021	0.223CysThr: 0.223 ± 0.016	0.327CysVal: 0.327 ± 0.02	0.064CysTrp: 0.064 ± 0.009	0.168CysTyr: 0.168 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	4.629AspAla: 4.629 ± 0.119	0.233AspCys: 0.233 ± 0.016	3.942AspAsp: 3.942 ± 0.088	3.47AspGlu: 3.47 ± 0.082	2.683AspPhe: 2.683 ± 0.061	3.796AspGly: 3.796 ± 0.072	1.711AspHis: 1.711 ± 0.052	3.583AspIle: 3.583 ± 0.07	3.605AspLys: 3.605 ± 0.075	5.49AspLeu: 5.49 ± 0.08	1.531AspMet: 1.531 ± 0.04	2.649AspAsn: 2.649 ± 0.065	2.661AspPro: 2.661 ± 0.063	3.625AspGln: 3.625 ± 0.072	2.601AspArg: 2.601 ± 0.056	3.255AspSer: 3.255 ± 0.065	2.899AspThr: 2.899 ± 0.064	4.116AspVal: 4.116 ± 0.078	0.728AspTrp: 0.728 ± 0.03	2.516AspTyr: 2.516 ± 0.06	0.0AspXaa: 0.0 ± 0.0
Glu	3.797GluAla: 3.797 ± 0.077	0.149GluCys: 0.149 ± 0.014	2.487GluAsp: 2.487 ± 0.056	2.289GluGlu: 2.289 ± 0.06	1.888GluPhe: 1.888 ± 0.05	2.352GluGly: 2.352 ± 0.057	0.961GluHis: 0.961 ± 0.036	3.517GluIle: 3.517 ± 0.078	3.53GluLys: 3.53 ± 0.075	4.726GluLeu: 4.726 ± 0.096	1.533GluMet: 1.533 ± 0.039	2.492GluAsn: 2.492 ± 0.061	1.63GluPro: 1.63 ± 0.048	2.031GluGln: 2.031 ± 0.057	2.122GluArg: 2.122 ± 0.06	2.65GluSer: 2.65 ± 0.057	2.833GluThr: 2.833 ± 0.062	3.102GluVal: 3.102 ± 0.065	0.455GluTrp: 0.455 ± 0.025	1.453GluTyr: 1.453 ± 0.042	0.0GluXaa: 0.0 ± 0.0
Phe	3.271PheAla: 3.271 ± 0.067	0.283PheCys: 0.283 ± 0.018	2.968PheAsp: 2.968 ± 0.069	2.109PheGlu: 2.109 ± 0.052	2.045PhePhe: 2.045 ± 0.058	3.578PheGly: 3.578 ± 0.078	0.949PheHis: 0.949 ± 0.032	2.96PheIle: 2.96 ± 0.063	2.629PheLys: 2.629 ± 0.062	3.726PheLeu: 3.726 ± 0.077	1.125PheMet: 1.125 ± 0.044	2.367PheAsn: 2.367 ± 0.06	1.628PhePro: 1.628 ± 0.044	1.497PheGln: 1.497 ± 0.037	1.481PheArg: 1.481 ± 0.043	3.119PheSer: 3.119 ± 0.071	2.537PheThr: 2.537 ± 0.062	3.066PheVal: 3.066 ± 0.063	0.587PheTrp: 0.587 ± 0.028	1.632PheTyr: 1.632 ± 0.045	0.0PheXaa: 0.0 ± 0.0
Gly	4.97GlyAla: 4.97 ± 0.094	0.413GlyCys: 0.413 ± 0.022	3.63GlyAsp: 3.63 ± 0.072	2.956GlyGlu: 2.956 ± 0.07	3.254GlyPhe: 3.254 ± 0.075	4.688GlyGly: 4.688 ± 0.105	1.698GlyHis: 1.698 ± 0.047	5.801GlyIle: 5.801 ± 0.101	4.585GlyLys: 4.585 ± 0.075	6.554GlyLeu: 6.554 ± 0.108	2.026GlyMet: 2.026 ± 0.054	3.094GlyAsn: 3.094 ± 0.071	1.729GlyPro: 1.729 ± 0.048	2.851GlyGln: 2.851 ± 0.07	2.666GlyArg: 2.666 ± 0.06	4.327GlySer: 4.327 ± 0.075	4.387GlyThr: 4.387 ± 0.085	5.011GlyVal: 5.011 ± 0.08	0.824GlyTrp: 0.824 ± 0.034	2.84GlyTyr: 2.84 ± 0.068	0.0GlyXaa: 0.0 ± 0.0
His	1.523HisAla: 1.523 ± 0.042	0.125HisCys: 0.125 ± 0.013	1.377HisAsp: 1.377 ± 0.044	1.186HisGlu: 1.186 ± 0.036	1.234HisPhe: 1.234 ± 0.038	1.673HisGly: 1.673 ± 0.045	0.866HisHis: 0.866 ± 0.032	1.326HisIle: 1.326 ± 0.04	1.033HisLys: 1.033 ± 0.036	2.209HisLeu: 2.209 ± 0.054	0.575HisMet: 0.575 ± 0.027	1.001HisAsn: 1.001 ± 0.036	1.226HisPro: 1.226 ± 0.042	1.371HisGln: 1.371 ± 0.038	1.087HisArg: 1.087 ± 0.039	1.29HisSer: 1.29 ± 0.039	1.134HisThr: 1.134 ± 0.037	1.536HisVal: 1.536 ± 0.042	0.294HisTrp: 0.294 ± 0.017	1.048HisTyr: 1.048 ± 0.037	0.0HisXaa: 0.0 ± 0.0
Ile	6.172IleAla: 6.172 ± 0.11	0.471IleCys: 0.471 ± 0.024	4.491IleAsp: 4.491 ± 0.081	3.162IleGlu: 3.162 ± 0.075	3.062IlePhe: 3.062 ± 0.071	5.505IleGly: 5.505 ± 0.107	1.491IleHis: 1.491 ± 0.044	4.98IleIle: 4.98 ± 0.098	4.263IleLys: 4.263 ± 0.06	6.404IleLeu: 6.404 ± 0.113	1.847IleMet: 1.847 ± 0.054	3.602IleAsn: 3.602 ± 0.069	2.889IlePro: 2.889 ± 0.057	2.662IleGln: 2.662 ± 0.06	2.693IleArg: 2.693 ± 0.066	5.021IleSer: 5.021 ± 0.077	4.311IleThr: 4.311 ± 0.086	5.177IleVal: 5.177 ± 0.084	0.662IleTrp: 0.662 ± 0.028	2.249IleTyr: 2.249 ± 0.049	0.0IleXaa: 0.0 ± 0.0
Lys	4.988LysAla: 4.988 ± 0.096	0.185LysCys: 0.185 ± 0.016	3.575LysAsp: 3.575 ± 0.079	2.74LysGlu: 2.74 ± 0.061	2.173LysPhe: 2.173 ± 0.053	3.29LysGly: 3.29 ± 0.069	1.364LysHis: 1.364 ± 0.043	4.319LysIle: 4.319 ± 0.077	4.723LysLys: 4.723 ± 0.085	5.83LysLeu: 5.83 ± 0.084	2.153LysMet: 2.153 ± 0.046	3.318LysAsn: 3.318 ± 0.073	2.582LysPro: 2.582 ± 0.054	3.571LysGln: 3.571 ± 0.078	3.293LysArg: 3.293 ± 0.072	3.855LysSer: 3.855 ± 0.082	4.095LysThr: 4.095 ± 0.083	4.378LysVal: 4.378 ± 0.073	0.669LysTrp: 0.669 ± 0.025	2.314LysTyr: 2.314 ± 0.063	0.0LysXaa: 0.0 ± 0.0
Leu	8.295LeuAla: 8.295 ± 0.113	0.484LeuCys: 0.484 ± 0.026	5.138LeuAsp: 5.138 ± 0.107	3.751LeuGlu: 3.751 ± 0.072	4.118LeuPhe: 4.118 ± 0.081	6.411LeuGly: 6.411 ± 0.101	1.738LeuHis: 1.738 ± 0.052	7.104LeuIle: 7.104 ± 0.123	6.289LeuLys: 6.289 ± 0.081	8.286LeuLeu: 8.286 ± 0.13	2.517LeuMet: 2.517 ± 0.07	4.867LeuAsn: 4.867 ± 0.078	4.05LeuPro: 4.05 ± 0.065	3.195LeuGln: 3.195 ± 0.072	3.52LeuArg: 3.52 ± 0.068	6.66LeuSer: 6.66 ± 0.09	6.735LeuThr: 6.735 ± 0.098	6.422LeuVal: 6.422 ± 0.083	0.829LeuTrp: 0.829 ± 0.035	2.647LeuTyr: 2.647 ± 0.062	0.0LeuXaa: 0.0 ± 0.0
Met	2.65MetAla: 2.65 ± 0.064	0.115MetCys: 0.115 ± 0.013	1.424MetAsp: 1.424 ± 0.045	0.956MetGlu: 0.956 ± 0.034	1.005MetPhe: 1.005 ± 0.04	1.909MetGly: 1.909 ± 0.057	0.483MetHis: 0.483 ± 0.023	2.209MetIle: 2.209 ± 0.053	1.891MetLys: 1.891 ± 0.05	2.304MetLeu: 2.304 ± 0.061	0.866MetMet: 0.866 ± 0.032	1.419MetAsn: 1.419 ± 0.037	1.153MetPro: 1.153 ± 0.039	1.005MetGln: 1.005 ± 0.035	1.101MetArg: 1.101 ± 0.035	1.592MetSer: 1.592 ± 0.046	2.103MetThr: 2.103 ± 0.051	1.864MetVal: 1.864 ± 0.05	0.241MetTrp: 0.241 ± 0.017	0.681MetTyr: 0.681 ± 0.032	0.0MetXaa: 0.0 ± 0.0
Asn	3.913AsnAla: 3.913 ± 0.087	0.231AsnCys: 0.231 ± 0.018	3.073AsnAsp: 3.073 ± 0.057	2.435AsnGlu: 2.435 ± 0.058	1.986AsnPhe: 1.986 ± 0.049	3.781AsnGly: 3.781 ± 0.083	1.473AsnHis: 1.473 ± 0.041	2.74AsnIle: 2.74 ± 0.062	2.567AsnLys: 2.567 ± 0.061	4.438AsnLeu: 4.438 ± 0.074	1.278AsnMet: 1.278 ± 0.039	2.472AsnAsn: 2.472 ± 0.063	2.374AsnPro: 2.374 ± 0.055	3.01AsnGln: 3.01 ± 0.077	2.502AsnArg: 2.502 ± 0.067	2.906AsnSer: 2.906 ± 0.073	2.588AsnThr: 2.588 ± 0.063	3.368AsnVal: 3.368 ± 0.06	0.653AsnTrp: 0.653 ± 0.028	1.866AsnTyr: 1.866 ± 0.051	0.0AsnXaa: 0.0 ± 0.0
Pro	3.191ProAla: 3.191 ± 0.071	0.134ProCys: 0.134 ± 0.014	2.665ProAsp: 2.665 ± 0.056	2.641ProGlu: 2.641 ± 0.059	1.858ProPhe: 1.858 ± 0.049	2.324ProGly: 2.324 ± 0.054	0.771ProHis: 0.771 ± 0.032	2.779ProIle: 2.779 ± 0.057	2.6ProLys: 2.6 ± 0.057	3.348ProLeu: 3.348 ± 0.078	0.874ProMet: 0.874 ± 0.033	2.038ProAsn: 2.038 ± 0.052	0.707ProPro: 0.707 ± 0.035	1.636ProGln: 1.636 ± 0.041	1.274ProArg: 1.274 ± 0.041	2.282ProSer: 2.282 ± 0.052	2.725ProThr: 2.725 ± 0.079	3.043ProVal: 3.043 ± 0.078	0.415ProTrp: 0.415 ± 0.024	1.373ProTyr: 1.373 ± 0.045	0.0ProXaa: 0.0 ± 0.0
Gln	3.821GlnAla: 3.821 ± 0.074	0.128GlnCys: 0.128 ± 0.013	1.965GlnAsp: 1.965 ± 0.051	1.84GlnGlu: 1.84 ± 0.047	1.979GlnPhe: 1.979 ± 0.047	2.219GlnGly: 2.219 ± 0.057	1.001GlnHis: 1.001 ± 0.037	3.369GlnIle: 3.369 ± 0.071	2.908GlnLys: 2.908 ± 0.069	5.101GlnLeu: 5.101 ± 0.087	1.201GlnMet: 1.201 ± 0.036	2.145GlnAsn: 2.145 ± 0.054	1.83GlnPro: 1.83 ± 0.053	2.393GlnGln: 2.393 ± 0.068	2.179GlnArg: 2.179 ± 0.059	2.911GlnSer: 2.911 ± 0.068	2.989GlnThr: 2.989 ± 0.073	3.061GlnVal: 3.061 ± 0.063	0.456GlnTrp: 0.456 ± 0.023	1.633GlnTyr: 1.633 ± 0.046	0.0GlnXaa: 0.0 ± 0.0
Arg	2.78ArgAla: 2.78 ± 0.062	0.181ArgCys: 0.181 ± 0.017	2.35ArgAsp: 2.35 ± 0.056	2.094ArgGlu: 2.094 ± 0.052	1.961ArgPhe: 1.961 ± 0.05	2.465ArgGly: 2.465 ± 0.052	1.184ArgHis: 1.184 ± 0.04	2.948ArgIle: 2.948 ± 0.067	2.575ArgLys: 2.575 ± 0.057	4.151ArgLeu: 4.151 ± 0.074	1.136ArgMet: 1.136 ± 0.038	1.949ArgAsn: 1.949 ± 0.045	1.621ArgPro: 1.621 ± 0.047	2.344ArgGln: 2.344 ± 0.057	2.177ArgArg: 2.177 ± 0.057	2.259ArgSer: 2.259 ± 0.056	2.207ArgThr: 2.207 ± 0.059	2.836ArgVal: 2.836 ± 0.07	0.384ArgTrp: 0.384 ± 0.02	1.784ArgTyr: 1.784 ± 0.052	0.0ArgXaa: 0.0 ± 0.0
Ser	5.165SerAla: 5.165 ± 0.161	0.255SerCys: 0.255 ± 0.017	4.064SerAsp: 4.064 ± 0.116	2.905SerGlu: 2.905 ± 0.069	2.953SerPhe: 2.953 ± 0.072	4.982SerGly: 4.982 ± 0.081	1.469SerHis: 1.469 ± 0.038	4.007SerIle: 4.007 ± 0.074	3.862SerLys: 3.862 ± 0.067	6.002SerLeu: 6.002 ± 0.097	1.715SerMet: 1.715 ± 0.051	2.959SerAsn: 2.959 ± 0.081	2.291SerPro: 2.291 ± 0.051	3.008SerGln: 3.008 ± 0.075	2.627SerArg: 2.627 ± 0.056	4.192SerSer: 4.192 ± 0.115	3.765SerThr: 3.765 ± 0.08	4.185SerVal: 4.185 ± 0.068	0.676SerTrp: 0.676 ± 0.031	2.155SerTyr: 2.155 ± 0.056	0.0SerXaa: 0.0 ± 0.0
Thr	5.368ThrAla: 5.368 ± 0.099	0.267ThrCys: 0.267 ± 0.02	3.75ThrAsp: 3.75 ± 0.071	2.566ThrGlu: 2.566 ± 0.054	2.618ThrPhe: 2.618 ± 0.058	4.736ThrGly: 4.736 ± 0.081	1.375ThrHis: 1.375 ± 0.04	4.88ThrIle: 4.88 ± 0.073	3.815ThrLys: 3.815 ± 0.072	5.532ThrLeu: 5.532 ± 0.089	1.488ThrMet: 1.488 ± 0.042	3.153ThrAsn: 3.153 ± 0.069	3.045ThrPro: 3.045 ± 0.088	2.256ThrGln: 2.256 ± 0.056	2.142ThrArg: 2.142 ± 0.046	3.861ThrSer: 3.861 ± 0.08	4.498ThrThr: 4.498 ± 0.106	4.803ThrVal: 4.803 ± 0.085	0.634ThrTrp: 0.634 ± 0.028	2.176ThrTyr: 2.176 ± 0.054	0.0ThrXaa: 0.0 ± 0.0
Val	6.227ValAla: 6.227 ± 0.104	0.403ValCys: 0.403 ± 0.023	4.431ValAsp: 4.431 ± 0.082	3.015ValGlu: 3.015 ± 0.081	2.746ValPhe: 2.746 ± 0.072	5.025ValGly: 5.025 ± 0.088	1.369ValHis: 1.369 ± 0.041	5.437ValIle: 5.437 ± 0.071	4.383ValLys: 4.383 ± 0.087	6.197ValLeu: 6.197 ± 0.099	1.774ValMet: 1.774 ± 0.041	3.611ValAsn: 3.611 ± 0.069	2.835ValPro: 2.835 ± 0.05	2.327ValGln: 2.327 ± 0.055	2.471ValArg: 2.471 ± 0.053	4.836ValSer: 4.836 ± 0.088	5.157ValThr: 5.157 ± 0.089	5.207ValVal: 5.207 ± 0.088	0.686ValTrp: 0.686 ± 0.028	2.254ValTyr: 2.254 ± 0.049	0.0ValXaa: 0.0 ± 0.0
Trp	0.711TrpAla: 0.711 ± 0.03	0.052TrpCys: 0.052 ± 0.008	0.514TrpAsp: 0.514 ± 0.023	0.371TrpGlu: 0.371 ± 0.021	0.545TrpPhe: 0.545 ± 0.028	0.645TrpGly: 0.645 ± 0.028	0.291TrpHis: 0.291 ± 0.02	0.776TrpIle: 0.776 ± 0.034	0.503TrpLys: 0.503 ± 0.026	1.359TrpLeu: 1.359 ± 0.049	0.282TrpMet: 0.282 ± 0.02	0.526TrpAsn: 0.526 ± 0.027	0.337TrpPro: 0.337 ± 0.021	0.632TrpGln: 0.632 ± 0.028	0.57TrpArg: 0.57 ± 0.031	0.579TrpSer: 0.579 ± 0.029	0.558TrpThr: 0.558 ± 0.03	0.706TrpVal: 0.706 ± 0.027	0.153TrpTrp: 0.153 ± 0.014	0.414TrpTyr: 0.414 ± 0.024	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.518TyrAla: 2.518 ± 0.057	0.219TyrCys: 0.219 ± 0.017	2.163TyrAsp: 2.163 ± 0.051	1.563TyrGlu: 1.563 ± 0.046	1.762TyrPhe: 1.762 ± 0.047	2.451TyrGly: 2.451 ± 0.056	1.101TyrHis: 1.101 ± 0.036	2.014TyrIle: 2.014 ± 0.051	1.64TyrLys: 1.64 ± 0.044	3.789TyrLeu: 3.789 ± 0.077	0.767TyrMet: 0.767 ± 0.033	1.539TyrAsn: 1.539 ± 0.044	1.452TyrPro: 1.452 ± 0.045	2.229TyrGln: 2.229 ± 0.058	1.842TyrArg: 1.842 ± 0.046	2.155TyrSer: 2.155 ± 0.055	1.929TyrThr: 1.929 ± 0.048	2.309TyrVal: 2.309 ± 0.051	0.444TyrTrp: 0.444 ± 0.027	1.499TyrTyr: 1.499 ± 0.049	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3183 proteins (832771 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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